Biosynthesis Enzyme Suppliers USA
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Product | Description | |
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1, 2, 3, 4-Tetrahydro-7- (trifluoromethyl) isoquinoline Hydrochloride Quick inquiry Where to buy Suppliers range | 1, 2, 3, 4-Tetrahydro-7- (trifluoromethyl) isoquinoline Hydrochloride are potent inhibitors of phenylethanolamine N-methyltransferase, enzyme involved in the biosynthesis of epinephrine. Group: Biochemicals. Grades: Highly Purified. CAS No. 220247-87-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H10F3N HCl, Molecular Weight: 201.193646. US Biological Life Sciences. | Worldwide |
1-(Benzo[b]thien-2-yl)ethanol Quick inquiry Where to buy Suppliers range | 1-(Benzo[b]thien-2-yl)ethanol is an intermediate used to prepare amino sugar and related sugar derivatives of indolopyrrolocarbazole s as antitumors. It is also an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Zileuton is used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 51868-95-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C10H10OS, Molecular Weight: 178.25. US Biological Life Sciences. | Worldwide |
1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one Quick inquiry Where to buy Suppliers range | 1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one is an impurity of Mesotrione (M225765), a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C15H8N2O6S. US Biological Life Sciences. | Worldwide |
2,3,4,6-Tetra-O-acetyl-b-D-thioglucopyranose sodium salt Quick inquiry Where to buy Suppliers range | 2,3,4,6-Tetra-O-acetyl-b-D-thioglucopyranose sodium salt, a chemical compound frequently employed in the fabrication of biochemicals, functions as a fundamental substrate for enzymatic processes crucially implicated in glycoprotein biosynthesis. Its utilization plays a crucial part in the creation of therapeutic drugs that provide relief for diverse maladies ranging from cancer to diabetes. Molecular formula: C14H19O9SNa. Mole weight: 386.35. | |
2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid Quick inquiry Where to buy Suppliers range | 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate. Synonyms: 2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot. CAS No. 955373-67-8. Molecular formula: C7H6O4S. Mole weight: 186.181. | |
2,6-Dideoxy-2-fluoro-L-mannose Quick inquiry Where to buy Suppliers range | 2,6-Dideoxy-2-fluoro-L-mannose, a highly regarded compound in the field of biomedicine, serves as a crucial element in the extensive study of glycoprotein biosynthesis. As an epitome of a substrate analog, it diligently mimics the enzymatic functionalities required for such processes. Imposing its significance, this compound has proven invaluable in unraveling the intricate connections between glycosylation and various ailments, encompassing cancer, diabetes, and autoimmune disorders. To procure this pivotal compound, one can readily acquire it from reputable chemical suppliers with utmost reliability. Molecular formula: C6H11FO4. Mole weight: 166.15. | |
2-Bromo-6- (3- (methylsulfonyl) -4-nitrophenoxy) benzaldehyde Quick inquiry Where to buy Suppliers range | 2-Bromo-6- (3- (methylsulfonyl) -4-nitrophenoxy) benzaldehyde is an intermediate in the synthesis of 1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one (C981885), which is an impurity of Mesotrione (M225765), a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C14H10BrNO6S. US Biological Life Sciences. | Worldwide |
2'-Deoxyguanosine 5'phosphate tetrahydrate disodium salt Quick inquiry Where to buy Suppliers range | 2'-Deoxyguanosine 5'phosphate tetrahydrate disodium salt, a molecular biology research compound, plays a critical role in the enzymatic synthesis of DNA or RNA molecules. As a precursor for purine nucleotide biosynthesis, it facilitates vital cellular processes such as DNA replication, gene expression, and signal transduction. Additionally, its ability to act as a substrate for enzymes involved in DNA repair and genetic recombination underscores its significance in biological research. Synonyms: disodium deoxyguanosine-5'-phosphate tetrahydrate. Grades: 98%. CAS No. 52558-16-4. Molecular formula: C10H20N5Na2O11P. Mole weight: 463.25. | |
2'-O-ribosyladenosine (phosphate) Quick inquiry Where to buy Suppliers range | 2'-O-ribosyladenosine (phosphate), a significant enzyme in RNA production, modifies nucleotides in RNA formation for mRNA molecule production used in protein synthesis. In addition, the product is crucial for biosynthesis of purine, a crucial molecular base in DNA and RNA. With targeted inhibition of certain cancer cells, this potent tool finds wide application in cancer treatment research. Synonyms: Adenosine, 2'-O-(5-O-phosphono-b-D-ribofuranosyl)-; O-beta-ribosyl(1''--2')adenosine-5''-phosphate; 2'-O-(5-O-Phosphono-beta-D-ribofuranosyl)adenosine. CAS No. 28050-13-7. Molecular formula: C15H22N5O11P. Mole weight: 479.34. | |
