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Bivalirudin. Group: Biochemicals. Grades: Highly Purified. CAS No. 128270-60-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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Bivalirudin
Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI). It is a synthetic congener of the naturally occurring drug hirudin. It is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. It is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. It has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore, it has a predictable antithrombotic response. It does not require a binding cofactor such as antithrombin and does not activate platelets. Synonyms: Hirulog; Hirulog I; Angiomax; Hirulog-1; Hirulog1; Hirulog 1; BG8967; BG 8967; BG-8967; LS-172701; LS172701; LS 172701. Grades: > 95%. CAS No. 128270-60-0. Molecular formula: C98H138N24O33. Mole weight: 2180.32.
Bivalirudin Impurity 1 is an impurity of Bivalirudin which is an eminent anticoagulant, used to treat patients burdening heparin-induced thrombocytopenia. Grades: > 95%. CAS No. 72378-50-8. Molecular formula: C6H8N2O4. Mole weight: 172.14.
Bivalirudin Plus-Gly Fragment Trifluoroacetic Acid Salt (Impurity)
Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin. Uses: Scientific research. Group: Peptides. CAS No. 1191386-55-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15664.
Bivalirudin Trifluoroacetate
Bivalirudin is a specific and reversible bivalent direct thrombin inhibitor. Bivalirudin specifically binds to both the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Synonyms: Bivalirudin TFA; Bivalirudin TFA salt; H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH. Grades: >98%. Molecular formula: C100H138DF3N24O35. Mole weight: 2295.32.
[3-20} Bivalirudin is an impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C84H122N22O31 x(C2HF3O2). US Biological Life Sciences.