benzothiazepin Suppliers USA

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Product
2,?3,?4,?5-?Tetrahydro-?4-?oxo-?1,?1-?dioxide-1,?5-?benzothiazepine-?3-?acetic acid 2,?3,?4,?5-?Tetrahydro-?4-?oxo-?1,?1-?dioxide-1,?5-?benzothiazepine-?3-?acetic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1171774-48-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C11H11NO5S, Molecular Weight: 269.27. US Biological Life Sciences. USBiological 10
Worldwide
2-Methyl-2,3,4,5-tetrahydro-1,5-benzothiazepine 2-Methyl-2,3,4,5-tetrahydro-1,5-benzothiazepine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZINC03888612, ZINC03888613, CID7063925, 19197-44-5. Product Category: Heterocyclic Organic Compound. CAS No. 19197-44-5. Molecular formula: C10H13NS. Mole weight: 179.282. Purity: 0.96. IUPACName: (2S)-2-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepine. Canonical SMILES: CC1CCNC2=CC=CC=C2S1. Density: 1.057g/cm³. Product ID: ACM19197445. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
(2S,3S)-[2-[3-(Acetoxy)-3,4-dihydro-2-(4-methoxyphenyl)-4-oxo-1,5-benzothiazepin-5(2H)-yl]ethyl]methyl-d3-carbamic Acid 1-Chloroethyl Ester Intermediate in the production of labeled Diltiazem metabolites. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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[(2S,3S)-2-(4-Methoxyphenyl)-5-[2-[methyl(propan-2-yl)amino]ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl]acetate [(2S,3S)-2-(4-Methoxyphenyl)-5-[2-[methyl(propan-2-yl)amino]ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl]acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Siratiazem, CID65989, (+)-(2S,3S)-2,3-Dihydro-3-hydroxy-5-(2-(isopropylmethylamino)ethyl)-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester), 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-(2-(methyl(1-methylethyl)amino)ethyl)-, cis-(+)-, 138778-28-6. Product Category: Heterocyclic Organic Compound. CAS No. 138778-28-6. Molecular formula: C24H30N2O4S. Mole weight: 442.571 g/mol. Purity: 0.96. IUPACName: [(2S,3S)-2-(4-methoxyphenyl)-5-[2-[methyl(propan-2-yl)amino]ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Canonical SMILES: CC(C)N(C)CCN1C2=CC=CC=C2SC(C(C1=O)OC(=O)C)C3=CC=C(C=C3)OC. Density: 1.22g/cm³. Product ID: ACM138778286. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV). Group: Biochemicals. Grades: Highly Purified. CAS No. 115992-91-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C17H18N2O3S, Molecular Weight: 330.4. US Biological Life Sciences. USBiological 10
Worldwide
(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one-d4 (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one-d4 is the isotope labelled analog of (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one. (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H14D4N2O3S, Molecular Weight: 334.43. US Biological Life Sciences. USBiological 10
Worldwide
3-Acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride 3-Acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: diltiazem, Cardizem, Diltiazem hydrochloride, Ambmdy02300214, SPECTRUM2300214, MolPort-003-666-774, HMS1922L18, EINECS 245-707-7, CID214464, NCGC00095200-01, NCGC00095200-02, LS-40521, 1,5-Benzothiazepin-4(5H)-one, 5-(2-(dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-, acetate (ester), hydrochloride, 23515-59-5, 3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride, 33232-39-2, 33286-22-5, cis -(+)-3-(Acetyloxy)-5-[2-(dimethyl-amino)ethyl]-2,3-dihydro-2-(4-methoxy-phenyl)-1,5-benzothiazepin -4(5H)-one. Product Category: Heterocyclic Organic Compound. CAS No. 23515-59-5. Molecular formula: C22H26N2O4S.HCl. Mole weight: 450.978780 [g/mol]. Purity: 0.96. IUPACName: [5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate hydrochloride. Product ID: ACM23515595. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-methyl-1,5-benzothiazepin-4(5H)-one 3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-methyl-1,5-benzothiazepin-4(5H)-one is an impurity of Diltiazem (D460620), a calcium channel blocker with vasodilating activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 2067323-40-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H19NO4S, Molecular Weight: 357.42. US Biological Life Sciences. USBiological 10
