Aromatase Suppliers USA
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Product | Description | |
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1,2-α-Epoxy Exemestane Quick inquiry Where to buy Suppliers range | 1,2-α-Epoxy Exemestane is a metabolite of Exemestane (E957000); a third-generation steroidal aromatase inhibitor that has been used in clinics for hormone-dependent breast cancer treatment in post-menopausal women. Group: Biochemicals. Grades: Highly Purified. CAS No. 159354-61-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H24O3, Molecular Weight: 312.399999999999. US Biological Life Sciences. | Worldwide |
16α,17α-Epoxy Exemestane Quick inquiry Where to buy Suppliers range | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16α,17α-Epoxy-6-methyleneandrosta-1,4-diene-3-one. Grades: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
17-beta-Hydroxy Exemestane Quick inquiry Where to buy Suppliers range | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane; (17β)-17-Hydroxy-6-methyleneandrosta-1,4-dien-3-one; Methylene Boldenone. Grades: > 95%. CAS No. 122370-91-6. Molecular formula: C20H26O2. Mole weight: 298.43. | |
17-beta-Hydroxy Exemestane Epoxide Quick inquiry Where to buy Suppliers range | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Oxirane Boldenone; (6α,17β)- 17-Hydroxyspiro[androsta-1,4-diene-6,2'-oxiran]-3-one; 17β-Hydroxy-6α-spiro[androsta-1,4-diene-6,2'-oxiran]-3-one. Grades: > 95%. CAS No. 1331732-05-8. Molecular formula: C20H26O3. Mole weight: 314.43. | |
19-Hydroxyandrostendione Quick inquiry Where to buy Suppliers range | A novel substituted estrogen as aromatase inhibitor. Group: Biochemicals. Alternative Names: 19-Hydroxyandrost-4-ene-3,17-dione; Androst-4-en-19-ol-3,17-dione; Androst-4-ene-3,17-dione-19-ol; NSC 74233. Grades: Highly Purified. CAS No. 510-64-5. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C19H26O3, Molecular Weight: 302.41. US Biological Life Sciences. | Worldwide |
19-Hydroxy Androstendione-19-d2 Quick inquiry Where to buy Suppliers range | A novel labeled substituted estrogen as aromatase inhibitor. Group: Biochemicals. Alternative Names: 19-Hydroxyandrost-4-ene-3,17-dione-19,19-d2; Androst-4-en-19-ol-3,17-dione-d2; Androst-4-ene-3,17-dione-19-ol-d2; NSC 74233-d2. Grades: Highly Purified. CAS No. 71995-64-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
1-(Phenylmethyl)-1H-indole-3-methanol Quick inquiry Where to buy Suppliers range | 1-(Phenylmethyl)-1H-indole-3-methanol is used as a reactant in dearomative indole (3 + 2) cycloaddition reactions. It is used to synthesize inhibitors of P450 aromatase. Group: Biochemicals. Grades: Highly Purified. CAS No. 60941-76-6. Pack Sizes: 250mg, 1g. Molecular Formula: C16H15NO, Molecular Weight: 237.3. US Biological Life Sciences. | Worldwide |
2-Decyn-1-ol Quick inquiry Where to buy Suppliers range | 2-Decyn-1-ol is used in the synthesis of antitumor agents, isomers of Panaxytriol and Falcarinol (F101100). Also used in the synthesis of aromatase inhibitors used in the treatment of cancers, primarily breast and ovarian. Group: Biochemicals. Grades: Highly Purified. CAS No. 4117-14-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
2-Fluoro-4-hydroxybenzenemethanol Quick inquiry Where to buy Suppliers range | 2-Fluoro-4-hydroxybenzenemethanol is a reactant used in the synthesis of cyanophenyl (triazolyl) aminomethylphenyl sulfamates as dual aromatase-sulfatase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 96740-92-0. Pack Sizes: 1g, 10g. Molecular Formula: C7H7FO2, Molecular Weight: 142.13. US Biological Life Sciences. | Worldwide |
2-Hydroxyestradiol 3-O-b-D-glucuronide Quick inquiry Where to buy Suppliers range | 2-Hydroxyestradiol 3-O-b-D-glucuronide is a compound compound used in the reserch of estrogen-dependent breast cancer. It acting as an inhibitor of aromatase enzyme, reducing the compoundion of estrogen. With its glucuronide structure, it enhances the solubility and excretion of the active compound, improving its efficacy. CAS No. 55666-09-6. Molecular formula: C24H32O9. Mole weight: 464.51. | |
