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| Product | Description | |
|---|---|---|
| Carbonic anhydrase inhibitor 2 | Carbonic anhydrase inhibitor 1 (compound 7c) is a carbonic anhydrase II inhibitor. Carbonic anhydrase inhibitor 3 reduces the intraocular pressure in glaucomatous rabbits [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758231-43-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142849. |  |
| Carbonic anhydrase inhibitor 6 | An inhibitor of Carbonic anhydrase. Grade: 98%. CAS No. 1013213-84-7. Molecular formula: C26H25N3O5S. Mole weight: 491.6. |  |
| Carbonic Anhydrase IX/XII Inhibitor (CAIX Inhibitor) | A cell permeable benzenesulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (Ki = 0.9nM and 5.7nM, respectively) against two other physiologically relevant hCA isoforms (Ki = 23.4nM and 15nM for hCA I and hCA II, respectively), as compared with another CA inhibitor AAZ (Ki = 250nM, 12nM, 25nM, and 5.7nM for hCA I, hCA II, hCA IX, and hCA XII, respectively). It is shown to effectively inhibit the formation of metastases by 4T1 breast cancer cells in a mouse model dose-dependently at pharmacologic concentrations of 15-45mg/kg. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Carbonic Anhydrase IX/XII Inhibitor II, U-104 (CAIX Inhibitor II) | A cell permeable ureido-sulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (KiEnM and 4.5nM, respectively) against two other physiologically relevant hCA isoforms (KiP80nM and 9640nM for hCA I and hCA II, respectively). It elicits anti-tumor growth effects dose-dependently from 19 to 38mg/kg in a mouse tumor growth model implanted with MDA-MB-231 LM2-4Luc+ cells, and demonstrates metastasis inhibition in a mouse metastasis model injected with 4T1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1-(2-(Benzylthio)-5-chlorothiophen-3-yl)ethanone | Reagent used in the preparation of carbonic anhydrase inhibitors. Group: Biochemicals. Alternative Names: 1-[5-Chloro-2-[(phenylmethyl)thio]-3-thienyl]ethanone. Grades: Highly Purified. CAS No. 160982-09-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole | 1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole is a hypoxia-targeting carbonic anhydrase IX inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1383370-92-0. Pack Sizes: 100mg, 1g. Molecular Formula: C6H11N5O4S, Molecular Weight: 249.25. US Biological Life Sciences. | Worldwide |
| 1-Amino-3-Hydroxybenzene | 1-Amino-3-Hydroxybenzene is used in the preparation of inhibitors of mammalian carbonic anhydrase isoforms. Also used in the preparation of quinoline tethered fluorescent carbon dots for regulated anticancer discovery. Group: Biochemicals. Grades: Highly Purified. CAS No. 591-27-5. Pack Sizes: 10g, 50g. Molecular Formula: C6H7NO. US Biological Life Sciences. | Worldwide |
| 2,3-Difluorobenzoic Acid | 2,3-Difluorobenzoic acid is the difluorinated analogue of Benzoic acid (B203900). 2,3-Difluorobenzoic acid is a useful synthetic intermediate and is used as a starting material to synthesize thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV. Group: Biochemicals. Grades: Highly Purified. CAS No. 4519-39-5. Pack Sizes: 2.5g, 10 g. Molecular Formula: C7H4F2O2, Molecular Weight: 158.1. US Biological Life Sciences. | Worldwide |
| 2-(3-methoxypropyl)-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; 2-(3-methoxypropyl)-1,1-dioxothieno[3,2-e]thiazine-6-sulfonamide; B0464-284943; 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 171273-35-1. Molecular formula: C10H14N2O5S3. Mole weight: 338.42. | |
| 2-(3-Methoxypropyl)-4-oxo-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: 2-(3-Methoxypropyl)-4-oxo-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide; 3,4-Dihydro-2-(3-methoxypropyl)-4-oxo-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide. Grade: 98.0%. CAS No. 154127-41-0. Molecular formula: C10H14N2O6S3. Mole weight: 354.41. | |
| 2,4-Disulfamyl-5-trifluoromethylaniline | 2,4-Disulfamyl-5-trifluoromethylaniline is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug. Metabolite of hydroflumethazide, a diuretic. Group: Biochemicals. Grades: Highly Purified. CAS No. 654-62-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8F3N3O4S2. US Biological Life Sciences. | Worldwide |
| 2-Aminobenzenesulfonamide | 2-Aminobenzenesulfonamide is a potent inhibitor of carbonic anhydrase B. Synonyms: 2-aminobenzenesulfonamide. Grade: 98 %. CAS No. 3306-62-5. Molecular formula: C6H8N2O2S. Mole weight: 172.20. | |
