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| Product | Description | |
|---|---|---|
| 1,4-Dichloro-2-butyne | 1,4-Dichloro-2-butyne used in the synthesis of 1,4-disubstituted 1,2,3-triazoles. Also, it is used in the approach of the 20S-camptothecin family of antitumor agents. Group: Biochemicals. Alternative Names: 1,4-Dichloro-2-butyne; 1,4-Dichlorobutyne; Bis (chloromethyl) acetylene; NSC 30603. Grades: Highly Purified. CAS No. 821-10-3. Pack Sizes: 5g. US Biological Life Sciences. |  Worldwide |
| 1-Amino-4-chloro-2-butyne·HCl | 1-Amino-4-chloro-2-butyne·HCl. Group: Biochemicals. Alternative Names: 4-Chlorobut-2-yn-1-amine hydrochloride. Grades: Highly Purified. CAS No. 77369-59-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C4H6CIN. US Biological Life Sciences. | Worldwide |
| 1-Amino-4-chloro-2-butyne·HCl 98+% (TLC) | 1-Amino-4-chloro-2-butyne·HCl 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| 3-Chloro-1-butyne | 3-Chloro-1-butyne. Group: Charge transfer complexesself assembly and contact printing materials. CAS No. 21020-24-6. Product ID: 3-chlorobut-1-yne. Molecular formula: 88.53g/mol. Mole weight: C4H5Cl. CC(C#C)Cl. InChI=1S/C4H5Cl/c1-3-4(2)5/h1,4H,2H3. PZFBULOUMNPBFA-UHFFFAOYSA-N. >98.0%(GC). |  |
| 3-Chloro-1-butyne, ≥98% | 3-Chloro-1-butyne, ≥98%. Group: Self assembly and contact printing. CAS No. 21020-24-6. Product ID: 3-chlorobut-1-yne. Molecular formula: 88.53g/mol. Mole weight: C4H5Cl. CC(C#C)Cl. InChI=1S/C4H5Cl/c1-3-4(2)5/h1,4H,2H3. PZFBULOUMNPBFA-UHFFFAOYSA-N. | |
| 3-Chloro-3-methyl-1-butyne | 3-Chloro-3-methyl-1-butyne is a propargyl chloride used to alkylate methanol, ethanol, ammonia and amines to the corresponding propargylic ether and amines. Group: Biochemicals. Alternative Names: 2-Chloro-2-methyl-3-butyne; 2-Methyl-2-chloro-3-butyne; 2-Methyl-3-butyn-2-yl chloride; 3-Chloro-3-methylbutyne; 3-Methyl-1-butyn-3-yl chloride; 3-Methyl-3-chloro-1-butyne; 3-Methyl-3-chlorobutyne; NSC 16173; α,α-Dimethylpropargyl Chloride. Grades: Highly Purified. CAS No. 1111-97-3. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| 3-Chloro-3-methyl-1-butyne | Alcohols. CAS No. 1111-97-3. Molecular formula: C11H22O. Mole weight: 102.56. Catalog: ACM1111973. |  |
| 3-Chlorophenylmagnesium bromide | 0.5 M in THF. Uses: 3-chlorophenylmagnesium bromide (o-chlorophnylmagnesium bromide) is a grignard reagent that can be used to synthesize: 2,3-di(o-chlorophenyl)buta-1,3-dienes by reacting with 1,4-dimethoxy 2-butyne in the presence of a copper(I) salt. 2-bromo-5-chlorothiophen-3-yl-(3-chlorophenyl)methanol by reacting with 2-bromo-5-chlorothiophene-3-carbaldehyde. 2-(3-chlorophenyl)-1-phenyl-1h-inden-1-ol from 2- benzoylbenzonitrile as a starting a material. Group: Solvents. Alternative Names: (3-Chlorophenyl)magnesium bromide, (m-Chlorophenyl)magnesium bromide, 3-chloro phenyl magnesium bromide, 3-chlorophenyl magnesium bromide, m-chlorophenyl magnesium bromide, Bromo(3-chlorophenyl)magnesium. CAS No. 36229-42-2. Molecular formula: C6H4BrClMg. Mole weight: 215.76. IUPACName: bromo(3-chlorophenyl)magnesium. Canonical SMILES: ClC1=CC([Mg]Br)=CC=C1. Density: 0.960 g/mL at 25 °C(lit.). Catalog: ACM36229422. | |
| 1-Chloro-4-phenyl-3-butyn-2-one | 1-Chloro-4-phenyl-3-butyn-2-one. Group: Biochemicals. Grades: Highly Purified. CAS No. 176648-09-2. Pack Sizes: 500mg. Molecular Formula: C10H7ClO, Molecular Weight: 178.62. US Biological Life Sciences. | Worldwide |
