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| Product | Description | |
|---|---|---|
| 10-deoxymethynolide desosaminyltransferase | DesVII is the glycosyltransferase responsible for the attachment of dTDP-D-desosamine to 10-deoxymethynolide or narbonolide during the biosynthesis of methymycin, neomethymycin, narbomycin, and pikromycin in the bacterium Streptomyces venezuelae. Activity requires an additional protein partner, DesVIII. Group: Enzymes. Synonyms: glycosyltransferase DesVII; DesVII. Enzyme Commission Number: EC 2.4.1.277. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2509; 10-deoxymethynolide desosaminyltransferase; EC 2.4.1.277; glycosyltransferase DesVII; DesVII. Cat No: EXWM-2509. |  |
| 10-deoxymethynolide synthase | The product, 10-deoxymethynolide, contains a 12-membered ring and is an intermediate in the biosynthesis of methymycin in the bacterium Streptomyces venezuelae. The enzyme also produces narbonolide (see EC 2.3.1.240, narbonolide synthase). The enzyme has 29 active sites arranged in four polypeptides (pikAI - pikAIV) with a loading domain, six extension modules and a terminal thioesterase domain. Each extension module contains a ketosynthase (KS), keto reductase (KR), an acyltransferase (AT) and an acyl-carrier protein (ACP). Not all active sites are used in the biosynthesis. Group: Enzymes. Synonyms: pikromycin PKS. Enzyme Commission Number: EC 2.3.1.239. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2187; 10-deoxymethynolide synthase; EC 2.3.1.239; pikromycin PKS. Cat No: EXWM-2187. | |
| 1-deoxy-11β-hydroxypentalenate dehydrogenase | Isolated from the bacterium Streptomyces avermitilis and present in many other Streptomyces species. Part of the pathway for pentalenolactone biosynthesis. Group: Enzymes. Synonyms: 1-deoxy-11β-hydroxypentalenic acid dehydrogenase; ptlF (gene name); penF (gene name). Enzyme Commission Number: EC 1.1.1.340. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0255; 1-deoxy-11β-hydroxypentalenate dehydrogenase; EC 1.1.1.340; 1-deoxy-11β-hydroxypentalenic acid dehydrogenase; ptlF (gene name); penF (gene name). Cat No: EXWM-0255. | |
| 1-deoxypentalenic acid 11β-hydroxylase | The enzyme requires Fe(II) and ascorbate. Isolated from the bacterium Streptomyces avermitilis. Part of the pathway for pentalenolactone biosynthesis. Group: Enzymes. Synonyms: ptlH (gene name); sav2991 (gene name); pntH (gene name). Enzyme Commission Number: EC 1.14.11.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0653; 1-deoxypentalenic acid 11β-hydroxylase; EC 1.14.11.35; ptlH (gene name); sav2991 (gene name); pntH (gene name). Cat No: EXWM-0653. | |
| (1R,2S)-m-nitro-erythro-Chloramphenicol | (1R,2S)-m-nitro-erythro-Chloramphenicol is an analog of Chloramphenicol (C325030); a broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against gram-positive and gram-negative bacteria. Also antibacterial and antirickettsial. Group: Biochemicals. Grades: Highly Purified. CAS No. 1327173-91-0. Pack Sizes: 500ug, 5mg. Molecular Formula: C11H12Cl2N2O5, Molecular Weight: 323.13. US Biological Life Sciences. |  Worldwide |
| (1S,2R)-m-nitro-erythro-Chloramphenicol | (1S,2R)-m-nitro-erythro-Chloramphenicol is an analog of Chloramphenicol (C325030); a broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against gram-positive and gram-negative bacteria. Also antibacterial and antirickettsial. Group: Biochemicals. Grades: Highly Purified. CAS No. 1327173-88-5. Pack Sizes: 500ug, 5mg. Molecular Formula: C11H12Cl2N2O5, Molecular Weight: 323.13. US Biological Life Sciences. | Worldwide |
| 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | The enzyme from the bacterium Streptomyces carzinostaticus is involved in the biosynthesis of 2-hydroxy-7-methoxy-5-methyl-1-naphthoate. This compound is part of the enediyne chromophore of the antitumor antibiotic neocarzinostatin. In vivo the enzyme catalyses the regiospecific methylation at the 7-hydroxy group of its native substrate 2,7-dihydroxy-5-methyl-1-naphthoate. In vitro it also recognizes other dihydroxynaphthoic acids and catalyses their regiospecific O-methylation. Group: Enzymes. Synonyms: NcsB1; neocarzinostatin O-methyltransferase. Enzyme Commission Number: EC 2.1.1.303. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1911; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase; EC 2.1.1.303; NcsB1; neocarzinostatin O-methyltransferase. Cat No: EXWM-1911. | |
| 2'''-acetyl-6'''-hydroxyneomycin C deacetylase | Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 3.5.1.112, 2'-N-acetylparomamine deacetylase. Group: Enzymes. Synonyms: neoL (gene name). Enzyme Commission Number: EC 3.5.1.113. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4393; 2'''-acetyl-6'''-hydroxyneomycin C deacetylase; EC 3.5.1.113; neoL (gene name). Cat No: EXWM-4393. | |
