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Concanavalin A. Group: Biochemicals. Grades: Highly Purified. CAS No. 11028-71-0. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C15H24. US Biological Life Sciences.
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Concanavalin A
Concanavalin A is a Ca 2+ /Mn 2+ -dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury [1] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 11028-71-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2149.
1-Indanone
1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces. Group: Biochemicals. Alternative Names: Indanone; 1-Indone; 1H-Indan-1-one; 2,3-Dihydro-1-indenone; 2,3-Dihydro-1H-inden-1-one; 3-Dihydro-1H-inden-1-one; NSC 2581; α-Hydrindone; α-Indanone. Grades: Highly Purified. CAS No. 83-33-0. Pack Sizes: 25g. US Biological Life Sciences.
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1-Methylindan
1-Methylindan is a component of fuels that is synthesized from 1-indanone (I499900). 1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces. Group: Biochemicals. Grades: Highly Purified. CAS No. 767-58-8. Pack Sizes: 100mg, 1g. Molecular Formula: C10H12. US Biological Life Sciences.
Worldwide
6-Phenanthridone
6-Phenanthridone is a poly(ADP-ribose) polymerase (PARP) inhibitor with immunosuppressive effects. 6-Phenanthridone has been shown to inhibit concanavalin A-induced lymphocyte proliferation. Group: Biochemicals. Alternative Names: 5H-Phenanthridin-6-one; 6-Phenanthridinol; 6-Phenanthridinone; 6-Phenanthridone; NSC 11021; NSC 40943; NSC 61083; PJ 97A; 6(5H)-Phenanthridinone; WD 99-004344. Grades: Highly Purified. CAS No. 1015-89-0. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Antibiotic 2-11-A
It is produced by the strain of Streptomyces sp. 2-11. It can inhibit the proliferation of splenic lymphocytes induced by Concanavalin A in mice. Synonyms: Gibbestatin A; Benzoic acid, 2-hydroxy-6-[5-(1-methoxyethyl)-7-[(3-methyloxiranyl)methylene]-6-oxo-1,3-nonadienyl]-; 2-11-A. CAS No. 89687-35-4. Molecular formula: C23H28O6. Mole weight: 400.46.
Cerebroside D
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Cerebroside D is a glycoceramide compound with antitumor activity. Study on murine experimental colitis showed that cerebroside D reduced weight loss and the macroscopic as well as microscopic appearances of colitis induced by dexran sulfate sodium. Cerebroside D also inhibited proliferation and induced apoptosis of T cells activated by concanavalin A or anti-CD3 plus anti-CD28 antibodies. Synonyms: (2S,2'R,3R,4E,8E)-N-2'-hydroxyoctadecanoyl-1-O-(β-D-glucopyranosyl)-9-methyl-4,8-sphingadienine; (R)-2-Hydroxy-octadecanoic acid [(3E,7E)-(1S,2R)-2-hydroxy-8-methyl-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl)-heptadeca-3,7-dienyl]-amide. Grades: 96.5%. CAS No. 113773-89-0. Molecular formula: C43H81NO9. Mole weight: 756.117.
Native Porcine Diamine Oxidase
Diamine oxidase from porcine kidney is a homodimer consisting of 2 equal subunits with a molecular weight of 87 kDa each. Each subunit contains one molecule of pyridoxal phosphate and one atom of copper. The molecular mass of the enzyme is found to be 170 kDa. The enzyme is a glycoprotein containing 5% hexose, 3.3% glucosamine, 2.6% N-acetylglucosamine, and 0.25% N-acetylneuraminic acid. The enzyme exhibits a high affinity for concanavalin A. It catalyzes the oxidation of monoamines, diamines, and histamine to aldehydes, ammonia, and hydrogen peroxide. Optimum pH with cadverine and histamine as substrates is found to be 6.3-7.4.2 The enzyme is classified as a copper amine oxid...a luminescence-based test for determining ornithine decarboxylase activity. diamine oxidase from porcine kidney has also been used in a study to investigate n-linked oligosaccharide structures in diamine oxidase. Group: Enzymes. Synonyms: EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); Diamine Oxidase; Amine oxidase (copper-containing). Enzyme Commission Number: EC 1.4.3.6. CAS No. 9001-53-0. Diamine Oxidase. Activity: > 0.05 unit/mg solid. Storage: -20°C. Source: Porcine kidney. Species: Porcine. EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); Diamine Oxidase; Amine oxidase (copper-containing).
Remisporine B
Remisporine B is a polyketide and a derivative of remisporine A produced by the strain of Penicillium and has immunosuppressant activity. It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 μg/ml, respectively). Synonyms: Remisporine B; 571194-06-4; AKOS040755735; Dimethyl (1S, 12S, 14S, 15R, 27R)-8, 14, 23-trihydroxy-6, 21-dimethyl-10, 25-dioxo-3, 13, 18-trioxaheptacyclo[13.11.1.02, 11.04, 9.012, 27.017, 26.019, 24]heptacosa-2(11), 4, 6, 8, 17(26), 19, 21, 23-octaene-12, 14-dicarboxylate. Grades: >95% by HPLC. CAS No. 571194-06-4. Molecular formula: C30H24O12. Mole weight: 576.50.
Soyasapogenol A
Soyasapogenol A, a triterpene compound, isolated from soybean. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model. Group: Inhibitors. CAS No. 508-01-0. Molecular formula: C30H50O4. Mole weight: 474.7. Appearance: Powder. Purity: 0.98. IUPACName: (3R, 4S, 4aR, 6aR, 6aS, 6bR, 9S, 10S, 12aR, 14bR)-9-(hydroxymethyl)-2, 2, 4a, 6a, 6b, 9, 12a-heptamethyl-1, 3, 4, 5, 6, 6a, 7, 8, 8a, 10, 11, 12, 13, 14b-tetradecahydropicene-3, 4, 10-triol. Canonical SMILES: CC1 (CC2C3=CCC4C5 (CCC (C (C5CCC4 (C3 (CCC2 (C (C1O)O)C)C)C) (C)CO)O)C)C. Catalog: ACM508010.
Sydowinin B
Sydowinin B is a xanthone polyketide originally isolated from A. sydowii and has immunosuppressant activity. It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20.8 μg/ml, respectively). Synonyms: MS-347b. Grades: >95% by HPLC. CAS No. 58450-00-3. Molecular formula: C16H12O7. Mole weight: 316.26.
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