| 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide | 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C10H16N2O4S3. US Biological Life Sciences. | Worldwide |
| 2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide | 2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide is an intermediate in the synthesis of 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide (D288235), which is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H18N2O5S3. US Biological Life Sciences. | Worldwide |
| 2-Hydroxyethanesulfonic Acid | 2-Hydroxyethanesulfonic Acid is a reactant in the synthesis of 4-substituted-2, 3, 5, 6-tetrafluorobene zene sulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. Group: Biochemicals. Grades: Highly Purified. CAS No. 107-36-8. Pack Sizes: 1g, 10g. Molecular Formula: C2H6O4S. US Biological Life Sciences. | Worldwide |
| 2-Methyl-5-nitrobenzenesulfonamide | 2-Methyl-5-nitrobenzenesulfonamide (CAS# 6269-91-6) is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonic anhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy. Synonyms: 2-methyl-5-nitrobenzenesulfonamide; 2-methyl-5-nitrobenzenesulfonamide. Grade: 98 %. CAS No. 6269-91-6. Molecular formula: C7H8N2O4S. Mole weight: 216.21. | |
| 2-Methyl-5-nitro Benzene sulfonamide | 2-Methyl-5-nitro Benzene sulfonamide is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonic anhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 6269-91-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8N2O4S, Molecular Weight: 216.21. US Biological Life Sciences. | Worldwide |
| 2-Nitro-benzenesulfonamide | 2-Nitro-benzenesulfonamide is a carbonic anhydrase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 5455-59-4. Pack Sizes: 1g, 5g. Molecular Formula: C6H6N2O4S, Molecular Weight: 202.19. US Biological Life Sciences. | Worldwide |
| 3-Acetyl-5-chloro-2-thiophenesulfonamide | 3-Acetyl-5-chloro-2-thiophenesulfonamide is a reactant used in the preparation of heteroaryl chalcones as potent antimicrobial agents and Brinzolamide (B677600), a topical carbonic anhydrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 160982-10-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 4-Acetylphenylboronic acid | 4-Acetylphenylboronic acid is a potent inhibitor of carbonic anhydrases II( CA II ), with IC 50 s of 246 μM and 281.40 μM for bovine CA II ( bCA II ) and human CA II ( hCA II ), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149104-90-5. Pack Sizes: 10 g. Product ID: HY-32933. | |
| 4-Acetylsulfanilamide-[13C6] | 4-Acetylsulfanilamide-[13C6] is the labelled analogue of 4-Acetylsulfanilamide, which has been used as an inhibitor of mitochondrial isoenzyme carbonic anhydrase V. Synonyms: 4-Acetylaminobenzene-13C6-sulfonamide; 4-Acetylsulfanilamide-13C6; 4-Acetamidobenzenesulfonamide-13C6; N4-Acetylsulfanilamide-(ring-13C6); N-(4-Sulfamoylphenyl)acetamide-13C6; p-Sulfamylacetanilide-13C6; 4'-Sulfamylacetanilide-13C6; p-Acetamidobenzenesulfonamide-13C6. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1655498-04-6. Molecular formula: C2[13C]6H10N2O3S. Mole weight: 220.20. | |
| 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide | 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide, a metabolite of the diuretic hydroflumethazide, is a carbonic anhydrase inhibitor that is used as a potential anti-tumor and anti-glaucoma drug. Synonyms: 2,4-Disulfamyl-5-trifluoromethylaniline; 2-Amino-4-trifluoromethyl-1,5-benzendisulfonamide; 1,3-Benzenedisulfonamide, 4-amino-6-(trifluoromethyl)-; NSC 44625; 2,4-Disulfamoyl-5-trifluoromethylaniline; 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide; 5-Amino-α,α,α-trifluorotoluene-2,4-disulfonamide. Grade: 95%. CAS No. 654-62-6. Molecular formula: C7H8F3N3O4S2. Mole weight: 319.28. | |
| 4-Desethylamino 4-oxobrinzolamide | 4-Desethylamino 4-oxobrinzolamide is an impurity of Brinzolamide (B677600), a carbonic anhydrase inhibitor and a antiglaucoma agent. Group: Biochemicals. Alternative Names: 3,4-Dihydro-2-(3-methoxypropyl)-4-oxo-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide. Grades: Highly Purified. CAS No. 154127-41-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (4R,6R)-Dorzolamide | (4R,?6R)?-Dorzolamide is an isomer of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour. Synonyms: 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6R)-; 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R-trans)-; 4R,6R-Dorzolamide; (+)-(Trans)-dorzolamide; ent-Dorzolamide; (4R-trans)-4-(ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide; Dorzolamide Impurity A (EP); Dorzolamide EP Impurity A. Grade: ≥95%. CAS No. 120279-95-0. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