| 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase | Part of the pathway for the biosynthesis of grixazone, a mixture of yellow pigments produced by the bacterium Streptomyces griseus. Group: Enzymes. Synonyms: griI (gene name). Enzyme Commission Number: EC 4.1.2.56. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4893; 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase; EC 4.1.2.56; griI (gene name). Cat No: EXWM-4893. | |
| 2'-deamino-2'-hydroxyneamine 1-α-D-kanosaminyltransferase | Involved in the biosynthetic pathway of kanamycins. The enzyme characterized from the bacterium Streptomyces kanamyceticus can also accept UDP-α-D-glucose with lower efficiency. Group: Enzymes. Synonyms: kanE (gene name); kanM2 (gene name). Enzyme Commission Number: EC 2.4.1.301. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2536; 2'-deamino-2'-hydroxyneamine 1-α-D-kanosaminyltransferase; EC 2.4.1.301; kanE (gene name); kanM2 (gene name). Cat No: EXWM-2536. | |
| 2'-deamino-2'-hydroxyneamine transaminase | The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathway of kanamycin A and kanamycin D. The enzyme, characterized from the bacterium Streptomyces kanamyceticus, can also catalyse EC 2.6.1.93, neamine transaminase. Group: Enzymes. Synonyms: kacL (gene name). Enzyme Commission Number: EC 2.6.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2935; 2'-deamino-2'-hydroxyneamine transaminase; EC 2.6.1.94; kacL (gene name). Cat No: EXWM-2935. | |
| 2'-dehydrokanamycin reductase | Found in the bacterium Streptomyces kanamyceticus where it is involved in the conversion of kanamycin B to kanamycin A. Group: Enzymes. Synonyms: kanK (gene name, ambiguous). Enzyme Commission Number: EC 1.1.1.355. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0271; 2'-dehydrokanamycin reductase; EC 1.1.1.355; kanK (gene name, ambiguous). Cat No: EXWM-0271. | |
| 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase | Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Unlike the enzyme from the bacterium Streptomyces kanamyceticus, which can also accept UDP-D-glucose (cf. EC 2.4.1.284, 2-deoxystreptamine glucosyltransferase), the enzyme from Bacillus circulans can only accept UDP-N-acetyl-α-D-glucosamine. Group: Enzymes. Synonyms: btrM (gene name); neoD (gene name); kanF (gene name). Enzyme Commission Number: EC 2.4.1.283. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2516; 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase; EC 2.4.1.283; btrM (gene name); neoD (gene name); kanF (gene name). Cat No: EXWM-2516. | |
| 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase | A heme-thiolate protein (P-450) enzyme involved in the synthesis of neocarzinostatin in the bacterium Streptomyces carzinostaticus. Group: Enzymes. Synonyms: NcsB3. Enzyme Commission Number: EC 1.14.99.49. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1059; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase; EC 1.14.99.49; NcsB3. Cat No: EXWM-1059. | |
| 2-hydroxy-7-methoxy-5-methyl-1-naphthoate-CoA ligase | The enzyme from the bacterium Streptomyces carzinostaticus is involved in the attachment of the 2-hydroxy-7-methoxy-5-methyl-1-naphthoate moiety of the antibiotic neocarzinostatin. In vitro the enzyme also catalyses the activation of other 1-naphthoic acid analogues, e.g. 2-hydroxy-5-methyl-1-naphthoate or 2,7-dihydroxy-5-methyl-1-naphthoate. Group: Enzymes. Synonyms: NcsB2. Enzyme Commission Number: EC 6.2.1.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5702; 2-hydroxy-7-methoxy-5-methyl-1-naphthoate-CoA ligase; EC 6.2.1.43; NcsB2. Cat No: EXWM-5702. | |
| 2-hydroxyethylphosphonate methyltransferase | Requires cobalamin. The enzyme, isolated from the bacterium Streptomyces wedmorensis, is a member of the 'AdoMet radical' (radical SAM) family. Involved in fosfomycin biosynthesis. Group: Enzymes. Synonyms: Fom3. Enzyme Commission Number: EC 2.1.1.308. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1916; 2-hydroxyethylphosphonate methyltransferase; EC 2.1.1.308; Fom3. Cat No: EXWM-1916. | |
| 2-methyl-1-pyrroline reductase | The enzyme from the bacterium Streptomyces sp. GF3587 is highly specific for its substrate and forms only the (R) isomer. Group: Enzymes. Synonyms: (R)-imine reductase (ambiguous). Enzyme Commission Number: EC 1.5.1.48. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1529; 2-methyl-1-pyrroline reductase; EC 1.5.1.48; (R)-imine reductase (ambiguous). Cat No: EXWM-1529. | |
