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2,3,4,5-Tetrahydro-7-Methoxy-4-Methyl-1,4-Benzothiazepine-[d3]. Uses: T is a labelled benzothiazepine derivative that binds the ryr1 channel and enhances the binding affinity of calstabin-1. by preventing the depletion of calstabin-1 from the ryr1 complex, s 107 slows muscle fatique and reduces muscle damage in exercised mi. Synonyms: S 107; 2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-1,4-benzothiazepine. Grade: 95% atom D. CAS No. 1167435-22-4. Molecular formula: C11H12D3NOS. Mole weight: 212.33.
2-Methyl-2,3,4,5-tetrahydro-1,5-benzothiazepine
2-Methyl-2,3,4,5-tetrahydro-1,5-benzothiazepine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZINC03888612, ZINC03888613, CID7063925, 19197-44-5. Product Category: Heterocyclic Organic Compound. CAS No. 19197-44-5. Molecular formula: C10H13NS. Mole weight: 179.282. Purity: 0.96. IUPACName: (2S)-2-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepine. Canonical SMILES: CC1CCNC2=CC=CC=C2S1. Density: 1.057g/cm³. Product ID: ACM19197445. Alfa Chemistry ISO 9001:2015 Certified.
Intermediate in the production of labeled Diltiazem metabolites. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV). Group: Biochemicals. Grades: Highly Purified. CAS No. 115992-91-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C17H18N2O3S, Molecular Weight: 330.4. US Biological Life Sciences.
(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one-d4 is the isotope labelled analog of (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one. (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H14D4N2O3S, Molecular Weight: 334.43. US Biological Life Sciences.
3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-methyl-1,5-benzothiazepin-4(5H)-one is an impurity of Diltiazem (D460620), a calcium channel blocker with vasodilating activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 2067323-40-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H19NO4S, Molecular Weight: 357.42. US Biological Life Sciences.
An antianginal, antihypertensive. Regulates Calcium release from intracellular stores in neutrophils. Group: Biochemicals. Alternative Names: CRD-401, (2S,3S)-(+)-cis-3-(Acetoxy)-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, HCl. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
Used as an antipsychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties. Group: Biochemicals. Alternative Names: Seroquel, ICI-204636, Dibenzothiazepinohonep . Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
1-(3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)-3-((3,4-dimethoxyphenethyl)amino)propan-1-one is a calcium channel blocker with antihypertensive effects and can be used to study cardiovascular diseases. Synonyms: 5-[3-[[2-(3,4-dimethoxyphenyl)-ethyl]-amino]-1-oxopropyl]-2,3,4,5-tetrahydro-1,5-benzothiazepine; KT-362. Grade: >98.0%. CAS No. 93392-97-3. Molecular formula: C22H28N2O3S. Mole weight: 400.53.
2- [ [2- (3, 4-Dimethoxyphenyl) ethyl] methylamino] ethanol is used as a reagent in the synthesis of 3-hydroxy-2-(4-methoxphenyl)-5-(2-methylaminoethyl)-2,3-dihydro-5H-1,5-benzothiazepin-4-one derivatives which act as platelet aggregation inhibitors. It is also used in the synthesis of phenylalkanamines as antiarrhythmics. Group: Biochemicals. Grades: Highly Purified. CAS No. 126407-23-6. Pack Sizes: 100mg, 500mg. Molecular Formula: C13H21NO3, Molecular Weight: 239.31. US Biological Life Sciences.
2-[2- (4-Dibenzo[b, f][1, 4]thiazepin-11-yl-1-piperazinyl) ethoxy]ethyl Ester 2-Chloro-acetic Acid is an intermediate used in the synthesis of DI(2-(4-(dibenzo[b, f][1, 4]thiazepin-11-yl)piperazin-1-yl))-2-propoxyethyl Propionate (D417110), which is an impurity of Quetiapine (Q510000), which is used as an anti-psychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties. Neuroprotective product. Group: Biochemicals. Grades: Highly Purified. CAS No. 1798840-32-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C23H26ClN3O3S, Molecular Weight: 459.99. US Biological Life Sciences.
