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An inhibitor of COX-2. Synonyms: Methyl [5-methylsulfonyl-1-(4-chlorobenzyl)-1H-2-indolyl]carboxylate; LM-1685; LM 1685; LM1685. CAS No. 416901-58-1. Molecular formula: C18H16ClNO4S. Mole weight: 377.8.
COX-2 Inhibitor I - CAS 416901-58-1
The COX-2 Inhibitor I, also referenced under CAS 416901-58-1, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 416901-58-1. Pack Sizes: 5MG. Mole Weight: 377.84. Catalog: AP416901581. Assay: ≥97% (HPLC).
COX-2 Inhibitor II
A selective inhibitor of COX-2. Synonyms: SC-791; IN1371; 181696-33-3; 4-[(5-Difluoromethyl-3-phenyl)-4-isoxazolyl]benzenesulfonamide; SCHEMBL214781. CAS No. 181696-33-3. Molecular formula: C16H12F2N2O3S. Mole weight: 350.34.
COX-2 Inhibitor V, FK3311
COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID. Group: Biochemicals. Grades: Highly Purified. CAS No. 116686-15-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H13F2NO4S, Molecular Weight: 341.33. US Biological Life Sciences.
1, 1, 1-Trifluoromethane sulfonic Acid 2-(2-Propen-1-yl)phenyl Ester is an protected intermediate in the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 109586-43-8. Pack Sizes: 25mg, 250mg. Molecular Formula: C10H9F3O3S, Molecular Weight: 266.24. US Biological Life Sciences.
1, 1, 1-Trifluoromethane sulfonic Acid 2-(2-Propen-1-yl)phenyl Ester-d4 is an isotope labelled intermediate in the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C10H5D4F3O3S, Molecular Weight: 270.26. US Biological Life Sciences.
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1,1,2-Triethoxyethane
1,1,2-Triethoxyethane is an intermediate used to synthesize pyrazolopyrimidine derivatives as COX-2 selective inhibitors. It is also used to prepare [ (1, 2, 4-oxadiazolylphenoxy) alkyl]isoxazoles as antiviral agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 4819-77-6. Pack Sizes: 1g, 5g. Molecular Formula: C8H18O3, Molecular Weight: 162.229999999999. US Biological Life Sciences.
1,1'-Bis(2,6-dichlorophenyl)-[5,5'-biindoline]-2,2'-dione is an intermediate in the synthesis of metabolite of Diclofenac (D436450), which is an nonsteroidal anti-inflammatory compound acting as decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C28H16Cl4N2O2. US Biological Life Sciences.
1-(2,6-Dichloro-4-hydroxphenyl)-1,3-dihydroindol-2-one-13C6 is an intermediate in synthesizing 4-Hydroxy Diclofenac-13C6, a labelled metabolite of Diclofenac, which is a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C813C6H9Cl2NO2. US Biological Life Sciences.
1-(2,6-Dichloro-4-hydroxyphenyl)-1,3-dihydro-2H-Indol-2-one-d4 is an isotope labelled metabolite of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C14H5D4Cl2NO2. US Biological Life Sciences.
1, 3-Bis (methoxymethoxy) -5-[ (1E) -2-[4- (methoxymethoxy) phenyl]ethenyl]-benzene is a useful synthetic intermediate in the synthesis of Resveratrol Impurity B (H950990); an impurity of Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. CAS No. 1414361-09-3. Pack Sizes: 1g, 10g. Molecular Formula: C20H24O6, Molecular Weight: 360.4. US Biological Life Sciences.
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1-(4-Ethoxyphenyl)-3-methyl-4-hexen-1-one
1-(4-Ethoxyphenyl)-3-methyl-4-hexen-1-one is an intermediate in synthesizing Apricoxib (A729850), which is an orally active, selective COX-2 inhibitor, used as as an analgesic and anti-inflammatory agent, and also has anticancer potential, since COX-2 inhibition can reduce tumor growth and augment therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 1337994-12-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H20O2, Molecular Weight: 232.32. US Biological Life Sciences.
An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Synonyms: Etoricoxib YY. Grades: ≥95%. CAS No. 1027162-35-1. Molecular formula: C15H15NO4S. Mole weight: 305.35.
