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Acts on a wide range of carbonyl compounds, including quinones, aromatic aldehydes, ketoaldehydes, daunorubicin and prostaglandins E and F, reducing them to the corresponding alcohol. Si-specific with respect to NADPH [cf. EC 1.1.1.2 alcohol dehydrogenase (NADP+)]. Group: Enzymes. Synonyms: aldehyde reductase 1; prostaglandin 9-ketoreductase; xenobiotic ketone reductase; NADPH-dependent carbonylreductase; ALR3; carbonylreductase; nonspecific NADPH-dependent carbonylreductase; carbonylreductase (NADPH2). Enzyme Commission Number: EC 1.1.1.184. CAS No. 89700-36-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0086; carbonylreductase (NADPH); EC 1.1.1.184; 89700-36-7; aldehyde reductase 1; prostaglandin 9-ketoreductase; xenobiotic ketone reductase; NADPH-dependent carbonylreductase; ALR3; carbonylreductase; nonspecific NADPH-dependent carbonylreductase; carbonylreductase (NADPH2). Cat No: EXWM-0086.
R-CarbonylReductase (Crude Enzyme)
This product with the indicated enzyme activity was briefly purified from engineered E. coli, and can be used for NADH regeneration in biotechnology. Applications: Synthesis. Group: Enzymes. Synonyms: (S)-1-phenylethanol dehydrogenase; ADH; ADH1; ADH2; ADHTt; carbonylreductase (NADH, specific for (S)-configuration of alcohol); NAD + -dependent (S)-stereospecific alcohol dehydrogenase; PED; SADH; short-chain NAD(H)-dependent alcohol dehydrogenase; TtADH; CRII. Enzyme Commission Number: EC 1.1.1.B3. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. (S)-1-phenylethanol dehydrogenase; ADH; ADH1; ADH2; ADHTt; carbonylreductase (NADH, specific for (S)-configuration of alcohol); NAD + -dependent (S)-stereospecific alcohol dehydrogenase; PED; SADH; short-chain NAD(H)-dependent alcohol dehydrogenase; TtADH; CRII. Pack: 100ml. Cat No: NATE-1788.
S-CarbonylReductase (Crude Enzyme)
This product with the indicated enzyme activity was briefly purified from engineered E. coli, and can be used for NADH regeneration in biotechnology. Applications: Synthesis. Group: Enzymes. Synonyms: ADH; ADH1; ADH2; ADHTt; carbonylreductase (NADH, specific for (S)-configuration of alcohol); short-chain NAD(H)-dependent alcohol dehydrogenase. Enzyme Commission Number: EC 1.1.1.B4. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. ADH; ADH1; ADH2; ADHTt; carbonylreductase (NADH, specific for (S)-configuration of alcohol); short-chain NAD(H)-dependent alcohol dehydrogenase. Pack: 100ml. Cat No: NATE-1789.
10-trans-Atorvastatin Acetonide tert-Butyl Ester
10-trans-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4S,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1105067-90-0. Molecular formula: C40H47FN2O5. Mole weight: 654.81.
1- (4-Trifluoromethylphenyl) pentan-1-one
1- (4-Trifluoromethylphenyl) pentan-1-one is a derivative of Valerophenone (V091450); an inhibitor of the enzyme carbonylreductase. 1- (4-Trifluoromethylphenyl) pentan-1-one is also used as a reagent in the synthesis of 5,5-diarylpentadienamides as orally available TRPV1 antagonists for treatment of neuropathic pain. Group: Biochemicals. Grades: Highly Purified. CAS No. 42916-66-5. Pack Sizes: 250mg, 2.5 g. Molecular Formula: C12H13F3O, Molecular Weight: 230.23. US Biological Life Sciences.
2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid is an intermediate useful in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1391194-36-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C33H33FN2O5, Molecular Weight: 556.62. US Biological Life Sciences.
2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 947262-20-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C37H41FN2O5, Molecular Weight: 612.73. US Biological Life Sciences.
