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| Product | Description | |
|---|---|---|
| DAPT | Cell permeable gamma-secretase inhibitor (IC50 = 115nM for total beta-amyloid, IC50 = 200nM for beta-amyloid 1-42). Reduces Abeta levels in vivo. Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD). Does not inhibit persenilinase. Notch processing inhibitor. Enhances neuronal differentiation independent of sonic hedgehog (Shh) signaling. CDK5 activity inhibitor. Apoptosis enhancer. Group: Biochemicals. Alternative Names: (S)-Tert-butyl 2- ( (S) -2- (2- (3, 5-difluorophenyl) acetamido) propanamido) -2-phenylacetate; N-S-phenylglycine tert.butyl ester; GSI-IX; Secretase, gamma Inhibitor IX. Grades: Highly Purified. CAS No. 208255-80-5. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. |  Worldwide |
| DAPT | DAPT, also called γ-Secretase Inhibitor IX, is a potent and selective inhibitor of γ-secretase which leads to a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human)). Uses: Differentiation. Synonyms: tert-butyl (2S) -2-[[ (2S) -2-[[2- (3, 5-difluorophenyl) acetyl]amino]propanoyl]amino]-2-phenylacetate; dapt; 208255-80-5; DAPT (GSI-IX); gamma-Secretase Inhibitor IX; CHEBI:86193; MFCD04974585; DAPT, GSI-IX; InSolution gamma-Secretase Inhibitor IX; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester(DAPT); C23H26F2N2O4; GSIIX; S2215_Selleck; AC1NSKCB; PubChem22436; GSI-IX; DAPT,GSI-IX; DAPT; DAPT - GSI-IX; MLS006010075; CHEMBL255682; QCR-29; SCHEMBL1360313; DTXSID00415519; AOB33372; DAPT-Supplied by Selleck Chemicals; EBD16444; ZINC1549363; ABP000317; ZINC01549363; AKOS024457209; CS-0264; NCGC00167803-03; (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu; AC-23163; AK477268; BC649954; CJ-24363; HY-13027; KB-57235; SMR004701228; AB0033805; LS-191073; D4257; GSI-IX, 208255-80-5; X7572; W-5319; AB01566837_01; GSI-IX , GSI IX; 208255-80-5; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester; DAPT|N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[(3,5-Difluorophenyl)acetyl]-[l-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester. Grades: 0.98. CAS No. 208255-80-5. Molecular formula: C23H26F2N2O4. Mole weight: 432.46. |  |
| DAPT | DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC 50 s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ 42 , respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSI-IX. CAS No. 208255-80-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13027. |  |
| DAPT | DAPT Inhibitor. Uses: Scientific use. Product Category: T6202. CAS No. 208255-80-5. |  |
| DAPTA | DAPTA. Group: Biochemicals. Grades: Purified. CAS No. 106362-34-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| DAPTA | DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5 , and shows potent anti-HIV activities. Uses: Scientific research. Group: Peptides. Alternative Names: D-Ala-peptide T-amide; Adaptavir. CAS No. 106362-34-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1034. | |
| Daptomycin | 100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C72H101N17O26. CAS No. 103060-53-3. Prepack ID 64342447-100mg. Molecular Weight 1620.67. See USA prepack pricing. |  |
| Daptomycin | Daptomycin is a lipopeptide antibiotic produced by the soil saprotroph Streptomyces roseosporus. It is used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Uses: Anti-bacterial agents. Synonyms: LY 146032; LY-146032; LY146032; Daptomycin; Cidecin; Cubicin; (2S)-daptomycin. Grades: >95%. CAS No. 103060-53-3. Molecular formula: C72H101N17O26. Mole weight: 1620.69. | |
| Daptomycin | Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms. Uses: Scientific research. Group: Peptides. Alternative Names: LY146032. CAS No. 103060-53-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0108. | |
| Daptomycin impurity 1 | Daptomycin impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C44H66N10O15. Mole Weight: 975.07. Catalog: APB11224. |  |