| ARQ-621 | ARQ-621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Over-expression of Eg5 causes genomic instability and tumor formation in mice. Preclinical data shows anti-tumor activity of ARQ 621 across a wide range of cell lines from human solid and hematological malignancies. Synonyms: NSC-771644; N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluorobenzamide; (R)-N-(3-Aminopropyl)-3-chloro-N-(1-(7-chloro-4-oxo-3-(phenylamino)-3,4-dihydroquinazolin-2-yl)but-3-yn-1-yl)-2-fluorobenzamide; Benzamide, N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluoro-. Grades: ≥95%. CAS No. 1095253-39-6. Molecular formula: C28H24Cl2FN5O2. Mole weight: 552.43. |  |
| Epertinib | Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib; S-22611; S22611; S 22611; (R, Z) -1- (4- ( (3-chloro-4- ( (3-fluorobenzyl) oxy) phenyl) amino) quinazolin-6-yl) but-2-yn-1-one O-morpholin-3-ylmethyl oxime; Epertinib; S-222611; S222611; S 222611; 2-Butyn-1-one, 1-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, O-((3R)-3-morpholinylmethyl)oxime, (1Z)-; N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}- 6-[(1Z)-N-{[(3R)-morpholin-3-yl]methoxy}but- 2-ynimidoyl]quinazolin-4-amine. CAS No. 908305-13-5. Molecular formula: C30H27ClFN5O3. Mole weight: 559.178. | |
| HDS 029 | HDS 029 is a potent inhibitor of the ErbB receptor family including EGFR, ErbB2 and ErbB4 (IC50 = 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2, respectively). HDS 029 inhibits EGF-induced erbB1 autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB autophosphorylation in MDA-MB-453 human breast carcinoma cells (IC50 = 2.5 and 24 nM, respectively). Synonyms: HDS 029; HDS 029; HDS 029; N-(4-[(-3-Chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl-2-butynamide; EGFR/ErbB-2/ErbB-4 Inhibitor. Grades: ≥97% by HPLC. CAS No. 881001-19-0. Molecular formula: C17H11ClFN5O. Mole weight: 355.76. | |
| McNA343 | McNA343 is a partial agonist of muscarinic acetylcholine receptors. It induces contraction of isolated human umbilical veins. Group: Agonists. Alternative Names: McNA343; McN-A343; McN A343; McNA 343; McNA-343; McNA343. CAS No. 55-45-8. Molecular formula: C14H18Cl2N2O2. Mole weight: 317.21. Appearance: Solid powder. Purity: >98%. IUPACName: 4-[[[(3-chlorophenyl)amino]carbonyl]oxy]-N, N, N-trimethyl-2-butyn-1-aminium, monochloride. Canonical SMILES: C[N+] (C) (C)CC#CCOC (NC1=CC=CC (Cl)=C1)=O. [Cl-]. Catalog: ACM55458-1. | |
| McN-A 343 | McN-A 343 is a partial agonist with similar affinity at all five muscarinic acetylcholine receptor subtypes and its relative selectivity depends on a higher efficacy at the M1 (and M4) subtypes. Its selectivity for M1 over other muscarinic receptor types appears to arise from a high efficacy at M1 receptors. Uses: Nicotinic agonists. Synonyms: [4-(m-Chlorophenylcarbamoyloxy)-2-butynyl]trimethylammonium Chloride; 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium Chloride; m-Chlorocarbanilate (4-Hydroxy-2-butynyl)trimethylammonium Chloride; A 343; McN 343; McN-A 343-11. Grades: ≥99% by HPLC. CAS No. 55-45-8. Molecular formula: C14H18Cl2N2O2. Mole weight: 317.21. | |
| (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol | Intermediate in the preparation of Efavirenz impurity. Group: Biochemicals. Alternative Names: (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol; (α S) -2-Amino-5-chloro-α - (cyclopropylethynyl) -α - (trifluoromethyl) benzenemethanol. Grades: Highly Purified. CAS No. 209414-27-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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