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| Product | Description | |
|---|---|---|
| Cytarabine | Arabinofuranosyl-cytosine (ara-C) is an inhibitor of DNA synthesis used as an antineoplastic and antiviral. It is a chemotherapy agent used to treat cancers of white blood cells like acute myeloid leukemia (AML) and non-Hodgkin lymphoma. Uses: Arabinofuranosyl-cytosine (ara-c) is an inhibitor of dna synthesis. Synonyms: 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; (Arabinofuranosyl)cytosine; 1-(Arabinofuranosyl)cytosine; 1-(β-D-Arabinofuranosyl)cytosine; 1-β-D-Arabinosylcytosine; 1-β-Arabinofuranosylcytosine; 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine; Ac 1075; Alexan; Ara-C; Ara-cell; ara-Cytosine; Arabinocytosine; Arabinoside C; Arabitin; Aracytidine; Aracytin; Aracytine; Arafcyt; Citozar; Cyclocide; Cylocide; Cylocide N; Cytarabin; Cytarabinoside; Cytosar; Cytosar U; Cytosine arabinoside; Cytosine β-D-arabinofuranoside; Cytosine β-D-arabinoside; Cytosine-1-β-D-arabinofuranoside; Cytosine-1-β-arabinofuranoside; DepoCyt; DepoCyte; Erpalfa; Iretin; MK 8242; NSC 287459; NSC 63878; SCH 900242; Spongocytidine; Tarabine PFS; U 19920; U 19920A; Udicil. Grade: ≥95%. CAS No. 147-94-4. Molecular formula: C9H13N3O5. Mole weight: 243.22. |  |
| Cytarabine | Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity. Uses: Scientific research. Group: Natural products. Alternative Names: Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C. CAS No. 147-94-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-13605. |  |
| Cytarabine | Cytarabine. Group: Biochemicals. Grades: Purified. CAS No. 147-94-4. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Cytarabine | Pharmaceutical Secondary Standard; Certified Reference Material. Group: Pharmacopeia & metrological institutes standards. |  |
| Cytarabine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: 4-amino-1-beta-d-arabinofuranosylpyrimidin-2(1H)-one,Cytarabine. | |
| Cytarabine-13C-15N2 | Cytarabine-13C-15N2 is a labelled analogue of Cytarabine. Cytarabine is a chemotherapy drug used for the treatment of acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), etc. Grade: > 95%. Molecular formula: C8H13NO513C15N2. Mole weight: 246.2. | |
| Cytarabine-[13C3] | It is the isotope labelled analogue Cytarabine, which is used as a nucleoside analog and prodrug form of the DNA polymerase inhibitor ara-CTP. Synonyms: 4-amino-1-β-D-arabinofuranosyl-2(1H)pyrimidinone-13C3; Cytosine-β-D-arabinofuranoside-13C3. Grade: 98%. Molecular formula: C6[13C]3H13N3O5. Mole weight: 246.19. | |
| Cytarabine-13C3 (4-amino-1-b-D-arabinofuranosyl-2(1H)pyrimidinone-13C3 Cytosine-b-D-arabinofuranoside-13C3) | Labelled Cytarabine, a compound used as an antineoplastic and antiviral. A selective inhibitro of DNA synthesis. Does not inhibit RNA synthesis. Group: Biochemicals. Alternative Names: 4-amino-1-b-D-arabinofuranosyl-2(1H)pyrimidinone-13C3 Cytosine-b-D-arabinofuranoside-13C3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cytarabine-13C3 5-Monophosphate | A labeled derivative of Cytarabine, a potent cytotoxic-antiviral nucleoside. Group: Biochemicals. Alternative Names: 4-Amino-1-(5-O-phosphono- β-D-arabinofuranosyl)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cytarabine (4-amino-1-b-D-arabinofuranosyl-2(1H)pyrimidinone, Cytosine-b-D-arabinofuranoside) | Used as an antineoplastic and antiviral. A selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis. Group: Biochemicals. Alternative Names: 4-amino-1-b-D-arabinofuranosyl-2(1H)pyrimidinone, Cytosine-b-D-arabinofuranoside. Grades: Highly Purified. CAS No. 147-94-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Cytarabine 5'-Monophosphate | Ara-Cytidine-5'-monophosphate (ara-CMP) is a derivative of Cytarabine, a potent cytotoxic-antiviral nucleoside. Synonyms: Cytarabine monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 7075-11-8. Molecular formula: C9H14N3O8P (free acid). Mole weight: 323.20 (free acid). | |
| Cytarabine 5'-Monophosphate-[13C3] | Cytarabine-[13C3] 5'-Monophosphate is the labelled analogue of Cytarabine 5'-Monophosphate, which is a derivative of the synthetic antiviral nucleoside Cytarabine. Synonyms: Cytarabine-13C3 5'-Monophosphate; 4-Amino-1-(5-O-phosphono-β-D-arabinofuranosyl)-2(1H)-pyrimidinone-13C3; 1-β-D-Arabinofuranosylcytosine-13C3 5'-Monophosphate; Cytosine-13C3 Arabinoside Monophosphate. Grade: ≥96%; ≥98% atom 13C. Molecular formula: C6[13C]3H14N3O8P. Mole weight: 326.18. | |
| Cytarabine-d2 | Cytarabine-[d2] is the labelled analogue of Cytarabine, which could be used as an antineoplastic as well as an antiviral agent. Synonyms: Cytarabine-d2; Cytarabine-5,6-d2; 40632-26-6; 2(1H)-Pyrimidinone-5,6-d2, 4-amino-1-ss-D-arabinofuranosyl- (9CI); Cytosine-5,6-d2-1-ss-D-arabinofuranoside; Cytarabine-d2; 4-Amino-1-ss-D-arabinofuranosyl-2(1H)-pyrimidinone-5,6-d2; Cytarabine-5,6-D2; HY-13605S; MS-23467; CS-0255654; F90692. Grade: 98% by HPLC; 98% atom D. CAS No. 40632-26-6. Molecular formula: C9H11D2N3O5. Mole weight: 245.23. | |
| Cytarabine hydrochloride | Cytarabine, an antimetabolite analogue of cytidine with a modified sugar moiety, is an antimetabolic agent and DNA synthesis inhibitor. Synonyms: Cytosine arabinoside hydrochloride; 1-beta-D-Arabinofuranosylcytosine hydrochloride; Aracytidine hydrochloride; 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone hydrochloride; Arabinocytidine hydrochloride; Arabinofuranosylcytosine hydrochloride. Grade: 95%. CAS No. 69-74-9. Molecular formula: C9H14ClN3O5. Mole weight: 279.68. | |
| Cytarabine hydrochloride | Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride. CAS No. 69-74-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-13605A. | |
| Cytarabine Hydrochloride | Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV. Uses: Antitumor drugs. Product Category: Inhibitors. Appearance: Solid. CAS No. 69-74-9. Molecular formula: C9H14ClN3O5. Mole weight: 279.68. Purity: ≥97.0%. Canonical SMILES: O=C1N=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O2)N.Cl. Product ID: ACM69749-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cytarabine Impurity 23 (Hydrochloride) | Cytarabine Impurity 23 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ancitabine (Cyclocytidine) HCl; (2R,3R,3aS,9aR)-2-(hydroxymethyl)-6-imino-3,3a,6,9a-tetrahydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-ol hydrochloride. CAS No. 10212-25-6. Molecular formula: C9H11N3O4·HCl. Mole weight: 261.66. Catalog: APB10212256. | |
| Cytarabine Impurity 6 | Cytarabine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4S,5R)-2-(acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate. CAS No. 14057-18-2. Molecular formula: C15H18N2O9. Mole weight: 370.31. Catalog: APB14057182. | |
| Elacytarabine | Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 4055. CAS No. 188181-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14941. | |
