Bleomycin Suppliers USA
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Product | Description | |
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Bleomycin Quick inquiry Where to buy Suppliers range | colourless or light yellow powder. Group: Heterocyclic Organic Compound. Alternative Names: BLENOXANE;BLEO;BLEXANE;BLEOMYCIN SULFATE, STREPTOMYCES VERTICILLUS;BLEOMYCIN SULPHATE; Bleocin; BLM; N1- (3- (dimethylsulfonio) propyl) bleomycinamide) (Bleomycin A2). CAS No. 11056-06-7. Molecular formula: C55H84N17O21S3. Mole weight: 1415.55. Density: g/cm3. | |
Bleomycin Quick inquiry Where to buy Suppliers range | Bleomycin. CAS No. 11056-06-7. | |
Bleomycin a2 Quick inquiry Where to buy Suppliers range | Bleomycin a2. Group: Heterocyclic Organic Compound. Alternative Names: BLEOMYCIN A2;Bleomycinamide, N1-[3-(dimethylsulfonio)propyl]-;BLEMOYCIN AZ; Bleogin; N1-[3- (Dimethylsulfonio) propyl]bleomycinamide; Pingyangmycin A2;Zhengguangmycin A2;Einecs 234-356-5. CAS No. 11116-31-7. Molecular formula: C55H84N17O21S3+. Mole weight: 1415.55. | |
Bleomycin A2 Quick inquiry Where to buy Suppliers range | It is one of two components found in the glycopeptide antineoplastic antibiotic Bleomycin sulfate. Bleomycin sulfate is a chemotherapeutic agent used for the treatment of hodgkins lymphoma. It is isolated from the bacterium Streptomyces verticillus. Synonyms: Bleomycin a2; Bleomycinamide, N1-[3-(dimethylsulfonio)propyl]-; Bleogin; N1-[3- (Dimethylsulfonio) propyl]bleomycinamide; Pingyangmycin A2; Zhengguangmycin A2. Grades: ≥95.0%. CAS No. 11116-31-7. Molecular formula: C55H84N17O21S3. Mole weight: 1415.55. | |
Bleomycin A5 hydrochloride Quick inquiry Where to buy Suppliers range | Bleomycin A5 hydrochloride is an antitumor antibiotic which induces apoptosis. Synonyms: Bleomycin A5 HCl; N1- (3- ( (4-Aminobutyl) amino) propyl) bleomycinamide hydrochloride; Bleomycinamide, N(sup 1)-(3-((4-aminobutyl)amino)propyl)-, hydrochloride. CAS No. 55658-47-4. Molecular formula: C57H89CuN19O21S2.3HCl. Mole weight: 1477.02. | |
Bleomycin A5 Hydrochloride Quick inquiry Where to buy Suppliers range | Bleomycin A5 Hydrochloride. Group: Biochemicals. Alternative Names: N1- [3- [ (4-Aminobutyl) amino] propyl] bleomycinamide Hydrochloride. Grades: Highly Purified. CAS No. 55658-47-4. Pack Sizes: 5mg. Molecular Formula: C57H90ClN19O21S2, Molecular Weight: 1477.02. US Biological Life Sciences. | Worldwide |
Bleomycin A6 Quick inquiry Where to buy Suppliers range | Bleomycin is a glycopeptide anti-tumor antibiotic produced by Streptomyces verticillus B-80-Z2. It has anti-gram-positive bacteria, negative bacteria, and mycobacterial activity, and is particularly active against Mycobacterium phlei. Synonyms: zhengguangmycin A6. CAS No. 37293-17-7. Molecular formula: C60H96N20O21S2. Mole weight: 1497.65. | |
Bleomycin b2 Quick inquiry Where to buy Suppliers range | Bleomycin b2. Group: Heterocyclic Organic Compound. Alternative Names: Bleomycin B2;BLEMOYCIN BZ;Dehydrophleomycin D1; N1-[4-[ (Aminoiminomethyl) amino]butyl]bleomycinamide; N1-[4-[[Amino (imino) methyl]amino]butyl]bleomycinamide; Phleomycin D2;Zhengguanmycin B2. CAS No. 9060-10-0. Molecular formula: C55H84N20O21S2. Mole weight: 1425.52. | |
Bleomycin complex (as sulfate salts) Quick inquiry Where to buy Suppliers range | Bleomycin is a complex of 11 glycopeptide antitumor antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2 and typically represent >90% of the total weight with the remainder comprising the minor analogues. Bleomycins have found clinical application in the treatment of a range of tumors. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo- enzyme that induces DNA cleavage. Group: Biochemicals. Alternative Names: Blenoxane; Blexane; Bleo. Grades: Highly Purified. CAS No. 9041-93-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Bleomycin hydrochloride Quick inquiry Where to buy Suppliers range | Bleomycin hydrochloride. Uses: Use as pharmaceutical ingredient. Alternative Names: Bleomycin, hydrochloride. CAS No. 67763-87-5. Product ID: ACM67763875. Molecular formula: C50< / sub>H71< / sub>N16< / sub>O21< / sub>S2< / sub>R?x (HCl). Mole weight: Unspecified. | |
