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| Product | Description | |
|---|---|---|
| arginine kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. This enzyme participates in arginine and proline metabolism. Group: Enzymes. Synonyms: arginine phosphokinase; adenosine 5'-triphosphate: L-arginine phosphotransferase; adenosine 5'-triphosphate-arginine phosphotransferase; ATP:L-arginine N-phosphotransferasel ATP:L-arginine ω-N-phosphotransferase. Enzyme Commission Number: EC 2.7.3.3. CAS No. 9026-70-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3183; arginine kinase; EC 2.7.3.3; 9026-70-4; arginine phosphokinase; adenosine 5'-triphosphate: L-arginine phosphotransferase; adenosine 5'-triphosphate-arginine phosphotransferase; ATP:L-arginine N-phosphotransferasel ATP:L-arginine ω-N-phosphotransferase. Cat No: EXWM-3183. |  |
| protein arginine kinase | The enzyme, characterized from Gram-positive bacteria, is involved in the regulation of the bacterial stress response. Group: Enzymes. Synonyms: McsB. Enzyme Commission Number: EC 2.7.14.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3166; protein arginine kinase; EC 2.7.14.1; McsB. Cat No: EXWM-3166. | |
| SRPK Inhibitor, SRPIN340 (N- (2-Piperidin-1-yl-5- (trifluoromethyl) phenyl) isonicotinamide, Serine-Arginine-Rich Protein Kinase Inhibitor, SR Protein Kinase Inhibitor, SR Protein Phosphorylation Inhibitor 340, (SRPIN)340) | A cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50 = 0.14 and 1.8uM, respectively, against mSRPK1 and mSRPK2) with much reduced activity against 143 other kinases. Shown to effectively counteract IGF-1-induced anti-angiogenic to pro-angiogenic VEGF isoforms switch both in cultures in vitro (1h 10uM SRPIN340 prior to 12h IGF-1 stimulation of PCIPs) and in a murine hypoxia-induced retinal neovascularization model in vivo (10pmol/uL/eye intraocular SRPIN340 injection) by inhibiting PKC/SRPK signaling-dependent, alternate splicing factor ASF- (SF2; splicing factor 2) mediated VEGF pro-mRNA PSS (proximal splice site) selection. Suppresses RNA virus Sindbis propagation (IC50 = 60uM in Vero cultures) and HCV-JFH1 replication (1 & 10uM SRPIN340 in Huh7.5.1 cultures). Exhibits no toxicity toward rats (2g/kg p.o. for 2 wks), CHO (5mg/ml for 24h), or Huh7 (30uM for 48h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| agmatine kinase | L-Arginine can act as acceptor, but more slowly. Group: Enzymes. Synonyms: phosphagen phosphokinase; ATP:agmatine 4-N-phosphotransferase. Enzyme Commission Number: EC 2.7.3.10. CAS No. 9076-75-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3181; agmatine kinase; EC 2.7.3.10; 9076-75-9; phosphagen phosphokinase; ATP:agmatine 4-N-phosphotransferase. Cat No: EXWM-3181. | |
| AMARA peptide TFA | AMARA peptide TFA is a substrate for salt-induced kinase (SIK) and adenosine monophosphate-activated protein kinase (AMPK). Synonyms: Ala-Met-Ala-Arg-Ala-Ala-Ser-Ala-Ala-Ala-Leu-Ala-Arg-Arg-Arg.TFA; L-alanyl-L-methionyl-L-alanyl-L-arginyl-L-alanyl-L-alanyl-L-seryl-L-alanyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-arginyl-L-arginyl-L-Arginine trifluoroacetic acid. Grades: >98%. Molecular formula: C62H115N27O17S.C2HF3O2. Mole weight: 1656.83. |  |
