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Some chitinases also display the activity defined in EC 3.2.1.17 lysozyme. Group: Enzymes. Synonyms: chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase. Enzyme Commission Number: EC 3.2.1.14. CAS No. 9001-6-3. Chitinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3822; chitinase; EC 3.2.1.14; 9001-06-3; chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase. Cat No: EXWM-3822.
CHITINASE
HGAPDH is an antifungal peptide isolated from Streptomyces violaceus. Synonyms: Glu-Gln-Pro-Gly-Gly-Asp-Lys-Val-Asn-Leu-Gly-Tyr-Phe-Thr-Asn. Grades: 96.9%. CAS No. 9001-6-3. Molecular formula: C72H107N19O25. Mole weight: 1638.75.
Chitinase 18A from Bacillus cereus, Recombinant
Chitosanase catalyzes the endohydrolysis of β (1,4) linkages between N-acetyl-D-glucosamine and D-glucosamine residues in partially deacetylated chitosan. Chitosanase from Streptomyces griseus is capable of hydrolyzing both chitosan and carboxymethyl cellulose. It is used for the lysis of cell walls of fungi belonging to the group Mucorales. It is found in several types of microorganisms. Group: Enzymes. Synonyms: Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase. Enzyme Commission Number: EC 3.2.1.14. Purity: >90% by SDS-PAGE. Chitosanase. Mole weight: 38.3 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacillus cereus. Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase; Chitosanase 18A. Cat No: NATE-1377.
Chitinase 18A from Bacillus licheniformis, Recombinant
Chitosanase catalyzes the endohydrolysis of β (1,4) linkages between N-acetyl-D-glucosamine and D-glucosamine residues in partially deacetylated chitosan. Chitosanase from Streptomyces griseus is capable of hydrolyzing both chitosan and carboxymethyl cellulose. It is used for the lysis of cell walls of fungi belonging to the group Mucorales. It is found in several types of microorganisms. Group: Enzymes. Synonyms: Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase. Enzyme Commission Number: EC 3.2.1.14. Purity: >90% by SDS-PAGE. Chitosanase. Mole weight: 49.2 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacillus licheniformis. Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase; Chitosanase 18A. Cat No: NATE-1378.
Chitinase 18A from Clostridium thermocellum, Recombinant
Chitosanase catalyzes the endohydrolysis of β (1,4) linkages between N-acetyl-D-glucosamine and D-glucosamine residues in partially deacetylated chitosan. Chitosanase from Streptomyces griseus is capable of hydrolyzing both chitosan and carboxymethyl cellulose. It is used for the lysis of cell walls of fungi belonging to the group Mucorales. It is found in several types of microorganisms. Group: Enzymes. Synonyms: Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase. Enzyme Commission Number: EC 3.2.1.14. Purity: >90% by SDS-PAGE. Chitosanase. Mole weight: 43.9 kDa. Activity: 25 U/mg. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Clostridium thermocellum. Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase; Chitosanase 18A. Cat No: NATE-1379.
Chitinase from Aspergillus niger (food grade)
Chitinase is an extracellular enzyme complex that degrades chitin. Chitin is degraded to N-acetyl-D-glucosamine in 2 enzymatic reactions. Group: Enzymes. Synonyms: Chitinase; chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Enzyme Commission Number: EC 3.2.1.14. CAS No. 9001-6-3. Chitinase. Activity: 200U/g min. Stability: 1 year when properly stored. Storage: STORED HUMIDITY PROTECTED (RH LESS THAN 60) AT TEMPERATURE BELOW 25°C. Form: Light-brown Powder. Source: Aspergillus niger. Chitinase; chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Cat No: DIS-1010.
Chitinase from Clostridium thermocellum, Recombinant
Chitinase is an extracellular enzyme complex that degrades chitin and has a molecular mass of approximately 30 kDa. Chitin is degraded to N-acetyl-D-glucosamine in 2 enzymatic reactions. Firstly, chitobiose units are removed from chitin by chitodextrinase-chitinase. The second reaction involves N-acetyl-glucosaminidase-chitobiase, which cleaves the disaccharide to its monomer subunits (that comprise of N-acetyl-D-glucosamine). Group: Enzymes. Synonyms: Chitinase; chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Enzyme Commission Number: EC 3.2.1.14. Purity: > 80 % as judged by SDS-PAGE. Chitinase. Mole weight: 43927.1 Da. Activity: 25 U/mg. Storage: Store at -20°C (shipped at room temperature). Form: Glycerol/buffer solution. Source: Clostridium thermocellum ATCC 27405. Chitinase; chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Cat No: NATE-1201.