Worldwide
2-Fluoro Atorvastatin tert-Butyl Ester
2-Fluoro Atorvastatin tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6R)-6-(2-(2-(2-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6R)-6-[2-[2-(2-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1099474-28-8. Molecular formula: C40H47FN2O5. Mole weight: 654.81.
(3R,5S)-Atorvastatin Acetonide tert-Butyl Ester
(3R,5S)-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl 1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl (4R,6S)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 947249-30-1. Molecular formula: C40H47FN2O5. Mole weight: 654.81.
(3S,5S)-Atorvastatin sodium salt
Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective against hypercholesterolemia and certain dyslipidemias. Synonyms: 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, monosodium salt; 3S,5S-Atorvastatin Sodium; sodium (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate. Grades: ≥98%. CAS No. 1428118-38-0. Molecular formula: C33H34FN2O5·Na. Mole weight: 580.6.
(3S,5S)-Atorvastatin Sodium Salt
A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βS,δS)-2-(4-Fluorophenyl)- β , δ -dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium; 3S,5S-Atorvastatin Sodium. Grades: Highly Purified. CAS No. 501121-34-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C33H34FN2NaO5, Molecular Weight: 580.62. US Biological Life Sciences.
Worldwide
4-Hydroxy Atorvastatin Calcium Salt
4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βR,δR)-2-(4-Fluorophenyl)- β , δ -dihydroxy-4-[[ (4-hydroxyphenyl) amino]carbonyl]-5- (1-methylethyl) -3-phenyl-1H-pyrrole-1-heptanoic Acid Calcium Salt; p-Hydroxyatorvastatin. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Aldose reductase from Human, Recombinant
In enzymology, aldose reductase (or aldehyde reductase) (EC 1.1.1.21) is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides. It is primarily known for catalyzing the reduction of glucose to sorbitol, the first step in polyol pathway of glucose metabolism. Group: Enzymes. Synonyms: Aldehyde reductase; Aldo-keto reductase family 1 member B1. Enzyme Commission Number: EC 1.1.1.21. CAS No. 9028-31-3. Aldose reductase. Mole weight: 35853.4 Da. Source: Human. Aldehyde reductase; Aldo-keto reductase family 1 member B1; EC 1.1.1.21; Aldose reductase. Cat No: NATE-1198.
Atorvastatin 3-Deoxyhept-2E-Enoic Acid
Atorvastatin 3-Deoxyhept-2E-Enoic Acid is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (S,E)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-5-hydroxyhept-2-enoic acid; Atorvastatin 3-deoxyhept-2-enoic acid; (2E)-2,3-Dehydroxy Atorvastatin; 2-Heptenoic acid, 7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-, (2E,5S)-; (2E,5S)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-2-heptenoic acid. Grades: ≥95%. CAS No. 1105067-93-3. Molecular formula: C33H33FN2O4. Mole weight: 540.64.
Atorvastatin Calcium
A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βR,δR)-2-(4-Fluorophenyl)- β , δ -dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; Atorvastatin Hemicalcium; CI 981; Lipitor; Sortis; Tahor; YM 548. Grades: Highly Purified. CAS No. 134523-03-8. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C??H??CaF?N?O??, Molecular Weight: 1155.34. US Biological Life Sciences.
Worldwide
Atorvastatin EP Impurity B
Atorvastatin EP Impurity B is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3RS,5SR)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic Acid; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-; 2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid; Atorvastatin Calcium Impurity B; Atorvastatin calcium trihydrate impurity B [EP]. Grades: ≥95%. CAS No. 842103-12-2. Molecular formula: C33H35FN2O5. Mole weight: 558.65.
Atorvastatin EP Impurity C
Atorvastatin EP Impurity C is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[2,3-bis(4-fluorophenyl)-5-(1-methylethyl)-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; Fluoroatorvastatin; (3R,5R)-7-(2,3-Bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid; Difluoro Atorvastatin; Atorvastatin Impurity C; Atorvastatin calcium trihydrate impurity C [EP]; 1H-Pyrrole-1-heptanoic acid, 2,3-bis(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-, (βR,δR)-; (βR,δR)-2,3-Bis(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid. Grades: ≥95%. CAS No. 693794-20-6. Molecular formula: C33H34F2N2O5. Mole weight: 576.63.
