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Daunorubicin Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-;Daunomycin. Product Category: Inhibitors. CAS No. 20830-81-3. Molecular formula: C27H29NO10. Mole weight: 527.52. Product ID: ACM20830813. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Daunorubicin-[13C,d3] Daunorubicin-[13C,d3], is the labelled analogue of Daunorubicin. Daunorubicin is used for acute myeloid leukemia, acute lymphocytic leukemia, chronic myelogenous leukemia, and Kaposi's sarcoma. Synonyms: Daunorubicin 13CD3; (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione-3C,d3. Grades: 85% (CP); 98% atom D; 98% atom 13C. Molecular formula: C26[13C]H26D3NO10. Mole weight: 531.53. BOC Sciences
Daunorubicin-13C,d3 Daunorubicin-13C,d3. Group: Biochemicals. Alternative Names: (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione-13C,d3. Grades: Purified. CAS No. 20830-81-3 unlabeled. Pack Sizes: 250ug. Molecular Formula: C2613CH26D3NO10, Molecular Weight: 531.53. US Biological Life Sciences. USBiological 1
Worldwide
Daunorubicin 4'-O-α-D-Glucoside Sodium Salt Daunorubicin 4'-O-α-D-glucoside is a derivative of Daunorubicin. Daunorubicin is an anticancer drug that is often used in conjunction with other cytotoxic agents to treat various types of leukemias and carcinomas. Daunorubicin also provides a positive outlook for patients with acute promyelocytic leukemia, inducing remission in about half of the patients. Synonyms: (2S,3S,4S,5R,6S)-6-(((2S,3S,4S,6R)-6-(((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-4-amino-2-methyltetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate sodium salt; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-4-O-α-D-glucopyranuronosyl-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Monosodium Salt. CAS No. 229314-76-5. Molecular formula: C33H36NNaO16. Mole weight: 725.63. BOC Sciences 12
Daunorubicin-d3 Daunorubicin-d3 , a meticulously stable isotope-enriched rendition of Daunorubicin, is an esteemed anthracycline antibiotic extensively employed in the research of diverse cancer modalities, encompassing acute myeloid leukemia, lymphomas and solid tumors. Molecular formula: C27H26D3NO10. Mole weight: 530.54. BOC Sciences 11
Daunorubicin EP Impurity B Daunorubicinol, a metabolite of Daunorubicin, is an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Synonyms: 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-((1S)-1-hydroxyethyl)-1-methoxy-, (8S,10S)-; 13-Dihydrodaunorubicin; Duborimycin; Leukaemomycin D; Daunorubicin EP Impurity B (Mixture of Diastereomers); (13S)-13-Dihydrodaunorubicin; (1S,3S)-3,5,12-Trihydroxy-3-[(1S)-1-hydroxyethyl]-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; Daunomycinol; Dihydrodaunomycin; Antibiotic 20-798RP; Daunorubicinol. Grades: >95%. CAS No. 28008-55-1. Molecular formula: C27H31NO10. Mole weight: 529.54. BOC Sciences 9
Daunorubicin EP Impurity C (Feudomycin B) Feudomycin B, an impurity of Daunorubicin, is an anthracycline antibiotic isolated from Streptomyces coeruleorubidus. Feudomycin B is used as an antitumor agent. Synonyms: (8S,10S)-10-[(3-amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-1-methoxy-8-(2-oxopropyl)-7,8,9,10-tetrahydrotetracene-5,12-dione; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopy ranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-8-(2-oxop ropyl)-, (8S-cis)-; (8S)-10α-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8α,11-trihydroxy-1-methoxy-8β-(2-oxopropyl)-5,12-naphthacenedione; Daunorubicin Impurity 3; (1S,3S)-3,5,12-Trihydroxy-10-methoxy-6,11-dioxo-3-(2-oxopropyl)-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside. Grades: ≥95%. CAS No. 79438-97-4. Molecular formula: C28H31NO10. Mole weight: 541.55. BOC Sciences 6
Daunorubicin EP Impurity D (Doxorubicin) Doxorubicin is an anthracycline antibiotic produced in Str. peucetius var. caesinus. Doxorubicin has anti-Gram-positive bacteria activity and has a broad anti-tumor spectrum. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Uses: Adcs cytotoxin. Synonyms: (8S,10S)-10-[(3-amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Adriamycin; Doxil; Adriablastin; Doxorubicine; Adriblastina; 14-Hydroxydaunomycin; 14-Hydroxydaunorubicine; Caelyx; Hydroxydaunorubicin; NSC-759155; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-; NSC-123127; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside; Epirubicin EP Impurity C. Grades: >98%. CAS No. 23214-92-8. Molecular formula: C27H29NO11. Mole weight: 543.52. BOC Sciences 6
Daunorubicin HCl anti-neoplastic LD50 in mice 26 mg/kg. CAS No. 23541-50-6. Product ID: 1-00926. Molecular formula: C27H29NO10 HCl. Mole weight: 563.99. Purity: >95%. Properties: [a]D20 250-275 (c = 0.15, MeOH), >900 mg/mg. Source : Reference: Cancer Chemother. Rep., 53, 33, 1969. CarboMer Inc
Daunorubicin HCl EP Impurity F Cas No. 771423-67-7. BOC Sciences 8
Daunorubicin hydrochloride 10mg Pack Size. Group: Antibiotics, Research Organics & Inorganics. Formula: C27H29NO10 · HCl. CAS No. 23541-50-6. Prepack ID 11269897-10mg. Molecular Weight 563.98. See USA prepack pricing. Molekula Americas
Daunorubicin hydrochloride 25mg Pack Size. Group: Antibiotics, Research Organics & Inorganics. Formula: C27H29NO10 · HCl. CAS No. 23541-50-6. Prepack ID 11269897-25mg. Molecular Weight 563.98. See USA prepack pricing. Molekula Americas