| Elacytarabine | Elacytarabine (CP-4055) is the lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As a prodrug, CP-4055 is converted intracellularly into cytarabine triphosphate by deoxycytidine kinase and subsequently competes with cytidine for incorporation into DNA, thereby inhibiting DNA synthesis. Compared to cytarabine, CP-4055 shows increased cellular uptake and retention, resulting in increased activation by deoxycytidine kinase to cytarabine triphosphate, decreased deamination and deactivation by deoxycytidine deaminase, and increased inhibition of DNA synthesis. This agent also inhibits RNA synthesis, an effect not seen with cytarabine. Synonyms: CP-4055; CP 4055; CP4055; 5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine; 5'-Oleoyl cytarabine; (E)-((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate. CAS No. 188181-42-2. Molecular formula: C27H45N3O6. Mole weight: 507.67. | |
| 1-α-L-Arabinofuranosylcytosine | 1-α-L-Arabinofuranosylcytosine, also known as cytarabine (Ara-C), is a nucleoside analog consisting of a cytosine base attached to an α-L-arabinofuranose sugar. This compound is widely used as a chemotherapeutic agent, particularly in the treatment of hematological malignancies such as acute myeloid leukemia (AML). Its mechanism involves incorporation into DNA during replication, leading to chain termination and inhibition of DNA synthesis, thereby inducing apoptosis in rapidly dividing cancer cells. Synonyms: alpha-L-ara-cytidine; Cytarabine impurity 42; 4-Amino-1-α-L-arabinofuranosyl-2(1H)-pyrimidinone; 1-alpha-L-arabinofuranosyl cytosine; 4-Amino-1-[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one; α-L-Ara-Furan-C. Grade: ≥95%. CAS No. 16033-23-1. Molecular formula: C9H13N3O5. Mole weight: 243.22. | |
| 1- (b-D-Arabinofuranosyl) cytosine | 1- (b-D-Arabinofuranosyl) cytosine. Group: Biochemicals. Alternative Names: Cytosine-b-D-arabinofuranoside; Cytarabine; 4-Amino-1-(b-D-Arabinofuranosyl)-2(1H)pyrimidinone. Grades: Highly Purified. CAS No. 147-94-4. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H13N3O5. US Biological Life Sciences. | Worldwide |
| 1- (b-D-Arabinofuranosyl) cytosine 5'-triphosphate triethyammonium salt | 1- (b-D-Arabinofuranosyl) cytosine 5'-triphosphate triethyammonium salt. Group: Biochemicals. Alternative Names: Cytarabine 5'-triphosphate triethyammonium salt. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| 1- (b-D-Arabinofuranosyl) cytosine HCl | 1- (b-D-Arabinofuranosyl) cytosine HCl. Group: Biochemicals. Alternative Names: Cytosine b-D-arabinofuranoside HCl; Cytarabine HCl. Grades: Highly Purified. CAS No. 69-74-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H13N3O5·HCl. US Biological Life Sciences. | Worldwide |
| 1-β-D-Lyxofuranosylcytosine | 1-β-D-Lyxofuranosylcytosine is a nucleoside analog where a cytosine base is linked to a β-D-lyxofuranose sugar. Unlike the standard β-D-ribose in natural nucleosides, the lyxofuranose sugar has a different stereochemistry, which can influence its biological interactions. This compound is of interest in medicinal chemistry and biochemical research, where its unique structure may contribute to modified activity or specificity in nucleic acid-related processes, such as enzyme interactions or antiviral applications. Synonyms: Cytarabine impurity 4; 4-Amino-1-β-D-lyxofuranosyl-2(1H)-pyrimidinone; 1-beta-D-Lyxofuranosyl cytosine. Grade: ≥95%. CAS No. 18265-49-1. Molecular formula: C9H13N3O5. Mole weight: 243.22. | |
