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A reagent used to synthesize Ziprasidione. Group: Biochemicals. Alternative Names: 3-(Piperazin-1-yl)benzoisothiazole; N- (3-Benzisothiazolyl) piperazine; 1-(1,2-Benzisothiazol-3-yl)piperazine. Grades: Highly Purified. CAS No. 87691-87-0. Pack Sizes: 1g. US Biological Life Sciences.
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3-(1-Piperazinyl)-1,2-benzisothiazole 1-Oxide
3-(1-Piperazinyl)-1,2-benzisothiazole 1-Oxide is an intermediate in synthesizing Ziprasidone Sulfoxide (), a metabolite of Ziprasidone (Z485000). Group: Biochemicals. Grades: Highly Purified. CAS No. 128396-56-5. Pack Sizes: 25mg, 50mg. Molecular Formula: C11H13N3OS. US Biological Life Sciences.
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3-(1-Piperazinyl)-1,2-benzisothiazole Hydrochloride (1:1). (Ziprasidone Related Compound A)
3-(1-Piperazinyl)-1,2-benzisothiazole Hydrochloride (1:1)(Ziprasidone Related Compound A). Group: Biochemicals. Alternative Names: 3-(1-Piperazinyl)-1,2-benzisothiazole Monohydrochloride; 3-Piperazin-1-yl-benzo[d]isothiazole Hydrochloride; 3-Piperazinyl-1,2-benzisothiazole Hydrochloride; 4-(1,2-Benzisothiazol-3-yl)piperazine Hydrochloride; (3-(Piperazin-1-yl)benzo[d]isothiazole Monohydrochloride. Grades: Highly Purified. CAS No. 87691-88-1. Pack Sizes: 2.5mg. Molecular Formula: C11H14ClN3S, Molecular Weight: 255.77. US Biological Life Sciences.
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3-(1-Piperazinyl-d8)-1,2-benzisothiazole
3-(1-Piperazinyl-d8)-1,2-benzisothiazole is the labeled analogue of 3-(1-Piperazinyl)-1,2-benzisothiazole (P480600), a reagent used to synthesize Ziprasidone(Z485000), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H5D8N3S, Molecular Weight: 227.36. US Biological Life Sciences.
Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 160384-37-2. Pack Sizes: 100mg. US Biological Life Sciences.
Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 160384-38-3. Pack Sizes: 25mg. US Biological Life Sciences.
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3-Chloro-1,2-benzisothiazole
3-Chloro-1,2-benzisothiazole. Group: Biochemicals. Grades: Highly Purified. CAS No. 7716-66-7. Pack Sizes: 10g. US Biological Life Sciences.
6-Chloro-1,2-benzisothiazol-3(2H)-one (FER 1443, Landromil, Ticlaton, Ticlatone, 3-Hydroxy-6-chloro-1,2-benzisothiazole). Group: Biochemicals. Alternative Names: FER 1443, Landromil, Ticlaton, Ticlatone, 3-Hydroxy-6-chloro-1,2-benzisothiazole. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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(1R) - (-) - (10-Camphorsulfonyl) oxaziridine
(1R) - (-) - (10-Camphorsulfonyl) oxaziridine. Group: Biochemicals. Alternative Names: (4aR,7S,8aR)-Tetrahydro-9,9-dimethyl-4H-4a,7-methano-1,2-oxazirino[3,2-i]-2,1-benzisothiazole 3,3-dioxide. Grades: Highly Purified. CAS No. 104372-31-8. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C10H15NO3S. US Biological Life Sciences.
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(1S) - (+) - (10-Camphorsulfonyl) oxaziridine
(1S) - (+) - (10-Camphorsulfonyl) oxaziridine. Group: Biochemicals. Alternative Names: (4aS,7R,8aS)-Tetrahydro-9,9-dimethyl-4H-4a,7-methanooxazirino[3,2-i][2,1]benzisothiazole 3,3-dioxide. Grades: Highly Purified. CAS No. 104322-63-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H15NO3S. US Biological Life Sciences.
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(1S)-(-)-(7,7-Dichloro-10-camphorsulfonyl)imine
A useful synthetic intermediate. used in the synthesis of (+) -[ (8, 8-Dichlorocamphoryl) sulfonyl]oxaziridine. Group: Biochemicals. Alternative Names: (3aS,6S)-7,7-Dichloro-4,5,6,7-tetrahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole 2,2-Dioxide. Grades: Highly Purified. CAS No. 127184-04-7. Pack Sizes: 250mg. US Biological Life Sciences.
