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| Product | Description | |
|---|---|---|
| aromatase | A cytochrome P-450. The enzyme catalyses three sequential hydroxylations of the androgens androst-4-ene-3,17-dione and testosterone, resulting in their aromatization and forming the estrogens estrone and 17β-estradiol, respectively. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: CYP19A1 (gene name); estrogen synthetase (incorrect). Enzyme Commission Number: EC 1.14.14.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0911; aromatase; EC 1.14.14.14; CYP19A1 (gene name); estrogen synthetase (incorrect). Cat No: EXWM-0911. |  |
| Aromatase-IN-2 | Aromatase-IN-2 is a potent aromatase inhibitor with an IC 50 value of 1.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121768-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148430. |  |
| Anti-Aromatase/CYP19A1 antibody produced in goat | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Nonsteroidal aromatase inhibitor 1 | Nonsteroidal aromatase inhibitor 1 (Compound 13h) is a nonsteroidal aromatase ( CYP19A1 ) inhibitor ( IC 50 =0.09 nM). Nonsteroidal aromatase inhibitor 1 has potential for breast cancer research [1]. Nonsteroidal aromatase inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033282-93-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150775. | |
| (11β,16α)-11,16-Dihydroxyandrosta-1,4-diene-3,17-dione | (11β,16α)-11,16-Dihydroxyandrosta-1,4-diene-3,17-dione is a highly potent pharmaceutical compound exhibiting its efficacy in the research of diverse hormone-responsive malignancies. By suppressing the enzymatic activity of aromatase, this remarkable substance successfully diminishes estrogen synthesis, thereby impeding the progression of estrogen-reliant tumors. Its wide-ranging applications in studying breast cancer, endometriosis and prostate cancer render it an indispensable agent in the biomedical sector, facilitating the advancement of tailored interventions against hormonally mediated afflictions. Synonyms: Androsta-1,4-diene-3,17-dione, 11,16-dihydroxy-, (11β,16α)-; (8S,9S,10R,11S,13S,14S,16R)-11,16-dihydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione; 1,4-Androstadien-11-beta-16-alpha-Diol-3,17-Dione. Grade: ≥95%. CAS No. 910299-74-0. Molecular formula: C19H24O4. Mole weight: 316.39. |  |
| 1,2-α-Epoxy Exemestane | 1,2-α-Epoxy Exemestane is a metabolite of Exemestane (E957000); a third-generation steroidal aromatase inhibitor that has been used in clinics for hormone-dependent breast cancer treatment in post-menopausal women. Group: Biochemicals. Grades: Highly Purified. CAS No. 159354-61-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H24O3, Molecular Weight: 312.399999999999. US Biological Life Sciences. |  Worldwide |
| 16α,17α-Epoxy Exemestane | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16α,17α-Epoxy-6-methyleneandrosta-1,4-diene-3-one. Grade: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
| 17-beta-Hydroxy Exemestane | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane; (17β)-17-Hydroxy-6-methyleneandrosta-1,4-dien-3-one; Methylene Boldenone. Grade: > 95%. CAS No. 122370-91-6. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| 17-beta-Hydroxy Exemestane Epoxide | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Oxirane Boldenone; (6α,17β)- 17-Hydroxyspiro[androsta-1,4-diene-6,2'-oxiran]-3-one; 17β-Hydroxy-6α-spiro[androsta-1,4-diene-6,2'-oxiran]-3-one. Grade: > 95%. CAS No. 1331732-05-8. Molecular formula: C20H26O3. Mole weight: 314.43. | |
| 19-Hydroxyandrostendione | A novel substituted estrogen as aromatase inhibitor. Group: Biochemicals. Alternative Names: 19-Hydroxyandrost-4-ene-3,17-dione; Androst-4-en-19-ol-3,17-dione; Androst-4-ene-3,17-dione-19-ol; NSC 74233. Grades: Highly Purified. CAS No. 510-64-5. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C19H26O3, Molecular Weight: 302.41. US Biological Life Sciences. | Worldwide |
| 19-Hydroxy Androstendione-[19-d2] | 19-Hydroxy Androstendione-[19-d2] is a novel labelled substituted estrogen as an aromatase inhibitor. Uses: A novel labelled substituted estrogen as aromatase inhibitor. Synonyms: 19-Hydroxyandrost-4-ene-3,17-dione-19,19-d2; Androst-4-en-19-ol-3,17-dione-d2; Androst-4-ene-3,17-dione-19-ol-d2; NSC 74233-d2. Grade: 95%. CAS No. 71995-64-7. Molecular formula: C19H24D2O3. Mole weight: 304.42. | |