| 4-Sulfamoylbenzoic acid | Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors. Uses: Carzenide could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors. Synonyms: 4-sulfamoylbenzoic acid. Grade: > 98 %. CAS No. 138-41-0. Molecular formula: C7H7NO4S. Mole weight: 201.20. | |
| 4-Tolylsulfonamide | 4-Tolylsulfonamide is a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs. Group: Biochemicals. Alternative Names: 4-Methyl Benzene sulfonamide; p-Toluenesulfonamide; 4-Methylbenzene-1-sulfonamide; 4-Methyl Benzene sulfonamide; 4- methyl benzensulfonamide; 4- methyl phenylsulfonamide; 4-Tolylsulfonamide; NSC 9908; Plasticizer 15; Toluene-4-sulfonamide; Tolylsulfonamide; Topcizer 1S; Tosylamide; Uniplex 173; p-Methyl Benzene sulfonamide; p-Tolylsulfonamide; p-Tosylamide. Grades: Highly Purified. CAS No. 70-55-3. Pack Sizes: 1g, 10g, 50g, 100g. Molecular Formula: C?H?NO?S, Molecular Weight: 171.22. US Biological Life Sciences. | Worldwide |
| 5-(Acetylimino)-4,5-dihydro-4-methyl-1,3,4-thiadiazole-2-sulfonic Acid | 5-(Acetylimino)-4,5-dihydro-4-methyl-1,3,4-thiadiazole-2-sulfonic Acid is a metabolite of the carbonic anhydrase inhibitor Methazolamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1312679-00-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 6-Ethoxy-2-benzothiazolesulfonamide | Ethoxzolamide is used in the treatment of glaucoma, and is also used as a diuretic, acting as a carbonic anhydrase inhibitor. Uses: Acting as a carbonic anhydrase inhibitor. Synonyms: 6-ethoxy-1,3-benzothiazole-2-sulfonamide. Grade: ≥ 98 %. CAS No. 452-35-7. Molecular formula: C9H10N2O3S2. Mole weight: 258.32. | |
| Acetazolamide | Acetazolamide is a carbonic anhydrase ( CA ) IX inhibitor with an IC 50 of 30 nM for hCA IX. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities [1] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59-66-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0782. | |
| Acetazolamide | Carbonic anhydrase inhibitor. Diuretic. Group: Biochemicals. Alternative Names: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide; Acetamox; Atenezol; Defiltran; Diamox; Didoc. Grades: Highly Purified. CAS No. 59-66-5. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Acetazolamide-13C2-d3 | Acetazolamide-13C2-d3 is a labelled Acetazolamide. Acetazolamide is a diuretic and a carbonic anhydrase inhibitor used for the treatment of glaucoma, epilepsy, nausea, idiopathic intracranial hypertension, etc. Synonyms: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-13C2-d3; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-13C2-d3; Acetamox-13C2-d3; Atenezol-13C2-d3. Grade: > 95%. Molecular formula: C4H3N4O3S2D3. Mole weight: 227.24. | |
| Acetazolamide-[d3] | The isotope labelled form of Acetazolamide which is an effective carbonic anhydrase inhibitor, could be used as a diuretic agent. Synonyms: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3; Acetamox-d3; Atenezol-d3; Defiltran-d3; Diamox-d3; Didoc-d3. Grade: >98%. CAS No. 1189904-01-5. Molecular formula: C4H3D3N4O3S2. Mole weight: 225.26. | |
| Acetazolamide-d3 (N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3, 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3, Acetamox-d3, Atenezol-d3, Defiltran-d3, Diamox-d3, Didoc-d3) | Carbonic anhydrase inhibitor. Diuretic. Group: Biochemicals. Alternative Names: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3; Acetamox-d3; Atenezol-d3; Defiltran-d3; Diamox-d3; Didoc-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Acetazolamide sodium | Acetazolamide sodium is a carbonic anhydrase ( CA ) IX inhibitor with an IC 50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities [1] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1424-27-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0782A. | |
| Amidosulfonic Acid | Amidosulfonic acid is mainly a precursor to sweet-tasting compounds. It has been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anti-cancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight loss drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 5329-14-6. Pack Sizes: 1g, 10g. Molecular Formula: H3NO3S. US Biological Life Sciences. | Worldwide |
