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| Product | Description | |
|---|---|---|
| 1- [ (1-Oxopentyl) amino] -N- [ [2'- (2H-tetrazol-5-yl) [1, 1'-biphenyl] -4-yl] methyl ] -cyclopentane carboxamide | 1- [ (1-Oxopentyl) amino] -N- [ [2'- (2H-tetrazol-5-yl) [1, 1'-biphenyl] -4-yl] methyl ] -cyclopentane carboxamide (Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite) is a metabolite of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 748812-53-5. Pack Sizes: 5mg, 50mg. Molecular Formula: C25H30N6O2, Molecular Weight: 446.54. US Biological Life Sciences. |  Worldwide |
| 1-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide | 1-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 748812-53-5. IUPAC Name: 1-(pentanoylamino)-N-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]cyclopentane-1-carboxamide. Molecular Formula: C25H30N6O2. Mole Weight: 446.54. Catalog: APS748812535. SMILES: CCCCC (=O)NC1 (CCCC1)C (=O)NCc2ccc (cc2)c3ccccc3c4nnn[nH]4. Format: Neat. |  |
| 4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide | 4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 147404-72-6. IUPAC Name: 2-[4-(bromomethyl)phenyl]benzamide. Molecular Formula: C14H12BrNO. Mole Weight: 290.16. Catalog: APS147404726. SMILES: NC(=O)c1ccccc1c2ccc(CBr)cc2. Format: Neat. | |
| Hh Signaling Antagonist XII, MRT-83 (N- (2-Methyl-5- (3- (3, 4, 5-trimethoxybenzoyl) guanidino) phenyl) - (1, 1-biphenyl) -4-carboxamide) | A cell-permeable acylguanidine compound that is shown to block Hh signaling and act as a potent, reversible and high-affinity Smo (Smoothened) antagonist. Displays 20-60 -fold greater potency than Cyclopamine and competitively inhibits bodipy-cyclopamine binding to Smo (IC50 = 4.6 and 14nM in HEK293-hSMO and HEK293-mSMO cells, respectively). Represses ShhN (N-myristoylated Shh) signaling (IC50=15nM for Gli-dependent luciferase activity in Shh-light2 cells) and SAG- induced C3H10T1/2 cell differentiation (IC50=10nM in an alkaline phosphatase activity assay). Inhibits ShhN (3nM) and SAG (10nM)-mediated proliferation of rat cerebellar granule cell precursors (IC50 ~3 and 6nM, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 2-{3-[5-(2-Hydroxypropan-2-yl)-1H-1,3-benzodiazol-1-yl]phenyl}benzamide | A GABAA receptor modulator that effects against anxiety. Synonyms: 3'-(5-(2-Hydroxypropan-2-yl)-1H-benzo[d]imidazol-1-yl)-[1,1'-biphenyl]-2-carboxamide; GABAA Modulator I; SCHEMBL1761811; MFCD30186081; AKOS027439948; ZINC117027649. CAS No. 951654-29-8. Molecular formula: C23H21N3O2. Mole weight: 371.44. |  |
| 2-Dicyclohexyl(2', 6'-dimethoxybiphenyl)phosphine gold(I) bis(trifluoromethylsulfonyl)imide | Catalyst used in the selective hydration of substituted alkynes at room temperatures. Catalyst used in the hydroarylating/aromatization of arene-diynes. Highly-efficient and regio-selective catalyst for the selective carbonyl migration in alkynyl-substituted indole-3-carboxamides. Intermolecular gold(I) catalyzed alkyne carboalkoxylation reactions for the multicomponent assembly of β-alkoxy ketones. Gold(I)-catalyzed hydration of alkynylphosphonates: Efficient access to β-ketophosphonates. Gold-catalyzed intramolecular hydroamination reaction. Group: Gold catalysts. Alternative Names: MFCD21608485; 1121960-90-4; Bis(trifluoromethanesulfonyl)imide(2-dicyclohexylphosphino-2', 6'-dimethoxy-1, 1'-biphenyl)gold(I). CAS No. 1121960-90-4. Molecular formula: C28H36AuF6NO6PS2+. Mole weight: 888.648g/mol. IUPACName: bis(trifluoromethylsulfonyl)azanide; dicyclohexyl-[2-(2, 6-dimethoxyphenyl)phenyl]phosphanium; gold(1+). Canonical SMILES: COC1=C (C (=CC=C1)OC)C2=CC=CC=C2[PH+] (C3CCCCC3)C4CCCCC4. C (F) (F) (F)S (=O) (=O)[N-]S (=O) (=O)C (F) (F)F. [Au+]. Catalog: ACM1121960904. |  |