| Daptomycin Impurity-1 | Daptomycin Impurity-1 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Daptomycin Impurity B1/2; N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornathyl-L-aspartic acid. Molecular formula: C44H66N10O15. Mole weight: 975.07. | |
| Daptomycin Impurity 10 | Daptomycin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5S,11S,14S)-14-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-5-(3-aminopropyl)-11-((R)-1-hydroxyethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane-1,2,15-tricarboxylic acid. Molecular Formula: C44H66N10O15. Mole Weight: 975.05. Catalog: APB05223. | |
| Daptomycin Impurity 11 | Daptomycin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,5S,8S,14S,15R,18S,21S,22S)-14-((S)-2-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-21-((R)-2-(2-aminoacetamido)-3-hydroxypropanamido)-18-(2-(2-aminophenyl)-2-oxoethyl)-8-(3-aminopropyl)-5-(carboxymethyl)-2,15,22-trimethyl-4,7,10,13,17,20-hexaoxo-16-oxa-3,6,9,12,19-pentaazatetracosane-1,24-dioic acid. Molecular Formula: C68H98N16O24. Mole Weight: 1523.60. Catalog: APB05221. | |
| Daptomycin Impurity 12 | Daptomycin Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-((3S,6S,9R,15S,18R,21S,24S,30S,31R)-30-((S)-2-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-((S)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontane-15,21-diyl)diacetic acid. Molecular Formula: C72H101N17O26. Mole Weight: 1620.67. Catalog: APB05219. | |
| Daptomycin Impurity 13 | Daptomycin Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-(30-(2-(2-(3-(1H-indol-3-yl)-2-undecanamidopropanamido)-4-amino-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-(1-carboxypropan-2-yl)-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontane-15,21-diyl)diacetic acid. Molecular Formula: C73H103N17O26. Mole Weight: 1634.70. Catalog: APB05220. | |
| Daptomycin impurity 14 | Daptomycin impurity 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C72H99N17O25. Mole Weight: 1602.68. Catalog: APB11246. | |
| Daptomycin Impurity 14 | Daptomycin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5S,8R,14S,17R,20S,23S,29S,32S)-32-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-2-(2-(2-aminophenyl)-2-oxoethyl)-23-(3-aminopropyl)-14,20-bis(carboxymethyl)-5-((R)-1-carboxypropan-2-yl)-29-((R)-1-hydroxyethyl)-8-(hydroxymethyl)-17-methyl-4,7,10,13,16,19,22,25,28,31-decaoxo-3,6,9,12,15,18,21,24,27,30-decaazatetratriacontane-1,34-dioic acid. CAS No. 883991-21-7. Molecular Formula: C72H103N17O27. Mole Weight: 1638.69. Catalog: APB883991217. | |
| Daptomycin impurity 15 | Daptomycin impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C74H107N17O27. Mole Weight: 166.76. Catalog: APB11245. | |
| Daptomycin impurity 16 | Daptomycin impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C72H103N17O27. Mole Weight: 1638.71. Catalog: APB11244. | |
| Daptomycin Impurity 17 | Daptomycin Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-((3S,6S,9R,15R,18R,21S,24S,30S,31R)-30-((S)-2-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-((S)-1-carboxypropan-2-yl)-18-ethyl-9-(hydroxymethyl)-31-methyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontane-15,21-diyl)diacetic acid. Molecular Formula: C73H103N17O26. Mole Weight: 1634.70. Catalog: APB05218. | |
| Daptomycin Impurity 18 | Daptomycin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,8S,11S,14R,17S)-17-((1H-indol-3-yl)methyl)-14-(2-amino-2-oxoethyl)-2-(3-aminopropyl)-11-(carboxymethyl)-8-((R)-1-hydroxyethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazaoctacosan-1-oic acid. Molecular Formula: C40H61N9O12. Mole Weight: 859.97. Catalog: APB05217. | |
| Daptomycin Impurity 19 | Daptomycin Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S)-3-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-4-(((5R, 8S, 11S, 14R, 15S, 21S, 24S, 27R, 30S)-11-(2-(2-aminophenyl)-2-oxoethyl)-21-(3-aminopropyl)-24-(carboxymethyl)-8-((S)-1-carboxypropan-2-yl)-5-(hydroxymethyl)-14, 27-dimethyl-3, 6, 9, 12, 16, 19, 22, 25, 28, 32, 33-undecaoxo-13-oxa-1, 4, 7, 10, 17, 20, 23, 26, 29-nonaazabicyclo[28.2.1]tritriacontan-15-yl)amino)-4-oxobutanoic acid. Molecular Formula: C72H99N17O25. Mole Weight: 1602.66. Catalog: APB05216. | |