| 2,2'-Anhydrocytidine | 2,2'-Anhydrocytidine, an intriguing compound highly regarded in the biomedical field, serves as a critical subject of research owing to its profound prospects in combatting viral infections, especially those instigated by RNA viruses. Synonyms: Cytarabine Impurity H; (2R,3R,3aS,9aR)-2-(Hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-3-ol; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, (2R,3R,3aS,9aR)-; (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-6-imino-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, [2R-(2α,3β,3aβ,9aβ)]-; 2,2'-Anhydro(1-β-D-arabinofuranosyl)cytosine; 2,2'-Anhydroarabinosylcytosine; 2,2'-Cyclocytidine; 2,2'-O-Cyclocytidine; Ancitabine; Ancytabine; Cyclocytidine; O2,2'-Cyclocytidine; O2:2'-Anhydro-1-β-D-arabinosylcytosine; Cytarabine EP Impurity H. Grade: ≥95%. CAS No. 31698-14-3. Molecular formula: C9H11N3O4. Mole weight: 225.20. | |
| 2',5'-Anhydroarabinocytidine | 2',5'-Anhydroarabinocytidine is a modified nucleoside where the typical 3'-5' phosphodiester linkage between the sugar units is replaced by a 2',5'-anhydro linkage, connecting the sugar's 2' and 5' carbon atoms. The base is arabinocytidine, where the sugar is an arabinose derivative. This modification creates a unique structure that could affect the stability and interaction of the nucleoside with enzymes, such as nucleases, and may make it resistant to typical DNA or RNA degradation pathways. 2',5'-Anhydroarabinocytidine could have potential applications in nucleic acid-based therapies, where enhanced stability or altered enzymatic interactions are desired, and might be used for the development of antiviral drugs or in the synthesis of modified oligonucleotides for research purposes. Synonyms: Cytarabine Impurity F; 4-Amino-1-(2,5-anhydro-β-D-arabinofuranosyl)pyrimidin-2(1H)-one; Cytarabine EP impurity F; Cytarabine impurity 10 (or 1, 4, 17); 2',5'-Anhydro-1-(beta-D-arabinofuranosyl)cytosine; 4-Amino-1-(2,5-anhydro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone; (2',5'-Anhydroarabinosyl)cytosine; NSC 340843; 4-Amino-1-((1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 32830-01-6. Molecular formula: C9H11N3O4. Mole weight: 225.20. | |
| 2-Fluoroadenosine | Fludarabine is highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates than alkylating agents such as chlorambucil alone.Fludarabine is used in various combinations with cyclophosphamide, mitoxantrone, dexamethasone and rituximab in the treatment of indolent non-Hodgkins lymphomas. As part of the FLAG regimen, fludarabine is used together with cytarabine and granulocyte colony-stimulating factor in the treatment of acute myeloid leukaemia. Because of its immunosuppressive effects, fludarabine is also used in some conditioning regimens prior to non myeloablative allogeneic stem cell transplant. Synonyms: Fludarabine; 2-Fluoro Adenosine; 6-Amino-2-fluoro-9-beta-D-ribofuranosylpurine. Grade: 98%. CAS No. 146-78-1. Molecular formula: C10H12FN5O4. Mole weight: 285.235. | |
| 5-Hydroxy-arabinouridine | 5-Hydroxy-arabinouridine is a remarkable compound, effectively impeding the expansion of aberrant cells, while concurrently evoking programmed cell death. Moreover, this awe-inspiring compound exhibiting the potential to synergistically augment the efficacy of various anticancer compounds when administered concomitantly. Synonyms: 1-(β-D-Arabinofuranosyl)-5-hydroxy-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione; Cytarabine Impurity 17; 1-β-D-Arabinofuranosyl-5-hydroxyuracil; NSC 117925. Grade: ≥95%. CAS No. 69321-95-5. Molecular formula: C9H12N2O7. Mole weight: 260.20. | |