| 2-Phenylbenzamide | 2-Phenylbenzamide. Group: Biochemicals. Alternative Names: 1,1'-Biphenyl]-2-carboxamide; 2-Biphenylcarboxamide. Grades: Highly Purified. CAS No. 13234-79-2. Pack Sizes: 1g. Molecular Formula: C13H11NO, Molecular Weight: 197.23. US Biological Life Sciences. | Worldwide |
| 3-Bromo-2-methoxybenzoic Acid | 3-Bromo-2-methoxybenzoic Acid is a reactant that has been used in the preparation of biphenylic carboxamides as potent and selective CB2 receptor ligands. Group: Biochemicals. Grades: Highly Purified. CAS No. 101084-39-3. Pack Sizes: 1g, 5g. Molecular Formula: C8H7BrO3, Molecular Weight: 231.04. US Biological Life Sciences. | Worldwide |
| ARCC-4 | ARCC-4 is a PROTAC, acting as an androgen receptor degrader. ARCC-4 is a low-nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. It inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Synonyms: ARCC-4; 1973403-00-7; (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CHEMBL4540528; SCHEMBL17946930; DUPAJELXESPTNF-PPZGWQTASA-N; AKOS040741162; MS-31874; HY-130492; CS-0108331; EN300-7526556; Z3482428589; O1-(ABM-14 ether), O4-(Methylcarboxamide with AHPC) Butanediol; (2S,4R)-1-[(2S)-2-(2-{4-[(4'-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-[1,1'-biphenyl]-4-yl)oxy]butoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide. Grades: 99%. CAS No. 1973403-00-7. Molecular formula: C53H56F3N7O7S2. Mole weight: 1024.18. | |
| AVE-0118 | AVE 0118 is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to the anti-AF property of AVE0118. Synonyms: [1,1'-Biphenyl]-2-carboxamide, 2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[2- (4-Methoxyphenyl) acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; AVE 0118; AVE0118. Grades: ≥95%. CAS No. 498577-53-0. Molecular formula: C30H29N3O3. Mole weight: 479.57. | |
| AVE 0118 hydrochloride | AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Synonyms: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2- (4-Methoxyphenyl) acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grades: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03. | |
| Chloro[2-dicyclohexyl(2', 6'-dimethoxybiphenyl)phosphine] gold(I) | Highly-efficient and regio-selective catalyst for the selective carbonyl migration in alkynyl-substituted indole-3-carboxamides. Catalyst used in the hydroarylation/aromatization of arene-diynes. Catalyst used in the selective hydration of substituted alkynes at room temperatures. Group: Gold catalysts. Alternative Names: MFCD21608486;Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)gold(I);854045-95-7. CAS No. 854045-95-7. Molecular formula: C26H36AuClO2P+. Mole weight: 643.962g/mol. IUPACName: chlorogold;dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphanium. Canonical SMILES: COC1=C (C (=CC=C1)OC)C2=CC=CC=C2[PH+] (C3CCCCC3)C4CCCCC4. Cl[Au]. Catalog: ACM854045957. | |
| Compound 43 TAO Kinase Inhibitor | Compound 43 TAO kinase inhibitor is an ATP-competitive and selective inhibitor of TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Synonyms: N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide. Grades: ≥98%. CAS No. 850467-66-2. Molecular formula: C25H24N2O2. Mole weight: 384.47. | |
