Bendamustine Suppliers USA
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Product | Description | |
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Bendamustine Quick inquiry Where to buy Suppliers range | Bendamustine. Group: Main Products. Alternative Names: 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;Bendamustine;4-(5-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid;1H-BenziMidazole-2-butanoicacid, 5-[bis(2-chloroethyl)aMino]-1-Methyl-. Grades: 95%. CAS No. 16506-27-7. Molecular formula: C16H21Cl2N3O2. Mole weight: 358.26. IUPAC Name: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoicacid. Exact Mass: 357.10100. Boiling Point: 585.2ºC at 760 mmHg. Density: 1.31 g/cm3. SMILES: CN1C2=C (C=C (C=C2)N (CCCl)CCCl)N=C1CCCC (=O)O. InChIKey: YTKUWDBFDASYHO-UHFFFAOYSA-N. | |
Bendamustine Quick inquiry Where to buy Suppliers range | Bendamustine, a lbenzimidazol derivative, has been found to be an alkylating agent that acts through restraining DNA synthesis so that could be useful as an antineoplastic agent. Uses: Antineoplastic; bendamustine hydrochloride. Synonyms: 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;Bendamustine. Grades: 98%. CAS No. 16506-27-7. Molecular formula: C16H21Cl2N3O2. Mole weight: 358.26. | |
Bendamustine bis-mercapturic acid Quick inquiry Where to buy Suppliers range | Bendamustine bis-mercapturic acid. Group: Biochemicals. Alternative Names: 5- [Bis [2- [ [ (2R) -2- (acetylamino) -2-carboxyethyl] thio] ethyl] amino] -1-methyl-1H-benzimidazole-2-butanoic acid. Grades: Highly Purified. CAS No. 956344-34-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H37N5O8S2. US Biological Life Sciences. | Worldwide |
Bendamustine Chloro Dimer Impurity Quick inquiry Where to buy Suppliers range | Bendamustine Chloro Dimer Impurity is an impurity of Bendamustine, a chemotherapy medication indicated for the treatment of chronic lymphocytic leukemia, multiple myeloma, and non-Hodgkin's lymphoma. Synonyms: Bendamustine Dimer Impurity; 5-[bis(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 2-[[2-(3-Carboxypropyl)-1-methyl-1H-benzimidazol-5-yl](2-chloroethyl)amino]ethyl Ester. Grades: > 95%. CAS No. 1228551-91-4. Molecular formula: C32H41Cl3N6O4. Mole weight: 680.08. | |
Bendamustine-d5 (major) Hydrochloride (5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid-d5 Hydrochloride; Cytostasan-d5; Ribomustin-d5; Treanda-d5) Quick inquiry Where to buy Suppliers range | Betamustine acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450. >95% of the drug is bound to protein - primarily albumin. Only free bendamustine is active. Elimination is biphasic with a half-life of 6-10 minutes and a terminal half-life of approximately 30 minutes. It is eliminated primarily by the renal route. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid-d5 Hydrochloride; Cytostasan-d5; Ribomustin-d5; Treanda-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Bendamustine Deschloro Dimer Impurity Quick inquiry Where to buy Suppliers range | Bendamustine Deschloro Dimer Impurity is an impurity of Bendamustine. Synonyms: 4-[5-((2-((4-(5-(Bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanic Acid. Grades: > 95%. CAS No. 1391052-61-1. Molecular formula: C32H44N6O7. Mole weight: 624.74. | |
Bendamustine Desmethyl Impurity Quick inquiry Where to buy Suppliers range | Bendamustine Desmethyl Impurity is an impurity of Bendamustine, an anticancer drug used to treat chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Synonyms: Bendamustine Desmethyl Impurity; Desmethyl Bendamustine Hydrochloride; 4-[6-[Bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]butanoic acid; hydrochloride; FT-0696961. Grades: > 95%. CAS No. 31349-38-9. Molecular formula: C15H19Cl2N3O2. Mole weight: 344.24. | |
Bendamustine Dihydroxy Impurity Quick inquiry Where to buy Suppliers range | Bendamustine Dihydroxy Impurity is an impurity of Bendamustine. Synonyms: 5-[Bis(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid; Dihydroxy Bendamustine. Grades: > 95%. CAS No. 109882-30-6. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