Chitinase-IN-1
Chitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 75%/67% for chitinase/N- acetyl-hexosaminidase respectively. Synonyms: Chitinase-IN-1. Grades: >98%. CAS No. 1579991-61-9. Molecular formula: C18H16N4O2S. Mole weight: 352.41.
Chitinase-IN-2
Chitinase-IN-2 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 98%/92% for chitinase/N- acetyl-hexosaminidase respectively. Synonyms: Chitinase-IN-2. Grades: >98%. CAS No. 1579991-63-1. Molecular formula: C20H21N5O2S. Mole weight: 395.48.
Chitinase, Serratia marcescens
Chitinase, Serratia marcescens (EC 3.2.1.14) has partial lysozyme activity and is widely found in bacteria, fungi, animals and some plants. Chitinase belongs to the glycosyl hydrolase family. Chitinase catalyzes chito-oligosaccharide hydrolysis. Chitinases also can serve as prognostic biomarkers of disease progression. Chitinase can be used in the research of pathogenesis of various human fibrotic and inflammatory disorders, particularly those of the lung (idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, sarcoidosis, and asthma) and the gastrointestinal tract (inflammatory bowel diseases (IBDs) and colon cancer) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMCase, Serratia marcescens. CAS No. 9001-6-3. Pack Sizes: 5 U. Product ID: HY-P2797.
Chitinase, Streptomyces griseus
Chitinase, Streptomyces griseus is a chitinase mainly found in Bacillus species and uses colloidal chitin as a substrate. The Km and Vmax of Chitinase are 4.28 mg/mL and 14.29 μg/(Min·mL) respectively. The final enzymatic hydrolysis product is N-acetylglucosamine, and the monomer and dimer contents are 14.33% and 85.67% respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMCase, Streptomyces griseus. CAS No. 9001-6-3. Pack Sizes: 1 g; 5 g. Product ID: HY-P2797A.
Acidic Mammalian Chitinase Inhibitor, Bisdionin F
A cell-permeable, competitive Acidic Mammalian Chitinase (AMCase) Inhibitor (IC50=0.92uM and Ki=0.42uM for hAMCase, and IC50=2.2uM for mAMCase, in vitro) that demonstrates 20-fold selectivity for hAMCase over hCHIT1. It is shown to decrease chitinase enzymatic activity (5mg/kg, i.p.) in the lungs of control PBS- and OVA-challenged mice. Furthermore, it attenuates lung chitinase activity, reduces eosinophil influx, and improves ventilatory function, in vivo, in a murine model of allergic inflammation. It also causes neutrophilia in the lungs of OVA-challenged mice. Group: Biochemicals. Alternative Names: AMCase Inhibitor, 3,7-dimethyl-1-(3-(3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)propyl)-1H-purine-2,6(3H,7H)-dione. Grades: Highly Purified. CAS No. 917877-86-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Native Streptomyces griseus Chitinase
Chitinase is an extracellular enzyme complex that degrades chitin and has a molecular mass of approximately 30 kDa. Chitin is degraded to N-acetyl-D-glucosamine in 2 enzymatic reactions. Firstly, chitobiose units are removed from chitin by chitodextrinase-chitinase. The second reaction involves N-acetyl-glucosaminidase-chitobiase, which cleaves the disaccharide to its monomer subunits (that comprise of N-acetyl-D-glucosamine). Applications: Chitinase from streptomyces griseus has been used to study the effect of the allosamidin on the regulatory system for chitinase production. it has also been used to study the enrichment of chitinolytic microorganisms. this enrichment wa...;-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Enzyme Commission Number: EC 3.2.1.14. CAS No. 9001-6-3. Chitinase. Activity: > 200 units/g solid. Storage: -20°C. Form: lyophilized powder (essentially salt free). Source: Streptomyces griseus. Chitinase; chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Cat No: NATE-0123.