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(1S)-Camphorsultam
Reagent used to make Camphorsultam conjugates. Group: Biochemicals. Alternative Names: (1S)-(-)-10,2-Camphorsultam; (2R)-Bornane-10,2-sultam; Hexahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole. Grades: Highly Purified. CAS No. 94594-90-8. Pack Sizes: 1g. US Biological Life Sciences.
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3-Piperazin-1-yl-benzo[d]isothiazole
3-Piperazin-1-yl-benzo[d]isothiazole. Group: Biochemicals. Alternative Names: 1-(1,2-Benzisothiazol-3-yl)piperazine; 3-(1-Piperazinyl)-1,2-benzisothiazole; 3-Piperazinobenzisothiaz ole. Grades: Highly Purified. CAS No. 144010-02-6. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Impurity in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Alternative Names: 3-[4-[2-(2-Chloro-5-hydroxy-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-Benzisothiazole. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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6-Chloro-1,2-benzisothiazol-3(2H)-one
6-Chloro-1,2-benzisothiazol-3(2H)-one. Group: Biochemicals. Alternative Names: FER 1443, landromil, ticlaton, ticlatone, 3-hydroxy-6-chloro-1,2-benzisothiazole. Grades: Highly Purified. CAS No. 70-10-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C7H4ClNOS. US Biological Life Sciences.
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6-Chloro-3- (piperazin-1-yl) benzol[d]isothiazole
6-Chloro-3- (piperazin-1-yl) benzol[d]isothiazole. Group: Biochemicals. Alternative Names: 6-Chloro-3-(1-piperazinyl)-1,2-benzisothiazole; 1-(6-Chloro-1,2-benzisothiazol-3-yl)piperazine. Grades: Highly Purified. CAS No. 131540-87-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C11H12ClN3S. US Biological Life Sciences.
(-) - (8, 8-Dichlorocamphorylsulfonyl) oxaziridine, a highly potent oxidizing agent, is widely implemented for the synthesis of diverse drug intermediates. It boasts a number of advantageous features, including its impressive efficacy in facilitating the asymmetric oxidation of sulfides while simultaneously serving as the go-to tool for the production of chiral oxaziridines. Notably, this versatile compound's exceptional performance characteristics underscore its value to the wider scientific community as a key contributor to the advancement of knowledge and scientific study. Synonyms: (4aR,7R,8aS)-8,8-Dichlorotetrahydro-9,9-dimethyl-4H-4a,7-methanooxazirino[3,2-i][2,1]benzisothiazole 3,3-Dioxide; [2S-(2α,4aα,7α,8aR*)]-8,8-Dichlorotetrahydro-9,9-dimethyl-4H-4a,7-methanooxazirino[3,2-i][2,1]benzisothiazole 3,3-Dioxide; (-)-3,3-Dichloro-2,N-epoxy-exo-10,2-bornanesultam; 4H-4a,7-Methanooxazirino[3,2-i][2,1]benzisothiazole, 8,8-dichlorotetrahydro-9,9-dimethyl-, 3,3-dioxide, (4aR,7R,8aS)-. Grades: 95%. CAS No. 139628-16-3. Molecular formula: C10H13Cl2NO3S. Mole weight: 298.19.
An impurity of Piroxicam which is a non-selective COX inhibitor with an IC50 of 6 mM. Synonyms: 3-Oxo-1,2-benzisothiazole-2(3H)-acetic Acid 1-Methylethyl Ester 1,1-Dioxide; 1-Methylethyl (1,1-Dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetate; Isopropyl 3-Oxo-1,2-benzisothiazole-2(3H)acetate 1,1-Dioxide. Grades: > 95%. CAS No. 76508-37-7. Molecular formula: C12H13NO5S. Mole weight: 283.31.
Saccharin N-(2-acetic acid isopropyl ester)(piroxicam impurity F). Group: Biochemicals. Alternative Names: 3-Oxo-1,2-benzisothiazole-2(3H)-acetic Acid 1-Methylethyl Ester 1,1-Dioxide. Grades: Highly Purified. CAS No. 76508-37-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H13NO5S. US Biological Life Sciences.
