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| Product | Description | |
|---|---|---|
| 10-deoxymethynolide desosaminyltransferase | DesVII is the glycosyltransferase responsible for the attachment of dTDP-D-desosamine to 10-deoxymethynolide or narbonolide during the biosynthesis of methymycin, neomethymycin, narbomycin, and pikromycin in the bacterium Streptomyces venezuelae. Activity requires an additional protein partner, DesVIII. Group: Enzymes. Synonyms: glycosyltransferase DesVII; DesVII. Enzyme Commission Number: EC 2.4.1.277. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2509; 10-deoxymethynolide desosaminyltransferase; EC 2.4.1.277; glycosyltransferase DesVII; DesVII. Cat No: EXWM-2509. |  |
| 10-deoxymethynolide synthase | The product, 10-deoxymethynolide, contains a 12-membered ring and is an intermediate in the biosynthesis of methymycin in the bacterium Streptomyces venezuelae. The enzyme also produces narbonolide (see EC 2.3.1.240, narbonolide synthase). The enzyme has 29 active sites arranged in four polypeptides (pikAI - pikAIV) with a loading domain, six extension modules and a terminal thioesterase domain. Each extension module contains a ketosynthase (KS), keto reductase (KR), an acyltransferase (AT) and an acyl-carrier protein (ACP). Not all active sites are used in the biosynthesis. Group: Enzymes. Synonyms: pikromycin PKS. Enzyme Commission Number: EC 2.3.1.239. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2187; 10-deoxymethynolide synthase; EC 2.3.1.239; pikromycin PKS. Cat No: EXWM-2187. | |
| 11-oxo-β-amyrin 30-oxidase | A heme-thiolate protein (cytochrome P-450). The enzyme is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin in the plant Glycyrrhiza uralensis (licorice). The enzyme from the plant Medicago truncatula can also hydroxylate β-amyrin. Group: Enzymes. Synonyms: CYP72A; CYP72A154. Enzyme Commission Number: EC 1.14.13.173. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0771; 11-oxo-β-amyrin 30-oxidase; EC 1.14.13.173; CYP72A; CYP72A154. Cat No: EXWM-0771. | |
| (11Z)-hexadec-11-enoyl-CoA conjugase | The enzyme, characterized from the silk moth Bombyx mori, catalyses a step in the pathway for the biosynthesis of bombykol, a sex pheromone produced by the moth. The enzyme converts a single cis double bond at position 11 of (11Z)-hexadec-11-enoyl-CoA into conjugated 10 trans and 12 cis double bonds. Prior to catalysing this reaction, the enzyme catalyses the introduction of the cis bond in position 11 (cf. EC 1.14.19.5, acyl-CoA 11-desaturase). Group: Enzymes. Synonyms: Bmpgdesat1 (gene name). Enzyme Commission Number: EC 1.14.19.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0977; (11Z)-hexadec-11-enoyl-CoA conjugase; EC 1.14.19.15; Bmpgdesat1 (gene name). Cat No: EXWM-0977. | |
| 1, 2, 3, 4-Tetrahydro-7- (trifluoromethyl) isoquinoline Hydrochloride | 1, 2, 3, 4-Tetrahydro-7- (trifluoromethyl) isoquinoline Hydrochloride are potent inhibitors of phenylethanolamine N-methyltransferase, enzyme involved in the biosynthesis of epinephrine. Group: Biochemicals. Grades: Highly Purified. CAS No. 220247-87-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H10F3N HCl, Molecular Weight: 201.193646. US Biological Life Sciences. |  Worldwide |
| 1,2-dihydrovomilenine reductase | Forms part of the ajmaline biosynthesis pathway. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.73. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1342; 1,2-dihydrovomilenine reductase; EC 1.3.1.73. Cat No: EXWM-1342. | |
| 1,3-propanediol dehydrogenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,3-diol:NAD+ 1-oxidoreductase. Other names in common use include 3-hydroxypropionaldehyde reductase, 1,3-PD:NAD+ oxidoreductase, 1,3-propanediol:NAD+ oxidoreductase, and 1,3-propanediol dehydrogenase. This enzyme participates in ether lipid metabolism as a step in glycerolipid biosynthesis. Group: Enzymes. Synonyms: 3-hydroxypropionaldehyde reductase; 1,3-PD:NAD+ oxidoreductase; 1,3-propanediol:NAD+ oxidoreductase; 1,3-propanediol dehydrogenase. Enzyme Commission Number: EC 1.1.1.202. CAS No. 81611-70-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0107; 1,3-propanediol dehydrogenase; EC 1.1.1.202; 81611-70-3; 3-hydroxypropionaldehyde reductase; 1,3-PD:NAD+ oxidoreductase; 1,3-propanediol:NAD+ oxidoreductase; 1,3-propanediol dehydrogenase. Cat No: EXWM-0107. | |
| 1,4-dihydroxy-2-naphthoyl-CoA synthase | This enzyme is involved in the synthesis of 1,4-dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria), phylloquinone (vitamin K1 in plants), and many plant pigments.The coenzyme A group is subsequently removed from the product by EC 3.1.2.28, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase. Group: Enzymes. Synonyms: naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Enzyme Commission Number: EC 4.1.3.36. CAS No. 61328-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4913; 1,4-dihydroxy-2-naphthoyl-CoA synthase; EC 4.1.3.36; 61328-42-5; naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Cat No: EXWM-4913. | |
| 15-cis-phytoene desaturase | This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria. The enzyme from Synechococcus can also use NAD+ and NADP+ as electron acceptor under anaerobic conditions. The enzyme from Gentiana lutea shows no activity with NAD+ or NADP+. Group: Enzymes. Synonyms: phytoene desaturase (ambiguous); PDS; plant-type phytoene desaturase. Enzyme Commission Number: EC 1.3.5.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1389; 15-cis-phytoene desaturase; EC 1.3.5.5; phytoene desaturase (ambiguous); PDS; plant-type phytoene desaturase. Cat No: EXWM-1389. | |