Native Trichoderma viride Chitinase
Chitinase is an extracellular enzyme complex that degrades chitin and has a molecular mass of approximately 30 kDa. Chitin is degraded to N-acetyl-D-glucosamine in 2 enzymatic reactions. Firstly, chitobiose units are removed from chitin by chitodextrinase-chitinase. The second reaction involves N-acetyl-glucosaminidase-chitobiase, which cleaves the disaccharide to its monomer subunits (that comprise of N-acetyl-D-glucosamine). Applications: Chitinase from trichoderma viride has been used in a study to investigate the differential release of high mannose structural isoforms by fungal and bacterial endo-β-n-acetylglucosaminidases. chitinase from trichoderma viride has al...glucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Enzyme Commission Number: EC 3.2.1.14. CAS No. 9001-6-3. Chitinase. Activity: > 600 units/g solid. Storage: -20°C. Form: lyophilized powder. Source: Trichoderma viride. Chitinase; chitodextrinase; 1,4-β-poly-N-acetylglucosaminidase; poly-β-glucosaminidase; β-1,4-poly-N-acetyl glucosamidinase; poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase; (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase; EC 3.2.1.14. Cat No: NATE-0124.
2-Iodopropane-d7
2-Iodopropane-d7 is the isotope labelled analog of 2-Iodopropane (I718795); a reagent used in the synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates. Group: Biochemicals. Grades: Highly Purified. CAS No. 101927-33-7. Pack Sizes: 10mg, 100 mg. Molecular Formula: C3D7I, Molecular Weight: 177. US Biological Life Sciences.
Worldwide
2-Iodopropane (Stabilized with Copper)
2-Iodopropane is used as a reagent in the synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates. Group: Biochemicals. Grades: Highly Purified. CAS No. 75-30-9. Pack Sizes: 1g, 10g. Molecular Formula: C3H7I. US Biological Life Sciences.
4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-glucopyranoside, a fluorogenic substrate, is primarily employed in assay development for chitinases and other glycosidases. Its utility lies in its ability to discern the substrate specificities of chitinases, alongside affording a quantitative measurement of chitinase activity. Synonyms: 4-Methylumbelliferyl N-acetyl-a-D-glucosaminide 4MU-a-GlcNAc. CAS No. 80265-04-9. Molecular formula: C18H21NO8. Mole weight: 379.36.
4-Methylumbelliferyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-galactopyranoside, a vital compound utilized in biomedical research, exhibits immense intricacy. Its fluorigenic substrate properties make it indispensable in studying chitinase activity, especially in relation to carbohydrate metabolism enzymes. This exceptional compound finds extensive utility in assays dedicated to comprehending the pathogenesis of diverse ailments, comprising fungal infections and inflammatory disorders. Synonyms: 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-beta-D-Galactopyranoside; 4-Methylumbelliferyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-galactopyranoside; [(2R,3R,4R,5R,6S)-5-acetamido-3,4-diacetyloxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl acetate; (2R,3R,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate; W-200973; 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-?-D-Galactopyranoside; [(2R,3R,4R,5R,6S)-3,4-bis(acetyloxy)-5-acetamido-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]oxan-2-yl]methyl acetate. CAS No. 124167-46-0. Molecular formula: C24H27NO11. Mole weight: 505.47.
4-Methylumbelliferyl 4-Deoxy-β-D-chitobiose Peracetate is a highly noteworthy substance, serving as an indispensable instrument for studying the intricacies surrounding chitinase function. With its remarkable precision and sensitivity, this compound impeccably facilitates the identification and analysis of chitinase activity. Synonyms: 4-Methylumbelliferyl 4-Deoxy-|A-D-chitobiose Peracetate; 4-Methylumbelliferyl 4-Deoxy-beta-D-chitobiose Peracetate; [(2S,4S,5R,6S)-5-acetamido-6-[(2R,3S,4R,5R,6S)-5-acetamido-4-acetyloxy-2-(acetyloxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]oxy-4-acetyloxyoxan-2-yl]methyl acetate; 4-Methylumbelliferyl 4-Deoxy-b-D-chitobiose Peracetate; DTXSID50673187; 4-Methyl-2-oxo-2H-1-benzopyran-7-yl 2-acetamido-4-O-(2-acetamido-3,6-di-O-acetyl-2,4-dideoxy-beta-D-xylo-hexopyranosyl)-3,6-di-O-acetyl-2-deoxy-beta-D-glucopyranoside. CAS No. 1228931-52-9. Molecular formula: C34H42N2O15. Mole weight: 718.70.
