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| Product | Description | |
|---|---|---|
| cyclin-dependent kinase | Activation of cyclin-dependent kinases requires association of the enzyme with a regulatory subunit referred to as a cyclin. It is the sequential activation and inactivation of cyclin-dependent kinases, through the periodic synthesis and destruction of cyclins, that provides the primary means of cell-cycle regulation. Group: Enzymes. Synonyms: Bur1; Bur1 Cdk; Cak1; Cak1p; cdc2; cdc2 kinase; Cdc28p; CDK; cdk-activating kinase; Cdk-activating protein kinase; cdk1; cdk2; Cdk2; cdk3; cdk4; cdk5; cdk6; cdk7; cdk8; cdk9; cyclin A-activated cdc2; cyclin A-activated cdk2; cyclin D-cdk6 kinase; cyclin D-depende. Enzyme Commission Number: EC 2.7.11.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3142; cyclin-dependent kinase; EC 2.7.11.22; Bur1; Bur1 Cdk; Cak1; Cak1p; cdc2; cdc2 kinase; Cdc28p; CDK; cdk-activating kinase; Cdk-activating protein kinase; cdk1; cdk2; Cdk2; cdk3; cdk4; cdk5; cdk6; cdk7; cdk8; cdk9; cyclin A-activated cdc2; cyclin A-activated cdk2; cyclin D-cdk6 kinase; cyclin D-dependent kinase; cyclin E kinase; cyclin-A associated kinase; cyclin-dependent kinase 6; cyclin-dependent kinase-2; cyclin-dependent kinase-4; cyclin-dependent protein kinase activating kinase; cyk; D-type cyclin kinase; nclk; neuronal cdc2-like kinase; PCTAIRE-1; STK25. Cat No: EXWM-3142. |  |
| Cyclin-dependent kinase 4 (924-932) | Cyclin-dependent kinase 4 (924-932) is a truncated fragment of Cyclin-dependent kinase 4. This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Synonyms: cell division protein kinase 4 (924-932). |  |
| 10Z-Hymenialdisine | Insecticidal and cytotoxic. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1). Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor. MARK (microtubule affinity-regulating kinase) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C??H??BrN?O?, Method for Determining. US Biological Life Sciences. |  Worldwide |
| 10Z-Hymenialdisine (Hymenialdisine, 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one) | Isolated from sponge Axinella carteri. A potent inhibitor of mitogen-activated protein kinase kinase-1 (MEK-1) (IC50=6nm). Blocks the in vivo phosphorylation of the microtubule-binding protein tau at sites that are hyperphosphorylated by glycogen synthase kinase-b (GSK-3b) and CDK5/p35 in Alzheimers disease. Inhibitor of DNA damage checkpoint at G2 phase (IC50=6uM), cyclin-dependent kinases CDK1/cyclin B (IC50=22nm), CDK2/cyclin A (IC50=70 nm), CDK2/cyclin E (IC50=40nm), CDK4/cyclin D1 (IC50 = 600nm), CDK5/p25 (IC50=28nm), GSK-3b (IC50=10nm), and casein kinase 1 (CK1) (IC50=35nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| 1-(2,3,5-Tri-O-benzoyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one | 1-(2,3,5-Tri-O-benzoyl-b-D-ribofuranosyl)-5-Nitropyridine-2(1H)-One, a cyclin-dependent kinase 9 (CDK9) inhibitor, has exhibited a compelling potential against malignancies such as breast cancer, prostate cancer and multiple myeloma. It interferes with the propagation and fission of cancer-bearing cells, ultimately restraining the pathogenesis of the malady. This product has shown noteworthy efficacy in the discovery and evolution of progressive anti-tumor therapies whilst facilitating CDK9 inhibition`s related research undertakings. Synonyms: 5-nitro-1-(2',3',5'-tri-O-benzoyl-beta-ribofuranosyl)-2-pyridone; 5-nitro-1-(2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)-2-pyridone; (2R,3R,4R,5R)-2-((Benzoyloxy)methyl)-5-(5-nitro-2-oxopyridin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate; 2(1H)-Pyridinone, 5-nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-. Grade: ≥95%. CAS No. 59892-37-4. Molecular formula: C31H24N2O10. Mole weight: 584.53. | |
| 1- (3-Nitrophenyl) methanesulfonamide | 1- (3-Nitrophenyl) methanesulfonamide is a useful synthetic intermediate. It can be used to synthesize synthesize disubstituted pyridine derivatives as inhibitors of the protein cyclin-dependent kinase (CDK). Group: Biochemicals. Grades: Highly Purified. CAS No. 110654-66-5. Pack Sizes: 500mg, 5g. Molecular Formula: C7H8N2O4S, Molecular Weight: 216.21. US Biological Life Sciences. | Worldwide |
