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| Product | Description | |
|---|---|---|
| Axitinib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Axitinib | Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Uses: Protein kinase inhibitors. Synonyms: AG 013736; N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide; Inlyta. Grade: ≥98%. CAS No. 319460-85-0. Molecular formula: C22H18N4OS. Mole weight: 386.5. |  |
| Axitinib | Axitinib. Group: Biochemicals. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736. Grades: Highly Purified. CAS No. 319460-85-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H18N4OS. US Biological Life Sciences. |  Worldwide |
| Axitinib | Axitinib is a multi-targeted tyrosine kinase inhibitor with IC 50 s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1 , VEGFR2 , VEGFR3 and PDGFRβ , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-013736. CAS No. 319460-85-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10065. |  |
| Axitinib-[13C,d3] | Axitinib-[13C,d3] is a labelled Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: [13C,2H3]-N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; (E)-N-(methyl-13C-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. Grade: > 98%. CAS No. 1261432-00-1. Molecular formula: C21[13C]H15D3N4OS. Mole weight: 390.48. | |
| Axitinib-d3 | Labeled analogue of Axitinib, a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. Group: Biochemicals. Alternative Names: N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Axitinib-[d3] | Axitinib-[d3] is the labelled analogue of Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: Axitinib D3; N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3; Axitinib-d3 (N-methyl-d3). Grade: 95% by HPLC; 98% atom D. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49. | |
| Axitinib-D3 (Axitinib Impurity 36) | Axitinib-D3 (Axitinib Impurity 36). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49. Catalog: APB1126623899. | |
| Axitinib Impurity 1 | Axitinib Impurity 1 is an impurity of Axitinib, a drug primarily used in the treatment of advanced renal cell carcinoma and metastatic thyroid cancer. Synonyms: Axitinib Impurity c. Grade: > 95%. CAS No. 885126-40-9. Molecular formula: C22H18N4OS. Mole weight: 386.48. | |
| Axitinib Impurity 2 | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: 2,2'-((6,6'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide). Grade: > 95%. CAS No. 1428728-83-9. Molecular formula: C44H36N8O2S2. Mole weight: 772.96. | |
| Axitinib Impurity 6 | Axitinib Impurity 6 is an impurity arising from the depths of Axitinib - an oral tyrosine kinase inhibitor profoundly employed in the therapy against advanced renal carcinoma. Synonyms: Axitinib Impurity d. Grade: > 95%. CAS No. 1443118-72-6. Molecular formula: C29H25N5OS. Mole weight: 491.62. | |
| Axitinib Impurity 8 | Axitinib Impurity 8 is an impurity of axitinib fortifying the therapy against the perilous adversity known as advanced renal carcinoma. Synonyms: 2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide; BenzaMide, 2-(1H-indazol-6-ylthio)-N-Methyl-; Axitinib Impurity e. Grade: > 95%. CAS No. 944835-85-2. Molecular formula: C15H13N3OS. Mole weight: 283.35. | |
| Axitinib Impurity C | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: 2-((1H-Indazol-6-yl)sulfinyl)-N-methylbenzamide; Axitinib EP Impurity C; Axitinib Impurity 56. Grade: ≥95%. CAS No. 1959572-97-4. Molecular formula: C15H13N3O2S. Mole weight: 299.35. | |
| Axitinib Impurity D | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: 2-[(1-Acetyl-1H-indazol-6-yl)sulfinyl]-N-methylbenzamide; Axitinib EP Impurity D. Grade: ≥95%. CAS No. 1959572-98-5. Molecular formula: C17H15N3O3S. Mole weight: 341.38. | |
| Axitinib N-oxide | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: (E)-N-Methyl-2-[[3-[2-(1-oxido-2-pyridinyl)ethenyl]-2H-indazol-6-yl]thio]benzamide. Grade: ≥95%. Molecular formula: C22H18N4O2S. Mole weight: 402.47. | |
| Axitinib sulfone | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: Sulfonyl axitinib; (E)-N-methyl-2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylsulfonyl)benzamide; N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide. Grade: ≥95%. CAS No. 1348536-59-3. Molecular formula: C22H18N4O3S. Mole weight: 418.47. | |
| Axitinib sulfoxide | A major metabolite of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide; Axitinib Impurity A. Grade: > 95%. CAS No. 1347304-18-0. Molecular formula: C22H18N4O2S. Mole weight: 402.48. | |
| AG013736 (AxitinibAxitinib) | Axitinib (also known as AG013736) is a small molecule tyrosine kinase inhibitor under development by Pfizer. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft models [1] and has been successful in trials with renal cell carcinoma (RCC) [2] and several other tumor types [3]. Group: Biochemicals. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736. Grades: Purified. CAS No. 319460-85-0. Pack Sizes: 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Dihydro-Axitinib | Dihydro-Axitinib is an impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Grade: > 95%. CAS No. 1443118-73-7. Molecular formula: C22H20N4OS. Mole weight: 388.49. | |
| 2-((1-Acetyl-3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: Benzamide, 2-[(1-acetyl-3-iodo-1H-indazol-6-yl)thio]-N-methyl-; Axitinib impurity YXA. Grade: ≥95%. CAS No. 1639138-00-3. Molecular formula: C17H14IN3O2S. Mole weight: 451.28. | |
| 2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: Benzamide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-methyl-. Grade: > 95%. CAS No. 885126-34-1. Molecular formula: C15H12IN3OS. Mole weight: 409.25. | |
| 2-Mercapto-N-methyl-benzamide | 2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 20054-45-9. Pack Sizes: 1g, 5g. Molecular Formula: C8H9NOS, Molecular Weight: 167.23. US Biological Life Sciences. | Worldwide |
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