Dabrafenib Suppliers USA
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Product | Description | |
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Dabrafenib Mesylate Quick inquiry Where to buy Suppliers range | Dabrafenib, also known as GSK2118436, is an orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B-raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B-raf belongs to the the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which may be constitutively activated due to BRAF gene mutations. On May 29, 2013, FDA approved this drug. Synonyms: N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide methanesulfonate; Dabrafenib mesylate; GSK 2118436B; GSK2118436B; GSK-2118436B; GSK2118436 Methane sulfonate salt; Brand name: Taflinar. Grades: >98%. CAS No. 1195768-06-9. Molecular formula: C24H24F3N5O5S3. Mole weight: 615.67. | |
Dabrafenib Mesylate Quick inquiry Where to buy Suppliers range | Dabrafenib Mesylate. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Alternative Names: Benzenesulfonamide, N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-, methanesulfonate (1:1), Dabrafenib mesylate, GSK 2118436 methanesulfonate salt, GSK 2118436B, N-[3-[5-(2-Aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide methanesulfonic acid, GSK 2118436B. CAS No. 1195768-06-9. Pack Sizes: 10MG. IUPAC Name: N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1, 3-thiazol-4-yl]-2-fluorophenyl]-2, 6-difluorobenzenesulfonamide; methanesulfonic acid. Molecular formula: C23H20F3N5O2S2.CH4O3S. Mole weight: 615.67. Catalog: APS1195768069. SMILES: CC (C) (C)c1nc (c2cccc (NS (=O) (=O)c3c (F)cccc3F)c2F)c (s1)c4ccnc (N)n4. CS (=O) (=O)O. Format: Neat. Shipping: Room Temperature. | |
2, 6-Difluoro Benzene sulfonyl Chloride Quick inquiry Where to buy Suppliers range | 2, 6-Difluoro Benzene sulfonyl chloride is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 2, 6-Difluoro Benzene sulfonyl chloride is also a potential inhibitor of zinc proteases. Group: Biochemicals. Grades: Highly Purified. CAS No. 60230-36-6. Pack Sizes: 5g, 10g. Molecular Formula: C6H3ClF2O2S, Molecular Weight: 212.6. US Biological Life Sciences. | Worldwide |