(2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne Quick inquiry Where to buy Suppliers range | (2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne is a byproduct in the synthesis of Terbinafine Hydrochloride (T107500); an orally active, antimycotic allylamine related to Naftifine. It is a specific inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Also antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 635708-74-6. Pack Sizes: 10mg, 100mg. Molecular Formula: C?H??Cl, Molecular Weight: 156.65. US Biological Life Sciences. | Worldwide |
4-Chloro-DL-phenylalanine Quick inquiry Where to buy Suppliers range | 4-Chloro-DL-phenylalanine is a pharmaceutical intermediate. It acts as a selective and irreversible inhibitor of tryptophan hydroxylase. It is a rate-limiting enzyme in the biosynthesis of serotonin. It has been used experimentally to treat carcinoid syndrome. It is used in scientific research in humans and animals to investigate the effects of serotonin depletion. It binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain. Uses: 4-chloro-dl-phenylalanine has been used experimentally to treat carcinoid syndrome. it is used in scientific research in humans and animals to investigate the effects of serotonin depletion. it binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain. Synonyms: CP-10,188; CP10,188; CP 10,188; CP-10188; CP10188; CP 10188; Fenclonine; DL-3-(4-Chlorophenyl)alanine; Fenclonin; NSC 77370; p-Clorophenylalanine.; DL-4-Chlorophenylalanine;p-Chlorophenylalanine;(S)-2-amino-3-(4-chlorophenyl)propanoic acid;2-Amino-3-(4-chlorophenyl)propanoic acid; DL-3-(4-Chlorophenyl)alanine; Fenclonin; Fenclonine; PCP; PCPA; CP-10188. Grades: ≥ 99% (HPLC). CAS No. 7424-00-2. Molecular formula: C9H10ClNO2. Mole weight: 199.63. | |
4-Nitrophenyl 2-O-(2,3,4-tri-O-acetyl-b-L-fucopyranosyl)-6-O-benzoyl-a-D-galactopyranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl 2-O-(2,3,4-tri-O-acetyl-b-L-fucopyranosyl)-6-O-benzoyl-a-D-galactopyranoside is a compound used in biomedical research. It is commonly utilized as a substrate in enzymatic assays to study fucosyltransferase activity. This compound aids in the investigation of glycan biosynthesis and can be employed in the development of potential anti-cancer or anti-viral drugs targeting fucose-containing glycans. Molecular formula: C31H35NO16. Mole weight: 677.61. | |
6-Amino-2-(2-deoxy-β-D-ribofuranosyl)-2,5-dihydro-4H-pyrazolo-[3,4-d]-pyrimidin-4-one Quick inquiry Where to buy Suppliers range | 6-Amino-2-(2-deoxy-β-D-ribofuranosyl)-2,5-dihydro-4H-pyrazolo-[3,4-d]-pyrimidin-4-one, a robust antiviral compound, exhibits remarkable efficacy against diverse viral infections. Its distinctive mechanism of action involves targeted suppression of viral enzymes and disruption of nucleic acid biosynthesis. Grades: ≥ 95%. CAS No. 109737-94-2. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside Quick inquiry Where to buy Suppliers range | 6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside, a fundamental compound employed in the field of biomedicine, assumes a momentous function in the advancement of pharmacotherapy designed to combat bacterial infections. More specifically, it selectively targets and inhibits the enzymatic processes underlying the biosynthesis of bacterial cell wall, thereby exhibiting remarkable inhibitory efficacy across a diverse spectrum of bacterial strains. Synonyms: 6-Methyl-2-pyridyl N-acetyl-b-D-thioglucosamine MPT-NAG. CAS No. 149263-94-5. Molecular formula: C14H20N2O5S. Mole weight: 328.39. | |
(6R)-5,6,7,8-Tetrahydro-L-biopterin 2HCl Quick inquiry Where to buy Suppliers range | Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4; Sapropterin; Sapropterin dihydrochloride; BioMarin T 1401, Biopten, Kuvan, SUN 0588; Shiratori SN 0588. Grades: Highly Purified. CAS No. 69056-38-8,17528-72-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??N?O?; 2(HCl), Molecular Weight: 314.17. US Biological Life Sciences. | Worldwide |
8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - DYQ-661 Quick inquiry Where to buy Suppliers range | DYQ-661, a strikingly potent and exclusive inhibitor of CD73, a critical enzyme implicated in the biosynthesis of immunosuppressive adenosine in the tumor microenvironment, presents a hopeful alternative for patients with different types of cancer. The preclinical investigations depict handsome outcomes, enhancing the effectiveness of immune checkpoint inhibitors. DYQ-661 is an exceedingly promising therapeutic approach that demands significant attention in the realm of cancer treatment. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with DYQ 661, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H70N9O18P2S2 (Anion). Mole weight: 1271.27 (Anion). | |
8-Methoxycarbonyloctyl 2-acetamido-2-deoxy-4-(a-L-fucopyranosyl)-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 8-Methoxycarbonyloctyl 2-acetamido-2-deoxy-4-(a-L-fucopyranosyl)-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside, an intriguing biochemical compound extensively employed in the field of biomedicine, exhibits remarkable inhibitory properties against specific enzymes crucial to the biosynthesis of select glycoproteins. With its distinctive structural composition and mechanism of action, this compound presents itself as an auspicious contender for extensive research and development within the biomedical industry. CAS No. 56343-02-3. | |
