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[1,1'-Biphenyl]-2-carboxamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [1,1'-biphenyl]-2-carboxamide;Einecs 236-206-4. Product Category: Heterocyclic Organic Compound. CAS No. 13234-79-2. Molecular formula: C13H11NO. Mole weight: 197.23254. Product ID: ACM13234792. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-Phenylbenzamide.
1-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 748812-53-5. IUPAC Name: 1-(pentanoylamino)-N-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]cyclopentane-1-carboxamide. Molecular formula: C25H30N6O2. Mole weight: 446.54. Catalog: APS748812535. SMILES: CCCCC(=O)NC1(CCCC1)C(=O)NCc2ccc(cc2)c3ccccc3c4nnn[nH]4. Format: Neat.
4'-(Azidomethyl)-[1,1'-biphenyl]-2-carboxamide
One of the impurities of Telmisartan, which is an angiotensin II receptor antagonist and could be used in the treatment of hypertensive. Synonyms: Telmisartan Impurity 14; Olmesartan Impurity 16; 4'-(Azidomethyl)[1,1'-biphenyl]-2-carboxamide; 4'-(Azidomethyl)biphenyl-2-carboxamide; Irbesartan Impurity 24. Grade: ≥95%. CAS No. 2763750-28-1. Molecular formula: C14H12N4O. Mole weight: 252.28.
4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide
4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 147404-72-6. IUPAC Name: 2-[4-(bromomethyl)phenyl]benzamide. Molecular formula: C14H12BrNO. Mole weight: 290.16. Catalog: APS147404726. SMILES: NC(=O)c1ccccc1c2ccc(CBr)cc2. Format: Neat.
A cell-permeable acylguanidine compound that is shown to block Hh signaling and act as a potent, reversible and high-affinity Smo (Smoothened) antagonist. Displays 20-60 -fold greater potency than Cyclopamine and competitively inhibits bodipy-cyclopamine binding to Smo (IC50 = 4.6 and 14nM in HEK293-hSMO and HEK293-mSMO cells, respectively). Represses ShhN (N-myristoylated Shh) signaling (IC50=15nM for Gli-dependent luciferase activity in Shh-light2 cells) and SAG- induced C3H10T1/2 cell differentiation (IC50=10nM in an alkaline phosphatase activity assay). Inhibits ShhN (3nM) and SAG (10nM)-mediated proliferation of rat cerebellar granule cell precursors (IC50 ~3 and 6nM, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
A GABAA receptor modulator that effects against anxiety. Synonyms: 3'-(5-(2-Hydroxypropan-2-yl)-1H-benzo[d]imidazol-1-yl)-[1,1'-biphenyl]-2-carboxamide; GABAA Modulator I; SCHEMBL1761811; MFCD30186081; AKOS027439948; ZINC117027649. CAS No. 951654-29-8. Molecular formula: C23H21N3O2. Mole weight: 371.44.
2-Phenylbenzamide
2-Phenylbenzamide. Group: Biochemicals. Alternative Names: 1,1'-Biphenyl]-2-carboxamide; 2-Biphenylcarboxamide. Grades: Highly Purified. CAS No. 13234-79-2. Pack Sizes: 1g. Molecular Formula: C13H11NO, Molecular Weight: 197.23. US Biological Life Sciences.
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3-Bromo-2-methoxybenzoic Acid
3-Bromo-2-methoxybenzoic Acid is a reactant that has been used in the preparation of biphenylic carboxamides as potent and selective CB2 receptor ligands. Group: Biochemicals. Grades: Highly Purified. CAS No. 101084-39-3. Pack Sizes: 1g, 5g. Molecular Formula: C8H7BrO3, Molecular Weight: 231.04. US Biological Life Sciences.
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Antibacterial agent 67
Antibacterial agent 67 (IC50 = 0.03 μM) has a great enzyme-inhibiting activity on succinate dehydrogenase than fluxapyroxad (IC50 = 4.40 μM). Synonyms: 3-(difluoromethyl)-N-(4'-((2,6-difluorophenyl)diazenyl)-3',5'-difluoro-[1,1'-biphenyl]-2-yl)-1-methyl-1H-pyrazole-4-carboxamide. CAS No. 2488900-01-0. Molecular formula: C24H15F6N5O. Mole weight: 503.40.