BLEOMYCINS Quick inquiry Where to buy Suppliers range | BLEOMYCINS. CAS No. 9041-93-4. | |
Bleomycin Sulfate Quick inquiry Where to buy Suppliers range | 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: N/A. CAS No. 9041-93-4. Prepack ID 25097489-10mg. See USA prepack pricing. | |
Bleomycin Sulfate (A2, B2) Quick inquiry Where to buy Suppliers range | A group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically. Antineoplastic. Mixture of Bleomycin A2, B2 isolated from Streptomyces verticillus. Group: Biochemicals. Alternative Names: Blenoxane; Blexane; Bleo. Grades: Purified. CAS No. 9041-93-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C55H84N17O21S3·xH2SO4, Molecular Weight: 1415.56 (free acid basis). US Biological Life Sciences. | Worldwide |
AM095 Quick inquiry Where to buy Suppliers range | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Synonyms: AM095 (free acid); AM-095; AM 095. Grades: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49. | |
AS-605240 Quick inquiry Where to buy Suppliers range | AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory diseases. Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis. Synonyms: AS 605240; AS605240; AS-605240. Grades: 0.98. CAS No. 648450-29-7. Molecular formula: C12H7N3O2S. Mole weight: 257.267. | |
AUDA Quick inquiry Where to buy Suppliers range | AUDA is an inhibitor of soluble epoxide hydrolase with IC50 of 18 nM in mice. AUDA has been shown to demonstrate hypotensive effects, accompanied by an increase in urinary epoxide-to-diol ratios. AUDA can activate peroxisome proliferator-activated receptor α (PPARα) 3-fold, while showing no ability to affect PPARδ or PPAR&gamma. AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways. Synonyms: 12-(3-Adamantan-1-yl-ureido)dodecanoic Acid; 12-[[(Tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]dodecanoic Acid; A 003564556. Grades: >98%. CAS No. 479413-70-2. Molecular formula: C23H40N2O3. Mole weight: 392.6. | |
Boanmycin Hydrochloride Liposome Quick inquiry Where to buy Suppliers range | Boanmycin hydrochloride is consistent with bleomycin A6 and has a broad anticancer spectrum without significant myelosuppression. This product is a pre-formulated liposome with boanmycin hydrochloride. It is only for research purposes. Group: Drug-loaded liposome. | |
Boromycin (Antibiotic A 28829, Ivomycin, NSC216128) Quick inquiry Where to buy Suppliers range | Boron-containing macrolide antibiotic. Antibacterial. Antiprotozoal (Plasmodium, Babesia). Anti-HIV compound. Ca2+ homeostasis modulator. Potentiator of bleomycin-induced anti-tumor activity. Used as a chiral selector in capillary electrophoresis.CAS Number:34524-20-4. Group: Biochemicals. Grades: Highly Purified. CAS No. 34524-20-4. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
CCG 232601 Quick inquiry Where to buy Suppliers range | CCG 232601 is a selective and orally bioactive inhibitor of the Rho/MRTF/SRF signaling pathway (IC50 value of 0.55 μM (SRE.L assay)) as a potential antifibrotic therapeutic for systemic scleroderma. CCG-232601 inhibits the development of bleomycin-induced dermal fibrosis in mice when administered orally. Synonyms: N-(4-chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide; CCG-232601; CCG 232601; CCG232601. Grades: 99%. CAS No. 1922099-21-5. Molecular formula: C24H20ClF2N3O2. Mole weight: 455.88. | |