An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Synonyms: 3-[2-(4-(methylthio)phenyl)acetyl](6-methyl)pyridine; Ethanone, 1-(6-ethyl-3-yridinyl)-2-4-(methylthio)henyl]-; Etoricoxib Impurity P. Grades: ≥95%. CAS No. 221615-72-1. Molecular formula: C15H15NOS. Mole weight: 257.35.
1-Bromo-3,5-difluorobenzene
1-Bromo-3,5-difluorobenzene is used in the synthesis of selective antagonists of GluN2C/GluN2D is used in the synthesis of COX-2 inhibitors as anti-inflammatory agents and anti-cancer agents. Group: Biochemicals. Alternative Names: 1,3-Difluoro-5-bromobenzene; 1-Bromo-3,5-difluorobenzene; 3,5-Difluoro-1-bromobenzene; 3,5-Difluorobromobenzene; 3,5-Difluorophenyl Bromide; 5-Bromo-1,3-difluorobenzene. Grades: Highly Purified. CAS No. 461-96-1. Pack Sizes: 25g. US Biological Life Sciences.
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1-Hydroxy-o-carborane
1-Hydroxy-o-carborane is a reactant used in the synthetic preparation of Asborin, which is the carbaborane analog of Aspirin, proved to be an active cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 23987-99-7. Pack Sizes: 10mg, 20mg. Molecular Formula: C2H12B10O, Molecular Weight: 160.229999999999. US Biological Life Sciences.
Worldwide
1-Propyl Etodolac
1-Propyl Etodolac is an impurity in the synthesis of Etodolac (E933100), may have use in the treatment of myeloma. COX-1/COX-2/ β-catenin inhibitors, or anti-inflammatory agent. Group: Biochemicals. Alternative Names: 1-Ethyl-1,3,4,9-tetrahydro-8-(1-methylethyl)-Pyrano[3,4-b]indole-1-acetic Acid. Grades: Highly Purified. CAS No. 57816-83-8. Pack Sizes: 50mg. US Biological Life Sciences.
2-[2- (2, 6-Dichloro-4-hydroxphenylamino) phenyl-d4]-N, N-dimethylacetamide is an intermediate in the synthesis of 4-Hydroxy Diclofenac-d4 (H825227), is an isotope labeled metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1382084-40-3. Pack Sizes: 500ug, 5mg. Molecular Formula: C16H12D4Cl2N2O2, Molecular Weight: 343.24. US Biological Life Sciences.
2- (2- ( (2, 6-Dichloro-4-methoxyphenyl) amino) phenyl-d4) -N, N-dimethylacetamide is the labeled analogue of 2- (2- ( (2, 6-Dichloro-4-methoxyphenyl) amino) phenyl) -N, N-dimethylacetamide which is used in the synthesis of the acyl glucuronide and hydroxy metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1382084-37-8. Pack Sizes: 1mg, 10mg. Molecular Formula: C17H14D4Cl2N2O2, Molecular Weight: 357.27. US Biological Life Sciences.
2- (2- ( (2, 6-Dichloro-4-methoxyphenyl) amino) phenyl) -N, N-dimethylacetamide is used in the synthesis of the acyl glucuronide and hydroxy metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 698357-36-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C17H18Cl2N2O2, Molecular Weight: 353.24. US Biological Life Sciences.
2-?[ (2, ?6-Dichloro-?4-?oxo-?2, ?5-?cyclohexadien-?1-?ylidene) ?amino]?-benzeneacetic Acid is a related compound of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. 2-?[ (2, ?6-Dichloro-?4-?oxo-?2, ?5-?cyclohexadien-?1-?ylidene) ?amino]?-benzeneacetic Acid can be used to study cytochrome P 450 isoforms involved in the bioactivation of diclofenac to reactive p-benzoquinone imines (4). Group: Biochemicals. Grades: Highly Purified. CAS No. 928343-25-3. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H9Cl2NO3, Molecular Weight: 310.13. US Biological Life Sciences.
