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| Product | Description | |
|---|---|---|
| Bendamustine | Bendamustine, a lbenzimidazol derivative, has been found to be an alkylating agent that acts through restraining DNA synthesis so that could be useful as an antineoplastic agent. Uses: Antineoplastic; bendamustine hydrochloride. Synonyms: 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;Bendamustine. Grades: 98%. CAS No. 16506-27-7. Molecular formula: C16H21Cl2N3O2. Mole weight: 358.26. |  |
| Bendamustine | Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDX-105 free base. CAS No. 16506-27-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13567. |  |
| Bendamustine bis-mercapturic acid | Bendamustine bis-mercapturic acid. Group: Biochemicals. Alternative Names: 5- [Bis [2- [ [ (2R) -2- (acetylamino) -2-carboxyethyl] thio] ethyl] amino] -1-methyl-1H-benzimidazole-2-butanoic acid. Grades: Highly Purified. CAS No. 956344-34-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H37N5O8S2. US Biological Life Sciences. |  Worldwide |
| Bendamustine Chloro Dimer Impurity | Bendamustine Chloro Dimer Impurity is an impurity of Bendamustine, a chemotherapy medication indicated for the treatment of chronic lymphocytic leukemia, multiple myeloma, and non-Hodgkin's lymphoma. Synonyms: Bendamustine Dimer Impurity; 5-[bis(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 2-[[2-(3-Carboxypropyl)-1-methyl-1H-benzimidazol-5-yl](2-chloroethyl)amino]ethyl Ester. Grades: > 95%. CAS No. 1228551-91-4. Molecular formula: C32H41Cl3N6O4. Mole weight: 680.08. | |
| Bendamustine-d5 (major) Hydrochloride (5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid-d5 Hydrochloride; Cytostasan-d5; Ribomustin-d5; Treanda-d5) | Betamustine acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450. >95% of the drug is bound to protein - primarily albumin. Only free bendamustine is active. Elimination is biphasic with a half-life of 6-10 minutes and a terminal half-life of approximately 30 minutes. It is eliminated primarily by the renal route. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid-d5 Hydrochloride; Cytostasan-d5; Ribomustin-d5; Treanda-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bendamustine Deschloro Dimer Impurity | Bendamustine Deschloro Dimer Impurity is an impurity of Bendamustine. Synonyms: 4-[5-((2-((4-(5-(Bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanic Acid. Grades: > 95%. CAS No. 1391052-61-1. Molecular formula: C32H44N6O7. Mole weight: 624.74. | |
| Bendamustine Desmethyl Impurity | Bendamustine Desmethyl Impurity is an impurity of Bendamustine, an anticancer drug used to treat chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Synonyms: Bendamustine Desmethyl Impurity; Desmethyl Bendamustine Hydrochloride; 4-[6-[Bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]butanoic acid; hydrochloride; FT-0696961. Grades: > 95%. CAS No. 31349-38-9. Molecular formula: C15H19Cl2N3O2. Mole weight: 344.24. | |
| Bendamustine Dihydroxy Impurity | Bendamustine Dihydroxy Impurity is an impurity of Bendamustine. Synonyms: 5-[Bis(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid; Dihydroxy Bendamustine. Grades: > 95%. CAS No. 109882-30-6. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
| Bendamustine Dimer 2-Allyl Ester | Bendamustine Dimer 2-Allyl Ester is an dimer impurity of Bendamustine (B132500), an anticancer drug. Group: Biochemicals. Alternative Names: 4- (5- ( (2- ( (4- (5- (bis (2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl) (2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate Allyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bendamustine Dimer Impurity | Bendamustine Dimer Impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, 2-[[2-(3-carboxypropyl)-1-methyl-1H-benzimidazol-5-yl](2-chloroethyl)amino]ethyl ester, Bendamustine dimer, Bendamustine chloro dimer, Bendamustine Rel. Comp. H (USP), 4-[5-[2-[4-[5-[Bis(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butanoyloxy]ethyl-(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butanoic acid, 4-[5-({2-[(4-{5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoyl)oxy]ethyl}(2-chloroethyl)amino)-1-methyl-1H-benzimidazol-2-yl]butanoic acid. CAS No. 1228551-91-4. IUPAC Name: 4-[5-[2-[4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoyloxy]ethyl-(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid. Molecular formula: C32H41Cl3N6O4. Mole weight: 680.06. Catalog: APS1228551914. SMILES: Cn1c(CCCC(=O)O)nc2cc(ccc12)N(CCCl)CCOC(=O)CCCc3nc4cc(ccc4n3C)N(CCCl)CCCl. Format: Neat. |  |