| carbamate kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:carbamate phosphotransferase. Other names in common use include CKase, carbamoyl phosphokinase, and carbamyl phosphokinase. This enzyme participates in 4 metabolic pathways: purine metabolism, glutamate metabolism, arginine and proline metabolism, and nitrogen metabolism. Group: Enzymes. Synonyms: CKase carbamoyl phosphokinase; carbamyl phosphokinase. Enzyme Commission Number: EC 2.7.2.2. CAS No. 9026-69-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3174; carbamate kinase; EC 2.7.2.2; 9026-69-1; CKase carbamoyl phosphokinase; carbamyl phosphokinase. Cat No: EXWM-3174. | |
| Creatine monohydrate | Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state. Applications: Involved with rapid atp production primarily in skeletal muscle tissue via the action of creatine kinase(s). Group: Coenzymes. Synonyms: N-Amidinosarcosine monohydrate. CAS No. 6020-87-7. Mole weight: 149.15. Form: Solid. N-Amidinosarcosine monohydrate; Creatine monohydrate; 6020-87-7. Cat No: COEC-096. | |
| guanidinoacetate kinase | Guanidinoacetate kinase belongs to the family of transferases, specifically those that transfer phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:guanidinoacetate N-phosphotransferase. This enzyme is also called glycocyamine kinase. This enzyme participates in arginine and proline metabolism. Group: Enzymes. Synonyms: glycocyamine kinase. Enzyme Commission Number: EC 2.7.3.1. CAS No. 9026-60-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3180; guanidinoacetate kinase; EC 2.7.3.1; 9026-60-2; glycocyamine kinase. Cat No: EXWM-3180. | |
| lysine carboxypeptidase | A zinc enzyme found in plasma. Inactivates bradykinin and anaphylatoxins in blood plasma. In peptidase family M14 (carboxypeptidase A family). Group: Enzymes. Synonyms: carboxypeptidase N; arginine carboxypeptidase; kininase I; anaphylatoxin inactivator; plasma carboxypeptidase B; creatine kinase conversion factor; bradykinase; kininase Ia; hippuryllysine hydrolase; bradykinin-decomposing enzyme; protaminase; CPase N; creatinine kinase convertase; peptidyl-L-lysine(-L-arginine) hydrolase; CPN. Enzyme Commission Number: EC 3.4.17.3. CAS No. 9013-89-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4077; lysine carboxypeptidase; EC 3.4.17.3; 9013-89-2; carboxypeptidase N; arginine carboxypeptidase; kininase I; anaphylatoxin inactivator; plasma carboxypeptidase B; creatine kinase conversion factor; bradykinase; kininase Ia; hippuryllysine hydrolase; bradykinin-decomposing enzyme; protaminase; CPase N; creatinine kinase convertase; peptidyl-L-lysine(-L-arginine) hydrolase; CPN. Cat No: EXWM-4077. | |
| ML167 | ML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4. The Cdc2-like kinases (Clk 's) and the dual-specificity tyrosine phosphorylation-regulated kinases (Dyrk 's) have specified roles in gene splicing. Specifically, the Clk class of enzymes has been shown to phosphorylate the serine- and arginine-rich (SR) proteins, which are a major component of the spliceosome. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ML167; ML-167; ML 167; CID 44968231; CID44968231; CID-44968231; NCGC00188654; NCGC-00188654; NCGC 00188654. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1285702-20-6. Molecular formula: C19H17N3O3. Mole weight: 335.36. Purity: >98%. IUPACName: (5-(4-(((5-methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol. Canonical SMILES: OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1. Product ID: ACM1285702206. Alfa Chemistry ISO 9001:2015 Certified. Categories: M167 VADS. |  |
| protein arginine phosphatase | The enzyme, characterized from Gram-positive bacteria, hydrolyses the phosphoramidate (P-N) bond of Nω-phospho-L-arginine residues in proteins and peptides that were phosphorylated by EC 2.7.14.1, protein-arginine-kinase. Group: Enzymes. Synonyms: YwlE. Enzyme Commission Number: EC 3.9.1.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4750; protein arginine phosphatase; EC 3.9.1.2; YwlE. Cat No: EXWM-4750. | |