Atorvastatin EP Impurity F
Atorvastatin EP Impurity F is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl]amino]-3,5-dihydroxyheptanoic acid; Atorvastatin EP Impurity F; Atorvastatin calcium trihydrate impurity F [EP]; Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)-; (3R,5R)-7-((3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic acid; Atorvastatin diamino [USP impurity]; Atorvastatin amide. Grades: ≥95%. CAS No. 887196-24-9. Molecular formula: C40H48FN3O8. Mole weight: 717.82.
Atorvastatin EP Impurity G
Atorvastatin EP Impurity H is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-5-hydroxy-3-methoxyheptanoic acid; 3-O-Methylatorvastatin; Atorvastatin Impurity G; Atorvastatin calcium trihydrate impurity G [EP]; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-δ-hydroxy-β-methoxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-; (βR,δR)-2-(4-Fluorophenyl)-δ-hydroxy-β-methoxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid; (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxy-3-methoxyheptanoic acid. Grades: ≥95%. CAS No. 887324-53-0. Molecular formula: C34H37FN2O5. Mole weight: 572.67.
Atorvastatin epoxy pyrrolooxazin 7-hydroxy analog
Atorvastatin epoxy pyrrolooxazin 7-hydroxy analog is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R)-4-(1b-(4-Fluorophenyl)-7-hydroxy-7-isopropyl-1a-phenyl-7a-(phenylcarbamoyl)hexahydro-1aH-oxireno[2',3':3,4]pyrrolo[2,1-b][1,3]oxazin-3-yl)-3-hydroxybutanoic acid; (3R)-4-[1b-(4-Fluorophenyl)-7-hydroxy-7-isopropyl-1a-phenyl-7a-(phenylcarbamoyl)hexahydro-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazin-3-yl]-3-hydroxybutanoic acid; 3H-Oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid, 1b-(4-fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-, (βR)-. Grades: ≥95%. Molecular formula: C33H35FN2O7. Mole weight: 590.64.
Atorvastatin Ethyl Ester
Atorvastatin Ethyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: (3R,5R)-Ethyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, ethyl ester, (βR,δR)-; Ethyl (βR,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate; Ethyl (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate. Grades: ≥95%. CAS No. 1146977-93-6. Molecular formula: C35H39FN2O5. Mole weight: 586.71.
Atorvastatin, Free Acid
Atorvastatin is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Atorvastatin 10 mg daily is safe and efficacious in reducing the risk of first cardiovascular disease events, including stroke. Group: Biochemicals. Alternative Names: Lipitor; Tozalip; Torvast; Cardyl; Atorvastatin acid; (3R,5R)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-yl-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid; 2-(4-fluorophenyl)- βR, δ R-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid. Grades: Highly Purified. CAS No. 134523-00-5. Pack Sizes: 1g. Molecular Formula: C33H35FN2O5, Molecular Weight: 558.64. US Biological Life Sciences.
Worldwide
Atorvastatin Lactam Impurity
Atorvastatin Lactam Impurity is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[5-(4-Fluorophenyl)-3-isopropyl-2-oxo-4-phenyl-3-(phenylcarbamoyl)-2,3-dihydro-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; Atorvastatin Pyrrolidone Analog (USP); 1H-Pyrrole-1-heptanoic acid, 5-(4-fluorophenyl)-2,3-dihydro-β,δ-dihydroxy-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-, (βR,δR)-; (βR,δR)-5-(4-Fluorophenyl)-2,3-dihydro-β,δ-dihydroxy-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid; (3R,5R)-3,5-Dihydroxy-7-[2-oxo-3-isopropyl-3-(phenylcarbamoyl)-4-phenyl-5-(4-fluorophenyl)-2,3-dihydro-1H-pyrrole-1-yl]heptanoic acid; Atorvastatin EP Impurity Q. Grades: ≥95%. CAS No. 906552-18-9. Molecular formula: C33H35FN2O6. Mole weight: 574.65.