| 1,4-Bis(4-nitrophenyl)piperazine | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1,4-Bis(4-nitrophenyl)piperazine; 16264-05-4; Piperazine, 1,4-bis(4-nitrophenyl)-EINECS 240-371-8UNII-P6TE7B2EYY. CAS No. 16264-05-4. Molecular formula: C16H16N4O4. Mole weight: 328.328. | |
| 1-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-1-oxidopyridin-3-yl)piperazine 1-oxide | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib Impurity 25. Grade: >95%. CAS No. 2488840-59-9. Molecular formula: C24H29N7O4. Mole weight: 479.54. | |
| 1-?(6-?Nitro-?3-?pyridinyl)?piperazine | 1-?(6-?Nitro-?3-?pyridinyl)?piperazine is a reagent used in the preparation of highly potent and orally bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine cyclin-dependant kinases as anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Group: Biochemicals. Grades: Highly Purified. CAS No. 775288-71-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H12N4O2. US Biological Life Sciences. | Worldwide |
| 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid | 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid is a reagent used in the synthesis of cyclin-dependent kinase 4-inhibitors (CDK4) for cancer treatments. Also used towards the discovery of a potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer pased upon benzimidazole carboxamide moieties. Group: Biochemicals. Grades: Highly Purified. CAS No. 188527-21-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H15NO4, Molecular Weight: 249.26. US Biological Life Sciences. | Worldwide |
| 1-Boc-4-(6-aminopyridin-3-yl)piperazine | 1-Boc-4-(6-aminopyridin-3-yl)piperazine is used to prepare pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of cyclin-dependent kinases 4 and 6. Group: Biochemicals. Grades: Highly Purified. CAS No. 571188-59-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H22N4O2. US Biological Life Sciences. | Worldwide |
| 1-Boc-4-(6-aminopyridin-3-yl)piperazine-d4 | 1-Boc-4-(6-aminopyridin-3-yl)piperazine-d4 is an intermediate in synthesizing Palbociclib-d4 (P139901), an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Group: Biochemicals. Grades: Highly Purified. CAS No. 1808106-94-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C14H18D4N4O2. US Biological Life Sciences. | Worldwide |
| 1-Piperazin-N-oxide Palbociclib | 1-Piperazin-N-oxide Palbociclib is a derivative compound of Palbociclib (P139900). Palbociclib (also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H29N7O3, Molecular Weight: 463.53. US Biological Life Sciences. | Worldwide |
| 2,6-Dichloro-9-isopropylpurine | Bohemine cyclin-dependent kinase inhibitor for the treatment of leukemia or other cancer. Group: Biochemicals. Alternative Names: 2,6-Dichloro-9-(1-methylethyl)-9H-purine. Grades: Highly Purified. CAS No. 203436-45-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2-? Chloro-? 8-? cyclopentyl-? 5-? methyl-? 8H-? pyrido [2, ? 3-? d] ? pyrimidin-? 7-? one | 2-? Chloro-? 8-? cyclopentyl-? 5-? methyl-? 8H-? pyrido [2, ? 3-? d] ? pyrimidin-? 7-? one is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Group: Biochemicals. Grades: Highly Purified. CAS No. 1013916-37-4. Pack Sizes: 250mg, 1g. Molecular Formula: C13H14ClN3O, Molecular Weight: 263.72. US Biological Life Sciences. | Worldwide |
| 2-Chloro-9-methyl-6-(benzylamino)purine | 2-Chloro-9-methyl-6-(benzylamino)purine is an intermediate in the synthesis of Olomoucine (O567000), a purine derivative which inhibits cyclin-dependent kinases and induces G1 arrest. Group: Biochemicals. Grades: Highly Purified. CAS No. 101622-53-1. Pack Sizes: 25mg, 250mg. Molecular Formula: C13H12ClN5. US Biological Life Sciences. | Worldwide |
| 2-Chloro-9-methyl-6-(benzylamino)purine-d3 | 2-Chloro-9-methyl-6-(benzylamino)purine-d3 is an isotope labelled intermediate in the synthesis of Olomoucine (O567000), a purine derivative which inhibits cyclin-dependent kinases and induces G1 arrest. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C13H9D3ClN5. US Biological Life Sciences. | Worldwide |