| Benzenesulfonamide | Benzenesulfonamide ia an inhibitor of carbonic anhydrases. Synonyms: Benzenesulfonyl amine; Benzenesulphonamide; M and B 7973; NSC 5341; NSC 85506; Phenylsulfonamide. Grade: ≥95%. CAS No. 98-10-2. Molecular formula: C6H7NO2S. Mole weight: 157.19. | |
| Benzenesulphonamide | Benzenesulphonamide (compound 1) is a potent carbonic anhydrase inhibitor. Benzenesulphonamide shows CA II inhibitory activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98-10-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-101087. | |
| Benzolamide | Benzolamide (CL11366) is a potent carbonic anhydrase (CA) inhibitor, with K i s of 15 nM, 9 nM, 94 nM and 78 nM for hCA I , hCA II , EcoCAγ and VchCAγ , respectively. Benzolamide also inhibits CAS3 , with a K i of 54 nM. Benzolamide can be used for the research of glaucoma and seizures [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL11366. CAS No. 3368-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118467. | |
| Benzthiazide | Benzthiazide is a long-acting diuretic [1] and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9) , with K i s of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 91-33-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1424. | |
| Brinzolamide | Brinzolamide (AL-4862) is a selective carbonic anhydrase II inhibitor with an IC 50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide can be used in glaucoma disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AL-4862. CAS No. 138890-62-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0588. | |
| Brinzolamide | Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. Uses: Carbonic anhydrase inhibitors. Synonyms: AL-4862; AL 4862; AL4862; Brinzolamide; trade names Azopt, Alcon Laboratories, Befardin, Fardi Medicals. Grade: >98%. CAS No. 138890-62-7. Molecular formula: C12H21N3O5S3. Mole weight: 383.51. | |
| Brinzolamide-d5 | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-(Ethylamino-d5)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide; AL-4682-d5; Azopt-d5. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Brinzolamide-[d5] | Brinzolamide-[d5] is the labelled analogue of Brinzolamide. Brinzolamide is a carbonic anhydrase inhibitor used for the treatment of open-angle glaucoma and ocular hypertension. Synonyms: Brinzolamide D5; Brinzolamide-d5; (4R)-(Ethylamino-d5)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide; AL-4682-d5; Azopt-d5; (R)-4-((Ethyl-d5)amino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide. Grade: >95%. CAS No. 1217651-02-9. Molecular formula: C12H16D5N3O5S3. Mole weight: 388.54. | |
| Brinzolamide hydrochloride | Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. Synonyms: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide Hydrochloride; AL-4682 Hydrochloride; Azopt Hydrochloride. CAS No. 150937-43-2. Molecular formula: C12H22ClN3O5S3. Mole weight: 419.97. | |
| Brinzolamide Hydrochloride | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide Hydrochloride; AL-4682 Hydrochloride; Azopt Hydrochloride. Grades: Highly Purified. CAS No. 150937-43-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Brinzolamide maleate | A maleate salt of Brinzolamide. Brinzolamide is a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: Brinzolamide maleic acid adduct; 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-, (2Z)-2-butenedioate (1:1); (R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide maleate. Grade: ≥95%. CAS No. 1448780-04-8. Molecular formula: C12H21N3O5S3.C4H4O4. Mole weight: 499.58. | |
| CAIX Inhibitor S4 | CAIX Inhibitor S4 is an inhibitor of carbonic anhydrase IX. It is selective for CAIX over CAI and CAII but does inhibit CAXII. It reduced the number of lung metastases, but not primary tumor growth, in an MDA-MB-231 mouse xenograft model. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1330061-67-0. Molecular formula: C15H17N3O4S. Mole weight: 335.38. Purity: >98%. IUPACName: 4-(3-(3,5-dimethylphenyl)ureido)phenyl sulfamate. Canonical SMILES: O=S(OC[5]=CC=C(NC(NC[16]=CC(C)=CC(C)=C@16)=O)C=C@6)(N)=O. Product ID: ACM1330061670. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CAIX Inhibitor S4 | CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII (CA IX/XII), with a Ki of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I (Ki=546 and 5600 nM, respectively). CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1330061-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110243. | |