2-Methylbenzophenone Quick inquiry Where to buy Suppliers range | 2-Methylbenzophenone is an intermediate used to prepare imidazolyl methyl benzophenones as aromatase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 131-58-8. Pack Sizes: 1g, 5g. Molecular Formula: C14H12O. US Biological Life Sciences. | Worldwide |
2-Methylestrone Quick inquiry Where to buy Suppliers range | 2-Methylestrone is an estrogen analog and aromatase inhibitor that has been shown to be clinically useful in the treatment of estrogen-dependent breast cancer. 2-Methylestrone may also have neuroprotective effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 2626-12-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H24O2, Molecular Weight: 284.39. US Biological Life Sciences. | Worldwide |
4,5-Epoxy-17 β-hydroxy-5-androstan-3-one Quick inquiry Where to buy Suppliers range | 4,5-Epoxy-17 β-hydroxy-5-androstan-3-one is used in the preparation of steroidal carbonitriles as potential aromatase inhibitors. 4α,5-Epoxy-17 β-hydroxy-5α-androstan-3-one inhibits HIV-1 nuclear regulatory protein tat. Group: Biochemicals. Alternative Names: (17 β)-4,5-Epoxy-17-hydroxy-androstan-3-one. Grades: Highly Purified. CAS No. 51154-10-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
(4α,?5α)?-Formestane Quick inquiry Where to buy Suppliers range | (4α,?5α)?-Formestane is an isomer of Formestane. Formestane is a type I, steroidal, selective aromatase inhibitor that is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. Formestane is an analogue of androstenedione. It is also used to inhibit the estrogen production. Synonyms: 4-Hydroxyandrostane-3,17-dione; 4-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione. CAS No. 848-35-1. Molecular formula: C19H28O3. Mole weight: 304.43. | |
6α-Bromo Androstenedione Quick inquiry Where to buy Suppliers range | Androstenedione analog, an aromatase inhibitor. Group: Biochemicals. Alternative Names: (6α)-6-Bromoandrost-4-ene-3,17-dione. Grades: Highly Purified. CAS No. 61145-67-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
6 β-Bromo Androstenedione Quick inquiry Where to buy Suppliers range | Androstenedione analog, an aromatase inhibitor. Group: Biochemicals. Alternative Names: (6 β)-6-Bromoandrost-4-ene-3,17-dione. Grades: Highly Purified. CAS No. 38632-00-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
6-Methyleneandrost-4-ene-3,17-dione-19-d3 Quick inquiry Where to buy Suppliers range | Exemestane intermediate. A new irreversible aromatase inhibitor. Group: Biochemicals. Alternative Names: 6-Methyleneandrost-4-en-3,17-dione-19-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
(8R,9S,10R,13S,14S)-10,13-Dimethyl-7,8,9,11,12,13,15,16-octahydro-10H-cyclopenta[a]phenanthrene-3,6,17(14H)-trione Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Uses: A derivative of exemestane (e957000), a new aromatase inhibitor. Synonyms: (8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,6,17-trione; (8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,6,17-trione. Grades: > 95 %. CAS No. 72648-46-5. Molecular formula: C19H22O3. Mole weight: 298.38. | |
a,a,a,a-Tetra-(methyl-d3)-5-bromomethyl-1,3-benzenediacetonitrile Quick inquiry Where to buy Suppliers range | A labeled intermediate in the synthesis of Anastrozole, an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
a,a,a,a-Tetra-(methyl-d3)-5-methyl-1,3-benzenediacetonitrile Quick inquiry Where to buy Suppliers range | A labeled intermediate in the synthesis of Anastrozole, an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
α, α, α, α-Tetramethyl-5-methyl-1, 3-benzenediacetonitrile Quick inquiry Where to buy Suppliers range | An intermediate in the synthesis of Anastrozole , an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 120511-72-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