| Bendamustine D-Mannitol Ester | Bendamustine D-Mannitol Ester. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1869075-89-7. Pack Sizes: 5MG. IUPAC Name: [(2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl] 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoate. Molecular formula: C22H33Cl2N3O7. Mole weight: 522.42. Catalog: APS1869075897. SMILES: Cn1c(CCCC(=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)nc2cc(ccc12)N(CCCl)CCCl. Format: Neat. Shipping: Room Temperature. | |
| Bendamustine Ether Impurity | Bendamustine Ether Impurity is an dimer impurity of Bendamustine. Synonyms: 4-(1-Methyl-5-morpholino-1H-benzo[d]imidazol-2-yl)butanoic Acid; 1-Methyl-5-(4-morpholinyl)-1H-benzimidazole-2-butanoic Acid. Grades: > 95%. CAS No. 1228552-02-0. Molecular formula: C16H21N3O3. Mole weight: 303.36. | |
| Bendamustine HCl USP | Cytostasan. Grades: USP. CAS No. 3543-75-7. Product ID: 1-01532. Molecular formula: C16H21Cl2N3O2.HCl. Mole weight: 394.73. Purity: MFCD00146679. |  |
| Bendamustine hydrochloride | 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride. alkylating agent recently approved by the FDA for treatment of Chronic Lymphocytic Leukemia. CAS No. 3543-75-7. Product ID: 2-08360. Molecular formula: C16H21Cl2N3O2.HCl. Mole weight: 394.72. Purity: 0.98. Properties: water soluble. | |
| Bendamustine hydrochloride | Bendamustine hydrochloride. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride; Cytostasan; Ribomustin. Grades: Highly Purified. CAS No. 3543-75-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H22Cl3N3O2. US Biological Life Sciences. | Worldwide |
| Bendamustine hydrochloride | Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDX-105. CAS No. 3543-75-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0077. | |
| Bendamustine hydrochloride | Bendamustine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bendamustine hydrochloride;BENDAMUSTIN HYDROCHLORIDE;CYTOSTASAN;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor;gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro;BENDAMUSTINE HCL. Appearance: powder. CAS No. 3543-75-7. Molecular formula: C16H22Cl3N3O2. Mole weight: 394.72. Purity: 98%+. IUPACName: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoicacid;hydrochloride. Canonical SMILES: CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl. Product ID: ACM3543757. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BendaMustine Hydrochloride | Bendamustine hydrochloride monotherapy or combination therapy has been designated by European and American clinical guidelines as a first - or second-line treatment option for a variety of hematological malignancies. CAS No. 3543-75-7. Product ID: PAP-0094. Molecular formula: C16H22Cl3N3O2. Product Keywords: Other Active Pharmaceutical Ingredients; BendaMustine Hydrochloride; PAP-0094; ; C16H22Cl3N3O2; 3543-75-7. Appearance: Powder. Color: off-white. EC Number: 631-540-0. Physical State: powder. Solubility: H2O: >30mg/mL. Storage: room temp. Applications: Treatment of Chronic Lymphocytic Leukemia (CLL). Melting Point: 149-151°C. |  |
| Bendamustine Hydrochloride (5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride, Cytostasan, Ribomustin, Treanda) | Used as an anticancer drug. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride; Cytostasan; Ribomustin; Treanda. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bendamustine hydrochloride hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Bendamustine Impurity 27 | Bendamustine Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-methyl-5-morpholino-1H-benzo[d]imidazol-2-yl)butanoic acid. CAS No. 1228552-02-0. Molecular formula: C16H21N3O3. Mole weight: 303.36. Catalog: APB1228552020. | |
| Bendamustine Impurity 7 | Bendamustine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1138238-08-0. Molecular formula: C16H21Cl2N3O3. Mole weight: 374.26. Catalog: APB1138238080. | |
| Bendamustine Impurity A | Bendamustine Impurity A is an impurity of Bendamustine, a drug for treating formidable non-Hodgkin lymphoma and the enduring chronic lymphocytic leukemia. Synonyms: 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid; Hydroxy BendaMustine. Grades: > 95%. CAS No. 109882-27-1. Molecular formula: C16H22ClN3O3. Mole weight: 339.83. | |
| Bendamustine Impurity B | Bendamustine Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1219709-87-1. Molecular formula: C32H43ClN6O6. Mole weight: 643.18. Catalog: APB1219709871. | |
| Bendamustine Impurity C | Bendamustine Impurity C is an impurity in commercial preparation of Bendamustine. Synonyms: Bendamustine Isopropyl Ester; 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Isopropyl Ester; Isopropyl 4-(5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl) butanoate. Grades: > 95%. CAS No. 1313020-25-5. Molecular formula: C19H27Cl2N3O2. Mole weight: 400.35. | |
