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| Product | Description | |
|---|---|---|
| DAMGO | DAMGO is a highly selective peptide agonist of the μ opioid receptor. Uses: Analgesics, opioid. Synonyms: Y-d-Ala-G-Me-Phe-G-ol; L-tyrosyl-D-alanyl-glycyl-N-methyl-L-phenylalanyl-glycinol; DAGO; glyol; Dagol; 2-Ala-4-mephe-5-gly-enkephalin; (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin. Grade: ≥95%. CAS No. 78123-71-4. Molecular formula: C26H35N5O6. Mole weight: 513.59. |  |
| DAMGO | DAMGO is a μ-opioid receptor ( μ-OPR ) selective agonist with a K d of 3.46 nM for native μ-OPR [1]. Uses: Scientific research. Group: Peptides. CAS No. 78123-71-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0210. |  |
| DAMGO | Highly selective peptide agonist for the μ opioid receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 78123-71-4. Pack Sizes: 1mg. Molecular Formula: C26H35N5O6. US Biological Life Sciences. |  Worldwide |
| DAMGO TFA | DAMGO is a selective peptide agonist of the μ-opioid receptor. Grade: 99%. CAS No. 950492-85-0. Molecular formula: C28H36F3N5O8. Mole weight: 627.61. | |
| DAMGO TFA | DAMGO TFA is a μ-opioid receptor ( μ-OPR ) selective agonist with a K d of 3.46 nM for native μ-OPR [1]. Uses: Scientific research. Group: Peptides. CAS No. 950492-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-P0210B. | |
| BMS 986122 | BMS 986122 is a positive allosteric modulator of the μ-Opioid receptor. It significantly increases the inhibition of forskolin-stimulated adenylyl cyclase activity produced by an EC10 (30 pM) concentration of endomorphin-I in CHO-μ cells. BMS 986122 potentiates endomorphin 1-induced inhibition of forskolin-stimulated adenylyl cyclase activity in CHO cells expressing human recombinant μ-opioid receptors with EC50 of 8.9 μM. It also enhances [35S]GTPγ binding stimulated by the μ-opioid agonist DAMGO by 7- and 4.5-fold in C6μ glioma cell membranes. Synonyms: BMS-986122; BMS986122; 2-(3-bromo-4-methoxyphenyl)-3-[(4-chlorophenyl)sulfonyl]-thiazolidine. Grade: ≥98%. CAS No. 313669-88-4. Molecular formula: C16H15BrClNO3S2. Mole weight: 448.8. | |
| CMPD101 | CMPD101 is a novel, potent and selective G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) inhibitor (IC50 values are 35 and 32 nM at GRK2 and GRK3 respectively). CMPD101 exhibits selectivity for GRK2/3 over GRK1/5 and reduces DAMGO-induced desensitization and internalization of μ-opioid receptors. CMPD101 has been shown to potentiate phosphatidylinositol 4,5-bisphosphate (PIP2) depletion and slow agonist-induced desensitization of protease-activated receptor 2 (PAR2). Uses: Designed for use in research and industrial production. Additional or Alternative Names: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.47. Purity: >98%. IUPACName: 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide. Canonical SMILES: O=C(NCC1=CC=CC=C1C(F)(F)F)C2=CC=CC(NCC3=NN=C(C4=CC=NC=C4)N3C)=C2. Product ID: ACM865608113. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CMPD101 | CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DAMGO-induced desensitization and internalization of μ-opioid receptors. Synonyms: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide. Grade: 98%. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.46. | |
| Dago | Dago. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DAMGO, glyol, Dagol, DAGO, DAMGE, Tyr-ala-gly-(nme)phe-gly-ol, 2-Ala-4-mephe-5-gly-enkephalin, Ala(2)-mephe(4)-gly-ol(5) enkephalin, RX 783006, (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin, Enkephalin, ala(2)-mephe(4)-gly(5)-, Enkephalin, alanyl(2)-methylphenylalanyl(4)-glycine(5)-, Enkephalin, Ala(2)-MePhe(4)-Gly-ol(5)-, L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-, 78123-71-4, (2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]-methylamino]-N-(2-hydroxyethyl)-3-phenylpropanamide, DAGn, AC1NUWDS, [3H]DAMGO, SureCN725750. Product Category: Heterocyclic Organic Compound. CAS No. 78123-71-4. Molecular formula: C26H35N5O6. Mole weight: 513.59. Purity: 0.96. IUPACName: (2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide. Canonical SMILES: CC(C(=O)NCC(=O)N(C)C(CC1=CC=CC=C1)C(=O)NCCO)NC(=O)C(CC2=CC=C(C=C2)O)N. Density: 1.271g/cm³. Product ID: ACM78123714. Alfa Chemistry ISO 9001:2015 Certified. | |
| [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt | DAMGO is an analog of μ-Receptor-specific enkephalin. It stimulates calcium-activated adenylyl cyclases related cAMP production. Synonyms: DAMGO acetate; DAGO acetate; Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol; L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide monoacetate (salt); L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-alpha-methyl-L-phenylalaninamide monoacetate (salt). Grade: 95%. CAS No. 100929-53-1. Molecular formula: C28H39N5O8. Mole weight: 573.64. | |
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