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The enzyme from Clostridium sp. also acts, more slowly, on pentanoate and propanoate, and on some branched-chain fatty acids (cf. EC 2.7.1.14 sedoheptulokinase). Group: Enzymes. Enzyme Commission Number: EC 2.7.2.7. CAS No. 37278-14-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3178; butyrate kinase; EC 2.7.2.7; 37278-14-1. Cat No: EXWM-3178.
branched-chain-fatty-acid kinase
3-Methylbutanoate, 2-methylbutanoate, pentanoate, butanoate and propanoate can also act as acceptors (cf. EC 2.7.2.7 butyrate kinase). Group: Enzymes. Synonyms: isobutyrate kinase. Enzyme Commission Number: EC 2.7.2.14. CAS No. 84177-54-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3172; branched-chain-fatty-acid kinase; EC 2.7.2.14; 84177-54-8; isobutyrate kinase. Cat No: EXWM-3172.
In molecular biology, acetate kinase (EC 2.7.2.1), which is predominantly found in micro-organisms, facilitates the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation. Short-chain fatty acids (SCFAs) play a major role in carbon cycle and can be utilized as a source of carbon and energy by bacteria. The enzyme is important in the process of glycolysis, enzyme levels being increased in the presence of excess glucose. The growth of a bacterial mutant lacking acetate kinase has been shown to be inhibited by glucose, suggesting that the enzyme is involved in excretion of excess carbohydRate. A related enzyme, butyRate kinase. acetate kinase from creative enzymes. this [32p]-acetyl phosphate was used to label bldm, bldm d-54n or bldm d-54a loci during the study of the effect of bldm gene on streptomyces coelicolor development. Group: Enzymes. Synonyms: Acetate kinase (phosphorylating); Acetic kinase; Acetokinase; EC 2.7.2.1; 9027-42-3; Acetate kinase. Enzyme Commission Number: EC 2.7.2.1. CAS No. 9027-42-3. Acetate kinase. Activity: 400-1,200 units/mg solid. Storage: 2-8°C. Form: lyophilized powder. Contains potassium phosphate buffer. Source: Bacillus stearothermophilus. Acetate kinase (phosphorylating); Acetic kinase; Acetokinase; EC 2.7.2.1; 9027-42-3; Acetate kinase. Cat No: NATE-0016.
Native Escherichia coli Acetate Kinase
In molecular biology, acetate kinase (EC 2.7.2.1), which is predominantly found in micro-organisms, facilitates the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation. Short-chain fatty acids (SCFAs) play a major role in carbon cycle and can be utilized as a source of carbon and energy by bacteria. The enzyme is important in the process of glycolysis, enzyme levels being increased in the presence of excess glucose. The growth of a bacterial mutant lacking acetate kinase has been shown to be inhibited by glucose, suggesting that the enzyme is involved in excretion of excess carbohydRate. A related enzyme, butyRate kinase, facili.rom escherichia coli has been used as part of an atp-regenerating system to study the kinetics of agonist-stimulated transphosphatidylatio. Group: Enzymes. Synonyms: Acetate kinase (phosphorylating); Acetic kinase; Acetokinase; AK; EC 2.7.2.1; 9027-42-3; Acetate kinase. Enzyme Commission Number: EC 2.7.2.1. CAS No. 9027-42-3. Acetate kinase. Activity: > 150 units/mg protein (biuret). Storage: -20°C. Form: Lyophilized powder containing trehalose with small amounts of potassium phosphate, magnesium chloride, and dithiothreitol. Source: Escherichia coli. Acetate kinase (phosphorylating); Acetic kinase; Acetokinase; AK; EC 2.7.2.1; 9027-42-3; Acetate kinase. Cat No: NATE-0017.
Sodium Butyrate
A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells. Group: Biochemicals. Alternative Names: Butanoic Acid Sodium Salt; Butyric acid Sodium Salt; Adimix; Butyrate Sodium; Gustor XXI B 70; Sodium Butanoate. Grades: Highly Purified. CAS No. 156-54-7. Pack Sizes: 250g, 500g, 1Kg. Molecular Formula: C?H?NaO?, Molecular Weight: 110.09. US Biological Life Sciences.
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1-(3-Chloropropoxy)-4-fluorobenzene
1-(3-Chloropropoxy)-4-fluorobenzene was used as a reagent in the preparation of a library of hydantoin compds which has used to study Aurora kinase A inhibitory activity. It was also used as an alkylation agent in the preparation of tetracyclic quinoxaline butyrophenones as 5-HT2A and postsynaptic D2 antagonists and inhibitors of serotonin transporter for treatment of neuropsychiatric and neurological disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 1716-42-3. Pack Sizes: 1g, 5g. Molecular Formula: C9H10ClFO, Molecular Weight: 188.63. US Biological Life Sciences.
Worldwide
ACG548B
ACG548B is a potent inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50s of 1.78 and 0.496 μM, respectively. It has higher AChE affinity and selectivity over BChE and ChoK (choline kinase). Synonyms: ACG-548B; 1,1'-([1,1'-biphenyl]-3,3'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)pyridin-1-ium) bromide. CAS No. 795316-16-4. Molecular formula: C38H34Br2Cl2N4. Mole weight: 777.42.
Butyrolactone I
Butyrolactone I is an exogenous inhibitor of CDK cyclin-dependent kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 87414-49-1. Pack Sizes: 200ug, 400ug. Molecular Formula: C24H24O7, Molecular Weight: 424.44. US Biological Life Sciences.
Worldwide
Butyrolactone I
It is one of a family of three butyrolactones isolated from aspergillus fumigatus. It exhibits antitumor activity and inhibits the cell cycle at the G1/S and G2/M transitions. It is a selective inhibitor of cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Synonyms: Olomoucin; 4'-O-Demethylversicolactone D; (2R)-2,5-Dihydro-4-hydroxy-2-[[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxo-2-furancarboxylic Acid Methyl Ester; (+)-3''-Dimethylallyl-butyrolactone II. Grade: >95% by HPLC. CAS No. 87414-49-1. Molecular formula: C24H24O7. Mole weight: 424.44.
Butyrolactone I - CAS 87414-49-1
A cell-permeable and highly selective inhibitor of cyclin-dependent protein kinases (Cdks) that inhibits cell cycle progression at the G?/S and G?/M transitions. Group: Fluorescence/luminescence spectroscopy.
CMPD-1
CMPD-1, also called MK2a Inhibitor, inhibits tubulin polymerisation. It inhibit p38α-mediated MK2a phosphorylation (apparent Ki = 330 nM). Synonyms: CMPD1; CMPD-1; CMPD 1; IN1225; IN-1225; IN 1225; 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; MK2a Inhibitor; MAPKAPK2a Inhibitor; CMPD1; CHEMBL235658; 41179-33-3; IN1225; 4-(2' -Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor_x000D_; SCHEMBL169905. CAS No. 41179-33-3. Molecular formula: C22H20FNO2. Mole weight: 349.4.
A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 156-54-7. Pack Sizes: 10ml, 25ml, 50ml. Molecular Formula: C?H?NaO?, Molecular Weight: 110.09. US Biological Life Sciences.
A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 156-54-7. Pack Sizes: 10ml, 25ml, 50ml. Molecular Formula: C?H?NaO?, Molecular Weight: 110.09. US Biological Life Sciences.
Worldwide
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