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| Product | Description | |
|---|---|---|
| Celecoxib | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14F3N3O2S. CAS No. 169590-42-5. Prepack ID 70641057-25mg. Molecular Weight 381.37. See USA prepack pricing. |  |
| Celecoxib | 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. anticholinergic. CAS No. 169590-42-5. Product ID: 8-04791. Molecular formula: C17H14F3N3O2S. Mole weight: 381.37. Purity: ≥98%. |  |
| Celecoxib | Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC 50 of 40 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 58635. CAS No. 169590-42-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-14398. |  |
| Celecoxib | Celecoxib is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Celebra; Celebrex; SC 58635; Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; Celecox; Celocoxib; Eurocox; Medicoxib; Onsenal; Xilebao; YM 177. Grades: ≥95%. CAS No. 169590-42-5. Molecular formula: C17H14F3N3O2S. Mole weight: 381.37. |  |
| Celecoxib carboxylic acid | Celecoxib carboxylic acid. Group: Biochemicals. Alternative Names: 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic acid; Celebrex carboxylic acid. Grades: Highly Purified. CAS No. 170571-01-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H12F3N3O4S. US Biological Life Sciences. |  Worldwide |
| Celecoxib Carboxylic Acid-Acyl-beta-D-Glucuronide | Celecoxib Carboxylic Acid Acyl-β-D-glucuronide is a glucuronide metabolite of Celecoxib, a Cox-2 inhibitor. Synonyms: 1-[4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoate] b-D-glucopyranuronic Acid. Grades: > 95%. CAS No. 264236-79-5. Molecular formula: C23H20F3N3O10S. Mole weight: 587.48. | |
| Celecoxib Carboxylic Acid (Celebrex Carboxylic Acid, 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic Acid) | A metabolite of Celebrex, a Cox-2 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 170571-01-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Celecoxib Carboxylic Acid Methyl Ester | Intermediate for the preparation of Celebrex Carboxylic Acid. Group: Biochemicals. Alternative Names: 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic Acid Methyl Ester; Celebrex Carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1189893-75-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Celecoxib (Celebrex, 4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide) | Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits prostaglandin production. Celecoxib is approximately 7.6-fold more selective for COX-2 inhibition over COX-1. This specificity allows celecoxib to reduce inflammation and pain while minimizing gastrointestinal adverse drug reactions (e.g. stomach ulcers) that are common with non-selective non-steroidal anti-inflammatory drugs (NSAIDs). Group: Biochemicals. Alternative Names: Celecoxib, 4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 169590-42-5. Pack Sizes: 300mg, 500mg, 1g, 5g. Molecular Formula: C17H14F3N3O2S, Molecular Weight: 381.37. US Biological Life Sciences. | Worldwide |
| Celecoxib-d4 (4-[5-(4-Methylphenyl) -3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide-d4, Celebrex-d4) | A deuterated Cox-2 inhibitor. Group: Biochemicals. Alternative Names: Celecoxib-d4 (4-[5-(4-Methylphenyl) -3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide-d4, Celebrex-d4). Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Celecoxib Impurity 1 | Celecoxib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-(m-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide. CAS No. 170570-01-1. Molecular formula: C17H14F3N3O2S. Mole weight: 381.37. Catalog: APB170570011. |  |
| Celecoxib Impurity 12 | Celecoxib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122-00-9. Molecular formula: C9H10O. Mole weight: 134.18. Catalog: APB122009. | |
| Celecoxib Impurity 14 | Celecoxib Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-4-((1,1,1-trifluoro-4-oxo-4-(p-tolyl)butan-2-ylidene)amino)benzenesulfonamide. CAS No. 1061214-09-2. Molecular formula: C17H15F3N2O3S. Mole weight: 384.37. Catalog: APB1061214092. | |
