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Dapsone Dapsone (4,4-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities [1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4,4-Diaminodiphenyl sulfone; DDS. CAS No. 80-08-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0688. MedChemExpress MCE
Dapsone Dapsone. Group: Biochemicals. Alternative Names: DADPS, DDS, avlosulfon, croysulfone, diphenasone, disulone, dumitone, eporal, novophone, sulfona-mae, sulphadione, 4, 4'-sulfonylbis Benzene amine; 1,1'-Sulfonylbis[4-aminobenzene]; 4,4'-Diaminodiphenyl sulfone. Grades: Highly Purified. CAS No. 80-08-0. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C12H12N2O2S. US Biological Life Sciences. USBiological 7
Worldwide
Dapsone-13C12 analytical standard. Group: Drugs & metabolites. Alfa Chemistry Analytical Products
Dapsone-[13C12] Dapsone-[13C12] is the labelled analogue of Dapsone. Dapsone is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. Synonyms: Dapsone-13C12; DADPS-13C12; DDS-13C12; Avlosulfon-13C12; Croysulfone-13C12; Diphenasone-13C12; Disulone-13C12; Dumitone-13C12; Sulphadione-13C12; 4,4'-Sulfonylbisbenzeneamine-13C12; 1,1'-Sulfonylbis[4-aminobenzene]-13C12; NSC 6091-13C12; 4,4'-Diaminodiphenyl-13C12-sulfone. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1632119-29-9. Molecular formula: [13C]12H12N2O2S. Mole weight: 260.21. BOC Sciences 2
Dapsone-15N2 Dapsone-15N2. Group: Biochemicals. Alternative Names: DADPS-15N2; DDS-15N2; Avlosulfon-15N2; Croysulfone-15N2; Diphenasone-15N2; Disulone-15N2; Dumitone-15N2; Eporal-15N2; Novophone-15N2; Sulfona-Mae-15N2; Sulphadione-15N2; 4, 4’-Sulfonylbis Benzene amine-15N2; 1,1'-Sulfonylbis[4-aminobenzene]-15N2; 4,4'-Diaminodiphenyl Sulfone; NSC 6091. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C12H1215N2O2S, Molecular Weight: 250.29. US Biological Life Sciences. USBiological 3
Worldwide
Dapsone-d4 A labeled antibacterial used in the treatment of dermatitis herpetiformis. Group: Biochemicals. Alternative Names: DADPS-d4, DDS-d4, Avlosulfon-d4, Croysulfone-d4, Diphenasone-d4, Disulone-d4, Dumitone-d4, Eporal-d4, Novophone-d4, Sulfona-Mae-d4, Sulphadione-d4, 4, 4’-Sulfonylbis Benzene amine-d4; 1,1'-Sulfonylbis[4-aminobenzene]-d4; 4,4'-Diaminodiphenyl Sulfone-d4; NSC 6091-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Dapsone-d4 Hydroxylamine (N-Hydroxy-4,4’-sulfonyldi(aniline)-d4) A labeled metabolite of Dapsone. Group: Biochemicals. Alternative Names: N-Hydroxy-4,4’-sulfonyldi(aniline)-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Dapsone-[d8] Dapsone-[d8] is the isotopically labelled Dapsone. Dapsone is an antibiotic used for the treatment of leprosy commonly in combination with rifampicin and clofazimine. Synonyms: Dapsone D8; 4,4'-Sulfonylbisbenzeneamine-D8; 4,4'-Sulfonylbis-benzen-2,3,5,6-d4-amine. Grade: 95% by HPLC; 95% atom D. CAS No. 557794-38-4. Molecular formula: C12H4D8N2O2S. Mole weight: 256.35. BOC Sciences 2
Dapsone (DADPS, DDS, Avlosulfon, Croysulfone, Diphenasone, Disulone, Dumitone, Eporal, NOvophone, Sulfona-Mae, Sulfadione, 4, 4’-Sulfonylbis Benzene amine) An antibacterial used in the treatment of dermatitis herpetiformis. Group: Biochemicals. Alternative Names: DADPS, DDS, Avlosulfon, Croysulfone, Diphenasone, Disulone, Dumitone, Eporal, NOvophone, Sulfona-Mae, Sulphadione, 4, 4’-Sulfonylbis Benzene amine. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. USBiological 1
Worldwide
Dapsone hydroxylamine Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDS-NOH. CAS No. 32695-27-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-137155. MedChemExpress MCE