| 2'-N-acetylparomamine deacetylase | Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. The enzyme from the bacterium Streptomyces fradiae can also accept 2'''-acetyl-6'''-hydroxyneomycin C as substrate, cf. EC 3.5.1.113, 2'''-acetyl-6'''-hydroxyneomycin C deacetylase. Group: Enzymes. Synonyms: btrD (gene name); neoL (gene name); kanN (gene name). Enzyme Commission Number: EC 3.5.1.112. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4392; 2'-N-acetylparomamine deacetylase; EC 3.5.1.112; btrD (gene name); neoL (gene name); kanN (gene name). Cat No: EXWM-4392. | |
| 3-amino-4-hydroxybenzoate synthase | Requires Mn2+ for maximum activity. The reaction is suggested to take place in several steps. Schiff base formation, double bond migration and dephosphorylation followed by ring opening and closing to form a pyrrolidine ring, and finally dehydration to form the product 3-amino-4-hydroxybenzoate. In the bacterium Streptomyces griseus the enzyme is involved in biosynthesis of grixazone, a yellow pigment that contains a phenoxazinone chromophore. Group: Enzymes. Synonyms: 3,4-AHBA synthase; griH (gene name). Enzyme Commission Number: EC 4.1.99.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4934; 3-amino-4-hydroxybenzoate synthase; EC 4.1.99.20; 3,4-AHBA synthase; griH (gene name). Cat No: EXWM-4934. | |
| 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase | The enzyme from the bacterium Streptomyces sahachiroi is involved in the biosynthesis of 3-methoxy-5-methyl-1-naphthoate, a component of of the the antitumor antibiotic azinomycin B. Group: Enzymes. Synonyms: AziB2. Enzyme Commission Number: EC 2.1.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1910; 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase; EC 2.1.1.302; AziB2. Cat No: EXWM-1910. | |
| 3-methyl-L-tyrosine peroxygenase | The heme-containing peroxygenase from the bacterium Streptomyces lavendulae is involved in biosynthesis of saframycin A, a potent antitumor antibiotic that belongs to the tetrahydroisoquinoline family. Group: Enzymes. Synonyms: SfmD; SacD; 3-methyltyrosine peroxidase; 3-methyl-L-tyrosine peroxidase. Enzyme Commission Number: EC 1.11.2.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0516; 3-methyl-L-tyrosine peroxygenase; EC 1.11.2.5; SfmD; SacD; 3-methyltyrosine peroxidase; 3-methyl-L-tyrosine peroxidase. Cat No: EXWM-0516. | |
| (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase | The enzyme from the bacterium Streptomyces globisporus is involved in the biosynthesis of the (S)-3-chloro-5-hydroxy-β-tyrosine moiety prior to incorporation into the chromoprotein antitumor antibiotic C-1027. Group: Enzymes. Synonyms: SgcC. Enzyme Commission Number: EC 1.14.14.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0912; (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase; EC 1.14.14.15; SgcC. Cat No: EXWM-0912. | |
| 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase | The enzyme is involved in the biosynthesis of prenylated phenazines by the bacterium Streptomyces anulatus. It is specific for both dimethylallyl diphosphate and 5,10-dihydrophenazine-1-carboxylate. Group: Enzymes. Synonyms: PpzP; dihydrophenazine-1-carboxylate dimethylallyltransferase; 5,10-dihydrophenazine 1-carboxylate dimethylallyltransferase. Enzyme Commission Number: EC 2.5.1.121. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2737; 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase; EC 2.5.1.121; PpzP; dihydrophenazine-1-carboxylate dimethylallyltransferase; 5,10-dihydrophenazine 1-carboxylate dimethylallyltransferase. Cat No: EXWM-2737. | |
| 5-methyl-1-naphthoate 3-hydroxylase | The enzyme from the bacterium Streptomyces sahachiroi is involved in the biosynthesis of 3-methoxy-5-methyl-1-naphthoate, a component of of the the antitumor antibiotic azinomycin B. Group: Enzymes. Synonyms: AziB1. Enzyme Commission Number: EC 1.14.13.189. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0788; 5-methyl-1-naphthoate 3-hydroxylase; EC 1.14.13.189; AziB1. Cat No: EXWM-0788. | |
| 5-methylnaphthoic acid synthase | A multi-domain polyketide synthase involved in the synthesis of azinomycin B in the bacterium Streptomyces griseofuscus. Group: Enzymes. Synonyms: AziB. Enzyme Commission Number: EC 2.3.1.236. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2184; 5-methylnaphthoic acid synthase; EC 2.3.1.236; AziB. Cat No: EXWM-2184. | |