α-Naphthylflavone Quick inquiry Where to buy Suppliers range | α-Naphthylflavone is a flavenoid compound that acts on μ-opioid receptors in the treatment of pain. Also acts as a non-steroidal aromatase inhibitor used in breast cancer therapy. Group: Biochemicals. Alternative Names: 7,8-Benzoflavone; ANF; Benzo[h]flavone; NSC 407011; UCCF 023; α-Naphthoflavone. Grades: Highly Purified. CAS No. 604-59-1. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C19H12O2, Molecular Weight: 272.3. US Biological Life Sciences. | Worldwide |
Aminoglutethimide (3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione) Quick inquiry Where to buy Suppliers range | An aromatase inhibitor. Also blocks adrenal steroidogenesis. Group: Biochemicals. Alternative Names: 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Anabasine hydrochloride Quick inquiry Where to buy Suppliers range | Anabasine is a natural, nicotine-related alkaloid, which is first isolated from plants of the genus Nicotiana. Anabasine binds the same receptor as nicotine, the nicotinic acetylcholine α4β2 subtype with Ki of 38 nM and increases nicotine-induced hyperactivity, sensitization, and intravenous self-administration. Anabasine inhibits aromatase and nicotinic acetylcholine receptors (nAChRs) and may produce a depolarizing neuromuscular junction (NMJ) block. Anabasine can also be used as a clinical biomarker for tobacco smoke exposure. Additionally, anabasine is teratogenic and may be used as an insecticide. Synonyms: (S)-3-(2-piperidinyl)-pyridine hydrochloride; 3-(2S)-2-Piperidinyl-pyridine hydrochloride. Grades: ≥95%. CAS No. 15251-47-5. Molecular formula: C10H14N2·xHCl. Mole weight: 162.2. | |
Anastrozole Quick inquiry Where to buy Suppliers range | Anastrozole is a nonsteroidal aromatase inhibitor that works by decreasing the amount of estrogen the body makes. Anastrozole is approved for the treatment of breast cancer in postmenopausal women. Synonyms: Arimidex; anastrazole; Anastrozol. CAS No. 120511-73-1. Molecular formula: C17H19N5. Mole weight: 293.4. | |
Anastrozole-d12 Quick inquiry Where to buy Suppliers range | Labelled Anastrozole, an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Anastrozole (ZD-1033, ICI-D-1033, Arimidex) Quick inquiry Where to buy Suppliers range | An aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Alternative Names: ZD-1033, ICI-D-1033, Arimidex. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Androst-4-ene-3,6,17-trione Quick inquiry Where to buy Suppliers range | An aromatase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 2243-6-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Androst-4-ene-3,6,17-trione (4-Androsten-3, 6, 17-trione) Quick inquiry Where to buy Suppliers range | An aromatase inhibitor. Group: Biochemicals. Alternative Names: 4-Androsten-3, 6, 17-trione. Grades: Purified. CAS No. 2243-6-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Atamestane Quick inquiry Where to buy Suppliers range | Atamestane is a synthetic steroidal substance with antineoplastic activity. Atamestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Uses: Enzyme inhibitors. Synonyms: Atamestanum; Atamestano; Biomed-777; Biomed 777; Biomed777; CCRIS 6528; CCRIS6528; CCRIS-6528; SH-489; SH 489; SH489. CAS No. 96301-34-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
BBT594 Quick inquiry Where to buy Suppliers range | BBT594, also called as NVP-BBT594, a dihydroindole compound, originally developed as an inhibitor of wild-type and T315I-mutant BCR-ABL1, and then subsequently was shown to inhibit JAK2 activity (IC50 = 8nM ~ 29nM in murine models). The Type II JAK2 inhibitor NVP-BBT594 also displayed potent inhibition of HCV activity (EC50 < 1.5 mM). BBT594 impairs GDNF-RET signaling, a promising therapeutic target to enhance the sensitivity to aromatase inhibitor (AI) treatment and revert AI resistance in ER+ breast cancer cells. It also impairs GDNF-dependent growth of MCF7-LTED cells. Synonyms: 5-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2,3-dihydroindole-1-carboxamide; BBT-594; BBT-594; BBT-594; NVP-BBT594; NVP BBT594; NVP BBT-594GTPL7584; SCHEMBL12972358; 5-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2,3-dihydroindole-1-carboxamide. CAS No. 882405-89-2. Molecular formula: C28H30F3N7O3. Mole weight: 569.59. | |
