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Diazepam Impurity 2 is one of Diazepam impurities. Diazepam is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: N-[[5-Chloro-2- (methylamino) phenyl]phenylmethylene]glycine. Grades: > 98%. CAS No. 102725-59-7. Molecular formula: C16H15ClN2O2. Mole weight: 302.75.
Diazepam Impurity 3
Diazepam Impurity 3 is one of Diazepam impurities. Diazepam is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: N-[[5-Chloro-2- (methylamino) phenyl]phenylmethylene]glycine Methyl Ester. Grades: > 98%. CAS No. 176796-46-6. Molecular formula: C17H17ClN2O2. Mole weight: 316.78.
L-701,324
L-701,324 is a selective antagonist at the glycine site of the NMDA glutamate receptor. L-701,324 shows a beneficial action in the animal model of parkinsonian rigidity. L-701,324 is also a anticonvulsant which has a reduced propensity to activate mesolimbic dopaminergic systems in rodents. Preclinical trials for the treatment of Anxiety disorders, Epilepsy, Major depressive disorder and Psychotic disorders were discontinued. Uses: Anxiety disorders; epilepsy; major depressive disorder; psychotic disorders. Synonyms: L701324; L 701324; L-701324; L701324; L 701324; L-701324; 7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE;7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE. Grades: 98 %. CAS No. 142326-59-8. Molecular formula: C21H14ClNO3. Mole weight: 363.79.
SSR 504734
SSR 504734 is a potent and orally bioactive GlyT-1 inhibitor blocking the ex vivo uptake of glycine reversibly in animal models of schizophrenia, anxiety and depression. Synonyms: D06SBS; SSR 504734; SSR504734; SSR-504734; 2-chloro-N-[(S)-phenyl-[(2S)-piperidin-2-yl]methyl]-3-(trifluoromethyl)benzamide hydrochloride. Grades: 99%. CAS No. 615571-23-8. Molecular formula: C20H20ClF3N2O.HCl. Mole weight: 433.29.
Flucloxacillin Impurity G
An impurity of Flucloxacillin. Flucloxacillin is a narrow-spectrum beta-lactam antibiotic of the penicillin class. Synonyms: (5R)-Flucloxacillin N4-[N-[[3-(2-Chloro-6-fluoro-phenyl)-5-methyl-4-isoxazolyl]carbonyl]-glycinyl] Penilloic Acid. Grades: ≥95%. Molecular formula: C32H27Cl2F2N5O9S. Mole weight: 766.55.
A highly potent and selective antagonist for thenMDA receptor glycine site (IC50 = 2.0nM; Kd = 28nM; ED50 = 0.9nM either intraperitoneal (ip) or oral (po) adminited). The first such compounds with significant activity in the central nervous system following oral dosing and a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 142326-59-8. Pack Sizes: 10mg. US Biological Life Sciences.
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N2,N6-Di-Cbz Avizafone
N2,N6-Di-Cbz Avizafone is one of Diazepam intermediates. Diazepam is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysyl-N-(2-benzoyl-4-chlorophenyl)-N-methyl-glycinamide; benzyl N-[(2S)-1-[[2-(2-benzoyl-4-chloro-N-methylanilino)-2-oxoethyl]amino]-1-oxo-6-(phenylmethoxycarbonylamino)hexan-2-yl]carbamate; (Nalpha, Nepsilon-bisbenzyloxycarbonyl-L-lysyl)-N-(2-benzoyl-4-chlorophenyl)-N-methylglycinamide; (S)-dibenzyl (6-((2-((2-benzoyl-4-chlorophenyl)(methyl)amino)-2-oxoethyl)amino)-6-oxohexane-1,5-diyl)dicarbamate. Grades: ≥95%. CAS No. 60067-14-3. Molecular formula: C38H39ClN4O7. Mole weight: 699.19.
(SP-4-4)-[N-[[5-Chloro-2-[[[ (1S, 2R)-1- (phenylmethyl)-2-pyrrolidinyl-κ N]carbonyl]amino-κ N]phenyl]phenylmethylene]glycinato (2-)-κ N, κ O]-nickel
A negative allosteric modulator selective for NR2A containingnMDA receptors (pIC50 = 6.8 and <4.3uM for NR2A and NR2B, respectively). No effect on NR2B-containingnMDA receptors with concentrations less than 50 mM. Inhibition on NR2A containingnMDA receptors is glycine (or D-serine)-binding, but not glutamate-binding, dependent. Group: Biochemicals. Grades: Highly Purified. CAS No. 852918-02-6. Pack Sizes: 5mg. US Biological Life Sciences.
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