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Cycloguanil is a dihydrofolate reductase inhibitor. Synonyms: 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine. CAS No. 516-21-2. Molecular formula: C11H14ClN5. Mole weight: 251.718.
Cycloguanil-[d4] Hydrochloride
Cycloguanil-[d4] Hydrochloride is a labelled analogue of Cycloguanil. Cycloguanidine is a dihydrofolate reductase inhibitor and a metabolite of the antimalarial drug proguanil. Synonyms: Cycloguanil-d4 Hydrochloride. Grade: 98% by HPLC; 98% atom D. CAS No. 1189427-23-3. Molecular formula: C11H11D4Cl2N5. Mole weight: 292.2.
Cycloguanil-d4 Hydrochloride
Labeled antimalarial drug. Group: Biochemicals. Alternative Names: 1-(4-Chlorophenyl-d4)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine Hydrochloride; BN 2410; Chloroguanide-d4 Triazine Hydrochloride; Cycloguanil-d4 Hydrochloride; NSC 3074-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cycloguanil-[d6]
Cycloguanil-[d6] is a deuterium labelled analogue of Cycloguanil. Cycloguanil is an inhibitor of dihydrofolate reductase and a metabolite of proguanil. Synonyms: Chlorguanide triazine D6. Grade: >98%. Molecular formula: C11H8D6ClN5. Mole weight: 257.76.
Cycloguanil hydrochloride
Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12784A.
Cycloguanil hydrochloride
Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(4-Chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine Hydrochloride; BN 2410; Chloroguanide Triazine Hydrochloride; Cycloguanil Hydrochloride; NSC 3074. Product Category: Inhibitors. Appearance: White Solid. CAS No. 152-53-4. Molecular formula: C11H15Cl2N5. Mole weight: 288.18. Purity: 0.96. IUPACName: 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine hydrochloride. Canonical SMILES: CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C.Cl. Product ID: ACM152534. Alfa Chemistry ISO 9001:2015 Certified.
Cycloguanil hydrochloride
Cycloguanil is an active metabolite of proguanil, produced by the cytochrome P450 2C19 isoform. It is also an inhibitor of dihydrofolate reductase (DHFR) (Kis = 0.3 and 1.5 nM for Plasmodium and human forms, respectively). Uses: Antimalarials. Synonyms: Chloroguanide Triazine; NSC 3074; 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine monohydrochloride. Grade: ≥95%. CAS No. 152-53-4. Molecular formula: C11H14ClN5·HCl. Mole weight: 288.2.
Antimalarial drug. Group: Biochemicals. Alternative Names: 1-(4-Chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine Hydrochloride; BN 2410; Chloroguanide Triazine Hydrochloride; Cycloguanil Hydrochloride; NSC 3074. Grades: Highly Purified. CAS No. 152-53-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cycloguanil Nitrate
Cycloguanil Nitrate is the nitrate salt of Cycloguanil, an antimalarial drug. Synonyms: 1,3,5-Triazine-2,4-diamine, 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-, nitrate (1:1); s-Triazine, 4,6-diamino-1-(p-chlorophenyl)-1,2-dihydro-2,2-dimethyl-, mononitrate; 1-(4-Chlorophenyl)-6,6-dimethyl-1,3,5-triazinane-2,4-diimine nitrate; Cycloguanil nitrate salt. Grade: 95%. CAS No. 25332-44-9. Molecular formula: C11H15ClN6O3. Mole weight: 314.73.
Proguanil
Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase ( DHFR ) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0806.
Proguanil hydrochloride
Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase ( DHFR ) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 637-32-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0806A.
Proguanil hydrochloride
Proguanil hydrochloride, an antimalarial prodrug, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor. Uses: Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. Additional or Alternative Names: Chlorguanide, N1-(4-Chlorophenyl)-N5-isopropylbiguanide, Proguanil hydrochloride. Product Category: Solvents. CAS No. 637-32-1. Molecular formula: C11H17Cl2N5. Mole weight: 290.19. IUPACName: hydrogen 1-({amino[(4-chlorophenyl)amino]methylidene}amino)-N'-(propan-2-yl)methanimidamide chloride. Canonical SMILES: [H+].[Cl-].CC(C)N=C(N)N=C(N)NC1=CC=C(Cl)C=C1. ECNumber: 211-283-7. Product ID: ACM637321. Alfa Chemistry ISO 9001:2015 Certified.
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