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Comu. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate;4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate;1-[1-(Cyano-2-ethoxy-2-oxoethylideneaMinooxy)-diMethylaMino-Morpholino]-uroniuM hexafluorophosphate;(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.);COMU(R) 97%;elagolix intermediate 13;COMU 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium. Product Category: Heterocyclic Organic Compound. CAS No. 1075198-30-9. Molecular formula: C12H19N4O4.PF6. Mole weight: 0. Product ID: ACM1075198309. Alfa Chemistry ISO 9001:2015 Certified. Categories: Communism.
COMU
COMU is used as an efficient coupling agent in phosphonamidation reactions; used as coupling reagent in the synthesis of solid phase peptide. Synonyms: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy) dimethylaminomorpholinocarbenium Hexafluorophosphate; (1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate; 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate; COMU(R); Elagolix intermediate 13. Grades: > 98 % (HPLC). CAS No. 1075198-30-9. Molecular formula: C12H19F6N4O4P. Mole weight: 428.27.
COMU®
Fast coupling efficiency, very low or non-existent tendencies for racemization. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: (1-Cyano-2-ethoxy-2-Oxoethylidenaminooxy) Dimethylamino-morpholino-carbenium hexafluorophosphate. CAS No. 1075198-30-9. registered patent of Luxembourg Bio Technologies.
4-{{[ (1-Cyano-2-ethoxy-2-oxoethylidene) amino]oxayl] (dimethylamino) methylene]-hexafluorophosphate. Group: Biochemicals. Alternative Names: COMU. Grades: Highly Purified. CAS No. 1075198-30-9. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C12H19F6N4O4P. US Biological Life Sciences.
Worldwide
HDMC
HDMC is a reagent used in preparation of COMU as a more effective peptide coupling reagent than benzotriazole-based uronium compounds in peptide synthesis. Synonyms: HDMC; 6-HDMCB; (5-Chloro-3-oxo-1H-1lambda-5,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphate; SCHEMBL21223097; DTXSID00746375; BCP29166; N-[(5-Chloro-3-oxido-1H-benzotriazol-1-yl)-4-morpholinylmethylene]-N-methylmethanaminium hexafluorophosphate. Grades: > 95 % (HPLC). CAS No. 1082951-62-9. Molecular formula: C13H17ClF6N5O2P. Mole weight: 455.72.
Musk ketone
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81-14-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2045.
Musk ketone
Musk ketone (MK) is a widely used artificial fragrance. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Acetyl-5-tert-butyl-4,6-dinitroxylene. Product Category: Inhibitors. Appearance: Solid. CAS No. 81-14-1. Molecular formula: C14H18N2O5. Mole weight: 294.3. Purity: 0.99. IUPACName: 1-(4-Tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone. Canonical SMILES: CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N+](=O)[O-])C)C(=O)C. Density: 1.2051 g/cm³. Product ID: ACM81141. Alfa Chemistry ISO 9001:2015 Certified.
PyOxim
PyOxim is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents. Synonyms: pyoxime; AS-10531; SC-13336; CS-0068035; K-4853; J-009012; (Ethyl cyano(hydroxyimino)acetato)-tri-(1-pyrrolidinyl)-phosphonium hexafluorophosphate; [cyano- (ethoxycarbonyl) methyleneaminooxy]tris (1-pyrrolidinyl) phosphonium hexafluorophosphate; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)?-[ethyl 2-cyano-2-[(hydroxy-κO)?imino]?acetato]?tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(?1-). Grades: > 98% (HPLC). CAS No. 153433-21-7. Molecular formula: C17H29F6N5O3P2. Mole weight: 527.38.
PyOxim®
Highly efficient coupling reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: [Ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinylphosphonium hexafluorophosphate. CAS No. 153433-21-7.
Luxembourg Bio Technologies
TOTU
The use of TOTU is possible both in classical peptide synthesis and in solid-phase peptide synthesis, belongs to the same family of COMU and HOTU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O- [ (Ethoxy carbonyl) Cyanomethylenamino] -N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 136849-72-4.
Luxembourg Bio Technologies
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