(-)-Catechin gallate Quick inquiry Where to buy Suppliers range | (-)-Catechin gallate, a minor polyphenolic constituent in green tea, is used to study its cytotoxicity. It enhances Fe(2+)-induced, lipid peroxidation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cancer. Uses: (-)-catechin gallate has been found to be probably effective in restraining tyrosine phosphorylation caused by vegf and have potential activity in the study of breast cancer. Synonyms: (-)-CG; (-)-Catechin gallate; (2S,3R)-2-(3,4-Dihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol; 3,4,5-Trihydroxybenzoic acid [[(2S)-2β-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran]-3α-yl] ester. Grades: >98%. CAS No. 130405-40-2. Molecular formula: C22H18O10. Mole weight: 442.37. | |
Cgp 45688 Quick inquiry Where to buy Suppliers range | Cgp 45688 is an non-steroidal aromatase inhibitor originated byNovartis. It has anti-tumor effects, but no development for treatment of cancer was reported. Uses: Cancer. Synonyms: Cgp 45688; Cgp45688; Cgp-45688. 4,4'-(2H-tetrazol-2-ylmethylene)bis-Benzonitrile. Grades: 98%. CAS No. 134520-88-0. Molecular formula: C16H10N6. Mole weight: 286.30. | |
Cgp 47645 Quick inquiry Where to buy Suppliers range | Cgp 47645 is non-steroidal aromatase inhibitor with anti-tumor and endocrine effects. It is orally active. Uses: Anti-tumor. Synonyms: Cgp 47645; Cgp47645; Cgp-47645; Leflutrozole; UNII-RCX0IE6EJZ;4,4'-(fluoro-1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile. Grades: 98%. CAS No. 143030-47-1. Molecular formula: C17H10FN5. Mole weight: 303.30. | |
Epoxy Exemestane (6-Alfa Isomer) Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione. Grades: > 95%. CAS No. 152764-24-4. Molecular formula: C20H24O3. Mole weight: 312.41. | |
Epoxy Exemestane (6-Beta Isomer) Quick inquiry Where to buy Suppliers range | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione. Grades: > 95%. CAS No. 152764-31-3. Molecular formula: C20H24O3. Mole weight: 312.41. | |
Exemestane Impurity 1 Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-α-Epoxy Exemestane; (1α,2α)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione. Grades: > 95%. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. | |
Exemestane Impurity 3 Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6,16-Dimethylideneandrosta-1,4-diene-3,17-dione. Grades: > 95%. Molecular formula: C21H24O2. Mole weight: 308.42. | |
Exemestane Impurity 4 Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16-methylideneandrosta-1,4-diene-3,17-dione. Grades: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
Exemestane Metabolite 1 Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grades: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51. | |
Exemestane Metabolite 2 Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grades: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45. | |
Exemestane Related Compound Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione. Grades: > 95%. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.46. | |
Exemestane Related Compound 1 Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-(Formyl)androsta-1,4-dien-3,17-dione. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
Exemestane Related Compound 2 Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
Exemestane Related Compound 2 (17-alpha isomer) Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-alpha-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
Exemestane Related Compound 2 (17-beta isomer) Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-beta-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
