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| Product | Description | |
|---|---|---|
| Avermectin A1a | Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10. |  |
| 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?demethoxy-?25-?de (1-?methylpropyl) ?-?5-?oxo-avermectin A1a | 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?demethoxy-?25-?de (1-?methylpropyl) ?-?5-?oxo-avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 404578-37-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C43H60O11, Molecular Weight: 752.93. US Biological Life Sciences. |  Worldwide |
| 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?O-?demethyl-?25-?de (1-?methylpropyl) ?-Avermectin A1a | 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?O-?demethyl-?25-?de (1-?methylpropyl) ?-Avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 165108-44-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C43H62O11, Molecular Weight: 754.95. US Biological Life Sciences. | Worldwide |
| 25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-oxo-avermectin A1a | 25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-oxo-avermectin A1a is an intermediate in synthesizing 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin (D440100), which s an impurity of Selamectin (S247990), a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 220119-16-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C50H74O14. US Biological Life Sciences. | Worldwide |
| 5-O-demethyl-28-hydroxy-Avermectin A1a | 5-O-demethyl-28-hydroxy-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-. Appearance: White to off-white solid. CAS No. 96722-46-2. Molecular formula: C48H72O15. Mole weight: 889.09. Purity: 0.95. Product ID: ACM96722462. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 5-O-Demethyl-28-oxo-Avermectin A1a | 5-O-Demethyl-28-oxo-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq]. Appearance: Pale yellow to light yellow solid. CAS No. 102190-68-1. Molecular formula: C48H70O15. Mole weight: 887.07. Purity: 0.98. IUPACName: (1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'Z,20'R,21'R,24'S)-2-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2',18'-dione. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\C(=O)O[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM102190681. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a | 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,4-Dihydro Ivermectin (Mixture of Diastereomers). Appearance: White to off-white solid. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.11. Purity: 0.95. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16-triene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](CC([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM74567014. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-28-oxo-Avermectin A1a | 5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-28-oxo-Avermectin A1a is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 102190-51-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C60H100O15Si2. US Biological Life Sciences. | Worldwide |
| 5-O-Demethyl-4'',5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-22,23-dihydro-28-oxo-Avermectin A1a | 5-O-Demethyl-4'',5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-22,23-dihydro-28-oxo-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], Avermectin A1a Deriv. Appearance: White solid. CAS No. 102190-51-2. Molecular formula: C60H100O15Si2. Mole weight: 1117.6. IUPACName: (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21-[tert-butyl(dimethyl)silyl]oxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-[tert-butyl(dimethyl)silyl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-24-hydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2,18-dione. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)CC=C([C@H]([C@H](C=CC=C4C(=O)O[C@H]5[C@@]4([C@@H](C=C([C@H]5O[Si](C)(C)C(C)(C)C)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O[Si](C)(C)C(C)(C)C)OC)OC)C)C. Product ID: ACM102190512. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-Avermectin A1a | 5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-Avermectin A1a is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 82590-57-6. Pack Sizes: 5mg, 25mg. Molecular Formula: C60H102O14Si2. US Biological Life Sciences. | Worldwide |