cis-Diamineplatinum(II) dichloride Quick inquiry Where to buy Suppliers range | cis-Diamineplatinum(II) dichloride. Uses: Cisplatin is a cytostatic agent and it is used to treat various cancer types, including cancer of ovary, testis, lung, head, neck, bladder, neuroblastoma, and nephroblastoma, and Hodgkin's disease and non-Hodgkin lymphoma.CDDP, also referred to as cisplatinum or cisplatin, is a yellow powder and has found widespread use a chemotherapeutic agent.Cisplatin, combined with bleomycin and vinblastine or etoposide, produces cures in most patients with metastatic testicular cancer or germ cell cancer of the ovary. Cisplatin also shows some activity against carcinomas of the head and neck, bladder, cervix, prostate, and lung. Group: Platinum series of catalysts. Alternative Names: cis-Dichlorodiammine platinum(II). Grades: Pt ≥65.0%. CAS No. 15663-27-1. Product ID: ACM15663271. Molecular formula: Pt(NH3)2Cl2. Mole weight: 300.05. Appearance: yellow crystals. Melting Point: 270 °C(lit.). | |
Cleomycin A2 Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces verticillus NK-68-144. It has anti-mycobacterial and HeLa cell activity. Synonyms: 3S, S-Dimethylmercaptopropyl aminocleomycin; Bleomycinamide, 16-de(1-hydroxyethyl)-N1-(3-(dimethylsulfonio)propyl)-16-(1-hydroxycyclopropyl)-. CAS No. 754137-61-6. Molecular formula: C56H84N17O21S3. Mole weight: 1427.56. | |
Cleomycin B2 Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces vericillus NK68-144. Cleomycin B2 has the same structure as the corresponding bleomycin. Synonyms: Bleomycinamide, N(1)-(4-((aminoiminomethyl)amino)butyl)-16-de(1-hydroxyethyl)-16-(1-hydroxycyclopropyl)-, (16S)-. CAS No. 76741-88-3. Molecular formula: C56H84N20O21S2. Mole weight: 1437.51. | |
Demethylbleomycin A2 sulfate Quick inquiry Where to buy Suppliers range | A demethylated form of bleomycin A2 which is a major component in standard grade bleomycin. It is formed by heating bleomycin A2. It has high antimicrobial activity against mycobacterium smegmatis compared to bleomycin A2. It has a lower toxicity. Synonyms: Bleomycin DM-A2 sulfate; N1-[3-(Methylthio)propyl]bleomycinamide sulfate. Grades: ≥90%. Molecular formula: C54H81N17O21S3.xH2SO4. Mole weight: 1400.51 (free base). | |
FR-167653 Quick inquiry Where to buy Suppliers range | FR-167653 is a p38 mitogen-activated protein kinase inhibitor, which suppresses the development of endometriosis in a murine model. FR-167653 meliorates murine bleomycin-induced pulmonary fibrosis. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: FR-167653; FR 167653; FR167653. CAS No. 158876-66-5. Molecular formula: C24H20FN5O6S. Mole weight: 525.51. | |
H-Arg-Ala-OH Quick inquiry Where to buy Suppliers range | Arg-Ala inhibits angiotensin 1-converting enzyme (ACE) and yeast bleomycin hydrolase. Synonyms: Arginylalanine; Arg-Ala; L-arginyl-L-alanine; RA dipeptide; N-L-Arginyl-L-alanine; Arginine Alanine dipeptide; (S)-2-((S)-2-Amino-5-guanidinopentanamido)propanoic acid. CAS No. 40968-45-4. Molecular formula: C9H19N5O3. Mole weight: 245.28. | |
Lactoquinomycin A Quick inquiry Where to buy Suppliers range | It is produced by the strain of Str. tanashiensis IM 8442T. It's a quinone antibiotic. It has the activity of anti-gram-positive bacteria and some gram-negative bacteria, but the effect of anti-gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin A has stronger antibacterial activity than Lactoquinomycin B. It inhibits a variety of cell lines including lymphoma L5178Y progenitor, adriamycin resistant, bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013 and 0.03, respectively. Synonyms: Lactoquinomycin A; Medermycin; [3aS,(-)]-3,3aβ,5,11bβ-Tetrahydro-7-hydroxy-5β-methyl-8-[3-(dimethylamino)-2,3,6-trideoxy-L-arabino-hexopyranosyl]-2H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11-trione; Antibiotic K 73A; 2H-Furo[3,2-b]naphtho[2,3-d]pyran-2,6,11-trione,3,3a,5,11b-tetrahydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-beta-D-arabino-hexopyranosyl]-, (3aR,5R,11bR)-. Grades: 95%. CAS No. 60227-09-0. Molecular formula: C24H27NO8. Mole weight: 457.48. | |