| 19-Hydroxy Androstendione-19-d2 | A novel labeled substituted estrogen as aromatase inhibitor. Group: Biochemicals. Alternative Names: 19-Hydroxyandrost-4-ene-3,17-dione-19,19-d2; Androst-4-en-19-ol-3,17-dione-d2; Androst-4-ene-3,17-dione-19-ol-d2; NSC 74233-d2. Grades: Highly Purified. CAS No. 71995-64-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1-Benzylimidazole | Benzylimidazole is an inducer of various cytochrome P-450 isozymes and inhibitor of thromboxane A2 synthase. A potential aromatase inhibitor. Uses: Benzylimidazole is an inducer of various cytochrome p-450 isozymes and inhibitor of thromboxane a2 synthase. a potential aromatase inhibitor. Synonyms: 1-(phenylmethyl)imidazole; 1-benzylimidazole. Grade: ≥ 99 %. CAS No. 4238-71-5. Molecular formula: C10H10N2. Mole weight: 158.20. | |
| 1-(Phenylmethyl)-1H-indole-3-methanol | 1-(Phenylmethyl)-1H-indole-3-methanol is used as a reactant in dearomative indole (3 + 2) cycloaddition reactions. It is used to synthesize inhibitors of P450 aromatase. Group: Biochemicals. Grades: Highly Purified. CAS No. 60941-76-6. Pack Sizes: 250mg, 1g. Molecular Formula: C16H15NO, Molecular Weight: 237.3. US Biological Life Sciences. | Worldwide |
| 20α-Dihydroprogesterone | 20α-Dihydroprogesterone is the metabolite of Progesterone (HY-N0437). 20α-Dihydroprogesterone inhibits cell proliferation and migration in breast tissue. 20α-Dihydroprogesterone inhibits aromatase in cell MCF-7aro with IC 50 about 5 μM [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 20-OH-P. CAS No. 145-14-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113062. | |
| 2-Decyn-1-ol | 2-Decyn-1-ol is used in the synthesis of antitumor agents, isomers of Panaxytriol and Falcarinol (F101100). Also used in the synthesis of aromatase inhibitors used in the treatment of cancers, primarily breast and ovarian. Group: Biochemicals. Grades: Highly Purified. CAS No. 4117-14-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-4-hydroxybenzenemethanol | 2-Fluoro-4-hydroxybenzenemethanol is a reactant used in the synthesis of cyanophenyl (triazolyl) aminomethylphenyl sulfamates as dual aromatase-sulfatase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 96740-92-0. Pack Sizes: 1g, 10g. Molecular Formula: C7H7FO2, Molecular Weight: 142.13. US Biological Life Sciences. | Worldwide |
| 2-Hydroxyestradiol 3-O-b-D-glucuronide | 2-Hydroxyestradiol 3-O-b-D-glucuronide is a compound used in the research of estrogen-dependent breast cancer. It acts as an inhibitor of aromatase enzyme, reducing the compoundion of estrogen. With its glucuronide structure, it enhances the solubility and excretion of the active compound, improving its efficacy. CAS No. 55666-09-6. Molecular formula: C24H32O9. Mole weight: 464.51. | |
| 2-Methylbenzophenone | 2-Methylbenzophenone is an intermediate used to prepare imidazolyl methyl benzophenones as aromatase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 131-58-8. Pack Sizes: 1g, 5g. Molecular Formula: C14H12O. US Biological Life Sciences. | Worldwide |
| 2-Methylestrone | 2-Methylestrone is an estrogen analog and aromatase inhibitor that has been shown to be clinically useful in the treatment of estrogen-dependent breast cancer. 2-Methylestrone may also have neuroprotective effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 2626-12-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H24O2, Molecular Weight: 284.39. US Biological Life Sciences. | Worldwide |
| 4,5-Epoxy-17 β-hydroxy-5-androstan-3-one | 4,5-Epoxy-17 β-hydroxy-5-androstan-3-one is used in the preparation of steroidal carbonitriles as potential aromatase inhibitors. 4α,5-Epoxy-17 β-hydroxy-5α-androstan-3-one inhibits HIV-1 nuclear regulatory protein tat. Group: Biochemicals. Alternative Names: (17 β)-4,5-Epoxy-17-hydroxy-androstan-3-one. Grades: Highly Purified. CAS No. 51154-10-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (4α,?5α)?-Formestane | (4α,?5α)?-Formestane is an isomer of Formestane. Formestane is a type I, steroidal, selective aromatase inhibitor that is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. Formestane is an analogue of androstenedione. It is also used to inhibit the estrogen production. Synonyms: 4-Hydroxyandrostane-3,17-dione; 4-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione. CAS No. 848-35-1. Molecular formula: C19H28O3. Mole weight: 304.43. | |