| 5-O-Demethyl-4'',5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-22,23-dihydro-Avermectin A1a | 5-O-Demethyl-4'',5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-22,23-dihydro-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], Avermectin A1a deriv. Appearance: White to pale yellow solid. CAS No. 82590-57-6. Molecular formula: C60H102O14Si2. Mole weight: 1103.61. IUPACName: (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21-[tert-butyl(dimethyl)silyl]oxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-[tert-butyl(dimethyl)silyl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-24-hydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)CC=C([C@H]([C@H](C=CC=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O[Si](C)(C)C(C)(C)C)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O[Si](C)(C)C(C)(C)C)OC)OC)C)C. Product ID: ACM82590576. Alfa Chemistry ISO 9001:2015 Certified. | |
| Avermectin B1a (5-O-Demethylavermectin A1a, Antibiotic C 076B1a) | Avermectin B1a is the major component (>80%) of the commerically available anthelmintic Abamectin (R) used to control parasitic nematodes in livestock. Avermectin B1a contains a secbutyl residue in the 24-position. In vitro and in vivo studies have shown this analogue is the more potent analogue in the commerical product. Group: Biochemicals. Alternative Names: 5-O-Demethylavermectin A1a, Antibiotic C 076B1a. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Doramectin (25-Cyclohexyl-5-O-demethyl-25-de (1-methylpropyl) avermectin A1A,. 25-Cylohexyl-avermectin B1, UK-67994, Dectomax) | Doramectin is a biosynthetic avermectin derived from a mutant of the original Streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin / avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. Group: Biochemicals. Alternative Names: 25-Cyclohexyl-5-O-demethyl-25-de (1-methylpropyl) avermectin A1A; 25-Cylohexyl-avermectin B1; UK-67994; Dectomax. Grades: Highly Purified. CAS No. 117704-25-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 28-Oxo Ivermectin B1a (Impurity) | 28-Oxo Ivermectin B1a (Impurity). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a. Appearance: White to off-white solid. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.08. Purity: 0.95. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2,18-dione. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\C(=O)O[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM102190556. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3"-O-Demethyl ivermectin | 3"-O-Demethyl ivermectin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.3''-O-Desmethyldihydroavermectin B1a. Appearance: White solid. CAS No. 92137-95-6. Molecular formula: C47H72O14. Mole weight: 861.08. Purity: 0.95. IUPACName: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-12-[(2R,4S,5S,6S)-5-[(2S,4S,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-21,24-dihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)O)OC)/C)C. Product ID: ACM92137956. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4a-Hydroxy Ivermectin | 4a-Hydroxy Ivermectin. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv. CAS No. 86629-74-5. Pack Sizes: 1MG. Molecular formula: C48H74O15. Mole weight: 891.09. Catalog: APS86629745. SMILES: CC[C@@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(/C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@]67O)CO)O2. Format: Neat. Shipping: Room Temperature. |  |
| 5-Dehydroxyl-5-oxodoramectin | 5-Dehydroxyl-5-oxodoramectin. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.,25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-5-oxo-avermectin A1a (9CI). CAS No. 157483-78-8. Molecular formula: C50H72O14. Mole weight: 897.10. Catalog: APS157483788. SMILES: CO[C@H]1C[C@H](O[C@H]2[C@H](C)O[C@H](C[C@@H]2OC)O[C@H]3[C@@H](C)\C=C\C=C\4/CO[C@@H]5C(=O)C(=C[C@@H](C(=O)O[C@H]6C[C@@H](C\C=C\3/C)O[C@@]7(C6)O[C@H](C8CCCCC8)[C@@H](C)C=C7)[C@]45O)C)O[C@@H](C)[C@@H]1O. Format: Neat. Shipping: Room Temperature. | |
| Avermectin A2a | Avermectin A2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a had the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22,23-dihydroabamectin B1a (above 80%) and 22,23 dioxabamectin B1b(below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Avermectin A1a; SCHEMBL1681224. CAS No. 50914-15-3. Molecular formula: C49H76O15. Mole weight: 905.12. | |
| Avermectin B1a monosaccharide | It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Synonyms: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grades: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91. | |
| delta2-Avermectin B1a | Δ2-Avermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 0.23 and 0.038 ppm, respectively). Synonyms: Avermectin A1a, 2,3-didehydro-5-O-demethyl-3,4-dihydro-, (4S)-; Δ2-4(R)-avermectin B1a; Δ2-Avermectin B1a. Grades: >95% by HPLC. CAS No. 110415-68-4. Molecular formula: C48H72O14. Mole weight: 873.07. | |