| 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase | Involved in histidine biosynthesis. Group: Enzymes. Synonyms: N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase; phosphoribosyl formiminoaminophosphoribosyl imidazolecarboxamide isomerase; N-(phosphoribosylformimino) aminophosphoribosyl imidazolecarboxamide isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide ketol-isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosyla. Enzyme Commission Number: EC 5.3.1.16. CAS No. 37318-43-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5457; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase; EC 5.3.1.16; 37318-43-7; N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase; phosphoribosyl formiminoaminophosphoribosyl imidazolecarboxamide isomerase; N-(phosphoribosylformimino) aminophosphoribosyl imidazolecarboxamide isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide ketol-isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase. Cat No: EXWM-5457. | |
| 17α-hydroxyprogesterone deacetylase | A microsomal cytochrome P-450 (heme-thiolate) protein that catalyses two independent reactions at the same active site - the 17-hydroxylation of pregnenolone and progesterone, which is part of glucocorticoid hormones biosynthesis (EC 1.14.14.19), and the conversion of the 17-hydroxylated products via a 17,20-lyase reaction to form androstenedione and 3β-hydroxyandrost-5-en-17-one, leading to sex hormone biosynthesis. The activity of this reaction is dependent on the allosteric interaction of the enzyme with cytochrome b5 without any transfer of electrons from the cytochrome. The enzymes from different organisms differ in their substrate specificity. While the enzyme...son do not accept the former, and the enzyme from guinea pig does not accept the latter. Group: Enzymes. Synonyms: C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Enzyme Commission Number: EC 1.14.14.32. CAS No. 62213-24-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0930; 17α-hydroxyprogesterone deacetylase; EC 1.14.14.32; 62213-24-5; C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Cat No: EXWM-0930. | |
| 1-(Benzo[b]thien-2-yl)ethanol | 1-(Benzo[b]thien-2-yl)ethanol is an intermediate used to prepare amino sugar and related sugar derivatives of indolopyrrolocarbazole s as antitumors. It is also an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Zileuton is used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 51868-95-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C10H10OS, Molecular Weight: 178.25. US Biological Life Sciences. | Worldwide |
| 1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one | 1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one is an impurity of Mesotrione (M225765), a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C15H8N2O6S. US Biological Life Sciences. | Worldwide |
| 1-deoxy-11β-hydroxypentalenate dehydrogenase | Isolated from the bacterium Streptomyces avermitilis and present in many other Streptomyces species. Part of the pathway for pentalenolactone biosynthesis. Group: Enzymes. Synonyms: 1-deoxy-11β-hydroxypentalenic acid dehydrogenase; ptlF (gene name); penF (gene name). Enzyme Commission Number: EC 1.1.1.340. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0255; 1-deoxy-11β-hydroxypentalenate dehydrogenase; EC 1.1.1.340; 1-deoxy-11β-hydroxypentalenic acid dehydrogenase; ptlF (gene name); penF (gene name). Cat No: EXWM-0255. | |
| 1-deoxy-D-xylulose-5-phosphate reductoisomerase | The enzyme requires Mn2+, Co2+ or Mg2+ for activity, with the first being most effective. The enzyme from several eubacteria, including Escherichia coli, forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). The mechanism has been shown to be a retroaldol/aldol reaction. Group: Enzymes. Synonyms: DXP-reductoisomerase; 1-deoxy-D-xylulose-5-phosphate isomeroreductase; 2-C-methyl-D-erythritol 4-phosphate (MEP) synthase. Enzyme Commission Number: EC 1.1.1.267. CAS No. 210756-42-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0173; 1-deoxy-D-xylulose-5-phosphate reductoisomerase; EC 1.1.1.267; 210756-42-6; DXP-reductoisomerase; 1-deoxy-D-xylulose-5-phosphate isomeroreductase; 2-C-methyl-D-erythritol 4-phosphate (MEP) synthase. Cat No: EXWM-0173. | |
| 1-deoxy-D-xylulose-5-phosphate synthase | Requires thiamine diphosphate. The enzyme forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); DXP-synthase. Enzyme Commission Number: EC 2.2.1.7. CAS No. 202218-79-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2034; 1-deoxy-D-xylulose-5-phosphate synthase; EC 2.2.1.7; 202218-79-9; 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); DXP-synthase. Cat No: EXWM-2034. | |
| 1-deoxypentalenic acid 11β-hydroxylase | The enzyme requires Fe(II) and ascorbate. Isolated from the bacterium Streptomyces avermitilis. Part of the pathway for pentalenolactone biosynthesis. Group: Enzymes. Synonyms: ptlH (gene name); sav2991 (gene name); pntH (gene name). Enzyme Commission Number: EC 1.14.11.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0653; 1-deoxypentalenic acid 11β-hydroxylase; EC 1.14.11.35; ptlH (gene name); sav2991 (gene name); pntH (gene name). Cat No: EXWM-0653. | |
