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| Product | Description | |
|---|---|---|
| Dantrolene | Dantrolene is an orally active, non-competitive glutathione reductase inhibitor with a K i of 111.6 μM and an IC 50 of 52.3 μM. Dantrolene is also a calcium channel protein inhibitor. Dantrolene inhibits the release of Ca 2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: F 368. CAS No. 7261-97-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12542. |  |
| Dantrolene | Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. Synonyms: Dantrolenum [INN-Latin]; Dantroleno [INN-Spanish]; Dantrolenum; Ryanodex; 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin; Hydantoin, 1-((5-(p-nitrophenyl)furfurylidene)amino)-; 1-(((5-(4-Nitrophenyl)-2-furanyl)methylene)amino)-2,4-imidazolidinedione; 2,4-Imidazolidinedione, 1-(((5-(4-nitrophenyl)-2-furanyl)methylene)amino)-; 833480-90-3; 1-[[5-(p-Nitrophenyl)furfurylidene]amino]hydantoin; 1-(((5-(4-Nitrophenyl)furan-2-yl)methylene)amino)imidazolidine-2,4-dione; 1-[[[5-(4-Nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione; 2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-. Grade: 99% (HPLC). CAS No. 7261-97-4. Molecular formula: C14H10N4O5. Mole weight: 314.25. |  |
| Dantrolene | Dantrolene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DANTROLENE;DANTROLENE FREE BASE (FOR R&D ONLY). Product Category: Heterocyclic Organic Compound. CAS No. 85008-71-5. Molecular formula: C14H10N4O5. Mole weight: 314.25. Purity: 0.96. IUPACName: 1-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione. Canonical SMILES: C1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]. ECNumber: 230-684-8. Product ID: ACM85008715. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Dantrolene | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| Dantrolene-13C3 | A labeled muscle relaxant (skeletal). Used in the treatment of malignant hyperthermia. Group: Biochemicals. Alternative Names: 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione-13C3; Dantrium-13C3. Grades: Highly Purified. CAS No. 1185234-99-4. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Dantrolene-[13C3] | Dantrolene-[13C3] is a labelled Dantrolene. Dantrolene is a muscle relaxant that acts via inhibiting Ca2+ ions release from sarcoplasmic reticulum. Dantrolene is used in the treatment of malignant hyperthermia. Synonyms: Dantrolene 13C3; 1-{[1-[5-(4-Nitrophenyl)-furan-2-yl]-methylidene]-amino}-imidazolidine-2,4-dione-[2,4,5-13C3]. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1185234-99-4. Molecular formula: C11[13C]3H10N4O5. Mole weight: 317.28. | |
| Dantrolene Impurity 2 | 5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone is an impurity in the synthesis of Dantrolene, a muscle relaxant (skeletal). Dantrolene is used in the treatment of malignant hyperthermia. Synonyms: 5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone; [(Aminocarbonyl)[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazino]acetic Acid; Dantrolene Impurity. Grade: > 95%. CAS No. 57268-33-4. Molecular formula: C14H12N4O6. Mole weight: 332.27. | |
| Dantrolene Impurity 3 | 2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester is an intermediate used in the synthesis of 1-(5-Phenylfurfurylideneamino)hydantoins. Synonyms: 2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester. Grade: > 95%. CAS No. 55227-60-6. Molecular formula: C16H16N4O6. Mole weight: 360.32. | |
| Dantrolene Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Dantrolene Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Dantrolene Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Dantrolene sodium | Dantrolene sodium. CAS No. 14663-23-1. Product ID: 8-01327. Molecular formula: C14H9N4NaO5 3.5H2O. Mole weight: 399.29. |  |
| Dantrolene sodium | Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor with a K i of 111.6 μM and an IC 50 of 52.3 μM. Dantrolene sodium is also a calcium channel protein inhibitor. Dantrolene sodium inhibits the release of Ca 2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene sodium offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: F 440. CAS No. 14663-23-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-14657. | |
| Dantrolene sodium | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Dantrolene Sodium | Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It suppresses the release of calcium previously sequestered by skeletal, but not cardiac, muscle sarcoplasmic reticulum. Synonyms: Dantrolene sodium salt; Dantrium; Sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate. Grade: 98.0%~102.0%. CAS No. 14663-23-1. Molecular formula: C14H9N4NaO5. Mole weight: 336.239. | |
| Dantrolene sodium hemiheptahydrate | Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by blocking excitation-contraction coupling in the muscle fiber. Uses: Muscle relaxants, central. Synonyms: Dantrolene sodium salt; Dantrium; Sodium dantrolene. Grade: ≥99%. CAS No. 24868-20-0. Molecular formula: C14H9N4O5·7/2H2O·Na. Mole weight: 399.29. | |