Exemestane Related Compound A Quick inquiry Where to buy Suppliers range | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-Dihydro Exemestane; 6-Methyleneandrost-4-ene-3,17-dione; 6-Methyleneandrost-4-en-3,17-dione. Grades: > 95%. CAS No. 19457-55-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
Exemestane Related Compound B Quick inquiry Where to buy Suppliers range | Isotope labelled Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: Androsta-1,4-diene-3,17-dione, 6-(hydroxymethyl). Grades: > 95%. CAS No. 184972-09-6. Molecular formula: C20H26O3. Mole weight: 314.43. | |
Fadrozole Quick inquiry Where to buy Suppliers range | Fadrozole is a potent and selective inhibitor of aromatase with IC50 of 4.5 nM. Uses: Antineoplastic agents, hormonal. Synonyms: Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-; CGS 16949A (free base); 5-p-cyanophenyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine; 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile. Grades: 95%. CAS No. 102676-47-1. Molecular formula: C14H13N3. Mole weight: 223.27. | |
FORMESTANE Quick inquiry Where to buy Suppliers range | formestane, 566-48-3, 4-Hydroxyandrost-4-ene-3,17-dione, 4-Hydroxyandrostenedione, Lentaron, CGP-32349, Lentaron(R), NSC 282175, 4-OH-A, CGP 32349, ANDROST-4-ENE-3,17-DIONE, 4-HYDROXY-, B, Aromatase inhibitor, 4-Hydroxy-4-androstene-3,17-dione, 4-OHA, Formestane [INN:BAN], CCRIS 7483, 4-OHAD, NSC-282175, 4-Hydroxy-delta(sub 4)-androstenedione, BRN 1889793, UNII-PUB9T8T355, 4-oh-androstene-3,17-dione, MLS000028826, MLS002153359, PUB9T8T355, (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione, DTXSID3034113, CHEBI:75172, 4-hydroxy-Delta(4)-androstenedione, Formestane (INN), SMR000058722, FORMESTANE [INN], 17-dione, DTXCID1014113, (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione, CAS-566-48-3, formestano, formestanum, SaveCream, Lentaron Depot, 4-hydroxyandrostene-3,17-dione, Formestane, solid, NCGC00015070-04, NCGC00164380-02, Lentaron (TN), CGP 32 349, Lentaron(R)17-dione, FORMESTANE [MI], Opera_ID_865, Formestane [BAN:INN], D0B6PZ, FORMESTANE [MART.], FORMESTANE [WHO-DD], SCHEMBL25717, MLS001148070, Androst-4-ene-3, 4-hydroxy-, 4-hydroxy-Delta4-androstenedione, BDBM225704, CS333, HMS2090I22, HMS2234J06, HMS3715G16, BCP03066, HY-B0697, Tox21_112111, Tox21_113509, Tox21_302286, NSC282175, s2208, AKOS015895451, Tox21_112111_1, CCG-221077, DB08905, NCGC00164380-01, NCGC00255321-01, NCGC00344560-01, AS-75658, LS-19455, NCI60_002316, D07260, AB00572625-07, A831133, SR-01000721948, Q3077501, SR-01000721948-2, (10R,13S)-4,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione, (8R,9S,10R,13S,14S)-10,13-dimethyl-4-oxidanyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione, (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-quinone. | |
Formestane (4-Hydroxyandrost-4-ene-3,17-dione, 4-OHA, CGP-32349, Lentaron) Quick inquiry Where to buy Suppliers range | An antitumor drug. An aromatase inhibitor. Group: Biochemicals. Alternative Names: 4-Hydroxyandrost-4-ene-3,17-dione, 4-OHA, CGP-32349, Lentaron. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
FR 901537 Quick inquiry Where to buy Suppliers range | FR-901537, a naphthothiazin compound, has been found to be an aromatase inhibitor that could be used as a cytostatic antibiotic and was once studied in breast cancer. Synonyms: FR-901537; FR901537; (R)-N-(3-((2-((2,3-Dihydro-6-hydroxy-2-oxo-1H-naphtho(2,1-b)(1,4)thiazin-5-yl)thio)ethyl)amino)-3-oxopropyl)-2,4-dihydroxy-3,3-dimethylbutanamide. Grades: 98%. CAS No. 161162-21-6. Molecular formula: C23H29N3O6S2. Mole weight: 507.62. | |
Ginsenoside Rg5 Quick inquiry Where to buy Suppliers range | Ginsenoside Rg5 is an aromatase inhibitor from Panax ginseng leaves. Also, it ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of inflammation, oxidative stress, and apoptosis. Group: Biochemicals. Alternative Names: (3 β,12 β,20E)-12-hydroxydammara-20(22),24-dien-3-yl 2-O- β-D-glucopyranosyl- β-D-glucopyranoside. Grades: Highly Purified. CAS No. 186763-78-0. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 767. US Biological Life Sciences. | Worldwide |