| Carbonic Anhydrase II from Human, Recombinant | Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30 kDa Da. The enzyme catalyzes the hydRation of carbon dioxide to carbonic acid. It is involved in vital processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, this enzyme is an important target for inhibitors with clinical applications in various pathologies such as glaucoma, epilepsy and Parkinsons disease. Applications: Human carbonic anhydrase isozyme ii has been used to assess its gene fusion abilities for efficient expression and recovery of recombinant proteins. human ...viduals. the enzyme has also been used in the study of natural phenolic inhibitors of ca ii. Group: Enzymes. Synonyms: Carbonic Anhydrase II; carbonate dehydRatase; carbonic anhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhydrase A; carbonate hydro-lyase; EC 4.2.1.1; CA-II; CA2; Carbonic Anhydrase 2. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. Carbonic Anhydrase. Activity: > 80%, > 3 ,000 W-A units/mg protein. Form: powder. Source: E. coli. Species: Human. Carbonic Anhydrase II; carbonate dehydRatase; carbonic anhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhyd |  |
| (+/-)-(cis)-Dorzolamide | (+/-)-(cis)-Dorzolamide is an isomer of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour. Synonyms: rac-cis Dorzolamide; (4R,6S)-rel-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide; cis-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide. CAS No. 120279-90-5. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
| Daidzein-[3',5',8-d3] | Daidzein-[3',5',8-d3] is the labelled analogue of Daidzein. Daidzein binds to estrogen receptor β but not ERα at concentrations up to 1 mM. And it is an inhibitor of carbonic anhydrase (CA) that is selective for carbonic CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively). Synonyms: Daidzein-3',5',8-D3; 7-Hydroxy-3-(4-hydroxyphenyl-3,5-d2)-4H-1-benzopyran-4-one-8-d; 4',7-Dihydroxyisoflavone-d3; Daidzein-d3. Grade: 97%; >98% by NMR atom D. CAS No. 220930-96-1. Molecular formula: C15H7D3O4. Mole weight: 257.26. | |
| Daidzein-[d4] | Daidzein-[d4], is the labelled analogue of Daidzein. Daidzein binds to estrogen receptor β but not ERα at concentrations up to 1 mM. And it is an inhibitor of carbonic anhydrase (CA) that is selective for carbonic CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively). Synonyms: Daidzein D4. Grade: 98% (CP); 99% atom D. CAS No. 1219803-57-2. Molecular formula: C15H6D4O4. Mole weight: 258.26. | |
| Daidzein-[d6] | Daidzein-[d6] is the labelled analogue of Daidzein. Daidzein binds to estrogen receptor β but not ERα at concentrations up to 1 mM. And it is an inhibitor of carbonic anhydrase (CA) that is selective for carbonic CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively). Uses: The labelled aglucon of daidzin. Synonyms: Daidzein D6; 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d6; 4',7-Dihydroxyisoflavone-d6; Daidzein-2',3',5',6,6',8-d6. Grade: 98%; ≥97% atom D. CAS No. 291759-05-2. Molecular formula: C15H4D6O4. Mole weight: 260.27. | |
| Dichlorphenamide | Dichlorphenamide (Diclofenamide) is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Diclofenamide. CAS No. 120-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0397. | |
| Dichlorphenamide | Dichlorphenamide is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class. Synonyms: Diclofenamide. Grade: >98%. CAS No. 120-97-8. Molecular formula: C6H6Cl2N2O4S2. Mole weight: 305.16. | |
| Diclofenamide | Diclofenamide is a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP). Group: Biochemicals. Alternative Names: 1,3-Disulfamoyl-4,5-dichlorobenzene; 1,3-Disulfamyl-4,5-dichlorobenzene; 3, 4-Dichloro-5-sulfamyl Benzene sulfonamide; 4,5-Dichloro-1,3-disulfamoylbenzene; 4,5-Dichloro-m-benzenedisulfonamide; Antidrasi; CB 8000; Daramide; Daranide; Dichlofenamide; Dichlorophenamide; Dichlorphenamide; Diclofenamid; Glaucol; Oratrol. Grades: Highly Purified. CAS No. 120-97-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Diclofenamide-[13C6] | Diclofenamide-[13C6] is a labelled Diclofenamide. Diclofenamide is a carbonic anhydrase inhibitor indicated for the treatment of glaucoma. Synonyms: Diclofenamide-13C6. Grade: 95% by HPLC; 95% atom 13C. CAS No. 1391054-76-4. Molecular formula: [13C]6H6Cl2N2O4S2. Mole weight: 311.11. | |