| Conivaptan | Conivaptan, also called as YM 087 or Vaprisol, is the first is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) approved by United States Federal Drug Administrations (FDA) for the treatment of hyponatremia. Synonyms: [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-; N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl][1,1'-biphenyl]-2-carboxamide; ZINC 12503187; N-(4-(2-methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. Grades: 95%. CAS No. 210101-16-9. Molecular formula: C32H26N4O2. Mole weight: 498.58. | |
| Conivaptan Hydrochloride | Conivaptan HCl is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist). Uses: Antidiuretic hormone receptor antagonists. Synonyms: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087; [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1); [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride; Conivaptan monohydrochloride. Grades: >98%. CAS No. 168626-94-6. Molecular formula: C32H26N4O2.HCl. Mole weight: 535.04. | |
| Conivaptan Hydrochloride | Used in treatment of congestive heart failure. Group: Biochemicals. Alternative Names: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087. Grades: Highly Purified. CAS No. 168626-94-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Conivaptan impurity F | Conivaptan impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(4-(2-methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-1-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. Molecular Formula: C32H26N4O2. Mole Weight: 498.57. Catalog: APB04194. | |
| Conivaptan impurity G | Conivaptan impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(4-(2-methyl-5,6-dihydro-4Hbenzo[b]oxazolo[5,4-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. CAS No. 168626-93-5. Molecular Formula: C32H25N3O3. Mole Weight: 499.56. Catalog: APB168626935. | |
| CP 346086 | CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grades: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48. | |
| CP 346086 Dihydrate | CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor for treatment of obesity. Group: Biochemicals. Alternative Names: N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide Dihydrate. Grades: Highly Purified. CAS No. 186390-48-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| DPC 423 | DPC 423. Group: Biochemicals. Alternative Names: 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide hydrochloride; 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide monohydrochloride. Grades: Highly Purified. CAS No. 292135-59-2. Pack Sizes: 10mg. Molecular Formula: C25H21ClF4N4O3S. US Biological Life Sciences. | Worldwide |
| DT-2216 | DT2216 is a potent and selective Bcl-xL-specific degrader. DT2216 is highly active against Bcl-xL-dependent T cell lymphomas. DT2216 selectively killed various Bcl-xL-dependent TCL cells including MyLa cells in vitro. In vivo, DT2216 alone was highly effective against MyLa TCL xenografts in mice without causing significant thrombocytopenia or other toxicity. Furthermore, DT2216 combined with ABT199 (a selective Bcl-2 inhibitor) synergistically reduced disease burden and improved survival in a TCL PDX mouse model dependent on both Bcl-2 and Bcl-xL. Group: Others. Alternative Names: DT-2216; DT2216; DT 2216; DT2216 HCl. CAS No. 2365172-42-3. Molecular formula: C77H96ClF3N10O10S4. Mole weight: 1542.36. Appearance: Solid powder. Purity: >98%. IUPACName: (2S, 4R) -1- ( (S) -2- (7- (4- ( (R) -3- ( (4- (N- (4- (4- ( (4'-chloro-4, 4-dimethyl-3, 4, 5, 6-tetrahydro-[1, 