| 4-(Dibromomethyl)benzonitrile | An impurity of Letrozole. Letrozole is a nonsteroidal aromatase inhibitor primarily used to treat hormone receptor-positive breast cancer in postmenopausal women. Synonyms: p-(Dibromomethyl)benzonitrile; p-Cyanobenzal bromide; Letrozole Impurity 50; 4-Cyanobenzylidene bromide. Grade: ≥95%. CAS No. 67013-55-2. Molecular formula: C8H5Br2N. Mole weight: 274.94. | |
| 6α-Bromo Androstenedione | Androstenedione analog, an aromatase inhibitor. Group: Biochemicals. Alternative Names: (6α)-6-Bromoandrost-4-ene-3,17-dione. Grades: Highly Purified. CAS No. 61145-67-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 6 β-Bromo Androstenedione | Androstenedione analog, an aromatase inhibitor. Group: Biochemicals. Alternative Names: (6 β)-6-Bromoandrost-4-ene-3,17-dione. Grades: Highly Purified. CAS No. 38632-00-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 6-Methyleneandrost-4-ene-3,17-dione-19-d3 | Exemestane intermediate. A new irreversible aromatase inhibitor. Group: Biochemicals. Alternative Names: 6-Methyleneandrost-4-en-3,17-dione-19-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 7-Hydroxyflavanone | 7-Hydroxyflavanone is a potent inhibitor of aromatase ( CYP19 ) activity with the IC 50 of 65 μM. 7-Hydroxyflavanone exerts various biological effects, including anticarcinogenic, antioxidant and (anti-)estrogenic effects, and modula. Uses: Scientific research. Group: Natural products. CAS No. 6515-36-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W087008. | |
| (8R,9S,10R,13S,14S)-10,13-Dimethyl-7,8,9,11,12,13,15,16-octahydro-10H-cyclopenta[a]phenanthrene-3,6,17(14H)-trione | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Uses: A derivative of exemestane (e957000), a new aromatase inhibitor. Synonyms: (8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,6,17-trione; (8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,6,17-trione. Grade: > 95 %. CAS No. 72648-46-5. Molecular formula: C19H22O3. Mole weight: 298.38. | |
| a,a,aÂ’,aÂ’-Tetra-(methyl-d3)-5-bromomethyl-1,3-benzenediacetonitrile | A labeled intermediate in the synthesis of Anastrozole, an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| a,a,aÂ’,aÂ’-Tetra-(methyl-d3)-5-methyl-1,3-benzenediacetonitrile | A labeled intermediate in the synthesis of Anastrozole, an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| α, α, αÂ’, αÂ’-Tetramethyl-5-methyl-1, 3-benzenediacetonitrile | An intermediate in the synthesis of Anastrozole , an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 120511-72-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Alpha-Naphthoflavone | Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b> IC < sub> 50 < / sub> < / b> and < b> K < sub> I < / sub> < / b> value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 604-59-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-125833. | |
| α-Naphthylflavone | α-Naphthylflavone is a flavenoid compound that acts on μ-opioid receptors in the treatment of pain. Also acts as a non-steroidal aromatase inhibitor used in breast cancer therapy. Group: Biochemicals. Alternative Names: 7,8-Benzoflavone; ANF; Benzo[h]flavone; NSC 407011; UCCF 023; α-Naphthoflavone. Grades: Highly Purified. CAS No. 604-59-1. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C19H12O2, Molecular Weight: 272.3. US Biological Life Sciences. | Worldwide |
| Aminoglutethimide | Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DL-Aminoglutethimide. CAS No. 125-84-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0237. | |
| Aminoglutethimide (3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione) | An aromatase inhibitor. Also blocks adrenal steroidogenesis. Group: Biochemicals. Alternative Names: 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Anastrozole | Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC 50 of 15 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD1033. CAS No. 120511-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14274. | |