4-Methylumbelliferyl 4-deoxychitobiose
4-Methylumbelliferyl 4-deoxychitobiose is an incredibly valuable compound, specifically focusing on the intricate study of carbohydrates and enzyme conduct. As a fluorogenic substrate, it serves as a key facet in the appraisal of chitinases and their enzymatic behaviors. Synonyms: 4-Methylumbelliferyl 4-deoxychitobiose; 618446-98-3; 4-Methylumbelliferyl 4-Deoxy-?-D-chitobiose. CAS No. 618446-98-3. Molecular formula: C26H34N2O12. Mole weight: 566.55.
4-Methylumbelliferyl a-D-glucosaminide
4-Methylumbelliferyl α-D-glucosaminide is a valuable tool in research for detecting chitinase activity. This substrate can be hydrolyzed by chitinases, enzymes involved in various diseases such as asthma is arthritis is and gastrointestinal disorders. Its fluorescent properties allow for easy detection and quantification, making it ideal for studying chitinase-related diseases and developing potential researchs. Synonyms: 4-Methylumbelliferyl 2-amino-2-deoxy-a-D-glucopyranoside. CAS No. 137687-00-4. Molecular formula: C16H19NO7. Mole weight: 337.32.
4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is a fluorogenic substrate for chitinases and chitotriosidases. It is cleaved by chitinases and chitotriosidases to release the fluorescent moiety 4-methylumbelliferyl (4-MU). Synonyms: 7-[[O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1?4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1?4)-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one; MUF-triNAG. Grades: ≥98%. CAS No. 53643-13-3. Molecular formula: C34H47N3O18. Mole weight: 785.8.
4-Methylumbelliferyl N,N-diacetyl-b-D-chitobioside, a remarkable biomedicine offering, thrives within the realm of the biomedical industry. Its paramount function revolves around serving as an impeccable substrate for detecting, as well as quantifying chitinase activity. This extraordinary compound devoutly aids researchers in delving into the intricacies of chitinase enzymes, thereby unraveling their involvement in multifarious biological processes. Synonyms: N,N-Diacetyl-4-methylumbelliferyl-b-D-chitobioside. CAS No. 53643-12-2. Molecular formula: C26H34N2O13. Mole weight: 582.55.
4-Methylumbelliferyl N,N,N,N-tetraacetyl-b-D-chitotetraoside is a vital compound extensively used in biomedicine. This product plays a crucial role in the study of chitinase enzymes and their involvement in various diseases. Synonyms: GlcNAc1-b-4GlcNAc1-b-4GlcNAc1-b-4GlcNAc1-b-4MU. CAS No. 53643-14-4. Molecular formula: C42H60N4O23. Mole weight: 988.94.
4-Nitrophenyl N,N,N-triacetyl-b-D-chitotriose
4-Nitrophenyl N,N,N-triacetyl-b-D-chitotriose is a biomedical compound of significant interest, offering immense potential in the research of diverse diseases. Remarkably, it exhibiting remarkable anti-inflammatory properties, rendering it an invaluable resource for drug development specifically targeting inflammatory ailments, including arthritis and asthma. Synonyms: 4-Nitrophenyl beta-D-N,N',N''-triacetylchitotriose; N-[2-[5-acetamido-6-[5-acetamido-4-hydroxy-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide;4-Nitrophenyl beta-D-N,N',N''-triacetylchitotriose, chitinase and lysozyme substrate; 4-Nitrophenyl 2-acetamido-2-deoxyhexopyranosyl-(1->4)-2-acetamido-2-deoxyhexopyranosyl-(1->4)-2-acetamido-2-deoxyhexopyranoside. CAS No. 7699-38-9. Molecular formula: C30H44N4O18. Mole weight: 748.69.
