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| Product | Description | |
|---|---|---|
| Clonidine hydrochloride | Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent. Uses: Scientific research. Group: Signaling pathways. CAS No. 4205-91-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0409A. |  |
| Clonidine Hydrochloride | α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain. Group: Biochemicals. Alternative Names: N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine Hydrochloride; 2-(2,6-Dichloroanilino)-2-imidazoline Hydrochloride; Atensina; Capresin; Catapres; Haemiton; Hemiton; Isoglaucon; Katapresan; Neuclon; Normopresan; ST 155. Grades: Highly Purified. CAS No. 4205-91-8. Pack Sizes: 1g, 5g. US Biological Life Sciences. |  Worldwide |
| Clonidine Hydrochloride | Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg. Uses: Sympatholytics. Synonyms: N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine Hydrochloride; 2-(2,6-Dichloroanilino)-2-imidazoline Hydrochloride; Atensina; Capresin; Catapres; Haemiton; Hemiton; Isoglaucon; Katapresan; Neuclon; Normopresan; ST 155. Grades: >98%. CAS No. 4205-91-8. Molecular formula: C9H9Cl2N3.HCl. Mole weight: 266.5. |  |
| 4-Hydroxy Clonidine Hydrochloride | 4-Hydroxy Clonidine is a metabolite of Clonidine, an α2-Adrenergic agonist. Synonyms: 3,5-Dichloro-4-[(4,5-dihydro-1H-imidazol-2-yl)amino]phenol Hydrochloride; p-Hydroxyclonidine Hydrochloride; ST 666 Hydrochloride. Grades: > 95%. CAS No. 86861-28-1. Molecular formula: C9H10Cl3N3O. Mole weight: 282.55. | |
| Apraclonidine hydrochloride | Apraclonidine is an α2-adrenergic receptor (α2-AR) agonist and structural analog of clonidine. It is used for the treatment of post-surgical elevated intraocular pressure. It inhibits noradrenaline-stimulated contraction in guinea pig ileum with EC50s of 7.59 nM and rabbit vas deferens with EC50s of 6.76 nM. Uses: Adrenergic alpha-2 receptor agonists. Synonyms: ALO 2145; 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine hydrochloride; Iopidine; p-Aminoclonidine monohydrochloride. Grades: ≥98%. CAS No. 73218-79-8. Molecular formula: C9H10Cl2N4·HCl. Mole weight: 281.6. | |
| Apraclonidine Hydrochloride | α-Adrenergic agonist; structural analog of clonidine. Used for treatment of post-surgical elevated intraocular pressure. Group: Biochemicals. Alternative Names: 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine Hydrochloride; Iopidine; p-Aminoclonidine Monohydrochloride; AL 02145; ALO 2145. Grades: Highly Purified. CAS No. 73218-79-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C?H??Cl?N?, Molecular Weight: 281.57. US Biological Life Sciences. | Worldwide |
| Clonidine-d4 Hydrochloride (N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-d4-2-amine, 2-(2,6-Dichloroanilino)-2-imidazoline-d4, ST-155-d4, Catapres-d4, Catapresan-d4) | a2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain. Group: Biochemicals. Alternative Names: N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-d4-2-amine; 2-(2,6-Dichloroanilino)-2-imidazoline-d4; ST-155-d4; Catapres-d4; Catapresan-d4. Grades: Highly Purified. CAS No. 67151-02-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| p-Iodo-clonidine hydrochloride | p-Iodo-clonidine is a partial antihypertensive α2-adrenergic receptor agonist. It potentiates platelet aggregation by ADP and inhibits epinephrine-induced aggregation. Uses: Affinity labels. Synonyms: p-Iodoclonidine hydrochloride; 2-[(2,6-Dichloro-4-iodophenyl)imino]imidazoline hydrochloride; N-(2,6-dichloro-4-iodophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride. Grades: ≥98%. CAS No. 108294-57-1. Molecular formula: C9H8Cl2IN3·HCl. Mole weight: 392.5. | |