| 5-Methyl-4'-thiouridine | 5-Methyl-4'-thiouridine, a modified RNA base nucleoside, has been found to exhibit significant therapeutic potential against a variety of cancer types - notably leukemia and breast cancer - via its demonstrated ability to retard tumor growth and initiate programmed cell death in malignant cells. Further, this innovative compound has been shown to enhance the efficacy of fluorouracil and cytarabine, two commonly used chemotherapeutic drugs. Synonyms: 1-(4-Thio-beta-D-ribofuranosyl)-5-methyluracil; 1-(4'-Thio-beta-ribofuranosyl)thymine; Uridine, 5-methyl-4'-thio-; 1-Ribo-4'-thiothymine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 6741-71-5. Molecular formula: C10H14N2O5S. Mole weight: 274.29. | |
| 5-Methylarabinosylcytosine | An impurity of Cytarabine. Cytarabine is an antineoplastic anti-metabolite used in the treatment of several forms of leukemia including acute myelogenous leukemia and meningeal leukemia. Synonyms: Cytarabine Impurity I; 5-Methyl arabinocytidine; Cytarabine impurity 10; Cytarabine EP impurity I; 1-b-Arabinofuranosyl-5-methylcytosine; Arabino-5-methylcytidine; 5-Methyl ara-C; 4-Amino-1-β-D-arabinofuranosyl-5-methyl-2(1H)-pyrimidinone; 1-β-D-Arabinofuranosyl-5-methylcytosine; 4-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 4-Amino-1-β-D-arabinofuranosyl-5-methylpyrimidin-2(1H)-one; NSC 96372; NSC 529544. Grade: ≥95%. CAS No. 6829-31-8. Molecular formula: C10H15N3O5. Mole weight: 257.24. | |
| 5-Methylcytidine | 5-Methylcytidine is a derivative of Cytidine, found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling. Synonyms: Cytarabine Impurity G; 4-Amino-5-methyl-1-β-D-ribofuranosylpyrimidin-2(1H)-one; 5-Me-rC; 5-Methyl-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; NSC 363933; 5-Methyl-D-cytidine; 5-Methyl-ribo Cytidine; Cytarabine EP Impurity G. Grade: ≥98% by HPLC. CAS No. 2140-61-6. Molecular formula: C10H15N3O5. Mole weight: 257.24. | |
| Ancitabine hydrochloride | Ancitabine hydrochloride is the precursor of the anticancer agent Cytarabine (HY-13605), which targets targets related to cell metabolism and proliferation. Ancitabine hydrochloride can inhibit tumor cell proliferation, interfere with the DNA synthesis process of tumor cells, and prevent cell division. Under alkaline pH conditions, Ancitabine hydrochloride can be quantitatively converted into Cytarabine and can be used in the study of cancers such as colorectal cancer [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyclocytidine hydrochloride; Cyclo-CMP hydrochloride; Cyclo-C. CAS No. 10212-25-6. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-N0093. | |
| ara-Cytidine-5'-diphosphate (ara-CDP) | Ara-Cytidine-5'-diphosphate (ara-CDP), an innovative nucleotide analog, plays a crucial role in the realm of anti-cancer therapy by thwarting DNA synthesis and triggering apoptosis in cancer cells. Known for its efficacy in treating acute myeloid leukemia and non-Hodgkin lymphoma, this compound is available in several formats and can be delivered through both oral and injection routes. Its versatile therapeutic potential has revolutionized cancer treatment paradigms by novelly combining precise cellular targeting with extensive delivery options. Synonyms: Cytarabine diphosphate; Cytidine-arabinofuranoside-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H15N3O11P2 (free acid). Mole weight: 403.17 (free acid). | |