5-(Biotinamido)-pentylamine
Biotincadaverine. Chitinase substrate for colorimetric assay. CAS No. 115416-38-1. Product ID: 9-00906. Molecular formula: C15H28N4O2S. Mole weight: 328.5. Properties:
Allosamidin
It is produced by the strain of Streptomyces sp. Chitinase specific inhibitor. Synonyms: A82516; A-82516; beta-D-Allopyranoside, 2-(dimethylamino)-3a,5,6,6a-tetrahydro-4-hydroxy-6-(hydroxymethyl)-4H-cyclopentoxazol-5-yl 2-(acetylamino)-4-O-(2-(acetylamino)-2-deoxy-beta-D-allopyranosyl)-2-deoxy-, (3aalpha,4beta,5beta,6alpha,6aalpha)-; Allosamidine; A 82516; 1,2-Dideoxy-2'-dimethylamino-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline; CHEMBL118668; DTXSID90883122; BDBM50331851; ZINC53683592; DB04628; LS-171885; C05346; W-200706; Q27095365; (3aR,4R,5R,6S,6aS)-2-(dimethylamino)-4-hydroxy-6-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-yl 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-allopyranosyl]-2-deoxy-beta-D-allopyranoside. Grades: 99%. CAS No. 103782-08-7. Molecular formula: C25H42N4O14. Mole weight: 622.62.
Argifin
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively. CAS No. 243975-37-3. Molecular formula: C29H41N9O10. Mole weight: 675.69.
Benzyl 2,2,2-trichloroacetimidate
Benzyl 2,2,2-Trichloroacetimidate is a reactant used in the synthesis of Allosamidin; an insect chitinase inhibitor. Synonyms: 2,2,2-Trichloroethanimidic Acid Phenylmethyl Ester; 2,2,2-Trichloroacetimidic Acid Benzyl Ester; Benzyl Trichloroacetimidate; O-Benzyl 2,2,2-Trichloroacetimidate; Benzyltrichloroacetimidate; Trichloroacetimidic Acid Benzyl Ester; Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester. Grades: > 98 %. CAS No. 81927-55-1. Molecular formula: C9H8Cl3NO. Mole weight: 252.52.
Benzyl 2,2,2-Trichloroacetimidate
Benzyl 2,2,2-Trichloroacetimidate is a reactant used in the synthesis of Allosamidin (A547900); an insect chitinase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 81927-55-1. Pack Sizes: 10g, 25g. Molecular Formula: C9H8Cl3NO. US Biological Life Sciences.
Worldwide
CHI3L1-IN-1
CHI3L1-IN-1 (Compound 30) is an inhibitor for Chitinase-3-like protein 1 ( CHI3L1 ) (YKL-40) with IC 50 of 50 nM. CHI3L1-IN-1 inhibits hERG channel with an IC 50 of 2.3 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2982256-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163387.
Chitin azure
Chitin azure has been used as a substrate to determine chitinase activity.
chitin disaccharide deacetylase
Chitin oligosaccharide deacetylase is a key enzyme in the chitin catabolic cascade of chitinolytic Vibrio strains. Besides being a nutrient, the heterodisaccharide product 4-O-(N-acetyl-β-D-glucosaminyl)-D-glucosamine is a unique inducer of chitinase production in Vibrio parahemolyticus. In contrast to EC 3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide. It also deacetylates the chitin trisaccharide with lower efficiency. No activity with higher polymers of GlcNAc. Group: Enzymes. Synonyms: chitobiose amidohydolase; COD; chitin oligosaccharide deacetylase; chitin oligosaccharide amidohydolase; 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-deoxy-D-glucopyranose acetylhydrolase. Enzyme Commission Number: EC 3.5.1.105. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4384; chitin disaccharide deacetylase; EC 3.5.1.105; chitobiose amidohydolase; COD; chitin oligosaccharide deacetylase; chitin oligosaccharide amidohydolase; 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-deoxy-D-glucopyranose acetylhydrolase. Cat No: EXWM-4384.
Chitotriose undecaacetate
Chitotriose undecaacetate, a biomedically renowned compound, emerges as a multifaceted therapeutic agent. Its remarkable attributes encompass potent antimicrobial effects, rendering it an ideal intervention against both bacterial and fungal infections. Moreover, its inhibitory properties as a chitinase inhibitor have unveiled promising prospects in the realm of innovative drug discovery, specifically targeting afflictions associated with chitin-induced ailments. Synonyms: Tri-N-acetyl-chitotriose octaacetate; O-3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1-4)-O-3,6-di-O-acetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-1,3,6-triacetate-α-D-glucopyranose; 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-2-acetamido-3,6-di-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-2-acetamido-1,3,6-tri-O-acetyl-2-deoxy-D-glucopyranose. Grades: ≥95%. CAS No. 53942-45-3. Molecular formula: C40H57N3O24. Mole weight: 963.89.
Closantel
Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase ( OvCHT1 ) inhibitor with an IC 50 of 1.6 μM and a K i of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57808-65-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17596.