Atorvastatin Lactam Phenanthrene Methyl Ester. (Mixture of Diastereomers)
Atorvastatin Lactam Phenanthrene Methyl Ester is an impurity of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Group: Biochemicals. Alternative Names: ( βR,δR)-9-Fluoro-2,3-dihydro- β , δ -dihydroxy-3- (1-methylethyl)-2-oxo-3-[ (phenylamino)carbonyl]-1H-dibenz[e, g]indole-1-heptanoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 906552-20-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Atorvastatin Methyl Ester
Atorvastatin Methyl Ester is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Methyl Ester; (3R,5R)-Methyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbaMoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, methyl ester, (βR,δR)-; Methyl (βR,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate. Grades: ≥95%. CAS No. 345891-62-5. Molecular formula: C34H37FN2O5. Mole weight: 572.68.
Atorvastatin tert-Butyl Ester
Atorvastatin tert-Butyl Ester is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, 1,1-dimethylethyl ester, (βR,δR)-; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, 1,1-dimethylethyl ester, [R-(R*,R*)]-; (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid tert-butyl ester. Grades: ≥95%. CAS No. 134395-00-9. Molecular formula: C37H43FN2O5. Mole weight: 614.76.
Atorvastatin USP Related Compound A
Atorvastatin USP Related Compound A is an impurity in the synthesis of Atorvastatin, which is a competitive HMG-CoA reductase inhibitor. Atorvastatin is a lipid-lowering medication of the statin class. Atorvastatin suppresses the production of cholesterol and prevents some cardiovascular diseases. Synonyms: Calcium (3R,5R)-7-[2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); Atorvastatin Desfluoro impurity; (3R,5R)-7-[3-(phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoicacid, calcium salt; USP Atorvastatin Related Compound A; Defluoro Atorvastatin Calcium Salt; Atorvastatin Related Compound A; Calcium (3R,5R)-3,5-dihydroxy-7-(2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl)heptanoate; 1H-Pyrrole-1-heptanoic acid, β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-; Calcium (βR,δR)-β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2). Grades: ≥95%. CAS No. 433289-83-9. Molecular formula: C66H70CaN4O10. Mole weight: 1119.38.
Atorvastatin USP Related Compound B
Atorvastatin USP Related Compound B is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3S,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (3S,5R)-Atorvastatin; Atorvastatin 3S,5R Isomer; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βS,δR)-; (βS,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid. Grades: ≥95%. CAS No. 887324-52-9. Molecular formula: C33H35FN2O5. Mole weight: 558.64.
benzil reductase [(R)-benzoin forming]
The enzyme from the bacterium Xanthomonas oryzae is able to reduce enantioselectively only one of the two carbonyl groups of benzil to give optically active (R)-benzoin. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.321. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0234; benzil reductase [(R)-benzoin forming]; EC 1.1.1.321. Cat No: EXWM-0234.
(βS,δS)-Atorvastatin tert-Butyl Ester
(βS,δS)-Atorvastatin tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: (3S,5S)-tert-butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 2-Methyl-2-propanyl (3S,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate; (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester. CAS No. 1428118-12-0. Molecular formula: C37H43FN2O5. Mole weight: 614.75.
cyclohexa-1,5-dienecarbonyl-CoA hydratase
Forms part of the anaerobic benzoate degradation pathway, which also includes EC 1.3.8.6 [glutaryl-CoA dehydrogenase (ETF)], EC 1.3.7.8 (benzoyl-CoA reductase) and EC 4.2.1.55 (3-hydroyxbutyryl-CoA dehydratase). Group: Enzymes. Synonyms: cyclohexa-1,5-diene-1-carbonyl-CoA hydratase; dienoyl-CoA hydratase; cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase (incorrect); 6-hydroxycyclohex-1-enecarbonyl-CoA hydro-lyase (cyclohexa-1,5-dienecarbonyl-CoA-forming). Enzyme Commission Number: EC 4.2.1.100. CAS No. 214355-79-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4940; cyclohexa-1,5-dienecarbonyl-CoA hydratase; EC 4.2.1.100; 214355-79-0; cyclohexa-1,5-diene-1-carbonyl-CoA hydratase; dienoyl-CoA hydratase; cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase (incorrect); 6-hydroxycyclohex-1-enecarbonyl-CoA hydro-lyase (cyclohexa-1,5-dienecarbonyl-CoA-forming). Cat No: EXWM-4940.
