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3-[1-[(1R)-1,2-Dihydro-1-acenaphthylenyl]-4-piperidinyl]-2,3-dihydro-2-oxo-1H-benzimidazole-1-acetic Acid Ethyl Ester is an opioid receptor-like 1 (ORL1) receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 610323-29-0. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C28H29N3O3, Molecular Weight: 455.55. US Biological Life Sciences.
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(R)-Omeprazole
(R)-Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: Anti-ulcer agents; proton pump inhibitors. Synonyms: 5-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; (+)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-1-acetic Acid; (+)-Omeprazole; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole. Grades: >95%. CAS No. 119141-89-8. Molecular formula: C17H19N3O3S. Mole weight: 345.42.
1-(2-Acetoxyethyl)-2-methyl-1H-benzoimidazole-5-carboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2-ACETOXYETHYL)-2-METHYL-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID;1-(2-ACETOXY-ETHYL)-2-METHYL-1 H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 282091-90-1. Molecular formula: C13H14N2O4. Mole weight: 262.26. Product ID: ACM282091901. Alfa Chemistry ISO 9001:2015 Certified.
2-(Benzimidazolylthio) acetic acid
2-(Benzimidazolylthio) acetic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 3042-00-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C9H8N2O2S. US Biological Life Sciences.
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2- (Benzimidazolylthio) acetic acid hydrazide
2- (Benzimidazolylthio) acetic acid hydrazide. Group: Biochemicals. Grades: Highly Purified. CAS No. 30065-27-1. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C9H10N4OS. US Biological Life Sciences.
Worldwide
(2-Methyl-1h-benzimidazol-1-yl)acetic acid
(2-Methyl-1h-benzimidazol-1-yl)acetic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 40332-17-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H10N2O2, Molecular Weight: 190.2. US Biological Life Sciences.
(5-Methyl-1H-benzoimidazol-2-ylsulfanyl)acetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (5-METHYL-1H-BENZOIMIDAZOL-2-YLSULFANYL)-ACETIC ACID;CHEMBRDG-BB 4140363;ASINEX-REAG BAS 16289554;TIMTEC-BB SBB011493;((5-METHYL-1H-BENZIMIDAZOL-2-YL)THIO)ACETIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 27231-37-4. Molecular formula: C10H10N2O2S. Mole weight: 222.26. Product ID: ACM27231374. Alfa Chemistry ISO 9001:2015 Certified.
Acetic acid((1-(3-thietanyl)-1H-benzo[d]imidazol-2-yl)thio)-,potassium salt
Acetic acid((1-(3-thietanyl)-1H-benzo[d]imidazol-2-yl)thio)-,potassium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID3075467, LS-12864, 2-(1-(Thietan-3-yl)benzimidazolyl-2-thio)acetic acid potassium salt, Potassium ((1-(3-thietanyl)-1H-benzimidazol-2-yl)thio)acetate, Acetic acid, ((1-(3-thietanyl)-1H-benzimidazol-2-yl)thio)-, potassium salt, 182193-17-5. Product Category: Heterocyclic Organic Compound. CAS No. 182193-17-5. Molecular formula: C12H11KN2O2S2. Mole weight: 318.45624. Purity: 0.96. IUPACName: potassium 2-[1-(thietan-3-yl)benzimidazol-2-yl]sulfanylacetate. Canonical SMILES: C1C(CS1)N2C3=CC=CC=C3N=C2SCC(=O)[O-].[K+]. Product ID: ACM182193175. Alfa Chemistry ISO 9001:2015 Certified.
Limiglidole is used as a antihyperglycaemic drug candidate. It shows antiplatelet activity 2-fold exceeded activity of antiplatelet agent acetylsalicylic acid in the mouse model of systemic collagen-epinephrine thrombosis. It significantly decreased the relative and mean area of blood clots in the sections of mouse lungs. Uses: Limiglidole is used as a antihyperglycaemic drug candidate. Synonyms: 2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)-N,N-diethylethanamine. Grades: 98%. CAS No. 64644-54-8. Molecular formula: C15H22N4. Mole weight: 258.37.
PCI-27483
PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VIIa) with potential antineoplastic and antithrombotic activities. FVII, a serine protease, becomes activated (FVIIa) upon binding with TF forming the FVIIa/TF complex, which induces intracellular signaling pathways by activating protease activated receptor 2 (PAR-2). Upon subcutaneous administration, factor VIIa inhibitor PCI-27483 selectively inhibits factor FVIIa in the VIIa/TF complex, which may prevent PAR-2 activation and PAR2-mediated signal transduction pathways, thereby inhibiting tumor cell proliferation, angiogenesis, and metastasis of TF-overexpressing tumor cells. In addition, this agent inhibits both the extrinsic and intrinsic coagulation cascades, preventing blood clot formation. TF, a blood protein overexpressed on the cell surface of a variety of tumor cell types, may correlate with poor prognosis; PAR-2 (also known as thrombin receptor-like 1) is a G protein-coupled receptor (GPCR) and a protease-activated receptor. PCI-27483 is in a clinical trial for the treatment of advanced pancreatic cancer in combination with Gemcitabine. Synonyms: PCI27483; PCI 27483; (2S) -2-[[2-[3- (6-carbamimidoyl-1H-benzimidazol-2-yl) -4-hydroxy-5- (2-hydroxy-5-sulfamoylphenyl) phenyl]acetyl]amino]butanedioic acid. Grades: ≥98%. CAS No. 871266-63-6. Molecular formula: C26H24N6O9S. Mole weight: 596.6.
PF 05175157
PF-05175157 is a selective inhibitor of both acetyl-CoA carboxylase isoform ACC1 and isoform ACC2 dominant. IC50 values are 27 nM and 33 nM, respectively. It was originated by Pfizer. ACC inihibitors can inhibit de novo lipogenesis and increase β-oxidation of long-chain fatty acids. In Feb 2015, Phase-II for Type-2 diabetes mellitus in USA was discontinued. Uses: Type 2 diabetes mellitus. Synonyms: PF-05175157; PF05175157; 1,4-Dihydro-1'-[(2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4'-piperidin]-7(6H)-one. Grades: 98%. CAS No. 1301214-47-0. Molecular formula: C23H27N5O2. Mole weight: 405.50.
Tmcb
TMCB is a selective, ATP-competitive CK2 (casein kinase II) inhibitor with distinct Ki values of 83 nM and 21 nM for the two different catalytic CK2 subunits α and α', respectively. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBL1233807, SureCN1759230, ABP000318, [4,5,6,7-Tetrabromo-2-(Dimethylamino)-1h-Benzimidazol-1-Yl]acetic Acid, 905105-89-7, K66. Product Category: Inhibitors. CAS No. 905105-89-7. Molecular formula: C11H9Br4N3O2. Mole weight: C11H9Br4N3O2. Purity: >98 %. IUPACName: 2-[4,5,6,7-tetrabromo-2-(dimethylamino)benzimidazol-1-yl]acetic acid. Canonical SMILES: CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br. Product ID: ACM905105897. Alfa Chemistry ISO 9001:2015 Certified. Categories: TMC Bulldogs.
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