Worldwide
1,2-Benzisothiazol-3(2H)-one
1,2-Benzisothiazol-3(2H)-one. Synonyms: Benzisothiazolin-3-on (BIT);Benzo[d]isothiazol-3(2H)-one;1,2-Benzisothiazolin-3-One(MIT);2$l^{4}-thia-6-azatricyclo[5.4.0.0^{2,6}]undeca-1(7),8,10-trien-5-one;1,2-benzo-isothiazolin-3-ketone;Acticide BIT;Apizas AP-DS;Bestcide 200K. CAS No. 2634-33-5. Pack Sizes: 1 kg. Product ID: CDF4-0113. Molecular formula: C7H5NOS. Category: Food Preservatives. Product Keywords: Food Ingredients; Food Preservatives; 1,2-Benzisothiazol-3(2H)-one; CDF4-0113; 2634-33-5; C7H5NOS; 220-120-9; 2634-33-5. Purity: 0.99. Color: White to Light yellow to Light orange. EC Number: 220-120-9. Physical State: Neat. Solubility: Soluble in dichloromethane, dimethyl sulfoxide, methanol. Storage: Keep in dark place,Sealed in dry,Room Temperature. Boiling Point: 360°C (rough estimate). Melting Point: 154-158 °C(lit.). Density: 1.2170 (rough estimate).
1,2-Benzisothiazol-3(2H)-one
5g Pack Size. Group: Building Blocks, Organics. Formula: C7H5NOS. CAS No. 2634-33-5. Prepack ID 90027172-5g. Molecular Weight 151.19. See USA prepack pricing.
1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, ammonium salt
2-? [ [ (1R, ?2R) ?-?2-? [ [4-? (1, ?2-?Benzisothiazol-?3-?yl) ?-?1-?piperazinyl] ?methyl] ?cyclohexyl] ?methyl] ?-1H-?isoindole-?1, ?3 (2H) ?-?dione is an intermediate in synthesizing Lurasidone Opened Imide (L474935), an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1260025-92-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C27H30N4O2S. US Biological Life Sciences.
Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Alternative Names: [5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitrophenyl]-propanedioic Acid Dimethyl Ester. Grades: Highly Purified. CAS No. 160384-39-4. Pack Sizes: 10mg. US Biological Life Sciences.
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2-Bromoaniline-d4
2-Bromoaniline-d4 is the labeled analogue of 2-Bromoaniline (B679950), a reagent used in the synthesis of substituted 2-carboxanilides as herbicides and antibacterials. Also used in the synthesis of benzisothiazol-3-one derivatives as caspase-3 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1643564-99-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6H2D4BrN, Molecular Weight: 176.05. US Biological Life Sciences.
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(2-Bromoethyl)benzene
(2-Bromoethyl)benzene is used in the synthesis of sulforaphane derivatives used as potential antitumor agents. As well, used in the synthesis of 1,2-benzisothiazol-3-one derivatives as potent caspase-3-inhibitors. Group: Biochemicals. Alternative Names: (2-Bromoethyl)benzene; 1-Bromo-2-phenylethane; 1-Phenyl-2-bromoethane; 2-Bromo-1-phenylethane; 2-Phenethyl Bromide; 2-Phenyl-1-bromoethane; 2-Phenylbromoethane; 2-Phenylethyl Bromide; NSC 33926; Phenethyl Bromide; Phenylethyl Bromide; β-Bromoethylbenzene; β-Phenethyl Bromide; β-Phenylethyl Bromide. Grades: Highly Purified. CAS No. 103-63-9. Pack Sizes: 50g. US Biological Life Sciences.
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2-Butyl-1,2-benzisothiazolin-3-one
5g Pack Size. Group: Analytical Reagents, Building Blocks, Organics. Formula: C11H13NOS. CAS No. 4299-7-4. Prepack ID 90028452-5g. Molecular Weight C11H13NOS=207.29. See USA prepack pricing.
Circulating cooling water system swimming pool water sterilization. Group: Biocide and algicide. Alternative Names: Benzisothiazolinone (BIT) Biocide. CAS No. 2634-33-5. Molecular formula: C7H5NOS. Mole weight: 151.18. Purity: 0.98. Catalog: ACM2634335-1.
Benzisothiazolin-3-one (BIT)
Benzisothiazolin-3-one (BIT). SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
A cell-permeable iron chelating benzisothiazolone compound with microbicide and fungicide properties that acts as a potent, selective, and reversible inhibitor of Jumonji AT-Rich Interactive Domain 1 (JARID1) histone demethylases (IC50 = 3uM for JARID1B). Also blocks the activity of other related demethylases at higher concentration (IC50 = 6, 4.9, and 28uM for JARID1A, JARID1C, and JMJD2E, respectively). However, it does affect the activity of unrelated UTX and JMJD3 H3K27me3 demethylases. HeLa cells overexpressing full length JARID1B show a significant reduction in H3K4Me3 activity following PBIT treatment (~10uM). Blocks the proliferation of UACC-812 tumor cells expressing higher levels of JARDID1B, but does not significantly affect MCF7 or MCF10A cells expressing lower levels of JARDID1B. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??NOS, Primary Target: JARID1 Histone Demethylases. US Biological Life Sciences.