Defluoro Atorvastatin Calcium Salt
Desfluoro Atorvastatin is an impurity in the synthesis of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βR,δR)- β , δ -Dihydroxy-2- (1-methylethyl)-4, 5-diphenyl-3-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1). Grades: Highly Purified. CAS No. 433289-83-9. Pack Sizes: 5mg. Molecular Formula: C??H??CaN?O??, Molecular Weight: 1119.36. US Biological Life Sciences.
Worldwide
Difluoro Atorvastatin Acetonide tert-Butyl Ester
Difluoro Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6R)-6-(2-(2,3-bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6R)-6-[2-[2,3-Bis(4-fluorophenyl)-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 693793-87-2. Molecular formula: C40H46F2N2O5. Mole weight: 672.8.
ethyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: RYW6GR2YSQ; UNII-RYW6GR2YSQ; 616201-27-5; 1,3-Dioxane-4-acetic acid, 6-(2-(2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-, ethyl ester, (4R,6R)-; Ethyl (4R,6R)-6-(2-(2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxane-4-acetate; SCHEMBL915488. CAS No. 616201-27-5. Molecular formula: C38H43FN2O5. Mole weight: 626.77.
Finasteride Carboxylic Acid
An impurity of Finasteride. Finasteride is a 4-azasteroid analog of testosterone that competitively blocks type II 5α-reductase activity with 100-fold greater affinity than for the type I enzyme. Synonyms: 2-Methyl-N-[[(5α,17β)-3-oxo-4-azaandrost-1-en-17-yl]carbonyl]alanine. Grades: > 95%. CAS No. 116285-37-1. Molecular formula: C23H34N2O4. Mole weight: 402.54.
heme oxygenase (biliverdin-producing)
This mammalian enzyme participates in the degradation of heme. The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules. The third oxygen molecule provides the oxygen atom that converts the α-carbon to CO. The enzyme requires NAD(P)H and EC 1.6.2.4, NADPH-hemoprotein reductase. cf. EC 1.14.15.20, heme oxygenase (biliverdin-producing, ferredoxin). Group: Enzymes. Synonyms: ORP33 proteins; haem oxygenase (ambiguous); heme oxygenase (decyclizing) (ambiguous); heme oxidase (ambiguous); haem oxidase (ambiguous); heme oxygenase (ambiguous); heme,hydrogen-donor:oxygen oxidoreductase (α-methene-oxidizing, hydroxylating). Enzyme Commission Number: EC 1.14.14.18. CAS No. 9059-22-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0915; heme oxygenase (biliverdin-producing); EC 1.14.14.18; 9059-22-7; ORP33 proteins; haem oxygenase (ambiguous); heme oxygenase (decyclizing) (ambiguous); heme oxidase (ambiguous); haem oxidase (ambiguous); heme oxygenase (ambiguous); heme,hydrogen-donor:oxygen oxidoreductase (α-methene-oxidizing, hydroxylating). Cat No: EXWM-0915.
heme oxygenase (biliverdin-producing, ferredoxin)
The enzyme, found in plants, algae, and cyanobacteria, participates in the biosynthesis of phytochromobilin and phytobilins. The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules. The third oxygen molecule provides the oxygen atom that converts the α-carbon to CO. Unlike this enzyme, which uses ferredoxin as its electron donor, the electron source for the related mammalian enzyme (EC 1.14.14.18) is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: HO1 (gene name); HY1 (gene name); HO3 (gene name); HO4 (gene name); pbsA1 (gene name). Enzyme Commission Number: EC 1.14.15.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0945; heme oxygenase (biliverdin-producing, ferredoxin); EC 1.14.15.20; HO1 (gene name); HY1 (gene name); HO3 (gene name); HO4 (gene name); pbsA1 (gene name). Cat No: EXWM-0945.
isopropyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1-methylethyl ester, (4R,6R)-; propan-2-yl 2-[(4R,6R)-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate; Isopropyl Acetonide Atorvastatin; SCHEMBL12665703; DTXSID601099894; 1-Methylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 1112262-71-1. Molecular formula: C39H45FN2O5. Mole weight: 640.78.