8R-Brassicasterol Quick inquiry Where to buy Suppliers range | 8R-Brassicasterol is a by-product in the synthesis of Brassicasterol (B676850). Brassicasterol is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C28H46O. US Biological Life Sciences. | Worldwide |
Acetoxyacetic acid Quick inquiry Where to buy Suppliers range | Acetoxyacetic acid (CAS# 13831-30-6) is a versatile organic building block, used in the synthesis of pharmaceutical compounds, including inhibitors and therapeutic agents. It can be used for the synthesis of analogs of 5-Aminolevulinic Acid, which are potential inhibitors of ALA dehydratase (porphobilinogen synthase), an early enzyme of tetrapyrrole biosynthesis. Synonyms: 2-acetyloxyacetic acid. CAS No. 13831-30-6. Molecular formula: C4H6O4. Mole weight: 118.09. | |
ATIC Dimerization Inhibitor (Ac-Arg-Ph(4-NO2)-NEt2, ATIC Inhibitor, AICAR Tfase Inhibitor, AICAR Transformylase Inhibitor, AICAR Tranformylase/Inosine Monophosphate Cyclohydrolase Dimerization Inhibitor, AMPK Signaling Activator XI) Quick inquiry Where to buy Suppliers range | A cell-permeable dipeptide that reversibly blocks the homodimerization of aminoimidazole carboxamide ribonucleotide transformylase/inosine nomophosphate cyclohydrolase (ATIC) and inhibits its activity (Ki = 691nM, Kd = 240nM). AITC is a bifunctional enzyme that catalyzes the last two steps of de novo purine biosynthesis. Increases the intracellular levels of AICAR leading to the activation of AMP-activated protein kinase (AMPK). Shown to reduce cell viability in a dose-dependent manner. Exhibits a longer half-life and sustained AMPK activation (~24h), compared to AICA-riboside. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
Aureobasidin A Quick inquiry Where to buy Suppliers range | Aureobasidin A is an orally available cyclic depsipeptide antibiotic produced by Aureobasidium pullulans that is a fungicide at low concentrations. Aureobasidin A inhibits inositol phosphorylceramide synthase, an enzyme that catalyzes a key step in fungal sphingolipid biosynthesis. This may inhibit fungal cell growth. Uses: Microbial Fermentation Products. CAS No. 127785-64-2. Product ID: MFP-034. | |
BIBB 515 Quick inquiry Where to buy Suppliers range | 2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. BIBB 515 is a selective and potent inhibitor of 2,3-oxidosqualene cyclase (OSC) with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. It is concluded that the lipid-lowering effect of BIBB 515 is mainly the result of an inhibition of LDL production rather than due to an increase in LDL catabolism. OSC inhibitors may offer a novel approach for lipid-lowering therapy. Synonyms: BIBB-515; BIBB515. Grades: ≥98%. CAS No. 156635-05-1. Molecular formula: C22H21ClN2O2. Mole weight: 380.9. | |
Bis(2-aminoethylthio)methane Quick inquiry Where to buy Suppliers range | Bis(2-aminoethylthio)methane is a potential inhibitor of γ-glutamylcysteine synthetase, the first enzyme in the glutathione biosynthesis pathway. Group: Biochemicals. Alternative Names: 2, 2'-[Methylenebis (thio)]bisethanamine. Grades: Highly Purified. CAS No. 22907-27-3. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
Bis(2-aminoethylthio)methane Dihydrochloride Quick inquiry Where to buy Suppliers range | Bis(2-aminoethylthio)methane is a potential inhibitor of γ-glutamylcysteine synthetase, the first enzyme in the glutathione biosynthesis pathway. Group: Biochemicals. Alternative Names: 2, 2'-[Methylenebis (thio)]bisethanamine Dihydrochloride. Grades: Highly Purified. CAS No. 22965-82-8. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
Brassicasterol-(2,2',3,4,4',6-D6) Quick inquiry Where to buy Suppliers range | Brassicasterol-(2,2',3,4,4',6-D6) is derived from Brassicasterol (B676850), which is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H40D6O, Molecular Weight: 404.7. US Biological Life Sciences. | Worldwide |
Brequinar Quick inquiry Where to buy Suppliers range | Brequinar is a synthetic quinolinecarboxylic acid analogue with antineoplastic properties. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby blocking de novo pyrimidine biosynthesis. This agent may also enhance the in vivo antitumor effect of antineoplastic agents such as 5-FU. Check for active clinical trials or closed clinical trials using this agent. Synonyms: DUP785; NSC 368390; 6-Fluoro-2-(2'-fluoro-[1,1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid; 6-fluoro-2-(2'-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-; Biphenquinate. Grades: ≥98%. CAS No. 96187-53-0. Molecular formula: C23H15F2NO2. Mole weight: 375.37. | |
