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| Product | Description | |
|---|---|---|
| Bendamustine hydrochloride | Bendamustine hydrochloride. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride; Cytostasan; Ribomustin. Grades: Highly Purified. CAS No. 3543-75-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H22Cl3N3O2. US Biological Life Sciences. |  Worldwide |
| Bendamustine hydrochloride | Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis; it may induce mitotic catastrophe; and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism. Synonyms: SDX-105 (Cytostasane) HCl; SDX 105 (Cytostasane) HCl; SDX105 (Cytostasane) HCl. Grade: >98%. CAS No. 3543-75-7. Molecular formula: C16H21Cl2N3O2.HCl. Mole weight: 394.72. |  |
| Bendamustine hydrochloride | Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDX-105. CAS No. 3543-75-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0077. |  |
| Bendamustine hydrochloride | Bendamustine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bendamustine hydrochloride;BENDAMUSTIN HYDROCHLORIDE;CYTOSTASAN;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor;gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro;BENDAMUSTINE HCL. Appearance: powder. CAS No. 3543-75-7. Molecular formula: C16H22Cl3N3O2. Mole weight: 394.72. Purity: 98%+. IUPACName: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoicacid;hydrochloride. Canonical SMILES: CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl. Product ID: ACM3543757. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BendaMustine Hydrochloride | Bendamustine hydrochloride monotherapy or combination therapy has been designated by European and American clinical guidelines as a first - or second-line treatment option for a variety of hematological malignancies. CAS No. 3543-75-7. Product ID: PAP-0094. Molecular formula: C16H22Cl3N3O2. Product Keywords: Other Active Pharmaceutical Ingredients; BendaMustine Hydrochloride; PAP-0094; ; C16H22Cl3N3O2; 3543-75-7. Appearance: Powder. Color: off-white. EC Number: 631-540-0. Physical State: powder. Solubility: H2O: >30mg/mL. Storage: room temp. Applications: Treatment of Chronic Lymphocytic Leukemia (CLL). Melting Point: 149-151°C. |  |
| Bendamustine Hydrochloride (5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride, Cytostasan, Ribomustin, Treanda) | Used as an anticancer drug. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride; Cytostasan; Ribomustin; Treanda. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bendamustine hydrochloride hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride | 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride is a derivative of Bendamustine Hydrochloride (B132500), a compound used as a chemotherapy drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1793059-58-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C19H29Cl3N4O2, Molecular Weight: 451.82. US Biological Life Sciences. | Worldwide |
| 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride-D10 | 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride-D10 is a labelled analogue of 2-Desbutylcarboxy-2-(N-hydroxyheptanamino) Bendamustine Hydrochloride (D289355). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C19H19D10Cl3N4O2, Molecular Weight: 461.88. US Biological Life Sciences. | Worldwide |
| Bendamustine-d5 (major) Hydrochloride (5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid-d5 Hydrochloride; Cytostasan-d5; Ribomustin-d5; Treanda-d5) | Betamustine acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450. >95% of the drug is bound to protein - primarily albumin. Only free bendamustine is active. Elimination is biphasic with a half-life of 6-10 minutes and a terminal half-life of approximately 30 minutes. It is eliminated primarily by the renal route. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid-d5 Hydrochloride; Cytostasan-d5; Ribomustin-d5; Treanda-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bendamustine Ether Hydrochloride Impurity | Bendamustine Ether Hydrochloride Impurity is an impurity of Bendamustine, that is an anticancer drug used to treat chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Synonyms: Bendamustine Related Compound B; 4-(1-Methyl-5-morpholino-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride. CAS No. 2173004-95-8. Molecular formula: C16H22ClN3O3. Mole weight: 339.82. | |
| Deschloroethyl Bendamustine Hydrochloride | Deschloroethyl Bendamustine Hydrochloride. Group: Biochemicals. Alternative Names: 5-[(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid; 4-[5-(2-Chloroethylamino)-1-methylbenzimidazol-2-yl]butanoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C14H19Cl2N3O2, Molecular Weight: 332.23. US Biological Life Sciences. | Worldwide |
| Deschloroethyl Bendamustine Hydrochloride | Deschloroethyl Bendamustine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Bendamustine Related Compound D (USP) as HCl, 4-[5-[(2-Chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl]butanoic acid hydrochloride,1H-Benzimidazole-2-butanoic acid, 5-[(2-chloroethyl)amino]-1-methyl-, hydrochloride (1:1). CAS No. 1797881-48-1. IUPAC Name: 4-[5-(2-chloroethylamino)-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride. Molecular formula: C14H18ClN3O2.ClH. Mole weight: 332.23. Catalog: APS1797881481. SMILES: Cl.Cn1c(CCCC(=O)O)nc2cc(NCCCl)ccc12. Format: Neat. | |
| Desmethyl Bendamustine Hydrochloride | Desmethyl Bendamustine Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 31349-38-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Bendamustine | Bendamustine, a lbenzimidazol derivative, has been found to be an alkylating agent that acts through restraining DNA synthesis so that could be useful as an antineoplastic agent. Uses: Antineoplastic; bendamustine hydrochloride. Synonyms: 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid; 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid; Bendamustine. Grade: 98%. CAS No. 16506-27-7. Molecular formula: C16H21Cl2N3O2. Mole weight: 358.26. | |
| Bendamustine Desmethyl Impurity | Bendamustine Desmethyl Impurity is an impurity of Bendamustine, an anticancer drug used to treat chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Synonyms: Bendamustine Desmethyl Impurity; Desmethyl Bendamustine Hydrochloride; 4-[6-[Bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]butanoic acid; hydrochloride; FT-0696961. Grade: > 95%. CAS No. 31349-38-9. Molecular formula: C15H19Cl2N3O2. Mole weight: 344.24. | |
| Bendamustine Ethyl Ester | An impurity of Bendamustine, a drug for the treatment of severe non-Hodgkin lymphoma and chronic lymphocytic leukemia. Synonyms: 5-[Bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester; 1H-Benzimidazole-2-butanoic acid, 5-(bis(2-chloroethyl)amino)-1-methyl-, ethyl ester; Ethyl 5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzimidazole-2-butanoate; Ethyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzimidazol-2-yl)butanoate; USP Bendamustine Related Compound I; Bendamustine related compound I; Bendamustine USP Related Compound I; Bendamustine Hydrochloride USP Related Compound I. Grade: ≥95%. CAS No. 87475-54-5. Molecular formula: C18H25Cl2N3O2. Mole weight: 386.32. | |
| EDO-S101 | EDO-S101 is a pan HDAC inhibitor (IC50 = 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3, respectively). EDO-S101 is a first-in-class fusion molecule that combines DNA damaging effect of bendamustine with the pan-HDACi vorinostat. Synonyms: 7-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]-N-hydroxyheptanamide; EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride. CAS No. 1236199-60-2. Molecular formula: C19H28Cl2N4O2. Mole weight: 415.36. | |
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