| 6-linalyl-2-O,3-dimethylflaviolin synthase | The enzyme is involved in biosynthesis of the polyketide-isoprenoid furaquinocin D in the bacterium Streptomyces sp. KO-3988. It catalyses the transfer of a geranyl group to 2-O,3-dimethylflaviolin to yield 6-linalyl-2-O,3-dimethylflaviolin and 7-O-geranyl-2-O,3-dimethylflaviolin (cf. EC 2.5.1.125, 7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase) in a 10:1 ratio. Group: Enzymes. Synonyms: Fur7; 6-(3,7-dimethylocta-1,6-dien-3-yl)-5,7-dihydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase. Enzyme Commission Number: EC 2.5.1.124. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2740; 6-linalyl-2-O,3-dimethylflaviolin synthase; EC 2.5.1.124; Fur7; 6-(3,7-dimethylocta-1,6-dien-3-yl)-5,7-dihydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase. Cat No: EXWM-2740. | |
| 7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase | The enzyme is involved in furaquinocin biosynthesis in the bacterium Streptomyces sp. KO-3988. It catalyses the transfer of a geranyl group to 2-O,3-dimethylflaviolin to yield 7-O-geranyl-2-O,3-dimethylflaviolin and 6-linalyl-2-O,3-dimethylflaviolin (cf. EC 2.5.1.124, 6-linalyl-2-O,3-dimethylflaviolin synthase) in a 1:10 ratio. Group: Enzymes. Synonyms: Fur7. Enzyme Commission Number: EC 2.5.1.125. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2741; 7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase; EC 2.5.1.125; Fur7. Cat No: EXWM-2741. | |
| 8-demethyl-8-(2,3-dimethoxy-α-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase | The enzyme from the bacterium Streptomyces olivaceus is involved in the biosynthesis of the polyketide elloramycin. Group: Enzymes. Synonyms: ElmMIII. Enzyme Commission Number: EC 2.1.1.307. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1915; 8-demethyl-8-(2,3-dimethoxy-α-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase; EC 2.1.1.307; ElmMIII. Cat No: EXWM-1915. | |
| 8-demethyl-8-(2-methoxy-α-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase | The enzyme from the bacterium Streptomyces olivaceus is involved in the biosynthesis of the polyketide elloramycin. Group: Enzymes. Synonyms: ElmMII. Enzyme Commission Number: EC 2.1.1.306. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1914; 8-demethyl-8-(2-methoxy-α-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase; EC 2.1.1.306; ElmMII. Cat No: EXWM-1914. | |
| 8-demethyl-8-α-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase | The enzyme from the bacterium Streptomyces olivaceus is involved in the biosynthesis of the polyketide elloramycin. Group: Enzymes. Synonyms: ElmMI. Enzyme Commission Number: EC 2.1.1.305. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1913; 8-demethyl-8-α-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase; EC 2.1.1.305; ElmMI. Cat No: EXWM-1913. | |
| acetoacetyl-CoA synthase | The enzyme from the soil bacterium Streptomyces sp. CL190 produces acetoacetyl-CoA to be used for mevalonate production via the mevalonate pathway.Unlike the homologous EC 2.3.1.180 (β-ketoacyl-[acyl-carrier-protein] synthase III), this enzyme does not accept malonyl-[acyl-carrier-protein] as a substrate. Group: Enzymes. Synonyms: NphT7. Enzyme Commission Number: EC 2.3.1.194. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2137; acetoacetyl-CoA synthase; EC 2.3.1.194; NphT7. Cat No: EXWM-2137. | |
| aclacinomycin-T 2-deoxy-L-fucose transferase | The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro. Group: Enzymes. Synonyms: AknK. Enzyme Commission Number: EC 2.4.1.327. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2564; aclacinomycin-T 2-deoxy-L-fucose transferase; EC 2.4.1.327; AknK. Cat No: EXWM-2564. | |
| Aclarubicin A | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Synonyms: 11-Dioxo-4-((2,3,6-trideoxy-4-o-(2,6-dideoxy-4-o-((2r-trans)-tetrahydro-6-met;1-naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6;(1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S). Grades: ≥95%. CAS No. 57576-44-0. Molecular formula: C42H53NO15. Mole weight: 811.88. |  |
| Aclarubicin hydrochloride | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Synonyms: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grades: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33. | |
| aklanonic acid methyltransferase | The enzyme from the Gram-positive bacterium Streptomyces sp. C5 is involved in the biosynthesis of the anthracycline daunorubicin. Group: Enzymes. Synonyms: DauC; AAMT. Enzyme Commission Number: EC 2.1.1.288. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1895; aklanonic acid methyltransferase; EC 2.1.1.288; DauC; AAMT. Cat No: EXWM-1895. | |
| aklaviketone reductase | The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin. Group: Enzymes. Synonyms: dauE (gene name); aknU (gene name). Enzyme Commission Number: EC 1.1.1.362. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0279; aklaviketone reductase; EC 1.1.1.362; dauE (gene name); aknU (gene name). Cat No: EXWM-0279. | |
| Aklavin | It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Synonyms: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60. | |