ARCC-4
ARCC-4 is a PROTAC, acting as an androgen receptor degrader. ARCC-4 is a low-nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. It inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Synonyms: ARCC-4; 1973403-00-7; (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CHEMBL4540528; SCHEMBL17946930; DUPAJELXESPTNF-PPZGWQTASA-N; AKOS040741162; MS-31874; HY-130492; CS-0108331; EN300-7526556; Z3482428589; O1-(ABM-14 ether), O4-(Methylcarboxamide with AHPC) Butanediol; (2S,4R)-1-[(2S)-2-(2-{4-[(4'-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-[1,1'-biphenyl]-4-yl)oxy]butoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide. Grade: 99%. CAS No. 1973403-00-7. Molecular formula: C53H56F3N7O7S2. Mole weight: 1024.18.
AVE-0118
AVE 0118 is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to the anti-AF property of AVE0118. Synonyms: [1,1'-Biphenyl]-2-carboxamide, 2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; AVE 0118; AVE0118. Grade: ≥95%. CAS No. 498577-53-0. Molecular formula: C30H29N3O3. Mole weight: 479.57.
AVE 0118 hydrochloride
AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Synonyms: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grade: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03.
Compound 43 TAO Kinase Inhibitor
Compound 43 TAO kinase inhibitor is an ATP-competitive and selective inhibitor of TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Synonyms: N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide. Grade: ≥98%. CAS No. 850467-66-2. Molecular formula: C25H24N2O2. Mole weight: 384.47.
Conivaptan
Conivaptan, also called as YM 087 or Vaprisol, is the first is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) approved by United States Federal Drug Administrations (FDA) for the treatment of hyponatremia. Synonyms: [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-; N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl][1,1'-biphenyl]-2-carboxamide; ZINC 12503187; N-(4-(2-methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. Grade: 95%. CAS No. 210101-16-9. Molecular formula: C32H26N4O2. Mole weight: 498.58.
Conivaptan
Conivaptan. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CONIVAPTAN;N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1-biphenyl]-2-carboxamide. Product Category: Heterocyclic Organic Compound. CAS No. 210101-16-9. Molecular formula: C32H26N4O2. Mole weight: 498.583. Product ID: ACM210101169. Alfa Chemistry ISO 9001:2015 Certified.
Conivaptan hydrochloride
Conivaptan HCl is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist). Uses: Antidiuretic hormone receptor antagonists. Synonyms: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087; [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1); [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride; Conivaptan monohydrochloride. Grade: >98%. CAS No. 168626-94-6. Molecular formula: C32H26N4O2.HCl. Mole weight: 535.04.
Used in treatment of congestive heart failure. Group: Biochemicals. Alternative Names: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087. Grades: Highly Purified. CAS No. 168626-94-6. Pack Sizes: 25mg. US Biological Life Sciences.
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Conivaptan impurity G
Conivaptan impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(4-(2-methyl-5,6-dihydro-4Hbenzo[b]oxazolo[5,4-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. CAS No. 168626-93-5. Molecular formula: C32H25N3O3. Mole weight: 499.56. Catalog: APB168626935.
CP 346086
CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grade: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48.
CP 346086 Dihydrate
CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor for treatment of obesity. Group: Biochemicals. Alternative Names: N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide Dihydrate. Grades: Highly Purified. CAS No. 186390-48-7. Pack Sizes: 10mg. US Biological Life Sciences.
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DHODH-IN-14
DHODH-IN-14, a hydroxyfurazan analogue of A771726, is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 0.49 μM for rat liver DHODH. It can be used for rheumatoid arthritis. Synonyms: 4-Oxo-N-(2,3,5,6-tetrafluoro-4-biphenylyl)-4,5-dihydro-1,2,5-oxadiazole-3-carboxamide; 1,2,5-Oxadiazole-3-carboxamide, 4,5-dihydro-4-oxo-N-(2,3,5,6-tetrafluoro[1,1'-biphenyl]-4-yl)-. Grade: ≥95%. CAS No. 1364791-93-4. Molecular formula: C15H7F4N3O3. Mole weight: 353.23.
DHODH-IN-15
DHODH-IN-15, a hydroxyfurazan analogue of A771726, is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 11 μM for rat liver DHODH. It can be used for rheumatoid arthritis. Synonyms: N-(4-Biphenylyl)-4-oxo-4,5-dihydro-1,2,5-oxadiazole-3-carboxamide; 1,2,5-Oxadiazole-3-carboxamide, N-[1,1'-biphenyl]-4-yl-4,5-dihydro-4-oxo-. Grade: ≥95%. CAS No. 1364791-88-7. Molecular formula: C15H11N3O3. Mole weight: 281.27.
DPC 423
DPC 423. Group: Biochemicals. Alternative Names: 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide hydrochloride; 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide monohydrochloride. Grades: Highly Purified. CAS No. 292135-59-2. Pack Sizes: 10mg. Molecular Formula: C25H21ClF4N4O3S. US Biological Life Sciences.
