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| Product | Description | |
|---|---|---|
| Carfilzomib | Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Alternative Names: (α S) -α - [ [2- (4-Morpholinyl) acetyl] amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyl-2-oxiranyl] carbonyl] butyl] -L-phenylalaninamide; (α S) -α - [ (4-Morpholinylacetyl) amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyloxiranyl] carbonyl] butyl] -L-phenylalaninamide; PR 171. Grades: Highly Purified. CAS No. 868540-17-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C40H57N5O7, Molecular Weight: 719.91. US Biological Life Sciences. |  Worldwide |
| Carfilzomib | Carfilzomib is a tetrapeptide epoxyketone and an analog of epoxomicin, acting as a selective proteasome inhibitor, such as the chymotrypsin-like β5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and the β5i subunit of the immunoproteasome 20Si (LMP7; IC50 = 14 nM). It has been used as an injectable antineoplastic agent (IV only). Synonyms: Kyprolis; PR171; PR-171; PR 171; (2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide. Grades: ≥98%. CAS No. 868540-17-4. Molecular formula: C40H57N5O7. Mole weight: 719.9. |  |
| Carfilzomib | Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC 50 of 5 nM in ANBL-6 and RPMI 8226 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PR-171. CAS No. 868540-17-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10455. |  |
| Carfilzomib-d8 | Carfilzomib-d8. Group: Biochemicals. Alternative Names: (α S) -α - [ [2- (4-Morpholinyl) acetyl] amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyl-2-oxiranyl] carbonyl] butyl] -L-phenylalaninamide-d8; (α S) -α - [ (4-Morpholinylacetyl) amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyloxiranyl] carbonyl] butyl] -L-phenylalaninamide-d8; PR 171-d8. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C40H49D8N5O7, Molecular Weight: 727.96. US Biological Life Sciences. | Worldwide |
| Carfilzomib Impurity 13 hydrochloride | Carfilzomib is an anti-cancer drug acting as a selective proteasome inhibitor. Chemically, it is a tetrapeptide epoxyketone and an analog of epoxomicin. It is a second-generation and peptide epoxyketone class proteasome inhibitor that targets the chymotrypsin-like β5 subunit of the constitutive 20S proteasome with IC50 of 5.2 nM. Carfilzomib impurity 13 hydrochloride is a potential impurity found in commercial carfilzomib preparations. Grades: ≥95%. CAS No. 2319881-95-1. Molecular formula: C16H22N2O4·HCl. Mole weight: 342.8. | |
| Carfilzomib Impurity 18 | Carfilzomib Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1541171-67-8. Molecular formula: C40H58ClN5O7. Mole weight: 756.37. Catalog: APB1541171678. |  |
| Carfilzomib Impurity 2 | Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib , a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Synonyms: (α S) ?-α -[[2- (4-Morpholinyl) ?acetyl]?amino]?benzenebutanoyl-L-leucyl-N-[ (1S, ?3R) ?-3, ?4-dihydroxy-3-methyl-1- (2-methylpropyl) ?-2-oxobutyl]?-L-phenylalaninamide. Grades: > 95%. CAS No. 1541172-75-1. Molecular formula: C40H59N5O8. Mole weight: 737.94. | |
| Carfilzomib Impurity 27 | Carfilzomib Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. CAS No. 1672698-88-2. Molecular formula: C40H57N5O7. Mole weight: 719.91. Catalog: APB1672698882. | |
| Carfilzomib Impurity 39 | Carfilzomib Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-((S)-1-(((2R,4S)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. CAS No. 1541172-75-1. Molecular formula: C40H59N5O8. Mole weight: 737.93. Catalog: APB1541172751. | |
| Carfilzomib Impurity 39 | Carfilzomib Impurity 39. Uses: For analytical and research use. Group: Impurity standards. CAS No. 168154-76-5. Molecular formula: C10H12ClNO3. Mole weight: 229.66. Catalog: APB168154765. | |
| Carfilzomib Impurity 46 | Carfilzomib Impurity 46. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396006-47-5. Molecular formula: C22H33N3O5. Mole weight: 419.52. Catalog: APB1396006475. | |
| Carfilzomib Impurity 7 | Carfilzomib Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-4-methylpentanamido)-3-phenylpropanoate. CAS No. 15136-32-0. Molecular formula: C21H32N2O5. Mole weight: 392.49. Catalog: APB15136320. | |
| Carfilzomib Related Impurity ((S)-2-amino-4-oxo-4-phenylbutanoic acid hydrochloride) | (S)-4-Oxo-homophenylalanine Hydrochloride is a derivative of L-Homophenylalanine; an antitumor agent. Synonyms: (αS)-α-Amino-γ-oxo-benzenebutanoic Acid Hydrochloride; (S)-α-Amino-γ-oxo-benzenebutanoic Acid Hydrochloride. Grades: > 95%. CAS No. 168154-76-5. Molecular formula: C10H11NO3. HCl. Mole weight: 193.20 36.46. | |
| (2R)-2-Amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]pentan-1-one Trifluoroacetate Salt | (2R)-2-Amino-4-methyl-1-(2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt s an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences. | Worldwide |