Worldwide
2-(2,6-Dichlorophenoxy)-N-phenylacetamide
2-(2,6-Dichlorophenoxy)-N-phenylacetamide is a related compound of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 146607-19-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C14H11Cl2NO2. US Biological Life Sciences.
13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: N- (2, 6-Dichlorophenyl) anthranilaldehyde; 2- (2, 6-Dichloroanilino) benzaldehyde; o- (2, 6-Dichloroanilino) benzaldehyde; Diclofenac Aldehyde. Grades: Highly Purified. CAS No. 22121-58-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
2-(2-Iodophenyl-d4)acetic Acid
2-(2-Iodophenyl-d4)acetic Acid is an intermediate in the synthesis of Diclofenac-d4 (D436452), the labeled analogue of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1217360-62-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C8H3D4IO2, Molecular Weight: 266.07. US Biological Life Sciences.
Worldwide
2-(2-Iodophenyl-d4)-N,N-dimethylacetamide
2-(2-Iodophenyl-d4)-N,N-dimethylacetamide is an intermediate in the synthesis of Diclofenac-d4 (D436452), the labeled analogue of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1217360-63-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C10H8D4INO, Molecular Weight: 293.14. US Biological Life Sciences.
Worldwide
2,4,6-trichloro-N-phenylaniline
A Diclofenac impurity which is a non-selective COXinhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Synonyms: 2,4,6-Trichlorodiphenylamine; Diphenylamine, 2,4,6-trichloro; Diclofenac Impurity 10. CAS No. 15362-44-4. Molecular formula: C12H8Cl3N. Mole weight: 272.56.
2-(4-Methanesulfonylphenyl)-1-pyridin-3-ylethanone is an intermediate in synthesizing Desmethyl Etoricoxib (D296895), which is an impurity of Etoricoxib (E934100), a specific inhibitor of COX-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 40061-50-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C14H13NO3S. US Biological Life Sciences.
Worldwide
2,5-Dimethylcelecoxib
2,5-Dimethylcelecoxib is an analogue of celecoxib (HY-14398) with anticancer activity but without COX-2 inhibitory activity. 2,5-Dimethylcelecoxib exerts its anti-cancer cell proliferation effect by inhibiting the core mechanism of the Wnt/β-catenin signaling pathway. 2,5-Dimethylcelecoxib also inhibits T-cell factor-dependent transcriptional activity and inhibits expression of the Wnt/β-catenin target gene products cyclin D1 and survivin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 457639-26-8. Pack Sizes: 1 mg. Product ID: HY-W010995.
2,5-Dimethyl Celecoxib
A non-cyclooxygenase-2 inhibitor analog of Celecoxib. The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib. Group: Biochemicals. Alternative Names: 4-[5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; DMC. Grades: Highly Purified. CAS No. 457639-26-8. Pack Sizes: 25mg. US Biological Life Sciences.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonamide, 2-(5-methyl-3-phenyl-4-isoxazolyl)-; Parecoxib Impurity 48. CAS No. 2304623-35-4. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 37. CAS No. 2304623-37-6. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
2,6-Dichlorodiphenylamine
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COXinhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells. Group: Inhibitors. CAS No. 15307-93-4. Molecular formula: C13H12N2OS. Mole weight: 238.11. Appearance: Solid. Purity: 0.9971. Canonical SMILES: ClC1=C(NC2=CC=CC=C2)C(Cl)=CC=C1. Catalog: ACM15307934.
2,6-Dichlorodiphenylamine
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti- Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COXinhibitor, with IC 50 s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,6-Dichloro-N-phenylaniline. CAS No. 15307-93-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W012126.
An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Synonyms: 6'-methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine; Etoricoxib C; 2,3'-Bipyridine, 6'-methyl-3-[4-(methylsulfonyl)phenyl]-. Grades: ≥95%. CAS No. 1350206-14-2. Molecular formula: C18H16N2O2S. Mole weight: 324.40.