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2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-
2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S 107. Product Category: Heterocyclic Organic Compound. CAS No. 1167435-22-4. Molecular formula: C11H12D3NOS. Mole weight: 212.33. Purity: 0.96. IUPACName: 7-methoxy-4-(trideuteriomethyl)-3,5-dihydro-2H-1,4-benzothiazepine. Canonical SMILES: CN1CCSC2=C(C1)C=C(C=C2)OC. Product ID: ACM1167435224. Alfa Chemistry ISO 9001:2015 Certified.
2,3'-Dichloroacetophenone
2,3'-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 β (GSK-3 β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 21886-56-6. Pack Sizes: 1g, 5g. Molecular Formula: C8H6Cl2O. US Biological Life Sciences.
2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethanol Fumarate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethanol Fumarate,Quetiapine Fumarate Imp. I (EP), Quetiapine Fumarate Imp. I (EP) as Fumarate, Quetiapine Imp. I (EP). Pack Sizes: 50MG. IUPAC Name: 2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethanol;(E)-but-2-enedioic acid. Molecular formula: C19H21N3OS.C4H4O4. Mole weight: 455.53. Catalog: APS004196. SMILES: OCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OC(=O)\C=C\C(=O)O. Format: Neat. Shipping: Room Temperature.
2-Amino-5-methoxythiophenol
2-Amino-5-methoxythiophenol is a chemical reagent used in the synthesis of antibacterial benzothiazepines. Group: Biochemicals. Grades: Highly Purified. CAS No. 6274-29-9. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H9NOS, Molecular Weight: 155.22. US Biological Life Sciences.
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2-Methylallylamine
2-Methylallylamine is an intermediate used in the synthesis of urea-containing FK506 binding protein inhibitors. It is also used to prepare benzothiazepine dioxides with HIV-1 protease inhibitory activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 2878-14-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C4H9N, Molecular Weight: 71.12. US Biological Life Sciences.
Worldwide
(2R-trans)-Diltiazem hydrochloride
(2R-trans)-Diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2R-trans)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride; (+)-trans-Diltiazem hydrochloride. Grades: Highly Purified. CAS No. 103532-27-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H27ClN2O4S. US Biological Life Sciences.
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(2S-trans)-Diltiazem hydrochloride
(2S-trans)-Diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2S-trans)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride; (-)-trans-Diltiazem hydrochloride. Grades: Highly Purified. CAS No. 103532-26-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H27ClN2O4S. US Biological Life Sciences.
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3-(2-Thienyl)acrylic Acid
3-(2-Thienyl)acrylic Acid is used as a phenylalanine derivative which shows improved intestinal absorption of insulin in mice. In addition it has been used in the synthesis of novel benzothiazepinones as glycogen synthase kinase-3 β inhibitors. Group: Biochemicals. Alternative Names: 3-(2-Thienyl)-2-propenoic Acid; 2-Thiopheneacrylic Acid; 2-Thienylacrylic Acid; 3-(2-Thienyl)propenoic Acid; 3-(Thien-2-yl)acrylic Acid; 3-(Thiophene-2-yl)acrylic Acid; 3-Thiophen-2-ylacrylic Acid; NSC 4247. Grades: Highly Purified. CAS No. 1124-65-8. Pack Sizes: 10g. US Biological Life Sciences.
Intermediate in the preparation of Diltiazem metabolites. Group: Biochemicals. Alternative Names: (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-acetyloxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-acetyloxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: Highly Purified. CAS No. 85365-35-1. Pack Sizes: 25mg. US Biological Life Sciences.