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Ipsapirone
Ipsapirone is a selective partial agonist of the serotonin (5-HT) receptor 5-HT1A. Its Ki value is 10 nM in hippocampal membranes. It reduces 5-HT release in rat ventral hippocampus in vivo. It also inhibits passive avoidance behavior and foot shock-induced aggression in rats. It has anxiolytic effects in vivo. It has been used to treat borderline personality disorder and depression. Uses: Anti-anxiety agents. Synonyms: TVX Q 7821; 1,1-Dioxo-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-1,2-benzothiazol-3-one; 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide. Grades: ≥99% by HPLC. CAS No. 95847-70-4. Molecular formula: C19H23N5O3S. Mole weight: 401.48.
LOC14
LOC14 is a protein disulfide isomerase modulator with Kd value of 62 nM. It can force protein disulfide isomerase to adopt an oxidized conformation and suppress its activity. Synonyms: LOC14; LOC-14; LOC 14. 2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one. Grades: ≥98% by HPLC. CAS No. 877963-94-5. Molecular formula: C16H19N3O2S. Mole weight: 317.41.
Lurasidone-d8 Hydrochloride
A labeled analog of the antipsychotic Lurasidone, used for treatment of schizophrenia. Group: Biochemicals. Alternative Names: (3aR, 4S, 7R, 7aS) -2- [ [ (1R, 2R) -2- [ [4- (1, 2-Benzisothiazol-3-yl) -1-piperazinyl] methyl] cyclohexyl] methyl] hexahydro-4, 7-methano-1H-isoindole-1, 3 (2H) -dione-d8 Hydrochloride; Latuda-d8; SM 13496-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Lurasidone Hydrochloride
An antipsychotic used for treatment of schizophrenia. Group: Biochemicals. Alternative Names: (3aR, 4S, 7R, 7aS) -2- [ [ (1R, 2R) -2- [ [4- (1, 2-Benzisothiazol-3-yl) -1-piperazinyl] methyl] cyclohexyl] methyl] hexahydro-4, 7-methano-1H-isoindole-1, 3 (2H) -dione Hydrochloride; Latuda, SM 13496. Grades: Highly Purified. CAS No. 367514-88-3. Pack Sizes: 5mg. US Biological Life Sciences.
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M62812
M62812 is a toll-like receptor 4 (TLR4) transduction inhibitor. It inhibits LPS-induced NF-κB activation in HEK293 cells with IC50 value of 2.4 μg/mL). It also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. It could prolong survival in a mouse septic shock model. It suppresses endothelial cell and leukocyte activation, preventing lethal septic shock in mice. Synonyms: 6-(2-Aminophenoxy)-1,2-benzisothiazol-3-amine dihydrochloride; 6-(2-Aminophenoxy)-1,2-benzisothiazol-3-amine Hydrochloride (1:2). Grades: ≥98% by HPLC. CAS No. 613263-00-6. Molecular formula: C13H13N3OSCl2. Mole weight: 330.23.
N-Bromosaccharin
N-Bromosaccharin. Group: Biochemicals. Alternative Names: 2-Bromo-1,2-benzisothiazol-3(2H)-one 1,1-Dioxide. Grades: Highly Purified. CAS No. 35812-01-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
N-Iodosaccharin
N-Iodosaccharin. Group: Biochemicals. Alternative Names: 2-Iodo-1,2-benzisothiazol-3(2H)-one 1,1-Dioxide. Grades: Highly Purified. CAS No. 86340-94-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Worldwide
PBIT
PBIT is a JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor with IC50 values of 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively. It can increase trimethylation of H3K4 in HeLa cells and block the proliferation of tumor cells expressing high levels of JARID1B. Synonyms: 2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one. Grades: ≥98% by HPLC. CAS No. 2514-30-9. Molecular formula: C14H11NOS. Mole weight: 241.31.
Sweeteners. Alternative Names: 1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, potassium salt (1:1). CAS No. 10332-51-1. Mole weight: 221.28. Purity: 95%+. IUPACName: Potassium;1,1-dioxo-1,2-benzothiazol-2-id-3-one. Canonical SMILES: C1=CC=C2C(=C1)C(=O)[N-]S2(=O)=O.[K+].
Saccharin
It is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing. Group: Biochemicals. Alternative Names: 1,2-Benzisothiazol-3(2H)-one. Grades: Highly Purified. CAS No. 81-07-2. Pack Sizes: 100mg. US Biological Life Sciences.
