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Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase ( IC 50 =65 nM) by binding to the allosteric site on the regulatory subunit [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123318-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-A0005.
Clofarabine
Clofarabine. Group: Biochemicals. Grades: Purified. CAS No. 123318-82-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Clofarabine
Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. Synonyms: 6-Amino-2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine; CAFdA; 6-Amino-2-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside; C1-F-Ara-A; Clofarex; 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine; Clolar; Evoltra; 2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)adenine. Grades: ≥95%. CAS No. 123318-82-1. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68.
ISecond generation purine nucleoside analog; antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Group: Biochemicals. Alternative Names: 2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine; Clolar. Grades: Highly Purified. CAS No. 123318-82-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Clofarabine-5'-monophosphate
Clofarabine-5'-monophosphate is a prodrug form of clofarabine, an anti-cancer agent used to treat pediatric acute lymphoblastic leukemia and adult refractory or relapsed acute myeloid leukemia. It quickly converts into clofarabine-5'-triphosphate, which inhibits DNA synthesis and induces apoptosis in cancer cells. Grades: ≥ 95% by HPLC. CAS No. 134646-42-7. Molecular formula: C10H12ClFN5O6P (free acid). Mole weight: 383.66 (free acid).
Clofarabine 5'-monophosphate triethyammonium salt
Clofarabine 5'-monophosphate triethyammonium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
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Clofarabine-5'-triphosphate
Clofarabine-5'-triphosphate is an inhibitor of human ribonucleotide reductase that alter the quaternary structure of its large subunit. It has an anticancer activity. Uses: Clofarabine-5'-triphosphate is an inhibitor of human ribonucleotide reductase. Grades: ≥ 95% by HPLC. CAS No. 167620-89-5. Molecular formula: C10H14ClFN5O12P3 (free acid). Mole weight: 543.62 (free acid).
Clofarabine 5'-triphosphate triethyammonium salt
Clofarabine 5'-triphosphate triethyammonium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
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Clofarabine Hydrolyzed Impurity 1
Clofarabine Hydrolyzed Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Clofarabine Hydrolyzed Impurity 1. Molecular Formula: C10H13ClFN5O4. Mole Weight: 321.69. Catalog: APB04636.
Clofarabine Impurity 1
Clofarabine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4R,5R)-5-((benzoyloxy)methyl)-3-fluorotetrahydrofuran-2,4-diyl dibenzoate. CAS No. 704916-12-1. Molecular Formula: C26H21FO7. Mole Weight: 464.44. Catalog: APB704916121.
Clofarabine Impurity 10
Clofarabine Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4S,5R)-5-(2-chloro-6-(((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)amino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 1093278-53-5. Molecular Formula: C15H18ClF2N5O6. Mole Weight: 437.78. Catalog: APB1093278535.
Clofarabine Impurity 11
Clofarabine Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4S,5R)-5-(2-chloro-6-(((2S,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)amino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 1093278-54-6. Molecular Formula: C15H18ClF2N5O6. Mole Weight: 437.78. Catalog: APB1093278546.
Clofarabine Impurity 12
Clofarabine Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4S,5R)-5-((6-amino-2-chloro-5-formamidopyrimidin-4-yl)amino)-2-((benzoyloxy)methyl)-4-fluorotetrahydrofuran-3-yl benzoate. Molecular Formula: C24H21ClFN5O6. Mole Weight: 529.90. Catalog: APB04631.
Clofarabine Impurity 13
Clofarabine Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloropyrimidine-4,5,6-triamine. CAS No. 40928-86-7. Molecular Formula: C4H6ClN5. Mole Weight: 159.58. Catalog: APB40928867.
Clofarabine Impurity 15
Clofarabine Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,6-dichloro-9-nitroso-9H-purine. Molecular Formula: C5HCl2N5O. Mole Weight: 218.00. Catalog: APB04630.
Clofarabine Impurity 16
Clofarabine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-amino-9-((2S,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one. CAS No. 899827-82-8. Molecular Formula: C10H12FN5O4. Mole Weight: 285.23. Catalog: APB899827828.
Clofarabine Impurity 17
Clofarabine Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Clofarabine Impurity 17. Molecular Formula: C15H14ClFN10O3. Mole Weight: 436.79. Catalog: APB04629.
Clofarabine Impurity 3
Clofarabine Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R,3R,4S)-4-((2-chloro-9-((2R,3S,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)-3-fluorocyclohexane-1,2-diol. Molecular Formula: C16H20ClF2N5O5. Mole Weight: 435.81. Catalog: APB04635.