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7-Hydroxy Quetiapine-d8
A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic. Group: Biochemicals. Alternative Names: 11-[4-[2-(2-Hydroxyethoxy)ethyl]-1-piperazinyl-d8]-dibenzo[b, f][1, 4]thiazepin-7-ol; ICI214227-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Aladorian
Aladorianis is a ryanodine receptor calcium release channel modulator. It is an antiarrhythmic agent. Clinical development for Chronic heart failure and Ventricular tachycardia was discontinued. Uses: Chronic heart failure; ventricular tachycardia. Synonyms: 2,3-Dihydro-7-methoxy-α-oxo-1,4-benzothiazepine-4(5H)-acetic Acid; ARM036; ARM-036; ARM 036; S36; S44121-1; Aladorian; Aladorian; S 36; S 44121-1. Grade: 98%. CAS No. 865433-00-7. Molecular formula: C12H13NO4S. Mole weight: 267.30.
BTM-1086
BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent. Synonyms: BTM1086; cis-2,3-dihydro-3-[(4-methylpiperazinyl)methyl]-2-phenyl-1,5-benzothiazepin-4(5H)-one. CAS No. 72293-17-5. Molecular formula: C21H25N3OS. Mole weight: 367.51.
CGP 37157
CGP 37157 is a a selective sodium-calcium exchanger inhibitor with IC50 value of 0.36 μM in isolated mitochondria. It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 can be used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. Synonyms: Cgp 37157; Cgp-37157; Cgp37157. 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one. Grade: 98%. CAS No. 75450-34-9. Molecular formula: C15H11Cl2NOS. Mole weight: 289.78.
CGP-37157 - CAS 75450-34-9
A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na+/Ca2+ exchanger (IC?? = 360 nM). Group: Fluorescence/luminescence spectroscopy.
Chlorosulfonic Acid
Chlorosulfuric Acid is used in the preparation of benzothiazepinyl phosphonate bile acid transporter inhibitor. Also used in the preparation ofsulfated guar gum for potential use as an antioxidant. Group: Biochemicals. Grades: Highly Purified. CAS No. 7790-94-5. Pack Sizes: 25g, 50g. Molecular Formula: ClHO3S. US Biological Life Sciences.
Deacetyl-O-demethyl Diltiazem Hydrochloride is a metabolite of Diltiazem Hydrochloride. Diltiazem is a calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a potent vasodilator. Uses: Diltiazem (d460620) metabolite. Synonyms: (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; Deacetyl-O-demethyl-d-diltiazem Hydrochloride; Deacetyl-O-demethyldiltiazem Hydrochloride. CAS No. 96252-32-3. Molecular formula: C19H23ClN2O3S. Mole weight: 394.92.
Deacetyl-O-demethyl Diltiazem Hydrochloride
Diltiazem metabolite. Group: Biochemicals. Alternative Names: (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; Deacetyl-O-demethyl-d-diltiazem Hydrochloride; Deacetyl-O-demethyldiltiazem Hydrochloride. Grades: Highly Purified. CAS No. 96252-32-3. Pack Sizes: 50mg. US Biological Life Sciences.
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Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem
A key intermediate for Diltiazem synthesis. Group: Biochemicals. Alternative Names: (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: Highly Purified. CAS No. 42399-49-5. Pack Sizes: 100mg. US Biological Life Sciences.
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Des[5-(2-dimethylamino)ethyl] Diltiazem
Diltiazem. Group: Biochemicals. Alternative Names: (2S,3S)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-. Grades: Highly Purified. CAS No. 87447-47-0. Pack Sizes: 25mg. US Biological Life Sciences.
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Desacetyl Diltiazem
A metabolite of Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis)-5-[(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Deacetyl-d-diltiazem; Deacetyldiltiazem. Grades: Highly Purified. CAS No. 42399-40-6. Pack Sizes: 10mg. US Biological Life Sciences.
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Desacetyl Diltiazem
Desacetyl Diltiazem. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Desacetyldiltiazem,(2S,3S)-5-[2-(Dimethylamino)-ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one, Diltiazem Hydrochloride Imp. F (EP). CAS No. 42399-40-6. IUPAC Name: (2S,3S)-5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one. Molecular formula: C20H24N2O3S. Mole weight: 372.48. Catalog: APS42399406. SMILES: COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2O. Format: Neat.