| 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase | The enzyme, isolated from the archaeon Haloarcula japonica, is involved in the biosynthesis of the C50 carotenoid bacterioruberin. In this pathway it catalyses the desaturation of the C-3,4 double bond in dihydroisopentenyldehydrorhodopin and the desaturation of the C-3',4' double bond in dihydrobisanhydrobacterioruberin. Group: Enzymes. Synonyms: crtD (gene name). Enzyme Commission Number: EC 1.3.99.37. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1437; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase; EC 1.3.99.37; crtD (gene name). Cat No: EXWM-1437. | |
| 1L-myo-inositol 1-phosphate cytidylyltransferase | In many organisms this activity is catalysed by a bifunctional enzyme. The cytidylyltransferase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 (CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase) is absolutely specific for CTP and 1L-myo-inositol 1-phosphate. The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate, a widespread organic solute in microorganisms adapted to hot environments. Group: Enzymes. Synonyms: CTP:inositol-1-phosphate cytidylyltransferase (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)); IPCT (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phospha. Enzyme Commission Number: EC 2.7.7.74. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3286; 1L-myo-inositol 1-phosphate cytidylyltransferase; EC 2.7.7.74; CTP:inositol-1-phosphate cytidylyltransferase (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)); IPCT (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)); L-myo-inositol-1-phosphate cytidylyltransferase. Cat No: EXWM-3286. | |
| 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase | Involved in the biosynthesis of lysine in bacteria (including cyanobacteria) and higher plants. The 1992 edition of the Enzyme List erroneously gave the name 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase to this enzyme. Group: Enzymes. Synonyms: tetrahydropicolinate succinylase; tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate succinyltransferase; succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase; succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. Enzyme Commission Number: EC 2.3.1.117. CAS No. 88086-34-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2056; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; EC 2.3.1.117; 88086-34-4; tetrahydropicolinate succinylase; tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate succinyltransferase; succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase; succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. Cat No: EXWM-2056. | |
| 2,3',4,6-tetrahydroxybenzophenone synthase | Involved in the biosynthesis of plant xanthones. Benzoyl-CoA can replace 3-hydroxybenzoyl-CoA (cf. EC 2.3.1.220, 2,4,6-trihydroxybenzophenone synthase). Group: Enzymes. Synonyms: benzophenone synthase (ambiguous); BPS (ambiguous). Enzyme Commission Number: EC 2.3.1.151. CAS No. 175780-21-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2091; 2,3',4,6-tetrahydroxybenzophenone synthase; EC 2.3.1.151; 175780-21-9; benzophenone synthase (ambiguous); BPS (ambiguous). Cat No: EXWM-2091. | |
| 2-(3-amino-3-carboxypropyl)histidine synthase | A [4Fe-4S] enzyme that modifies a histidine residue of the translation elongation factor 2 (EF2) via a 3-amino-3-carboxypropyl radical. The enzyme is present in archae and eukaryotes but not in eubacteria. The relevant histidine of EF2 is His715 in mammals, His699 in yeast and His600 in Pyrococcus horikoshii. Part of diphthamide biosynthesis. Group: Enzymes. Synonyms: Dph2. Enzyme Commission Number: EC 2.5.1.108. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2724; 2-(3-amino-3-carboxypropyl)histidine synthase; EC 2.5.1.108; Dph2. Cat No: EXWM-2724. | |
| 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H] | A flavoprotein (FAD). The enzyme from the archaeon Thermoplasma acidophilum is involved in the biosynthesis of membrane lipids. In vivo the reaction occurs in the reverse direction with the formation of 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate. cf. EC 1.3.7.11, 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase. Group: Enzymes. Synonyms: digeranylgeranylglycerophospholipid reductase; Ta0516m (gene name); DGGGPL reductase; 2,3-digeranylgeranylglycerophospholipid reductase. Enzyme Commission Number: EC 1.3.1.101. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1273; 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]; EC 1.3.1.101; digeranylgeranylglycerophospholipid reductase; Ta0516m (gene name); DGGGPL reductase; 2,3-digeranylgeranylglycerophospholipid reductase. Cat No: EXWM-1273. | |
| 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase | A flavoprotein (FAD). The enzyme is involved in the biosynthesis of archaeal membrane lipids. It catalyses the reduction of all 8 double bonds in 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipids and all 4 double bonds in 3-O-geranylgeranyl-sn-glycerol phospholipids with comparable activity. Unlike EC 1.3.1.101, 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H], this enzyme shows no activity with NADPH, and requires a dedicated ferredoxin. Group: Enzymes. Synonyms: AF0464 (gene name); 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase (donor). Enzyme Commission Number: EC 1.3.7.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1392; 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase; EC 1.3.7.11; AF0464 (gene name); 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase (donor). Cat No: EXWM-1392. | |