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[5-(2-Dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl]acetate [5-(2-Dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl]acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Product Category: Heterocyclic Organic Compound. CAS No. 34933-06-7. Molecular formula: C22H26N2O4S. Mole weight: 414.518 g/mol. Purity: 0.96. IUPACName: [5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Canonical SMILES: CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC. ECNumber: 252-295-2. Product ID: ACM34933067. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Dilacor XR. Alfa Chemistry. 3
7-Chloro-1,5-dihydro-5-(2-methylphenyl)-4,1-benzothiazepin-2(3H)-one 7-Chloro-1,5-dihydro-5-(2-methylphenyl)-4,1-benzothiazepin-2(3H)-one. Group: Biochemicals. Alternative Names: ITH-12505. Grades: Highly Purified. CAS No. 488829-66-9. Pack Sizes: 100mg. Molecular Formula: C16H14ClNOS, Molecular Weight: 303.81. US Biological Life Sciences. USBiological 3
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Diltiazem, Hydrochloride (CRD-401, (2S,3S)-(+)-cis-3-(Acetoxy)-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, HCl) An antianginal, antihypertensive. Regulates Calcium release from intracellular stores in neutrophils. Group: Biochemicals. Alternative Names: CRD-401, (2S,3S)-(+)-cis-3-(Acetoxy)-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, HCl. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences. USBiological 1
Worldwide
Quetiapine Hemifumarate (Seroquel, ICI-204636, Dibenzothiazepinohonep ) Used as an antipsychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties. Group: Biochemicals. Alternative Names: Seroquel, ICI-204636, Dibenzothiazepinohonep . Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. USBiological 1
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(R)-3-Boc-amino-5-(carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one (R)-3-Boc-amino-5-(carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences. USBiological 5
Worldwide
(R)-3-Fmoc-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one (R)-3-Fmoc-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences. USBiological 7
Worldwide
(R)-3-Fmoc-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 98+% (HPLC) (R)-3-Fmoc-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. USBiological 5
Worldwide
(R)-Boc-3-amino-5-carboxymethyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one ≥97% (HPLC) (R)-Boc-3-amino-5-carboxymethyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. USBiological 5
Worldwide
(S)-3-Boc-amino-5-(carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one (S)-3-Boc-amino-5-(carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one. Group: Biochemicals. Alternative Names: Boc-(S)-3-amino-2,3-dihydro-4-oxo-1,5-benzothiazepine-5(2H)-acetic acid. Grades: Highly Purified. CAS No. 250349-13-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. USBiological 6
Worldwide
(S)-3-Boc-amino-5-(carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 98+% (HPLC) (S)-3-Boc-amino-5-(carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. USBiological 5
Worldwide
11-hydroxy-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepine 5,5-dioxide An impurity of Tianeptine, which is a selective serotonin reuptake enhancer (SSRE) used for treating major depressive episodes. Synonyms: 6-Methyl-5,5-dioxo-11H-benzo[c][1,2]benzothiazepin-11-ol; 6,11-Dihydro-6-methyl-dibenzo[c,f][1,2]thiazepin-11-ol 5,5-Dioxide. CAS No. 26638-56-2. Molecular formula: C14H13NO3S. Mole weight: 275.322. BOC Sciences 8
2- [ [2- (3, 4-Dimethoxyphenyl) ethyl] methylamino] ethanol 2- [ [2- (3, 4-Dimethoxyphenyl) ethyl] methylamino] ethanol is used as a reagent in the synthesis of 3-hydroxy-2-(4-methoxphenyl)-5-(2-methylaminoethyl)-2,3-dihydro-5H-1,5-benzothiazepin-4-one derivatives which act as platelet aggregation inhibitors. It is also used in the synthesis of phenylalkanamines as antiarrhythmics. Group: Biochemicals. Grades: Highly Purified. CAS No. 126407-23-6. Pack Sizes: 100mg, 500mg. Molecular Formula: C13H21NO3, Molecular Weight: 239.31. US Biological Life Sciences. USBiological 9