| Daptomycin impurity 2 | Daptomycin impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C40H61N9O12. Mole Weight: 859.98. Catalog: APB11243. | |
| Daptomycin impurity 20 | Daptomycin impurity 20. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C72H103N17O27. Mole Weight: 1638.71. Catalog: APB11247. | |
| Daptomycin impurity 21 | Daptomycin impurity 21. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C72H101N17O27. Mole Weight: 1636.69. Catalog: APB11248. | |
| Daptomycin impurity 22 | Daptomycin impurity 22. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C72H99N17O25. Mole Weight: 1602.68. Catalog: APB11249. | |
| Daptomycin impurity 23 | Daptomycin impurity 23. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C71H100N16O25. Mole Weight: 1577.67. Catalog: APB11250. | |
| Daptomycin impurity 24 | Daptomycin impurity 24. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C73H103N17O26. Mole Weight: 1634.72. Catalog: APB11251. | |
| Daptomycin impurity 3 | Daptomycin impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C74H103N17O27. Mole Weight: 1662.73. Catalog: APB11242. | |
| Daptomycin Impurity-3 | Daptomycin Impurity-3 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ser-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); 8-D-Serinedaptomycin; Daptomycin, 8-D-serine-. CAS No. 921590-20-7. Molecular formula: C72H101N17O27. Mole weight: 1636.69. | |
| Daptomycin Impurity 4 | Daptomycin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5R,15S,18S,21S,27S)-11-((S)-2-((S)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-15-(2-(2-aminophenyl)-2-oxoethyl)-27-((R)-2-aminopropanamido)-5-(3-aminopropyl)-18-((S)-1-carboxypropan-2-yl)-21-(hydro. Molecular Formula: C72H103N17O27. Mole Weight: 1638.69. Catalog: APB05226. | |
| Daptomycin Impurity 5 | Daptomycin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6R,15S)-15-((S)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-6-(3-aminopropyl)-12-(1-hydroxyethyl)-3-(hydroxymethyl)-5,8,11,14-tetraoxo-4,7,10,13-tetraazaheptadecane-1,17-dioic acid. Molecular Formula: C44H68N10O14. Mole Weight: 961.07. Catalog: APB05225. | |
| Daptomycin Impurity 6 | Daptomycin Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S)-3-((S)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-4-(((2R,5S,11S,14S,17S,27R)-17-(2-(2-aminophenyl)-2-oxoethyl)-27-(3-aminopropyl)-5-(carboxymethyl)-14-((S)-1-carboxypropan-2-yl)-11-(hydroxymethyl)-2,20-dimethyl-3,6,9. Molecular Formula: C72H99N17O25. Mole Weight: 1602.66. Catalog: APB05224. | |
| Daptomycin Impurity-6 | Daptomycin Impurity-6 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-Ser-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin RS-6; 8-L-Serinedaptomycin. Molecular formula: C72H101N17O27. Mole weight: 1636.69. | |
| Daptomycin Impurity 7 | Daptomycin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,12S,15S,18S,24S,27R,30S)-30-amino-8-((S)-2-((S)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-12-(2-(2-aminophenyl)-2-oxoethyl)-2-(3-aminopropyl)-24-(carboxymethyl)-15-((S)-1-carboxypropan-2-yl)-18-(h. Molecular Formula: C72H103N17O27. Mole Weight: 1638.69. Catalog: APB05222. | |
| Daptomycin Impurity-7 | Daptomycin Impurity-7 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-Abu-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin RS-7; 8-L-2-Aminobutyric acid-daptomycin. Molecular formula: C73H103N17O26. Mole weight: 1634.72. | |
| Daptomycin Impurity 8 | Daptomycin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S)-3-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-4-(((5R, 8S, 11S, 14R, 15S, 21S, 24S, 27R, 30R)-11-(2-(2-aminophenyl)-2-oxoethyl)-21-(3-aminopropyl)-24-(carboxymethyl)-8-((R)-1-carboxypropan-2-yl)-5-(hydroxymethyl)-14, 27-dimethyl-3, 6, 9, 12, 16, 19, 22, 25, 28, 32, 33-undecaoxo-13-oxa-1, 4, 7, 10, 17, 20, 23, 26, 29-nonaazabicyclo[28.2.1]tritriacontan-15-yl)amino)-4-oxobutanoic acid. Molecular Formula: C72H99N17O25. Mole Weight: 1602.66. Catalog: APB01905. | |