| 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. This enzyme is also called 2,3-DHB dehydrogenase. This enzyme participates in biosynthesis of siderophore group nonribosomal. Group: Enzymes. Synonyms: 2,3-DHB dehydrogenase; 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.3.1.28. CAS No. 37250-40-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1301; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; EC 1.3.1.28; 37250-40-1; 2,3-DHB dehydrogenase; 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. Cat No: EXWM-1301. | |
| 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid | 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate. Synonyms: 2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot. CAS No. 955373-67-8. Molecular formula: C7H6O4S. Mole weight: 186.181. |  |
| (2,3-dihydroxybenzoyl)adenylate synthase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:2,3-dihydroxybenzoate adenylyltransferase. This enzyme is also called 2,3-dihydroxybenzoate-AMP ligase. This enzyme participates in biosynthesis of siderophore group nonribosomal. Group: Enzymes. Synonyms: 2,3-dihydroxybenzoate-AMP ligase. Enzyme Commission Number: EC 2.7.7.58. CAS No. 122332-73-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3269; (2,3-dihydroxybenzoyl)adenylate synthase; EC 2.7.7.58; 122332-73-4; 2,3-dihydroxybenzoate-AMP ligase. Cat No: EXWM-3269. | |
| 2,4,6-trihydroxybenzophenone synthase | Involved in the biosynthesis of plant xanthones. The enzyme from the plant Hypericum androsaemum L can use 3-hydroxybenzoyl-CoA instead of benzoyl-CoA, but with lower activity (cf. EC 2.3.1.151, 2,3',4,6-tetrahydroxybenzophenone synthase). Group: Enzymes. Synonyms: benzophenone synthase (ambiguous); BPS (ambiguous). Enzyme Commission Number: EC 2.3.1.220. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2167; 2,4,6-trihydroxybenzophenone synthase; EC 2.3.1.220; benzophenone synthase (ambiguous); BPS (ambiguous). Cat No: EXWM-2167. | |
| 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase | The enzyme is involved in the biosynthesis of the protective and allelophatic benzoxazinoid DIMBOA [(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin] in some plants, most commonly from the family of Poaceae (grasses). Group: Enzymes. Synonyms: BX7 (gene name); OMT BX7. Enzyme Commission Number: EC 2.1.1.241. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1844; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase; EC 2.1.1.241; BX7 (gene name); OMT BX7. Cat No: EXWM-1844. | |
| 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase | The enzyme is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants, most commonly from the family of Poaceae (grasses). Group: Enzymes. Synonyms: BX6 (gene name); DIBOA-Glc dioxygenase. Enzyme Commission Number: EC 1.14.20.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1018; 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase; EC 1.14.20.2; BX6 (gene name); DIBOA-Glc dioxygenase. Cat No: EXWM-1018. | |
| 24-methylenesterol C-methyltransferase | This is the second methylation step of plant sterol biosynthesis (cf EC 2.1.1.142, cycloartenol 24-C-methyltransferase). Group: Enzymes. Synonyms: SMT2; 24-methylenelophenol C-241-methyltransferase. Enzyme Commission Number: EC 2.1.1.143. CAS No. 67165-89-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1739; 24-methylenesterol C-methyltransferase; EC 2.1.1.143; 67165-89-3; SMT2; 24-methylenelophenol C-241-methyltransferase. Cat No: EXWM-1739. | |
| 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase | The enzyme participates in a folate biosynthesis pathway in Chlamydia. Group: Enzymes. Enzyme Commission Number: EC 4.2.1.160. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5001; 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase; EC 4.2.1.160. Cat No: EXWM-5001. | |
| 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase | The reaction proceeds in the opposite direction. A step in riboflavin biosynthesis, NADPH and NADH function equally well as reductant. Differs from EC 1.1.1.193 [5-amino-6-(5-phosphoribosylamino)uracil reductase] since it does not catalyse the reduction of 5-amino-6-ribosylaminopyrimidine-2,4(1H,3H)-dione 5'-phosphate. Group: Enzymes. Synonyms: 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; MjaRED; MJ0671 (gene name). Enzyme Commission Number: EC 1.1.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0213; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase; EC 1.1.1.302; 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; MjaRED; MJ0671 (gene name). Cat No: EXWM-0213. | |
| 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase | Specifically methylates 2,4',7-trihydroxyisoflavanone on the 4'-position. No activity with isoflavones. The enzyme is involved in formononetin biosynthesis in legumes. The protein from pea (Pisum sativum) also methylates (+)-6a-hydroxymaackiain at the 3-position (cf. EC 2.1.1.270, (+)-6a-hydroxymaackiain 3-O-methyltransferase). Group: Enzymes. Synonyms: SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.212. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1814; 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; EC 2.1.1.212; SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Cat No: EXWM-1814. | |