Worldwide
2-[2- (4-Dibenzo[b, f][1, 4]thiazepin-11-yl-1-piperazinyl) ethoxy]ethyl Ester 2-Chloro-acetic Acid 2-[2- (4-Dibenzo[b, f][1, 4]thiazepin-11-yl-1-piperazinyl) ethoxy]ethyl Ester 2-Chloro-acetic Acid is an intermediate used in the synthesis of DI(2-(4-(dibenzo[b, f][1, 4]thiazepin-11-yl)piperazin-1-yl))-2-propoxyethyl Propionate (D417110), which is an impurity of Quetiapine (Q510000), which is used as an anti-psychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties. Neuroprotective product. Group: Biochemicals. Grades: Highly Purified. CAS No. 1798840-32-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C23H26ClN3O3S, Molecular Weight: 459.99. US Biological Life Sciences. USBiological 9
Worldwide
2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)- 2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S 107. Product Category: Heterocyclic Organic Compound. CAS No. 1167435-22-4. Molecular formula: C11H12D3NOS. Mole weight: 212.33. Purity: 0.96. IUPACName: 7-methoxy-4-(trideuteriomethyl)-3,5-dihydro-2H-1,4-benzothiazepine. Canonical SMILES: CN1CCSC2=C(C1)C=C(C=C2)OC. Product ID: ACM1167435224. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
2,3'-Dichloroacetophenone 2,3'-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 β (GSK-3 β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 21886-56-6. Pack Sizes: 1g, 5g. Molecular Formula: C8H6Cl2O. US Biological Life Sciences. USBiological 10
Worldwide
2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethanol Fumarate 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethanol Fumarate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethanol Fumarate,Quetiapine Fumarate Imp. I (EP), Quetiapine Fumarate Imp. I (EP) as Fumarate, Quetiapine Imp. I (EP). Pack Sizes: 50MG. IUPAC Name: 2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethanol;(E)-but-2-enedioic acid. Molecular Formula: C19H21N3OS.C4H4O4. Mole Weight: 455.53. Catalog: APS004196. SMILES: OCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24. OC(=O)\C=C\C(=O)O. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products
2-Amino-5-methoxythiophenol 2-Amino-5-methoxythiophenol is a chemical reagent used in the synthesis of antibacterial benzothiazepines. Group: Biochemicals. Grades: Highly Purified. CAS No. 6274-29-9. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H9NOS, Molecular Weight: 155.22. US Biological Life Sciences. USBiological 9
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2-Methylallylamine 2-Methylallylamine is an intermediate used in the synthesis of urea-containing FK506 binding protein inhibitors. It is also used to prepare benzothiazepine dioxides with HIV-1 protease inhibitory activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 2878-14-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C4H9N, Molecular Weight: 71.12. US Biological Life Sciences. USBiological 10
Worldwide
(2R-trans)-Diltiazem hydrochloride (2R-trans)-Diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2R-trans)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride; (+)-trans-Diltiazem hydrochloride. Grades: Highly Purified. CAS No. 103532-27-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H27ClN2O4S. US Biological Life Sciences. USBiological 7
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(2S-trans)-Diltiazem hydrochloride (2S-trans)-Diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2S-trans)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride; (-)-trans-Diltiazem hydrochloride. Grades: Highly Purified. CAS No. 103532-26-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H27ClN2O4S. US Biological Life Sciences. USBiological 7
Worldwide
3-(2-Thienyl)acrylic Acid 3-(2-Thienyl)acrylic Acid is used as a phenylalanine derivative which shows improved intestinal absorption of insulin in mice. In addition it has been used in the synthesis of novel benzothiazepinones as glycogen synthase kinase-3 β inhibitors. Group: Biochemicals. Alternative Names: 3-(2-Thienyl)-2-propenoic Acid; 2-Thiopheneacrylic Acid; 2-Thienylacrylic Acid; 3-(2-Thienyl)propenoic Acid; 3-(Thien-2-yl)acrylic Acid; 3-(Thiophene-2-yl)acrylic Acid; 3-Thiophen-2-ylacrylic Acid; NSC 4247. Grades: Highly Purified. CAS No. 1124-65-8. Pack Sizes: 10g. US Biological Life Sciences. USBiological 3