Dapsone hydroxylamine Dapsone hydroxylamine. Group: Biochemicals. Alternative Names: N-Hydroxy-4,4'-sulfonyldi(aniline); N-Hydroxy-4,4'-sulfonyldi-aniline; 4-[(4-Aminophenyl)sulfonyl]-N-hydroxy-benzenamine. Grades: Highly Purified. CAS No. 32695-27-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H12N2O3S. US Biological Life Sciences. USBiological 7
Worldwide
Dapsone Hydroxylamine Dapsone Hydroxylamine is a metabolite of Dapsone. Synonyms: N-Hydroxy-4,4'-sulfonyldi(aniline); N-Hydroxy-4,4'-sulfonyldi-aniline; 4-[(4-Aminophenyl)sulfonyl]-N-hydroxy-benzenamine. Grade: > 95%. CAS No. 32695-27-5. Molecular formula: C12H12N2O3S. Mole weight: 264.3. BOC Sciences 7
Dapsone Hydroxylamine (N-Hydroxy-4,4’-sulfonyldi(aniline)) A metabolite of Dapsone. Group: Biochemicals. Alternative Names: N-Hydroxy-4,4’-sulfonyldi(aniline). Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
Dapsone Impurity 1 4-Chlorophenyl Phenyl Sulfone is an impurity of Dapson, an antibacterial used in the treatment of dermatitis herpetiformis. Synonyms: 4-Chlorophenyl Phenyl Sulfone; 4-Chlorodiphenyl Sulfone; 4-Chlorophenyl Phenyl Sulfone; NSC 404335; R 242; Sulfenon; Sulphenone; p-Chlorodiphenyl Sulfone; p-Chlorophenyl Phenyl Sulfone; p-Chlorophenyl Phenyl Sulfone; 1-Chloro-4-(phenylsulfonyl)benzene. Grade: > 95%. CAS No. 80-00-2. Molecular formula: C12H9ClO2S. Mole weight: 252.72. BOC Sciences 7
Dapsone Impurity 2 4-Amino-4'-chlorodiphenyl sulfone is a substituted 4-aminodiphenylsulfone as Escherichia coli dihydropteroate synthase inhibitor. Synonyms: 4-Amino-4'-chlorodiphenyl Sulfone; 4-[(4-Chlorophenyl)sulfonyl]benzenamine; p-[(p-Chlorophenyl)sulfonyl]aniline; 4-(4-Chlorobenzenesulfonyl)phenylamine; 4-Amino-4'-chlorodiphenyl Sulfone; 4-Aminophenyl 4-chlorophenyl Sulfone; NSC 23812; NSC 51990; p-(p-Ch. Grade: > 95%. CAS No. 7146-68-1. Molecular formula: C12H10ClNO2S. Mole weight: 267.73. BOC Sciences 7
Dapsone Impurity 3 4-Amino-4'-hydroxydiphenylsulfone is a diaryl sulfone with antileprotic activity. 4-Amino-4'-hydroxydiphenylsulfone is an antibacterial agent. Synonyms: 4-Amino-4'-hydroxydiphenylsulfone; 4-[(4-Aminophenyl)sulfonyl]phenol; p-Sulfanilylphenol. Grade: > 95%. CAS No. 25963-47-7. Molecular formula: C12H11NO3S. Mole weight: 249.29. BOC Sciences 7
Dapsone Impurity 4 4-Phenylsulfonylaniline is used in the preparation of novel Flufenamic acid analogues as inhibitors of androgen receptor mediated transcription. Synonyms: 4-Phenylsulfonylaniline; 4-(Phenylsulfonyl)benzenamine; p-(Phenylsulfonyl)aniline; 4-(Benzenesulfonyl)aniline; 4-(Benzenesulphonyl)phenylamine; 4-(Phenylsulfonyl)benzenamine; 4-Aminodiphenyl Sulfone; 4-Aminophenyl Phenyl Sulfone; 4-Phenylsulfonylaniline. Grade: > 95%. CAS No. 7019-1-4. Molecular formula: C12H11NO2S. Mole weight: 233.29. BOC Sciences 7
Dapsone Impurity 5 2,4'-Diaminophenyl Sulfone is used in biological studies as dapsone leprosy inhibitor. 2,4'-Diaminophenyl Sulfone is also an impurity of dapsone which is an antibacterial used in the treatment of dermatitis herpetiformis. Synonyms: 2,4'-Diaminophenyl Sulfone; 2,4'-Sulfonyldi-aniline; 2,4'-Diaminodiphenyl Sulfone; 2,4'-Diaminophenyl Sulfone; 4,2'-Bis(aminophenyl) Sulfone; 2-[(4-Aminophenyl)sulfonyl]-benzenamine. Grade: > 95%. CAS No. 27147-69-9. Molecular formula: C12H12N2O2S. Mole weight: 248.3. BOC Sciences 7
Dapsone Lactose Adduct A metabolite of Dapsone, which is a synthetic sulfone compound with antimicrobial and anti-inflammatory properties. Dapsone is primarily used to treat Mycobacterium leprae infections (leprosy) and Pneumocystis jirovecii pneumonia, often as part of combination therapy. Dapsone inhibits dihydropteroate synthase, an enzyme involved in folic acid synthesis, thereby interfering with bacterial growth. Grade: ≥95%. Molecular formula: C24H32N2O12S : C24H32N2O12S. Mole weight: 572.58 : 572.58. BOC Sciences 7