2-Allylphenol
2-Allylphenol is an protected intermediate in the synthesis of metabolites of Diclofenac, a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Heterocyclic organic compoundallyl monomers. Alternative Names: 2-ALLYLPHENOL;ALLYLPHENOL-2;O-ALLYLPHENOL;Phenol, 2-(2-propenyl)-;2-(2-propenyl)-pheno. CAS No. 1745-81-9. Molecular formula: C9H10O. Mole weight: 134.18 g/mol. Appearance: Colorless to Light Yellow to Light Orange Clear Liquid. Purity: 98.0%(GC). IUPACName: 2-prop-2-enylphenol. Canonical SMILES: C=CCC1=CC=CC=C1O. Density: 1.02. ECNumber: 217-119-0. Catalog: ACM-MO-1745819.
2-Allylphenol
2-Allylphenol is an protected intermediate in the synthesis of metabolites of Diclofenac, a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Monomers. Alternative Names: 2-ALLYLPHENOL; ALLYLPHENOL-2; O-ALLYLPHENOL; Phenol, 2-(2-propenyl)-; 2-(2-propenyl)-pheno. CAS No. 1745-81-9. Product ID: 2-prop-2-enylphenol. Molecular formula: 134.18. Mole weight: C9H10O. C=CCC1=CC=CC=C1O. InChI=1S/C9H10O/c1-2-5-8-6-3-4-7-9 (8)10/h2-4, 6-7, 10H, 1, 5H2. QIRNGVVZBINFMX-UHFFFAOYSA-N. 98%+.
2-Allylphenol-d4
2-Allylphenol-d4 is an protected intermediate in the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C9H6D4O, Molecular Weight: 138.199999999999. US Biological Life Sciences.
Worldwide
2-Bromo-6-methoxynaphthalene
A metabolite of Naproxen, which is a non-selective COXinhibitor. Synonyms: Naphthalene, 2-bromo-6-methoxy-; 2-Methoxy-6-bromonaphthalene; 6-Bromo-2-methoxynaphthalene; 6-Methoxy-2-bromonaphthalene; 6-Methoxynaphth-2-yl bromide; NSC 3236; Naproxen Impurity N; Naproxen EP Impurity N. Grades: ≥95%. CAS No. 5111-65-9. Molecular formula: C11H9BrO. Mole weight: 237.09.
2-(Bromoacetyl)-6-methoxynaphthalene
2-(Bromoacetyl)-6-methoxynaphthalene is used in the preparation of 2-(2-arylmorpholino)ethyl esters of ibuprofen hydrochlorides as COX-2 and serotonin reuptake inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 10262-65-4. Pack Sizes: 100mg, 1g. Molecular Formula: C13H11BrO2, Molecular Weight: 279.13. US Biological Life Sciences.
Worldwide
2-Chloro-3-(phenylamino)-2-propenal
2-Chloro-3-(phenylamino)-2-propenal is an intermediate in the synthesis of 3-Amino-2-chloro-propenal (A604190). 3-Amino-2-chloro-propenal is a chemical reagent in the synthesis of a COX-2 specific inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 131139-84-9. Pack Sizes: 1g, 2.5g. Molecular Formula: C9H8ClNO, Molecular Weight: 181.62. US Biological Life Sciences.
2-Chloro-N-(2,6-dichloro-4-methoxyphenyl)-N-phenylacetamide is an intermediate in the synthesis of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 136099-58-6. Pack Sizes: 10mg. US Biological Life Sciences.
2-Hydroxyphenylacetic Acid-d4 Trifluoromethane sulfonate is an protected intermediate in the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C9H3D4F3O5S. US Biological Life Sciences.
2-Hydroxyphenylacetic Acid Trifluoromethane sulfonate is an protected intermediate in the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H7F3O5S, Molecular Weight: 284.209999999999. US Biological Life Sciences.