| aklavinone 7-L-rhodosaminyltransferase | Isolated from the bacterium Streptomyces galilaeus. Forms a complex with its accessory protein AknT, and has very low activity in its absence. The enzyme can also use dTDP-2-deoxy-β-L-fucose. Involved in the biosynthesis of other aclacinomycins. Group: Enzymes. Synonyms: AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Enzyme Commission Number: EC 2.4.1.326. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2563; aklavinone 7-L-rhodosaminyltransferase; EC 2.4.1.326; AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Cat No: EXWM-2563. | |
| albonoursin synthase | A flavoprotein from the bacterium Streptomyces noursei. The enzyme can also oxidize several other cyclo dipeptides, the best being cyclo(L-tryptophyl-L-tryptophyl) and cyclo(L-phenylalanyl-L-phenylalanyl). Group: Enzymes. Synonyms: cyclo(dipeptide):oxygen oxidoreductase; cyclic dipeptide oxidase; AlbA. Enzyme Commission Number: EC 1.3.3.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1374; albonoursin synthase; EC 1.3.3.13; cyclo(dipeptide):oxygen oxidoreductase; cyclic dipeptide oxidase; AlbA. Cat No: EXWM-1374. | |
| Anthelvencin A | It is produced by the strain of Streptomyces venezuelae. It has the activity of resisting gram positive bacterium, negative bacterium, mycobacterium, yeast and ringworm, has the inhibition to vaccinia virus, dysentery amoeba, and has the effect of repelling nematode in mice. Synonyms: (4S)-(+)-Anthelvencin A; NSC624528; (S)-Anthelvencin A; LS-20251; {4-[((5S)-2-amino(1-pyrrolin-5-yl))carbonylamino]pyrrol-2-yl}-N-{5-[N-(2-amidinoethyl)carbamoyl]-1-methylpyrrol-3-yl}carboxamide. CAS No. 58616-25-4. Molecular formula: C19H25N9O3. Mole weight: 427.46. | |
| Anthelvencin B | It is produced by the strain of Streptomyces venezuelae. It has the activity of resisting gram positive bacterium, negative bacterium, mycobacterium, yeast and ringworm, has the inhibition to vaccinia virus, dysentery amoeba, and has the effect of repelling nematode in mice. Synonyms: Anthelvencine B; DTXSID30911498; N-[5-({5-[(3-Amino-3-iminopropyl)carbamoyl]-1-methyl-1H-pyrrol-3-yl}carbamoyl)-1-methyl-1H-pyrrol-3-yl]-5-iminopyrrolidine-2-carboximidic acid. CAS No. 11011-26-0. Molecular formula: C20H27N9O3. Mole weight: 441.49. | |
| β-(isoxazolin-5-on-4-yl)-L-alanine synthase | 3-(5-Oxoisoxazolin-4-yl)-L-alanine is an antifungal antibiotic produced by the bacterium Streptomyces platensis. The enzymes from the plants Lathyrus odoratus (sweet pea), L. sativus (grass pea) and Citrullus vulgaris (watermelon) that catalyse EC 2.5.1.118 (β-(isoxazolin-5-on-2-yl)-L-alanine synthase) also catalyse this reaction in vitro, but not in vivo. Closely related and possibly identical to EC 2.5.1.47, cysteine synthase, and EC 2.5.1.51, β-pyrazolylalanine synthase. Group: Enzymes. Enzyme Commission Number: EC 2.5.1.119. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2735; β-(isoxazolin-5-on-4-yl)-L-alanine synthase; EC 2.5.1.119. Cat No: EXWM-2735. | |
| β-methylindole-3-pyruvate reductase | The enzyme, characterized from the bacterium Streptomyces griseus, participates in the biosynthesis of indolmycin, an antibacterial drug that inhibits the bacterial tryptophan-tRNA ligase (EC 6.1.1.2). Group: Enzymes. Synonyms: ind2 (gene name). Enzyme Commission Number: EC 1.1.1.397. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0317; β-methylindole-3-pyruvate reductase; EC 1.1.1.397; ind2 (gene name). Cat No: EXWM-0317. | |
| β-methylphenylalanine transaminase | Requires pyridoxal phosphate. Isolated from the bacterium Streptomyces hygroscopicus NRRL3085. It is involved in the biosynthesis of the glycopeptide antibiotic mannopeptimycin. Group: Enzymes. Synonyms: TyrB. Enzyme Commission Number: EC 2.6.1.107. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2847; β-methylphenylalanine transaminase; EC 2.6.1.107; TyrB. Cat No: EXWM-2847. | |
| Bicyclomycin | Bicyclomycin is a diketopiperazine antibiotics produced by Streptomyces Sapporonesis WS-4545 and Str. aizunensis. Bicyclomycin (Bicozamycin) is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium. Synonyms: Bicozamycin; Aizumycin; Bacteron; Bicozamicina. Grades: >98%. CAS No. 38129-37-2. Molecular formula: C12H18N2O7. Mole weight: 302.28. | |
| biflaviolin synthase | This cytochrome-P-450 enzyme, from the soil-dwelling bacterium Streptomyces coelicolor A3(2), catalyses a phenol oxidation C-C coupling reaction, which results in the polymerization of flaviolin to form biflaviolin or triflaviolin without the incorporation of oxygen into the product. The products are highly conjugated pigments that protect the bacterium from the deleterious effects of UV irradiation. Group: Enzymes. Synonyms: CYP158A2; CYP 158A2; cytochrome P450 158A2. Enzyme Commission Number: EC 1.14.21.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1028; biflaviolin synthase; EC 1.14.21.7; CYP158A2; CYP 158A2; cytochrome P450 158A2. Cat No: EXWM-1028. | |
