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| Product | Description | |
|---|---|---|
| Carbocyclic 2'-deoxyguanosine | Carbocyclic 2'-deoxyguanosine is a crucial compound in biomedicine used for studying antiviral drug development. It plays a pivotal role in the treatment of DNA viruses like human immunodeficiency virus (HIV) and hepatitis B virus (HBV). Its unique structure helps to understand the mechanism of viral replication and design effective therapeutic strategies. Synonyms: 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]-, [1R-(1alpha,3alpha,4alpha)]-. CAS No. 137490-72-3. Molecular formula: C11H15N5O3. Mole weight: 265.27. |  |
| Carbocyclic 2'-deoxyguanosine 5'-triphosphate | Carbocyclic 2'-deoxyguanosine 5'-triphosphate, a pivotal constituent employed in biomedicine for diverse applications, manifests itself as an indispensable cornerstone in antiviral drug synthesis. Efficaciously tailored to mitigate DNA viral-induced infections, this compound's synthesis facilitates combat against such afflictions as herpesviruses and poxviruses. Prominently distinguished by its singular structure, this product emerges as an instrumental catalyst in propelling the progression of targeted therapeutic interventions. Synonyms: Cdg-TP; 2-Amino-1,9-dihydro-9-(3-hydroxy-4-((phosphonooxy)methyl)cyclopentyl)-, (1R-(1alpha,3beta,4alpha))-6H-purin-6-one. CAS No. 118905-01-4. Molecular formula: C11H16N5O6P. Mole weight: 345.25. | |
| (1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester | (1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 168958-19-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H19NO4. US Biological Life Sciences. |  Worldwide |
| (1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol | (1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol is an intermediate used in the synthesis of ent-Abacavir, which is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. CAS No. 216481-88-8. Molecular formula: C11H12ClN5O. Mole weight: 265.7. | |
| 2'-(R)-Hydroxy-2',3'-dihydroabacavir Dihydrochloride | 2'-(R)-Hydroxy-2',3'dihydroabacavir is the impurity of Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H20N6O2 2HCl, Molecular Weight: 304.357291999999. US Biological Life Sciences. | Worldwide |
| 6H-?Purin-?6-?one, 2-?amino-?9-?[ (1R, ?2S, ?3R, ?4R)?-?2, ?3-?dihydroxy-?4-? (hydroxymethyl)?cyclopentyl]?-?1, ?9-?dihydro- | HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. Synonyms: 6H-Purin-6-one, 2-amino-9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro-, [1R-(1α, 2β, 3β, 4α)]-; 2-Amino-9-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro-6H-purin-6-one; D-Carbocyclic-2'-deoxyguanosine. Grades: ≥98% (HPLC). CAS No. 111687-37-7. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester | Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Molecular formula: C33H46N6O10. Mole weight: 686.75. | |
| Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine | Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir USP Related Compound D; Abacavir EP Impurity B; Abacavir Impurities; Abacavir EP Impurity B. CAS No. 1443421-69-9. Molecular formula: C18H21ClN10O. Mole weight: 428.88. | |
| cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride | cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 267668-74-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C11H12ClN5O HCl, Molecular Weight: 265.7. US Biological Life Sciences. | Worldwide |
| cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride | cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride is an intermediate of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: (1R,4S)-rel-4-(2-Amino-6-chloro-9H-purin-9-yl)2-cyclopentene-1-methanol Hydrochloride. CAS No. 267668-74-6. Molecular formula: C11H12ClN5O HCl. Mole weight: 265.7. | |
| ent-Abacavir | ent-Abacavir (Abacavir EP Impurity A) is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Uses: Anti-hiv agents. Synonyms: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir; Abacavir EP Impurity A; Abacavir Impurities; Ent-Abacavir. Grades: 97%. CAS No. 136470-79-6. Molecular formula: C14H18N6O. Mole weight: 286.33. | |
| rac-Abacavir Sulfate | rac-Abacavir Sulfate is a racemic mixture of ent-Abacavir and Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: Abacavir Sulfate Racemic; (4-[2-Amino-6-(cyclopropylamino)-9H-purin-9yl]-2-cyclopentene-1-methanol Sulfate (2:1). Molecular formula: C28H38N12O6S. Mole weight: 670.47. | |
| trans-Abacavir Dihydrochloride | trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: (1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Diydrochloride. Grades: 98%. Molecular formula: C14H20Cl2N6O. Mole weight: 359.25. | |
| (1R,2S)-2-(Benzyloxy)methyl-3-cyclopenten-1-ol | A reactant used in the preparation of carbocyclic deoxyguanosine analog with potent and selective anti-hepatitis B virus. Group: Biochemicals. Alternative Names: (1R, 2S)-2-[ (Phenylmethoxy)methyl]-3-cyclopenten-1-ol; (1R-trans)-2-[ (Phenylmethoxy)methyl]-3-cyclopenten-1-ol. Grades: Highly Purified. CAS No. 188399-48-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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