Cellobiose-6'-phosphate Quick inquiry Where to buy Suppliers range | Cellobiose-6'-phosphate, an imperative intermediary in the intricate process of carbohydrate metabolism, manifests as a formidable substrate for an array of enzymes engaged in the biosynthesis of cellulose, a fundamental constituent of plant cell walls. Its remarkable aptitude to elicit cellulose synthesis endows Cellobiose-6'-phosphate with a momentous function in the advancement of anti-fungal medicaments that diligently target cellulose synthesis pathways. Molecular formula: C12H23O14P. Mole weight: 422.28. | |
Cerulenin Quick inquiry Where to buy Suppliers range | Cerulenin is an epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function. It has a role as an antifungal agent, an antiinfective agent, an antilipemic drug, an antimetabolite, a fatty acid synthesis inhibitor and an antimicrobial agent. Uses: Microbial Fermentation Products. CAS No. 17397-89-6. Product ID: MFP-057. | |
Cerulenin (Helicocerin, NSC 116069, 2,3-Epoxy-4-oxo-7,10-dodecadienamide) Quick inquiry Where to buy Suppliers range | Cerulenin is an epoxy fatty acid amide isolated from the fungus Cephalosporium caerulens and identified as an antifungal in the 1960s. Over the past 40 years cerulenin has found broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to B-keto-acyl-ACP synthase blocking the interaction of malonyl CoA. Cerulenin is also an inhibitor of bacterial fatty acid synthesis acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 17397-89-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Cyclopeptine (Benzyl-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione) Quick inquiry Where to buy Suppliers range | Cyclopeptine is a benzodiazepine metabolite produced by a number of species of Penicillium. While there is little literature about the metabolite there is considerable interest in the enzymes responsible for the biosynthesis of the benzodiazepine nucelus, cyclopeptine synthetase. Group: Biochemicals. Alternative Names: Benzyl-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione. Grades: Highly Purified. CAS No. 50886-63-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Cytidine 5'-Triphosphate, 3'-phosphate, 1:1 mixture with Cytidine 5'-Triphosphate, 2'-phosphate Quick inquiry Where to buy Suppliers range | derivatives of Cytidine triphosphate which acts as an inhibitor of the enzyme Aspartate carbamoyltransferase, used in pyrimidine biosynthesis. Molecular formula: C9H17N3O17P4. Mole weight: 563.14. | |
D-Cycloserine dimer Quick inquiry Where to buy Suppliers range | D-Cycloserine dimer is an intermediate in the biosynthesis of S-adenosylmethionine, a cofactor for enzyme-catalyzed methylations. Synonyms: (3R,6R)-3,6-Bis[(aminooxy)methyl]-2,5-piperazinedione; D-3,6-Bis(aminooxymethyl)-2,5-diketopiperazine; D-3,6-Bis(aminoxymethyl)-2,5-dioxopiperazine. Grades: > 95%. CAS No. 16337-02-3. Molecular formula: C6H12N4O4. Mole weight: 204.18. | |
Dehydrocyclopeptine Quick inquiry Where to buy Suppliers range | Dehydrocyclopeptine is a benzodiazepine metabolite produced by a number of species of Penicillium. While there is little literature about the metabolite there is considerable interest in the enzymes responsible for the biosynthesis of the benzodiazepine nucelus, cyclopeptine synthetase. Group: Biochemicals. Grades: Highly Purified. CAS No. 31965-37-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Desmethyl Naftifine HCl Quick inquiry Where to buy Suppliers range | An impurity of Naftifine, which is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,4-epoxidase enzyme. Synonyms: 1-Naphthalenemethanami?ne, N-(3-phenyl-2-propenyl)?-, hydrochloride, (E)?- (9CI). Grades: > 95%. CAS No. 98978-52-0. Molecular formula: C20H19N. HCl. Mole weight: 273.38 36.46. | |
D-Galactose Quick inquiry Where to buy Suppliers range | D-Galactose is an essential monosaccharide product extensively employed in the burgeoning biomedical sector assuming a pivotal position in the intricate biosynthesis of glycoproteins, glycolipids and an assortment of other significant molecules. Not only does it find application in researching metabolic disorders like galactosemia, but it also serves as a substrate for enzymes implicated in the process of galactose catabolism. Synonyms: D-Gal; D-Galactopyranose; D-Galactopyranoside; D-(+)-Galactose. Grades: >98%. CAS No. 59-23-4. Molecular formula: C6H12O6. Mole weight: 180.16. | |
D-Glucose-6-phosphate disodium salt Quick inquiry Where to buy Suppliers range | D-Glucose-6-phosphate disodium salt, a crucial biochemical intermediate involved in glucose metabolism, has multifaceted functions ranging from synthesizing glycogen or generating NADPH for cellular biosynthesis via the pentose phosphate pathway. Its use extends beyond being a mere metabolite to offerings as diverse as being a key component in enzymatic assays to measure glucose-6-phosphate dehydrogenase activity. Furthermore, its central role in metabolic maladies, including type 2 diabetes, cannot be understated. Synonyms: Robison ester disodium salt. CAS No. 3671-99-6. Molecular formula: C6H11Na2O9P. Mole weight: 304.1. | |