1'-biphenyl]-2-yl) methyl) piperazin-1-yl) benzoyl) sulfamoyl) -2- ( (trifluoromethyl) sulfonyl) phenyl) amino) -4- (phenylthio) butyl) piperazin-1-yl) -7-oxoheptanamido) -3, 3-dimethylbutanoyl) -4-hydroxy-N- ( (S) -1- (4- (4-methylthiazol-5-yl) phenyl) ethyl) pyrrolidine-2-carboxamide. Canonical SMILES: CC1 (C) CCC (C2=CC=C (Cl) C=C2) =C (C1) CN3CCN (C4=CC=C (C (NS (=O) (C5=CC (S (C (F) (F) F) (=O) =O) =C (N[C@@H] (CSC6=CC=CC=C6) CCN7CCN (C (CCCCCC (N[C@@H] (C (C) (C) C) C (N8[C@@H] (C[C@@H] (O) C8) C (N[C@H] (C9=CC=C (C%10=C (N=CS%10) C) C=C9) C) =O) =O) =O) =O) CC7) C=C5) | |
| DUN99845 | DUN99845 is a a lifespan-altering agent. DUN99845 was first reported in patent US 20090163545. DUN99845 was also reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. Group: Inhibitors. Alternative Names: DUN99845; DUN-99845; DUN 99845. CAS No. 727699-84-5. Molecular formula: C26H21FN2O4S. Mole weight: 476.52. Appearance: Solid powder. Purity: >98%. IUPACName: N-[3-[[(4-Fluorophenyl)sulfonyl]amino]-4-methoxyphenyl][1,1'-biphenyl]-4-carboxamide. Canonical SMILES: O=C (C1=CC=C (C2=CC=CC=C2)C=C1)NC3=CC=C (OC)C (NS (=O) (C4=CC=C (F)C=C4)=O)=C3. Catalog: ACM727699845. | |
| Eltrombopag Amide | Eltrombopag Amide. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H23N5O3, Molecular Weight: 441.48. US Biological Life Sciences. | Worldwide |
| Eltrombopag Amide | Eltrombopag Amide is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: > 95%. CAS No. 1246929-02-1. Molecular formula: C25H23N5O3. Mole weight: 441.48. | |
| Eltrombopag Impurity 49 | Eltrombopag Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxamide. Molecular Formula: C13H12N2O2. Mole Weight: 228.25. Catalog: APB05604. | |
| Eltrombopag Impurity 5 | Eltrombopag Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxamide. CAS No. 1246929-02-1. Molecular Formula: C25H23N5O3. Mole Weight: 441.48. Catalog: APB1246929021. | |
| Eltrombopag Impurity 59 | Eltrombopag Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-N-(2-hydroxyethyl)-[1,1'-biphenyl]-3-carboxamide. Molecular Formula: C27H27N5O4. Mole Weight: 485.53. Catalog: APB05598. | |
| Eltrombopag Impurity 61 | Eltrombopag Impurity 61. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxamide. Molecular Formula: C25H23N5O3. Mole Weight: 441.18. Catalog: APB05594. | |
| Eltrombopag Impurity 70 | Eltrombopag Impurity 70. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-N-(2-hydroxyethyl)-[1,1'-biphenyl]-3-carboxamide. Molecular Formula: C27H27N5O4. Mole Weight: 485.21. Catalog: APB05590. | |
| Erismodegib | Erismodegib. Group: Biochemicals. Alternative Names: rel-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-1,1'-biphenyl]-3-carboxamide; LDE 225; NVP-LDE 225. Grades: Highly Purified. CAS No. 956697-53-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C26H26F3N3O3. US Biological Life Sciences. | Worldwide |
| GMC 15-27 | GMC 15-27 is a selective 5-HT1B/1D antagonist. Synonyms: 4'-(Aminoiminomethyl)-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-[1,1'-biphenyl]-4-carboxamide. Grades: 98%. CAS No. 256227-71-1. Molecular formula: C27H31N5O2. Mole weight: 457.57. | |
| GR 103691 | GR 103691 is a potent dopamine D3 receptor antagonist. Uses: Dopamine antagonists. Synonyms: GR 103691; GR103691; GR-103691; 4'-Acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide. Grades: 99%. CAS No. 162408-66-4. Molecular formula: C30H35N3O3. Mole weight: 485.62. | |
