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| Product | Description | |
|---|---|---|
| C2 Ceramide | C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis , inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ceramide 2. CAS No. 3102-57-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101180. |  |
| c2 Ceramide-1-phosphate | c2 Ceramide-1-phosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: C2 Ceramide-1-phosphate;N-Acetylsphingosine-1-phosphate;N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecenyl]Acetamide. Product Category: Heterocyclic Organic Compound. CAS No. 151729-55-4. Molecular formula: C20H40NO6P. Mole weight: 421.508462 [g/mol]. Purity: 0.96. IUPACName: [(2S,3R)-2-acetamido-3-hydroxyoctadec-4-enyl] dihydrogen phosphate. Canonical SMILES: CCCCCCCCCCCCCC=CC(C(COP(=O)(O)O)NC(=O)C)O. Product ID: ACM151729554. Alfa Chemistry ISO 9001:2015 Certified. |  |
| C2 ceramide-1-phosphate | C2 ceramide-1-phosphate. Group: Biochemicals. Alternative Names: N- [ (1S, 2R, 3E) -2-Hydroxy-1- [ (phosphonooxy) methyl] -3-heptadecenyl] acetamide; N-Acetylsphingosine-1-phosphate. Grades: Highly Purified. CAS No. 151729-55-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C20H40NO6P. US Biological Life Sciences. |  Worldwide |
| C2 Ceramide-1-phosphate (N-Acetylsphingosine-1-phosphate) | Ceramide-1-phosphate blocks apoptosis through inhibition of acid sphingomyelinase in macrophages. Group: Biochemicals. Alternative Names: N-Acetylsphingosine-1-phosphate. Grades: Highly Purified. CAS No. 151729-55-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| C2 Ceramide (N-Acetyl-D-sphingosine, Acetyl Ceramide) | A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; N-Acetyl-D-sphingosine; Acetyl Ceramide; N-Acetylsphingosine. Grades: Highly Purified. CAS No. 3102-57-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??NO?, Molecular Weight: 341.53. US Biological Life Sciences. | Worldwide |
| 1-O-Benzoyl C2 Ceramide | C2 Ceramide derivative. Group: Biochemicals. Alternative Names: 1-O-benzoyl-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; 1-O-benzoyl-N-acetyl-D-sphingosine; 1-O-benzoyl Acetyl Ceramide; 1-O-benzoyl N-Acetylsphingosine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 2-O-tert-Butyldimethylsilyl-1-O-benzoyl C2 Ceramide | C2 Ceramide derivative. Group: Biochemicals. Alternative Names: 2-O-tert-Butyldimethylsilyl-1-O-benzoyl-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; 2-O-tert-Butyldimethylsilyl-1-O-benzoyl-N-acetyl-D-sphingosine; 2-O-tert-Butyldimethylsilyl-1-O-benzoyl Acetyl Ceramide; 2-O-tert-Butyldimethylsilyl-1-O-benzoyl N-Acetylsphingosine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 2-O-tert-Butyldimethylsilyl C2 Ceramide-1-(bis(2-cyanoethyl)phosphate | C2 Ceramide derivative. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| c20 Ceramide | c20 Ceramide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-Eicosanoylsphingosine; N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]Eicosanamide; (E)-D-erythro- N-[2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]Eicosanamide; [R-[R*,S*-(E)]]-N-[2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]Eicosanamide; N-(Eicosanoyl)-D-erythro-1,3-dihydroxy-2-amino-4-trans-octadecene; N-(Eicosanoyl)sphingosine; N-Eicosanoyl-C18-sphingosine. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 7344-2-7. Molecular formula: C38H75NO3. Mole weight: 594.01. Product ID: ACM7344027. Alfa Chemistry ISO 9001:2015 Certified. | |
| C20 Ceramide | C20 Ceramide is a natural 20:0 ceramide that is abundant in the brain [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Arachidoyl-D-sphingosine. CAS No. 7344-2-7. Pack Sizes: 1 mg. Product ID: HY-112016. | |
| C20-Ceramide | C20-Ceramide. Group: Biochemicals. Alternative Names: N-Eicosanoylsphingosine; N- [ (1S, 2R, 3E) -2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] eicosanamide; (E)-D-erythro- N- [2-hydroxy-1- (hydroxymethyl) -3-heptadecenyl] eicosanamide. Grades: Highly Purified. CAS No. 7344-2-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C38H75NO3. US Biological Life Sciences. | Worldwide |