| Daptomycin Impurity-8 | Daptomycin Impurity-8 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-3Me-Glu-Phe-OH (ε1-lactone); Daptomycin RS-8; Daptomycin impurity-35; N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-L-Phenylalanine (ε1-lactone). Molecular formula: C71H100N16O25. Mole weight: 1577.67. | |
| Daptomycin Impurity 9 | Daptomycin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5S,11S,14S)-14-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-5-(3-aminopropyl)-11-((R)-1-hydroxyethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane-1,2,15-tricarboxylic acid. Molecular Formula: C44H66N10O15. Mole Weight: 975.05. Catalog: APB01904. | |
| Daptomycin Impurity B1-I | Daptomycin Impurity B1-1 is an impurity of Daptomycin (D193350), cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C44H66N10O15; (C2HF3O2). US Biological Life Sciences. | Worldwide |
| Daptomycin Impurity-B1/II | Daptomycin Impurity-B1/II is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithine-L-aspartyl-D-alanine. Molecular formula: C47H71N11O16. Mole weight: 1046.15. | |
| Daptomycin Impurity-B2 | Daptomycin Impurity-B2 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithine; L-Ornithine, N-(1-oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-. CAS No. 866822-35-7. Molecular formula: C40H61N9O12. Mole weight: 859.98. | |
| Daptomycin Impurity B2 Trifluoroacetic Acid Salt | Daptomycin Impurity B2 Trifluoroacetic Acid Salt. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS007326. Format: Neat. Shipping: Room Temperature. | |
| Daptomycin Impurity beta-Isomer | Daptomycin Impurity beta-Isomer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S,6S,9S,19R,22S,25R)-31-((S)-2-((S)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-25-(3-aminopropyl)-22-(carboxymethyl)-6-((S)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-19. CAS No. 123180-72-3. Molecular Formula: C72H101N17O26. Mole Weight: 1620.67. Catalog: APB123180723. | |
| Daptomycin Impurity RS-7b | Daptomycin Impurity RS-7b is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryprophyl-D-asparginyl-L-aspartyl-L-threonyl (L-aspartyl-D-alanyl-L-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine ε1-lactone)glycyl-L-ornathine; N-dec-Trp-D-Asn-Asp-Thr-Gly-Orn-OH-Asp-D-Ala-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone). Molecular formula: C72H103N17O27. Mole weight: 1638.71. | |
| Daptomycin Isodecy acyl isomer | Daptomycin Isodecy acyl isomer is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Isodecylacyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin impurity-32; 1-[N-(8-Methyl-1-oxononyl)-L-tryptophan]daptomycin; Daptomycin, 1-[N-(8-methyl-1-oxononyl)-L-tryptophan]-; N-(8-Methylnonanoyl)-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxy-2-propanyl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]-L-α-asparagine. CAS No. 1233389-15-5. Molecular formula: C72H101N17O26. Mole weight: 1620.69. | |
| Daptomycin (Ly-146032, Cidecin, Cubicin) | Daptomycin is a member of the Antibiotic A 21978 complex of high molecular weight cyclic lipopeptides with potent antibiotic activity, notably against MRSA, VISA and VRSA resistant bacteria. Originally isolated from Streptomyces roseosprous by Eli Lily in the 1980s, daptomycin was selected and developed by Cubist Pharmaceticals for human use. Daptomycin exhibits Ca-dependent depolarisation of the bacterial membrane resulting in loss of membrane potential leading to inhibition of DNA, RNA and protein synthesis which results in cell death. Group: Biochemicals. Alternative Names: Ly-146032; Cidecin; Cubicin. Grades: Highly Purified. CAS No. 103060-53-3. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Daptomycin (RS-1) | Daptomycin (RS-1) is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Daptomycin Impurity-1. Molecular formula: C72H103N17O27. Mole weight: 1638.71. | |