Closantel sodium
Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase ( OvCHT1 ) inhibitor with an IC 50 of 1.6 μM and a K i of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61438-64-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-17596A.
Dibenzylideneacetone (Dibenzalacetone) is a potent inhibitor of chitinase with an IC 50 value of 13.10 μM. The MIC value of Dibenzylideneacetone against Botrytis cinerea is 32 μg/mL, and the EC 50 values for inhibiting mycelium growth and spore germination are 16.29 and 14.64 μg/mL, respectively. Dibenzylideneacetone can be used in research on fruit and vegetable preservatives [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dibenzalacetone. CAS No. 538-58-9. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-75828.
Glucoallosamidin A
Glucoallosamidin A is a glycoside antibiotic produced by the strain of Streptomyces sp. SA-684. It can inhibit Chitinase activity. Grades: 95%. CAS No. 136236-41-4. Molecular formula: C26H44N4O14. Mole weight: 636.64.
Glucoallosamidin B
Glucoallosamidin B is a glycoside antibiotic produced by the strain of Streptomyces sp. SA-684. It can inhibit Chitinase activity. Synonyms: beta-D-Glucopyranoside,3A,5,6,6A-tetrahydro-4-hydroxy-6-(hydroxymethyl)-2-(methylamino)-4H-cyclopentoxazol-5-yl 2-(acetylamino)-4-o-(2-(acetylamino)-2-deoxy-6-o-methyl-beta-D-allopyranosyl)-2-deoxy-, (3ar-(3aalpha, 4alpha, 5beta, 6alpha, 6aalpha))-. Grades: 95%. CAS No. 136236-42-5. Molecular formula: C25H42N4O14. Mole weight: 622.62.
lysozyme
cf. also EC 3.2.1.14 chitinase. Group: Enzymes. Synonyms: muramidase; globulin G; mucopeptide glucohydrolase; globulin G1; N,O-diacetylmuramidase; lysozyme g; L-7001; 1,4-N-acetylmuramidase; mucopeptide N-acetylmuramoylhydrolase; PR1-lysozyme. Enzyme Commission Number: EC 3.2.1.17. CAS No. 9001-63-2. Lysozyme. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3852; lysozyme; EC 3.2.1.17; 9001-63-2; muramidase; globulin G; mucopeptide glucohydrolase; globulin G1; N,O-diacetylmuramidase; lysozyme g; L-7001; 1,4-N-acetylmuramidase; mucopeptide N-acetylmuramoylhydrolase; PR1-lysozyme. Cat No: EXWM-3852.
Native Arthrobacter luteus Lyticase
Lyticase hydrolyzes poly-β (1?3)-glucose such as yeast cell wall glucan. Applications: Yeast cells are difficult to disrupt because the cell walls may form capsules or resistant spores. dna can be extracted from yeast by using lysing enzymes such as lyticase, chitinase, zymolase, and gluculase to induce partial spheroplast formation; spheroplasts are subsequently lysed to release dna. lyticase is preferred to digest cell walls of yeast and generate spheroplasts from fungi for transformation. reported to be useful for lysis of ashbya, candida, debaryomyces, eremothecium, endomyces, hansenula, hanseniaspora, kloeckera, kluyveromyces, lipomyces, metschikowia, pichia, pullularia, torulopsis, saccharomyces, saccharomycopsis, saccharomycodes, and schwanniomyces species. Group: Enzymes. Synonyms: Lyticase; 37340-57-1. CAS No. 37340-57-1. Lyticase. Activity: > 200 units/mg solid; > 1,500 units/mg protein; > 2,000 units/mg protein, Protein > 20 % by biuret. Storage: 2-8°C. Form: lyophilized powder. Source: Arthrobacter luteus. Lyticase; 37340-57-1. Cat No: NATE-0431.