Worldwide
2-Methoxyacetic Acid-d3
Isotope labelled analogue of 2-Methoxyacetic Acid, a synthetic intermediate in the synthesis of dimethyl (alkyloxy) [ (methylsulfonyl) phenyl]furanones as COX-2 inhibitors. Group: Biochemicals. Alternative Names: 2-Methoxyacetic Acid-d3; Methoxyacetic Acid-d3; Methoxyethanoic Acid-d3; NSC 7300-d3; Methoxyacetic Acid-d3. Grades: Highly Purified. CAS No. 345910-00-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
2-Methoxynaphthalene
A metabolite of Naproxen, which is a non-selective COXinhibitor. Synonyms: Naphthalene, 2-methoxy-; 2-Naphthol methyl ether; 2-Naphthyl methyl ether; 6-Methoxy-2-naphthalene; Methyl 2-naphthyl ether; Methyl β-naphthyl ether; Nerolin; Nerolin (old); Nerolin yara yara; NSC 4171; Yara yara; β-Methoxynaphthalene; β-Naphthol methyl ether; β-Naphthyl methyl ether. Grades: ≥95%. CAS No. 93-04-9. Molecular formula: C11H10O. Mole weight: 158.20.
Used in the preparation of DFP analog as potent COX-2 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 516453-68-2. Pack Sizes: 10mg. US Biological Life Sciences.
2-Methyl-5- (3- (4- (methylsulfonyl) phenyl) furan-2-yl) pyridine is a byproduct from the preparation of methyl sulfonyl phenyl bipyridine, a COX-2 specific inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 307531-96-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C17H15NO3S, Molecular Weight: 313.37. US Biological Life Sciences.
Worldwide
2-Methyl-Celecoxib
2-Methyl-Celecoxib is an analog of the anti-inflammatory drug Celecoxib (C251000). Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 170570-09-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H16F3N3O2S, Molecular Weight: 395.4. US Biological Life Sciences.
Worldwide
2-Methylcoumaran
2-Methylcoumaran is an impurity formed during the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1746-11-8. Pack Sizes: 500mg, 2.5g. Molecular Formula: C9H10O, Molecular Weight: 134.18. US Biological Life Sciences.
Worldwide
2-Nitrodiphenyl Sulfide
An impurity of Nimesulide, which is a selective COX-4 inhibitor. Synonyms: 2-Nitrophenyl Phenyl Sulfide; 1-Nitro-2-(phenylthio)benzene; 2-Nitrodiphenyl Sulfide. Grades: > 95%. CAS No. 4171-83-9. Molecular formula: C12H9NO2S. Mole weight: 231.28.
2-Phenoxyaniline
An impurity of Nimesulide, which is a selective COX-2 inhibitor. Synonyms: 2-phenoxyaniline. Grades: 99 %. CAS No. 2688-84-8. Molecular formula: C12H11NO. Mole weight: 185.22.
2-Phenylthio-5-propionylphenylacetic Acid
2-Phenylthio-5-propionylphenylacetic Acid is a useful synthetic intermediate in the synthesis of Zaltoprofen (Z146000); an inhibitor of Cox-1 and Cox-2. Zaltoprofen preferentially inhibits Cox-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 103918-73-6. Pack Sizes: 1g, 10g. Molecular Formula: C17H16O3S. US Biological Life Sciences.
3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol is the impurity C of Resveratrol (R150000); a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. CAS No. 678149-02-5. Pack Sizes: 5mg, 50mg. Molecular Formula: C21H18O3, Molecular Weight: 318.37. US Biological Life Sciences.
3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol-d7 is the isotope labelled analog of 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol (H950995); the impurity C of Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C21H11D7O3, Molecular Weight: 325.41. US Biological Life Sciences.
3-[[3-fluoro-5- (tetrahydro-4-methoxy-2H-pyran-4-yl) phenoxy]methyl]-1-[4- (methylsulfonyl) phenyl]-5-phenyl-1H-pyrazole is a dual inhibitor of Cox-2 and 5-LO. Group: Biochemicals. Grades: Highly Purified. CAS No. 443919-96-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C29H29FN2O5S, Molecular Weight: 536.61. US Biological Life Sciences.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 09. CAS No. 386273-25-2. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
3-(7-Ethyl-1H-indol-3-yl)-3-(7-ethyl-3-(2-Hydroxyethyl)-1H-indol-2-yl)Pentanoic Acid is an impurity in the synthesis of Etodolac (E933100). Like other Etodolac impurities (P835255) may have use in the treatment of myeloma. COX-1/COX-2/ β-catenin inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C27H32N2O3, Molecular Weight: 432.55. US Biological Life Sciences.