Clofarabine Impurity 4
Clofarabine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4R,5R)-2-acetoxy-5-((benzoyloxy)methyl)tetrahydrofuran-3,4-diyl dibenzoate. CAS No. 70832-64-3. Molecular Formula: C28H24O9. Mole Weight: 504.48. Catalog: APB70832643.
Clofarabine Impurity 5
Clofarabine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4R,5R)-2-acetoxy-5-((benzoyloxy)methyl)tetrahydrofuran-3,4-diyl dibenzoate. CAS No. 14215-97-5. Molecular Formula: C28H24O9. Mole Weight: 504.48. Catalog: APB14215975.
Clofarabine Impurity 6
Clofarabine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4R,5R)-5-((benzoyloxy)methyl)-3-fluorotetrahydrofuran-2,4-diyl dibenzoate. CAS No. 97614-43-2. Molecular Formula: C26H21FO7. Mole Weight: 464.44. Catalog: APB97614432.
Clofarabine Impurity 7
Clofarabine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Clofarabine Impurity 7. Molecular Formula: C10H13ClFN5O4. Mole Weight: 321.69. Catalog: APB04634.
Clofarabine Impurity 8
Clofarabine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4R,5S,6R)-6-((2-chloro-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)-5-fluorotetrahydro-2H-pyran-3,4-diol. Molecular Formula: C15H18ClF2N5O6. Mole Weight: 437.78. Catalog: APB04633.
Clofarabine Impurity 9
Clofarabine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4R,5S,6S)-6-((2-chloro-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)-5-fluorotetrahydro-2H-pyran-3,4-diol. Molecular Formula: C15H18ClF2N5O6. Mole Weight: 437.78. Catalog: APB04632.
Clofarabine Triphosphate Triethylamine Salt
Clofarabine Triphosphate Triethylamine Salt is a metabolite of Clofarabine. Synonyms: 2-Chloro-9-[2-deoxy-2-fluoro-5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-arabinofuranosyl]-9H-purin-6-amine Triethylamine Salt. Molecular formula: C10H14ClFN5O12P3 X(C6H15N). Mole weight: 543.62.
α-Clofarabine
α-Clofarabine is a second generation purine nucleoside analog; antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Synonyms: 2-Chloro-9-(2-deoxy-2-fluoro-α-D-arabinofuranosyl)-9H-purin-6-amine. CAS No. 491594-60-6. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68.
1,3,5-Tri-O-benzoyl-2-O-(1H-imidazol-1-ylsulfonyl)-alpha-D-ribofuranose is used in the preparation of clofarabine (nucleoside analog) for cancer treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 97614-42-1. Pack Sizes: 1g, 5g. Molecular Formula: C29H24N2O10S, Molecular Weight: 592.57. US Biological Life Sciences.
Worldwide
1,3,5-Tri-O-benzoyl-a-D-ribofuranose
It is a reagent for nucleosides and is used in the synthesis of antileukemia drug Clofarabine. Synonyms: a-D-Ribofuranose 1,3,5-tribenzoate; 1,3,5-Tribenzoate-α-D-ribofuranose; 1,3,5-Tribenzoate Ribofuranose; α-D-1,3,5-Tri-O-benzoyl-ribofuranose; (2R,3R,4S,5R)-5-(benzoyloxymethyl)-3-hydroxytetrahydrofuran-2,4-diyl dibenzoate. Grades: ≥98% by HPLC. CAS No. 22224-41-5. Molecular formula: C26H22O8. Mole weight: 462.45.
1,3,5-Tri-O-benzoyl-α-D-ribofuranose
1,3,5-Tri-O-benzoyl-α-D-ribofuranose is a reagent for nucleosides and it is used in the synthesis of antileukemia drug Clofarabine (C586890). 1,3,5-Tri-O-benzoyl-α-D-ribofuranose is a carbohydrate intermediate. Group: Biochemicals. Grades: Highly Purified. CAS No. 22224-41-5. Pack Sizes: 1g, 5g. Molecular Formula: C26H22O8, Molecular Weight: 462.45. US Biological Life Sciences.
Worldwide
2',3'-O-Isopropylideneadenosine
2',3'-O-Isopropylideneadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 362-75-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W008048.
2-Aminoadenosine
2-Aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2096-10-8. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W011548.
2-Chloro-9-(2-chloro-2-deoxy- β-D-arabinofuranosyl)purin-6-amine is used in the synthetic preparation of impurities and degradants from clofarabine process. Group: Biochemicals. Grades: Highly Purified. CAS No. 111615-20-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C10H11Cl2N5O3, Molecular Weight: 320.13. US Biological Life Sciences.