| C20 Ceramide (N-Eicosanoylsphingosine) | C20 Ceramide (N-Eicosanoylsphingosine) . Group: Biochemicals. Alternative Names: N-Eicosanoylsphingosine. Grades: Highly Purified. CAS No. 7344-2-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| C22-Ceramide | C22-Ceramide (Cer d18:1/22:0) is an endogenous bioactive sphingolipid. C22-Ceramide reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Behenoyl-D-erythro-sphingosine; Cer d18:1/22:0. CAS No. 27888-44-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154831. | |
| C22-Ceramide | C22-Ceramide. Group: Biochemicals. Alternative Names: N-[(3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-docosanamide. Grades: Highly Purified. CAS No. 869501-30-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C40H79NO3. US Biological Life Sciences. | Worldwide |
| C22 Ceramide (d14:1/22:0) | C22 Ceramide (d14:1/22:0). Group: Others. Purity: >99%. Mole weight: 565.954. Stability: 1 Year. Storage: -20°C. C22 Ceramide (d14:1/22:0); N-behenoyl-D-erythro-sphingosine (C14 base). Cat No: SPHZ-145. |  |
| C22 Ceramide (N-[(3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-docosanamide) | C22 Ceramide (N-[(3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-docosanamide). Group: Biochemicals. Alternative Names: N-[(3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-docosanamide. Grades: Highly Purified. CAS No. 869501-30-4. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| C24:1 b-D-Galactosyl ceramide | C24:1 b-D-Galactosyl ceramide is a renowned compound prevalent in the ever-evolving biomedical realm, specifically tailored for the research of diverse afflictions, including Gaucher disease and Fabry disease. Synonyms: Galactosyl-b-1,1 N-nervonoyl-D-erythro-sphingosine. Grades: >99%. CAS No. 17283-91-9. Molecular formula: C48H91NO8. Mole weight: 810.24. |  |
| C24:1Ceramide | C24:1Ceramide. Group: Biochemicals. Alternative Names: Nervonic ceramide. Grades: Highly Purified. CAS No. 54165-50-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C42H81NO3. US Biological Life Sciences. | Worldwide |
| C24:1-Ceramide | C24:1-Ceramide is one of the most abundant naturally occurring ceramide. Ceramides regulates many diverse biological activities, such as cell apoptosis , cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54164-50-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134575. | |
| C24:1 Ceramide (Nervonic Ceramide) | Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of phospholipase C, appropriately named sphingomyelinase. Group: Biochemicals. Alternative Names: Nervonic Ceramide. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| C24:1 Galactosyl(α) Ceramide (d18:1/24:1(15Z)) | C24:1 Galactosyl(α) Ceramide (d18:1/24:1(15Z)). Group: Others. Synonyms: C24:1 α-D-galactosyl ceramide; N-(15Z-tetracosenoyl)-1-α-galactosyl-sphing-4-enine. Purity: >99%. Mole weight: 810.238. Stability: 6 Months. C24:1 α-D-galactosyl ceramide; N-(15Z-tetracosenoyl)-1-α-galactosyl-sphing-4-enine; C24:1 Galactosyl(α) Ceramide (d18:1/24:1(15Z)); D-galactosyl- α-1,1' N-nervonoyl-D-erythro-sphingosine. Cat No: SPHZ-073. | |
| C24:1 Mono-sulfo galactosyl (alpha) ceramide (d18:1/24:1) Ammonium salt | C24:1 Mono-sulfo galactosyl (alpha) ceramide (d18:1/24:1) Ammonium salt is a valuable compound serving as a formidable biomarker facilitating the comprehensive investigation of ceramide involvement in diverse pathological conditions, spanning from malignancies such as cancer, to metabolic disorders like diabetes is and even neurodegenerative ailments. Synonyms: 3-O-Sulfo-D-galactosyl-alpha-1,1'-N-Nervonoyl-D-erythro-sphingsoine (ammonium salt); 3-O-sulfo-alpha-D-C24:1-galactosylceramide (ammonium salt); ammonium (2S,3R,4S,5S,6R)-3,5-dihydroxy-2-(((2S,3R,E)-3-hydroxy-2-((Z)-tetracos-15-enamido)octadec-4-en-1-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl sulfate; Ammonium (2S,3R,4E)-3-hydroxy-2-[(15Z)-15-tetracosenoylamino]-4-octadecen-1-yl 3-O-sulfonato-α-D-threo-hexopyranoside. Grades: >99%. CAS No. 2260670-38-8. Molecular formula: C48H94N2O11S. Mole weight: 907.33. | |
| C24-Ceramide | C24-Ceramide. Group: Biochemicals. Alternative Names: Lignoceric ceramide. Grades: Highly Purified. CAS No. 34435-05-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C42H83NO3. US Biological Life Sciences. | Worldwide |
| C24-Ceramide (d18:1/24:0) | C24-Ceramide (d18:1/24:0) is a sphingolipid that can be used for the lipid membranes composed. C24-Ceramide (d18:1/24:0) induces time-dependent changes in membrane properties. C24-Ceramide (d18:1/24:0) induces membrane reorganization [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 102917-80-6. Pack Sizes: 1 mg. Product ID: HY-134508A. | |
| C24-Ceramide-d7 | C24-Ceramide-d 7 is the deuterium labeled C24-Ceramide[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1840942-15-5. Pack Sizes: 1 mg; 5 mg; 500 μg. Product ID: HY-134508S. | |
| C24 Ceramide (Lignoceric Ceramide) | Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of phospholipase C, appropriately named sphingomyelinase. Group: Biochemicals. Alternative Names: Lignoceric Ceramide. Grades: Highly Purified. CAS No. 34435-05-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| C26-Ceramide | C26-Ceramide. Group: Biochemicals. Alternative Names: N- [ (1S, 2R, 3E) -2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] hexacosanamide; [R- [R*, S*- (E) ] ] -N- [2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] hexacosanamide. Grades: Highly Purified. CAS No. 121459-09-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C44H87NO3. US Biological Life Sciences. | Worldwide |
| C26-Dihydro ceramide | C26-Dihydro ceramide. Group: Biochemicals. Alternative Names: N- [ (1S, 2R) -2-Hydroxy-1- (hydroxymethyl) heptadecyl] hexacosanamide; [R- (R*, S*) ] -N- [2-Hydroxy-1- (hydroxymethyl) heptadecyl] hexacosanamide; C26-Dihydroceramide. Grades: Highly Purified. CAS No. 182362-38-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C44H89NO3. US Biological Life Sciences. | Worldwide |
| C2 Adamantanyl Galactosylceramide (d18:1/2:0) | C2 Adamantanyl Galactosylceramide (d18:1/2:0) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively. Synonyms: [(2S,3R,4E)-2-[(1-Adamantyl)acetylamino]-3-hydroxy-4-octadecenyl]beta-D-galactopyranoside; N-(1-Adamantaneacetyl)-galactosylceramide; Adamantanyl Galactosyl(β) Ceramide; AdaGalCer(d18:1/2:0). Grades: ≥98%. CAS No. 574738-16-2. Molecular formula: C36H63NO8. Mole weight: 637.89. | |
| C2-Ceramide | C2-Ceramide. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; N-Acetyl-D-sphingosine; Acetyl ceramide. Grades: Highly Purified. CAS No. 3102-57-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H39NO3. US Biological Life Sciences. | Worldwide |
| C2 Dihydroceramide (N-Acetylsphinganine) | May be used as a negative control for C2 Ceramide. Group: Biochemicals. Alternative Names: N-Acetylsphinganine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1,2,3,4,6-Pentakis-O-(trimethylsilyl) α-D-Galactose | 1,2,3,4,6-Pentakis-O-(trimethylsilyl) α-D-Galactose is useful in the synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide. Synonyms: 1,2,3,4,6-Pentakis-O-(trimethylsilyl)-α-D-galactopyranose. Grades: 97%. CAS No. 32166-80-6. Molecular formula: C21H52O6Si5. Mole weight: 541.06. | |
| 3,4,6-Tri-O-benzyl-D-galactose | 3,4,6-Tri-O-benzyl-D-galactose can be used as a reagent for the stereoselective total synthesis of ceramide. Synonyms: 3,4,6-Tris-O-(phenylmethyl)-α-D-galactopyranose. CAS No. 114179-79-2. Molecular formula: C27H30O6. Mole weight: 450.52. | |
| ARN14974 | ARN14974 is a benzoxazolone carboxamide inhibitor of acid ceramidase with IC50 of 79 nM. It inhibits acid ceramidase activity, reduces levels of sphingosine and dihydroceramide, and increases levels of ceramide in SW403 adenocarcinoma cells and RAW 264.7 murine macrophages when used at concentrations ranging from 0.1 to 20 mM. Synonyms: Acid Ceramidase Inhibitor 17a; ARN-14974; ARN 14974; Acid Ceramidase Inhibitor 17a. Grades: ≥95%. CAS No. 1644158-57-5. Molecular formula: C24H21FN2O3. Mole weight: 404.4. | |
| b-D-Galactopyranoside,(2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl | b-D-Galactopyranoside,(2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: O-Galactosylsphingosine; Psychosine from bovine brain; Galactosylsphingosine; D-GALACTOSYL-B1-1 SPHINGOSN; LYSO-CEREBROSIDE; PSYCHOSIN; PSYCHOSINE; LYSO-CERAMIDEGALACTOSIDE; D-galactosyl-ß1-1-D-erythro-sphingosine; 1-B-D-GALACTOSYLSPHINOGOSINE. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 2238-90-6. Molecular formula: C24H47NO7. Mole weight: 461.63. Purity: 0.96. IUPACName: (2R,3R,4S,5R,6R)-2-[(E)-2-amino-3-hydroxyoctadec-4-enoxy]-6-(hydroxymethyl)oxane-3,4,5-triol. Density: 1.14 g/cm³. Product ID: ACM2238906. Alfa Chemistry ISO 9001:2015 Certified. | |
| b-D-Glucosyl C4-ceramide | b-D-Glucosyl C4-ceramide, a pivotal element extensively employed in the biomedical sector owing to its commendable therapeutic capacities, exhibits an imperative presence in combating numerous ailments, such as cancer and neurodegenerative disorders. Primarily acting as a regulator within cellular signaling cascades, it concomitantly stimulates cellular proliferation and differentiation whilst impeding aberrant processes. Synonyms: [R-[R*,S*-(E)]]-N-[1-[(b-D-Glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecenyl]butanamide. CAS No. 111956-45-7. Molecular formula: C28H53NO8. Mole weight: 531.72. | |
| C3 Ceramide-d5 | C3 Ceramide-d5. Group: Biochemicals. Alternative Names: N- [ (1S, 2R, 3E) -2-hydroxy-1- (hydroxymethyl) -3-heptadecenyl] propanamide-d5; N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]propanamide-d5. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C21H36D5NO3, Molecular Weight: 360.59. US Biological Life Sciences. | Worldwide |
| C4-Ceramide | C4-Ceramide. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]butanamide; N-Butyl-D-sphingosine; Butyl ceramide. Grades: Highly Purified. CAS No. 74713-58-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C22H43NO3. US Biological Life Sciences. | Worldwide |
| C6-Ceramide | C6-Ceramide. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexanamide; N-Hexanoy-D-sphingosine; N-Hexanoylsphingosine. Grades: Highly Purified. CAS No. 124753-97-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H47NO3. US Biological Life Sciences. | Worldwide |
| C8-Ceramide | C8-Ceramide. Group: Biochemicals. Alternative Names: N-Octanoylsphingosine; N- [ (1S, 2R, 3E) -2-hydroxy-1- (hydroxymethyl) -3-heptadecenyl] octanamide; [R- [R*, S*- (E) ] ] -N- [2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] octanamide. Grades: Highly Purified. CAS No. 74713-59-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H51NO3. US Biological Life Sciences. | Worldwide |
| C8 ceramide-1-phosphate | C8 ceramide-1-phosphate. Group: Biochemicals. Alternative Names: N-[2-Hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]octanamide; N-Octanoylsphingosine-1-phosphate. Grades: Highly Purified. CAS No. 887353-95-9. Pack Sizes: 1mg. Molecular Formula: C26H52NO6P. US Biological Life Sciences. | Worldwide |
| Ceramides | Ceramide Powder is the latest moisturizer developed recently. It is a type of phospholipid with ceramide as a skeleton. Ceramide phosphocholine and ceramide phosphoethanolamine are the main components. Phospholipid is the main component of the cell membrane, and the stratum corneum 40%~50% sebum is composed of Ceramide Powder. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide. Appearance: Crystalline solid. CAS No. 100403-19-8. Molecular formula: C24H47NO3. Mole weight: 397.63. Purity: 0.98. Density: 0.928 g/cm³. ECNumber: 309-560-3. Product ID: ACM100403198. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ceranib 1 | Ceranib 1 is a ceramidase inhibitor. It inhibits proliferation in SKOV3 ovarian carcinoma cells. It decreases sphingosine and sphingosine-1-phosphate (S1P) levels in SKOV3 cells and induces accumulation of ceramide species. It is a useful research chemical and has an antiproliferative effect. Synonyms: 3-[(2E)-3-(4-Methoxyphenyl)-1-oxo-2-propen-1-yl]-6-methyl-4-phenyl-2(1H)-quinolinone; 6-Methyl-3-[3-(4-methoxyphenyl)-1-oxo-2-propenyl]-4-phenyl-2(1H)-quinolinone. Grades: ≥98% by HPLC. CAS No. 328076-61-5. Molecular formula: C26H21NO3. Mole weight: 395.45. | |