| Daptomycin RS-4 | Daptomycin RS-4 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: 3-OH-Dodecanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin Impurity-4; Benzenebutanoic acid, N-(3-hydroxy-1-oxododecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-, (13?4)-lactone, (αS)-. Molecular formula: C74H105N17O27. Mole weight: 1664.75. | |
| Daptomycin RS-5 | Daptomycin RS-5 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-glycyl-L-asprtyl-glycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine (ε1-lactone); Daptomycin RS-5; Daptomycin Impurity-5. Molecular formula: C71H99N17O26. Mole weight: 1606.67. | |
| 9-(2,5-d|Dioxo-L-3-amino-1-pyrrolidineacetic acid)-10-deglycine Daptomycin | Cas No. 121869-35-0. | |
| 9-L-β-Aspartic acid-daptomycin | 9-L-β-Aspartic acid-daptomycin is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Daptomycn β-Isomer; Daptomycin, 9-L-β-aspartic acid-; CB 131010; LY 213846; N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-β-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-(αS)-α,2-diamino-γ-oxobenzenebutanoic acid (13?4)-lactone; N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-β-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine (ε1-lactone). Grades: ≥95%. CAS No. 123180-72-3. Molecular formula: C72H101N17O26. Mole weight: 1620.67. | |
| Adaptavir | A CCR5 receptor antagonist. CCR5 antagonists block HIV from getting into and infecting certain cells of the immune system. Synonyms: RAP-101; D-Ala-1-peptide T-NH-2; DAPTA; mDAPTA; Monomeric (D-Alanine-1) Peptide T amide. Grades: >98% (or refer to the Certificate of Analysis). CAS No. 106362-34-9. Molecular formula: C35H56N10O15. Mole weight: 856.89. | |
| Kyn1-(Des-Trp1) Daptomycin | Kyn1-(Des-Trp1) Daptomycin is a derivative of Daptomycin (D193350), is a cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C71H101N17O27, Molecular Weight: 1624.66. US Biological Life Sciences. | Worldwide |
| Linear Daptomycin | Daptomycin Lactone Hydrolysis is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine; decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-Glu(3R-Me)-Asp(Ph(2-NH2))-OH; (2S,5S,8R,14S,17R,20S,23S,29S,32S)-32-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-2-(2-(2-aminophenyl)-2-oxoethyl)-23-(3-aminopropyl)-14,20-bis(carboxymethyl)-5-((R)-1-carboxypropan-2-yl)-29-((R)-1-hydroxyethyl)-8-(hydroxymethyl)-17-methyl-4,7,10,13,16,19,22,25,28,31-decaoxo-3,6,9,12,15,18,21,24,27,30-decaazatetratriacontanedioic acid; Benzenebutanoic acid, N-(1-oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-, (αS)-; (αS)-N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxobenzenebutanoic acid; Daptomycin Lactone Hydrolysis. CAS No. 883991-21-7. Molecular formula: C72H103N17O27. Mole weight: 1638.71. | |
| AFN-1252 | AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomycin and resulted in sustained bacterial killing. In turn, daptomycin prevented the fatty acid-dependent emergence of AFN-1252-resistant isolates in vitro. Group: Inhibitors. Alternative Names: AFN-1252; AFN 1252; AFN1252; API-1252; API1252; API 1252; AFN12520000; AFN 12520000; AFN12520000; Debio1452; Debio 1452; Debio1452. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide. Canonical SMILES: O=C (N (C)CC1=C (C)C2=CC=CC=C2O1)/C=C/C3=CC (CC4)=C (N=C3)NC4=O. Catalog: ACM620175395. |  |
| KKL-40 | KKL-40 is a small molecule inhibitor that targets the trans-transcription process and is effective against methicillin-sensitive and -resistant Staphylococcus aureus (S. aureus) as well as other Gram-positive pathogens including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. KKL-40 synergizes with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not synergize with other antibiotics such as daptomycin, kanamycin, or erythromycin. Trans-transcription is an extreme form of recoding, and KKL-40 inhibits trans-transcription but is nontoxic to HeLa cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865285-47-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116863. | |
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