| CBF beta-Runx1 Inhibitor II, Ro5-3335 ([7-chloro-5-(2-pyrryl)-3H-1,4 benzodiazapin-2-(H)-one], Ro53335, CBFalpha-CBFbeta Inhibitor II) | A cell-permeable benzodiazepine that suppresses CBFalpha/Runx1-CBFbeta transactivation activity (25uM; 293-0 cells) via direct bindings to both subunits of the heterodimeric transcription factor complex. Shown to inhibit oncogenic fusion CBFB-MYH11-, TEL-RUNX1-, and RUNX1-ETO-, dependent leukemia cells proliferation (IC50 = 1.1 to 21.7uM) in vitro and more effectively reduce peripheral blood c-kit+ population (300mg/kg/d via animal feed) than Cytarabine in a murine Cbfb-MYH11 leukemia model in vivo. Comparing to CBFbeta-Runx1 Inhibitor I, Ro5-3335 modulates the Runx1-CBFbeta heterodimer formation without completely disrupting the subunits interaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 30195-30-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Chemotherapy Drug Library | 51 Chemotherapeutic drugs that can be used for high-throughput and high-content screening. - Includes common chemotherapy drugs such as paclitaxel, cyclophosphamide, cytarabine, doxorubicin, etc. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure, high purity and reduce the false-positive rates. Uses: Scientific use. Product Category: L2151. Categories: Chemotherapy Drug Libraries. |  |
| Cytidine | Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. Synonyms: Cytarabine Impurity E; 4-Amino-1-β-D-ribofuranosylpyrimidin-2(1H)-one; Cytosine riboside; MK-0431; MK 0431; MK0431; ribo Cytidine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(amino)pyrimidin-2(1H)-one; 1-(β-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine; 1-β-D-Ribofuranosylcytosine; 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; NSC 20258; β-D-Cytidine; Cytarabine EP Impurity E. Grade: ≥98% by HPLC. CAS No. 65-46-3. Molecular formula: C9H13N3O5. Mole weight: 243.22. | |
| Cytosine | Cytosine is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (anamine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. Synonyms: Cytarabine Impurity C; 4-Aminopyrimidin-2(1H)-one; 6-Amino-2(1H)-pyrimidinone; 4-Amino-1H-pyrimidin-2-one; 4-Amino-2(1H)-pyrimidinone; 4-Amino-2-hydroxypyrimidine; 4-Aminouracil; Gemcitabine EP Impurity A; Lamivudine EP Impurity E; 2-Hydroxy-4-pyrimidinamine; 4-Amino-2-oxo-1,2-dihydropyrimidine; Cytosines; Cytosinimine; NSC 27787; Cytarabine EP Impurity C; Gemcitabine hydrochloride EP Impurity A. Grade: 98%. CAS No. 71-30-7. Molecular formula: C4H5N3O. Mole weight: 111.10. | |
| Enocitabine (N- (1-B-D-Arabinofuranosyl-1, 2-dihydro-2-oxo-4-pyrimidinyl) docosanamide, Behenoylcytosine Arabinoside, BH-AC, NSC-239336, Sunrabin) | An antineoplastic. A derivative of Cytarabine. Group: Biochemicals. Alternative Names: N- (1-B-D-Arabinofuranosyl-1, 2-dihydro-2-oxo-4-pyrimidinyl) docosanamide, Behenoylcytosine Arabinoside, BH-AC, NSC-239336, Sunrabin. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Fazarabine | Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. Synonyms: CCRIS 93; CCRIS-93; CCRIS93; NSC 281272; NSC-281272; NSC281272; Ara-AC; 5-Azacytosine arabinoside; 1-beta-D-Arabinofuranosyl-5-azacytosine. CAS No. 65886-71-7. Molecular formula: C8H12N4O5. Mole weight: 244.20. | |