4,4'-Diaminodiphenyl sulfone (Dapsone) 500g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Building Blocks, Research Organics & Inorganics. Formula: [4-(NH2)C6H4]2SO2. CAS No. 80-08-0. Prepack ID 28069836-500g. Molecular Weight 248.3. See USA prepack pricing. Molekula Americas
N-Acetyl dapsone N-Acetyl dapsone. Group: Biochemicals. Alternative Names: N-[4-[ (4-Aminophenyl) sulfonyl]phenyl]-acetamide; Acetyldapsone; MADDS. Grades: Highly Purified. CAS No. 565-20-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C14H14N2O3S. US Biological Life Sciences. USBiological 6
Worldwide
N-Acetyl dapsone-d4 N-acetyl Dapsone-d 4 is the deuterium labeled N-acetyl Dapsone, which is a metabolite of Dapsone. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: MADDS-d4; Monoacetyldapsone-d4. CAS No. 2070015-08-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-G0016S. MedChemExpress MCE
N-Acetyl Dapsone-[d4] N-Acetyl Dapsone-[d4] is the labelled analogue of N-Acetyl Dapsone, which is a metabolite of Dapsone. Dapsone is an antibiotic used in combination with rifampicin and clofazimine for the treatment of leprosy. Synonyms: N-Acetyl Dapsone D4; N-[4-[(4-Aminophenyl)sulfonyl]phenyl]-acetamide-D4; Acetyldapsone-D4; MADDS-D4; Monoacetyldapsone-D4. Grade: ≥95%. CAS No. 2070015-08-4. Molecular formula: C14H10D4N2O3S. Mole weight: 294.36. BOC Sciences 2
2,4'-Diaminophenyl Sulfone 2,4'-Diaminophenyl Sulfone is used in biological studies as dapsone leprosy inhibitor. 2,4'-Diaminophenyl Sulfone is also an impurity of dapsone (D193250) which is an antibacterial used in the treatment of dermatitis herpetiformis. Group: Biochemicals. Grades: Highly Purified. CAS No. 27147-69-9. Pack Sizes: 100mg, 1g. Molecular Formula: C12H12N2O2S, Molecular Weight: 248.3. US Biological Life Sciences. USBiological 10
Worldwide
2,4'-Diaminophenyl Sulfone-d4 2,4'-Diaminophenyl Sulfone-d4 is the isotope analog of 2,4'-Diaminophenyl Sulfone. 2,4'-Diaminophenyl Sulfone is used in biological studies as dapsone leprosy inhibitor. 2,4'-Diaminophenyl Sulfone is also an impurity of dapsone (D193250) which is an antibacterial used in the treatment of dermatitis herpetiformis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10g. Molecular Formula: C12H8D4N2O2S, Molecular Weight: 252.33. US Biological Life Sciences. USBiological 10
Worldwide
4-(4-Aminophenyl)sulfonylaniline;5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine 4-(4-Aminophenyl)sulfonylaniline;5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Folaprim, Deltaprim, Maloprim, Maloprime, Dapsone & Pyrimethamine, Dapsone mixture with pyrimethamine, AIDS029730, AIDS-029730, CID65405, 2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-, mixt. with 4,4-sulfonylbis(benzenamine), 37357-69-0. Product Category: Heterocyclic Organic Compound. CAS No. 37357-69-0. Molecular formula: C24H25ClN6O2S. Mole weight: 497.012 g/mol. Purity: 0.96. IUPACName: 4-(4-aminophenyl)sulfonylaniline; 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine. Canonical SMILES: CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl.C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N. Product ID: ACM37357690. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
4,4'-Diaminodiphenylsulfone Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase. Uses: Anti-inflammatory agent. Synonyms: 4-(4-aminophenyl)sulfonylaniline. Grade: > 98 %. CAS No. 80-08-0. Molecular formula: C12H12N2O2S. Mole weight: 248.30. BOC Sciences 2