(D-Glycero-α-D-manno-heptopyranosyl)-dihydogenphosphate, Cyclohexylammonium Salt Quick inquiry Where to buy Suppliers range | Key intermediate in the metabolism of sugars and their transformation to nucleotides. Also a potential inhibitor for the heptose synthetase, an enzyme of the biosynthesis of the inner core region of lipopolysaccharides. Contains 1-2 equivalents of cyclohexylamine. Synonyms: Cyclohexanamine; [(2R,3S,4S,5S,6R)-6-[(1R)-1,2-dihydroxyethyl]-3,4,5-trihydroxyoxan-2-yl] dihydrogen phosphate; Cyclohexanamine--1-O-phosphono-alpha-D-manno-heptopyranose (1/1); (D-Glycero-?-D-manno-heptopyranosyl)-dihydogenphosphate, Cyclohexylammonium Salt; Cyclohexanamine (2R,3S,4S,5S,6R)-6-((R)-1,2-dihydroxyethyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl phosphate. CAS No. 359435-45-3. Molecular formula: C13H28NO10P. Mole weight: 389.34. | |
D-Ribose-5-phosphate disodium salt hydrate Quick inquiry Where to buy Suppliers range | D-Ribose-5-phosphate disodium salt hydrate is a pivotal biomolecule extensively utilized in the biomedical sector, showcasing remarkable enzymatic attributes while serving as a pivotal participant in nucleotide and nucleic acid biosynthesis. It finds extensive application as a precursor in DNA and RNA synthesis. Synonyms: D-Ribofuranose 5-phosphate disodium salt hydrate. CAS No. 18265-46-8. Molecular formula: C5H9Na2O8P H2O. Mole weight: 274.07. | |
Eflornithine Quick inquiry Where to buy Suppliers range | Eflornithine is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells. Synonyms: Ornithine, 2-(difluoromethyl)-; 2-(Difluoromethyl)ornithine; 2-(Difluoromethyl)-DL-ornithine; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; DFMO; DFMO (growth regulator); Difluromethylornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine. Grades: ≥95%. CAS No. 70052-12-9. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. | |
Eflornithine Hydrochloride Monoydrate Quick inquiry Where to buy Suppliers range | Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism. Group: Biochemicals. Alternative Names: 2-(Difluoromethyl)-DL-ornithine Hydrochloride Hydrate; 2- (Difluoromethyl) ornithine; DFMO; DL-2- (Difluoromethyl) ornithine; DL-α - (Difluoromethyl) ornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α , δ -Diamino-α - (difluoromethyl) valeric Acid; α-(Difluoromethyl)-DL-ornithine; α - (Difluoromethyl) ornithine. Grades: Highly Purified. CAS No. 96020-91-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??ClF?N?O?, Molecular Weight: 236.64. US Biological Life Sciences. | Worldwide |
epi-Kifunensine Quick inquiry Where to buy Suppliers range | epi-Kifunensine is a catalytically potent inhibitor of α-mannosidase I enzyme. By illuminating the multifaceted functions of α-mannosidase I in intricate protein glycosylation pathways, this product emerges as an indispensable tool fostering profound comprehension of glycoprotein biosynthesis. Moreover, its salience extends to study advancements targeting α-mannosidase I dysfunction-driven maladies, notably lysosomal storage disorders. Synonyms: (5R,6R,7S,8R,8aR)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione. Molecular formula: C8H12N2O6. Mole weight: 232.19. | |
Fenhexamid Quick inquiry Where to buy Suppliers range | Fenhexamid is an anti-botrytis fungicide widely used against a broad spectrum of fungi in agricultural crops. Its mode of action involves the inhibition of sterol biosynthesis. Fenhexamid may be used as a standard in the determination of fenhexamid in: Fruits using enzyme-linked immunosorbent assay (ELISA). Tomatoes, grape and wine samples using high-performance liquid chromatography coupled with ultraviolet detector and gas chromatography (GC) coupled with detectors such as nitrogen-phosphorus detector (NPD), electron capture detector (ECD) and ion trap mass spectrometry (ITMS). Group: Biochemicals. Alternative Names: N- (2, 3-Dichloro-4-hydroxyphenyl) -1- methyl cyclohexane carboxamide; Decree; Elevate; KBR 2738; Teldor. CAS No. 126833-17-8. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C??H??Cl?NO?, Molecular Weight: 302.2. US Biological Life Sciences. | Worldwide |
FK-866 Quick inquiry Where to buy Suppliers range | Nampt/visfatin inhibitor. Inhibitor of NAD+ biosynthesis. Inhibits the enzyme/substrate complex and the free enzyme (Ki = 0.4nM and Ki = 0.3nM, respectively). Apoptosis inducer. Autophagy inducer. Causes premature senescence. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 658084-64-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H29N3O2. US Biological Life Sciences. | Worldwide |
Fosmidomycin sodium salt Quick inquiry Where to buy Suppliers range | Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: Antibiotic FR31564; FR31564; P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt. Grades: ≥95%. CAS No. 66508-37-0. Molecular formula: C4H9NO5P.Na. Mole weight: 205.08. | |