| 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | The enzyme from the bacterium Streptomyces carzinostaticus is involved in the biosynthesis of 2-hydroxy-7-methoxy-5-methyl-1-naphthoate. This compound is part of the enediyne chromophore of the antitumor antibiotic neocarzinostatin. In vivo the enzyme catalyses the regiospecific methylation at the 7-hydroxy group of its native substrate 2,7-dihydroxy-5-methyl-1-naphthoate. In vitro it also recognizes other dihydroxynaphthoic acids and catalyses their regiospecific O-methylation. Group: Enzymes. Synonyms: NcsB1; neocarzinostatin O-methyltransferase. Enzyme Commission Number: EC 2.1.1.303. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1911; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase; EC 2.1.1.303; NcsB1; neocarzinostatin O-methyltransferase. Cat No: EXWM-1911. | |
| 27-O-demethylrifamycin SV methyltransferase | The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the antitubercular drug rifamycin B. Group: Enzymes. Synonyms: AdoMet:27-O-demethylrifamycin SV methyltransferase. Enzyme Commission Number: EC 2.1.1.315. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1923; 27-O-demethylrifamycin SV methyltransferase; EC 2.1.1.315; AdoMet:27-O-demethylrifamycin SV methyltransferase. Cat No: EXWM-1923. | |
| 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase | The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme can also catalyse the reaction of EC 4.1.2.13, fructose-bisphosphate aldolase. Group: Enzymes. Synonyms: ADH synthase; ADHS; MJ0400 (gene name). Enzyme Commission Number: EC 2.2.1.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2026; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; EC 2.2.1.10; ADH synthase; ADHS; MJ0400 (gene name). Cat No: EXWM-2026. | |
| 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase | Part of the pathway for the biosynthesis of grixazone, a mixture of yellow pigments produced by the bacterium Streptomyces griseus. Group: Enzymes. Synonyms: griI (gene name). Enzyme Commission Number: EC 4.1.2.56. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4893; 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase; EC 4.1.2.56; griI (gene name). Cat No: EXWM-4893. | |
| 2-amino-4-deoxychorismate synthase | Requires Mg2+. The reaction occurs in the reverse direction to that shown above. In contrast to most anthranilate-synthase I (ASI) homologues, this enzyme is not inhibited by tryptophan. In Streptomyces globisporus, the sequential action of this enzyme and EC 1.3.99.24, 2-amino-4-deoxychorismate dehydrogenase, leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027.In certain Pseudomonads the enzyme participates in the biosynthesis of phenazine, a precursor for several compounds with antibiotic activity. Group: Enzymes. Synonyms: ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Enzyme Commission Number: EC 2.6.1.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2927; 2-amino-4-deoxychorismate synthase; EC 2.6.1.86; ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Cat No: EXWM-2927. | |
| 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase | The enzyme catalyses the second step in archaeal riboflavin and 7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis. The first step is catalysed by EC 3.5.4.29 (GTP cyclohydrolase IIa). The bacterial enzyme, EC 3.5.4.25 (GTP cyclohydrolase II) catalyses both reactions. Group: Enzymes. Synonyms: ArfB. Enzyme Commission Number: EC 3.5.1.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4381; 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase; EC 3.5.1.102; ArfB. Cat No: EXWM-4381. | |
| 2-Bromo-6- (3- (methylsulfonyl) -4-nitrophenoxy) benzaldehyde | 2-Bromo-6- (3- (methylsulfonyl) -4-nitrophenoxy) benzaldehyde is an intermediate in the synthesis of 1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one (C981885), which is an impurity of Mesotrione (M225765), a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C14H10BrNO6S. US Biological Life Sciences. | Worldwide |
| 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | The enzyme from Escherichia coli requires Mg2+ or Mn2+. Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: MECDP-synthase; 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing). Enzyme Commission Number: EC 4.6.1.12. CAS No. 287480-92-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5349; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; EC 4.6.1.12; 287480-92-6; MECDP-synthase; 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing). Cat No: EXWM-5349. | |
| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | The enzyme from Escherichia coli requires Mg2+ or Mn2+. ATP or UTP can replace CTP, but both are less effective. GTP and TTP are not substrates. Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: MEP cytidylyltransferase. Enzyme Commission Number: EC 2.7.7.60. CAS No. 251990-59-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3272; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; EC 2.7.7.60; 251990-59-7; MEP cytidylyltransferase. Cat No: EXWM-3272. | |
| 2-dehydropantoate 2-reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-pantoate:NADP+ 2-oxidoreductase. Other names in common use include 2-oxopantoate reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, ketopantoate reductase, and ketopantoic acid reductase. This enzyme participates in pantothenate and coa biosynthesis. Group: Enzymes. Synonyms: 2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase. Enzyme Commission Number: EC 1.1.1.169. CAS No. 37211-74-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0072; 2-dehydropantoate 2-reductase; EC 1.1.1.169; 37211-74-8; 2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase. Cat No: EXWM-0072. | |
