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Cytarabine Impurity 23 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ancitabine (Cyclocytidine) HCl; (2R,3R,3aS,9aR)-2-(hydroxymethyl)-6-imino-3,3a,6,9a-tetrahydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-ol hydrochloride. CAS No. 10212-25-6. Molecular formula: C9H11N3O4·HCl. Mole weight: 261.66. Catalog: APB10212256.
Cytarabine Impurity 6
Cytarabine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4S,5R)-2-(acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate. CAS No. 14057-18-2. Molecular formula: C15H18N2O9. Mole weight: 370.31. Catalog: APB14057182.
1-α-L-Arabinofuranosylcytosine
1-α-L-Arabinofuranosylcytosine, also known as cytarabine (Ara-C), is a nucleoside analog consisting of a cytosine base attached to an α-L-arabinofuranose sugar. This compound is widely used as a chemotherapeutic agent, particularly in the treatment of hematological malignancies such as acute myeloid leukemia (AML). Its mechanism involves incorporation into DNA during replication, leading to chain termination and inhibition of DNA synthesis, thereby inducing apoptosis in rapidly dividing cancer cells. Synonyms: alpha-L-ara-cytidine; Cytarabine impurity 42; 4-Amino-1-α-L-arabinofuranosyl-2(1H)-pyrimidinone; 1-alpha-L-arabinofuranosyl cytosine; 4-Amino-1-[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one; α-L-Ara-Furan-C. Grade: ≥95%. CAS No. 16033-23-1. Molecular formula: C9H13N3O5. Mole weight: 243.22.
1-β-D-Lyxofuranosylcytosine
1-β-D-Lyxofuranosylcytosine is a nucleoside analog where a cytosine base is linked to a β-D-lyxofuranose sugar. Unlike the standard β-D-ribose in natural nucleosides, the lyxofuranose sugar has a different stereochemistry, which can influence its biological interactions. This compound is of interest in medicinal chemistry and biochemical research, where its unique structure may contribute to modified activity or specificity in nucleic acid-related processes, such as enzyme interactions or antiviral applications. Synonyms: Cytarabine impurity 4; 4-Amino-1-β-D-lyxofuranosyl-2(1H)-pyrimidinone; 1-beta-D-Lyxofuranosyl cytosine. Grade: ≥95%. CAS No. 18265-49-1. Molecular formula: C9H13N3O5. Mole weight: 243.22.
2,2'-Anhydrocytidine
2,2'-Anhydrocytidine, an intriguing compound highly regarded in the biomedical field, serves as a critical subject of research owing to its profound prospects in combatting viral infections, especially those instigated by RNA viruses. Synonyms: Cytarabine Impurity H; (2R,3R,3aS,9aR)-2-(Hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-3-ol; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, (2R,3R,3aS,9aR)-; (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-6-imino-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, [2R-(2α,3β,3aβ,9aβ)]-; 2,2'-Anhydro(1-β-D-arabinofuranosyl)cytosine; 2,2'-Anhydroarabinosylcytosine; 2,2'-Cyclocytidine; 2,2'-O-Cyclocytidine; Ancitabine; Ancytabine; Cyclocytidine; O2,2'-Cyclocytidine; O2:2'-Anhydro-1-β-D-arabinosylcytosine; Cytarabine EP Impurity H. Grade: ≥95%. CAS No. 31698-14-3. Molecular formula: C9H11N3O4. Mole weight: 225.20.
2',5'-Anhydroarabinocytidine
2',5'-Anhydroarabinocytidine is a modified nucleoside where the typical 3'-5' phosphodiester linkage between the sugar units is replaced by a 2',5'-anhydro linkage, connecting the sugar's 2' and 5' carbon atoms. The base is arabinocytidine, where the sugar is an arabinose derivative. This modification creates a unique structure that could affect the stability and interaction of the nucleoside with enzymes, such as nucleases, and may make it resistant to typical DNA or RNA degradation pathways. 2',5'-Anhydroarabinocytidine could have potential applications in nucleic acid-based therapies, where enhanced stability or altered enzymatic interactions are desired, and might be used for the development of antiviral drugs or in the synthesis of modified oligonucleotides for research purposes. Synonyms: Cytarabine Impurity F; 4-Amino-1-(2,5-anhydro-β-D-arabinofuranosyl)pyrimidin-2(1H)-one; Cytarabine EP impurity F; Cytarabine impurity 10 (or 1, 4, 17); 2',5'-Anhydro-1-(beta-D-arabinofuranosyl)cytosine; 4-Amino-1-(2,5-anhydro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone; (2',5'-Anhydroarabinosyl)cytosine; NSC 340843; 4-Amino-1-((1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 32830-01-6. Molecular formula: C9H11N3O4. Mole weight: 225.20.
5-Hydroxy-arabinouridine
5-Hydroxy-arabinouridine is a remarkable compound, effectively impeding the expansion of aberrant cells, while concurrently evoking programmed cell death. Moreover, this awe-inspiring compound exhibiting the potential to synergistically augment the efficacy of various anticancer compounds when administered concomitantly. Synonyms: 1-(β-D-Arabinofuranosyl)-5-hydroxy-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione; Cytarabine Impurity 17; 1-β-D-Arabinofuranosyl-5-hydroxyuracil; NSC 117925. Grade: ≥95%. CAS No. 69321-95-5. Molecular formula: C9H12N2O7. Mole weight: 260.20.