| Bendamustine Impurity C | Bendamustine Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-((2-((4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid. CAS No. 1228551-91-4. Molecular formula: C32H41Cl3N6O4. Mole weight: 680.06. Catalog: APB1228551914. | |
| Bendamustine Impurity D | Bendamustine Impurity D is a degradation production of Bendamustine. Synonyms: 4-(6-(2-Chloroethyl)-3-methyl-3, 6, 7, 8-tetrahydroimidazo[4', 5':5, 6]benzo[1, 2-b][1, 4]thiazin-2-yl)butanoic Acid; 6-(2-Chloroethyl)-3,6,7,8-tetrahydro-3-methyl-Imidazo[4,5-h][1,4]benzothiazine-2-butanoic Acid; 4-(7,8-Dihydro-6-(2-Chloroethylamino)-3-methyl-1,4. Grades: > 95%. CAS No. 191939-34-1. Molecular formula: C16H20ClN3O2S. Mole weight: 353.87. | |
| Bendamustine intermediate | Bendamustine intermediate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester. Product Category: Heterocyclic Organic Compound. Appearance: Brown Solid. CAS No. 3543-73-5. Molecular formula: C14H19N3O2. Mole weight: 261.32. Product ID: ACM3543735. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bendamustine Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bendamustine Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bendamustine Related Compound H | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bendamustine Related Compound I | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bendamustine Related Impurity 1 | Cas No. 3543-74-6. | |
| Bendamustine Related Impurity 4 | Bendamustine Related Impurity 4 is an impurity of bendamustine, a chemotherapy drug used for the therapy of non-Hodgkin lymphoma and chronic lymphocytic leukemia. Synonyms: N1-Methylbenzene-1,2,4-triaMine; 1,2,4-BenzenetriaMine, N1-Methyl-. Grades: > 95%. CAS No. 60651-29-8. Molecular formula: C7H11N3. Mole weight: 137.19. | |
| Bendamustine Related Impurity 5 | Bendamustine Related Impurity 5 is an impurity of bendamustine, a novel pharmaceuticals designed to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma. Synonyms: 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Ethyl Ester. Grades: > 95%. CAS No. 898224-95-8. Molecular formula: C18H26ClN3O3. Mole weight: 367.88. | |
| 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride | 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride is a derivative of Bendamustine Hydrochloride (B132500), a compound used as a chemotherapy drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1793059-58-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C19H29Cl3N4O2, Molecular Weight: 451.82. US Biological Life Sciences. | Worldwide |
| 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride-D10 | 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride-D10 is a labelled analogue of 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride (D289355). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C19H19D10Cl3N4O2, Molecular Weight: 461.88. US Biological Life Sciences. | Worldwide |
| Deschloroethyl Bendamustine Hydrochloride | Deschloroethyl Bendamustine Hydrochloride. Group: Biochemicals. Alternative Names: 5-[(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid; 4-[5-(2-Chloroethylamino)-1-methylbenzimidazol-2-yl]butanoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C14H19Cl2N3O2, Molecular Weight: 332.23. US Biological Life Sciences. | Worldwide |
| Deschloroethyl Bendamustine Hydrochloride | Deschloroethyl Bendamustine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Bendamustine Related Compound D (USP) as HCl, 4-[5-[(2-Chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl]butanoic acid hydrochloride,1H-Benzimidazole-2-butanoic acid, 5-[(2-chloroethyl)amino]-1-methyl-, hydrochloride (1:1). CAS No. 1797881-48-1. IUPAC Name: 4-[5-(2-chloroethylamino)-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride. Molecular formula: C14H18ClN3O2.ClH. Mole weight: 332.23. Catalog: APS1797881481. SMILES: Cl.Cn1c(CCCC(=O)O)nc2cc(NCCCl)ccc12. Format: Neat. | |
| Desmethyl Bendamustine Hydrochloride | Desmethyl Bendamustine Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 31349-38-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Dihydroxy Bendamustine Sodium Salt | Dihydroxy Bendamustine Sodium Salt. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS007519. Format: Neat. Shipping: Room Temperature. | |
| Hydroxy bendamustine | Hydroxy bendamustine. Group: Biochemicals. Alternative Names: 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid. Grades: Highly Purified. CAS No. 109882-27-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H22ClN3O3. US Biological Life Sciences. | Worldwide |