Native Streptomyces griseus Chitosanase
Chitosanase catalyzes the endohydrolysis of β (1,4) linkages between N-acetyl-D-glucosamine and D-glucosamine residues in partially deacetylated chitosan. Chitosanase from Streptomyces griseus is capable of hydrolyzing both chitosan and carboxymethyl cellulose. It is used for the lysis of cell walls of fungi belonging to the group Mucorales. It is found in several types of microorganisms. Applications: Chitosanase from streptomyces griseus has been used in a study to assess the effect of chitin sources on production of chitinase and chitosanase. chitosanase from streptomyces griseus has also been used in a study to investigate the effective production of chitinase an...cete aphanomyces euteiches, a major parasite of legume plants. it has also been used for the enzymatic hydrolysis of the fully de-n-acetylated chitosan to get chitosan oligomer mixtures during the preparation of biocompatible chitosan-alginate gel. Group: Enzymes. Synonyms: Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase. Enzyme Commission Number: EC 3.2.1.132. CAS No. 51570-20-8. Chitosanase. Activity: >50 units/mg protein (Bradford). Storage: -20°C. Form: Lyophilized powder containing potassium phosphate buffer salts. Source: Streptomyces griseus. Chitosanase; EC 3.2.1.132; 51570-20-8; Chitosan N-acetylglucosaminohydrolase. Cat No: NATE-0125.
Native Trichoderma harzianum Lysing Enzymes
Native Trichoderma harzianum Lysing Enzymes. Contains β-glucanase, cellulase, protease, and chitinase activities. Applications: Used for yeast spheroplast transformation by hydrolyzing poly (1-3)-glucose of the yeast cell wall glucan. also used to retrieve dna plugs from agarose gels. Group: Enzymes. Synonyms: Lysing Enzymes; Glucanex. Lysing Enzymes. Form: lyophilized powder. Source: Trichoderma harzianum. Lysing Enzymes; Glucanex. Cat No: NATE-0428.
OAT-889
OAT-889 is a dual inhibitor of acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) (hAMCase IC50 = 9 nM;hCHIT1 IC50 = 26 nM), which has the potential to treat asthma. OAT-889 reduced the number of infiltrating leukocytes in bronchoalveolar lavage fluid (BALF) in an acute mouse model of lung inflammation, as well as decreased mRNA of proinflammatory cytokines, such as interleukin-13, interleukin-1 and Muc5AC in lung tissue. Uses: The treatment of asthma. Synonyms: OAT 889; OAT889.
Psammaplin A
Antibiotic. Caffeine-like Ca2+ releaser in heavy sarcoplasmic reticulum (HSR). Antifungal. Chitinase inhibitor. DNA methyltransferase inhibitor. Histone deacetylase (HDAC) inhibitor. Anticancer compound. Angiogenesis suppressor. Group: Biochemicals. Alternative Names: (α E, α 'E) -N, N'- (Dithiodi-2, 1-ethanediyl) bis[3-bromo-4-hydroxy-α - (hydroxyimino) benzenepropanamide]; (E,E)-Psammaplin A; Bisprasin; Psammaplin A; UVI 5000; (E,E)-N,N'-(Dithiodi-2,1-ethanediyl)bis[3-bromo-4-hydroxy-α-(hydroxyimino)-benzenepropanamide]. Grades: Highly Purified. CAS No. 110659-91-1. Pack Sizes: 100ug, 500ug. Molecular Formula: C??H??Br?N?O?S?. US Biological Life Sciences.
Worldwide
Pseurotin A
Pseurotin A is a fungal metabolite with an unusual hetero-spirocyclic ring system. It has been shown to have potent neuritogenic activity in PC12 phaechromocytoma cells, a useful model for adrenergic neuronal differentiation. Pseurotin A induced multipolar and branching neurites comparable to beta-NGF, an endogenous neurotrophic factor. Pseurotin A is also reported to exhibit chitinase inhibition and displays synergistic activity with azole antifungal agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 58523-30-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Resorufin N-acetyl-b-D-glucosamine
Resorufin N-acetyl-b-D-glucosamine is a powerful biomedical tool, playing a crucial role in deciphering and studying multifarious enzymatic responses across diverse pathological conditions. With innate fluorogenic properties, it proficiently serves as a versatile substrate for key enzymes encompassing glucosaminidases, chitinases and glycosidases. Synonyms: Resorufinyl 2-acetamido-2-deoxy-beta-D-glucopyranoside; N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(7-oxophenoxazin-3-yl)oxyoxan-3-yl]acetamide; Resorufin-beta-D-glucosaminide; RNAG [Resorufin N-acetyl-beta-D-glucosamine];7-[[2-(Acetylamino)-2-deoxy-|A-D-glucopyranosyl]oxy]-3H-phenoxazin-3-one. CAS No. 124762-32-9. Molecular formula: C20H20N2O8. Mole weight: 416.38.
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