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It is produced by the strain of Bipolaris zeicila. Cochlioquinone A inhibited DGAT with IC50 of 5.6 μg/mL. Synonyms: Coclioquinone A; Pyrano[3,2-a]xanthene-8,11-dione,9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-,(3R,4aR,6aR,12S,12aS,12bR)-; Luteoleersin. Grades: >99% by HPLC. CAS No. 32450-25-2. Molecular formula: C30H44O8. Mole weight: 532.66.
Cochlioquinone A1
It is produced by the strain of Bipolaris zeicila. Cochlioquinone A1 inhibited DGAT with IC50 of 6.3 μg/mL. Molecular formula: C33H50O9. Mole weight: 590.74.
Cochlioquinone A (Luteoleersin)
Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Cochlioquinone A has been recently shown to be an antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1). It is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADH-ubiquinone reductase. Group: Biochemicals. Alternative Names: Luteoleersin. Grades: Highly Purified. CAS No. 32450-25-2. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Epi-cochlioquinone A
It is produced by the strain of Stachybitrys bisbyi. It can inhibit rat liver microsomal ACAT with IC50 of 1.7 μmol/L, inhibit plasma lecithin cholesterol acyltransferase (LCAT) with IC50 of 15.8 μmol/L, and inhibit cholesterol absorption in rats by 50% at 75 mg/kg. Synonyms: Epicochlioquinone A; (8-alpha)-Cochlioquinone A; Cochlioquinone A, (8-alpha)-. CAS No. 147384-57-4. Molecular formula: C30H44O8. Mole weight: 532.67.
Cochlioquinone B
Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and a phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A that inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have been recently shown to be antagonists of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1). Group: Biochemicals. Grades: Highly Purified. CAS No. 32450-26-3. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Cochlioquinone B
It is the minor component of a bioactive pigment isolated from Bipolaris cynodontis and Cochliobolus miyabeanus. It is an NADH-ubiquinone reductase inhibitor. It is also a phytotoxic agent inhibiting root growth. It is closely related to cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. It is an antagonist of the human chemokine receptor, CCR5, in HIV-1. Synonyms: 20-De(acetyloxy)-11-deoxy-20-oxo-cochlioquinone A; 9-(1, 3-Dimethyl-2-oxopentyl)-1, 2, 3, 4aα, 5, 6, 6a, 12, 12aα, 12b-decahydro-3β-(1-hydroxy-1-methylethyl)-6aβ, 12bβ-dimethyl-pyrano[3, 2-a]xanthene-8, 11-dione Stereoisomer; (3R,4aR,6aR,12aR,12bR)-9-[(1S,3S)-1,3-Dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethylpyrano[3,2-a]xanthene-8,11-dione. Grades: >99% by HPLC. CAS No. 32450-26-3. Molecular formula: C28H40O6. Mole weight: 472.61.
Cochlioquinone D
Cochlioquinone D is a flavonoid that acts as an antibacterial and antioxidant, and it increases the resistance of rice to the white-backed planthopper (WBPH). CAS No. 173355-88-9. Molecular formula: C28H38O6. Mole weight: 470.60.
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