Bendamustine Dimer 2-Allyl Ester Quick inquiry Where to buy Suppliers range | Bendamustine Dimer 2-Allyl Ester is an dimer impurity of Bendamustine (B132500), an anticancer drug. Group: Biochemicals. Alternative Names: 4- (5- ( (2- ( (4- (5- (bis (2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl) (2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate Allyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Bendamustine Ether Impurity Quick inquiry Where to buy Suppliers range | Bendamustine Ether Impurity is an dimer impurity of Bendamustine. Synonyms: 4-(1-Methyl-5-morpholino-1H-benzo[d]imidazol-2-yl)butanoic Acid; 1-Methyl-5-(4-morpholinyl)-1H-benzimidazole-2-butanoic Acid. Grades: > 95%. CAS No. 1228552-02-0. Molecular formula: C16H21N3O3. Mole weight: 303.36. | |
Bendamustine hydrochloride Quick inquiry Where to buy Suppliers range | Bendamustine hydrochloride. Group: Main Products. Alternative Names: bendamustine hydrochloride;BENDAMUSTIN HYDROCHLORIDE;CYTOSTASAN;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride ; 1- methyl -5-bis (2-chloroethyl) amino-2-benzimidazolinebutryricaci hydrochlor; gamma (1- methyl -5-bis (beta-chloraethyl) aminobenzimidazoyl-2) buttersaeure hydro; BENDAMUSTINE HCL. Grades: 98%+. CAS No. 3543-75-7. Product ID: ACM3543757. Molecular formula: C16H22Cl3N3O2. Mole weight: 394.72. IUPAC Name: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoicacid;hydrochloride. Appearance: powder. Melting Point: 149-151°C. | |
Bendamustine hydrochloride Quick inquiry Where to buy Suppliers range | Bendamustine hydrochloride. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride; Cytostasan; Ribomustin. Grades: Highly Purified. CAS No. 3543-75-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H22Cl3N3O2. US Biological Life Sciences. | Worldwide |
BendaMustine Hydrochloride Quick inquiry Where to buy Suppliers range | Bendamustine hydrochloride monotherapy or combination therapy has been designated by European and American clinical guidelines as a first - or second-line treatment option for a variety of hematological malignancies. Uses: Used for research and manufacturing. Group: Other Active Pharmaceutical Ingredients. CAS No. 3543-75-7. Product ID: PAP-0094. Appearance: Powder. | |
BENDAMUSTINE HYDROCHLORIDE Quick inquiry Where to buy Suppliers range | BENDAMUSTINE HYDROCHLORIDE. CAS No. 3543-75-7. | |
Bendamustine Hydrochloride (5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride, Cytostasan, Ribomustin, Treanda) Quick inquiry Where to buy Suppliers range | Used as an anticancer drug. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride; Cytostasan; Ribomustin; Treanda. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Bendamustine Impurity A Quick inquiry Where to buy Suppliers range | Bendamustine Impurity A is an impurity of Bendamustine, a drug for treating formidable non-Hodgkin lymphoma and the enduring chronic lymphocytic leukemia. Synonyms: 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid; Hydroxy BendaMustine. Grades: > 95%. CAS No. 109882-27-1. Molecular formula: C16H22ClN3O3. Mole weight: 339.83. | |
Bendamustine Impurity C Quick inquiry Where to buy Suppliers range | Bendamustine Impurity C is an impurity in commercial preparation of Bendamustine. Synonyms: Bendamustine Isopropyl Ester; 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Isopropyl Ester; Isopropyl 4-(5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl) butanoate. Grades: > 95%. CAS No. 1313020-25-5. Molecular formula: C19H27Cl2N3O2. Mole weight: 400.35. | |
Bendamustine Impurity D Quick inquiry Where to buy Suppliers range | Bendamustine Impurity D is a degradation production of Bendamustine. Synonyms: 4-(6-(2-Chloroethyl)-3-methyl-3, 6, 7, 8-tetrahydroimidazo[4', 5':5, 6]benzo[1, 2-b][1, 4]thiazin-2-yl)butanoic Acid; 6-(2-Chloroethyl)-3,6,7,8-tetrahydro-3-methyl-Imidazo[4,5-h][1,4]benzothiazine-2-butanoic Acid; 4-(7,8-Dihydro-6-(2-Chloroethylamino)-3-methyl-1,4. Grades: > 95%. CAS No. 191939-34-1. Molecular formula: C16H20ClN3O2S. Mole weight: 353.87. | |