| 2-dehydropantolactone reductase | The enzyme participates in an alternative pathway for biosynthesis of (R)-pantothenate (vitamin B5). This entry covers enzymes whose stereo specificity for NADP+ is not known. cf. EC 1.1.1.168 2-dehydropantolactone reductase (Re-specific) and EC 1.1.1.214, 2-dehydropantolactone reductase (Si-specific). Group: Enzymes. Synonyms: 2-oxopantoyl lactone reductase; 2-ketopantoyl lactone reductase; ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase. Enzyme Commission Number: EC 1.1.1.358. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0274; 2-dehydropantolactone reductase; EC 1.1.1.358; 2-oxopantoyl lactone reductase; 2-ketopantoyl lactone reductase; ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase. Cat No: EXWM-0274. | |
| 2'-Deoxyguanosine 5'phosphate tetrahydrate disodium salt | 2'-Deoxyguanosine 5'phosphate tetrahydrate disodium salt, a molecular biology research compound, plays a critical role in the enzymatic synthesis of DNA or RNA molecules. As a precursor for purine nucleotide biosynthesis, it facilitates vital cellular processes such as DNA replication, gene expression, and signal transduction. Additionally, its ability to act as a substrate for enzymes involved in DNA repair and genetic recombination underscores its significance in biological research. Synonyms: disodium deoxyguanosine-5'-phosphate tetrahydrate. Grades: 98%. CAS No. 52558-16-4. Molecular formula: C10H20N5Na2O11P. Mole weight: 463.25. | |
| 2-deoxystreptamine glucosyltransferase | Involved in the biosynthesis of kanamycin B and kanamycin C. Also catalyses EC 2.4.1.283, 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase, but activity is only one fifth of that with UDP-α-D-glucose. Group: Enzymes. Synonyms: kanF (gene name). Enzyme Commission Number: EC 2.4.1.284. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2517; 2-deoxystreptamine glucosyltransferase; EC 2.4.1.284; kanF (gene name). Cat No: EXWM-2517. | |
| 2-epi-5-epi-valiolone 7-kinase | The enzyme, characterized from the bacterium Actinoplanes sp. SE50/110, is involved in the biosynthesis of the oligosaccharide acarbose. Group: Enzymes. Synonyms: AcbM. Enzyme Commission Number: EC 2.7.1.188. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3020; 2-epi-5-epi-valiolone 7-kinase; EC 2.7.1.188; AcbM. Cat No: EXWM-3020. | |
| 2-epi-5-epi-valiolone 7-phosphate 2-epimerase | The enzyme, isolated from the bacterium Actinoplanes sp. SE 50/110, is involved in the biosynthesis of the α-glucosidase inhibitor acarbose. Group: Enzymes. Synonyms: AcbO. Enzyme Commission Number: EC 5.1.3.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5422; 2-epi-5-epi-valiolone 7-phosphate 2-epimerase; EC 5.1.3.35; AcbO. Cat No: EXWM-5422. | |
| 2-epi-5-epi-valiolone epimerase | The enzyme, characterized from the bacterium Actinomyces sp. Lu 9419, is involved in the biosynthesis of the antitumor agent cetoniacytone A. Group: Enzymes. Synonyms: CetB; EVE. Enzyme Commission Number: EC 5.1.3.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5420; 2-epi-5-epi-valiolone epimerase; EC 5.1.3.33; CetB; EVE. Cat No: EXWM-5420. | |
| 2-epi-5-epi-valiolone synthase | The enzyme is highly specific for α-D-sedoheptulopyranose 7-phosphate. It requires a divalent metal ion (Zn2+ or Co2+) and an NAD+ cofactor, which is transiently reduced during the reaction. The enzyme is involved in the biosynthesis of C7N-aminocyclitol natural products, such as the valienamine moiety of the antidiabetic drug acarbose and the crop protectant validamycin A. cf. EC 4.2.3.155, 2-epi-valiolone synthase and EC 4.2.3.154, demethyl-4-deoxygadusol synthase. Group: Enzymes. Synonyms: AcbC; ValA; CetA; SalQ; C7-cyclitol synthase. Enzyme Commission Number: EC 4.2.3.152. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5167; 2-epi-5-epi-valiolone synthase; EC 4.2.3.152; AcbC; ValA; CetA; SalQ; C7-cyclitol synthase. Cat No: EXWM-5167. | |
| 2-epi-valiolone synthase | The enzyme, characterized from the bacteria Actinosynnema mirum and Stigmatella aurantiaca DW4/3-1, produces 2-epi-valiolone, which is believed to function as a precursor in aminocyclitol biosynthesis. It requires a divalent metal ion (Zn2+ or Co2+) and an NAD+ cofactor, which is transiently reduced during the reaction. cf. EC 4.2.3.152, 2-epi-5-epi-valiolone synthase and EC 4.2.3.154, demethyl-4-deoxygadusol synthase. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.155. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5170; 2-epi-valiolone synthase; EC 4.2.3.155. Cat No: EXWM-5170. | |
| 2-heptyl-3-hydroxy-4(1H)-quinolone synthase | The enzyme from the bacterium Pseudomonas aeruginosa catalyses the terminal step in biosynthesis of the signal molecule 2-heptyl-3,4-dihydroxyquinoline that plays a role in regulation of virulence genes. Group: Enzymes. Synonyms: PqsH; 2-heptyl-3,4-dihydroxyquinoline synthase. Enzyme Commission Number: EC 1.14.13.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0781; 2-heptyl-3-hydroxy-4(1H)-quinolone synthase; EC 1.14.13.182; PqsH; 2-heptyl-3,4-dihydroxyquinoline synthase. Cat No: EXWM-0781. | |
| 2-heptyl-4(1H)-quinolone synthase | The enzyme from the Gram-negative bacterium Pseudomonas aeruginosa is involved in the biosynthesis of 2-heptyl-4-hydroxyquinoline and 2,4-dihydroxyquinoline. 2-Heptyl-4-hydroxyquinoline is a signal molecule, that is involved in regulation of virulence factor production and biofilm formation. The enzyme shows a broad specificity and is involved in the synthesis of a wide array of additional 2-alkyl-4(1H)-quinolones synthesized by the organism. Group: Enzymes. Enzyme Commission Number: EC 2.3.1.230. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2178; 2-heptyl-4(1H)-quinolone synthase; EC 2.3.1.230. Cat No: EXWM-2178. | |
