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5mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C27H44O3. CAS No. 32222-06-3. Prepack ID 76159527-5mg. Molecular Weight 416.64. See USA prepack pricing.
Calcitriol is the hormonally active form of vitamin D. Synonyms: RO215535, Topitriol. Grades: >98%. CAS No. 32222-06-3. Molecular formula: C27H44O3. Mole weight: 416.64.
Calcitriol
Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor ( VDR ) agonist. Uses: Scientific research. Group: Natural products. Alternative Names: 1,25-Dihydroxyvitamin D3. CAS No. 32222-06-3. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10002.
Calcitriol-d6
The biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Alternative Names: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aS)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol-d6; (1α,3 β,5Z,7E)- 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol-d6; 1 α , 25-Di hydroxycholecalciferol-d6; 1α,25-Dihydroxyvitamin D3-d6; Calcijex-d6; Dihydroxyvitamin D3-d6; Panbonis-d6; Ro 21-5535-d6; Rocaltrol-d6; Silkis-d6; Solbone P-d6; Soltriol-d6; Topitriol-d6; Toptriol. Grades: Highly Purified. CAS No. 78782-99-7. Pack Sizes: 500ug. US Biological Life Sciences.
Calcitriol-dehydroxytri methyl silyl-3, 5-O-tert-butyldi methyl silyl-d6 is an intermediate used in the synthesis of Calcitriol-d6 (C144502), which is the biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C42H74D6O3Si3, Molecular Weight: 723.38. US Biological Life Sciences.
Worldwide
Calcitriol EP Impurity D
Calcitriol EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 103656-40-2. Molecular formula: C28H46O3. Mole weight: 430.66. Catalog: APB103656402.
Calcitriol Impurity 1
Calcitriol Impurity 1 is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Molecular formula: C27H44O3. Mole weight: 416.645.
Calcitriol Impurity 2
Calcitriol Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 169900-32-7. Molecular formula: C39H70O4Si2. Mole weight: 659.15. Catalog: APB169900327.
Calcitriol Impurity 6
Calcitriol Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 100928-05-0. Molecular formula: C19H37IOSi. Mole weight: 436.49. Catalog: APB100928050.
Calcitriol Impurity 9
Calcitriol Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104651-47-0. Molecular formula: C19H36O2Si. Mole weight: 324.58. Catalog: APB104651470.
Calcitriol Intermediate
A derivative of vitamin D3 and an intermediate of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Synonyms: (5R)-ethyl-5-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-2-methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)hexanoate. CAS No. 169900-32-7. Molecular formula: C39H72O4Si2. Mole weight: 661.171.
Calcitriol Lactone
Calcitriol Lactone is a metabolite of Calcitriol (C144500), which is an active form of Vitamin D3. Calcitriol is also a calcium regulator. Group: Biochemicals. Grades: Highly Purified. CAS No. 81203-50-1. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H40O5, Molecular Weight: 444.6. US Biological Life Sciences.
Worldwide
Calcitriol (Vitamin D3)
The biologically active form of Vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Alternative Names: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aS)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; (1α,3 β,5Z,7E)- 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,; 1 α , 25-Di hydroxycholecalcife rol; 1α,25-Dihydroxyvitamin D3; Calcijex; Dihydroxyvitamin D3; Panbonis; Ro 21-5535; Rocaltrol; Silkis; Solbone P; Soltriol; Topitriol; Toptriol. Grades: Highly Purified. CAS No. 32222-06-3. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??O?, Molecular Weight: 416.64. US Biological Life Sciences.
1,3-bi-TBS-trans-Calcitriol is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Synonyms: (6R)-6-[(1R,3aS,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethyl]-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]-2-methylheptan-2-ol. CAS No. 140710-98-1. Molecular formula: C39H74O3Si2. Mole weight: 647.188.
1-b-Calcitriol
1-b-Calcitriol. Group: Biochemicals. Grades: Highly Purified. CAS No. 66791-17-7. Pack Sizes: 10mg, 25mg. US Biological Life Sciences.
Worldwide
1-epi-Calcitriol
1-epi-Calcitriol. Group: Biochemicals. Alternative Names: (1b,3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; 1-Epicalcitriol; 1b, 25-Di hydroxycholecalcife rol. Grades: Highly Purified. CAS No. 66791-71-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C27H44O3. US Biological Life Sciences.
Worldwide
1-epi-Calcitriol
1-epi-Calcitriol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 66791-71-7. Pack Sizes: 10MG. Molecular formula: C27H44O3. Mole weight: 416.64. Catalog: APS66791717. Format: Neat. Shipping: Dry ice.
(1S)-Calcitriol
(1S)-Calcitriol is an isomer of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Synonyms: (1S)-Calcitriol; 61476-45-7; 1-alpha,25-Dihydroxy-3-epi Vitamin D3; (1s,3s,5z,7e,14beta,17alpha)-9,10-Secocholesta-5,7,10-Triene-1,3,25-Triol; (5Z,7E)-(1S,3S)-9,10-seco-5,7,10(19)-cholestatriene-1,3,25-triol; 1alpha,25-dihydroxy-3-epivitamin D3 / 1alpha,25-dihydroxy-3-epicholecalciferol; SCHEMBL17299281; DTXSID60860465; HY-10002A; LMST03020259; MFCD28963706; 1?,25-Dihydroxy-3-epi-vitamin-D3; 1alpha,25-Dihydroxy-3-epivitamin D3; AKOS040754678; 1alpha,25-dihydroxy-3-epi-vitamin D3; (1S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol; MS-27266; CS-0166654; F82871; Q27453764; 3EV. Molecular formula: C27H44O3. Mole weight: 416.645.
24-Homo calcitriol
24-Homo calcitriol. Group: Biochemicals. Alternative Names: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-6-hydroxy-1,6-dimethylheptyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; 24-Homo-1,25-dihydroxyvitamin D3; MC 1127. Grades: Highly Purified. CAS No. 103656-40-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C28H46O3. US Biological Life Sciences.
Worldwide
24-Homo Calcitriol
One of the impurities of Calcitriol, an active metabolite of VD3, could be a agonist of vitamin D receptor. Uses: One of the impurities of calcitriol and could be a agonist of vitamin d receptor. Synonyms: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-6-hydroxy-1,6-dimethylheptyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; 24-Homo-1,25-dihydroxyvitamin D3; MC 1127. Grades: 95%. CAS No. 103656-40-2. Molecular formula: C28H46O3. Mole weight: 430.66.
5,6-trans Calcitriol
5,6-trans Calcitriol is an impurity of Calcitriol, which is the hormonally active form of vitamin D and is the active metabolite of vitamin D3. It is the trans isomer of Calcitriol. It is used as a control product to study calcitriol. Uses: Bone density conservation agents. Synonyms: Calcitriol Impurities A; (5E,7E)-(1S,3R)-9,10-seco-5,7,10(19)-cholestatriene-1,3,25-triol; (1α,3β,5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; 1α,25-Dihydroxy-5,6-trans-vitamin D3; (1R,3S,E)-5-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol; trans-Calcitriol. Grades: 98%. CAS No. 73837-24-8. Molecular formula: C27H44O3. Mole weight: 416.64.
5,6-trans-Calcitriol
5,6-trans-Calcitriol. Group: Biochemicals. Alternative Names: (1R,3S,5E)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aS)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; (1a,3b,5E,7E)- 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; 1,25-Dihydroxy-5,6-trans-vitamin D3. Grades: Highly Purified. CAS No. 73837-24-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H44O3. US Biological Life Sciences.
Worldwide
5,6-trans-Calcitriol-d6
An impurity of Calcitriol. The trans isomer of Calcitriol. Group: Biochemicals. Alternative Names: (1R,3S,5E)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aS)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol-d6; (1α,3 β,5E,7E)- 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol-d6; 1,25-Dihydroxy-5,6-trans-vitamin D3-d6; 1α,25-Dihydroxy-5,6-trans-vitamin D3-d6; 5,6-trans-1α,25-Dihydroxyvitamin D3-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Impurity B of Calcitriol is the hormonally active form of vitamin D, and Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR), which inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. Synonyms: 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol. Grades: >98%. CAS No. 66791-71-7. Molecular formula: C27H44O3. Mole weight: 416.64.
Ercalcitriol
Ercalcitriol is an active metabolite of vitamin D2. It exhibits equipotent antirachitic activity in rats as calcitriol. Synonyms: RO-17-6218; RO 17-6218; RO17-6218; 1α,25-Dihydroxy Vitamin D2; 1,25-Dihydroxycalciferol; 1alpha,25-Dihydroxyvitamin D2; 1,25-Dihydroxyergocalciferol. Grades: >98%. CAS No. 60133-18-8. Molecular formula: C28H44O3. Mole weight: 428.65.
Falecalcitriol
Falecalcitriol(Fulstan; Hornel) is an analog of calcitriol; has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo. Uses: Scientific research. Group: Signaling pathways. CAS No. 83805-11-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-32342.
Falecalcitriol
Falecalcitriol is an analog of calcitriol. It has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo. Uses: Dermatologic agents. Synonyms: Ro 23-4194; Ro-23-4194; Ro23-4194; ST 630; ST-630; ST630; Flocalcitriol; Hornel, Fulstan; Falecalcitriol. Grades: >98%. CAS No. 83805-11-2. Molecular formula: C27H38F6O3. Mole weight: 524.58.
methylene calcitriol
Methylene calcitriol is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Synonyms: (5Z,7E)-1α,3β-dihydroxy-17-((R)-7-hydroxy-7-methyl-octan-2-yl)-9,10-secoandrosta-5,7,10(19)-triene. CAS No. 1428946-52-4. Molecular formula: C28H44O3. Mole weight: 428.65.
Impurity C of Calcitriol is the impurity C of Calcitriol, which is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Synonyms: 1H,5H-Cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione, 11-(3,5-dihydroxy-2-methyl-1-cyclohexen-1-yl)-4a,6,6a,7,8,9,9a,11-octahydro-7-(5-hydroxy-1,5-dimethylhexyl)-6a-methyl-2-phenyl-, [4aR-[4aα, 6aα, 7α(R*), 9aβ, 11α(3S*, 5R*)]]- (9CI). Grades: >98%. CAS No. 86307-44-0. Molecular formula: C35H49N3O5. Mole weight: 591.78.
1,6-Epoxyisodihydrocarvone is an intermediate in synthesizing Calcitriol-d6 (C144502), the biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. (εR, 1R, 3aR, 4S, 7aR)-Octahydro-4-hydroxy-α, α, ε, 7a-tetramethyl-1H-indene-1-pentanol-d6 is also a labelled analogue of (εR, 1R, 3aR, 4S, 7aR)-Octahydro-4-hydroxy-α, α, ε, 7a-tetramethyl-1H-indene-1-pentanol (O236455). Group: Biochemicals. Grades: Highly Purified. CAS No. 39903-97-4. Pack Sizes: 10g, 25g. Molecular Formula: C10H14O2. US Biological Life Sciences.
1-alpha-25-Dihydroxycholecalciferol Impurity 1 is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Molecular formula: C27H44O3. Mole weight: 416.645.
1-alpha-25-Dihydroxycholecalciferol Impurity 2
1-alpha-25-Dihydroxycholecalciferol Impurity 2 is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Molecular formula: C27H44O3. Mole weight: 416.645.
(1α,3 β,10α)-Cholesta-5,7-diene-1,3,25-triol
(1α,3 β,10α)-Cholesta-5,7-diene-1,3,25-triol is a natural secondary steroid used to determine the signal transduction pathways for rapid and genomic responses to calcitriol discrimination between different agonist shapes. Group: Biochemicals. Grades: Highly Purified. CAS No. 156197-52-3. Pack Sizes: 500ug, 5mg. Molecular Formula: C27H44O3. US Biological Life Sciences.
(1α,3 β)-9,10-Secocholesta-5(10),8-dien-6-yne-1,3,25-triol is an intermediate in synthesizing (1α,3 β,9 β)-Cholesta-5,7-diene-1,3,25-triol (C431410), which is a natural secondary steroid used to determine the signal transduction pathways for rapid and genomic responses to calcitriol discrimination between different agonist shapes. Group: Biochemicals. Grades: Highly Purified. CAS No. 134458-49-4. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H42O3. US Biological Life Sciences.
Worldwide
(1α,3 β,9 β)-Cholesta-5,7-diene-1,3,25-triol
(1α,3 β,9 β)-Cholesta-5,7-diene-1,3,25-triol is a natural secondary steroid used to determine the signal transduction pathways for rapid and genomic responses to calcitriol discrimination between different agonist shapes. Group: Biochemicals. Grades: Highly Purified. CAS No. 168609-17-4. Pack Sizes: 500ug, 5mg. Molecular Formula: C27H44O3. US Biological Life Sciences.
(1R, 3aR, 7aR) -1-[ (1R) -1, 5-Dimethyl-5-[ (trimethylsilyl) oxy]hexyl]-2, 3, 3a, 6, 7, 7a-hexahydro-7a-methyl-1H-inden-4-yl Ester 1,1,1-Trifluoro-methanesulfonic Acid is an intermediate in synthesizing (1α,3 β,9 β)-Cholesta-5,7-diene-1,3,25-triol (C431410), which is a natural secondary steroid used to determine the signal transduction pathways for rapid and genomic responses to calcitriol discrimination between different agonist shapes. Group: Biochemicals. Grades: Highly Purified. CAS No. 222317-53-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H39F3O4SSi. US Biological Life Sciences.
(1R, 3aR, 7aR) -1-[ (1R) -1, 5-Dimethyl-5-[ (trimethylsilyl) oxy]hexyl]octahydro-7a-methyl-4H-inden-4-one is an intermediate in synthesizing (1α,3 β,9 β)-Cholesta-5,7-diene-1,3,25-triol (C431410), which is a natural secondary steroid used to determine the signal transduction pathways for rapid and genomic responses to calcitriol discrimination between different agonist shapes. Group: Biochemicals. Grades: Highly Purified. CAS No. 81506-41-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H40O2Si. US Biological Life Sciences.
(1R, 3aR, 7aR) -1-[ (1R) -1, 5-Dimethyl-5-[ (trimethylsilyl) oxy]hexyl]octahydro-7a-methyl-4H-inden-4-one-d6 is an intermediate used in the synthesis of Calcitriol-d6 (C144502), which is the biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 122958-40-1. Pack Sizes: 500ug, 1mg. Molecular Formula: C21H34D6O2Si, Molecular Weight: 358.66. US Biological Life Sciences.
(1R,7AR)-1-((R)-6-Hydroxy-6-methylheptan-2-yl)-7A-methylhexahydro-1H-inden-4(2H)-one-d6 is an intermediate used in the synthesis of Calcitriol-d6 (C144502), which is the biologically active form of vitamin D3. Calcitriol-d6 is a calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C18H26D6O2, Molecular Weight: 286.48. US Biological Life Sciences.
(1S, 2R, 4S, 6S)-2-Ethynyl-1-methyl-7-oxabicyclo[4. 1. 0]heptane-2, 4-diyl Diacetate is an intermediate in synthesizing (1α,3 β,9 β)-Cholesta-5,7-diene-1,3,25-triol (C431410), which is a natural secondary steroid used to determine the signal transduction pathways for rapid and genomic responses to calcitriol discrimination between different agonist shapes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H16O5. US Biological Life Sciences.
(1S, 4S, 6S) -4-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-1-methyl-7-oxabicyclo[4. 1. 0]heptan-2-one is an intermediate used in the synthesis of Calcitriol-d6 (C144502), which is the biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 326496-92-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C13H24O3Si, Molecular Weight: 256.41. US Biological Life Sciences.
Worldwide
(24S)-MC 976
(24S)-MC 976 is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: rac-(5Z,7E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19)-triene-1α,3β,24-triol; Calcipotriol EP Impurity E. Grades: >98%. CAS No. 112849-14-6. Molecular formula: C27H42O3. Mole weight: 414.63.
25-Hydroxy Vitamin D3 3,3-Aminopropyl Ether
Vitamin D3 analog. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5- (3-Aminopropoxy) -2- methyl enecyclohexylidene] ethylidene] octahydro- α , α , ε , 7a-tetra methyl -1H-indene-1-pentanol; (3 β,5Z,7E)-3-(3-Aminopropoxy)-9,10-secocholesta-5,7,10(19)-trien-25-ol; 3-O-(2-Aminoethyl)-25-hydroxyvitamin D3. Grades: Highly Purified. CAS No. 163018-26-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
25-Hydroxy Vitamin D3 3-Sulfate Sodium Salt
25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days. Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol 3-(Hydrogen Sulfate) Sodium Salt; 25-Hydroxyvitamin D3 3-Sulfate Sodium Salt; 25-Hydroxyvitamin D3 3 β-Sulfate Sodium Salt; Calcifediol 3-Sulfate Sodium Salt. Grades: Purified. Pack Sizes: 2.5mg. Molecular Formula: C??H??NaO?S, Molecular Weight: 502.68. US Biological Life Sciences.
(2Z) -[ (1R, 4R, 6S) -4-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-1-methyl-7-oxabicyclo[4. 1. 0]hept-2-ylidene]-acetic Acid Ethyl Ester is an intermediate used in the synthesis of Calcitriol-d6 (C144502), which is the biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 326496-94-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C17H30O4Si, Molecular Weight: 326.5. US Biological Life Sciences.
(2Z) -2- [ (3S, 5R) -3, 5-Bis [ [ (1, 1-di methyl ethyl) di methyl silyl] oxy] -2- methyl enecyclohexylidene] ethanol is a useful synthetic intermediate in the synthesis of 24-Homo Calcitriol (H589800); a Calcitriol (C144500) analog with potent effects on cell growth regulation and immune responses. Group: Biochemicals. Grades: Highly Purified. CAS No. 81506-24-3. Pack Sizes: 25mg, 50mg. Molecular Formula: C21H42O3Si2. US Biological Life Sciences.
Worldwide
3-epi-25-Hydroxy Vitamin D3
The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -Octahydro-4- [ (2Z) -2- [ (5R) -5-hydroxy-2- methyl enecyclohexylidene] ethylidene] - α , α , ε , 7a-tetra methyl -H-indene-1-pentanol; (3α,5Z,7E)-9,10-Seco-cholesta-5,7,10(19)-triene-3,25-diol; 3-epi-25-Hydroxyvitamin D3. Grades: Highly Purified. CAS No. 73809-05-9. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Calcifediol
Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 25-hydroxy Vitamin D3. CAS No. 19356-17-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32351.
Calcifediol monohydrate
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 25-hydroxy Vitamin D3 monohydrate. CAS No. 63283-36-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32351A.
Calcipotriene β-Isomer
Calcipotriene β-Isomer is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Molecular formula: C27H40O3. Mole weight: 412.62.
Calcipotriol (Calcipotriene) Monohydrate
Calcipotriol increased hCAP18 mRNA expression in IL-17/IL-22-stimulated keratinocytes. However, LL37 peptide in the culture supernatants was reduced by calcipotriol. Calcipotriol and FTY720 augment IL-2-activated NK cell lysis of K562 and RAJI tumor cell lines as well as immature (I) and mature (m) DCs, with variable efficacies.vitamin D3, calcipotriol and FTY720 enhance NK17/NK1 cell lysis of K562 cells, suggesting that a possible mechanism of action for these drugs is via activating these newly described cells. MC 903 (calcipotriol) is a novel vitamin D3 analogue which is at least 100 times less potent than 1,25-(OH)-2-D3 in its effects on calcium homeostasis. A total of 160 SKH-1 mice were randomized to one placebo group and four chemoprevention groups (diclofenac plus difluoromethylornithine; diclofenac plus calcipotriol; difluoromethylornithine plus calcitriol; and diclofenac plus difluoromethylornithine plus calcipotriol). Synonyms: Calcipotriol monohydrate. Grades: >98%. CAS No. 147657-22-5. Molecular formula: C27H42O4. Mole weight: 430.62.
Calcipotriol Impurity 2
Calcipotriol Impurity 2 is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Molecular formula: C27H40O3. Mole weight: 412.62.
Calcitroic Acid
Calcitroic Acid is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Synonyms: 1alpha-Hydroxy-23-carboxytetranorvitamin D; (3R) -3- [ (1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (3S, 5R) -3, 5-dihydroxy-2-methylidenecyclohexylidene] ethylidene] -7a-methyl-2, 3, 3a, 5, 6, 7-hexahydro-1H-inden-1-yl] butanoic acid. CAS No. 71204-89-2. Molecular formula: C23H34O4. Mole weight: 374.521.
Carbomer Copolymer Type A, NF
Carbomer Copolymer Type A, NF. Grades: NF. Product ID: 8-04881. Properties: calcitriol or Vitamin D derivative, used for psoriasis treatment.