| Celecoxib Impurity 2 | An impurity of celecoxib, a cyclooxygenase 2 inhibitor. Synonyms: 1H-Pyrazole, 5-(4-methylphenyl)?-3-(trifluoromethyl)?-; 5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(4-Methylphenyl)-3-trifluoromethyl-1H-pyrazole; Celecoxib Impurity H. Grades: > 95%. CAS No. 948293-46-7. Molecular formula: C11H9F3N2. Mole weight: 226.2. | |
| Celecoxib Impurity 2 | Celecoxib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-(o-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide. CAS No. 170569-99-0. Molecular formula: C17H14F3N3O2S. Mole weight: 381.37. Catalog: APB170569990. | |
| Celecoxib Impurity 3 | Celecoxib Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-(2,4-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide. CAS No. 170570-09-9. Molecular formula: C18H16F3N3O2S. Mole weight: 395.4. Catalog: APB170570099. | |
| Celecoxib Impurity 4 | Celecoxib Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide. CAS No. 170569-87-6. Molecular formula: C16H12F3N3O2S. Mole weight: 367.35. Catalog: APB170569876. | |
| Celecoxib Impurity 5 | A metabolite of Celecoxib. Synonyms: 4-[5-[4-(Hydroxymethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. Grades: > 95%. CAS No. 170571-00-3. Molecular formula: C17H14F3N3O3S. Mole weight: 397.38. | |
| Celecoxib Impurity 54 | Celecoxib Impurity 54. Uses: For analytical and research use. Group: Impurity standards. CAS No. 170570-75-9. Molecular formula: C17H13BrF3N3O2S. Mole weight: 460.27. Catalog: APB170570759. | |
| Celecoxib Impurity 7 | Celecoxib Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-4-(2-(1-(p-tolyl)ethylidene)hydrazinyl)benzenesulfonamide. CAS No. 1061214-06-9. Molecular formula: C15H17N3O2S. Mole weight: 303.38. Catalog: APB1061214069. | |
| Celecoxib Impurity A | Cas No. 170570-01-1. | |
| Celecoxib Impurity C | Cas No. 170569-99-0. | |
| Celecoxib Impurity E | Celecoxib Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1674390-41-0. Molecular formula: C15H20ClN3O3S. Mole weight: 357.85. Catalog: APB1674390410. | |
| Celecoxib Impurity HCl (4-Hydrazinobenzene-1-sulfonamide HCl) | 4-Sulfonamide-Phenylhydrazine HCl is an intermediate to produce Celebrex. Synonyms: 4-Hydrazino-benzenesulfonamide Hydrochloride; [4-(Aminosulfonyl)phenyl]hydrazine Hydrochloride. Grades: > 95%. CAS No. 17852-52-7. Molecular formula: C6H9N3O2S.HCl. Mole weight: 223.68. | |
| Celecoxib Impurity M | Celecoxib Impurity M. Uses: For analytical and research use. Group: Impurity standards. CAS No. 170571-00-3. Molecular formula: C17H14F3N3O3S. Mole weight: 397.37. Catalog: APB170571003. | |
| Celecoxib impurity (N-Acetyl-4-(2-Aminoethyl)-Benzenesulfonamide) | N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-acetamide is used in the synthesis of sulfonylurea and thiourea derivatives substituted with benzenesulfonamide groups that can be used as potential hypoglycemic agents. Synonyms: N-p-Sulfamoylphenethyl-acetamide; 4-(2-Acetylaminoethyl)benzenesulfonamide; N-(p-Sulfamoylphenethyl)acetamide. Grades: > 95%. CAS No. 41472-49-5. Molecular formula: C10H14N2O3S. Mole weight: 242.3. | |
| Celecoxib-NBD | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Celecoxib Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Celecoxib Related Compound B | Cas No. 331943-04-5. | |
| Celecoxib Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Celecoxib Related Compound D | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| 2,5-Dimethylcelecoxib | 2,5-Dimethylcelecoxib is an analogue of celecoxib (HY-14398) with anticancer activity but without COX-2 inhibitory activity. 2,5-Dimethylcelecoxib exerts its anti-cancer cell proliferation effect by inhibiting the core mechanism of the Wnt/β-catenin signaling pathway. 2,5-Dimethylcelecoxib also inhibits T-cell factor-dependent transcriptional activity and inhibits expression of the Wnt/β-catenin target gene products cyclin D1 and survivin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 457639-26-8. Pack Sizes: 1 mg. Product ID: HY-W010995. | |
| 2,5-Dimethyl-celecoxib | 2,5-dimethyl Celecoxib is a celecoxib derivative and a targeted inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), a key enzyme in the PGE2 synthesis pathway of inflammatory mediators. Synonyms: 2,5-Dimethyl Celecoxib; 4-[5-(2,5-Dimethylphenyl)-3-trifluormethyl-1H-pyrazole-1-yl]benzensulfonamide; DMC; 2,5-Dimethylcelecoxib; Celecoxib Impurity 42; Celecoxib Impurity K. Grades: ≥95%. CAS No. 457639-26-8. Molecular formula: C18H16F3N3O2S. Mole weight: 395.40. | |