| N-desmethyl bendamustine | N-desmethyl bendamustine is an impurity of bendamustine, a DNA alkylating agent used for the treatment of chronic lymphocytic leukemia (CLL). Synonyms: nor-Bendamustine; 4-[6-[bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]butanoic acid. Grades: ≥95%. CAS No. 41515-13-3. Molecular formula: C15H19Cl2N3O2. Mole weight: 344.24. | |
| 1,3-Bis[1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane | 1,3-Bis[1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane is an impurity of the drug Bendamustine (B132500). Bendamustine is used as an anticancer drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 914626-65-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H18N6O4, Molecular Weight: 394.38. US Biological Life Sciences. | Worldwide |
| 1-Methyl-5-amino-1H-benzimidazole-2-butanoic Acid Ethyl Ester-d3 | Labeled Bendamustine. Group: Biochemicals. Alternative Names: 5-Amino-1-methyl-. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 1-Methyl-5-nitro-1H-benzimidazole-2-butanoic Acid Ethyl Ester-d3 | Labeled Bendamustine. Group: Biochemicals. Alternative Names: 1-Methyl-5-nitro-2-benzimidazolebutyric Acid. Grades: Highly Purified. CAS No. unlabelled:3543-72-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 2,2'-(1,3-Propanediyl)bis[1-methyl-1H-benzimidazol-5-amine | 2,2'-(1,3-Propanediyl)bis[1-methyl-1H-benzimidazol-5-amine is an impurity of the drug Bendamustine (B132500). Bendamustine is used as an anticancer drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 847588-86-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H22N6, Molecular Weight: 333.42. US Biological Life Sciences. | Worldwide |
| 4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid | 4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid is an intermediate in the synthesis of Bendamustine (B132500), an anticancer drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid tert-Butyl Ester | 4- (5- (Bis (2- (benzyloxy) ethyl) amino) -1-methyl-1H-benzo[d]imidazol-2-yl) butanoic Acid tert-Butyl Ester is a protected intermediate in the synthesis of Bendamustine (B132500), an anticancer drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester | 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester. Group: Biochemicals. Alternative Names: Bendamustine Impurity. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C19H28ClN3O3, Molecular Weight: 381.9. US Biological Life Sciences. | Worldwide |
| 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Ethyl Ester | Bendamustine (B132500) impurity. Group: Biochemicals. Alternative Names: Bendamustine Impurity. Grades: Highly Purified. CAS No. 898224-95-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5- [ (2-tert-Butyldi methyl silyloxyethyl) (2-chloroethyl) amino] -1- methyl -1H-benzimidazole-2-butanoic Acid Ethyl Ester | Protected Bendamustine (B132500) impurity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Methyl Ester | 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Methyl Ester. Group: Biochemicals. Alternative Names: Bendamustine USP Impurity. Grades: Highly Purified. CAS No. 109882-25-9. Pack Sizes: 10mg. Molecular Formula: C17H23Cl2N3O2, Molecular Weight: 372.29. US Biological Life Sciences. | Worldwide |
| AZD3965 | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Synonyms: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. Grades: >98%. CAS No. 1448671-31-5. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. | |
| EDO-S101 | EDO-S101 is a pan HDAC inhibitor (IC50 = 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3, respectively). EDO-S101 is a first-in-class fusion molecule that combines DNA damaging effect of bendamustine with the pan-HDACi vorinostat. Synonyms: 7-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]-N-hydroxyheptanamide; EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride. CAS No. 1236199-60-2. Molecular formula: C19H28Cl2N4O2. Mole weight: 415.36. | |
| Glutaric Acid-2-methylamino-5-nitromonoanilide-d3 | Intermediate in the production of labeled Bendamustine. Group: Biochemicals. Alternative Names: 2'-(Methylamino)-5'-nitro-glutaranilic Acid-d3; 5-[[2-(Methylamino)-5-nitrophenyl]amino]-5-oxo-pentanoic Acid-d3. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Polatuzumab | Polatuzumab is a monoclonal antibody directed against CD79b, which is ubiquitously expressed on the surface of malignant B cells. Polatuzumab can be used in the synthesis of polatuzumab vedotin, an ADC indicated in combination with bendamustine and a rituximab product for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). CAS No. 2279068-37-8. | |
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