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3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine, 95% 3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine, 95%. Group: other glass and ceramic materials. CAS No. 26723-60-4. Product ID: 3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-ol. Molecular formula: 309.8g/mol. Mole weight: C14H12ClNO3S. CN1C2=CC=CC=C2C (C3=C (S1 (=O)=O)C=C (C=C3)Cl)O. InChI=1S / C14H12ClNO3S / c1-16-12-5-3-2-4-10 (12) 14 (17) 11-7-6-9 (15) 8-13 (11) 20 (16, 18) 19 / h2-8, 14, 17H, 1H3. KBRSJPHSCOAFDR-UHFFFAOYSA-N. Alfa Chemistry Materials 5
4’-O-Desmethyl 4’-O-Acetyl Diltiazem Intermediate in the preparation of Diltiazem metabolites. Group: Biochemicals. Alternative Names: (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-acetyloxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-acetyloxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: Highly Purified. CAS No. 85365-35-1. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
Worldwide
6-methyldibenzo[c,f][1,2]thiazepin-11(6H)-one 5,5-dioxide An impurity of Tianeptine, which is a selective serotonin reuptake enhancer (SSRE) used for treating major depressive episodes. Synonyms: Dibenzo[c,f][1,2]thiazepin-11(6H)-one, 6-methyl-, 5,5-dioxide; 10-methyl-9; SCHEMBL19194634; DTXSID901180125; 6-methyl-5,5-dioxobenzo[c][1,2]benzothiazepin-11-one; 10-methyl-9|E?-thia-10-azatricyclo[9.4.0.0?,?]pentadeca-1(11),3(8),4,6,12,14-hexaene-2,9,9-trione. CAS No. 26638-46-0. Molecular formula: C14H11NO3S. Mole weight: 273.31. BOC Sciences
7-Hydroxy Quetiapine-d8 A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic. Group: Biochemicals. Alternative Names: 11-[4-[2-(2-Hydroxyethoxy)ethyl]-1-piperazinyl-d8]-dibenzo[b, f][1, 4]thiazepin-7-ol; ICI214227-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
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Aladorian Aladorianis is a ryanodine receptor calcium release channel modulator. It is an antiarrhythmic agent. Clinical development for Chronic heart failure and Ventricular tachycardia was discontinued. Uses: Chronic heart failure; ventricular tachycardia. Synonyms: 2,3-Dihydro-7-methoxy-α-oxo-1,4-benzothiazepine-4(5H)-acetic Acid; ARM036; ARM-036; ARM 036; S36; S44121-1; Aladorian; Aladorian; S 36; S 44121-1. Grades: 98%. CAS No. 865433-00-7. Molecular formula: C12H13NO4S. Mole weight: 267.30. BOC Sciences
CGP 37157 CGP 37157 is a a selective sodium-calcium exchanger inhibitor with IC50 value of 0.36 μM in isolated mitochondria. It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 can be used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. Synonyms: Cgp 37157; Cgp-37157; Cgp37157. 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one. Grades: 98%. CAS No. 75450-34-9. Molecular formula: C15H11Cl2NOS. Mole weight: 289.78. BOC Sciences 9
Chlorosulfonic Acid Chlorosulfuric Acid is used in the preparation of benzothiazepinyl phosphonate bile acid transporter inhibitor. Also used in the preparation ofsulfated guar gum for potential use as an antioxidant. Group: Biochemicals. Grades: Highly Purified. CAS No. 7790-94-5. Pack Sizes: 25g, 50g. Molecular Formula: ClHO3S. US Biological Life Sciences. USBiological 5
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(+)-cis-Diltiazem Hydrochloride, ≥98% (+)-cis-Diltiazem Hydrochloride, ≥98%. Group: other glass and ceramic materials. CAS No. 33286-22-5. Product ID: [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate; hydrochloride. Molecular formula: 451g/mol. Mole weight: C22H27ClN2O4S. CC (=O)OC1C (SC2=CC=CC=C2N (C1=O)CCN (C)C)C3=CC=C (C=C3)OC. Cl. InChI=1S/C22H26N2O4S. ClH/c1-15 (25)28-20-21 (16-9-11-17 (27-4)12-10-16)29-19-8-6-5-7-18 (19)24 (22 (20)26)14-13-23 (2)3; /h5-12, 20-21H, 13-14H2, 1-4H3; 1H/t20-, 21+; /m1. /s1. HDRXZJPWHTXQRI-BHDTVMLSSA-N. Alfa Chemistry Materials 5
Deacetyl-O-demethyl Diltiazem Hydrochloride Diltiazem metabolite. Group: Biochemicals. Alternative Names: (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; Deacetyl-O-demethyl-d-diltiazem Hydrochloride; Deacetyl-O-demethyldiltiazem Hydrochloride. Grades: Highly Purified. CAS No. 96252-32-3. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 2