Worldwide
3-Amino-2-chloro-propenal
3-Amino-2-chloro-propenal is a chemical reagent in the synthesis of a COX-2 specific inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 221615-73-2. Pack Sizes: 10mg, 100mg. Molecular Formula: C3H4ClNO. US Biological Life Sciences.
Worldwide
3-methyl-4,5-diphenylisoxazole
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 38. CAS No. 75115-00-3. Molecular formula: C16H13NO. Mole weight: 235.28.
3-(N-Acetyl-L-cystein-S-yl) Acetaminophen
3-(N-Acetyl-L-cystein-S-yl) Acetaminophen is a metabolite of Acetaminophen, which is a selective COX-2 inhibitor used as an antipyretic, analgesic, and anti-inflammatory agent. Synonyms: N-Acetyl-S-[5-(acetylamino)-2-hydroxyphenyl]-L-Cysteine; PCM-M; 3-[(5-Acetamido-2-Hydroxyphenyl)thio]-N-Acetylalanine; Acetaminophen Mercapturate; N-Acetyl-2-(N-Acetyl-L-Cysteinyl)-4-Aminophenol; S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine; Acetaminophen-2-mercapturate. Grades: 96%. CAS No. 52372-86-8. Molecular formula: C13H16N2O5S. Mole weight: 312.34.
3-O-Methylquercetin
3-O-Methylquercetin is an inhibitor of cAMP and CGMP-phosphodiesterase ( PDE ) with IC 50 at 13.8 μM and 14.3 μM, respectively. 3-O-Methylquercetin is an inhibitor of β-secretase with an IC 50 of 6.5 μM. 3-O-Methylquercetin has a neuroprotective effect against neuronal death caused by oxidative damage. 3-O-Methylquercetin has strong antiviral activity against poliovirus, coxsackie virus and human rhinovirus. 3-O-Methylquercetin has anti-inflammatory and trachea-relaxing effects and can be used in the study of inflammatory diseases and asthma [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 1486-70-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1860.
4-[3-(Acryloyloxy)propoxy]benzoic acid
4-[3-(Acryloyloxy)propoxy]benzoic acid, an essential raw material in the synthesis of pharmaceuticals and agrochemicals, possesses enormous potential as a COX-2 inhibitor, thereby providing considerable therapeutic benefits in alleviating inflammation and pain. Moreover, it serves as an indispensable reagent in organic chemistry and is exclusively utilized in the synthesis of polymeric compounds and surface functionalization. Its multifaceted applications in various fields highlight its enormous industrial significance. Synonyms: 4-[3-[(1-Oxo-2-propen-1-yl)oxy]propoxy]benzoic acid. CAS No. 245349-46-6. Molecular formula: C13H14O5. Mole weight: 250.25.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 39; Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)-. Grades: 98%. CAS No. 181695-84-1. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 15; Valdecoxib Impurity 13. CAS No. 2251048-58-3. Molecular formula: C16H15N3O5S2. Mole weight: 393.43.
4-(4-chlorophenyl)-5-methyl-3-phenylisoxazole
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 40. CAS No. 1448355-87-0. Molecular formula: C16H12ClNO. Mole weight: 269.72.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 29. CAS No. 2338845-31-9. Molecular formula: C32H24N2O4S. Mole weight: 532.61.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 47. Grades: >95%. CAS No. 2242749-01-3. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
4-Hydrazino Benzene sulfonic Acid
Hemihydrate of 4-Hydrazino Benzene sulfonic Acid is used in analytical experiments to determine trace components of mixtures. Also used in the synthesis of inhibitors of coxsackievirus B3 replication. Tartrazine (T007700) analog. Group: Biochemicals. Alternative Names: p-Hydrazino Benzene sulfonic Acid; 4-Sulfophenylhydrazine; NSC 1608; Phenylhydrazine-4-sulfonic Acid; Phenylhydrazine-p-sulfonic Acid; Sulfanilic Acid Hydrazine; p-Hydrazino Benzene sulfonic Acid; p- hydrazinophenyl sulfonic Acid; p-Sulfophenylhydrazine. Grades: Highly Purified. CAS No. 98-71-5. Pack Sizes: 50g. US Biological Life Sciences.
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