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| Product | Description | |
|---|---|---|
| Bosentan | 1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C27H29N5O6S. CAS No. 147536-97-8. Prepack ID 54399509-1g. Molecular Weight 551.61. See USA prepack pricing. |  |
| Bosentan | A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N- [6- (2-hydroxyethoxy) -5- (o-methoxyphenoxy) -2- (2-pyrimidinyl) -4-pyrimidinyl] benzenesulfonamide; Actelion; Ro 47-0203; Ro 47-0203/039; Tracleer. Grades: Highly Purified. CAS No. 147536-97-8. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C27H29N5O6S, Molecular Weight: 551.62. US Biological Life Sciences. |  Worldwide |
| Bosentan | Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 147536-97-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013. |  |
| Bosentan | Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Synonyms: Ro 47-0203. Grade: >98%. CAS No. 147536-97-8. Molecular formula: C27H29N5O6S. Mole weight: 551.61. |  |
| Bosentan | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| Bosentan-[13C2,d4] | Bosentan-[13C2,d4] is the labeled analogue of Bosentan, a mixed endothelin receptor antagonist used as a vasodilator. Synonyms: 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy-1,2-13C2-1,1,2,2-d4)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide; 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy-13C2,d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N-[6-(2-hydroxyethoxy-13C2,d4)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide; Actelion-13C2,d4; Ro 47-0203-13C2,d4; Ro 47-0203/039-13C2,d4; Tracleer-13C2,d4; Bosentan-13C2,d4. Grade: >95%. Molecular formula: C25[13C]2H25D4N5O6S. Mole weight: 557.62. | |
| Bosentan-[d4] | Bosentan-[d4] is the labelled analogue of Bosentan. Bosentan is an endothelin receptor antagonist indicated for pulmonary artery hypertension (PAH). Synonyms: Bosentan D4; 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N-[6-(2-hydroxyethoxy-d4)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide; Actelion-d4; Ro 47-0203-d4; Tracleer-d4. Grade: ≥96% by HPLC; ≥99% atom D. CAS No. 1065472-77-6. Molecular formula: C27H25D4N5O6S. Mole weight: 555.65. | |
| Bosentan-d4 (4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide) | A labeled mixed endothelin receptor antagonist. Used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bosentan hydrate | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H29N5O6S. H2O. CAS No. 157212-55-0. Prepack ID 20114584-1g. Molecular Weight 569.63. See USA prepack pricing. | |
| Bosentan hydrate | Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 157212-55-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013A. | |
| Bosentan hydrate | Bosentan inhibits the presser response to big ET-1 both after i.v. and oral administration, with a long duration of action and no intrinsic agonist activity. Synonyms: Ro 47-0203; Ro 470203; Ro470203; Ro-470203. Grade: >98%. CAS No. 157212-55-0. Molecular formula: C27H29N5O6S.H2O. Mole weight: 569.63. | |
| Bosentan Hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. Alternative Names: Bosentan monohydrate,Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-, hydrate (1:1), Bosentan hydrate, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-, monohydrate (9CI). | |
| Bosentan Hydrate | Bosentan Hydrate. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide Hydrate (1:1). Grades: Highly Purified. CAS No. 157212-55-0. Pack Sizes: 25mg. Molecular Formula: C27H31N5O7S, Molecular Weight: 569.63. US Biological Life Sciences. | Worldwide |
| Bosentan impurity 1 | Bosentan impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1065472-77-6. Molecular formula: C27H25D4N5O6S. Mole weight: 555.64. Catalog: APB1065472776. | |
| Bosentan Impurity 1 | Bosentan Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.17. Catalog: APB150728135. | |
| Bosentan Impurity 3 | Bosentan Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butyl)-N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.01. Catalog: APB150727063. | |
| Bosentan Impurity D | Bosentan Impurity D is an impurity of Bosentan. Synonyms: O-Deshydroxyethyl Bosentan; N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide; 4-tert-Butyl-N-[6-hydroxy-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide. Grade: > 95%. CAS No. 174227-14-6. Molecular formula: C25H25N5O5S. Mole weight: 507.57. | |
| Bosentan Related Compound 1 | Bosentan Related Compound 1 is an exquisite biomedical concoction used in the research of the complex ailment known as pulmonary arterial hypertension. Functioning as a highly discerning antagonist of the endothelin receptor, it proficiently curbs the constriction. Synonyms: 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine; Bosentan Related Compound D; 4,6-Dichloro-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)pyrimidine; Bosentan Related Compound D USP. Grade: > 95%. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.18. | |
| Bosentan Related Compound 2 | Bosentan Related Compound 2 is an intermediate as well as a degradation impurity of the endothelin receptor antagonist Bosentan. Synonyms: 4-tert-Butylbenzenesulfonamide; 4-(1,1-Dimethylethyl)benzenesulfonamide; p-tert-butyl-Benzenesulfonamide; NSC 9911. Grade: > 95%. CAS No. 6292-59-7. Molecular formula: C10H15NO2S. Mole weight: 213.30. | |
| Bosentan Related Compound 3 | Bosentan Related Compound 3 is an intermediate of Bosentan. Synonyms: N-[6-Chloro-5-(2-methoxyphenoxy)-(2,2-bipyrimidine)4-4-yl]-(1,1-dimethylethyl)-benzenesulfonamide; 4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzeneSulfonamide. Grade: > 95%. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.02. | |
| Bosentan Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound C | Bosentan Related Compound C is an impurity of Bosentan. Synonyms: N,N'-[1,2-Ethanediylbis[oxy[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-6,4-diyl]]]bis[4-(1,1-dimethylethyl)-benzenesulfonamide; 1,2-Bis({6-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl}oxy)ethane; Bosentan dimer. Grade: > 95%. CAS No. 1097263-60-9. Molecular formula: C52H52N10O10S2. Mole weight: 1041.18. | |
| Bosentan Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound D | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound E | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Desmethyl bosentan | Desmethyl bosentan. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; Ro 47-8634. Grades: Highly Purified. CAS No. 253688-61-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C26H27N5O6S. US Biological Life Sciences. | Worldwide |
| Desmethyl Bosentan | Desmethyl Bosentan is a metabolite of Bosentan. Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; Ro 47-8634. Grade: > 95%. CAS No. 253688-61-8. Molecular formula: C26H27N5O6S. Mole weight: 537.60. | |
| Desmethyl Bosentan (4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide) | A metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 253688-61-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Desmethyl Bosentan-d4 | Desmethyl Bosentan-d4. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide-d4; Ro 47-8634. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C26H23D4N5O6S, Molecular Weight: 541.61. US Biological Life Sciences. | Worldwide |
| Hydroxy bosentan | Hydroxy bosentan. Group: Biochemicals. Alternative Names: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634; Ro 48-5033. Grades: Highly Purified. CAS No. 253688-60-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H29N5O7S. US Biological Life Sciences. | Worldwide |
| Hydroxy Bosentan | Hydroxy Bosentan is a metabolite of Bosentan. Synonyms: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634; Ro 48-5033. Grade: > 95%. CAS No. 253688-60-7. Molecular formula: C27H29N5O7S. Mole weight: 567.63. | |
| Hydroxy Bosentan-d4 | A labeled analogue of the active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d4; Ro 48-5033-d4. Grades: Highly Purified. CAS No. 1065472-91-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Hydroxy Bosentan-[d4] | Hydroxy Bosentan-[d4] is the labelled analogue of Hydroxy Bosentan, which is the active metabolite of Bosentan. Bosentan is an endothelin receptor antagonist used in the treatment of pulmonary artery hypertension (PAH). Synonyms: Hydroxy Bosentan D4; 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d4; Ro 48-5033-d4. Grade: >95%. CAS No. 1065472-91-4. Molecular formula: C27H25D4N5O7S. Mole weight: 571.65. | |
| Hydroxy Bosentan-[d6] | Hydroxy Bosentan-[d6] is the labelled analogue of Hydroxy Bosentan, which is the active metabolite of Bosentan. Bosentan is an endothelin receptor antagonist used in the treatment of pulmonary artery hypertension (PAH). Synonyms: Hydroxy Bosentan D6; 4-[2-Hydroxy-1,1-(dimethyl-d6)ethyl]-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d6; Ro 48-5033-d6. Grade: >95%. CAS No. 1246817-57-1. Molecular formula: C27H23D6N5O7S. Mole weight: 573.66. | |
| Hydroxy Bosentan (Ro 48-5033) | A metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Group: Biochemicals. Alternative Names: Ro 48-5033. Grades: Highly Purified. CAS No. 253688-60-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Hydroxy Desmethyl Bosentan | A metabolite of Bosentan. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Hydroxy Desmethyl Bosentan-d4 | Hydroxy Desmethyl Bosentan-d4. Group: Biochemicals. Alternative Names: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine-D4 | 4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine-D4 is a labelled version of 4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine. 4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine is an impurity of Bosentan. Synonyms: Bosentan Impurity-D4. Molecular formula: C21H19D4ClN4O4. Mole weight: 434.91. | |
| N-[6-Chloro-5-(2-methoxyphenoxy)-(2,2-bipyrimidine)4-4-yl]-(1,1-dimethylethyl)-benzenesulfonamide | An intermediate of Bosentan, which is a mixed endothelin receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nebentan potassium | Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ET A receptor antagonist through the modification of Bosentan (HY-A0013). Nebentan potassium inhibits [ 125 I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with K i of 0.697 nM and 569 nM, respectively [1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM598. CAS No. 342005-82-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106994A. | |
| Tezosentan-[d4] | Tezosentan-[d4] is the labelled analogue of Tezosentan, which is a potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan used as a vasodilator. Synonyms: Tezosentan D4; N-[6-(2-Hydroxyethoxy-d4)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-(1-methylethyl)-2-pyridinesulfonamide. CAS No. 1794707-10-0. Molecular formula: C27H23D4N9O6S. Mole weight: 609.65. | |
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