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Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem A key intermediate for Diltiazem synthesis. Group: Biochemicals. Alternative Names: (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: Highly Purified. CAS No. 42399-49-5. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
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Des[5-(2-dimethylamino)ethyl] Diltiazem Diltiazem. Group: Biochemicals. Alternative Names: (2S,3S)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-. Grades: Highly Purified. CAS No. 87447-47-0. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
Worldwide
Desacetyl Diltiazem A metabolite of Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis)-5-[(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Deacetyl-d-diltiazem; Deacetyldiltiazem. Grades: Highly Purified. CAS No. 42399-40-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
Desacetyl Diltiazem Desacetyl Diltiazem. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Desacetyldiltiazem,(2S,3S)-5-[2-(Dimethylamino)-ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one, Diltiazem Hydrochloride Imp. F (EP). CAS No. 42399-40-6. IUPAC Name: (2S,3S)-5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one. Molecular Formula: C20H24N2O3S. Mole Weight: 372.48. Catalog: APS42399406. SMILES: COc1ccc (cc1)[C@@H]2Sc3ccccc3N (CCN (C)C)C (=O)[C@@H]2O. Format: Neat. Alfa Chemistry Analytical Products
Desacetyl Diltiazem-d3 A labeled metabolite of Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis)-5-[(Dimethylamino-d3)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Deacetyl-d-diltiazem-d3; Deacetyldiltiazem-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Desacetyl Diltiazem-d6 A metabolite of labeled Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis)-5-[(Dimethylamino-d6)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Deacetyl-d-diltiazem-d6; Deacetyldiltiazem-d6. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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Desacetyl diltiazem HCl Desacetyl Diltiazem Hydrochloride is a metabolite of Diltiazem Hydrochloride, a calcium channel blocher with vasodilating activity. Synonyms: (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride; (2S-cis)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride. Grades: > 95%. CAS No. 75472-91-2. Molecular formula: C20H24N2O3S·HCl. Mole weight: 408.94. BOC Sciences 6
Diltiazem Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Uses: A nondihydropyridines (non-dhp) calcium channel blocker. Synonyms: Cardizem; D-cis-Diltiazem; [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Grades: ≥95%. CAS No. 42399-41-7. Molecular formula: C22H26N2O4S. Mole weight: 414.52. BOC Sciences 10
Diltiazem-d4 Hydrochloride Labeled Diltiazem. A calcium channel blocker with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV). Group: Biochemicals. Alternative Names: (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino-d4)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; CRD-401-d4; Adizem-d4; Altiazem-d4; Dilzem-d4; Masdil-d4; Zilden-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
Diltiazem-d6 Labelled Diltiazem (D460620). A calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV). Group: Biochemicals. Alternative Names: (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino-d6)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; CRD-401-d6; Adizem-d6; Altiazem-d6; Dilzem-d6; Masdil-d6; Zilden-d6. Grades: Highly Purified. CAS No. 1242184-41-3. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
Diltiazem HCl 1,5-Benzothiazepin-4(5H)one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,monohydrochloride,(+)-cis-. Anxiolytic, Muscle Relaxant. Grades: USP. CAS No. 33286-22-5. Product ID: 8-01405. Molecular formula: C22H26N2O4S.HCl. Mole weight: 450.99. CarboMer Inc
Diltiazem HCl Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. Synonyms: RG 83606 HCl; RG-83606 HCl; RG83606 HCl. Grades: >98%. CAS No. 33286-22-5. Molecular formula: C22H26N2O4S.HCl. Mole weight: 450.98. BOC Sciences 6