| 2-hydroxy-1,4-benzoxazin-3-one monooxygenase | The enzyme is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants, most commonly from the family of Poaceae (grasses). It is a member of the cytochrome P-450 dependent monooxygenases. Group: Enzymes. Synonyms: BX5 (gene name); CYP71C3 (gene name). Enzyme Commission Number: EC 1.14.13.140. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0740; 2-hydroxy-1,4-benzoxazin-3-one monooxygenase; EC 1.14.13.140; BX5 (gene name); CYP71C3 (gene name). Cat No: EXWM-0740. | |
| 2'-hydroxydaidzein reductase | In the reverse reaction, the 2'-hydroxyisoflavone (2'-hydroxydaidzein) is reduced to an isoflavanone. Also acts on 2'-hydroxyformononetin and to a small extent on 2'-hydroxygenistein. Involved in the biosynthesis of the phytoalexin glyceollin. The isoflavones biochanin A, daidzein and genestein as well as the flavonoids apigenin, kaempferol and quercetin do not act as substrates. Group: Enzymes. Synonyms: NADPH:2'-hydroxydaidzein oxidoreductase; HDR; 2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase. Enzyme Commission Number: EC 1.3.1.51. CAS No. 126125-01-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1323; 2'-hydroxydaidzein reductase; EC 1.3.1.51; 126125-01-7; NADPH:2'-hydroxydaidzein oxidoreductase; HDR; 2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase. Cat No: EXWM-1323. | |
| 2-hydroxyethylphosphonate dioxygenase | Requires non-heme-Fe(II). Isolated from some bacteria including Streptomyces hygroscopicus and Streptomyces viridochromogenes. The pro-R hydrogen at C-2 of the ethyl group is retained by the formate ion. Any stereochemistry at C-1 of the ethyl group is lost. One atom from dioxygen is present in each product. Involved in phosphinothricin biosynthesis. Group: Enzymes. Synonyms: HEPD; phpD (gene name); 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming). Enzyme Commission Number: EC 1.13.11.72. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0592; 2-hydroxyethylphosphonate dioxygenase; EC 1.13.11.72; HEPD; phpD (gene name); 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming). Cat No: EXWM-0592. | |
| 2-hydroxyethylphosphonate methyltransferase | Requires cobalamin. The enzyme, isolated from the bacterium Streptomyces wedmorensis, is a member of the 'AdoMet radical' (radical SAM) family. Involved in fosfomycin biosynthesis. Group: Enzymes. Synonyms: Fom3. Enzyme Commission Number: EC 2.1.1.308. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1916; 2-hydroxyethylphosphonate methyltransferase; EC 2.1.1.308; Fom3. Cat No: EXWM-1916. | |
| 2'-hydroxyisoflavone reductase | In the reverse reaction, a 2'-hydroxyisoflavone is reduced to an isoflavanone; 2'-hydroxypseudobaptigenin also acts. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. Group: Enzymes. Synonyms: NADPH:2'-hydroxyisoflavone oxidoreductase; isoflavone reductase; 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase. Enzyme Commission Number: EC 1.3.1.45. CAS No. 128449-69-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1317; 2'-hydroxyisoflavone reductase; EC 1.3.1.45; 128449-69-4; NADPH:2'-hydroxyisoflavone oxidoreductase; isoflavone reductase; 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase. Cat No: EXWM-1317. | |
| 2-iminoacetate synthase | Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule. The first stage of catalysis is reduction of the S-adenosyl-L-methionine to produce methionine and a 5-deoxyadenosin-5-yl radical that is crucial for the conversion of the substrate. The reductant is assumed to be NADPH, which is provided by a flavoprotein:NADPH oxidoreductase system. Part of the pathway for thiamine biosynthesis. Group: Enzymes. Synonyms: thiH (gene name). Enzyme Commission Number: EC 4.1.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4932; 2-iminoacetate synthase; EC 4.1.99.19; thiH (gene name). Cat No: EXWM-4932. | |
| 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase | This enzyme is involved in ubiquinone biosynthesis. Ubiquinones from different organisms have a different number of prenyl units (for example, ubiquinone-6 in Saccharomyces, ubiquinone-9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units. For example, when the COQ5 gene from Saccharomyces cerevisiae is introduced into Escherichia coli, it complements the respiratory deficiency of an ubiE mutant. The bifunctional enzyme from Escherichia coli also catalyses the methylation of demethylmenaquinol-8 (this activity is classified as EC 2.1.1.163). Group: Enzymes. Synonyms: ubiE (gene name, ambiguous). Enzyme Commission Number: EC 2.1.1.201. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1802; 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; EC 2.1.1.201; ubiE (gene name, ambiguous). Cat No: EXWM-1802. | |
| 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase | Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols). Group: Enzymes. Synonyms: VTE3 (gene name); 2-methyl-6-solanyl-1,4-hydroquinone methyltransferase; MPBQ/MSBQ methyltransferase; MPBQ/MSBQ MT. Enzyme Commission Number: EC 2.1.1.295. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1902; 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase; EC 2.1.1.295; VTE3 (gene name); 2-methyl-6-solanyl-1,4-hydroquinone methyltransferase; MPBQ/MSBQ methyltransferase; MPBQ/MSBQ MT. Cat No: EXWM-1902. | |