| Anastrozole-d12 | Labelled Anastrozole, an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Anastrozole (ZD-1033, ICI-D-1033, Arimidex) | An aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Alternative Names: ZD-1033, ICI-D-1033, Arimidex. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Androst-4-ene-3,6,17-trione | An aromatase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 2243-6-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Androst-4-ene-3,6,17-trione (4-Androsten-3, 6, 17-trione) | An aromatase inhibitor. Group: Biochemicals. Alternative Names: 4-Androsten-3, 6, 17-trione. Grades: Purified. CAS No. 2243-6-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Atamestane | Atamestane is a synthetic steroidal substance with antineoplastic activity. Atamestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Uses: Enzyme inhibitors. Synonyms: Atamestanum; Atamestano; Biomed-777; Biomed 777; Biomed777; CCRIS 6528; CCRIS6528; CCRIS-6528; SH-489; SH 489; SH489. CAS No. 96301-34-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| BBT594 | BBT594, also called as NVP-BBT594, a dihydroindole compound, originally developed as an inhibitor of wild-type and T315I-mutant BCR-ABL1, and then subsequently was shown to inhibit JAK2 activity (IC50 = 8nM ~ 29nM in murine models). The Type II JAK2 inhibitor NVP-BBT594 also displayed potent inhibition of HCV activity (EC50 < 1.5 mM). BBT594 impairs GDNF-RET signaling, a promising therapeutic target to enhance the sensitivity to aromatase inhibitor (AI) treatment and revert AI resistance in ER+ breast cancer cells. It also impairs GDNF-dependent growth of MCF7-LTED cells. Synonyms: 5-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2,3-dihydroindole-1-carboxamide; BBT-594; BBT-594; BBT-594; NVP-BBT594; NVP BBT594; NVP BBT-594GTPL7584; SCHEMBL12972358; 5-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2,3-dihydroindole-1-carboxamide. CAS No. 882405-89-2. Molecular formula: C28H30F3N7O3. Mole weight: 569.59. | |
| Cgp 45688 | Cgp 45688 is an non-steroidal aromatase inhibitor originated byNovartis. It has anti-tumor effects, but no development for treatment of cancer was reported. Uses: Cancer. Synonyms: Cgp 45688; Cgp45688; Cgp-45688. 4,4'-(2H-tetrazol-2-ylmethylene)bis-Benzonitrile. Grade: 98%. CAS No. 134520-88-0. Molecular formula: C16H10N6. Mole weight: 286.30. | |
| Cgp 47645 | Cgp 47645 is non-steroidal aromatase inhibitor with anti-tumor and endocrine effects. It is orally active. Uses: Anti-tumor. Synonyms: Cgp 47645; Cgp47645; Cgp-47645; Leflutrozole; UNII-RCX0IE6EJZ; 4,4'-(fluoro-1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile. Grade: 98%. CAS No. 143030-47-1. Molecular formula: C17H10FN5. Mole weight: 303.30. | |
| Dexfadrostat | Dexfadrostat ((R)-Fadrozole) is a potent nonsteroidal inhibitor [1]. Dexfadrostat also inhibits human placental aromatase (pIC 50 = 6.17) and aldosterone biosynthesis. Dexfadrostat reverses cardiac fibrosis in spontaneously hypertensive heart failure rats. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Fadrozole; (R)-CGS 16949A free base; FAD286. CAS No. 102676-87-9. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-113986. | |
| Dienogest | Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2 , mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE 2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STS 557. CAS No. 65928-58-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0084. | |
| Endoxifen | Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 110025-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18719E. | |
| Endoxifen hydrochloride | Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen hydrochloride has the potential for breast cancer study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1197194-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18719B. | |