| (2R,4S)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl | (2R,4S)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl is an intermediate used in the synthesis of Carfilzomib (2S,4S)-Diol (C183495), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 1541172-78-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H27NO5, Molecular Weight: 289.37. US Biological Life Sciences. | Worldwide |
| (2R,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate | (2R,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate is an intermediate in synthesizing Carfilzomib (2S,4S)-Diol (C183495), a derivative of Carflizomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H29NO6, Molecular Weight: 331.4. US Biological Life Sciences. | Worldwide |
| (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate | (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 247068-85-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences. | Worldwide |
| (2S,4R)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl | (2S,4R)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl is an intermediate used in the synthesis of Carfilzomib (2S,4R)-Diol (C183500), is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H27NO5, Molecular Weight: 289.37. US Biological Life Sciences. | Worldwide |
| (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate | (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate is an intermediate in synthesizing Carfilzomib (2S,4R)-Diol (C183500), a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H29NO6, Molecular Weight: 331.4. US Biological Life Sciences. | Worldwide |
| (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt | (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt is an intermediate in synthesizing Carfilzomib (2S,4R)-Diol (C183500), a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H21NO4; (C2HF3O2), Molecular Weight: 231.2911402. US Biological Life Sciences. | Worldwide |
| (2S,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate TFA Salt | (2S,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate TFA Salt is an intermediate used in the synthesis of Carfilzomib (2S,4S)-Diol (C183495), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C11H21NO4; C2HF3O2, Molecular Weight: 231.2911402. US Biological Life Sciences. | Worldwide |
| (2S,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate | (2S,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate is an intermediate in synthesizing Carfilzomib (2S,4S)-Diol (C183495), a derivative of Carflizomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H29NO6, Molecular Weight: 331.4. US Biological Life Sciences. | Worldwide |
| CFLZ-171 formic acid salt | CFLZ-171 is an important intermediate to synthesis carfilzomib which is an anti-cancer drug acting as a selective proteasome inhibitor. Synonyms: CFLZ-171 formic acid salt; CFLZ 171 formic acid salt; CFLZ171 formic acid salt; carfilzomib intermediate molecule weight 171. 1Pentanone 2amino4methyl1(2R)2methyl2oxiranyl (2S) 222trifluoroacetate (1:1); 1Pentanone 2amino4methyl1(2R)2methyloxiranyl (2S) trifluoroacetate (9CI);S)-2-amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one 2,2,2-trifluoroacetate. Grades: 98%. CAS No. 1140908-93-5. Molecular formula: C9H17NO2.CH2O2. Mole weight: 217.27. | |
| CFLZ-567 | CFLZ-567 is a key intermediate for making carfilzomib. carfilzomib is a selective proteasome inhibitor as an anti-cancer drug. Uses: Key intermediate for making carfilzomib. Synonyms: carfilzomib intermediate molecule weight 567; LPhenylalanine (S) 2 (4morpholinyl) acetylaminobenzenebutanoylLleucyl; LPhenylalanine (S) (4morpholinylacetyl) aminobenzenebutanoylLleucyl (9CI);(S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic acid. Grades: 98%. CAS No. 868540-16-3. Molecular formula: C31H42N4O6. Mole weight: 566.69. | |
| HRS-4642 | HRS-4642 is a selective KRAS(G12D) inhibitor (Kd=0.083 nM) with anti-cancer activity. HRS-4642 synergizes with Carfilzomib (HY-10455) and exhibits significant in vivo potency to reshape the tumor microenvironment into an immune-activating microenvironment. Uses: Scientific research. Group: Signaling pathways. CAS No. 2836263-09-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159127. | |
| (S)-2-Amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one 2,2,2-trifluoroacetate | An intermediate of Carfilzomib, which is a second-generation proteasome inhibitor for the treatment of relapsed and refractory multiple myeloma. Synonyms: 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-, (2S)-, 2,2,2-trifluoroacetate (1:1); 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyloxiranyl]-, (2S)-, trifluoroacetate; (2R)-2-[(2S)-2-Amino-4-methylpentanoyl]-2-methyloxirane trifluoroacetate; (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate; (2S)-2-Amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-pentanone 2,2,2-Trifluoroacetate. Grades: ≥95%. CAS No. 247068-85-5. Molecular formula: C9H17NO2.C2HF3O2. Mole weight: 285.26. | |
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