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DT-2216
DT2216 is a potent and selective Bcl-xL-specific degrader. DT2216 is highly active against Bcl-xL-dependent T cell lymphomas. DT2216 selectively killed various Bcl-xL-dependent TCL cells including MyLa cells in vitro. In vivo, DT2216 alone was highly effective against MyLa TCL xenografts in mice without causing significant thrombocytopenia or other toxicity. Furthermore, DT2216 combined with ABT199 (a selective Bcl-2 inhibitor) synergistically reduced disease burden and improved survival in a TCL PDX mouse model dependent on both Bcl-2 and Bcl-xL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DT-2216; DT2216; DT 2216; DT2216 HCl. Product Category: Others. Appearance: Solid powder. CAS No. 2365172-42-3. Molecular formula: C77H96ClF3N10O10S4. Mole weight: 1542.36. Purity: >98%. IUPACName: (2S,4R)-1-((S)-2-(7-(4-((R)-3-((4-(N-(4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide. Canonical SMILES: CC1(C)CCC(C2=CC=C(Cl)C=C2)=C(C1)CN3CCN(C4=CC=C(C(NS(=O)(C5=CC(S(C(F)(F)F)(=O)=O)=C(N[C@@H](CSC6=CC=CC=C6)CCN7CCN(C(CCCCCC(N[C@@H](C(C)(C)C)C(N8[C@@H](C[C@@H](O)C8)C(N[C@H](C9=CC=C(C%10=C(N=CS%10)C)C=C9)C)=O)=O)=O)=O)CC7)C=C5)=O)=O)C=C4)
DUN99845
DUN99845 is a a lifespan-altering agent. DUN99845 was first reported in patent US 20090163545. DUN99845 was also reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DUN99845; DUN-99845; DUN 99845. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 727699-84-5. Molecular formula: C26H21FN2O4S. Mole weight: 476.52. Purity: >98%. IUPACName: N-[3-[[(4-Fluorophenyl)sulfonyl]amino]-4-methoxyphenyl][1,1'-biphenyl]-4-carboxamide. Canonical SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC3=CC=C(OC)C(NS(=O)(C4=CC=C(F)C=C4)=O)=C3. Product ID: ACM727699845. Alfa Chemistry ISO 9001:2015 Certified.
Eltrombopag Amide
Eltrombopag Amide. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H23N5O3, Molecular Weight: 441.48. US Biological Life Sciences.
Worldwide
Eltrombopag Amide
Eltrombopag Amide is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grade: > 95%. CAS No. 1246929-02-1. Molecular formula: C25H23N5O3. Mole weight: 441.48.
Eltrombopag Impurity 5
Eltrombopag Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxamide. CAS No. 1246929-02-1. Molecular formula: C25H23N5O3. Mole weight: 441.48. Catalog: APB1246929021.
Erismodegib
Erismodegib. Group: Biochemicals. Alternative Names: rel-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-1,1'-biphenyl]-3-carboxamide; LDE 225; NVP-LDE 225. Grades: Highly Purified. CAS No. 956697-53-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C26H26F3N3O3. US Biological Life Sciences.
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GMC 15-27
GMC 15-27 is a selective 5-HT1B/1D antagonist. Synonyms: 4'-(Aminoiminomethyl)-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-[1,1'-biphenyl]-4-carboxamide. Grade: 98%. CAS No. 256227-71-1. Molecular formula: C27H31N5O2. Mole weight: 457.57.
GR 103691
GR 103691 is a potent dopamine D3 receptor antagonist. Uses: Dopamine antagonists. Synonyms: GR 103691; GR103691; GR-103691; 4'-Acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide. Grade: 99%. CAS No. 162408-66-4. Molecular formula: C30H35N3O3. Mole weight: 485.62.
GR 127935
GR 127935 is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting >100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Uses: Serotonin antagonists. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide; GR127935; GR-127935. Grade: ≥95%. CAS No. 148672-13-3. Molecular formula: C29H31N5O3. Mole weight: 497.59.
GR 127935 hydrochloride
GR 127935 hydrochloride is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrochloride (1:1); [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, monohydrochloride; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide hydrochloride; GR127935 hydrochloride; GR-127935 hydrochloride. Grade: ≥99% by HPLC. CAS No. 148642-42-6. Molecular formula: C29H31N5O3.HCl. Mole weight: 534.06.