Letrozole Quick inquiry Where to buy Suppliers range | A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic. An orally bioavailable non-steroidal triazole compound that acts as a potent and selective inhibitor of aromatase (IC50=140, 350 and 450pM in Dex-treated fibroblasts, MCF-7Ca, and JEG-3 cells, respectively). Competitively, but reversibly binds to the heme iron of aromatase. Does not affect the synthesis of adrenal mineralocorticoid or glucocorticoids. Reported to be highly effective as an anti-estrogenic and anti-proliferative agent in estrogen-rich tumors. Also delays the fusing of the growth plates in adolescents and enhances the effectiveness of growth hormone. Shown to synergistically induce apoptosis and cause tumor regression when combined with IGF-1R inhibitors. Group: Biochemicals. Alternative Names: 4, 4- (1H-1, 2, 4-Triazol-1-ylmethylene) bisbenzonitrile; 4-[1- (4-Cyanophenyl) -1- (1, 2, 4-triazol-1-yl) methyl]benzonitrile; CGS 20267; Femara; Lerozole; Letrazole; Aromatase Inhibitor II. Grades: Highly Purified. CAS No. 112809-51-5. Pack Sizes: 1g, 5g. Molecular Formula: C17H11N5, Molecular Weight: 285.3. US Biological Life Sciences. | Worldwide |
Letrozole-d4 Quick inquiry Where to buy Suppliers range | A deuterated version of Letrozole, a nonsteroidal aromatase inhibitor structurally related to Fadrozole.The current lot is 84% d4, 16% d3, no detectable d2, d1 or d0. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Liarozole Quick inquiry Where to buy Suppliers range | This active molecular has a potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits P450-dependent ATRA-4-hydroxylase to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. Meanwhile, liarozole also inhibits aromatase that catalyzes estrogen biosynthesis in rating-limited step. In Aug 2005, clinical development was ongoing for Ichthyosis in Europe.In Jan 2006, Phase-II/III clinical trials in Ichthyosis was ongoing in Europe and in Canada. Uses: Treatment for ichthyosis. Synonyms: 6-[(3-chlorophenyl)-imidazol-1-ylmethyl]-1H-benzimidazole, R 75251; R-75251; R75251. Grades: 98%. CAS No. 115575-11-6. Molecular formula: C17H13ClN4. Mole weight: 308.771. | |
Liarozole hydrochloride Quick inquiry Where to buy Suppliers range | Liarozole is a benzimidazole derivative with potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits cytochrome P450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, resulting in an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. This agent also inhibits aromatase, the enzyme that catalyzes the final, rate-limiting step in estrogen biosynthesis. Synonyms: Liarozole HCl; R75251 (hydrochloride); 5-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole hydrochloride. CAS No. 145858-50-0. Molecular formula: C17H14Cl2N4. Mole weight: 345.23. | |
LY-113174 Quick inquiry Where to buy Suppliers range | LY-113174 is a novel class of nonsteroidal aromatase inhibitor. It may prove useful in the treatment of estrogen-dependent diseases. Uses: Ly-113174 may prove useful in the treatment of estrogen-dependent diseases. Synonyms: 5H-Indeno[1,2-d]pyrimidine,8-chloro-5-(4-chlorophenyl)-;8-Chloro-5-(4-chlorophenyl)-5H-indeno[1,2-d]pyrimidine; LY 113174; LY113174; LY-113174. Grades: >98%. CAS No. 112959-07-6. Molecular formula: C17H10Cl2N2. Mole weight: 313.18. | |
LY 43578 Quick inquiry Where to buy Suppliers range | LY 43578 is an aromatase inhibitor. Synonyms: bis(4-chlorophenyl)-pyrimidin-5-ylmethanol; LY 43578; LY 43578; LY 43578. Grades: >98%. CAS No. 26766-35-8. Molecular formula: C17H12Cl2N2O. Mole weight: 331.2. | |
LY 56110 Quick inquiry Where to buy Suppliers range | LY 56110, a Pyrimidine derivative, is a novel class of nonsteroidal aromatase inhibitor. LY 56110 inhibited ethinamate-induced sleeping time in rats in vivo. Synonyms: 5-[bis(4-chlorophenyl)methyl]pyrimidine; LY 56110; LY-56110; LY56110. Grades: >98%. CAS No. 26766-37-0. Molecular formula: C17H12Cl2N2. Mole weight: 315.2. | |