| delta2-Doramectin | An irreversible base degradation product of doramectin found in animals treated with doramectin and in the environment. It is formed by rearrangement of the naturally occurring 3-group in doramectin to the 2-position. It is an anthelmintic in animal health. Synonyms: (4S)-25-cyclohexyl-2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-3,4-dihydro-avermectin A1a; Doramectin, delta2-; Δ2-Doramectin. Grades: >95% by HPLC. CAS No. 1987882-63-2. Molecular formula: C50H74O14. Mole weight: 899.11. | |
| Doramectin | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespharma & vet compounds & metabolitesstable isotope labelled compoundsstandards for environmental regulatory methodspharma & vet compounds & metabolitesapi standardspharmaceutical toxicology. Alternative Names: 25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a, 25-Cyclohexylavermectin B1, 25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin a1a, L 701023, Dectomax, Doramectin, Doramectin A1a, Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv., UK 67994. | |
| Doramectin | Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 25-CYCLOHEXYL-5-O-DEMETHYL-25-DE(1-METHYLPROPYL)AVERMECTIN;DORAMECTIN;Doramectin VETRANAL;Doromectin;_x00B_25-Cclohexyl-avermectin B1;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1A;Dectoma;UK-67994. Product Category: Inhibitors. Appearance: Solid. CAS No. 117704-25-3. Molecular formula: C50H74O14. Mole weight: 899.11. Purity: 0.9896. Canonical SMILES: CO[C@@H]1[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O[C@@]([H])(O[C@H](/C(C)=C/C[C@]3([H])C[C@]([H])(OC4=O)C[C@]5(C=C[C@H](C)[C@@H](C6CCCCC6)O5)O3)[C@@H](C)/C=C/C=C7CO[C@@]8([H])[C@]\7(O)[C@@]4([H])C=C(C)[C@H]8O)C1. Product ID: ACM117704253. Alfa Chemistry ISO 9001:2015 Certified. | |
| Doramectin monosaccharide | It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of doramectin. It is a potent inhibitor of nematode larval development and an anthelmintic in animal health. Synonyms: 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a. Grades: >95% by HPLC. CAS No. 165108-44-1. Molecular formula: C43H62O11. Mole weight: 754.95. | |
| Emamectin B1a | It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4''-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: L 656748; (4''R)-5-O-Demethyl-4''-deoxy-4''-(methylamino)avermectin A1a; 4''-Deoxy-4''-epi-(methylamino)avermectin B1a. Grades: >99% by HPLC. CAS No. 121124-29-6. Molecular formula: C49H75NO13. Mole weight: 886.12. | |
| Emamectin B1b | It is a semi-synthetic 4-epimethylamino analogue of avermectin B1b. It is prepared by oxidation of the 4-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-4''-(methylamino)-25-(1-methylethyl)-, (4''R)-. Grades: >99% by HPLC. CAS No. 121424-52-0. Molecular formula: C48H73NO13. Mole weight: 872.09. | |
| epi-Avermectin B1a | It is a base-catalysed intermediate in the decomposition of avermectin B1a. It has only very weak activity as a nematocide showing 100-fold less of biological activity compared with the parent avermectin. It is an environmental degradation product. Synonyms: Avermectin B1a, epi-; 2-epi-Abamectin; (2S)-5-O-demethyl-avermectin A1a. Grades: >95% by HPLC. CAS No. 106434-14-4. Molecular formula: C48H72O14. Mole weight: 873.08. | |
| Epi-doramectin | It is a base-catalysed intermediate in the decomposition of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Synonyms: (2S)-25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a; Doramectin, epi-. Grades: >95% by HPLC. CAS No. 1987882-62-1. Molecular formula: C50H74O14. Mole weight: 899.11. | |
| epi-Ivermectin B1a | Epi-Ivermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 4.0 and 0.038 ppm, respectively). Synonyms: 5-O-demethyl-22,23-dihydro-avermectin A1a; 2-dehydro-4-dihydro Avermectin B1a; epi-dihydro Avermectin B1a; 22,23-dihydro Avermectin B1a; 2-epi-Ivermectin B1a. Grades: >95% by HPLC. Molecular formula: C48H74O14. Mole weight: 875.09. | |
| Eprinomectin B1a | It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination. Members of the Avermectin/Milbemycin class exert their insecticidal/anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-4''-deoxyavermectin A1a; Avermectin A1a, 4'-(acetylamino)-5-O-demethyl-4'-deoxy-, (4'R)-; Eprinomectin component B1a. Grades: >99% by HPLC. CAS No. 133305-88-1. Molecular formula: C50H75NO14. Mole weight: 914.13. | |
| Eprinomectin B1b | It is a semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination followed by acetylation. It is the minor component (<10%) of the commercial product for endo- and exo-parasite control, eprinomectin. It is a potent insecticide and acaricide. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a; Eprinomectin component B1b. Grades:>99% by HPLC. CAS No. 133305-89-2. Molecular formula: C49H73NO14. Mole weight: 900.10. | |