| 2-Chloro-N-(phenylmethyl)-1H-purin-6-amine | 2-Chloro-N-(phenylmethyl)-1H-purin-6-amine is an intermediate in the synthesis of Olomoucine (O567000), a purine derivative which inhibits cyclin-dependent kinases and induces G1 arrest. Group: Biochemicals. Grades: Highly Purified. CAS No. 39639-47-9. Pack Sizes: 100mg, 1g. Molecular Formula: C12H10ClN5. US Biological Life Sciences. | Worldwide |
| 2-Iodoanisole | 2-Iodoanisole is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 529-28-2. Pack Sizes: 10g, 25g. Molecular Formula: C7H7IO, Molecular Weight: 234.03. US Biological Life Sciences. | Worldwide |
| (2R,4aR,7R,8S,8aS)-7-(2-Amino-6-chloro-9H-purin-9-yl)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-ol | (2R,4aR,7R,8S,8aS)-7-(2-Amino-6-chloro-9H-purin-9-yl)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-ol, a potentially efficacious cancer therapeutic agent, remarkably impedes cyclin-dependent kinase 4/6 (CDK4/6) that are of paramount importance for the progress of cell cycle, thus exhibiting promising therapeutic potential for the remission of breast cancer as well as other types of malignancies. It has been extensively investigated that obstructing CDK4/6 activities effectively decelerates the malignant proliferation of cancerous cells which substantiates the validation of this therapeutic candidate. Synonyms: 2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol. CAS No. 705967-79-9. Molecular formula: C18H18ClN5O4. Mole weight: 403.82. | |
| 3-Amino- Benzene methanesulfonamide | 3-Amino- Benzene methanesulfonamide can be used to synthesize disubstituted pyridine derivatives as inhibitors of the protein cyclin-dependent kinase (CDK). Group: Biochemicals. Grades: Highly Purified. CAS No. 344750-15-8. Pack Sizes: 250mg, 2.5g. Molecular Formula: C7H10N2O2S, Molecular Weight: 186.23. US Biological Life Sciences. | Worldwide |
| 3-ATA | 3-ATA is a selective cyclin-dependent kinase 4 (CDK4) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 129821-08-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C13H10N2OS, Molecular Weight: 242.3. US Biological Life Sciences. | Worldwide |
| 3-Methylthienyl-carbonyl-JNJ-7706621 | 3-Methylthienyl-carbonyl-JNJ-7706621 is a potent and selective cyclin-dependent kinase (CDK) inhibitor, with IC50s of 6.4 nM and 2 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. It also has strong inhibitory effect on GSK-3 (IC50 = 0.041 μM) and modest potency against CDK4, VEGF-R2 and FGF-R2 with IC50s of 0.11, 0.13 and 0.22 μM, respectively. It can be used in cancer research. Synonyms: 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f; 4-({5-amino-1-[(3-methylthiophen-2-yl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzene-1-sulfonamide. CAS No. 443798-09-2. Molecular formula: C14H14N6O3S2. Mole weight: 378.43. | |
| 5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine; 1823404-28-9; CS-0011349; D87404; 5-?Bromo-?4-?chloro-?N-?cyclopentylpyrimidin?-?2-?amine. CAS No. 1823404-28-9. Molecular formula: C9H11BrClN3. Mole weight: 276.56. | |
| 6-acetyl-2-amino-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib Impurity 27; Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-2-amino-8-cyclopentyl-5-methyl-. CAS No. 571189-64-5. Molecular formula: C15H18N4O2. Mole weight: 286.33. | |
| 6-Bromo-8-cyclopentyl-2-[[5-(4-Boc-1-piperazinyl)-2-pyridyl]amino]-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 4-[6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxo-2-pyrido[2,3-d]pyrimidinyl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester; tert-butyl 4-[6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylate. CAS No. 571188-82-4. Molecular formula: C27H34BrN7O3. Mole weight: 584.51. | |