| R-59-949 | R-59-949 is an inhibitor of diacylglycerol kinase α (DGK-α) expressed in vascular smooth muscle cells. It inhibits inducible nitric oxide production in vascular smooth muscle cells through decreasing transplasmalemmal L-arginine uptake. Synonyms: Diacylglycerol Kinase Inhibitor II; DKGI-II; R 59949; R 59 949. Grades: ≥98%. CAS No. 120166-69-0. Molecular formula: C28H25F2N3OS. Mole weight: 489.6. | |
| Sakamototide substrate peptide acetate | Sakamototide substrate peptide acetate is a substrate peptide of a member of the kinase AMPK family and is used for the determination of kinase activity. Synonyms: H-Ala-Leu-Asn-Arg-Thr-Ser-Ser-Asp-Ser-Ala-Leu-His-Arg-Arg-Arg-OH.CH3CO2H; L-alanyl-L-leucyl-L-asparagyl-L-arginyl-L-threonyl-L-seryl-L-seryl-L-alpha-aspartyl-L-seryl-L-alanyl-L-leucyl-L-histidyl-L-arginyl-L-arginyl-L-arginine acetic acid. Grades: ≥95%. CAS No. 2703746-19-2. Molecular formula: C71H126N30O25. Mole weight: 1799.97. | |
| SAMS | SAMS peptide, a synthetic peptide substrate for AMPK based on the sequence around Ser79 on acetyl-CoA carboxylase, is more selective for the kinase than acetyl CoA carboxylase itself, and provides a convenient and sensitive assay for AMPK. Synonyms: (Ser76, Arg86.87)-ACC-α (73-87) (dephosphorylated) (E.coli, rat); (Ser76, Arg86.87)-Acetyl-CoA Carboxylase 1 (73-87) (dephosphorylated) (E.coli, rat); (Ser77, Arg87.88)-ACC-α (74-88) (dephosphorylated) (bovine, ovine); (Ser77, Arg87.88)-Acetyl-CoA Carboxyla; H-His-Met-Arg-Ser-Ala-Met-Ser-Gly-Leu-His-Leu-Val-Lys-Arg-Arg-OH; L-histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-seryl-glycyl-L-leucyl-L-histidyl-L-leucyl-L-valyl-L-lysyl-L-arginyl-L-arginine. Grades: >95%. CAS No. 125911-68-4. Molecular formula: C74H131N29O18S2. Mole weight: 1779.15. | |
| TC-E 5003 | TC-E 5003 is a selective protein arginine methyltransferase 1 ( PRMT1 ) inhibitor with an IC 50 of 1.5 μM against hPRMT1. TC-E 5003 modulates the lipopolysaccharide (LPS) (HY-D1056)-induced AP-1 and NF-κB signaling pathways with anti-inflammatory properties. TC-E 5003 also upregulates the expression of Ucp1 and Fgf21, activates protein kinase A signaling and lipolysis in primary subcutaneous adipocytes from both mouse and humans. TC-E 5003 is promising for research of obesity and associated metabolic disorders, oxidative stress, inflammation and cancers [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 17328-16-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-107574. |  |
| ZIP acetate | ZIP acetate is a cell-permeable inhibitor of protein kinase Mζ (PKMζ), which is a constitutively active and atypical PKC isozyme involved in LTP maintenance. ZIP selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. ZIP reverses late-phase LTP (IC50 = 1-2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. Synonyms: myristoyl-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg-OH.CH3CO2H; N-myristoyl-L-arginyl-L-leucyl-L-tyrosyl-L-arginyl-L-lysyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-L-seryl-L-alanyl-glycyl-L-arginine acetic acid; N-(1-Oxotetradecyl)-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucine acetate; Peptide ZIP acetate; z-Pseudosubstrate inhibitory peptide acetate. Grades: ≥94%. Molecular formula: C92H158N30O19. Mole weight: 1988.43. | |
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