| 2,5-Dimethyl-celecoxib | 2,5-Dimethyl-celecoxib. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,5-dimethylcelecoxib, 457639-26-8, 2,5-dimethyl-celecoxib, Dimethyl Celecoxib, AGN-PC-00BARL, SureCN2228663, CHEMBL2163630, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide, 4-(5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide\r\n, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide. Appearance: solid. CAS No. 457639-26-8. Molecular formula: C18H16F3N3O2S. Mole weight: 395.4. Purity: 98%+. IUPACName: 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. Canonical SMILES: CC1=CC(=C(C=C1)C)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F. Product ID: ACM457639268. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2,5-Dimethyl Celecoxib | A non-cyclooxygenase-2 inhibitor analog of Celecoxib. The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib. Group: Biochemicals. Alternative Names: 4-[5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; DMC. Grades: Highly Purified. CAS No. 457639-26-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 2-Methyl-Celecoxib | 2-Methyl-Celecoxib is an analog of the anti-inflammatory drug Celecoxib (C251000). Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 170570-09-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H16F3N3O2S, Molecular Weight: 395.4. US Biological Life Sciences. | Worldwide |
| 2-Methyl-Celecoxib | An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Synonyms: 4-[5-(2,4-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. Grades: >95%. CAS No. 170570-09-9. Molecular formula: C18H16F3N3O2S. Mole weight: 395.41. | |
| 4-Desmethyl-3-methyl Celecoxib | A meta positional isomer of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Biochemicals. Alternative Names: 4-[5-(3-Methylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 170570-01-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Carboxylic acid celecoxib | Celecoxib Carboxylic Acid is a metabolite of Celecoxib, a Cox-2 inhibitor. Synonyms: 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic Acid; Celebrex Carboxylic Acid. Grades: > 95%. CAS No. 170571-01-4. Molecular formula: C17H12F3N3O4S. Mole weight: 411.36. | |
| Dehydroxy Bromocelecoxib | Dehydroxy Bromocelecoxib is an intermediate in the synthesis of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor with known anti-inflammatory properties. Group: Biochemicals. Alternative Names: 4-[5-[4-(Bromomethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide. Grades: Highly Purified. CAS No. 170570-75-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Desmethyl Celecoxib | An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Synonyms: 4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. Grades: >95%. CAS No. 170569-87-6. Molecular formula: C16H12F3N3O2S. Mole weight: 367.346. | |
| Hydroxy celecoxib | Hydroxy celecoxib. Group: Biochemicals. Alternative Names: 4-[5-[4-(Hydroxymethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 170571-00-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H14F3N3O3S. US Biological Life Sciences. | Worldwide |
| N-De(4-sulfonamidophenyl)-N'-(4-sulfonamidophenyl) celecoxib | N-De(4-sulfonamidophenyl)-N'-(4-sulfonamidophenyl) celecoxib. Group: Biochemicals. Alternative Names: 4-[3-(4-Methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 331943-04-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H14F3N3O2S. US Biological Life Sciences. | Worldwide |
| N-De(4-sulfonamidophenyl)-N-(4-sulfonamidophenyl) Celecoxib | An isomeric impurity of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Biochemicals. Alternative Names: 4-[3-(4-Methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 331943-04-5. Pack Sizes: 10mg, 20mg, 50mg. US Biological Life Sciences. | Worldwide |