| 6-Bromotubercidin | 6-Bromotubercidin, a formidable suppressor of cyclin-dependent kinases (CDKs) and adenosine kinase, extends its utility within the research of afflictions ranging from cancerous maladies, inflammatory agonies to neurophysiological perturbations. Synonyms: 8-Bromo-7-deazaadenosine; 6-Br-Tu; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-bromo-7-beta-D-ribofuranosyl-. CAS No. 78000-56-3. Molecular formula: C11H13BrN4O4. Mole weight: 345.15. | |
| 6-Desacetyl-6-Bromo Palbociclib | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 6-Bromo-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one; Pyrido-[2,3-d]-pyrimidin-7-one 41. CAS No. 851067-56-6. Molecular formula: C22H26BrN7O. Mole weight: 484.402. | |
| 6-Desacetyl-6-Bromo Palbociclib Hydrochloride | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 6-bromo-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride. CAS No. 850918-83-1. Molecular formula: C22H27ClBrN7O. Mole weight: 520.86. | |
| 6-Desacetyl Palbociclib | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-; Pyrido-[2,3-d]-pyrimidin-7-one 38. CAS No. 571190-22-2. Molecular formula: C22H27N7O. Mole weight: 405.506. | |
| 6-Desacetyl Palbociclib Hydrochloride | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride. CAS No. 571189-66-7. Molecular formula: C22H28ClN7O. Mole weight: 441.96. | |
| 7-BIO | 7-BIO is a derivative of indirubin that triggers a rapid cell death process that is distinct from apoptosis and devoid of cytochrome c release or caspase activation. Furthermore, in contrast to other indirubin derivatives, 7-BIO has only marginal activity against the classic indirubin targets, cyclin-dependent kinases and GSK3. Synonyms: 7-Bromoindirubin-3'-oxime; 7-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol. Grade: ≥99%. CAS No. 916440-85-2. Molecular formula: C16H10BrN3O2. Mole weight: 356.2. | |
| 8-cyclopentyl-5-methyl-2,6-bis((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-5-methyl-2,6-bis[[5-(1-piperazinyl)-2-pyridinyl]amino]; Palbociclib Impurity G. CAS No. 2458234-37-0. Molecular formula: C31H39N11O. Mole weight: 581.73. | |
| Abemaciclib | Abemaciclib is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 1231929-97-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C27H32F2N8, Molecular Weight: 506.59. US Biological Life Sciences. | Worldwide |
| Abemaciclib | Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: LY-2835219; LY 2835219; LY2835219; Verzenio; N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine. Grade: ≥98%. CAS No. 1231929-97-7. Molecular formula: C27H32F2N8. Mole weight: 506.61. | |
| Abemaciclib-[13C4,15N2] | Abemaciclib-[13C4,15N2] is a labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-ethylpiperazin-1-yl-2,3,5,6-13C4-1,4-15N2)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-[13C4,15N2]. Grade: ≥99% atom 13C; ≥98% atom 15N. Molecular formula: C23[13C]4H32F2N6[15N]2. Mole weight: 512.56. | |
| Abemaciclib-[d10] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-(methyl-d3)-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-(methyl-d3)-1-[1-(methyl-d3)ethyl-1,2,2,2-d4]-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY-2835219-d10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d10. Grade: >95%. CAS No. 2088650-71-7. Molecular formula: C27H22D10F2N8. Mole weight: 516.66. | |
| Abemaciclib-[d5] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d5; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d5. Grade: > 98%. CAS No. 1809251-51-1. Molecular formula: C27H27D5F2N8. Mole weight: 511.62. | |
| Abemaciclib-[d7] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d7. Grade: > 98%. Molecular formula: C27H25D7F2N8. Mole weight: 513.64. | |
| Abemaciclib-[d8] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-Ethylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D8; [d8]-Abemaciclib; [d8]-LY-2835219; LY-2835219-d8. Grade: ≥90%. CAS No. 2088650-53-5. Molecular formula: C27H24D8F2N8. Mole weight: 514.65. | |
| Abemaciclib Impurity 1-[d12] | Abemaciclib Impurity 1-[d12] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1h-benzo[d]imidazole-D12. Grade: > 98%. Molecular formula: C11D12BrFN2. Mole weight: 283.20. | |