| Dimethylfraxetin | Dimethylfraxetin is a Carbonic anhydrase inhibitor, with a K i value of 0.0097 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 6,7,8-Trimethoxycoumarin; Fraxetin dimethyl ether. CAS No. 6035-49-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0085. | |
| Dorzolamide | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4S,6S)-. Grades: Highly Purified. CAS No. 130693-82-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Dorzolamide-[d5] | Dorzolamide-[d5] is the labelled analogue of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor used to lower the pressure of eyes with glaucoma. Synonyms: Dorzolamide D5; (4S,6S)-4-[(2H5)Ethylamino]-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide. Grade: 95% by HPLC; 95% atom D. CAS No. 1227097-70-2. Molecular formula: C10H11D5N2O4S3. Mole weight: 329.47. | |
| Dorzolamide-d5 hydrochloride | Dorzolamide-d5 is used as an internal standard for the quantification of dorzolamide by GC- or LC-MS. Dorzolamide is an inhibitor of carbonic anhydrase (CA), including CAII, CAV, CAVI, CAIX, CAXII, CAXIII, and CAXIV. Synonyms: L-671,152-d5; MK-507-d5; Trusopt-d5; (4S,6S)-4-((ethyl-d5)amino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide, monohydrochloride. Grade: ≥99% atom D. Molecular formula: C10H11D5N2O4S3·HCl. Mole weight: 365.93. | |
| Dorzolamide hydrochloride | Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC 50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L671152 hydrochloride; MK507 hydrochloride. CAS No. 130693-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 250 mg. Product ID: HY-B0109A. | |
| Dorzolamide Hydrochloride | Dorzolamide hydrochloride is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Synonyms: Dorzolamide HCl; TRUSOPT; (2S,4S)-2-Ethylamino-4-methyl-5,5-dioxo-5,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide hydrochloride; (4S-trans)-4-(ethylamino)-5,6-dihydro-6-methyl4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride. Grade: >98%. CAS No. 130693-82-2. Molecular formula: C10H17ClN2O4S3. Mole weight: 360.886. | |
| Dorzolamide Impurity A | Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Uses: Carbonic anhydrase inhibitors. Synonyms: L671152; MK507; L 671152; MK 507; L-671152; MK-507; Trusopt. Grade: >98%. CAS No. 120279-96-1. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
| Dorzolamide Maleic Acid Adduct | An impurity of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor primarily used to lower intraocular pressure in conditions such as glaucoma and ocular hypertension. Synonyms: N-Ethyl-N-((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)aspartic acid; 2-(Ethyl((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)succinic Acid; Dorzolamide Maleic Acid. Grade: ≥95%. Molecular formula: C14H20N2O8S3. Mole weight: 440.51. | |
| Doxylamine N-Oxide | An impurity of Dorzolamide. Dorzolamide is a topical carbonic anhydrase inhibitor used primarily to treat glaucoma and ocular hypertension. Synonyms: Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-, N-oxide; Doxylamine-N-Oxide; N,N-Dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethan-1-amine oxide. Grade: ≥95%. CAS No. 97143-65-2. Molecular formula: C17H22N2O2. Mole weight: 286.37. | |
| DTA | DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonic anhydrase [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,4-Disulfamyl-5-trifluoromethylaniline. CAS No. 654-62-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011293. | |
| DTP348 | DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP348 is an oral dual drug with two mechanisms of action: (1) carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2) radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety. Synonyms: DTP 348; DTP-348; 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylsulfamide; 1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole. CAS No. 1383370-92-0. Molecular formula: C6H11N5O4S. Mole weight: 249.24. | |
| Ethoxzolamide | Ethoxzolamide is a carbonic anhydrase inhibitor with Ki of 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Redupresin; L-643786; PNU-4191. CAS No. 452-35-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1480. | |
| Girentuximab | Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX) , a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: G250; cG250. CAS No. 916138-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99023. | |
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