| Ceranib-2 | Ceranib-2 is an inhibitor of cellular ceramidase activity, which can inhibit ceramidase activity with IC50 of 28 μM in SKOV3 cells. It can catalyze the hydrolysis of the N-acyl linkage between the fatty acid and sphingosine base in ceramide to produce sphingosine and a free fatty acid. Ceranib-2 decreases levels of sphingosine and sphingosine-1-phosphate (S1P), and inhibits cell proliferation. Grades: ≥98%. CAS No. 1402830-75-4. Molecular formula: C25H19NO3. Mole weight: 381.4. | |
| Cerebroside sulfate | Cerebroside sulfate is a remarkable biomedical compound, exhibiting prodigious potential for studying diverse neurological disorders such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. Its distinctive configuration and inherent characteristics render it an alluring contender for novel drug development aiming at the central nervous system. Encouraging outcomes from preclinical investigations substantiate its capacity to transform the research landscape of these incapacitating illnesses. Synonyms: Sulfatides; Ceramide-galactoside-3-sulfate; 3-O-sulfo-b-D-C24-galactosylceramide. CAS No. 85496-63-5. Molecular formula: C42H80NNaO11S. Mole weight: 830.14. | |
| D-erythro-Dihydro-D-sphingosine-1-phosphate | May be used as a negative control for C2 Ceramide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| D-erythro-MAPP | D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase. It increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner. Synonyms: (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol; D-e-MAPP; MAPP, D-erythro. Grades: ≥98%. CAS No. 143492-38-0. Molecular formula: C23H39NO2. Mole weight: 361.6. | |
| DHA Ceramide | DHA Ceramide (C22:6 Ceramide) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C22:6 Ceramide. CAS No. 218608-43-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-165781. | |
| DL-threo-PDMP hydrochloride | DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP: D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 μM. It reduces the synthesis of glucosylceramide, increases cellular ceramide, and induces cell cycle arrest in vitro. Synonyms: DL-PDMP; D,l-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol HCl; SMR000326846. Grades: ≥98%. CAS No. 80938-69-8. Molecular formula: C23H38N2O3·HCl. Mole weight: 427. | |
| DL-threo-PPMP hydrochloride | DL-threo-PPMP is a ceramide analog that inhibits glucosylceramide synthase. It has been used to study the role of glucosylceramide synthase in cell growth, apoptosis, and autophagy. Synonyms: DL-threo-1-Phenyl-2-palmitoylamino-3-morpholino-1-propanol; DL-PPMP; BML3-D12; CTK8E7792. Grades: ≥98%. CAS No. 139974-41-7. Molecular formula: C29H50N2O3·HCl. Mole weight: 511.2. | |
| D-NMAPPD | D-NMAPPD is an inhibitor of ceramidase. It induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner but doesn't have effect on viability of rat hepatocytes, Kupffer cells, or sinusoidal endothelial cells when used at a concentration of 100 mM. It also increases intracellular ceramide accumulation and cytochrome C release and induces apoptosis in SW403 cells. Synonyms: (1R,2R)-B13; CAY10466; N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-tetradecanamide. Grades: ≥98%. CAS No. 35922-06-6. Molecular formula: C23H38N2O5. Mole weight: 422.6. | |
| (+)-D-threo-PDMP hydrochloride | (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. (+)-D-threo-PDMP is an inhibitor of glucosylceramide synthase. Synonyms: d-threo-PDMP; 109836-82-0; 80938-69-8; (+)-D-threo-PDMP (hydrochloride); DL-threo-PDMP (hydrochloride); 139889-62-6; N-[(1R,2R)-1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]decanamide; hydrochloride; N-[(1R,2R)-2-Hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride; SMR000326846; DL-threo-PDMP; (+/-)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride; D-Threo-pdmp-HCl; MLS000859987; MLS002153295; BML3-D11; CHEMBL1255585; EX-A8002H; DTXSID401017468; D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL; AKOS040755898; J-002336; D-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol*HCl; N-((1R,2R)-1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide hydrochloride; Decanamide,N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-,hydrochloride(1:1),rel-. Grades: ≥98%. CAS No. 139889-62-6. Molecular formula: C23H38N2O3·HCl. Mole weight: 427.03. | |