| Dantrolene sodium hemiheptahydrate | Dantrolene sodium hemiheptahydrate is an orally active, non-competitive glutathione reductase inhibitor with a K i of 111.6 μM and an IC 50 of 52.3 μM. Dantrolene sodium hemiheptahydrate is also a calcium channel protein inhibitor. Dantrolene sodium hemiheptahydrate inhibits the release of Ca 2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene sodium hemiheptahydrate offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dantrolene sodium hydrate. CAS No. 24868-20-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-12542A. | |
| Dantrolene Sodium Salt, Anhydrous | Dantrolene sodium is a skeletal muscle relaxant, which inhibits intracellular Ca 2+release from the sarcoplasmic reticulum. Group: Biochemicals. Alternative Names: 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolinedione Sodium Salt; Dantrium; Dantrium; F 440; Sodium Dantrolene. Grades: Highly Purified. CAS No. 14663-23-1. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C??H?N?NaO?, Molecular Weight: 336.23. US Biological Life Sciences. | Worldwide |
| Dantrolene sodium salt hemiheptahydrate | Dantrolene sodium salt hemiheptahydrate. Group: Biochemicals. Alternative Names: 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione sodium salt hemiheptahydrate; Dantrium; Dantrolene sodium hemiheptahydrate. Grades: Highly Purified. CAS No. 24868-20-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C14H9N4NaO5·3.5H2O. US Biological Life Sciences. | Worldwide |
| Dantrolene, Sodium Salt Hemiheptahydrate (Dantrium, 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione) | A muscle relazant (sketal). Used in the treatment of malignant hyperthermia. Group: Biochemicals. Alternative Names: Dantrium, 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxy dantrolene | 5-Hydroxy dantrolene. Group: Biochemicals. Alternative Names: 5-Hydroxy-1- [ [ [5- (4-nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione. Grades: Highly Purified. CAS No. 52130-25-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C14H10N4O6. US Biological Life Sciences. | Worldwide |
| 5-Hydroxy Dantrolene | 5-Hydroxy Dantrolene is a metabolite of Dantrolene that has shown to have muscle relaxant effects. Synonyms: 5-Hydroxy-1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione. Grade: > 95%. CAS No. 52130-25-3. Molecular formula: C14H10N4O6. Mole weight: 330.25. | |
| 5-Hydroxydantrolene (2,4-Imidazolidinedione, 5-hydroxy-1- [ [ [5- (4-nitrophenyl) -2-furanyl] methylene] amino] ) | A metabolite of Dantrolene that has shown to have muscle relaxant effects. Group: Biochemicals. Alternative Names: 2,4-Imidazolidinedione, 5-hydroxy-1- [ [ [5- (4-nitrophenyl) -2-furanyl] methylene] amino] . Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxy Dantrolene-[d4] | 5-Hydroxy Dantrolene-[d4] is the labelled analogue of 5-Hydroxy Dantrolene, which is a metabolite of Dantrolene. Synonyms: 5-Hydroxy Dantrolene-d4; 5-Hydroxy-1-[[[5-(4-nitrophenyl-d4)-2-furanyl]methylene]amino]-2,4-imidazolidine-dione. Grade: ≥95%; ≥98% atom D. CAS No. 1217225-15-4. Molecular formula: C14H6D4N4O6. Mole weight: 334.28. | |
| 1-Amino-5-hydroxyhydantonin | 1-Amino-5-hydroxyhydantonin is an substituent in the synthesis of Dantrolene (D185000) metabolites shown to have muscle relaxant effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 42839-65-6. Pack Sizes: 25mg, 100mg. Molecular Formula: C3H5N3O3. US Biological Life Sciences. | Worldwide |
| 5-(3-Chlorophenyl)-2-furoic Acid | 5-(3-Chlorophenyl)-2-furoic acid is a reactant in the preparation of dantrolene which has a potential to treat vascular dysfunction. Synonyms: 5-(3-Chlorophenyl)-2-furancarboxylic Acid; 5-(3-Chlorophenyl)-2-furoic Acid; 5-(m-Chlorophenyl)-2-furancarboxylic Acid. Grade: 97%. CAS No. 41019-44-7. Molecular formula: C11H7ClO3. Mole weight: 222.62. | |
| Azumolene | Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene is a ryanodine receptor (RyR) modulator and inhibits the calcium-release through ryanodine receptor. Azumolene can be used for malignant hyperthermia research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EU4093 free base. CAS No. 64748-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113920A. | |
| Azumolene | Azumolene is a dantrolene derivative that acts as a ryanodine receptor (RyR) modulator. Azumolene blocks and reverses caffeine-induced contracture of human malignant hyperthermia susceptible skeletal muscle in vitro. Synonyms: EU4093 free base; Azumoleno; Azumolenum. CAS No. 64748-79-4. Molecular formula: C13H9BrN4O3. Mole weight: 349.14. | |
| Azumolene-[13C3] Sodium Salt | Azumolene-[13C3] Sodium Salt is the labelled analogue of Azumolene. Azumolene is an experimental drug which is a derivative of dantrolene. Synonyms: Azumolene-13C3 Sodium Salt. CAS No. 1391062-50-2. Molecular formula: C10[13C3]H8BrN4NaO3. Mole weight: 374.10. | |
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