Diltiazem hydrochloride Diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride; CRD-401; Adizem. Grades: Highly Purified. CAS No. 33286-22-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C22H27ClN2O4S. US Biological Life Sciences. USBiological 7
Worldwide
Diltiazem Impurity B Diltiazem impurity. Synonyms: (2S,3S)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-Benzothiazepin-4(5H)-one. Grades: > 95%. CAS No. 87447-47-0. Molecular formula: C18H17NO4S. Mole weight: 343.4. BOC Sciences 6
Diltiazem Impurity D (N-Desmethyl diltiazem HCl) A metabolite of Diltiazem. Synonyms: (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one Monohydrochloride; N-Demethyldiltiazem. Grades: > 95%. CAS No. 130606-60-9. Molecular formula: C21H25ClN2O4S. Mole weight: 436.95. BOC Sciences 6
Diltiazem Impurity E A key intermediate for Diltiazem. Synonyms: (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: > 95%. CAS No. 42399-49-5. Molecular formula: C16H15NO3S. Mole weight: 301.36. BOC Sciences 6
Diltiazem Impurity H (N,N,O-Tridesmethyl Desacetyl Diltiazem) Diltiazem impurity. Synonyms: (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: > 95%. CAS No. 115992-91-1. Molecular formula: C17H18N2O3S. Mole weight: 330.4. BOC Sciences 6
Diltiazem Malate Diltiazem is a calcium channel antagonist. It can relax the smooth muscles in the walls of arteries, allow blood to flow more easily, and lower blood pressure. Meanwhile, it can lower blood pressure through acting on the heart itself to reduce the rate, strength, and conduction speed of each beat. Diltiazem can be used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. Uses: Hypertension, angina pectoris, and some types of arrhythmia. Synonyms: MK-793; MK 793; MK793; Tiamate; UNII-14Y6444DRP.;(+)-(2S,3S)-5-(2-(Dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester),(S)-malate (1:1);1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(di-methylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-(2S-cis)-, (S)-hydoxybutanedioate (1:1). Grades: 98%. CAS No. 144604-00-2. Molecular formula: C26H32N2O9S. Mole weight: 548.61. BOC Sciences 10
Diltiazem N-Oxide A metabolite of Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis) -3- (Acetyloxy) -5-[2- (dimethyloxidoamino) ethyl]-2, 3-dihydro-2- (4-methoxyphenyl) -1, 5-benzothiazepin-4 (5H) -one; 1,5-Benzothiazepin-4(5H)-one, (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one N-Oxide. Grades: Highly Purified. CAS No. 142843-04-7. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
Elobixibat Elobixibat is a potent and selective IBAT inhibitor under development for the treatment of chronic constipation and irritable bowel syndrome with constipation. Uses: Sodium-bile acid cotransporter-inhibitor. Synonyms: AZD-7806; AZD 7806; AZD7806; A 3309; A3309; A-3309; AJG-533; (2R)-N-[2-[[3,3-Dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycylglycine. Grades: ≥95%. CAS No. 439087-18-0. Molecular formula: C36H45N3O7S2. Mole weight: 695.89. BOC Sciences 9
ITH 12575 ITH 12575, a potent and selective inhibitor of mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor, reduced Ca(2+) influx through CALHM1 at low micromolar concentrations. It can be used to study the physiological roles of the mitochondrial sodium /calcium exchanger related to neurodegeneration. Synonyms: ITH-12575; ITH 12575; ITH12575; 7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one; ITH-12575; ITH12575. Grades: ≥98% by HPLC. CAS No. 1802013-08-6. Molecular formula: C18H18ClNOS. Mole weight: 331.86. BOC Sciences 10
JTV 519 fumarate The fumarate salt form of JTV 519, which has been found to be a Ryanodine receptor (RyR) inhibitor and also could be a useful intermediate. Synonyms: JTV 519 fumarate; JTV519 fumarate; JTV-519 fumarate; 1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone fumarate. Grades: ≥98% by HPLC. CAS No. 1883549-36-7. Molecular formula: C25H32N2O2.C4H4O4. Mole weight: 540.67. BOC Sciences 9