| 2-methylbutanoate polyketide synthase | This polyketide synthase enzyme forms the (S)-2-methylbutanoate side chain during lovastatin biosynthesis by the filamentous fungus Aspergillus terreus. The overall reaction comprises a single condensation reaction followed by α-methylation, β-ketoreduction, dehydration, and α,β enoyl reduction. Group: Enzymes. Synonyms: LovF. Enzyme Commission Number: EC 2.3.1.244. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2193; 2-methylbutanoate polyketide synthase; EC 2.3.1.244; LovF. Cat No: EXWM-2193. | |
| 2'-O-ribosyladenosine (phosphate) | 2'-O-ribosyladenosine (phosphate), a significant enzyme in RNA production, modifies nucleotides in RNA formation for mRNA molecule production used in protein synthesis. In addition, the product is crucial for biosynthesis of purine, a crucial molecular base in DNA and RNA. With targeted inhibition of certain cancer cells, this potent tool finds wide application in cancer treatment research. Synonyms: Adenosine, 2'-O-(5-O-phosphono-b-D-ribofuranosyl)-; O-beta-ribosyl(1''--2')adenosine-5''-phosphate; 2'-O-(5-O-Phosphono-beta-D-ribofuranosyl)adenosine. CAS No. 28050-13-7. Molecular formula: C15H22N5O11P. Mole weight: 479.34. | |
| 2-phospho-L-lactate guanylyltransferase | This enzyme is involved in the biosynthesis of coenzyme F420, a redox-active cofactor found in all methanogenic archaea, as well as some eubacteria. Group: Enzymes. Synonyms: CofC; MJ0887. Enzyme Commission Number: EC 2.7.7.68. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3279; 2-phospho-L-lactate guanylyltransferase; EC 2.7.7.68; CofC; MJ0887. Cat No: EXWM-3279. | |
| 2-phospho-L-lactate transferase | This enzyme is involved in the biosynthesis of coenzyme F420, a redox-active cofactor found in all methanogenic archaea, as well as some eubacteria. Group: Enzymes. Synonyms: LPPG:Fo 2-phospho-L-lactate transferase; LPPG:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase; MJ1256; lactyl-2-diphospho-(5')guanosine:Fo 2-phospho-L-lactate transferase; CofD. Enzyme Commission Number: EC 2.7.8.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3327; 2-phospho-L-lactate transferase; EC 2.7.8.28; LPPG:Fo 2-phospho-L-lactate transferase; LPPG:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase; MJ1256; lactyl-2-diphospho-(5')guanosine:Fo 2-phospho-L-lactate transferase; CofD. Cat No: EXWM-3327. | |
| 2-polyprenyl-6-hydroxyphenol methylase | UbiG catalyses both methylation steps in ubiquinone biosynthesis in Escherichia coli. The second methylation is classified as EC 2.1.1.64 (3-demethylubiquinol 3-O-methyltransferase). In eukaryotes Coq3 catalyses the two methylation steps in ubiquinone biosynthesis. However, while the second methylation is common to both enzymes, the first methylation by Coq3 occurs at a different position within the pathway, and thus involves a different substrate and is classified as EC 2.1.1.114 (polyprenyldihydroxybenzoate methyltransferase). The substrate of the eukaryotic enzyme (3,4-dihydroxy-5-all-trans-polyprenylbenzoate) differs by an additional carboxylate moiety. Group: Enzymes. Synonyms: ubiG (gene name, ambiguous); ubiG methyltransferase (ambiguous); 2-octaprenyl-6-hydroxyphenol methylase. Enzyme Commission Number: EC 2.1.1.222. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1825; 2-polyprenyl-6-hydroxyphenol methylase; EC 2.1.1.222; ubiG (gene name, ambiguous); ubiG methyltransferase (ambiguous); 2-octaprenyl-6-hydroxyphenol methylase. Cat No: EXWM-1825. | |
| (2R)-3-sulfolactate dehydrogenase (NADP+) | The enzyme from the bacterium Chromohalobacter salexigens can only utilize NADP+. It functions both biosynthetically in coenzyme M biosynthesis and degradatively, in the degradation of sulfolactate. It can not use (S)-malate and (S)-lactate. Group: Enzymes. Synonyms: (R)-sulfolactate:NADP+ oxidoreductase; L-sulfolactate dehydrogenase; (R)-sulfolactate dehydrogenase; ComC. Enzyme Commission Number: EC 1.1.1.338. CAS No. 81210-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0252; (2R)-3-sulfolactate dehydrogenase (NADP+); EC 1.1.1.338; 81210-65-3; (R)-sulfolactate:NADP+ oxidoreductase; L-sulfolactate dehydrogenase; (R)-sulfolactate dehydrogenase; ComC. Cat No: EXWM-0252. | |
| 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | Requires Mg2+ for maximal activity. This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the products of the reaction were (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate (SHCHC), pyruvate and CO2 but it is now known that two separate enzymes are involved: this enzyme and EC 4.2.99.20, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. Under basic conditions, the product can spontaneously lose pyruvate to form SHCHC. Group: Enzymes. Synonyms: SEPHCHC synthase; MenD. Enzyme Commission Number: EC 2.2.1.9. CAS No. 1112282-73-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2036; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase; EC 2.2.1.9; 1112282-73-1; SEPHCHC synthase; MenD. Cat No: EXWM-2036. | |
| 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the reactions carried out by this enzyme and EC 2.2.1.9, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, were carried out by a single enzyme but this has since been disproved. Group: Enzymes. Synonyms: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Enzyme Commission Number: EC 4.2.99.20. CAS No. 122007-88-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5266; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; EC 4.2.99.20; 122007-88-9; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Cat No: EXWM-5266. | |
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