L-xylulose reductase
Dicarbonyl/L-xylulose reductase, also known as carbonylreductase II, is an enzyme that in human is encoded by the DCXR gene located on chromosome 17. DCSR catalyzes the reduction of several L-xylylose as well as a number of pentoses, tetroses, trioses, alpha-dicarbonyl compounds. The enzyme is involved in carbohydrate metabolism, glucose metabolism, the uronate cycle and may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol. Group: Enzymes. Synonyms: xylitol dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.10. CAS No. 9028-17-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0002; L-xylulose reductase; EC 1.1.1.10; 9028-17-5; xylitol dehydrogenase (ambiguous). Cat No: EXWM-0002.
o-Hydroxy Atorvastatin, Dihydrate Monosodium Salt
A metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βR,δR)-2-(4-Fluorophenyl)- β , δ -dihydroxy-4-[[ (2-hydroxyphenyl) amino]carbonyl]-5- (1-methylethyl) -3-phenyl-1H-pyrrole-1-heptanoic Acid Dihydrate Monosodium Salt;BMS 243887-01; PD 152873; o-Hydroxyatorvastatin Dihydrate Monosodium Salt. Grades: Highly Purified. CAS No. 1421760-64-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
p-Hydroxy Atorvastatin, Disodium Salt
A metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βR,δR)-2-(4-Fluorophenyl)- β , δ -dihydroxy-4-[[ (4-hydroxyphenyl) amino]carbonyl]-5- (1-methylethyl) -3-phenyl-1H-pyrrole-1-heptanoic Acid Disodium Salt; BMS 241423-01; PD 142542; p-Hydroxyatorvastatin Disodium Salt. Grades: Highly Purified. CAS No. 1276537-18-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
prostaglandin-F synthase
Reduces prostaglandin D2 and prostaglandin H2 to prostaglandin F2; prostaglandin D2 is not an intermediate in the reduction of prostaglandin H2. Also catalyses the reduction of a number of carbonyl compounds, such as 9,10-phenanthroquinone and 4-nitroacetophenone. Group: Enzymes. Synonyms: prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Enzyme Commission Number: EC 1.1.1.188. CAS No. 55976-95-9. PGF synthetase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0090; prostaglandin-F synthase; EC 1.1.1.188; 55976-95-9; prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Cat No: EXWM-0090.
tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 2-Methyl-2-propanyl {(4R,6R)-6-[2-({[(4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetyl}amino)ethyl]-2,2-dimethyl-1,3-d ioxan-4-yl}acetate; 1,1-Dimethylethyl (4R,6R)-6-[2-[[2-[(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetyl]amino]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 1116118-82-1. Molecular formula: C50H64FN3O8. Mole weight: 854.06.
Valerophenone
Valerophenone is an aromatic ketone that is often used as a tool in the study of various photochemical processes. It is also an inhibitor of the enzyme carbonylreductase. Uses: Benzylhexahydropyrrolo[3,2-b]pyrrole-1(2h)-carboxylate (cas# 1251009-14-9) is a useful research chemical. Synonyms: 1-phenylpentan-1-one. Grades: > 95 %. CAS No. 1009-14-9. Molecular formula: C11H14O. Mole weight: 162.23.
Valerophenone
Valerophenone is an aromatic ketone that is often used as a tool in the study of various photochemical processes. Valerophenone is also an inhibitor of the enzyme carbonylreductase. Group: Biochemicals. Alternative Names: 1-Phenyl-1-pentanone; Butyl Phenyl Ketone; NSC 58959; Pentanophenone; Phenyl Butyl Ketone; n-Butyl Phenyl Ketone; n-Valerophenone. Grades: Highly Purified. CAS No. 1009-14-9. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
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