Bendamustine Related Impurity 1 Quick inquiry Where to buy Suppliers range | Cas No. 3543-74-6. | |
Bendamustine Related Impurity 4 Quick inquiry Where to buy Suppliers range | Bendamustine Related Impurity 4 is an impurity of bendamustine, a chemotherapy drug used for the therapy of non-Hodgkin lymphoma and chronic lymphocytic leukemia. Synonyms: N1-Methylbenzene-1,2,4-triaMine; 1,2,4-BenzenetriaMine, N1-Methyl-. Grades: > 95%. CAS No. 60651-29-8. Molecular formula: C7H11N3. Mole weight: 137.19. | |
Bendamustine Related Impurity 5 Quick inquiry Where to buy Suppliers range | Bendamustine Related Impurity 5 is an impurity of bendamustine, a novel pharmaceuticals designed to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma. Synonyms: 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Ethyl Ester. Grades: > 95%. CAS No. 898224-95-8. Molecular formula: C18H26ClN3O3. Mole weight: 367.88. | |
2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride Quick inquiry Where to buy Suppliers range | 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride is a derivative of Bendamustine Hydrochloride (B132500), a compound used as a chemotherapy drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1793059-58-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C19H29Cl3N4O2, Molecular Weight: 451.82. US Biological Life Sciences. | Worldwide |
2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride-D10 Quick inquiry Where to buy Suppliers range | 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride-D10 is a labelled analogue of 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride (D289355). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C19H19D10Cl3N4O2, Molecular Weight: 461.88. US Biological Life Sciences. | Worldwide |
Deschloroethyl Bendamustine Hydrochloride Quick inquiry Where to buy Suppliers range | Deschloroethyl Bendamustine Hydrochloride. Group: Biochemicals. Alternative Names: 5-[(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid; 4-[5-(2-Chloroethylamino)-1-methylbenzimidazol-2-yl]butanoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C14H19Cl2N3O2, Molecular Weight: 332.23. US Biological Life Sciences. | Worldwide |
Desmethyl Bendamustine Hydrochloride Quick inquiry Where to buy Suppliers range | Desmethyl Bendamustine Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 31349-38-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
Hydroxy bendamustine Quick inquiry Where to buy Suppliers range | Hydroxy bendamustine. Group: Biochemicals. Alternative Names: 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid. Grades: Highly Purified. CAS No. 109882-27-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H22ClN3O3. US Biological Life Sciences. | Worldwide |
N-desmethyl bendamustine Quick inquiry Where to buy Suppliers range | N-desmethyl bendamustine is an impurity of bendamustine, a DNA alkylating agent used for the treatment of chronic lymphocytic leukemia (CLL). Synonyms: nor-Bendamustine; 4-[6-[bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]butanoic acid. Grades: ≥95%. CAS No. 41515-13-3. Molecular formula: C15H19Cl2N3O2. Mole weight: 344.24. | |
1,3-Bis[1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane Quick inquiry Where to buy Suppliers range | 1,3-Bis[1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane is an impurity of the drug Bendamustine (B132500). Bendamustine is used as an anticancer drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 914626-65-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H18N6O4, Molecular Weight: 394.38. US Biological Life Sciences. | Worldwide |
1-Methyl-5-amino-1H-benzimidazole-2-butanoic Acid Ethyl Ester-d3 Quick inquiry Where to buy Suppliers range | Labeled Bendamustine. Group: Biochemicals. Alternative Names: 5-Amino-1-methyl-. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