N-Desmethyl Diltiazem-d3 Hydrochloride A metabolite of Diltiazem , an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils. Group: Biochemicals. Alternative Names: (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino-d4)ethyl]-1,5-benzothiazepin-4(5H)-one-d3 Monohydrochloride; N-Demethyldiltiazem-d3;N-Monodesmethyldiltiazem-d3. Grades: Highly Purified. CAS No. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
N-Desmethyl Diltiazem-d4 Hydrochloride A metabolite of Diltiazem , an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils. Group: Biochemicals. Alternative Names: (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino-d4)ethyl]-1,5-benzothiazepin-4(5H)-one Monohydrochloride; N-Demethyldiltiazem-d4;N-Monodesmethyldiltiazem-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
N-Desmethyl diltiazem hydrochloride N-Desmethyl diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one monohydrochloride; N-Demethyldiltiazem; N-Monodes methyl diltiazem. Grades: Highly Purified. CAS No. 130606-60-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H25ClN2O4S. US Biological Life Sciences. USBiological 7
Worldwide
N-Desmethyldiltiazem hydrochloride N-Desmethyldiltiazem hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-DESMETHYLDILTIAZEM, HYDROCHLORIDE;N-DemethyldiltiazemN-Monodesmethyldiltiazem,HCl;?N-Monodesmethyldiltiazem;(2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one Monohydrochloride;N-Demethyldiltiaz. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 130606-60-9. Molecular formula: C21H24N2O4S.HCl. Mole weight: 436.95. Product ID: ACM130606609. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
N-Desmethyl Diltiazem Hydrochloride N-Desmethyl Diltiazem Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Diltiazem Hydrochloride Imp. D (EP), Diltiazem Hydrochloride Imp. D (EP) as Hydrochloride, (2S,3S)-2-(4-Methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl Acetate Hydrochloride, Diltiazem Imp. D (EP), N-Desmethyl-diltiazem Hydrochloride. CAS No. 130606-60-9. IUPAC Name: [(2S,3S)-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride. Molecular Formula: C21H24N2O4S.ClH. Mole Weight: 436.95. Catalog: APS130606609. SMILES: Cl. CNCCN1C (=O)[C@H] (OC (=O)C)[C@@H] (Sc2ccccc12)c3ccc (OC)cc3. Format: Neat. Alfa Chemistry Analytical Products
N,N-Didesmethyl Diltiazem Hydrochloride A metabolite of Diltiazem. Group: Biochemicals. Alternative Names: (2S-cis)-3-(Acetyloxy)-5-(2-aminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride; (2S,3S)-N,N-Didemethyldiltiazem Hydrochloride. Grades: Highly Purified. CAS No. 116050-35-2. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
N,N,O-Tridesmethyl diltiazem N,N,O-Tridesmethyl diltiazem. Group: Biochemicals. Alternative Names: (2S,3S)-3-(Acetyloxy)-5-(2-aminoethyl)-2,3-dihydro-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-3-(Acetyloxy)-5-(2-aminoethyl)-2,3-dihydro-2- (4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: Highly Purified. CAS No. 159734-23-3. Pack Sizes: 100mg. Molecular Formula: C19H20N2O4S. US Biological Life Sciences. USBiological 8
Worldwide
N,N,O-Tridesmethyl Diltiazem A metabolite of Diltiazem. Synonyms: (2S,3S)-3-(Acetyloxy)-5-(2-aminoethyl)-2,3-dihydro-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-3-(Acetyloxy)-5-(2-aminoethyl)-2,3-dihydro-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one. Grades: > 95%. CAS No. 159734-23-3. Molecular formula: C19H20N2O4S. Mole weight: 372.44. BOC Sciences 6
O-Desacetyl-N-desmethyl Diltiazem O-Desacetyl-N-desmethyl Diltiazem. Uses: For analytical and research use. Group: Impurity standards. CAS No. 81353-09-5. IUPAC Name: 3-hydroxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one. Molecular Formula: C19H22N2O3S. Mole Weight: 358.45. Catalog: APS81353095. SMILES: CNCCN1C (=O)C (O)C (Sc2ccccc12)c3ccc (OC)cc3. Format: Neat. Alfa Chemistry Analytical Products
O-Desmethyl diltiazem hydrochloride O-Desmethyl diltiazem hydrochloride. Group: Biochemicals. Alternative Names: (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride; (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride. Grades: Highly Purified. CAS No. 142926-07-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H25ClN2O4S. US Biological Life Sciences. USBiological 7
Worldwide

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