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1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C27H29N5O6S. CAS No. 147536-97-8. Prepack ID 54399509-1g. Molecular Weight 551.61. See USA prepack pricing.
Bosentan
A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N- [6- (2-hydroxyethoxy) -5- (o-methoxyphenoxy) -2- (2-pyrimidinyl) -4-pyrimidinyl] benzenesulfonamide; Actelion; Ro 47-0203; Ro 47-0203/039; Tracleer. Grades: Highly Purified. CAS No. 147536-97-8. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C27H29N5O6S, Molecular Weight: 551.62. US Biological Life Sciences.
Worldwide
Bosentan
Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 147536-97-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013.
Bosentan
Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Synonyms: Ro 47-0203. Grades: >98%. CAS No. 147536-97-8. Molecular formula: C27H29N5O6S. Mole weight: 551.61.
A labeled mixed endothelin receptor antagonist. Used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Bosentan Formate
Bosentan Formate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((6-(4-(tert-butyl)phenylsulfonamido)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethyl formate. CAS No. 301646-61-7. Molecular Formula: C28H29N5O7S. Mole Weight: 579.18. Catalog: APB301646617.
Bosentan hydrate
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H29N5O6S. H2O. CAS No. 157212-55-0. Prepack ID 20114584-1g. Molecular Weight 569.63. See USA prepack pricing.
Bosentan hydrate
Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 157212-55-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013A.
Bosentan hydrate
Bosentan inhibits the presser response to big ET-1 both after i.v. and oral administration, with a long duration of action and no intrinsic agonist activity. Synonyms: Ro 47-0203; Ro 470203; Ro470203; Ro-470203. Grades: >98%. CAS No. 157212-55-0. Molecular formula: C27H29N5O6S.H2O. Mole weight: 569.63.
Bosentan Hydrate
Bosentan Hydrate. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide Hydrate (1:1). Grades: Highly Purified. CAS No. 157212-55-0. Pack Sizes: 25mg. Molecular Formula: C27H31N5O7S, Molecular Weight: 569.63. US Biological Life Sciences.
Worldwide
Bosentan impurity 1
Bosentan impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1065472-77-6. Molecular Formula: C27H25D4N5O6S. Mole Weight: 555.64. Catalog: APB1065472776.
Bosentan Impurity 1
Bosentan Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine. CAS No. 150728-13-5. Molecular Formula: C15H10Cl2N4O2. Mole Weight: 349.17. Catalog: APB150728135.
Bosentan impurity 2
Bosentan impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H27N5O5S. Mole Weight: 521.59. Catalog: APB11805.
Bosentan Impurity 2
Bosentan Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butyl)benzenesulfonamide. CAS No. 6292-59-7. Molecular Formula: C10H15NO2S. Mole Weight: 213.3. Catalog: APB6292597.
Bosentan impurity 3
Bosentan impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 253688-60-7. Molecular Formula: C27H29N5O7S. Mole Weight: 567.62. Catalog: APB253688607.
Bosentan Impurity 3
Bosentan Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butyl)-N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide. CAS No. 150727-06-3. Molecular Formula: C25H24ClN5O4S. Mole Weight: 526.01. Catalog: APB150727063.
Bosentan impurity 4
Bosentan impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 253688-62-9. Molecular Formula: C26H27N5O7S. Mole Weight: 553.59. Catalog: APB253688629.
Bosentan impurity 5
Bosentan impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 253688-61-8. Molecular Formula: C26H27N5O6S. Mole Weight: 537.59. Catalog: APB253688618.
Bosentan impurity 7
Bosentan impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1355251-10-3. Molecular Formula: C20H27NO4S2. Mole Weight: 409.56. Catalog: APB1355251103.
Bosentan impurity 8
Bosentan impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 193013-72-8. Molecular Formula: C10H15NO2S. Mole Weight: 213.3. Catalog: APB193013728.
Bosentan Impurity D
Bosentan Impurity D is an impurity of Bosentan. Synonyms: O-Deshydroxyethyl Bosentan; N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide; 4-tert-Butyl-N-[6-hydroxy-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide. Grades: > 95%. CAS No. 174227-14-6. Molecular formula: C25H25N5O5S. Mole weight: 507.57.
Bosentan Monohydrate
Bosentan Monohydrate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate. Molecular Formula: C27H29N5O6S·H2O. Mole Weight: 569.19. Catalog: APB03689.
Bosentan Related Compound 1
Synonyms: 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine; Bosentan Related Compound D; 4,6-Dichloro-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)pyrimidine; Bosentan Related Compound D USP. Grades: > 95%. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.18.
Bosentan Related Compound 2
Bosentan Related Compound 2 is an intermediate as well as a degradation impurity of the endothelin receptor antagonist Bosentan. Synonyms: 4-tert-Butylbenzenesulfonamide; 4-(1,1-Dimethylethyl)benzenesulfonamide; p-tert-butyl-Benzenesulfonamide; NSC 9911. Grades: > 95%. CAS No. 6292-59-7. Molecular formula: C10H15NO2S. Mole weight: 213.30.
Bosentan Related Compound 3
Bosentan Related Compound 3 is an intermediate of Bosentan. Synonyms: N-[6-Chloro-5-(2-methoxyphenoxy)-(2,2-bipyrimidine)4-4-yl]-(1,1-dimethylethyl)-benzenesulfonamide; 4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzeneSulfonamide. Grades: > 95%. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.02.
Bosentan Related Compound C
Bosentan Related Compound C is an impurity of Bosentan. Synonyms: N,N'-[1,2-Ethanediylbis[oxy[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-6,4-diyl]]]bis[4-(1,1-dimethylethyl)-benzenesulfonamide; 1,2-Bis({6-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl}oxy)ethane; Bosentan dimer. Grades: > 95%. CAS No. 1097263-60-9. Molecular formula: C52H52N10O10S2. Mole weight: 1041.18.
Bosentan sec-butyl ether
Bosentan sec-butyl ether. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(6-(2-(sec-butoxy)ethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(tert-butyl)benzenesulfonamide. Molecular Formula: C31H37N5O6S. Mole Weight: 607.25. Catalog: APB03688.
Bosentan tert-butyl ether
Bosentan tert-butyl ether. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(6-(2-(tert-butoxy)ethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(tert-butyl)benzenesulfonamide. CAS No. 301646-60-6. Molecular Formula: C31H37N5O6S. Mole Weight: 607.25. Catalog: APB301646606.
Bosentan USP Related Compound B
Bosentan USP Related Compound B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butyl)-N-(5-(2-methoxyphenoxy)-6-oxo-3,6-dihydro-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide. CAS No. 174227-14-6. Molecular Formula: C25H25N5O5S. Mole Weight: 507.56. Catalog: APB174227146.
Bosentan USP Related Compound C
Bosentan USP Related Compound C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N,N'-(6,6''-(ethane-1,2-diylbis(oxy))bis(5-(2-methoxyphenoxy)-[2,2'-bipyrimidine]-6,4-diyl))bis(4-(tert-butyl)benzenesulfonamide). CAS No. 1097263-60-9. Molecular Formula: C52H52N10O10S2. Mole Weight: 1040.33. Catalog: APB1097263609.
Desmethyl bosentan
Desmethyl bosentan. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; Ro 47-8634. Grades: Highly Purified. CAS No. 253688-61-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C26H27N5O6S. US Biological Life Sciences.
Worldwide
Desmethyl Bosentan
Desmethyl Bosentan is a metabolite of Bosentan. Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; Ro 47-8634. Grades: > 95%. CAS No. 253688-61-8. Molecular formula: C26H27N5O6S. Mole weight: 537.60.
A metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 253688-61-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desmethyl Bosentan-d4
Desmethyl Bosentan-d4. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide-d4; Ro 47-8634. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C26H23D4N5O6S, Molecular Weight: 541.61. US Biological Life Sciences.
Worldwide
Hydroxy bosentan
Hydroxy bosentan. Group: Biochemicals. Alternative Names: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634; Ro 48-5033. Grades: Highly Purified. CAS No. 253688-60-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H29N5O7S. US Biological Life Sciences.
Worldwide
Hydroxy Bosentan
Hydroxy Bosentan is a metabolite of Bosentan. Synonyms: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634; Ro 48-5033. Grades: > 95%. CAS No. 253688-60-7. Molecular formula: C27H29N5O7S. Mole weight: 567.63.
Hydroxy bosentan-d4
Heterocyclic Organic Compound. Alternative Names: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d4; Ro 48-5033-d4. CAS No. 1065472-91-4. Molecular formula: C27H25D4N5O7S. Mole weight: 571.64. Appearance: White Solid. Catalog: ACM1065472914.
Hydroxy Bosentan-d4
A labeled analogue of the active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d4; Ro 48-5033-d4. Grades: Highly Purified. CAS No. 1065472-91-4. Pack Sizes: 1mg. US Biological Life Sciences.
A metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Group: Biochemicals. Alternative Names: Ro 48-5033. Grades: Highly Purified. CAS No. 253688-60-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Hydroxy Desmethyl Bosentan
A metabolite of Bosentan. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Hydroxy Desmethyl Bosentan-d4
Hydroxy Desmethyl Bosentan-d4. Group: Biochemicals. Alternative Names: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An intermediate of Bosentan, which is a mixed endothelin receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Nebentan potassium
Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ET A receptor antagonist through the modification of Bosentan (HY-A0013). Nebentan potassium inhibits [ 125 I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with K i of 0.697 nM and 569 nM, respectively [1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM598. CAS No. 342005-82-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106994A.
Tezosentan
Tezosentan, also known as RO 610612 and Veletri, is a potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan (B675900). It acts as a vasodilator and is used in the treatment of congestive heart failure. Synonyms: N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-propan-2-ylpyridine-2-sulfonamide5-isopropyl-pyridine-2-sulfonic acid 6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-1H-tetrazol-5-yl--pyridin-4-yl)--pyrimidin-4-ylamide; RO 61-0612; RO 610612; RO610612; tezosentan; Veletri. Grades: 95%. CAS No. 180384-57-0. Molecular formula: C27H27N9O6S. Mole weight: 605.63.
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