| Abemaciclib Impurity 1-[d5] | Abemaciclib Impurity 1-[d5] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1h-benzo[d]imidazole-d5. Grade: > 98%. Molecular formula: C11H7D5BrFN2. Mole weight: 276.16. | |
| Abemaciclib Impurity 5-[d5] | Abemaciclib Impurity 5-[d5] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: 1-[(6-bromopyridin-3-yl)methyl]-4-ethylpiperazine-d5. Grade: > 98%. CAS No. 1809251-58-8. Molecular formula: C12H13D5BrN3. Mole weight: 289.23. | |
| AG-012917 | AG-012917 is a broad spectrum cyclin-dependent kinase inhibitor with potential anticancer activity. Synonyms: AG 012917; AG012917; (S)-4-((4-amino-5-(2,6-difluorobenzoyl)thiazol-2-yl)amino)-N-((1-methylpyrrolidin-2-yl)methyl)benzamide. Grade: >98%. CAS No. 486414-16-8. Molecular formula: C23H23F2N5O2S. Mole weight: 471.52. | |
| AG-012986 | AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition,>83.1%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hypophosphorylation, cell cycle arrest, decreased Ki-67 tumor staining, and apoptosis in conjunction with antitumor activity. Synonyms: AG 012986; AG012986; Benzamide, 4-((4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl)amino)-N-((1R)-2-(dimethylamino)-1-methylethyl)-. Grade: >98%. CAS No. 486414-35-1. Molecular formula: C22H23F2N5O2S. Mole weight: 459.51. | |
| AG-024104 | AG-024104 is a broad spectrum cyclin-dependent kinase inhibitor with potential anticancer activity. Synonyms: AG 024104; AG024104. Grade: >98%. CAS No. 750575-23-6. Molecular formula: C24H28F2N6O4S2. Mole weight: 566.64. | |
| Alsterpaullone | Alsterpaullone is a potent glycogen synthase kinase-3 inhibitor and a potential therapeutic agent for the treatment of Parkinson disease. Alsterpaullone is also known as 9-Nitropaullone and NSC 705701, which is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Alsterpaullone induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Alsterpaullone is a derivative of kenpaullone with slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Synonyms: 9-Nitropaullone; NSC 705701; 7,12-Dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one. Grade: ≥98%. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.3. | |
| Alvocidib | Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. Uses: For research used only. Synonyms: Flavopiridol; HMR 1275. HMR1275. HMR-1275. Grade: 0.98. CAS No. 146426-40-6. Molecular formula: C21H20ClNO5. Mole weight: 401.84. | |
| Aminopurvalanol A | Aminopurvalanol A is a selective, cell-permeable, reversible and ATP-competitive cyclin-dependent kinase (CDK) inhibitor. It is a 2,6,9-trisubstituted purine analog that displays anti-mitotic as well as anti-tumor properties. It induces cell differentiation by preferentially targeting the G2/M-phase and acts intracellularly by inhibiting both Cdks and MAPKs. It potently inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk5/p35 with IC50s values of 33, 33, 28, and 20 nM, respectively. It also inhibits growth of ovarian leukemic (SR), (IGROV1), colonic (KM12) and lung (NCI-H522) cells in antiproliferative assays in vitro. Synonyms: (2R)-2-[[6-[(3-Amino-5-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol; NG-97; NG97; NG 97; Aminopurvalanol A; Aminopurvalanol-A. Grade: ≥98% by HPLC. CAS No. 220792-57-4. Molecular formula: C19H26ClN7O. Mole weight: 403.91. | |
| Aminopurvalanol A (NG97, (2R)-2-[[6-[(3-Amino-5-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol) | A cell-permeable, reversible and competitive inhibitor of cyclin-dependent kinases. IC50 values are: CDK1/cyclin B (33nm), CDK2/cyclin A (33nm), CDK2/cyclin E (28nm) and CDK5/p35 (20nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 220792-57-4. Pack Sizes: 1mg, 5mg . US Biological Life Sciences. | Worldwide |
| amsilarotene | Amsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. Synonyms: TAC-101; TAC 101; TAC101; Am 555S; Benzoic acid, 4-[[3,5-bis(trimethylsilyl)benzoyl]amino]-. Grade: 99%. CAS No. 125973-56-0. Molecular formula: C20H27NO3Si2. Mole weight: 385.61. | |
| Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01) | Isolated from Streptomyces sp., Antibiotic UCN-01 inhibits protein kinase C (PKC) and cyclin-dependent kinase 2 (CDK2) resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by these anti-cancer agents. Group: Biochemicals. Alternative Names: 7-Hydroxystaurosporine, UCN-01. Grades: Highly Purified. CAS No. 112953-11-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Arcyriaflavin A | Arcyriaflavin A is a potent dual target agent of calcium/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 4 (CDK4). Its IC50 values are 140 nM and 25 nM for CDK4 and CaMKII respectively, which is selective over protein kinase A (PKA) and PKC in vitro. It inhibits proliferation of HCT116 and NCI H460 human carcinoma cells and replication of human cytomegalovirus (HCMV) in vitro. It also inhibits proliferation and induces apoptosis of endometriotic cyst stromal cells (ECSCs). Synonyms: Arcyriaflavin A; Arcyriaflavin-A; 12,13-Dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione; 6,7,12,13-Tetrahydro-5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; Maleimide Indolocarbazole. Grade: ≥98% by HPLC. CAS No. 118458-54-1. Molecular formula: C20H11N3O2. Mole weight: 325.32. | |
| AS2863619 | AS2863619 enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2241300-51-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126675A. |  |
| AS2863619 | AS2863619 is an orally active cyclin-dependent kinase CDK8/19 inhibitor with IC50 of 0.61 nM and 4.277 nM, respectively. In vitro, AS2863619 is a potent Foxp3 inducer in Tconv cells. Synonyms: 4-[1-(2-methyl-1H-benzimidazol-6-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine dihydrochloride; 4-(1-(2-Methyl-1H-benzo[d]imidazol-6-yl)-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine dihydrochloride. CAS No. 2241300-51-4. Molecular formula: C16H14Cl2N8O. Mole weight: 405.24. | |
| Avotaciclib | Avotaciclib (BEY1107) is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BEY1107. CAS No. 1983983-41-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137432. | |
| AZD5438 | AZD5438 is a potent inhibitor of cyclin-dependent kinase (cdk) 1, 2, and 9 (IC(50), 16, 6, and 20 nmol/L, respectively). Broad cdk inhibition may provide an effective method to impair the dysregulated cell cycle that drives tumorigenesis and AZD5438 has the pharmacologic profile that provides an ideal probe to test this premise. Synonyms: AZD5438; AZD-5438; AZD 5438. Grade: 0.98. CAS No. 602306-29-6. Molecular formula: C18H21N5O2S. Mole weight: 371.45664. | |
| Bisindolylmaleimide X hydrochloride | Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIM-X hydrochloride; Ro31-8425 hydrochloride. CAS No. 145317-11-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-108136A. | |
| Bml-259 | BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 267654-00-2. Molecular formula: C14H16N2OS. Mole weight: 260.4. Purity: >98%. IUPACName: 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide. Canonical SMILES: O=C(NC1=NC=C(C(C)C)S1)CC2=CC=CC=C2. Product ID: ACM267654002. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BMS-265246 | BMS-265246 is a potent and selective cyclin-dependent kinase CDK1 and CDK2 inhibitor, with IC50 values of 6 and 9 nM, respectively. BMS-265246 inhibits CHI3L1 (chitinase 3-like-1) stimulation of ACE2 (angiotensin converting enzyme 2) and SPP (viral spike protein priming proteases). BMS-265246 can be used for ovarian cancer and COVID-19 research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 582315-72-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15275. | |
| Bohemine | Bohemine, structurally similar to Olomoucine and Roscovitine, is a 2,6,9-trisubstituted purine derivative that inhibits cyclin-dependent kinases (CDKs) and exhibits anticancer activity. Synonyms: 3-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]propan-1-ol; 6-benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine; bohemine. Grade: ≥97%. CAS No. 189232-42-6. Molecular formula: C18H24N6O. Mole weight: 340.42. | |