Grp94 Inhibitor-1
Grp94 Inhibitor-1 is a potent and selective inhibitor of Grp94 (IC50 = 2 nM), and over 1000-fold selectivity to Grp94 against Hsp90α. Synonyms: [1,1'-Biphenyl]-3-carboxamide, 4-[(trans-4-hydroxycyclohexyl)amino]-4'-(1-methylethyl)-; 4-[(trans-4-Hydroxycyclohexyl)amino]-4'-isopropyl-3-biphenylcarboxamide; rel-4-(((1R,4R)-4-hydroxycyclohexyl)amino)-4'-isopropyl-[1,1'-biphenyl]-3-carboxamide. Grade: ≥98%. CAS No. 2234897-35-7. Molecular formula: C22H28N2O2. Mole weight: 352.47.
GUN35901
GUN35901 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. GUN35901 is a demethyl analogue of DUN99845 (CAT#556012). GUN35901 was first reported in patent CN 112057443. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GUN35901; GUN-35901; GUN 35901; SN-011; SN011; SN 011. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2249435-90-1. Molecular formula: C25H19FN2O4S. Mole weight: 462.5. Purity: >98%. IUPACName: N-(3-((4-fluorophenyl)sulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide. Product ID: ACM2249435901. Alfa Chemistry ISO 9001:2015 Certified.
Lomitapide
Lomitapide. Group: Biochemicals. Alternative Names: N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide; AEGR 733; BMS 201038; BMS 201038-01; BMS 201238. Grades: Highly Purified. CAS No. 182431-12-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C39H37F6N3O2, Molecular Weight: 693.72. US Biological Life Sciences.
Worldwide
Telmisartan EP Impurity F
One of the impurities of Telmisartan, which is an angiotensin II receptor antagonist and could be used in the treatment of hypertensive. Synonyms: Telmisartan Amide; 4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxamide. Grade: > 95%. CAS No. 915124-86-6. Molecular formula: C33H31N5O. Mole weight: 513.65.
Vat Yellow 10
Vat Yellow 10. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Vat Yellow 10;4',4'''-Azobis[N-[5-(benzoylamino)-9,10-dihydro-9,10-dioxo-1-anthryl][1,1'-biphenyl-4-carboxamide];c.i. 65430;4',4'''-Azobis[N-[5-(benzoylamino)-9,10-dihydro-9,10-dioxoanthracen-1-yl]-1,1'-biphenyl-4-carboxamide];C.I.Vat Yellow 10;Fenanthre. Product Category: Vat Dyes. CAS No. 2379-76-2. Molecular formula: C68H42N6O8. Mole weight: 1071.11. Purity: 0.96. IUPACName: 4,4-Azobis(N-(5-(benzoylamino)-9,10-dihydro-9,10-dioxo-1-anthryl)(. Density: 1.36. Product ID: ACM2379762. Alfa Chemistry ISO 9001:2015 Certified.
Vat Yellow 33
Vat Yellow 33. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4',4'''-azobis[n-(9,10-dihydro-9,10-dioxo-1-anthryl)]-[1,1'-biphenyl]-4-carboxamide;C.I. 65429;vat yellow 33;Vat yellow 33 (C.I. 65429);[1,1'-Biphenyl]-4-carboxamide, 4',4'''-azobis[N-(9,10-dihydro- 9,10-dioxo-1-anthracenyl)-;Yellow F3GC;Cibanone Yellow. Product Category: Vat Dyes. CAS No. 12227-50-8. Molecular formula: C54H32N4O6. Mole weight: 832.86. Purity: 0.96. IUPACName: N-(9,10-dioxoanthracen-1-yl)-4-[4-[[4-[4-[(9,10-dioxoanthracen-1-yl)ca. Density: 1.35. Product ID: ACM12227508. Alfa Chemistry ISO 9001:2015 Certified. Categories: (1,1'-Biphenyl)-4-carboxamide.
GLP-1 receptor agonist 4, a glucagon-like peptide-1 receptor (GLP-1R) agonist with an EC50 of 64.5 nM, can be used in the study of diabetes treatment. (Extracted from patent WO2009111700A2, compound 87). Synonyms: (S)-3-(4'-Cyano-[1,1'-biphenyl]-4-yl)-2-((3R,8S)-3-(4-((3,4-dichlorobenzyl)oxy)phenyl)-1-methyl-2-oxo-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-1H-[1,4]oxazino[3,2-g]isoquinoline-8-carboxamido)propanoic acid; (2S)-3-(4'-Cyano-4-biphenylyl)-2-[({(3R,8S)-3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}-1-methyl-2-oxo-7-[(1S)-1-phenylpropyl]-2,3,6,7,8,9-hexahydro-1H-[1,4]oxazino[3,2-g]isoquinolin-8-yl}carbonyl)amino]propanoic acid. Grade: ≥95%. CAS No. 1187061-62-6. Molecular formula: C51H44Cl2N4O6. Mole weight: 879.82.
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