FR900098 sodium salt Quick inquiry Where to buy Suppliers range | FR900098 is a derivative of fosmidomycin that displays antimalarial activity. FR900098 is an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: (3-(Acetylhydroxyamino)propyl)-phosphonic acid, monosodium salt; BRN 2096083; P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid, monosodium salt. Grades: ≥95%. CAS No. 73226-73-0. Molecular formula: C5H11NO5P·Na. Mole weight: 219.1. | |
Galeterone Quick inquiry Where to buy Suppliers range | Galeterone (TOK-001 or VN/124-1) is a novel antiandrogen under development by Tokai Pharmaceuticals for the treatment of prostate cancer. It possesses a unique dual mechanism of action, acting as both anandrogen receptor antagonist and an inhibitor of CYP17A1, an enzyme required for the biosynthesis of theandrogens. Synonyms: TOK-001; TOK 001; TOK001; NX41765; NX 41765; NX-41765; VN 124; VN124; VN-124; VN/124-1; (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol. Grades: >98%. CAS No. 851983-85-2. Molecular formula: C26H32N2O. Mole weight: 388.555. | |
Glycinamide ribonucleotide Quick inquiry Where to buy Suppliers range | Glycineamide ribonucleotide (or GAR) is an intermediate in de novo purine biosynthesis. It is formed from phosphoribosylamine by the enzyme phosphoribosylamine-glycine ligase. In the next step of purine biosynthesis the enzyme phosphoribosylglycinamide formyltransferase acts on GAR to form FGAR. GAR formation is stimulated by Luteinizing hormone (LH) and Chorionic gonadotropin (HCG) via activation of Glc-6-P-dehydrogenase. Synonyms: 5'-Phosphoribosylglycinamide; N1-(5-Phospho-D-ribosyl)glycinamide; [(2R,3S,4R,5R)-5-[(2-aminoacetyl)amino]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate; n-glycyl-5-o-phosphono-|A-d-ribofuranosylamine; 5'-phosphoribosylglycinamide; GAR; N1-(5-Phospho-D-ribosyl)glycinamide; N1-(5-phospho-beta-D-ribosyl)glycinamide. CAS No. 10074-18-7. Molecular formula: C7H15N2O8P. Mole weight: 286.18. | |
Guanosine 5'-triphosphate Quick inquiry Where to buy Suppliers range | Guanosine triphosphate (GTP) is a guanine nucleotide containing three phosphate groups esterified to the sugar moiety. GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. Synonyms: D-Guanosine 5'-triphosphate; Guanosine triphosphate; Guanosine 5'-triphosphoric acid; pppG; guanosine 5'-O-(triphosphate); [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Grades: ≥98% by AX-HPLC. CAS No. 86-01-1. Molecular formula: C10H16N5O14P3. Mole weight: 523.18. | |
Hydroxy Terbinafine Quick inquiry Where to buy Suppliers range | A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Inosine-5'-diphosphate Quick inquiry Where to buy Suppliers range | Inosine-5-diphosphate is a nucleoside diphosphate that is indubitably vital to cellular energy metabolism. It serves as a crucial substrate for enzymes involved in purine salvage pathways and contributes to the biosynthesis of purine nucleotides. Additionally, IDP has been linked to an array of signal transduction pathways and has the ability to modulate the activity of ion channels. There is promising potential for IDP to become an effective therapy option for diseases characterized by purine metabolism imbalances. Synonyms: Inosine diphosphate; Riboxin; Inosine 5'-pyrophosphate; IDP; riboxine; Inosine pyrophosphate; Inosine 5'-(trihydrogen diphosphate); 9-{5-O-[Hydroxy(phosphonooxy)phosphoryl]-β-D-ribofuranosyl}-9H-purin-6-ol; 5'-IDP; Inosine 5'-diphosphoric acid. Grades: ≥98% by HPLC. CAS No. 86-04-4. Molecular formula: C10H14N4O11P2. Mole weight: 428.19. | |
L-Aspartic Acid, non-animal Quick inquiry Where to buy Suppliers range | Aspartic acid (abbreviated as Asp or D; encoded by the codons [GAU and GAC]), also known as aspartate, is an α-amino acid that is used in the biosynthesis of proteins.[3] Similar to all other amino acids it contains an amino group and a carboxylic acid. Its α-amino group is in the protonated -NH+3 form under physiological conditions, while its α-carboxylic acid group is deprotonated ?COO? under physiological conditions. Aspartic acid has an acidic side chain (CH2COOH) which reacts with other amino acids, enzymes and proteins in the body. Under physiological conditions (pH 7.4) in proteins the side chain usually occurs as the negatively charged aspartate form, ?COO?. It is a non-essential amino acid in humans, meaning the body can synthesize it as needed.D-Aspartate is one of two D-amino acids commonly found in mammals. In proteins aspartate sidechains are often hydrogen bonded, often as asx turns or asx motifs, which often occur at the N-termini of alpha helices. Asp's L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. Asp (and glutamic acid) is classified as acidic, with a pKa of 3.9, however in a peptide this is highly dependent on the local environment (as with all amino acids), and could be as high as 14. Asp is pervasive in biosynthesis. Group: Biochemicals. Alternative Names: (S)-(+)-Aminosuccinic acid; (S)-Aminobutanedioic acid. Grades: Cell Culture Grade. CAS No. 56-84-8. Pack Sizes: 100g, 500g, 1Kg, 2.5Kg, 10Kg. Molecular Formula: C4H7NO4, Molecular Weight: 133.1. US Biological Life Sciences. | Worldwide |
Liarozole hydrochloride Quick inquiry Where to buy Suppliers range | Liarozole is a benzimidazole derivative with potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits cytochrome P450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, resulting in an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. This agent also inhibits aromatase, the enzyme that catalyzes the final, rate-limiting step in estrogen biosynthesis. Synonyms: Liarozole HCl; R75251 (hydrochloride); 5-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole hydrochloride. CAS No. 145858-50-0. Molecular formula: C17H14Cl2N4. Mole weight: 345.23. | |
Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-α-D-glucopyranoside Quick inquiry Where to buy Suppliers range | A molecule for studying the substrate specificity of certain transferase enzymes involved in glycoprotein biosynthesis, which has also been used to investigate the epitope binding of particular murine monoclonal antibodies. Uses: A molecule for studying the substrate specificity of certain transferase enzymes involved in glycoprotein biosynthesis. it has also been used to investigate the epitope binding of particular murine monoclonal antibodies. Synonyms: Methyl 4-Deoxy-D-xylo-hexopyranoside Tribenzoate; Methyl 4-Deoxy-α-D-xylo-hexopyranoside Tribenzoate. CAS No. 19488-41-6. Molecular formula: C28H26O8. Mole weight: 490.5. | |
Methyl-D-erythritol-d3 Phosphate Quick inquiry Where to buy Suppliers range | A labeled substrate for terpenoid biosynthesis; terpenoid biosynthesis enzyme Escherichia. Group: Biochemicals. Alternative Names: (2S,3R)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
methylwyosine Quick inquiry Where to buy Suppliers range | By inhibiting the activity of Wybutosine biosynthesis, Methylwyosine facilitates targeted therapy for leukemia and lymphomas. Its mechanism of action involves disrupting the function of Wyosine synthase, a crucial enzyme in nucleic acid synthesis, ultimately impeding tumor growth and progression. Synonyms: 9H-Imidazo[1,2-a]purin-9-one, 3,4-dihydro-4,6,7-trimethyl-3-b-D-ribofuranosyl-; 3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine; 4,6,7-Trimethyl-3-pentofuranosyl-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one. CAS No. 108274-04-0. Molecular formula: C15H19N5O5. Mole weight: 349.35. | |
Miglustat Quick inquiry Where to buy Suppliers range | Miglustat is an inhibitor of the ceramide-specific glycosyltransferase, which catalyzes the first step of glycosphingolipid biosynthesis and is currently approved for the oral treatment of type I Gaucher disease (GD1). Uses: Enzyme inhibitors. Synonyms: Zavesca; Miglustat; NB-DNJ. Grades: >98%. CAS No. 72599-27-0. Molecular formula: C10H21NO4. Mole weight: 219.28. | |
MR-566A Quick inquiry Where to buy Suppliers range | It is produced by the strain of Trichoderma harzianus KCTC 0114BP. MR-566A inhibited mushroom enzyminase and melanin biosynthesis in B16 melanoma cells with IC50 (μmol/L) of 1.72 and 0.1, respectively. Synonyms: SCHEMBL20203773. Molecular formula: C8H10ClNO3. Mole weight: 203.62. | |
MR-566B Quick inquiry Where to buy Suppliers range | It is produced by the strain of Trichoderma harzianus KCTC 0114BP. MR-566B inhibited mushroom enzyminase and melanin biosynthesis in B16 melanoma cells with IC50 (μmol/L) of 47 and 2.2, respectively. Synonyms: SCHEMBL20203767. Molecular formula: C8H11NO4. Mole weight: 185.18. | |
Myriocin (Thermozymocidin, ISP) Quick inquiry Where to buy Suppliers range | Myriocin is an a-amino fatty acid derived from species of several genera of fungi, notably Myriococcum, Melanconis and Isaria. Myriocin is a potent inhibitor of sphingosine biosynthesis by blocking the first enzyme in the pathway, serine palmitoyltransferase. Myriocin induces apoptosis by depletion of cellular sphingolipids, inhibits proliferation of IL-2-dependent mouse cytotoxic cells and is a potent immunosuppressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 35891-70-4. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
N-Acetylmuramic acid methyl ester Quick inquiry Where to buy Suppliers range | N-Acetylmuramic acid methyl ester, an indispensable constituent in bacterial peptidoglycan synthesis, plays a vital role as a substrate for transpeptidase enzymes that participate in bacterial cell division. This compound is extensively employed in antibiotic-related investigations, encompassing penicillins, cephalosporins, and studies pertaining to bacterial cell wall biosynthesis. Synonyms: 2-Acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucose methyl ester. CAS No. 99689-20-0. Molecular formula: C12H21NO8. Mole weight: 307.30. | |
Naftifine Quick inquiry Where to buy Suppliers range | Naftifine is a topical, synthetic, broad spectrum allylamine derivate. It has antifungal, antibacterial and anti-inflammatory activity and is used for the treatment of tinea pedis, tinea cruris, and tinea corporis. It can be fungicidal or fungistatic depending on the concentration and the organisms involved. It appears to interfere with sterol biosynthesis by inhibiting the enzyme squalene 2,3-epoxidase. It was developed by Merz pharma and has been listed. Uses: Naftifine has antifungal, antibacterial and anti-inflammatory activity and is used for the treatment of tinea pedis, tinea cruris, and tinea corporis. Synonyms: Naftifinum; AW105843; AW-105843; SN105843; SN-105843; N-trans-cinnamyl-n-methyl-(1-naphthylmethyl)amine. Grades: 98%. CAS No. 65472-88-0. Molecular formula: C21H21N. Mole weight: 287.41. | |
Naftifine cis-Isomer Quick inquiry Where to buy Suppliers range | An impurity of Naftifine, which is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,5-epoxidase enzyme. Synonyms: (Z)-N-Methyl-N-(3-phenyl-2-propen-1-yl)-1-naphthalenemethanamine Hydrochloride;(Z)-N-Cinnamyl-N-methyl-1-naphthalenemethanamine Hydrochloride. Grades: > 95%. CAS No. 65473-08-7. Molecular formula: C21H21N. Mole weight: 287.41. | |
Naftifine Impurity 1 Quick inquiry Where to buy Suppliers range | An impurity of Naftifine, which is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme. Synonyms: 1-(4-(Aminomethyl)naphthalen-1-yl)-N,N-dimethylmethanamine. Grades: > 95%. Molecular formula: C14H18N2. Mole weight: 214.31. | |
Nα-Boc-L-ornithine Quick inquiry Where to buy Suppliers range | Nα-Boc-L-Ornithine, is a boc-protected analogue of L-Orthinine, a non-essential amino acid and intermediate in arginine biosynthesis. It can be used in the enzymatic preparation of N-BOC-5-hydroxy-L-proline, and N-Cbz-5-hydroxy-L-proline, which are alternative key intermediates for the synthesis of Saxagliptin, used for the treatment of type II diabetes mellitus. Synonyms: Boc-L-Orn-OH; (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid; Boc-Orn-OH; L-5-Amino-2-tert-butoxycarbonylamino-pentanoicacid; Boc-L-ornithine; Nalpha-Boc-L-ornithine; N2-Boc-L-ornithine. Grades: ≥ 99% (HPLC). CAS No. 21887-64-9. Molecular formula: C10H20N2O4. Mole weight: 232.30. | |
Nitisinone Quick inquiry Where to buy Suppliers range | Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I. Group: Biochemicals. Alternative Names: 2-[2-Nitro-4- (trifluoromethyl) benzoyl]-. Grades: Highly Purified. CAS No. 104206-65-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Nitisinone-13C6 Quick inquiry Where to buy Suppliers range | Labeled Nitisinone. Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I. Group: Biochemicals. Alternative Names: 2-[2-Nitro-4- (trifluoromethyl) benzoyl]-. Grades: Highly Purified. CAS No. 1246815-63-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
PBTZ169 Quick inquiry Where to buy Suppliers range | PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. DprE1 is an essential enzyme involved in the cell wall biosynthesis of Corynebacterineae. The MIC values of PBTZ169 ranged from 0.03 μg/mL to 0.0037 μg/mL. The MIC50 value of PBTZ169 was 0.0075μg/mL; MIC90 value was 0.030 μg/mL. Uses: Anti-bacterial. Synonyms: PBTZ169; PBTZ-169; PBTZ 169; macozinone; 2-(4-(cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one. Grades: 98%. CAS No. 1377239-83-2. Molecular formula: C20H23F3N4O3S. Mole weight: 456.48. | |
PKM2 Activator III (N- (4- (4- (2-Methoxyphenyl) piperazine-1-carbonyl) phenyl) quinoline-8-sulfonamide, Pyruvate Kinase M2 Activator III) Quick inquiry Where to buy Suppliers range | A cell-permeable quinoline-sulfonamide that acts as a potent allosteric PKM2 activator both in cell-free enzymatic assays (AC50 = 17nM with 40ng PKM2/200ul) and in cultures (AC50 = 45nM in A549 cells) via a high affinity, 2:1 stoichiometric binding, effectively locking PKM2 in an active tetrameric state resistant to known intracellular negative regulators of FBP-activated PKM2 tetramer. PKM2 stimulation by compound treatment is shown to result in decreased serine biosynthesis (by 56%; 500nM for 24h) with concomitant increase in serine influx as a compensating mechanism for maintaining cellular serine level necessary for supporting A549 proliferation. Simultaneous PKM2 activation and culture serine withdrawal results in cytostatic A549 growth arrest, but not apoptosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Polyporic acid Quick inquiry Where to buy Suppliers range | Polyporic acid is an intermediate in the biosynthesis of allantofuranone first isolated from a mycelial culture of the fungus species Hapalopilus nidulans. It inhibits the enzyme dihydroorotate dehydrogenase and has some antifungal and antibacterial activity. Synonyms: 3',6'-dihydroxy-[1,1':4',1''-terphenyl]-2',5'-dione; Orygameic acid; 2,5-Dihydroxy-3,6-diphenyl-p-benzoquinone; NSC 44175; 2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3,6-diphenyl-. Grades: ≥95%. CAS No. 548-59-4. Molecular formula: C18H12O4. Mole weight: 292.29. | |
(R,R)-Hymeglusin Quick inquiry Where to buy Suppliers range | beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. Group: Biochemicals. Alternative Names: 1233A, F-244, L-659-699. Grades: Highly Purified. CAS No. 29066-42-0. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |