Calmodulin Dep Suppliers USA
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Product | Description | |
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2'- (N-Methylanthraniloyl) guanosine 3',5'-Cyclicmonophosphate, Sodium Salt (MANT-cGMP) Quick inquiry Where to buy Suppliers range | A blue fluorescent derivative of cGMP is a useful substrate the assay of cyclic nucleotide phosphdiesterase. Also inhibits calmodulin-dependent activation of cyclic nucleotide phosphodiesterase by peptide segments of HIV envelope glycoproteins has been monitored using MANT-cGMP.Fluorescence: max. Abs. 359nm; max. Em. 448nm; e x 10-3: 5.2. Group: Biochemicals. Alternative Names: Cyclic 3,5-(hydrogen phosphate) 2-[2-(methylamino)benzoate] Guanosine Monosodium Salt; MANT-cGMP. Grades: Highly Purified. CAS No. 221905-46-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Autocamtide-2 Related Inhibitory Peptide Quick inquiry Where to buy Suppliers range | The Autocamtide-2 Related Inhibitory Peptide controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 500μG. Mole weight: 1497.74. Catalog: IAR42415236. Assay: ≥97% (HPLC). | |
Autocamtide-2-Related Inhibitory Peptide Quick inquiry Where to buy Suppliers range | Autocamtide-2-related inhibitory peptide is a highly selective, specific and potent inhibitor of calmodulin-dependent protein kinase II (CaM kinase II) with I50 value of 40 nM. It is selective over PKC, PKA and CaM kinase IV. Synonyms: AIP; [Ala9]-Autocamtide 2. Grades: ≥97% by HPLC. CAS No. 167114-91-2. Molecular formula: C64H116N22O19. Mole weight: 1497.74. | |
Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable Quick inquiry Where to buy Suppliers range | The Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 1MG. Mole weight: 3873.63. Catalog: IAR42415238. Assay: ≥97% (HPLC). | |
Autocamtide-2-related inhibitory peptide, myristoylated Quick inquiry Where to buy Suppliers range | It is a myristoylated form of Autocamtide-2-Related Inhibitory Peptide (AIP), and acts as a highly potent and specific substrate competitive inhibitor of Calmodulin-Dependent Protein Kinase ll (CaMKII). AIP is derived from Autocamtide-2, a substrate for CaMKII, with the Thr-9 phosphorylation site substituted with Ala. Uses: Peptide Inhibitors. CAS No. 201422-04-0. Product ID: R0844. | |
Autocamtide-2 Related Inhibitory Peptide, Myristoylated Quick inquiry Where to buy Suppliers range | The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 500μG. Mole weight: 1708.10. Catalog: IAR42415237. Assay: ≥97% (HPLC). | |
Autocamtide-2-related inhibitory peptide TFA Quick inquiry Where to buy Suppliers range | Autocamtide-2-related inhibitory peptide TFA is a highly selective, specific and potent inhibitor of calmodulin-dependent protein kinase II (CaM kinase II). Synonyms: H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH.TFA; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-leucine trifluoroacetic acid; Autocamtide-2-Related Inhibitory Peptide Trifluoroacetate; CaM kinase II inhibitor TFA salt. Grades: ≥98%. Molecular formula: C64H116N22O19.C2HF3O2. Mole weight: 1611.76. | |
Calmodulin-Dependent Protein Kinase II 281-309 Quick inquiry Where to buy Suppliers range | Calmodulin-Dependent Protein Kinase II (281-309) is a peptide of calcium/calmodulin-dependent protein kinase II (CaM-kinase II). Uses: Peptide Inhibitors. CAS No. 116826-37-0. Product ID: R1267. | |
Calmodulin-Dependent Protein Kinase II 290-309 Quick inquiry Where to buy Suppliers range | Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with IC50 of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. It has been used in the study of CaM binding, autophosphorylatio and dynamics. Synonyms: Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala; L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparagyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-threonyl-L-threonyl-L-methionyl-L-leucyl-L-alanine; CaM kinase II (290-309); Calmodulin-dependent Protein Kinase II fragment 290-309. Grades: ≥97% by HPLC. CAS No. 115044-69-4. Molecular formula: C103H185N31O24S. Mole weight: 2273.83. | |
Calmodulin-Dependent Protein Kinase II 290-309 Quick inquiry Where to buy Suppliers range | Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II. Uses: Peptide Inhibitors. CAS No. 115044-69-4. Product ID: R1268. | |
Calmodulin-Dependent Protein Kinase II (290-309) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC50 value of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. Calmodulin-dependent protein kinase II (290-309) has been used in the study of CaM binding, autophosphorylation, and dynamics. Grades: ≥95%. Molecular formula: C103H185N31O24S·xCF3COOH. Mole weight: 2273.83. | |
Calmodulin-dependent Protein Kinase II fragment 290-309 Quick inquiry Where to buy Suppliers range | ≥97% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 115044-69-4. Pack Sizes: 1MG. Mole weight: 2273.83. Catalog: AP115044694-B. Assay: ≥97% (HPLC). | |
D-erythro-Sphingosine Quick inquiry Where to buy Suppliers range | D-erythro-Sphingosine is a natural isomer of sphingosine and acts as an inhibitor of protein kinase C and calmodulin-dependent enzymes with no effects on protein kinase A or myosin light chain kinase. It may stimulate mast cells by activation of protein kinase C. Synonyms: Sphingosine (d18:1); sphingosine; D-Sphingosine; 4-Sphingenine; 2S, 3R(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol; (2S,3R,4E)-2-amino-1,3-octadec-4-enediolsphing-4-enine. Grades: >99%. CAS No. 123-78-4. Molecular formula: C18H37NO2. Mole weight: 299.49. | |