Methyl 3,17-Dioxo-4-androsten-19-oate Quick inquiry Where to buy Suppliers range | A methoxy hydroperoxide androstenedione derivative; analog of a potential aromatase intermediate. Group: Biochemicals. Alternative Names: 3,17-Dioxo-androst-4-en-19-oic Acid Methyl Ester. Grades: Highly Purified. CAS No. 22256-03-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Oleuropein Quick inquiry Where to buy Suppliers range | Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase. Group: Biobased Products. Alternative Names: (2S)-3-[(E)-Ethylidene]-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4α-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester. Grades: 99.05%. CAS No. 32619-42-4. Product ID: BBC32619424. Molecular formula: C25H32O13. Mole weight: 540.51. IUPAC Name: Methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate. Appearance: White powder. Density: 1.50±0.1 g/ml. SMILES: C/C=C/1\[C@@H] (C (=CO[C@H]1O[C@H]2[C@@H] ([C@H] ([C@@H] ([C@H] (O2)CO)O)O)O)C (=O)OC)CC (=O)OCCC3=CC (=C (C=C3)O)O. | |
Org30958 Quick inquiry Where to buy Suppliers range | ORG 30958 is a potent aromatase inhibitor in vivo. ORG 30958 proved to be devoid of antiestrogenic activity which indicates that the absence of cornification of vaginal epithelium in DHEAS-treated Hypex rats is induced by the inhibition of the biosynthesis of estrogens and not by an anti-estrogenic activity. Synonyms: (8S,9S,10S,13S,14S)-10-[(ethyldisulfanyl)methyl]-13-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione; 19-(ethyldithio)androst-4-ene-3,17-dione; ORG 30958; ORG-30958. CAS No. 99957-90-1. Molecular formula: C21H30O2S2. Mole weight: 378.59. | |
Palbociclib Impurity 12 Quick inquiry Where to buy Suppliers range | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: tert-butyl 4-(6-((2-chloro-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)amino)pyridin-3-yl)piperazine-1-carboxylate. Grades: > 95%. Molecular formula: C27H34ClN7O3. Mole weight: 540.07. | |
Palbociclib Impurity 13 Quick inquiry Where to buy Suppliers range | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 2-acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. Grades: > 95%. Molecular formula: C24H29N7O2. Mole weight: 447.54. | |
Palbociclib Impurity 7 Quick inquiry Where to buy Suppliers range | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[[6-[(1E)?-2-butoxyethenyl]?-8-cyclopentyl-7,?8-dihydro-5-methyl-7-oxopyrido[2,?3-d]?pyrimidin-2-yl]?amino]?-3-pyridinyl]?-, 1,?1-dimethylethyl ester. Grades: > 95%. CAS No. 827022-35-5. Molecular formula: C33H45N7O4. Mole weight: 603.77. | |
R-(+)-Aminoglutethimide Tartrate Salt (R-(+)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione Tartrate Salt) Quick inquiry Where to buy Suppliers range | An aromatase inhibitor. Also blocks adrenal steroidogenesis. Group: Biochemicals. Alternative Names: R-(+)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione Tartrate Salt. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone Quick inquiry Where to buy Suppliers range | An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase. Group: Biochemicals. Alternative Names: (4S)-4-[(4-aminophenyl)methyl]-2-oxazolidinone; 4S)-4-(4-Aminobenzyl)-1,3-oxazolidin-2-one. Grades: Highly Purified. CAS No. 152305-23-2. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
(S)-4-(4-Hydrazinylbenzyl)-2-oxazolidinone Quick inquiry Where to buy Suppliers range | An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase. Group: Biochemicals. Alternative Names: (4S) -4-[ (4-hydrazinylphenyl) methyl]-2-Oxazolidinone. Grades: Highly Purified. CAS No. 187975-62-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
S-(-)-Aminoglutethimide Tartrate Salt (S-(-)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione Tartrate Salt) Quick inquiry Where to buy Suppliers range | An aromatase inhibitor. Also blocks adrenal steroidogenesis. Group: Biochemicals. Alternative Names: S-(-)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione Tartrate Salt. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |