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Intermediate in the synthesis of Acylfulvene derivative antitumor agents. Group: Biochemicals. Alternative Names: 1-[1-[-2-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-1-hydroxy-1-methyl-4- (trimethylsilyl) -3-butynyl]cyclopropyl]-ethanone. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
1-(2,3,4,6-Tetrakis-O-benzyl)-2,3-bis(tert-butyldimethylsilyloxy) KRN7000 is a strong agonist for Natural Killer T cells. Mostly utilized to facilitate immunotherapy research, it has been associated with autoimmune diseases and certain cancers. Uses: Intermediate for the preparation of krn7000. Synonyms: N- [ (1S, 2S, 3R) -2, 3-Bis [ [ (1, 1-dimethylethyl) dimethylsilyl] oxy] -1- [ [ [2, 3, 4, 6-tetrakis-O- (phenylmethyl) -α -D-galactopyranosyl] oxy] methyl] heptadecyl] hexacosanamide. CAS No. 205371-69-3. Molecular formula: C90H151NO9Si2. Mole weight: 1447.33.
1-((2R,3R,4R)-4-((tert-butyldimethylsilyl)oxy)-3-fluoro-5,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a chemical compound of potential interest in biomedical research, has been studied for its therapeutic benefits against various diseases. Research shows promising antiviral properties against viral infections such as HIV and the capacity to inhibit cancer cell proliferation enzymes, making it a potential candidate for cancer treatment. However, further investigation is necessary to comprehend its full range of therapeutic uses. Synonyms: 1-((2R,3R,4R)-4-((tert-butyldimethylsilyl)oxy)-3-fluoro-5,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-[(2R,3R,4R)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-5,5-bis(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; C16H27FN2O6Si; DTXSID101126509; CS-M3506; VHC37961; AKOS037650615; CS-15069; C13027; 2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-4'-C-(hydroxymethyl)uridine. Grades: 98%. CAS No. 1445379-61-2. Molecular formula: C16H27FN2O6Si. Mole weight: 390.48.
1,3-O-Benzylidene-4-O-t-butyl-dimethylsilyl-D-threitol, a versatile compound with chiral structures, holds significant potential in the realm of carbohydrate-based drugs and therapies. This compound's distinctive molecular composition allows it to serve as a valuable chiral building block for synthesizing complex carbohydrates and glycoconjugates, which exhibit an array of potential biomedical applications. From targeting drug delivery to personalized immunotherapy, this compound's multifaceted nature offers a vital tool in biomedicine research. As such, it has garnered significant attention for its unique properties in diverse fields, including cancer, diabetes, and viral infections. CAS No. 652979-92-5. Molecular formula: C17H28O4Si. Mole weight: 324.49.
Intermediate in the preparation of Testosterone metabolties. Group: Biochemicals. Alternative Names: 17-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-5, 14-androstadiene-3 β,17 β-diol. Grades: Highly Purified. CAS No. 61252-32-2. Pack Sizes: 10mg. US Biological Life Sciences.
2',3',5'-Tri-O-(t-butyldimethylsilyl)-4'-C-hydroxymethyluridine is a highly modified nucleoside characterized by its frequent use in RNA synthesis. Acting as a substrate for RNA polymerases, its presence ensures the efficient addition of other nucleotides, ultimately leading to the formation of RNA target sequences. This unique compound also has the added benefit of offering insight into the effects of nucleoside modifications on RNA's biological structure and function. Synonyms: 2',3',5'-Tris-O-[(1,1-dimethylethyl)dimethylsilyl]-4'-C-(hydroxymethyl)-Uridine; 1-{2,3-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]-4-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-α-L-lyxofuranosyl}-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 232588-97-5. Molecular formula: C28H56N2O7Si3. Mole weight: 617.01.
2',3'-Bis-(O-t-butyldimethylsilyl)uridine
2',3'-Bis-(O-t-butyldimethylsilyl)uridine, a widely utilized compound in the realm of biomedicine, assumes an indispensable function in the amalgamation of nucleoside analogs and antiviral pharmaceuticals, notably AZT and acyclovir. Moreover, it exerts an inhibitory effect on viral replication, rendering it instrumental in combating illnesses such as HIV and herpes. Its exceptional attributes render this biomedical research and drug development tool truly invaluable. Synonyms: Uridine, 2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2',3'-Bis-O-tert-butyldimethylsilyluridine; 1-[(2R,3R,4R,5R)-3,4-bis[[tert-butyl(dimethyl)silyl]oxy]-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 2'-O,3'-O-Bis(tert-butyldimethylsilyl)uridine; 2',3'-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine. Grades: ≥95%. CAS No. 69504-12-7. Molecular formula: C21H40N2O6Si2. Mole weight: 472.72.
2',3'-Di-O-(tert-butyldimethylsilyl)-2'-deoxycytidine is an intermediate for biosynthesis of cholyl-CoA and oligodeoxyribonucleoti de s. Group: Biochemicals. Alternative Names: 3',5'-Bis-O-tert-butyldimethylsilyl-2'-deoxycytidine; 2'-Deoxy-3', 5'-bis-O- [ (1, 1-dimethylethyl) dimethylsilyl] cytidine. Grades: Highly Purified. CAS No. 51549-29-2. Pack Sizes: 1g. US Biological Life Sciences.
2',3'-Di-O-(tert-butyldimethylsilyl)-2'-deoxycytidine is an intermediate for biosynthesis of cholyl-CoA and oligodeoxyribonucleotides. Synonyms: 3',5'-Bis-O-tert-butyldimethylsilyl-2'-deoxycytidine; 2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine. CAS No. 51549-29-2. Molecular formula: C21H41N3O4Si2. Mole weight: 455.74.
It is used for nucleoside modification and nucleic acid synthesis. Synonyms: 2'-O-TBDMS-5'-O-DMT-N4-Ac cytidine; N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine; N4-acetyl-2'-O-(t-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)cytidine; 5'-O-(4,4'-Dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl]-N4-acetylcytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine. Grades: ≥95%. CAS No. 121058-85-3. Molecular formula: C38H47N3O8Si. Mole weight: 701.88.
A protected potential anti-cancer and anti-viral agent. Uses: A protected potential anti-cancer and anti-viral agent. Synonyms: 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-5'-O-(triphenylmethyl)uridine 3'-(O-Phenyl carbonothioate). Grades: 95%. CAS No. 130860-11-6. Molecular formula: C41H44N2O7SSi. Mole weight: 736.95.
2'-O-tert-Butyldimethylsilyl-5-methyluridine
2'-O-tert-Butyldimethylsilyl-5-methyluridine standing as an essential entity wielded within the biomedical realm to orchestrate the research and development of nucleoside analogs. Rendering itself instrumental in crafting antiviral medications and providing a foundational cornerstone for tackling an assortment of viral afflictions, this compound exhibiting indomitably consequential characteristics that have propelled it towards the forefront of pharmaceutical research and development. Synonyms: 2'-TBDMS-5-Me-rU; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-5-methyluridine; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-5-methyluridine. Grades: ≥97% by HPLC. CAS No. 922508-26-7. Molecular formula: C16H28N2O6Si. Mole weight: 372.49.
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
It is used for RNA synthesis and special nucleoside modification. Synonyms: 5'-O-DMT-2'-O-TBDMS adenosine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-t-butyldimethylsilyl adenosine; (2R, 3R, 4R, 5R) -5- (6-Amino-9H-purin-9-yl) -2- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( (tert-butyldimethylsilyl) oxy) tetrahydrofuran-3-ol; 5'-O-[Bis (4-methoxyphenyl) phenylmethyl]-2'-O-[ (1, 1-dimethylethyl) dimethylsilyl]adenosine. Grades: ≥95%. CAS No. 81794-13-0. Molecular formula: C37H45N5O6Si. Mole weight: 683.87.
2'-O-Tert-butyldimethylsilyl-5'-O-DMT-uridine
It is used for RNA synthesis and special nucleoside modification. Synonyms: 5'-O-DMT-2'-O-TBDMS uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-t-butyldimethylsilyl uridine; 1- ( (2R, 3R, 4R, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3- ( (tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2, 4 (1H, 3H)-dione; 2'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)uridine; 5'-O-(4,4'-Dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl]-uridine. Grades: ≥95%. CAS No. 81246-80-2. Molecular formula: C36H44N2O8Si. Mole weight: 660.83.
2'-O-(tert-Butyldimethylsilyl)-5'-O-trityluridine
A protected potential anti-cancer and anti-viral agent. Uses: A protected potential anti-cancer and anti-viral agent. Synonyms: 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-5'-O-(triphenylmethyl)urdine. Grades: 95%. CAS No. 117136-35-3. Molecular formula: C34H40N2O6Si. Mole weight: 600.78.
2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine
2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine. Group: Biochemicals. Alternative Names: 2'-O-[ (1, 1-Dimethylethyl) dimethylsilyl]-5'-O- (triphenylmethyl) urdine. Grades: Highly Purified. CAS No. 117136-35-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C34H40N2O6Si. US Biological Life Sciences.
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2-O-tert-Butyldimethylsilyl-6,7-O-(1-methylethylene)-monic Acid A Methyl Ester
2-O-tert-Butyldimethylsilyl-6,7-O-(1-methylethylene)-monic Acid A Methyl Ester is an intermediate in the preparation of Monic Acid (M520500) and Mupirocin F. Group: Biochemicals. Alternative Names: 5, 9-Anhydro-2, 3, 4, 8-tetradeoxy-8-[[ (2S, 3S) -3-[ (1R, 2S) -2-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-6, 7-O- (1-methylethylidene) -L-talo-non-2-enonic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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2-O-tert-Butyldimethylsilyl-6,7-O-(1-methylethylene)-monic Acid A Methyl Ester
2-O-tert-Butyldimethylsilyl-6,7-O-(1-methylethylene)-monic Acid A Methyl Ester is an intermediate of Mupirocin, which is a carboxylic acid bacteriostatic/bactericidal antibiotic. Synonyms: 5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1R,2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-6,7-O-(1-methylethylidene)-L-talo-non-2-enonic Acid Methyl Ester; L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1R,2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-6,7-O-(1-methylethylidene)-, methyl ester, (2E)-. Grades: ≥95%. CAS No. 1314406-71-7. Molecular formula: C27H48O7Si. Mole weight: 512.75.
2'-O-tert-Butyldimethylsilyladenosine
2'-O-tert-Butyldimethylsilyladenosine, a remarkable pharmaceutical compound found in the field of biomedicine, stands as an extraordinary weapon in the relentless fight against viral invasions. Unleashing its unparalleled antiviral prowess, it meticulously sabotages viral replication processes, emerging triumphant against an array of treacherous viruses. This unparalleled marvel strategically disrupts viral RNA synthesis, casting a long shadow over notorious viral diseases, including the persistent influenza and the formidable hepatitis C. Synonyms: Adenosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-((tert-butyldimethylsilyl)oxy)-2-(hydroxymethyl)tetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[tert-butyl(dimethyl)silyl]oxy-2-(hydroxymethyl)oxolan-3-ol; 2'-o-tert-butyldimethylsilyladenosine;2'-O-[tert-Butyl(dimethyl)silyl]adenosine. CAS No. 69504-13-8. Molecular formula: C16H27N5O4Si. Mole weight: 381.5.
2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine, a vital reagent in the biomedical sector, holds immense significance for synthesizing diverse antiviral medications. Its unparalleled structure and mechanism of action contribute significantly to combating viral infections like hepatitis C and HIV. Synonyms: 2'-TBDMS-ibu-rG; 2'-O-(tert-Butyldimethylsilyl)-N-isobutyrylguanosine; Guanosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine. Grades: 96%. CAS No. 182007-86-9. Molecular formula: C20H33N5O6Si. Mole weight: 467.59.
2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine
2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine is a complex and multifunctional nucleoside analog extensively used in pharmaceutical applications to counter cytidine-sensitive viruses, including hepatitis B and C infections. The compound serves as a significant precursor for the synthesis of modified RNA-based therapies that have promising curative effects for genetic disorders and cancer treatments. Its diverse chemical properties make it an essential and indispensable agent for investigating various antiviral mechanisms that could pave the way for novel and innovative drug discovery. Synonyms: 2'-TBDMS-Bz-rC; N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-. Grades: ≥97% by HPLC. CAS No. 185398-21-4. Molecular formula: C22H31N3O6Si. Mole weight: 461.58.
2'-O-tert-Butyldimethylsilyluridine
2'-O-tert-Butyldimethylsilyluridine, an indispensable compound within the biomedical field, serves as a pivotal synthetic intermediate for nucleoside analogues. Notably, it assumes a vital function in the production of antiviral medications, specifically targeting the eradication of hepatitis B and C viral infections. Given its distinct structural and inherent characteristics, this compound assumes an indispensable role in the intricate processes of drug discovery and development. Synonyms: 2'-TBDMS-rU; Uridine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]uridine. Grades: ≥97% by HPLC. CAS No. 54925-71-2. Molecular formula: C15H26N2O6Si. Mole weight: 358.46.
A reactant used in the preparation of macrocyclic carboxylic acids, amides, and acylsulfonamides as inhibitors of HCV replication. Group: Biochemicals. Alternative Names: (2S) -2- [ [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] methyl] -4-ethylidene-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Intermediate in the synthesis of (2S,3R)-3-Methylglutamic Acid, an agonist for kainate receptors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Intermediate in the synthesis of (2S,3R)-3-Methylglutamic Acid, an agonist for kainate receptors. Group: Biochemicals. Alternative Names: (2S) -2- [ [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] methyl] -2, 5-dihydro-5-oxo-1H-pyrrole-1-carboxylic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 81658-27-7. Pack Sizes: 50mg. US Biological Life Sciences.
2-tert-Butyldimethylsilyloxy-1,1-dimethylethylamine is an intermediate in the synthesis of Timolol (T443705), an antihypertensive agent. Group: Biochemicals. Alternative Names: 1- [ [tert-Butyldimethylsilyl] oxy] -2-methylpropan-2-amine; 1-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-2-methyl-2-propanamine. Grades: Highly Purified. CAS No. 117460-98-7. Pack Sizes: 1g. US Biological Life Sciences.
A reactant used in the preparation of Methyl-D-erythritol Phosphate, a substrate in terpenoid biosynthesis. Group: Biochemicals. Alternative Names: [[[ (2Z) -4-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-2-methyl-2-buten-1-yl]oxy]methyl]-benzene. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Byproduct formed during the preparation of Testosterone metabolites. Group: Biochemicals. Alternative Names: 3, 17-Bis-O-[ (1, 1-Dimethylethyl) dimethylsilyl]-5, 14-androstadiene-3 β,17 β-diol. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
3,4,6-Tri-O-(tert-butyldimethylsilyl)-D-glucal is a vital compound in the biomedical industry commonly used as a reactant in the research and development of various drugs targeting diabetes, cancer, and cardiovascular diseases. Its unique structure and properties make it a versatile intermediate for pharmaceutical research and development. Synonyms: 1,5-Anhydro-2-deoxy-3,4,6-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-D-arabino-hex-1-enitol. CAS No. 79999-47-6. Molecular formula: C24H52O4Si3. Mole weight: 488.92.
3',5'-Bis-O-(t-butyldimethylsilyl)thymidine
3',5'-Bis-O-(t-butyldimethylsilyl)thymidine is a crucial compound in compound used as a precursor for synthesizing modified DNA for research purposes. It's utilized in the development of nucleoside analogs and nucleotide derivatives, aiding in the investigation of DNA functions and various diseases, including cancer, viral infections, and genetic disorders. Synonyms: 3', 5'-Bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]thymidine; 3'-O,5'-O-Bis(tert-butyldimethylsilyl)thymidine; 1- ( (2R, 4S, 5R) -4- (tert-butyldimethylsilyloxy) -5- ( (tert-butyldimethylsilyloxy) methyl) tetrahydrofuran-2-yl) -5-methylpyrimidine-2, 4 (1H, 3H) -dione; 3',5'-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]thymidine. Grades: ≥95%. CAS No. 40733-26-4. Molecular formula: C22H42N2O5Si2. Mole weight: 470.75.
An intermediate in the preparation of cytidine derivatives. Uses: An intermediate in the preparation of cytidine derivatives. Synonyms: 2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]uridine. CAS No. 64911-18-8. Molecular formula: C21H40N2O5Si2. Mole weight: 456.72.
An intermediate in the preparation of cytidine derivatives. Group: Biochemicals. Alternative Names: 2'-Deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]uridine. Grades: Highly Purified. CAS No. 64911-18-8. Pack Sizes: 50mg. US Biological Life Sciences.
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