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Saccharin
Saccharin is an orally active and non-caloric artificial sweetener used in beverages, foods, table-top sweeteners and oral hygiene products such as toothpastes and mouthwashs. Saccharin has bacteriostatic and microbiome-modulating properties. Synonyms: 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide; 1,2-Dihydro-2-ketobenzisosulfonazole; Benzoic Sulfimide; o-Benzosulfimide; Benzosulfimide; Garantose; Glucid; Gluside; NSC 5349; Saccharimide; o-Sulfobenzimide. Grades: 95%. CAS No. 81-07-2. Molecular formula: C7H5NO3S. Mole weight: 183.18.
Saccharin
Saccharin occurs as odorless white crystals or a white crystalline powder. It has an intensely sweet taste, with a metallic or bitter aftertaste that at normal levels of use can be detected by approximately 25% of the population. The aftertaste can be masked by blending saccharin with other sweeteners. Synonyms: 1, 2-Benzisothiazolin-3-one 1, 1-dioxide; benzoic acid sulfimide; benzoic sulfimide; benzosulfimide; 1, 2-dihydro-2-ketobenzisosulfonazole; 2, 3-dihydro-3-xobenzisosulfonazole; E954; Garantose; gluside; Hermesetas; sacarina; saccarina; saccharin insoluble; saccharinum; o-sulfobenzimide; o-sulfobenzoic acid imide. CAS No. 81-07-2. Product ID: PE-0483. Molecular formula: C7H5NO3S. Mole weight: 183.18. Category: Sweetening agent. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Saccharin; Sweeteners Excipients; Sweetening agent; C7H5NO3S; 81-07-2; 81-07-2. UNII: C151H8M554. Chemical Name: 1, 2-Benzisothiazol-3(2H)-one 1, 1-dioxide. Grade: Pharmceutical Excipients. Administration route: Oral; Topical. Dosage Form: Oral solutions, syrups, tablets, and topical preparations. Stability and Storage Conditions: Saccharin is stable under the normal range of conditions employed in formulations. In the bulk form it shows no detectable decomposition and only when it is exposed to a high temperature (125°C) at a low pH (pH 2) for over 1 hour does significant decomposition occur. The decomposition pr
Saccharin-13C6
It is a labeled non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing. Group: Biochemicals. Alternative Names: 1,2-(Benzisothiazol-13C6)-3(2H)-one. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Labeled Saccharin. It is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing. Group: Biochemicals. Alternative Names: 1,2-Benzisothiazol-3(2H)-one-d4. Grades: Highly Purified. CAS No. 1189466-17-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Saccharin sodium
Saccharin sodium. CAS No. 128-44-9. Product ID: PE-0004. Molecular formula: C7H5NNaO3S. Mole weight: 206.17. Category: Corrective Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Corrective Excipients; Saccharin sodium; PE-0004; C7H5NNaO3S; 128-44-9; 128-44-9. Appearance: White crystals or a white, crystalline efflorescent powder. Purity: 0.99. EC Number: 204-886-1. Synonym(s): 1,2-Benzothiazol-3(2H)-one 1,1-dioxide sodium salt;Sodium 1,1-dioxo-1,2-benzothiazol-2-id-3-one;2-Sodio-1,2-benzisothiazol-3(2H)-one 1,1-dioxide. Solubility: H2O: 1 M at 20 °C, clear, colorless; sparingly soluble in ethanol. Storage: 0-6°C. Melting Point: >300°C. Density: 1.69[at 20°C].
Saccharin sodium salt dihydrate
Sweeteners. Alternative Names: 1,2-Benzisothiazol-3(2h)-one 1,1-dioxide hydrate. CAS No. 82385-42-0. Mole weight: 223.18. Purity: 95%+. IUPACName: Sodium;1,1-dioxo-1,2-benzothiazol-2-id-3-one;hydrate. Canonical SMILES: C1=CC=C2C(=C1)C(=O)[N-]S2(=O)=O. O. [Na+].
SSR 69071
SSR 69071 is a potent and high affinity human leukocyte elastase (HLE) inhibitor (IC50 = 3.9 nM) that displays species-selectivity (Ki = 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase, respectively). SSR 69071 has been shown to inhibit HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduce infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Synonyms: SSR 69071; SSR69071; SSR-69071; 2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)ethoxy]-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: ≥98% by HPLC. CAS No. 344930-95-6. Molecular formula: C27H32N4O7S. Mole weight: 556.63.
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