Worldwide
2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine
It is the impurity B of Clofarabine and a DNA and RNA synthetase inhibitor. Synonyms: 2'-Deoxy-2'-fluoro-arabinoisoguanosine; 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine; 6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one; 6-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-2H-purin-2-one. Grades: ≥95%. CAS No. 899827-82-8. Molecular formula: C10H12FN5O4. Mole weight: 285.23.
2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine
It is the impurity C of Clofarabine and is also an anticancer agent. Synonyms: 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine; 2-Amino-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1H-purin-6(9H)-one; 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 103884-98-6. Molecular formula: C10H12FN5O4. Mole weight: 285.23.
2-Iodoadenosine
2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35109-88-7. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-W008552.
It can be used in the synthesis of Clofarabine. Synonyms: 2-Deoxy-2-fluoro-a-D-arabinofuranosyl bromide 3,5-dibenzoate; 2-Deoxy-2-fluoro-α-D-arabinofuranosyl Bromide Dibenzoate; 2-deoxy-2-fluoro-3,5-di-o-benzoyl-alpha-d-arabinofuranosyl bromide; 2-Deoxy-2-fluoro-3-O,5-O-dibenzoyl-alpha-D-arabinofuranosyl bromide; ((2R,3R,4S,5R)-3-(Benzoyloxy)-5-bromo-4-fluorotetrahydrofuran-2-yl)methyl benzoate. Grades: ≥97% by HPLC. CAS No. 97614-44-3. Molecular formula: C19H16BrFO5. Mole weight: 423.24.
3-O-Methyladenosine
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol (Adenosine, 3'-O-methyl- (8CI)(9CI)) is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10300-22-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W393243.
(3S,4S,5R)-6-(6-Amino-2-chloro-9H-purin-9-yl)-5-fluorotetrahydro-2H-pyran-3,4-diol is an impurity of Clofarabine, Second generation purine nucleoside analog, antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Synonyms: Clofarabine Impurity. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68.
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5'-O-(4,4'-DIMETHOXYTRITYL)ADENOSINE. CAS No. 81352-25-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-W097775.
6-Amino-2-chloro-9-(2'-deoxy-2-fluoro-3',5'-di-O-benzoyl-β-D-arabinofuranosyl)-9H-purine is an intermediate in the synthesis of N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-β-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide which is a clofarabine related compound. Clofarabine is a second generation purine nucleoside analog, and antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Synonyms: 2-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine. CAS No. 355138-50-0. Molecular formula: C24H19ClFN5O5. Mole weight: 511.89.
6-Amino-2-chloro-9- (2'-deoxy-2'-fluoro-b-D-arabinofuranosyl) purine. Group: Biochemicals. Alternative Names: Clofarabine; 2-Chloro-6-amino-purine-2'-fluoro-2'-deoxy arabinoside. Grades: Highly Purified. CAS No. 123318-82-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C10H11ClFN5O3. US Biological Life Sciences.
Worldwide
8-Bromoadenosine
8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2946-39-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W013195.
N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-α-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide is a clofarabine related compound. Clofarabine is a second generation purine nucleoside analog, antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Synonyms: N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-alpha-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide; N-[4-Amino-2-chloro-6-[[(2S,3S,4R,5R)-3-fluoro-4,5-dihydroxyoxan-2-yl]amino]pyrimidin-5-yl]formamide. Grades: 95%. CAS No. 1140251-30-4. Molecular formula: C10H13ClFN5O4. Mole weight: 321.69.
N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-β-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide is a clofarabine related compound. Clofarabine is a second generation purine nucleoside analog and antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Synonyms: N-(4-Amino-2-chloro-6-(((2R,3S,4R,5R)-3-fluoro-4,5-dihydroxytetrahydro-2H-pyran-2-yl)amino)pyrimidin-5-yl)formamide. Grades: 95%. CAS No. 1140251-33-7. Molecular formula: C10H13ClFN5O4. Mole weight: 321.69.
N-[4-Amino-2-chloro-6-[(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)amino]-5-pyrimidinyl]-formamide is an intermediate in the synthesis of N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-β-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide which is a clofarabine related compound. Clofarabine is a second generation purine nucleoside analog, antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. CAS No. 1140251-41-7. Molecular formula: C24H21ClFN5O6. Mole weight: 529.9.
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