Vitamin D3 is cholecalciferol, one of the vitamin D family. Vitamin D3 has been used to prevent and treat breast cancer, prostate and possibly other cancers and Vitamin D3 is essential to maintain bone density. Vitamin D3 is necessary for the ultilization of Calcium and Phosphorus, and for the assimilation of Vitamin A. It also has a strong immune enhancing effect. In many ways vitamin D acts as a hormone and is potent in minute quantities. One microgram of cholecalciferol has 40 IU of vitamin D activity. Vitamin D is necessary for utilization of calcium and phosphorus. Activated 7-dehydrocholesterol, cholecalciferol, also called activated 7-dehydrocholesterol, cholecalciferol. The biologically active form of Vitamin D. It is transported by the blood and the liver converts it to 25-Hydroxycholecalciferol (25-Hydroxyvitamin D, Calcidiol) which is converted in the kidneys to 1, 25-Di hydroxycholecalciferol (1,25-Dihydroxyvitamin D, Calcitriol). Group: Biochemicals. Alternative Names: Vitamin D3; Activated 7-dehydrocholesterol. Grades: Cell Culture Grade. CAS No. 67-97-0. Pack Sizes: 1g, 5x1g. US Biological Life Sciences.
Worldwide
Inecalcitol
Inecalcitol is an anologue of calcitriol. It is a VDR agonist with antineoplastic activity. Synonyms: TX-522; 19-Nor-14-epi-23-yne-1,25 dihydroxyvitamin D3. Grades: 95%. CAS No. 163217-09-2. Molecular formula: C26H40O3. Mole weight: 400.59.
MC 976
Calcipotriol Impurity 3 is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: MC 976; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-5-cyclopropyl-5-hydroxypentan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol. Grades: >98%. CAS No. 129831-99-8. Molecular formula: C27H42O3. Mole weight: 414.63.
MN-201
MN-201 is an orally administered vitamin D5 analog for the treatment of cancer. MN-201 is the first synthetic vitamin D5 receptor ligand (VDRL) to be advanced into clinical trials for a variety of cancers including breast, prostate and colon cancers. In preclinical studies, MN-201 demonstrated broad anti-tumor activity in cancer cells. In animal models, oral administration of MN-201 also resulted in anti-tumor activity including tumor regression in xenograft models of major solid tumor types. In contrast to treatment with other vitamin D(3) analogs and the naturally occurring vitamin D hormone, calcitriol, favorable anticancer effects with MN-201 were observed in the absence of significantly raised calcium levels. Synonyms: MN 201; MN201; 1alpha-hydroxy-24-ethylcholecalciferol. CAS No. 187935-17-7. Molecular formula: C29H48O2. Mole weight: 428.70.
Seocalcitol
Seocalcitol is a synthetic vitamin D analog which is 50-200 times more potent than calcitriol at inhibiting cell proliferation and differentiation. It has been shown to promote tumor regression in vitro by inducing apoptosis. Synonyms: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4E)-6-Ethyl-6-hydroxy-1-methyl-2,4-octadien-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol; [1R-[1α(1R*, 2E, 4E), 3aβ, 4E(1R*, 3S*, 5Z), 7aα]]-5-[[1-(6-Ethyl-6-hydroxy-1-methyl-2, 4-octadienyl)octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1, 3-Cyclohexanediol; (1R,3S,5Z)-5-[(2E)-[(1R,3aS,7aR)-1-[(1R,2E,4E)-6-Ethyl-6-hydroxy-1-methyl-2,4-octadienyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol. Grades: 95% by HPLC. CAS No. 134404-52-7. Molecular formula: C30H46O3. Mole weight: 454.68.
vitamin D3 24-hydroxylase
This mitochondrial cytochrome P-450 enzyme requires adrenodoxin. The enzyme can perform up to 6 rounds of hydroxylation of the substrate calcitriol leading to calcitroic acid. The human enzyme also shows 23-hydroxylating activity leading to 1,25 dihydroxyvitamin D3-26,23-lactone as end product while the mouse and rat enzymes do not. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: CYP24A1. Enzyme Commission Number: EC 1.14.15.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0941; vitamin D3 24-hydroxylase; EC 1.14.15.16; CYP24A1. Cat No: EXWM-0941.
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