4,4'-Di-N-acetylamino-diphenylsulfone-[d8] 4,4'-Di-N-acetylamino-diphenylsulfone-[d8] is the labelled analogue of 4,4'-Di-N-acetylamino-diphenylsulfone. It has antimicrobial and antimalarial effects, but is mainly used as a depot leprostatic agent. Uses: Isotopically labelled intermediate of dapsone. Synonyms: 4,4'-Di-N-acetylamino-diphenylsulfone D8; N,N'-[Sulfonyldi(4,1-phenylene-2,3,5,6-d4)]bis-acetamide; Acedapsone-d8; Hansolar-d8; Diacetyldapsone-d8; Sulfadiamine-d8; Rodilone-d8; Camilan-d8; p,p'-Sulfonylbisacetanilide-d8; N,N'-Diacetyldapsone-d8; Bis(p-acetamidophenyl)sulfone-d8; Di(p-acetylaminophenyl)sulfone-d8. Grade: ≥98%; ≥97% atom D. CAS No. 557794-37-3. Molecular formula: C16H8D8N2O4S. Mole weight: 340.42. BOC Sciences 2
4,4’-Di-N-acetylamino-diphenylsulfone-d8 Isotopically labeled intermediate of Dapsone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
Worldwide
4,4'-Di-N-acetylamino-diphenylsulfoxide-[d8] 4,4'-Di-N-acetylamino-diphenylsulfoxide-[d8]. Uses: Isotopically labelled intermediate of dapsone. Synonyms: 4,4'-Di-N-acetylamino-diphenylsulfoxide D8; N,N'-[Sulfinyldi(4,1-phenylene-2,3,5,6-d4)]bis-acetamide; N-[4-(4-acetamidophenyl)sulfinylphenyl]acetamide-d8; Bis[4-acetamidophenyl]sulfoxide-d8. Grade: ≥98%; ≥97% atom D. CAS No. 557794-36-2. Molecular formula: C16H8D8N2O3S. Mole weight: 324.42. BOC Sciences 2
4,4’-Di-N-acetylamino-diphenylsulfoxide-d8 Isotopically labeled intermediate of Dapsone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
4-amino-5-(4-chlorophenyl)-6-ethyl-1H-pyrimidin-2-one An impurity of Pyrimethamine. Pyrimethamine can be used with leucovorin to treat toxoplasmosis and cystoisosporiasis. It is also used with dapsone as a second line option to prevent Pneumocystis jiroveci pneumonia in people with HIV/AIDS. Synonyms: Cytosine, 5-(p-chlorophenyl)-6-ethyl-2(1H)-Pyrimidinone, 6-amino-5-(4-chlorophenyl)-4-ethyl-. Grade: 98% by HPLC. CAS No. 93456-61-2. Molecular formula: C12H12ClN3O. Mole weight: 249.69. BOC Sciences 4
4-Nitro-4’-acetylaminodiphenyl-d4 Sulfone Labeled Dapsone intermediate. Group: Biochemicals. Alternative Names: N- [4- [ (4-Nitrophenyl) sulfonyl] phenyl] acetamide-d4; 4'-[ (p-Nitrophenyl) sulfonyl]acetanilide-d4; 4-Acetamido-4'-nitrodiphenyl-d4 Sulfone; NSC 30177-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Clofazimine-[d7] Clofazimine-[d7] is a labelled Clofazimine. Clofazimine is used for the treatment of multibacillary leprosy in combination with rifampicin and dapsone. Synonyms: N,5-Bis(4-chlorophenyl)-3-((propan-2-yl-d7)imino)-3,5-dihydrophenazin-2-amine; Clofazimine D7; N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl-d7)imino]-2-phenazinamine; 3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino-d7)phenazine; 2-(4-Chloroanilino)-3-(isopropyl-d7)imino-5-(4-chlorophenyl)-3,5-dihydrophenazine; Chlofazimine-d7; Hansepran-d7; Lamprene-d7. Grade: >95%. Molecular formula: C27H15D7Cl2N4. Mole weight: 480.44. BOC Sciences 2
Pyrimethamine-[d3] Pyrimethamine-[d3] is the labelled analogue of Pyrimethamine. Pyrimethamine can be used with leucovorin to treat toxoplasmosis and cystoisosporiasis. It is also used with dapsone as a second line option to prevent Pneumocystis jiroveci pneumonia in people with HIV/AIDS. Synonyms: Pyrimethamine D3; 5-(4-Chlorophenyl)-6-ethyl-d3-2,4-pyrimidinediamine; 2,4-Diamino-5-(4-chlorophenyl)-6-ethyl-d3-pyrimidine; Chloridin-d3. Grade: 95% by HPLC; 95% atom D. CAS No. 1189936-99-9. Molecular formula: C12H10D3ClN4. Mole weight: 251.73. BOC Sciences 2

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