| 1,1,1-Trifluoro-4-methoxy-4-(4-methylphenyl)-3-buten-2-one | Intermediate in the preparation of a Celecoxib impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 187812-31-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1-(4-Methylphenyl)-4,4,4-trifluorobutane-1,3-dione | A Celecoxib (Celebrex) intermediate. Group: Biochemicals. Alternative Names: 4,4,4-Trifluoro-1-(4-methylphenyl)-. Grades: Highly Purified. CAS No. 720-94-5. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 1-Carboxy-1-methylethoxyammonium Hydrochloride | 1-Carboxy-1-methylethoxyammonium Hydrochloride is used as a reactant in the synthesis of carbon-11 labeled celecoxib derivatives as new candidate PET radioligands for imaging of inflammation. Group: Biochemicals. Grades: Highly Purified. CAS No. 89766-91-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C4H9NO3 HCl. US Biological Life Sciences. | Worldwide |
| 2-Acetylphenanthrene | 2-Acetylphenanthrene acts as a reagent in the synthetic preparation of anti-staphylococcal Celecoxib (C251000) derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 5960-69-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C16H12O. US Biological Life Sciences. | Worldwide |
| 3-(4-Methylphenyl)-5-(trifluoromethyl)-1H-pyrazole | An impurity of Celecoxib, a cyclooxygenase 2 inhibitor. Synonyms: 3-(4-methylphenyl)-5-(trifluoromethyl)pyrazole; 3-(Trifluoromethyl)-5-p-tolyl-1H-pyrazole; 3-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole. Grades: 95 %. CAS No. 219986-64-8. Molecular formula: C11H9F3N2. Mole weight: 226.2. | |
| 4- (2- (2, 2, 2-trifluoroacetyl) hydrazinyl) benzenesulfonamide | An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Synonyms: 4- (2- (2, 2, 2-trifluoroacetyl) hydrazinyl) benzenesulfonamide; 4-[2- (1-Hydroxy-2, 2, 2-trifluoroethylidene) hydrazino]benzenesulfonamide; 4-[2- (2, 2, 2-trifluoroacetyl) hydrazinyl]benzenesulfonamide; Celecoxib Hydrazine; F77670; 4-(2,2,2-trifluoroacetohydrazido)benzene-1-sulfonamide; B0070-284948. CAS No. 915280-81-8. Molecular formula: C8H8F3N3O3S. Mole weight: 283.23. | |
| 4, 4, 4-Trifluoro-2- (aminomethylphenyl) methylene-3-oxo-butanoic Acid Ethyl Ester | Intermediate in the preparation of a Celecoxib impurity. Group: Biochemicals. Alternative Names: 2-[Amino- (4-methylphenyl) ]methylene-4, 4, 4-trifluoro-3-oxo-butanoic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Angiogenesis related Compound Library | A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries. |  |
| COX-2-IN-18 | COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity ( IC 50 = 0.775 μM) compared to the reference agent, Celecoxib ( IC 50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1038061-96-9. Pack Sizes: 5 mg. Product ID: HY-147794. | |
| MK-886 | This active molecular is a leukotriene antagonist with the IC50 of 3 nM in human polymorphonuclear leukocytes. MK-886 also inhibits PPARα activation. Inhibition of 5-lipoxygenase-activating protein (FLAP) leads to inhibited 5-lipoxygenase (5-LOX), and this may help in treating atherosclerosis. MK-886 and Celecoxib have an inhibitory effect on the growth of pancreatic cancer cell line SW1990 and angiogenesis. In Mar 1996, an animal study had been added to the Ischaemic Heart Disease pharmacodynamics section. Uses: Ischaemic heart disease. Synonyms: MK-886; MK886; MK 886; L-663,536; L663,536; L 663,536; L-663536; L663536; L 663536; 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid,L-663,536,118427-55-7( MK-886 Sodium Salt). Grades: 98%. CAS No. 118414-82-7. Molecular formula: C27H34ClNO2S. Mole weight: 472.08. | |
| S-Adenosyl-L-Methionine | S-adenosyl-l-methionine (SAMe) is a naturally occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior to that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side effects, it is a potentially important treatment for depression. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee. It also acts as a PDE4B inhibitor. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Ademetionine; AdoMet; MSI-195; MSI 195; MSI195; SAMe; S-adenosylmethionine. Heptral; Gumbaral. S-Adenosyl-L-methionine; S-Adenosyl methionine; SAMe; AdoMet; (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate. Grades: 98%. CAS No. 29908-03-0. Molecular formula: C15H22N6O5S. Mole weight: 398.438. | |
| Sitagliptin Impurity 26 | Sitagliptin Impurity 26 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Celecoxib Trifluro Impurity; 1-(4-Methylphenyl)-3-hydroxy-4,4,4-trifluoro-2-butene-1-one. Grades: > 95%. CAS No. 910303-54-7. Molecular formula: C11H9F3O2. Mole weight: 230.18. | |
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