1-Methyl-5-nitro-1H-benzimidazole-2-butanoic Acid Ethyl Ester-d3 Quick inquiry Where to buy Suppliers range | Labeled Bendamustine. Group: Biochemicals. Alternative Names: 1-Methyl-5-nitro-2-benzimidazolebutyric Acid. Grades: Highly Purified. CAS No. unlabelled:3543-72-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
2,2'-(1,3-Propanediyl)bis[1-methyl-1H-benzimidazol-5-amine Quick inquiry Where to buy Suppliers range | 2,2'-(1,3-Propanediyl)bis[1-methyl-1H-benzimidazol-5-amine is an impurity of the drug Bendamustine (B132500). Bendamustine is used as an anticancer drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 847588-86-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H22N6, Molecular Weight: 333.42. US Biological Life Sciences. | Worldwide |
4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid Quick inquiry Where to buy Suppliers range | 4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid is an intermediate in the synthesis of Bendamustine (B132500), an anticancer drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid tert-Butyl Ester Quick inquiry Where to buy Suppliers range | 4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid tert-Butyl Ester is a protected intermediate in the synthesis of Bendamustine (B132500), an anticancer drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester Quick inquiry Where to buy Suppliers range | 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester. Group: Biochemicals. Alternative Names: Bendamustine Impurity. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C19H28ClN3O3, Molecular Weight: 381.9. US Biological Life Sciences. | Worldwide |
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | Bendamustine (B132500) impurity. Group: Biochemicals. Alternative Names: Bendamustine Impurity. Grades: Highly Purified. CAS No. 898224-95-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
5- [ (2-tert-Butyldi methyl silyloxyethyl) (2-chloroethyl) amino] -1- methyl -1H-benzimidazole-2-butanoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | Protected Bendamustine (B132500) impurity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Methyl Ester. Group: Biochemicals. Alternative Names: Bendamustine USP Impurity. Grades: Highly Purified. CAS No. 109882-25-9. Pack Sizes: 10mg. Molecular Formula: C17H23Cl2N3O2, Molecular Weight: 372.29. US Biological Life Sciences. | Worldwide |
AZD3965 Quick inquiry Where to buy Suppliers range | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Synonyms: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. Grades: >98%. CAS No. 1448671-31-5. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. | |
EDO-S101 Quick inquiry Where to buy Suppliers range | EDO-S101 is a pan HDAC inhibitor (IC50 = 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3, respectively). EDO-S101 is a first-in-class fusion molecule that combines DNA damaging effect of bendamustine with the pan-HDACi vorinostat. Synonyms: 7-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]-N-hydroxyheptanamide; EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride. CAS No. 1236199-60-2. Molecular formula: C19H28Cl2N4O2. Mole weight: 415.36. | |
Glutaric Acid-2-methylamino-5-nitromonoanilide-d3 Quick inquiry Where to buy Suppliers range | Intermediate in the production of labeled Bendamustine. Group: Biochemicals. Alternative Names: 2'-(Methylamino)-5'-nitro-glutaranilic Acid-d3; 5-[[2-(Methylamino)-5-nitrophenyl]amino]-5-oxo-pentanoic Acid-d3. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Polatuzumab Quick inquiry Where to buy Suppliers range | Polatuzumab is a monoclonal antibody directed against CD79b, which is ubiquitously expressed on the surface of malignant B cells. Polatuzumab can be used in the synthesis of polatuzumab vedotin, an ADC indicated in combination with bendamustine and a rituximab product for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). CAS No. 2279068-37-8. |