Desacetyl Diltiazem-d3
A labeled metabolite of Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis)-5-[(Dimethylamino-d3)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Deacetyl-d-diltiazem-d3; Deacetyldiltiazem-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Desacetyl Diltiazem-[d4]
Desacetyl Diltiazem-[d4] is the labelled analogue of Desacetyl Diltiazem, which is a metabolite of Diltiazem. Diltiazem is a nondihydropyridine calcium channel blocker which can be used in the treatment of hypertension. Synonyms: Desacetyl Diltiazem D4; (2S-cis)-5-[2-(Dimethylamino)ethyl-1,1,2,2-d4]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grade: 95% by HPLC; 98% atom D. CAS No. 112259-40-2. Molecular formula: C20H20D4N2O3S. Mole weight: 376.51.
Desacetyl Diltiazem-[d4] hydrochloride
Desacetyl Diltiazem-[d4] hydrochloride, is the labelled analogue of Desacetyl Diltiazem, which is a metabolite of Diltiazem. Diltiazem is a calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. Synonyms: (2S,3S)-5-[2-(Dimethylamino)ethyl-d4]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride; (2S-cis)-5-[2-(Dimethylamino)ethyl-d4]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride; Deacetyldiltiazem-d4 Hydrochloride. Grade: 98% (CP); 98% atom D. Molecular formula: C20H21D4ClN2O3S. Mole weight: 412.97.
Desacetyl Diltiazem-d6
A metabolite of labeled Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis)-5-[(Dimethylamino-d6)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Deacetyl-d-diltiazem-d6; Deacetyldiltiazem-d6. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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Desacetyl diltiazem HCl
Desacetyl Diltiazem Hydrochloride is a metabolite of Diltiazem Hydrochloride, a calcium channel blocher with vasodilating activity. Synonyms: (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride; (2S-cis)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride. Grade: > 95%. CAS No. 75472-91-2. Molecular formula: C20H24N2O3S·HCl. Mole weight: 408.94.
Diltiazem
Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Uses: A nondihydropyridines (non-dhp) calcium channel blocker. Synonyms: Cardizem; D-cis-Diltiazem; [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Grade: ≥95%. CAS No. 42399-41-7. Molecular formula: C22H26N2O4S. Mole weight: 414.52.
Diltiazem-[acetoxy-d3] Hydrochloride
Diltiazem-[acetoxy-d3] Hydrochloride is the labelled salt of Diltiazem, which is a calcium channel blocker medication used to treat high blood pressure, angina and certain heart arrhythmias. Synonyms: Diltiazem-d3 HCl; (+)-cis-Diltiazem-d3 HCl (acetoxy-d3); (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one-d3 Hydrochloride; Adizem-d3; Altiazem-d3; Dilzem-d3; Masdil-d3; Zilden-d3. Grade: 99% by HPLC; 99% atom D. CAS No. 1217860-13-3. Molecular formula: C22H24D3ClN2O4S. Mole weight: 454.00.
Diltiazem-[d3] Hydrochloride
Diltiazem-[d3] Hydrochloride is the labelled salt of Diltiazem, which is a calcium channel blocker medication used to treat high blood pressure, angina and certain heart arrhythmias. Synonyms: Diltiazem-d3 Hydrochloride; (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino-d3)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; Adizem-d3; Altiazem-d3; Dilzem-d3; Masdil-d3; Zilden-d3. Grade: 98%; ≥99% atom D. CAS No. 1217623-80-7. Molecular formula: C22H24D3ClN2O4S. Mole weight: 454.00.
Diltiazem-[d4] Hydrochloride
Diltiazem-[d4] Hydrochloride is a deuterium labelled form of Diltiazem. Diltiazem is a calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. Synonyms: (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino-d4)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; Diltiazem d4 HCl. Grade: 98% by CP; 98% atom D. CAS No. 1217769-52-2. Molecular formula: C22H23D4ClN2O4S. Mole weight: 455.00.