| GR 127935 hydrochloride | GR 127935 hydrochloride is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrochloride (1:1); [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, monohydrochloride; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide hydrochloride; GR127935 hydrochloride; GR-127935 hydrochloride. Grades: ≥99% by HPLC. CAS No. 148642-42-6. Molecular formula: C29H31N5O3.HCl. Mole weight: 534.06. | |
| GUN35901 | GUN35901 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. GUN35901 is a demethyl analogue of DUN99845 (CAT#556012). GUN35901 was first reported in patent CN 112057443. Group: Inhibitors. Alternative Names: GUN35901; GUN-35901; GUN 35901; SN-011; SN011; SN 011. CAS No. 2249435-90-1. Molecular formula: C25H19FN2O4S. Mole weight: 462.5. Appearance: Solid powder. Purity: >98%. IUPACName: N-(3-((4-fluorophenyl)sulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide. Catalog: ACM2249435901. | |
| Indimilast | Indimilast is a phosphodiesterase IV inhibitor. It modulates lung inflammation and cause bronchodilation by increasing intracellular cyclic adenosine 3', 5'-monophosphate in airway smooth muscle and inflammatory cells. It is potential useful in chronic obstructive pulmonary disease(COPD). Uses: Indimilast is potential useful in chronic obstructive pulmonary disease(copd). Synonyms: N-[4-[1-[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]-6-fluoro-2,4-dioxopyrido[2,3-d]pyrimidin-3-yl]cyclohexyl]-2-methyl-1,3-thiazole-4-carboxamide;N-{cis-4-[1-(4'-{[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl}[1,1'-biphenyl]-3-yl)-6-fluoro-2,4-dioxo-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl]cyclohexyl}-2-methyl-1,3-thiazole-4-carboxamide. Grades: >98 %. CAS No. 1038825-85-2. Molecular formula: C37H40FN7O3S. Mole weight: 681.83. | |
| JNJ-28312141 | JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. JNJ-28312141 represents a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events. Synonyms: JNJ28312141; JNJ 28312141; 4-cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl]-2-yl)-1H-imidazole-2-carboxamide. CAS No. 885692-52-4. Molecular formula: C26H32N6O2. Mole weight: 460.58. | |
| LLY-507 | LLY-507, a lysine N-methyltransferase, is a cell-active, small molecule, and selective inhibitor of Protein-lysine Methyltransferase SMYD2 (IC50 = 15 nM), with >100-fold selectivity for SMYD2 over 25 other methyltransferases including SMYD3, SUV420H1 and SUV420H2. Synonyms: LLY-507; LLY 507; LLY507; 5-cyano-2'-(4-(2-(3-methyl-1H-indol-1-yl)ethyl)piperazin-1-yl)-N-(3-(pyrrolidin-1-yl)propyl)-[1,1'-biphenyl]-3-carboxamide; LLY-507; LLY 507; LLY507. CAS No. 1793053-37-8. Molecular formula: C36H42N6O. Mole weight: 574.77. | |
| Lomitapide | Lomitapide. Group: Biochemicals. Alternative Names: N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide; AEGR 733; BMS 201038; BMS 201038-01; BMS 201238. Grades: Highly Purified. CAS No. 182431-12-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C39H37F6N3O2, Molecular Weight: 693.72. US Biological Life Sciences. | Worldwide |
| LY2183240 2'-isomer | LY2183240 2'-isomer is a 2,5-regioisomer of LY2183240 that inhibits anandamide hydrolysis and cellular reuptake. LY2183240 2'-isomer exhibits less potent activity than LY2183240. Synonyms: 5-([1,1'-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide; 5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide. Grades: ≥98%. CAS No. 1010096-65-7. Molecular formula: C17H17N5O. Mole weight: 307.4. | |