| Lofexidine hydrochloride | Lofexidine hydrochloride is the hydrochloride salt form of Lofexidine. Lofexidine, an analogue of clonidine, is an α2A-adrenergic receptor agonist for the treatment of opioid withdrawal symptoms as well as an anihypertensive. Uses: α2-adrenoceptor agonist related structurally to clonidine. used in treatment of opioid withdrawal symptoms; antihypertensive. Synonyms: 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole;hydrochloride 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline BritLofex lofexidine lofexidine hydrochloride Lofexidine mono-hydrochloride lofexidine monohydrochloride lofexidine, (+-)-isom. Grades: ≥98%. CAS No. 21498-08-8. Molecular formula: C11H13Cl3N2O. Mole weight: 295.59. | |
| Moxonidine hydrochloride | Moxonidine hydrochloride is a mixed agonist of α2-adrenergic receptor (α2AR) and imidazoline-1 receptor(I1R). Its Ki values is 4.2±3.2 nmol/L, 13.0±4.2 nmol/L, 9.5±4.1 nmol/L and 15.6±9.8 nmol/L for I1R, α2AAR, α2BAR and α2CAR, respectively. It is used as antihypertensive agent. It displays 40-fold higher affinity for I1 receptors versus α2-adrenoceptors. It reduced stimulated NE overflow (log EC50: -6.15 +/- 0.14). It has been reported to produce dose-dependent analgesia in multiple acute pain assays and has been reported to potently inhibit the binding of [3H]-clonidine to VLM (ventrolateral medulla) membranes in a dose-dependent manner with the IC50 value of 53 ± 10nM. It has shown low affinity for I2-relative to I1R sites in bovine adrenal medullary cells. Uses: Moxonidine hydrochloride is used as antihypertensive agent. it has been reported to produce dose-dependent analgesia in multiple acute pain assays and has been reported to potently inhibit the binding of [3h]-clonidine to vlm (ventrolateral medulla) membranes in a dose-dependent manner with the ic50 value of 53 ± 10nm. Synonyms: BDF5895 hydrochloride; BDF 5895 hydrochloride; BDF-5895 hydrochloride; 4-Chloro-6-methoxy-2-methyl-5-(2-imidazolin-2-yl)aminopyrimidine hydrochloride. Grades: 98%. CAS No. 75536-04-8. Molecular formula: C9H13Cl2N5O. Mole weight: 278.14. | |
| Oxymetazoline Hydrochloride | Vasoconstrictor, used as a nasal decongestant. An ingredient of Drixin. Oxymetazoline is an agonist of α1- and α2-adrenergic receptors (α1- and α2-ARs; Kds = 6, 320, and 390 nM for α1A-, α1B-, and α1D-ARs, respectively, Ki = 15 nM for α2-AR).1,2 It is also an agonist of the serotonin (5-HT) receptor subtype 5-HT1 (Kds = 4.68, 25.7, and 5.01 nM for 5-HT1A, 5-HT1B, and 5-HT1D, respectively).3 Oxymetazoline increases intracellular calcium levels in CHO cells transfected with the α1A-AR (EC50 = 40.7 nM), but does not increase it measurably in cells transfected with the α1B- or α1D-AR (EC50s = 79.4 and 240 nM, respectively).1 It acts as a partial agonist of the α2-AR in isolated perfused rat heart (IC50 = 63 nM and EC50 = 13.5 nM for norepinephrine release).4,5 Oxymetazoline also acts as an agonist and antagonist of the 5-HT1C receptor in the presence of methiothepin (Kd = 110 nM; Item No. 23138) and clonidine (Kd = 257 Group: Biochemicals. Alternative Names: 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol Hydrochloride; 2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline Hydrochloride; 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol Hydrochloride; Hazol; Navasin; Navisin; Nezeril; Oxylazine; Rhinofrenol; Rhinolitan; Sinerol. Grades: Highly Purified. CAS No. 2315-2-8. Pack Sizes: 100mg, 500mg, 1g, 5g. Molecular Formula: C??H??ClN?O, Molecular Weight: 296.84. US Biological Life Sciences. | Worldwide |
| Lofexidine-d4 Hydrochloride | α2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive. Group: Biochemicals. Alternative Names: 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-. Grades: Highly Purified. CAS No. 78302-26-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Lofexidine, Hydrochloride (MDL-14042A, Ba-168, Britlofex, Lofetensin,Loxacor) | A vasoactive agent related structurally to Clonidine. Group: Biochemicals. Alternative Names: MDL-14042A, Ba-168, Britlofex, Lofetensin,Loxacor. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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