| Bleomycin A2 | It is one of two components found in the glycopeptide antineoplastic antibiotic Bleomycin sulfate. Bleomycin sulfate is a chemotherapeutic agent used for the treatment of hodgkins lymphoma. It is isolated from the bacterium Streptomyces verticillus. Synonyms: Bleomycin a2; Bleomycinamide, N1-[3-(dimethylsulfonio)propyl]-; Bleogin; N1-[3- (Dimethylsulfonio) propyl]bleomycinamide; Pingyangmycin A2; Zhengguangmycin A2. Grades: ≥95.0%. CAS No. 11116-31-7. Molecular formula: C55H84N17O21S3. Mole weight: 1415.55. | |
| C7-cyclitol 7-kinase | The enzyme, characterized from the bacterium Streptomyces hygroscopicus var. jinggangensis, is involved in the biosynthesis of the antifungal agent validamycin A. Group: Enzymes. Synonyms: valC (gene name); vldC (gene name). Enzyme Commission Number: EC 2.7.1.214. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3050; C7-cyclitol 7-kinase; EC 2.7.1.214; valC (gene name); vldC (gene name). Cat No: EXWM-3050. | |
| Carbazomycin D | Carbazomycin D is a bacterial metabolite originally isolated from Streptomyces and it has diverse biological activities. It is active against the fungi T. asteroides and T. mentagrophytes (MIC = 100 μg/ml for both) and the bacterium M. tuberculosis (IC50 = 25 μg/ml). Carbazomycin D is also cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 21.3, 33.2, 12.9, and 34.3 μg/ml, respectively). Synonyms: 3,4,6-Trimethoxy-1,2-dimethylcarbazole; ACMC-20cjqw. Grades: >95% by HPLC. CAS No. 108073-63-8. Molecular formula: C17H19NO3. Mole weight: 285.34. | |
| cembrene A synthase | Requires Mg2+. Isolated from the bacterium Streptomyces sp. SANK 60404. This trifunctional enzyme, which contains a [4Fe-4S] cluster, also produces (R)-nephthenol and (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol. See EC 4.2.3.149, nephthenol synthase and EC 4.2.3.151, pentamethylcyclopentadecatrienol synthase. Group: Enzymes. Synonyms: DtcycB (gene name). Enzyme Commission Number: EC 4.2.3.150. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5165; cembrene A synthase; EC 4.2.3.150; DtcycB (gene name). Cat No: EXWM-5165. | |
| cembrene C synthase | Requires Mg2+. Isolated from the bacterium Streptomyces sp. SANK 60404. This bifunctional enzyme also produces (R)-nephthenol. See EC 4.2.3.149, nephthenol synthase. Group: Enzymes. Synonyms: DtcycA (gene name). Enzyme Commission Number: EC 4.2.3.148. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5162; cembrene C synthase; EC 4.2.3.148; DtcycA (gene name). Cat No: EXWM-5162. | |
| Chloramphenicol (HRP) | Chloramphenicol is a broad spectrum antibiotic isolated from the soil bacterium Streptomyces venezuela. It is bacteriostatic in action and inhibits bacterial protein synthesis by binding to the ribosomal 50S subunit. Chloramphenicol has been used to treat a wide range of human and animal conditions. Chloramphenicol is well absorbed orally and is distributed widely in body fluids. It is metabolized in the liver to the inactive glucuronide. Both chloramphenicol and the glucuronide metabolite are excreted in urine. Metabolism studies in food producing animals demonstrated numerous differences in metabolic profiles between bovine, porcine and poultry species, although the parent drug was the major metabolite identified in muscle for all species. Group: Biochemicals. Grades: Purified. Pack Sizes: 500ul. US Biological Life Sciences. | Worldwide |
| cyclo(L-leucyl-L-phenylalanyl) synthase | The reaction proceeds following a ping-pong mechanism forming a covalent intermediate between an active site serine and the L-phenylalanine residue. The protein, found in the bacterium Streptomyces noursei, also forms cyclo(L-phenylalanyl-L-phenylalanyl), cyclo(L-methionyl-L-phenylalanyl), cyclo(L-phenylalanyl-L-tyrosyl) and cyclo(L-methionyl-L-tyrosyl). Group: Enzymes. Synonyms: AlbC; cFL synthase. Enzyme Commission Number: EC 2.3.2.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2294; cyclo(L-leucyl-L-phenylalanyl) synthase; EC 2.3.2.20; AlbC; cFL synthase. Cat No: EXWM-2294. | |
| cyclooctat-9-en-7-ol synthase | Requires Mg2+. Isolated from the bacterium Streptomyces melanosporofaciens, where it is part of the biosynthesis of cyclooctatin, a potent inhibitor of lysophospholipase. Group: Enzymes. Synonyms: cetB2. Enzyme Commission Number: EC 4.2.3.146. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5160; cyclooctat-9-en-7-ol synthase; EC 4.2.3.146; cetB2. Cat No: EXWM-5160. | |