| Hydrolyzed Fumonisin B1 | Hydrolyzed Fumonisin B1 is the backbone and main hydrolysis product of the mycotoxin Fumonisin B1. Hydrolyzed Fumonisin B1 can weakly inhibit ceramide synthase. Synonyms: AP1 Metabolite; Aminopentol; Aminopentol formate salt; 2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol. Grades: ≥95%. CAS No. 145040-09-1. Molecular formula: C22H47NO5. Mole weight: 405.61. | |
| MP-A08 | MP-A08 is a cell permeable selective inhibitor of sphingosine kinase 2 (Ki=6.9 μM) and 1 (Ki=27 μM) with little affinity for other kinases. In vitro: inhibits cellular S1P production and increases sphingosine and ceramide levels. Synonyms: MP-A08; MP A08; MPA08; NSC-122314; NSC 122314; NSC122314; 4- methyl -N- [2- [ [2- [ (4-methyl phenyl ) sulfonyl amino] ph enyl ] imino methyl ] phenyl ] Ben zene sulfonamide MP-A08NSC122314AC1L9JETAmbcb5562335SCHE MBL17443540MCULE-6662772127N- [2- [ [2-(Tosyl amino) benzyl ide ne ] amino ] phenyl ]-4- methyl Benzene sulfonamide MP A08|NSC 1223. CAS No. 219832-49-2. Molecular formula: C27H25N3O4S2. Mole weight: 519.64. | |
| NVP-231 | NVP-231 is a potent, specific, and reversible CerK inhibitor that competitively inhibits binding of ceramide to CerK. NVP-231 is active in the low nanomolar range on purified as well as cellular CerK and abrogates phosphorylation of ceramide, resulting in decreased endogenous C1P levels. When combined with another ceramide metabolizing inhibitor, such as tamoxifen, NVP-231 synergistically increased ceramide levels and reduced cell growth. Therefore, NVP-231 represents a novel and promising compound for controlling ceramide metabolism that may provide insight into CerK physiological function. Synonyms: NVP-231; NVP 231; NVP231. CAS No. 362003-83-6. Molecular formula: C25H25N3O2S. Mole weight: 431.554. | |
| Oleoyl serinol | Oleoyl serinol is an analog of ceramide that acts as an agonist of the cannabinoid receptor GPR119. It has been found to stimulate migration of neural progenitors (NPs) in scratch (wounding) migration assays. It eliminates mouse and human Oct-4(+)/PAR-4(+) cells, preventing teratoma formation, and enriching the embryoid body-derived cells (EBCs) for cells that undergo neural differentiation after transplantation. Synonyms: N-Oleoyl serinol; S-18; (Z)-N-(1,3-dihydroxypropan-2-yl)octadec-9-enamide. Grades: ≥98%. CAS No. 72809-08-6. Molecular formula: C21H41NO3. Mole weight: 355.6. | |
| PDMP hydrochloride | PDMP is an inhibitor of glucosyl ceramide synthase that inhibits the synthesis and shedding of gangliosides. It reduces lysosomal activity, enhances lysosomal permeability and cytotoxicity in cells. PDMP has been used as a tool for studying various effects of endogenous glycosphingolipids. Synonyms: DL-threo-PDMP hydrochloride; DL-erythro/threo-PDMP hydrochloride; 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl; (+/-)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride. Grades: ≥98%. CAS No. 73257-80-4. Molecular formula: C23H38N2O3·HCl. Mole weight: 427. | |
| SPT Imidazopyridine 1 | SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM) used for the treatment of type 2 diabetes and dyslipidemia. SPT Imidazopyridine 1 inhibits incorporation of 14C-serine into ceramide in dose manner, and lowers plasma ceramide levels in vivo. It also has the effect of increasing plasma HDL and reducing VLDL cholesterol levels in rats. Synonyms: SPT-IN-1; SPT IN 1; SPT Inhibitor 1; Imidazopyridine 1; 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid; 2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid; SPT-IN-1. Grades: ≥98%. CAS No. 1933533-18-6. Molecular formula: C22H24N2O3. Mole weight: 364.44. | |
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