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5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride. alkylating agent recently approved by the FDA for treatment of Chronic Lymphocytic Leukemia. CAS No. 3543-75-7. Product ID: 2-08360. Molecular formula: C16H21Cl2N3O2.HCl. Mole weight: 394.72. Purity: 0.98. Properties: water soluble.
Bendamustine hydrochloride
Bendamustine hydrochloride. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride; Cytostasan; Ribomustin. Grades: Highly Purified. CAS No. 3543-75-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H22Cl3N3O2. US Biological Life Sciences.
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Bendamustine hydrochloride
Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDX-105. CAS No. 3543-75-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0077.
Bendamustine hydrochloride
Bendamustine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bendamustine hydrochloride;BENDAMUSTIN HYDROCHLORIDE;CYTOSTASAN;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor;gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro;BENDAMUSTINE HCL. Appearance: powder. CAS No. 3543-75-7. Molecular formula: C16H22Cl3N3O2. Mole weight: 394.72. Purity: 98%+. IUPACName: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoicacid;hydrochloride. Canonical SMILES: CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl. Product ID: ACM3543757. Alfa Chemistry ISO 9001:2015 Certified.
BendaMustine Hydrochloride
Bendamustine hydrochloride monotherapy or combination therapy has been designated by European and American clinical guidelines as a first - or second-line treatment option for a variety of hematological malignancies. CAS No. 3543-75-7. Product ID: PAP-0094. Molecular formula: C16H22Cl3N3O2. Product Keywords: Other Active Pharmaceutical Ingredients; BendaMustine Hydrochloride; PAP-0094; ; C16H22Cl3N3O2; 3543-75-7. Appearance: Powder. Color: off-white. EC Number: 631-540-0. Physical State: powder. Solubility: H2O: >30mg/mL. Storage: room temp. Applications: Treatment of Chronic Lymphocytic Leukemia (CLL). Melting Point: 149-151°C.
Used as an anticancer drug. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride; Cytostasan; Ribomustin; Treanda. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride is a derivative of Bendamustine Hydrochloride (B132500), a compound used as a chemotherapy drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1793059-58-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C19H29Cl3N4O2, Molecular Weight: 451.82. US Biological Life Sciences.
Betamustine acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450. >95% of the drug is bound to protein - primarily albumin. Only free bendamustine is active. Elimination is biphasic with a half-life of 6-10 minutes and a terminal half-life of approximately 30 minutes. It is eliminated primarily by the renal route. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid-d5 Hydrochloride; Cytostasan-d5; Ribomustin-d5; Treanda-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Deschloroethyl Bendamustine Hydrochloride
Deschloroethyl Bendamustine Hydrochloride. Group: Biochemicals. Alternative Names: 5-[(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid; 4-[5-(2-Chloroethylamino)-1-methylbenzimidazol-2-yl]butanoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C14H19Cl2N3O2, Molecular Weight: 332.23. US Biological Life Sciences.
Worldwide
Deschloroethyl Bendamustine Hydrochloride
Deschloroethyl Bendamustine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Bendamustine Related Compound D (USP) as HCl, 4-[5-[(2-Chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl]butanoic acid hydrochloride,1H-Benzimidazole-2-butanoic acid, 5-[(2-chloroethyl)amino]-1-methyl-, hydrochloride (1:1). CAS No. 1797881-48-1. IUPAC Name: 4-[5-(2-chloroethylamino)-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride. Molecular Formula: C14H18ClN3O2.ClH. Mole Weight: 332.23. Catalog: APS1797881481. SMILES: Cl.Cn1c(CCCC(=O)O)nc2cc(NCCCl)ccc12. Format: Neat.
Desmethyl Bendamustine Hydrochloride
Desmethyl Bendamustine Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 31349-38-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences.
Worldwide
Bendamustine
Bendamustine, a lbenzimidazol derivative, has been found to be an alkylating agent that acts through restraining DNA synthesis so that could be useful as an antineoplastic agent. Uses: Antineoplastic; bendamustine hydrochloride. Synonyms: 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;Bendamustine. Grades: 98%. CAS No. 16506-27-7. Molecular formula: C16H21Cl2N3O2. Mole weight: 358.26.
Bendamustine Desmethyl Impurity
Bendamustine Desmethyl Impurity is an impurity of Bendamustine, an anticancer drug used to treat chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Synonyms: Bendamustine Desmethyl Impurity; Desmethyl Bendamustine Hydrochloride; 4-[6-[Bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]butanoic acid; hydrochloride; FT-0696961. Grades: > 95%. CAS No. 31349-38-9. Molecular formula: C15H19Cl2N3O2. Mole weight: 344.24.
Bendamustine HCl
Bendamustine HCl. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride. CAS No. 3543-75-7. Molecular Formula: C16H22Cl3N3O2. Mole Weight: 394.72. Catalog: APB3543757.
Bendamustine Impurity 23
Bendamustine Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-((2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride. CAS No. 1797881-48-1. Molecular Formula: C14H19Cl2N3O2. Mole Weight: 332.23. Catalog: APB1797881481.
Bendamustine Impurity 31
Bendamustine Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 4-(5-((2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate hydrochloride. Molecular Formula: C16H23Cl2N3O2. Mole Weight: 360.28. Catalog: APB03176.
Bendamustine Impurity 33
Bendamustine Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate hydrochloride. Molecular Formula: C18H25Cl2N3O2·HCl. Mole Weight: 422.78. Catalog: APB03174.
Bendamustine Impurity B
Bendamustine Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-((2-chloroethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride. CAS No. 109882-27-1. Molecular Formula: C16H22ClN3O3·HCl. Mole Weight: 376.28. Catalog: APB109882271.
Bendamustine Impurity D
Bendamustine Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate hydrochloride. Molecular Formula: 18H25Cl2N3O2·HCl. Mole Weight: 422.78. Catalog: APB03213.
Bendamustine Related Impurity 10
Bendamustine Related Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-((2-chloroethyl)(2-ethoxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride. Molecular Formula: C18H26ClN3O3·HCl. Mole Weight: 404.33. Catalog: APB03203.
Bendamustine Related Impurity 9
Bendamustine Related Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-(bis(2-chloroethyl)amino)-1H-benzo[d]imidazol-2-yl)-4-hydroxybutanoic acid hydrochloride. Molecular Formula: C15H20Cl3N3O3. Mole Weight: 396.7. Catalog: APB03205.
EDO-S101
EDO-S101 is a pan HDAC inhibitor (IC50 = 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3, respectively). EDO-S101 is a first-in-class fusion molecule that combines DNA damaging effect of bendamustine with the pan-HDACi vorinostat. Synonyms: 7-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]-N-hydroxyheptanamide; EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride. CAS No. 1236199-60-2. Molecular formula: C19H28Cl2N4O2. Mole weight: 415.36.
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