| Borrelidin (Treponemycin, U 78548, C2989) | Macrolide antibiotic. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50=0.8nM). Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Blocks the formation of spontaneous lung metastases of B16-BL6 melanoma cells. Cyclin-dependent kinase (CDK) inhibitor. Antiviral. Antimalarial. Group: Biochemicals. Grades: Highly Purified. CAS No. 7184-60-3. Pack Sizes: 500ug, 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| BUR1 | BUR1 is a cyclin-dependent kinase (CDK) of saccharomyces cerevisiae that is homologous to mammalian CDK9 and plays a role in transcriptional elongation. Synonyms: 1-Phenyl-4-(piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 1-phenyl-4-(1-piperidinyl)-; 1-Phenyl-4-(1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 1-phenyl-4-piperidino-; 1-[1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine; BMP upregulator 1; BUR-1; BUR 1; BMP upregulator-1. Grade: ≥95%. CAS No. 23000-46-6. Molecular formula: C16H17N5. Mole weight: 279.34. | |
| Butyrolactone I | Butyrolactone I is an exogenous inhibitor of CDK cyclin-dependent kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 87414-49-1. Pack Sizes: 200ug, 400ug. Molecular Formula: C24H24O7, Molecular Weight: 424.44. US Biological Life Sciences. | Worldwide |
| Butyrolactone I | It is one of a family of three butyrolactones isolated from aspergillus fumigatus. It exhibits antitumor activity and inhibits the cell cycle at the G1/S and G2/M transitions. It is a selective inhibitor of cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Synonyms: Olomoucin; 4'-O-Demethylversicolactone D; (2R)-2,5-Dihydro-4-hydroxy-2-[[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxo-2-furancarboxylic Acid Methyl Ester; (+)-3''-Dimethylallyl-butyrolactone II. Grade: >95% by HPLC. CAS No. 87414-49-1. Molecular formula: C24H24O7. Mole weight: 424.44. | |
| Butyrolactone I - CAS 87414-49-1 | A cell-permeable and highly selective inhibitor of cyclin-dependent protein kinases (Cdks) that inhibits cell cycle progression at the G?/S and G?/M transitions. Group: Fluorescence/luminescence spectroscopy. |  |
| CAY10554 | Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively. Synonyms: BML-259; BML 259; CAY 10554; CAY-10554. Grade: ≥95%. CAS No. 267654-00-2. Molecular formula: C14H16N2OS. Mole weight: 260.4. | |
| CAY10574 | Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. CAY10574, also known as Cdk9 Inhibitor II, is a potent, selective inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with Ki of 13.3 μM and IC50 values 20 μM. Synonyms: CAY 10574; CAY-10574; Cdk9 Inhibitor II. Grade: ≥95%. CAS No. 140651-18-9. Molecular formula: C9H10N6O. Mole weight: 218.2. | |
| CBP501 | CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-specific phosphatase Cdc25C (cell division checkpoint 25 C); disruption of Cdc25C activity results in the inhibition of Cdc25C dephosphorylation of the mitotic cyclin-dependent kinase complex Cdc2/cyclin B, preventing entry into the mitotic phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent. Synonyms: CBP-501; CBP 501; H-D-Bpa-D-Ser-D-Trp-D-Ser-D-Phe(F5)-D-Cha-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-OH. CAS No. 565434-85-7. Molecular formula: C86H122F5N29O17. Mole weight: 1929.06. | |
| Cdk1/2 Inhibitor III | Cdk1/2 Inhibitor III is a selective inhibitor of Cdk1/2 with an IC50 of 2.1 μM for CDK1/cyclin B. It is a cell-permeable triazolo-diamine compound with anti-proliferative properties in various human cancer cells (IC50 = 20 nM, 35 nM and 92 nM in HCT-116, HeLa and A375 cells, respectively). Synonyms: Cyclin-dependent Kinase 1/2 Inhibitor III; 1H-1,2,4-Triazole-1-carbothioamide, 3-amino-5-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-; 3-Amino-5-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide; 3-amino-N-(2,6-difluorophenyl)-5-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide. Grade: >95%. CAS No. 443798-55-8. Molecular formula: C15H13F2N7O2S2. Mole weight: 425.44. | |
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