| MMP-9/MMP-13 Inhibitor I | MMP-9/MMP-13 inhibitor I is a selective and cell-permeable inhibitor of matrix metalloproteinases MMP-9/MMP-13 with IC50 values of 0.9 nM for both. It also less potently inhibits MMP-1, MMP-3, and MMP-7. Synonyms: Matrix Metalloproteinase-9/Matrix Metalloproteinase-13 Inhibitor I; N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4-biphenylcarbonyl)piperazine-2-carboxamide. Grades: ≥98%. CAS No. 204140-01-2. Molecular formula: C25H25N3O6S. Mole weight: 495.6. | |
| MRT-83 | This active molecular is a novel potent Smoothened antagonist. MRT-83 blocks Hedgehog (Hh) signaling in various assays and IC50 can be in nmol range, showing greater potency than cyclopamine, another Smoothened antagonist. MRT-83 efficiently antagonizes Hh signaling in vivo. MRT-83 will be useful for manipulating Hh signaling and may help develop new treatment for Hh-pathway related diseases. Uses: Hh-pathway related diseases. Synonyms: MRT-83; MRT 83; MRT83; N-[5-[[imino[ (3, 4, 5-trimethoxybenzoyl) amino]methyl]amino]-2-methylphenyl]-[1, 1'-Biphenyl]-4-carboxamide; 1359944-60-7 (HCl salt). Grades: 98%. CAS No. 1263131-92-5. Molecular formula: C31H30N4O5. Mole weight: 538.59. | |
| MRT-83 hydrochloride | MRT-83 is a Smoothened (Smo) antagonist. It can block Hedgehog (Hh) signaling in various assays. MRT-83 can also inhibit Bodipy-cyclopamine binding to human and mouse Smo. MRT-83 can efficiently antagonize Hh signaling in vivo. MRT-83 may help develop new therapies for the treatment of Hh-pathway related diseases. Uses: Hh-pathway related diseases. Synonyms: MRT-83 hydrochloride; MRT 83 hydrochloride; MRT83 hydrochloride; N-(2-methyl-5-(3-(3,4,5-trimethoxybenzoyl)guanidino)phenyl)-[1,1'-biphenyl]-4-carboxamide hydrochloride;1263131-92-5 (free base). Grades: 98%. CAS No. 1359944-60-7. Molecular formula: C31H31ClN4O5. Mole weight: 575.06. | |
| PF 9184 | This active molecular is selective mPGES-1 (microsomal prostaglandin E synthase-1 inhibitor. mPGES-1 is an enzyme induced during the inflammatory response and it is for developing anti-inflammatory drugs. PF-9184 inhibited recombinant human mPGES-1 with IC50 value of 16.5nM. PF-9184 had no effect against COX-1 and COX-2 with more than 6500-fold selectivity. PF-9184 inhibited PGE(2) synthesis with IC50 value in the range of 0.5-5 mM in serum-free cell and human whole blood cultures. Uses: Anti-inflammatory agent. Synonyms: N-(3',4'-Dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide. Grades: 98%. CAS No. 1221971-47-6. Molecular formula: C21H14Cl2N2O4S. Mole weight: 461.31. | |
| ROCK-IN-1 | A potent inhibitor of ROCK2 (IC50= 1.2 nM). Synonyms: [1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl-. CAS No. 934387-35-6. Molecular formula: C20H18FN3O. Mole weight: 335.37. | |
| SB 216641 hydrochloride | SB 216641 hydrochloride is a selective h5-HT1B antagonist with ~ 25-fold selectivity over h5-HT1D and little or no affinity for a range of other receptor types. Synonyms: SB216641 hydrochloride; SB-216641 hydrochloride; N-[3-[2-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide Monohydrochloride; [1,1'-Biphenyl]-4-carboxamide, N-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrochloride (1:1); [1,1'-Biphenyl]-4-carboxamide, N-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, monohydrochloride; SB 216641A; SB216641A; SB-216641A. Grades: ≥98% by HPLC. CAS No. 193611-67-5. Molecular formula: C28H30N4O4.HCl. Mole weight: 523.03. | |