| Fosteabine | Fosteabine is an oral and prodrug cytarabine analogue. It is resistant to deoxycytidine deaminase. Synonyms: Cytarabine ocfosfate; Stearyl-ara-cmp; YNK 01; YNK-01; YNK01. CAS No. 73532-83-9. Molecular formula: C27H50N3O8P. Mole weight: 575.68. | |
| Gemcitabine elaidate hydrochloride | Gemcitabine elaidate is a lipophilic prodrug form of the nucleoside analog gemcitabine that contains an elaidic acid moiety. Gemcitabine elaidate inhibits growth of gemcitabine-sensitive L1210/L5, BCLO, and A2780 cells (IC50s = 0.0033, 0.0042, and 0.0025 μM, respectively) but not cytarabine-resistant L4A6 and Bara-C cells (IC50s = 16 and 13 μM, respectively) or gemcitabine-resistant AG6000 cells (IC50 = 91 μM). Synonyms: CO-101 hydrochloride; CP-4126 hydrochloride; Gemcitabine 5'-elaidate hydrochloride. Grade: ≥97%. CAS No. 2918768-08-6. Molecular formula: C27H44ClF2N3O5. Mole weight: 564.11. | |
| Sapacitabine | Sapacitabine is an orally available nucleoside analog proagent that is structurally related to cytarabine. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS682; CYC682. CAS No. 151823-14-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16445. | |
| Spongouridine | 1-β-D-Arabinofuranosyluracil is an antiviral agent. It is used for the treatment of severe acute respiratory syndrome (SARS). It is also an impurity of Cytarabine. Synonyms: Arauridine; 1-(β-D-Arabinofuranosyl)uracil; Uracil-1-β-D-arabinofuranoside; 1-β-D-Arabinofuranosyl-2,4(1H,3H)-pyrimidinedione; Ara-U; Arabinosyluracil; NSC 68928; Cytarabine Impurity A; Cytarabine EP Impurity A; 1-β-D-Arabinofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Arabinofuranosyluracil; Arabinofuranosyluracil; Spongouridin; Uracil arabinoside; Uracil β-D-arabinofuranoside. Grade: ≥95%. CAS No. 3083-77-0. Molecular formula: C9H12N2O6. Mole weight: 244.20. | |
| Uracil | Uracil is one of the four nucleobases in the nucleic acid of RNA, and can be used for drug delivery and as a pharmaceutical. Synonyms: Cytarabine Impurity D; Pyrimidin-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxopyrimidine; 2,4-Pyrimidinedione; Pirod; Pyrod; Fluorouracil Impurity C; 1,2,3,4-Tetrahydropyrimidine-2,4-dione; 2,4-Dihydroxypyrimidine; 2,4-Pyrimidinediol; 4-Hydroxyuracil; Hybar X; NSC 3970; Lamivudine EP Impurity F; Fluorouracil EP Impurity C; Cytarabine EP Impurity D. Grade: >98%. CAS No. 66-22-8. Molecular formula: C4H4N2O2. Mole weight: 112.09. | |
| Uracil arabinoside | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: Uracil beta-D-arabinofuranoside, Nelarabine related, Arauridine,Ara-U, Spongouridin, Spongouridine, GR 46541X, Cytarabine Imp. A (EP), 1-beta-d-arabinofuranosylpyrimidine-2,4(1H,3H)-dione (uracil arabonoside), Uracil Arabinofuranoside, Arabinofuranosyluracil, Uracil, 1-beta-D-arabinofuranosyl- (6CI,7CI,8CI), Arabinosyluracil, 1-beta-D-Arabinofuranosyluracil, Uracil arabinoside, 282U85, NSC 68928. | |
| Uridine | Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond. Synonyms: Cytarabine Impurity B; 1-β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Ribofuranosyluracil; NSC 20256; Uracil riboside; 1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Uridin; β-Uridine; Cytarabine EP Impurity B. Grade: ≥98% by HPLC. CAS No. 58-96-8. Molecular formula: C9H12N2O6. Mole weight: 244.20. | |
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