Diltiazem-d4 Hydrochloride
Labeled Diltiazem. A calcium channel blocker with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV). Group: Biochemicals. Alternative Names: (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino-d4)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; CRD-401-d4; Adizem-d4; Altiazem-d4; Dilzem-d4; Masdil-d4; Zilden-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Diltiazem-d6
Labelled Diltiazem (D460620). A calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV). Group: Biochemicals. Alternative Names: (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino-d6)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; CRD-401-d6; Adizem-d6; Altiazem-d6; Dilzem-d6; Masdil-d6; Zilden-d6. Grades: Highly Purified. CAS No. 1242184-41-3. Pack Sizes: 1mg. US Biological Life Sciences.
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Diltiazem DTZ-I Impurity
Diltiazem DTZ-I Impurity is an impurity of Diltiazem Hydrochloride. Diltiazem is a calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a potent vasodilator. Synonyms: N-Destrimethylamine Diltiazem; Des[5-(2-dimethylamino)ethyl] N-Methyl Diltiazem; 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-5-methyl-, acetate (ester), cis rel. CAS No. 30842-48-9. Molecular formula: C19H19NO4S. Mole weight: 357.42.
Diltiazem EP Impurity D
An impurity of Diltiazem, a calcium channel blocker used primarily to treat hypertension, angina pectoris, and certain types of heart rhythm disorders. Synonyms: N-Desmethyl Diltiazem; (2S,3S)-2-(4-Methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate; Diltiazem hydrochloride EP Impurity D; N-Monodemethyldiltiazem; (2S,3S)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one; 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-, (2S-cis)-; N-Demethyldiltiazem; N-Desmethyldiltiazem; N-Monodesmethyldiltiazem. Grade: ≥95%. CAS No. 86408-45-9. Molecular formula: C21H24N2O4S. Mole weight: 400.49.
Diltiazem HCl
Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. Synonyms: RG 83606 HCl; RG-83606 HCl; RG83606 HCl; Diltiazem hydrochloride; (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride. Grade: 98%. CAS No. 33286-22-5. Molecular formula: C22H27ClN2O4S. Mole weight: 450.98.
Diltiazem hydrochloride
Diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride; CRD-401; Adizem. Grades: Highly Purified. CAS No. 33286-22-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C22H27ClN2O4S. US Biological Life Sciences.
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Diltiazem, Hydrochloride - CAS 33286-22-5
Synthetic benzothiazepine that acts as an L-type Ca2+ channel antagonist. Group: Fluorescence/luminescence spectroscopy.
Diltiazem is a calcium channel antagonist. It can relax the smooth muscles in the walls of arteries, allow blood to flow more easily, and lower blood pressure. Meanwhile, it can lower blood pressure through acting on the heart itself to reduce the rate, strength, and conduction speed of each beat. Diltiazem can be used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. Uses: Hypertension, angina pectoris, and some types of arrhythmia. Synonyms: MK-793; MK 793; MK793; Tiamate; UNII-14Y6444DRP.; (+)-(2S,3S)-5-(2-(Dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester),(S)-malate (1:1); 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(di-methylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-(2S-cis)-, (S)-hydoxybutanedioate (1:1). Grade: 98%. CAS No. 144604-00-2. Molecular formula: C26H32N2O9S. Mole weight: 548.61.
Diltiazem N-Oxide
A metabolite of Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis) -3- (Acetyloxy) -5-[2- (dimethyloxidoamino) ethyl]-2, 3-dihydro-2- (4-methoxyphenyl) -1, 5-benzothiazepin-4 (5H) -one; 1,5-Benzothiazepin-4(5H)-one, (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one N-Oxide. Grades: Highly Purified. CAS No. 142843-04-7. Pack Sizes: 10mg. US Biological Life Sciences.
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Diltiazem N-Oxide
Diltiazem N-Oxide is a metabolite of Diltiazem Hydrochloride. Diltiazem is a calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a potent vasodilator. Uses: A metabolite of diltiazem (d460620). Synonyms: (2S-cis)-3-(Acetyloxy)-5-[2-(dimethyloxidoamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; 1,5-Benzothiazepin-4(5H)-one, (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one N-Oxide. CAS No. 142843-04-7. Molecular formula: C22H26N2O5S. Mole weight: 430.52.
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