Lactoquinomycin B Quick inquiry Where to buy Suppliers range | It is produced by the strain of Str. tanashiensis IM 8442T. It's a quinone antibiotic. It has the activity of anti-gram-positive bacteria and some gram-negative bacteria, but the effect of anti-gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin A has stronger antibacterial activity than Lactoquinomycin B. It inhibits a variety of cell lines including lymphoma L5178Y progenitor, adriamycin resistant, bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively. Synonyms: 3a,11b-Dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-β-D-arabino-hexopyranosyl]-5a,11a-epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione; 5a,11a-Epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione, 3a,11b-dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-b-D-arabino-hexopyranosyl]-. CAS No. 101342-94-3. Molecular formula: C24H27NO9. Mole weight: 473.48. | |
LL D05139(beta) Quick inquiry Where to buy Suppliers range | LL D05139(beta) is produced by the strain of Glycomyces harbinensis. It has anti-gram-positive and anti-gram-negative bacteria activities, and its activity is stronger than that of nitroserine. And its antitumor activity is similar to that of diazoserine and lower than Bleomycin. Synonyms: N-(L-alanyl)-O-(2-diazoacetyl)-L-serine; N-l-alanyl-l-serine diazoacetate. CAS No. 95153-19-8. Molecular formula: C8H12N4O5. Mole weight: 244.20. | |
Malformin C Quick inquiry Where to buy Suppliers range | Peptide antibiotic. Induces root curvature and malformation in plants. Antibacterial, antimalarial and antitrypanosomal. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents.Malformin C is a bicyclic pentapeptide containing L-leucine, D-isoleucine, L-valine, and two D-cysteines coupled with a disulfide-bond bridge. Malformins A1 and C, originally isolated from the culture broth of Aspergillus niger FKI-2342, were found to abrogate the bleomycin-induced G2 arrest in Jurkat cells with IC50 values of 480nM and 0.9nM, respectively. Malformins may be promising candidates as anti-cancer agents. Source:Synthetic. Originally isolated from Aspergillus niger FKI-2342. Group: Biochemicals. Grades: Highly Purified. CAS No. 59926-78-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C23H39N5O5S2. US Biological Life Sciences. | Worldwide |
Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride (Methyl 2- (S) -[N-[ (Benzyloxy) carbonyl]amino-3-aminopropionate, Hydrochloride) Quick inquiry Where to buy Suppliers range | Important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins. Group: Biochemicals. Alternative Names: Methyl 2- (S) -[N-[ (Benzyloxy) carbonyl]amino-3-aminopropionate, Hydrochloride. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
Methyl 2- (S) - [N-Carbobenzyloxy] amino-3- [N-tert-butyloxycarbonyl] aminopropionate Quick inquiry Where to buy Suppliers range | Important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
Na-Carbobenzyloxy-b-amino-L-alanine (CBZ-L-b-Aminoalanine) Quick inquiry Where to buy Suppliers range | Important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins. Group: Biochemicals. Alternative Names: CBZ-L-b-Aminoalanine. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
N-α-Carbobenzoxy-L-α,β-diaminopropionic acid methyl ester hydrochloride Quick inquiry Where to buy Suppliers range | Important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins. Uses: Important building block for the synthesis of peptides containing dap residues, e.g. bleomycins, edeines, tuberactinomycins. Synonyms: Z-Dap-OMe HCl. Grades: ≥ 98.5% (HPLC). CAS No. 35761-27-4. Molecular formula: C12H17ClN2O4. Mole weight: 288.73. | |
Nα-Z-L-2,3-diaminopropionic acid Quick inquiry Where to buy Suppliers range | . Uses: Important building block for the synthesis of peptides containing dap residues, e.g. bleomycins, edeines, tuberactinomycins. Synonyms: Z-L-Dap-OH. Grades: ≥ 98% (Assay). CAS No. 35761-26-3. Molecular formula: C11H14N2O4. Mole weight: 238.48. | |
NCX 466 Quick inquiry Where to buy Suppliers range | NCX 466 is a cyclooxygenase inhibiting nitric oxide donors (CINODs). NCX 466 shows higher efficacy in reducing levels of profibrotic cytokine transforming growth factor-β and oxidative stress in a mouse model of bleomycin-induced lung fibrosis camparing to naproxen. Synonyms: (αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid (5S)-5,6-bis(nitrooxy)hexyl ester. Grades: ≥98% by HPLC. CAS No. 1262956-64-8. Molecular formula: C20H24N2O9. Mole weight: 436.41. | |
NCX 466 ((aS)-6-Methoxy-a-methyl-2-naphthalene acetic acid (5S)-5,6-bis(nitrooxy)hexyl ester) Quick inquiry Where to buy Suppliers range | Cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor (CINOD). Inhibits COX-1 and COX-2 while releasing NO. Demonstrates higher efficacy than naproxen, its congener drug, in reducing levels of profibrotic cytokine transforming growth factor-beta and oxidative stress in a mouse model of bleomycin-induced lung fibrosis. Orally available. Group: Biochemicals. Grades: Highly Purified. CAS No. 1262956-64-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
NU1025 Quick inquiry Where to buy Suppliers range | NU1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. NU1025 enhanced the cytotoxicity of the DNA-methylating agent MTIC, gamma-irradiation and bleomycin 3.5-, 1.4- and 2-fold respectively. Synonyms: NU-1025; NU 1025; 8-Hydroxy-2-methylquinazoline-4-one; NSC 696807. Grades: ≥98%. CAS No. 90417-38-2. Molecular formula: C9H8N2O2. Mole weight: 176.17. | |
PEPLEOMYCIN SULFATE Quick inquiry Where to buy Suppliers range | Peplomycin is a semisynthetic analog of Bleomycin. It is a mixture of several basic glycopeptide antineoplastic antibiotics that isolated from the fungus Streptomyces verticillus. Peplomycin can form complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals. This leads to single- and double-stranded breaks in DNA. Peplomycin is a DNA synthesis inhibitor and has been used for the treatment of a various of Malignancies. Uses: Malignancies. Synonyms: N1- [3- [ [ (1S) -1-phenylethyl] amino] propyl] bleomycinamide Sulfate; NK 631; NSC-276382. Grades: 98%. CAS No. 70384-29-1. Molecular formula: C61H90N18O25S3. Mole weight: 1571.67. | |
Peplomycin Quick inquiry Where to buy Suppliers range | Peplomycin is an extensively-researched compound aiding in studying a wide spectrum of malignancies encompassing pulmonary, mammary and gastric carcinomas. Uses: Antibiotics, antineoplastic. Synonyms: Pepleo; Bleomycin PEP; N(sup 1) - (3- ( (1-Phenylethyl) amino) propyl) bleomycinamide. Grades: >98%. CAS No. 68247-85-8. Molecular formula: C61H88N18O21S2. Mole weight: 1473.59. | |
Peplomycin sulfate Quick inquiry Where to buy Suppliers range | Peplomycin sulfate. Group: Biochemicals. Alternative Names: N1- [3- [ [ (1S) -1-phenylethyl] amino] propyl] bleomycinamide. Grades: Highly Purified. CAS No. 70384-29-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C61H90N18O25S3. US Biological Life Sciences. | Worldwide |
Phleomycin Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. The therapeutic index of the complex for Solid Adenocarcinoma and Sarcoma-180 are 16. The therapeutic index of Ehrlician ascites cancer is 4-8. It acts an antibiotic originally, an anticancer agent and a selection agent for transformed algae, protista, animal and fungal cells. Synonyms: Bleomycin; phleomycin complex; Phleomycins. CAS No. 11006-33-0. Molecular formula: C51H75N17O21S2. Mole weight: 1326.37. | |
Phleomycin B2 Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. Synonyms: Epi-Bleomycin; Dehydrophleomycin D1; Zhengguanmycin B2; N1-[4-[[Amino (imino) methyl]amino]butyl]bleomycinamide; Bleomycin B2; Bleomycinamide, N1-(4-((aminoiminomethyl)amino)butyl)-. CAS No. 9060-10-0. Molecular formula: C55H84N20O21S2. Mole weight: 1425.51. | |