5-Methylarabinosylcytosine
An impurity of Cytarabine. Cytarabine is an antineoplastic anti-metabolite used in the treatment of several forms of leukemia including acute myelogenous leukemia and meningeal leukemia. Synonyms: Cytarabine Impurity I; 5-Methyl arabinocytidine; Cytarabine impurity 10; Cytarabine EP impurity I; 1-b-Arabinofuranosyl-5-methylcytosine; Arabino-5-methylcytidine; 5-Methyl ara-C; 4-Amino-1-β-D-arabinofuranosyl-5-methyl-2(1H)-pyrimidinone; 1-β-D-Arabinofuranosyl-5-methylcytosine; 4-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 4-Amino-1-β-D-arabinofuranosyl-5-methylpyrimidin-2(1H)-one; NSC 96372; NSC 529544. Grade: ≥95%. CAS No. 6829-31-8. Molecular formula: C10H15N3O5. Mole weight: 257.24.
5-Methylcytidine
5-Methylcytidine is a derivative of Cytidine, found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling. Synonyms: Cytarabine Impurity G; 4-Amino-5-methyl-1-β-D-ribofuranosylpyrimidin-2(1H)-one; 5-Me-rC; 5-Methyl-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; NSC 363933; 5-Methyl-D-cytidine; 5-Methyl-ribo Cytidine; Cytarabine EP Impurity G. Grade: ≥98% by HPLC. CAS No. 2140-61-6. Molecular formula: C10H15N3O5. Mole weight: 257.24.
Cytidine
Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. Synonyms: Cytarabine Impurity E; 4-Amino-1-β-D-ribofuranosylpyrimidin-2(1H)-one; Cytosine riboside; MK-0431; MK 0431; MK0431; ribo Cytidine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(amino)pyrimidin-2(1H)-one; 1-(β-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine; 1-β-D-Ribofuranosylcytosine; 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; NSC 20258; β-D-Cytidine; Cytarabine EP Impurity E. Grade: ≥98% by HPLC. CAS No. 65-46-3. Molecular formula: C9H13N3O5. Mole weight: 243.22.
Cytosine
Cytosine is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (anamine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. Synonyms: Cytarabine Impurity C; 4-Aminopyrimidin-2(1H)-one; 6-Amino-2(1H)-pyrimidinone; 4-Amino-1H-pyrimidin-2-one; 4-Amino-2(1H)-pyrimidinone; 4-Amino-2-hydroxypyrimidine; 4-Aminouracil; Gemcitabine EP Impurity A; Lamivudine EP Impurity E; 2-Hydroxy-4-pyrimidinamine; 4-Amino-2-oxo-1,2-dihydropyrimidine; Cytosines; Cytosinimine; NSC 27787; Cytarabine EP Impurity C; Gemcitabine hydrochloride EP Impurity A. Grade: 98%. CAS No. 71-30-7. Molecular formula: C4H5N3O. Mole weight: 111.10.
Spongouridine
1-β-D-Arabinofuranosyluracil is an antiviral agent. It is used for the treatment of severe acute respiratory syndrome (SARS). It is also an impurity of Cytarabine. Synonyms: Arauridine; 1-(β-D-Arabinofuranosyl)uracil; Uracil-1-β-D-arabinofuranoside; 1-β-D-Arabinofuranosyl-2,4(1H,3H)-pyrimidinedione; Ara-U; Arabinosyluracil; NSC 68928; Cytarabine Impurity A; Cytarabine EP Impurity A; 1-β-D-Arabinofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Arabinofuranosyluracil; Arabinofuranosyluracil; Spongouridin; Uracil arabinoside; Uracil β-D-arabinofuranoside. Grade: ≥95%. CAS No. 3083-77-0. Molecular formula: C9H12N2O6. Mole weight: 244.20.
Uracil
Uracil is one of the four nucleobases in the nucleic acid of RNA, and can be used for drug delivery and as a pharmaceutical. Synonyms: Cytarabine Impurity D; Pyrimidin-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxopyrimidine; 2,4-Pyrimidinedione; Pirod; Pyrod; Fluorouracil Impurity C; 1,2,3,4-Tetrahydropyrimidine-2,4-dione; 2,4-Dihydroxypyrimidine; 2,4-Pyrimidinediol; 4-Hydroxyuracil; Hybar X; NSC 3970; Lamivudine EP Impurity F; Fluorouracil EP Impurity C; Cytarabine EP Impurity D. Grade: >98%. CAS No. 66-22-8. Molecular formula: C4H4N2O2. Mole weight: 112.09.
Uridine
Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond. Synonyms: Cytarabine Impurity B; 1-β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Ribofuranosyluracil; NSC 20256; Uracil riboside; 1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Uridin; β-Uridine; Cytarabine EP Impurity B. Grade: ≥98% by HPLC. CAS No. 58-96-8. Molecular formula: C9H12N2O6. Mole weight: 244.20.
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