| cypemycin cysteine dehydrogenase (decarboxylating) | Cypemycin, isolated from the bacterium Streptomyces sp. OH-4156, is a peptide antibiotic, member of the linaridins, a class of posttranslationally modified ribosomally synthesized peptides. The enzyme decarboxylates and reduces the C-terminal L-cysteine residue, producing a reactive ethenethiol group that reacts with a dethiolated cysteine upstream to form an aminovinyl-methyl-cysteine loop that is important for the antibiotic activity of the mature peptide. Group: Enzymes. Synonyms: cypemycin decarboxylase; CypD. Enzyme Commission Number: EC 1.3.99.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1436; cypemycin cysteine dehydrogenase (decarboxylating); EC 1.3.99.36; cypemycin decarboxylase; CypD. Cat No: EXWM-1436. | |
| cypemycin N-terminal methyltransferase | The enzyme, isolated from the bacterium Streptomyces sp. OH-4156, can methylate a variety of linear oligopeptides, cyclic peptides such as nisin and haloduracin, and the ε-amino group of lysine. Cypemycin is a peptide antibiotic, a member of the linaridins, a class of posttranslationally modified ribosomally synthesized peptides. Group: Enzymes. Synonyms: CypM. Enzyme Commission Number: EC 2.1.1.301. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1909; cypemycin N-terminal methyltransferase; EC 2.1.1.301; CypM. Cat No: EXWM-1909. | |
| demethylmacrocin O-methyltransferase | Requires Mg2+. The enzyme, isolated from the bacterium Streptomyces fradiae, is involved in the biosynthesis of the macrolide antibiotic tylosin. The 2-hydroxy group of a 6-deoxy-D-allose moiety in demethylmacrocin acts as the methyl acceptor. Also acts on demethyllactenocin, giving lactenocin. Not identical with EC 2.1.1.101 macrocin O-methyltransferase. Group: Enzymes. Synonyms: demethylmacrocin methyltransferase; DMOMT. Enzyme Commission Number: EC 2.1.1.102. CAS No. 120313-64-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1700; demethylmacrocin O-methyltransferase; EC 2.1.1.102; 120313-64-6; demethylmacrocin methyltransferase; DMOMT. Cat No: EXWM-1700. | |
| deoxynogalonate monooxygenase | The enzyme, characterized from the bacterium Streptomyces nogalater, is involved in the biosynthesis of the aromatic polyketide nogalamycin. Group: Enzymes. Synonyms: SnoaB (gene name); 12-deoxynogalonic acid oxidoreductase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate oxidase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate monooxygenase; deoxynogalonate oxidoreductase. Enzyme Commission Number: EC 1.13.12.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0615; deoxynogalonate monooxygenase; EC 1.13.12.22; SnoaB (gene name); 12-deoxynogalonic acid oxidoreductase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate oxidase; [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate monooxygenase; deoxynogalonate oxidoreductase. Cat No: EXWM-0615. | |
| Destomycin A | Destomycin A is produced by the strain of Streptomyces rimofaciens. It has anti-gram positive bacterium, negative bacterium and fungus activity, adding Destomycin A in a pig feed, it has drive ascaris action. Synonyms: Destonate 20; NSC 96877; 2,3-O-(6-(1-Amino-2-hydroxyethyl)-3,4,5-trihydroxytetrahydropyran-2-yliden)-(3-amino-5-methylamino-3,4,5-tridesoxy-mesoinosit-1-yl)-beta-D-talopyranosid. Grades: 98%. CAS No. 14918-35-5. Molecular formula: C20H37N3O13. Mole weight: 527.52. | |
| Destomycin B | Destomycin B is produced by the strain of Streptomyces rimofaciens. It has anti-gram positive bacterium, negative bacterium and fungus activity, adding Destomycin B in a pig feed, it has drive ascaris action. Synonyms: A 16316 C; D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-O-beta-D-talopyranosyl-(1-5)-2-deoxy-N,N'-dimethyl-. CAS No. 11005-98-4. Molecular formula: C21H39N3O13. Mole weight: 541.55. | |
| desulfo-A47934 sulfotransferase | The enzyme from the bacterium Streptomyces toyocaensis catalyses the final step in the biosynthesis of the glycopeptide antibiotic A47934, a naturally occuring antibiotic of the vancomycin group. Group: Enzymes. Synonyms: StaL. Enzyme Commission Number: EC 2.8.2.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3396; desulfo-A47934 sulfotransferase; EC 2.8.2.36; StaL. Cat No: EXWM-3396. | |