Phleomycin D1 Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 12.5-25 μg/mL. It inhibits airy entity carcinoma in mice with IC50 of 0.31 μg/mL. Synonyms: Zeocin; Zeocine; (7R)-N1-[4-[[Amino(imino)methyl]amino]butyl]-7,8-dihydrobleomycinamide; Bleomycinamide, N1-[4-[(aminoiminomethyl)amino]butyl]-7,8-dihydro-. Grades: 95%. CAS No. 11031-11-1. Molecular formula: C55H86N20O21S2. Mole weight: 1427.52. | |
Phleomycin E Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 12.5-25 μg/mL. It inhibits airy entity carcinoma in mice with IC50 of 0.31 μg/mL. Synonyms: N1- [4- [ [ [ [4- [ [Aminoiminomethyl]amino]butyl]amino] (imino) methyl]amino]butyl]-7, 8-dihydrobleomycinamide; Bleomycinamide, N1- [4- [ [ [ [4- [ (aminoiminomethyl) amino] butyl] amino] iminomethyl] amino] butyl] -7, 8-dihydro-. CAS No. 11031-13-3. Molecular formula: C60H97N23O21S2. Mole weight: 1540.68. | |
Phleomycin F Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 25-50 μg/mL. Synonyms: Bleomycin B4; Dehydrophleomycin E; N1- [4- [ (Aminoiminomethyl) [4- [ (aminoiminomethyl) amino] butyl] amino] butyl] bleomycinamide; Bleomycinamide, N1-[4-[ (aminoiminomethyl) [4-[ (aminoiminomethyl) amino]butyl]amino]butyl]-. CAS No. 9060-11-1. Molecular formula: C60H95N23O21S2. Mole weight: 1538.67. | |
SPL 334 Quick inquiry Where to buy Suppliers range | SPL 334 is an S-nitrosoglutathione reductase inhibitor that prevents weight loss, and alleviates lung inflammation and fibrosis in a bleomycin injury model of interstitial lung disease in mice. Synonyms: SPL-334; SPL334; SPL 334; 4-[[2-[[(2-Cyanophenyl)methyl]thio]-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 688347-51-5. Molecular formula: C22H15N3O3S2. Mole weight: 433.5. | |
Tallysomycin A Quick inquiry Where to buy Suppliers range | Talisomycin (former trivial name: tallysomycin A), a third generation bleomycin analog that was studied as an antitumor antibiotic. The drug cleaved DNA preferentially at G-C and G-T sequences and produced specific cleavages at G-A sequences. Uses: Microbial Fermentation Products. CAS No. 65057-90-1. Product ID: MFP-043. | |
Vesnarinone Quick inquiry Where to buy Suppliers range | Vesnarinone, a quinolinone derivative, is a cardiotonic agent. It has pharmacodynamic effects include inhibition of phosphodiesterase III (PDE3) activity, increases in calcium flux and decreases in potassium flux. Its IC50 value is 1 μM and 300 μM for inhibition of HERG channels and PDE. It is a novel cytokine inhibitor, for the treatment of lung fibrosis using a murine model of bleomycin (BLM)-induced pulmonary fibrosis. It is a new and novel inotropic drug that has unique and complex mechanisms of action. It inhibits phosphodiesterase, thereby leading to increased intracellular calcium, and also affects numerous myocardial ion channels, resulting in the prolongation of the opening time of sodium channels and the decrease in the delayed outward and inward rectifying potassium current. It plays an important role in the regulation of cytokines and suggests that the reduction of cytokine release may contribute to the beneficial effects of the drug in the treatment of heart failure. It inhibits the production of TFN-a and IFN-y by LPS stimulated whole blood from patients with heart failure and from healthy volunteers. Uses: Vesnarinone inhibits phosphodiesterase, thereby leading to increased intracellular calcium, and also affects numerous myocardial ion channels, resulting in the prolongation of the opening time of sodium channels and the decrease in the delayed outward and inward rectifying potassium current. it improves ventricular performance most in patients with the worst degree of heart failure. Synonyms: RG-0210; RG 0210; RG0210; OPC-8212; OPC 8212; OPC8212; Piteranometozine; Vesnarinone; Arkin; Arkin-Z. OPC 8212;6-[4-(3,4-Dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone;3,4-Dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-piperazinyl)-2(1h)-quinolinone. Grades: >98%. CAS No. 81840-15-5. Molecular formula: C22H25N3O4. Mole weight: 395.45. |