Fmoc-erythro-Sphingosine ( (2S, 3R, 4E) -2-Fluorenyl methoxycarbonyl amino-4-octadecen-1, 3-diol) Quick inquiry Where to buy Suppliers range | The N-Fmoc protected Sphingosine, a selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes. Group: Biochemicals. Alternative Names: (2S, 3R, 4E) -2-Fluorenyl methoxycarbonyl amino-4-octadecen-1, 3-diol. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
K 259-2 Quick inquiry Where to buy Suppliers range | K-259-2, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase, was isolated from the cultured broth of Micromonospora olivasterospora K-259. IC50 values for the effect of K-259-2 against Ca2+ and calmodulin-stimulated activity of the enzyme preparations from bovine brain and heart were 6.6 and 2.9 microM, respectively. Synonyms: K-259-2; 1,6,8-Trihydroxy-3-[(Z)-2-ethyl-2-butenyl]-9,10-dihydro-9,10-dioxoanthracene-2-carboxylic acid. CAS No. 102819-46-5. Molecular formula: C21H18O7. Mole weight: 382.36. | |
MS-282a Quick inquiry Where to buy Suppliers range | MS-282a is produced by the strain of Streptomyces tauricus. It inhibits calmodulin-dependent MLCK with an IC50 of 3.8 μmol/L. It has anti-gram-positive bacteria activity. Synonyms: MS-282-A. CAS No. 152158-04-8. Molecular formula: C37H65NO7. Mole weight: 635.91. | |
MS-282b Quick inquiry Where to buy Suppliers range | MS-282b is produced by the strain of Streptomyces tauricus. It inhibits calmodulin-dependent MLCK with an IC50 of 5.2 μmol/L. It has anti-gram-positive bacteria activity. Synonyms: MS-282-B. CAS No. 152759-50-7. Molecular formula: C37H65NO7. Mole weight: 635.91. | |
N-Boc-erythro-sphingosine-13C2,D2 Quick inquiry Where to buy Suppliers range | Labelled N-Boc protected Sphingosine, a selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
N-Boc-erythro-sphingosine ((2S,3R,4E)-2-tert-Butyloxycarbonylamino-4-octadecen-1,3-diol) Quick inquiry Where to buy Suppliers range | The N-Boc protected Sphingosine, a selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes. Group: Biochemicals. Alternative Names: (2S,3R,4E)-2-tert-Butyloxycarbonylamino-4-octadecen-1,3-diol. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Sphingosine (D-erythro-Sphingosine) Quick inquiry Where to buy Suppliers range | Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine. Group: Biochemicals. Alternative Names: (2S,3R,4E)-2-Aminooctadec-4-ene-1,3-diol; trans-D-erythro-2-Amino-4-octadecene-1,3-diol; 4-Sphingenine; D-erythro-Sphingosine. Grades: Highly Purified. CAS No. 123-78-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??NO?, Molecular Weight: 299.49. US Biological Life Sciences. | Worldwide |
STO-609 acetate Quick inquiry Where to buy Suppliers range | STO-609 acetate is a selective and cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (CaMKK) (Ki = 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ, respectively). It displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. STO-609 can be used as a tool for evaluating the physiological significance of the CaM-KK-mediated pathway in vivo and in vitro. Synonyms: STO-609 acetate; STO 609 acetate; STO609 acetate; 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate. Grades: ≥98% by HPLC. CAS No. 1173022-21-3. Molecular formula: C19H10N2O3.C2H4O2. Mole weight: 374.35. | |
Syntide 2 Quick inquiry Where to buy Suppliers range | Syntide 2, a synthetic peptide, is recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII) (Ki= 12 μM) and protein kinase C (Km = 11 μM). Synonyms: Calmodulin-Dependent Protein Kinase Substrate; Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys; L-prolyl-L-leucyl-L-alanyl-L-arginyl-L-threonyl-L-leucyl-L-seryl-L-valyl-L-alanyl-glycyl-L-leucyl-L-prolyl-glycyl-L-lysyl-L-lysine; Syntide-2; Syntide2. Grades: ≥97% by HPLC. CAS No. 108334-68-5. Molecular formula: C68H122N20O18. Mole weight: 1507.82. | |
W-5, Hydrochloride - CAS 61714-25-8 Quick inquiry Where to buy Suppliers range | A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 230 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 240 μM). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 61714-25-8. Pack Sizes: 1MG. Mole weight: 306.42 (free base basis). Catalog: AP61714258-B. Assay: ≥98% (NMR). | |
W-7 hydrochloride Quick inquiry Where to buy Suppliers range | W-7 hydrochloride is a calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM) and myosin light chain kinase (IC50 = 51 μM). W-7 is used as a vascular relaxing agent. Uses: Vascular relaxing agent. Synonyms: W-7 hydrochloride; W-7 hydrochloride; W-7 hydrochloride; W-7 HCl; W 7 HCl; W7 HCl; N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 61714-27-0. Molecular formula: C16H21ClN2O2S.HCl. Mole weight: 377.33. | |
W-7, Hydrochloride - CAS 61714-27-0 Quick inquiry Where to buy Suppliers range | A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 51 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 61714-27-0. Pack Sizes: 10MG. Mole weight: 340.87 (free base basis). Catalog: AP61714270-B. Assay: ≥98% (TLC). |