| Distamycin A | It is produced by the strain of Streptomyces distallicus NCIB 8936. It has the activity against gram-positive bacterium, mycobacterium, dermatophyte and Trichophyte. It has inhibitory effects on solid tumors such as Epstein-Barr ascites carcinoma, sarcoma 180, Walker 258, oberling-Guerin osteoma, and also inhibits vaccinosis virus, herpes simplex virus, adenovirus, and mouse hepatitis virus in cell culture. Synonyms: Distamycin; Distamycin-3; stallimycin; Herperetin; DST-A; Estalimicina; Stallimicina; Stallimycinum; 2N-(3,3-aminoiminopropyl)-4-[4-(4-formamido-1-methyl-1H-2-pyrrolylcarboxamido)-1-methyl-1H-2-pyrrolylcarboxamido]-1-methyl-1H-2-pyrrolecarboxamide. Grades: 95%. CAS No. 636-47-5. Molecular formula: C22H27N9O4. Mole weight: 481.51. | |
| Doxorubicin, Hydrochloride (Adriacin, Adriblastina, Adriamycin, Caelyx) | The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. Group: Biochemicals. Alternative Names: Adriacin, Adriblastina, Adriamycin, Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase | The enzyme is involved in the synthesis of dTDP-D-ravidosamine, the amino sugar moiety of the antibiotic ravidomycin V, which is produced by the bacterium Streptomyces ravidus. Group: Enzymes. Synonyms: RavNMT. Enzyme Commission Number: EC 2.1.1.236. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1839; dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase; EC 2.1.1.236; RavNMT. Cat No: EXWM-1839. | |
| dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase | The enzyme is involved in the biosynthesis of mycaminose, an essential structural component of the macrolide antibiotic tylosin, which is produced by the bacterium Streptomyces fradiae. Group: Enzymes. Synonyms: TylM1. Enzyme Commission Number: EC 2.1.1.235. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1838; dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase; EC 2.1.1.235; TylM1. Cat No: EXWM-1838. | |
| epi-isozizaene 5-monooxygenase | This cytochrome-P-450 enzyme, from the soil-dwelling bacterium Streptomyces coelicolor A3(2), catalyses two sequential allylic oxidation reactions. The substrate epi-isozizaene, which is formed by the action of EC 4.2.3.37, epi-isozizaene synthase, is first oxidized to yield the epimeric intermediates (5R)-albaflavenol and (5S)-albaflavenol, which can be further oxidized to yield the sesquiterpenoid antibiotic albaflavenone. Group: Enzymes. Synonyms: CYP170A1. Enzyme Commission Number: EC 1.14.13.106. CAS No. 1207718-51-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0705; epi-isozizaene 5-monooxygenase; EC 1.14.13.106; 1207718-51-1; CYP170A1. Cat No: EXWM-0705. | |
| epi-isozizaene synthase | Requires Mg2+ for activity. The displacement of the diphosphate group of farnesyl diphosphate occurs with retention of configuration. In the soil-dwelling bacterium Streptomyces coelicolor A3(2), the product of this reaction is used by EC 1.14.13.106, epi-isozizaene 5-monooxygenase, to produce the sesquiterpene antibiotic albaflavenone. Group: Enzymes. Synonyms: SCO5222 protein. Enzyme Commission Number: EC 4.2.3.37. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5195; epi-isozizaene synthase; EC 4.2.3.37; SCO5222 protein. Cat No: EXWM-5195. | |
| flaviolin linalyltransferase | Does not require Mg2+ or any other metal ions. Isolated from the bacterium Streptomyces cinnamonensis. In vitro the enzyme also forms traces of 3-geranylflaviolin. Group: Enzymes. Synonyms: Fnq26. Enzyme Commission Number: EC 2.5.1.123. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2739; flaviolin linalyltransferase; EC 2.5.1.123; Fnq26. Cat No: EXWM-2739. | |
| fluoroacetyl-CoA thioesterase | Fluoroacetate is extremely toxic. It reacts with CoA to form fluoroacetyl-CoA, which substitutes for acetyl CoA and reacts with EC 2.3.3.1 (citrate synthase) to produce fluorocitrate, a metabolite of which binds very tightly to EC 4.2.1.3 (aconitase) and halts the TCA cycle. This enzyme hydrolyses fluoroacetyl-CoA before it can react with citrate synthase, and thus confers fluoroacetate resistance on the organisms that produce it. It has been described in the poisonous plant Dichapetalum cymosum and the bacterium Streptomyces cattleya, both of which are fluoroacetate producers. Group: Enzymes. Enzyme Commission Number: EC 3.1.2.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3562; fluoroacetyl-CoA thioesterase; EC 3.1.2.29. Cat No: EXWM-3562. | |
| grixazone synthase | A type 3 multi copper protein. The enzyme, isolated from the bacterium Streptomyces griseus, catalyses an 8 electron oxidation. Activation of the enzyme requires a copper chaperone (GriE). It also acts on 3-amino-4-hydroxybenzaldehyde, giving grixazone A. The second aldehyde group is presumably lost as formate. The enzyme also catalyses the reaction of EC 1.10.3.4 o-aminophenol oxidase. Group: Enzymes. Synonyms: GriF. Enzyme Commission Number: EC 1.10.3.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0481; grixazone synthase; EC 1.10.3.15; GriF. Cat No: EXWM-0481. | |
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