| Enilconazole | Imazalil is an antifungal agent that may have carcinogenic potential. Imazalil also inhibits androgen receptors and aromatase through a mixed competitive/noncompetitive mode in vitro. Synonyms: Imazalil; Deccozil; Bromazil; Fungaflor; Clinafarm; Chloramizol; Fungazil; Magnate; 1-(2-(Allyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole; 1-[2-(Allyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole. CAS No. 35554-44-0. Molecular formula: C14H14Cl2N2O. Mole weight: 297.18. | |
| Epoxy Exemestane (6-Alfa Isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione. Grade: > 95%. CAS No. 152764-24-4. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Epoxy Exemestane (6-Beta Isomer) | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione. Grade: > 95%. CAS No. 152764-31-3. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Eriodictyol chalcone | Eriodictyol chalcone possesses both anti-aromatase and anti-17β-HSD activity. Synonyms: 2',3,4,4',6'-Pentahydroxychalcone; 3,4,2',4',6'-Pentahydroxychalcone. CAS No. 14917-41-0. Molecular formula: C15H12O6. Mole weight: 288.25. | |
| Estrone | Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of estrone in premenopausal women fluctuate according to the menstral cycle and becomes the most predominant estrogen in postmenopausal women. The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol. Synonyms: 3-Hydroxyestra-1,3,5(10)-trien-17-one; (+)-Estrone; 1,3,5(10)-Estratrien-3-ol-17-one; 3-Hydroxy-17-keto-estra-1,3,5-triene; Aquacrine; Crinovaryl; Cristallovar; Crystogen; WAY 164397; Wynestron. Grade: 0.95. CAS No. 53-16-7. Molecular formula: C18H22O2. Mole weight: 270.372. | |
| Eurycomanone | Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. Uses: Scientific research. Group: Natural products. Alternative Names: Pasakbumin A. CAS No. 84633-29-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N5012. | |
| Exemestane | Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304; EXE. CAS No. 107868-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13632. | |
| Exemestane-d3 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d3. Molecular formula: C20H21O2D3. Mole weight: 299.43. | |
| Exemestane-d5 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d5. Molecular formula: C20H19O2D5. Mole weight: 301.44. | |
| Exemestane Impurity 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-α-Epoxy Exemestane; (1α,2α)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione. Grade: > 95%. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Impurity 3 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6,16-Dimethylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H24O2. Mole weight: 308.42. | |
| Exemestane Impurity 4 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16-methylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
| Exemestane Metabolite 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grade: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51. | |
| Exemestane Metabolite 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45. | |
| Exemestane Related Compound | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.46. | |
| Exemestane Related Compound 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-(Formyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-alpha isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-alpha-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-beta isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-beta-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound A | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-Dihydro Exemestane; 6-Methyleneandrost-4-ene-3,17-dione; 6-Methyleneandrost-4-en-3,17-dione. Grade: > 95%. CAS No. 19457-55-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| Exemestane Related Compound B | Isotope labelled Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: Androsta-1,4-diene-3,17-dione, 6-(hydroxymethyl). Grade: > 95%. CAS No. 184972-09-6. Molecular formula: C20H26O3. Mole weight: 314.43. | |
| Exemestane (Standard) | Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304(Standard); EXE (Standard). CAS No. 107868-30-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13632R. | |
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