| TCS 1102 | TCS 1102 is a potent, dual orexin receptor antagonist with Ki values of 0.2 and 3 nM for OX2 and OX1 receptors respectively. It is a poor substrate for P-glycoprotein, which demonstrates good brain penetration when administered intraperitoneally. It were found to decrease fear and anxiety in rats 14 days after exposure to footshock. It was also found to have anxiolytic effects that were specific for HR when tested in the elevated T-maze. Uses: Tcs 1102 was found to have anxiolytic effects. Synonyms: N-[1,1'-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl-2-pyrrolidinedicarboxamide;2-PyrrolidinecarboxaMide, N-[1,1'-biphenyl]-2-yl-1-[2-[(1-Methyl-1H-benziMidazol-2-yl)thio]acetyl]-, (2S)-;(2S)-N-[1,1'-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl]-2-pyrrolidinecarboxamide;TCS 1102, TCS1102, TCS-1102;(2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide. Grades: >98 %. CAS No. 916141-36-1. Molecular formula: C27H26N4O2S. Mole weight: 470.59. | |
| Telmisartan Bromo Amide Impurity | One of the impurities of Telmisartan, which is an angiotensin II receptor antagonist and could be used in the treatment of hypertensive. Synonyms: 4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide. Grades: > 95%. CAS No. 147404-72-6. Molecular formula: C14H12NBrO. Mole weight: 290.16. | |
| Vat Yellow 33 | Vat Dyes. Alternative Names: 4',4'''-azobis[n-(9,10-dihydro-9,10-dioxo-1-anthryl)]-[1,1'-biphenyl]-4-carboxamide;C.I. 65429;vat yellow 33;Vat yellow 33 (C.I. 65429);[1,1'-Biphenyl]-4-carboxamide, 4',4'''-azobis[N-(9,10-dihydro- 9,10-dioxo-1-anthracenyl)-;Yellow F3GC;Cibanone Yellow. CAS No. 12227-50-8. Molecular formula: C54H32N4O6. Mole weight: 832.86. Purity: 0.96. IUPACName: N-(9,10-dioxoanthracen-1-yl)-4-[4-[[4-[4-[(9,10-dioxoanthracen-1-yl)ca. Density: 1.35. Catalog: ACM12227508. | |
| [1,1'-Biphenyl]-4-carboximidamide | Heterocyclic Organic Compound. Alternative Names: BIPHENYL-4-CARBOXAMIDINE. CAS No. 125772-44-3. Molecular formula: C13H12N2. Mole weight: 196.25. Purity: 0.96. IUPACName: 4-phenylbenzenecarboximidamide. Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C(=N)N. Density: 1.1 g/cm³. Catalog: ACM125772443. | |
| 2-(1-(tert-butoxycarbonyl) pyrrolidine-2-carboxamido) -[1,1'-biphenyl]-4,4'- dicarboxylic acid | 2-(1-(tert-butoxycarbonyl) pyrrolidine-2-carboxamido) -[1,1'-biphenyl]-4,4'- dicarboxylic acid. Group: Carboxylic acid mof ligand-dicarboxylic acid mof ligand. CAS No. 1283676-82-3. Molecular formula: 640.34606. Mole weight: C25H24O12P4. |  |
| Biphenyl-4-carboxamidine hydrochloride | Heterocyclic Organic Compound. CAS No. 111082-23-6. Molecular formula: C13H13ClN2. Mole weight: 232.7121. Purity: 0.98. Catalog: ACM111082236. | |
| MK0686 | MK0686 is a bradykinin B1 receptor antagonist. It exhibits suitable pharmacokinetic properties and efficient ex vivo receptor occupancy for further development as a novel approach for the treatment of pain and inflammation. It had been in phase II clinical trials by Merck Sharp & Dohme for the treatment of postherpetic neuralgia, postoperative pain and osteoarthritis. But it is discontinued now. Uses: Mk0686 is used for the treatment of postherpetic neuralgia, postoperative pain and osteoarthritis. Synonyms: MK0686; MK 0686; MK-0686;Methyl 2-chloro-6- [3-fluoro-4- [ (1R) -1- [ [1- [ (2, 2, 2-trifluoroacetyl) amino] cyclopropanecarbonyl] amino] ethyl] phenyl] benzoate; Methyl (R)-3-chloro-3'-fluoro-4'-(1-(1-(2,2,2-trifluoroacetamido)cyclopropane-1-carboxamido)ethyl)-[1,1'-biphenyl]-2-carboxyla. Grades: 98%. CAS No. 578727-68-1. Molecular formula: C22H19ClF4N2O4. Mole weight: 486.85. | |
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