| Ivermectin B1a | It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Dihydroavermectin B1a; Ivermectin; 22,23-Dihydroavermectin B1a; 5-O-Demethyl-22,23-dihydro-avermectin A1a; Ivermectin Impurity I. Grades: >95% by HPLC. CAS No. 70161-11-4. Molecular formula: C48H74O14. Mole weight: 875.12. | |
| Ivermectin B1a | Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310). Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09. Purity: 0.85. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ivermectin B1a | Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences. | Worldwide |
| Ivermectin B1a-D2 | Ivermectin B1a-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a-D2. Appearance: Pale Beige to Brown Solid. CAS No. 71827-03-7 (Unlabelled). Molecular formula: C48H72D2O14. Mole weight: 877.11. Purity: 0.94. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-2. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ivermectin B1 monosaccharide | Ivermectin B1 monosaccharide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a. Appearance: White to off-white solid. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. Purity: 0.98. IUPACName: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)/C)C. Product ID: ACM71837279. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ivermectin B1a monosaccharide. | |
| Ivermectin Impurity D | an impurity of Ivermectin. Synonyms: 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10. | |
| Ivermectin Impurity H | an impurity of Ivermectin. Synonyms: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. | |
| Ivermectin Impurity K | an impurity of Ivermectin. Synonyms: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13. | |
| Ivermectin monosaccharide | A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. Grades: >99% by HPLC. CAS No. 123997-64-8. Molecular formula: C41H62O11. Mole weight: 730.92. | |
| Selamectin | analytical standard. Group: Application areaspesticides & metabolitespharma & vet compounds & metabolitesstable isotope labelled compoundspesticides & metabolitespharma & vet compounds & metabolitesstable isotope labelled compoundseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Revolution (antibiotic), Stronghold, Selamectin,(5Z)-25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-?-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin A1a, Revolution. | |
| Selamectin | Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Selamectin;hypnocarpic acid;AverMectin A1a,25-cyclohexyl-4-O-de(2,6-dideoxy-3-O-Methyl-a-L-arabino-hexopyranosyl)-5-deMethoxy-25-de(1-Methylpropyl)-22,23-dihydro-5-(hydroxyiMino)-,(5Z)-;(5Z)-25-Cyclohexyl-4-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a;Revolution (antibiotic);Stronghold. Product Category: Inhibitors. Appearance: Solid. CAS No. 220119-17-5. Molecular formula: C43H63NO11. Mole weight: 769.967. Purity: 0.9905. Canonical SMILES: O[C@@]12[C@@]3([H])/C(C(C)=C[C@@]1([H])C(O[C@]4([H])C[C@]5(O[C@@](C/C=C(C)/[C@@H](O[C@@]6([H])C[C@@H]([C@@H](O)[C@H](C)O6)OC)[C@@H](C)/C=C/C=C2\CO3)([H])C4)O[C@H](C7CCCCC7)[C@@H](C)CC5)=O)=N\O. Product ID: ACM220119175. Alfa Chemistry ISO 9001:2015 Certified. | |
| Selamectin | Selamectin. Group: Biochemicals. Alternative Names: Revolution (antibiotic); Stronghold; (5Z) -25-Cyclohexyl-4'-O-de (2, 6-dideoxy-3-O-methyl-α -L-arabino-hexopyranosyl) -5-demethoxy-25-de (1-methylpropyl) -22, 23-dihydro-5- (hydroxyimino) avermectin A1a. Grades: Highly Purified. CAS No. 220119-17-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Selamectin Impurity A | An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: (2aE, 2'R, 4E, 4'S, 5'S, 6S, 6'R, 7S, 8E, 11R, 15S, 17aR, 20Z, 20aR, 20bS)-6'-cyclohexyl-7-[(2, 6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-4', 20b-dihydroxy-20-(hydroxyimino)-5', 6, 8, 19-tetramethyl-3', 4', 5', 6, 6', 7, 10, 11, 14, 15, 17a, 20, 20a, 20b-tetradecahydrospiro[2H, 17H-11, 15-methanofuro[4, 3, 2-pq][2, 6]benzodioxacyclooctadecine-13, 2'-pyran]-17-one ((5Z,21R,23S,25R)-25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-23-hydroxy-5-(hydroxyimino)avermectin A1a). Grades: > 95%. Molecular formula: C43H63NO12. Mole weight: 785.96. | |
| Selamectin Impurity B | An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: 25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-5-(hydroxyimino)-avermectin A1a; 22,23-Didehydro Selamectin. Grades: > 95%. CAS No. 165108-09-8. Molecular formula: C43H61NO11. Mole weight: 767.97. | |
| Selamectin Impurity D | An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: 25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a; 22,23-Dihydro-5-hydroxyimino Doramectin; 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin. Grades: > 95%. CAS No. 301849-46-7. Molecular formula: C50H75NO14. Mole weight: 914.15. | |
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