Daunorubicin hydrochloride Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor [1] [2] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride. CAS No. 23541-50-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13062. MedChemExpress MCE
Daunorubicin hydrochloride Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. Uses: Adcs cytotoxin. Synonyms: RP 13057 Hydrochloride; Daunomycin; RP13057 Hydrochloride; RP-13057 Hydrochloride; Rubidomycin hydrochloride. Grades: >98%. CAS No. 23541-50-6. Molecular formula: C27H30ClNO10. Mole weight: 563.98. BOC Sciences
Daunorubicin hydrochloride meets USP testing specifications. Group: Fluorescence/luminescence spectroscopyapi standardscarbohydrateschiral moleculeseuropean pharmacopoeia (ph. eur.)impurity standardspharmaceutical toxicologypharmacopoeial standards. Alternative Names: Epirubicin Hydrochloride Imp. D (EP), Daunorubicin hydrochloride, (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-l-lyxo-hexopyranosyl)oxy]-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride, Epirubicin Imp. D (EP). Alfa Chemistry Analytical Products
Daunorubicin hydrochloride United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Daunorubicin, Hydrochloride - CAS 23541-50-6 Potent cell-permeable anticancer agent whose potential target site may be mitochondrial cytochrome c oxidase. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Daunorubicin hydrochloride impurity 7 Daunorubicin hydrochloride impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125515-17-5. Molecular formula: C21H20O8. Mole weight: 400.38. Catalog: APB125515175. Alfa Chemistry Analytical Products 4
Daunorubicin Hydrochloride (Mixture of Diastereomers) Daunorubicin Hydrochloride (Mixture of Diastereomers). Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride; (8S-cis)-Daunomycin Hydrochloride; Cerubidine; Daunoblastin; Daunomycin Chlorohydrate; ?NDC 0082-4155; Ondena; RP 13057 Hydrochloride; Rubidomycin Hydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
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Daunorubicin impurity 13 Daunorubicin impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 100992-86-7. Molecular formula: C21H20O7. Mole weight: 384.38. Catalog: APB100992867. Alfa Chemistry Analytical Products 4
Daunorubicin Impurity 20 Daunorubicin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,10S)-8-acetyl-10-(((2R,4S,5S,6S)-4-amino-5-(benzyloxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. CAS No. 1010447-40-1. Molecular formula: C34H35NO10. Mole weight: 617.64. Catalog: APB1010447401. Alfa Chemistry Analytical Products 4
Daunorubicinol-13C,d3 (13-(R,S) Dihydrodaunorubicin-13C,d3) Used as an antineoplastic. Complexes with DNA. Inhibits DNA and RNA synthesis. Group: Biochemicals. Alternative Names: 13-(R,S) Dihydrodaunorubicin-13C,d3. Grades: Highly Purified. Pack Sizes: 0.100mg. US Biological Life Sciences. USBiological 1
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Daunorubicinol-D3 BOC Sciences 11
Daunorubicinol hydrochloride Daunorubicinol Hydrochloride is a metabolite of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-, hydrochloride, [8S-[8α,8(R*),10α]]-; 13-Dihydrodaunorubicin Hydrochloride; Duborimycin Hydrochloride; Leukaemomycin D Hydrochloride; L-lyxo-Hexopyranoside, 1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-3-(1-hydroxyethyl)-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-, hydrochloride, (1S,3S)-α-; 13-Dihydrodaunomycin hydrochloride; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-[(1S)-1-hydroxyethyl]-1-methoxy-, hydrochloride (1:1), (8S,10S)-; Antibiotic RP 20798; Antibiotic 20798 RP; Dihydrodaunomycin hydrochloride; NSC 180510. Grades: ≥95%. CAS No. 28008-53-9. Molecular formula: C27H32ClNO10. Mole weight: 566.00. BOC Sciences 9
Daunorubicinone United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alfa Chemistry Analytical Products 4
14-Bromo 4’-epi-Daunorubicin Hydrochloride 14-Bromo 4’-epi-Daunorubicin Hydrochloride is a derivative of Daunorubicin Hydrochloride (D194500), an anthracycline antibiotic related to the rhodomycins. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 99530-17-3. Pack Sizes: 500ug, 5mg. Molecular Formula: C27H28BrNO10 HCl, Molecular Weight: 606.423645999999. US Biological Life Sciences. USBiological 9
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14-Bromo Ketal 4’-epi-Daunorubicin Hydrobromide 14-Bromo Ketal 4’-epi-Daunorubicin Hydrobromide is a derivative of Daunorubicin Hydrochloride (D194500), an anthracycline antibiotic related to the rhodomycins. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C29H34BrNO11 HBr, Molecular Weight: 652.488091. US Biological Life Sciences. USBiological 9
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14-Bromo-N-trifluoroacetamido Daunorubicin Hydrobromide Salt 14-Bromo-N-trifluoroacetamido Daunorubicin Hydrobromide Salt is an intermediate in the synthesis of Doxorubicin Dimer Impurity 1which is an is an impurity of Doxorubicin Hydrochloride (D558000), an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C29H27BrF3NO11. US Biological Life Sciences. USBiological 9
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14-Chloro Daunorubicin Adriamycin analogue; use as anticancer agent. Group: Biochemicals. Alternative Names: 8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-chloroacetyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 14-Chlorodaunomycin; 14-Chlororubomycin. Grades: Highly Purified. CAS No. 121250-06-4. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
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4'-Epi-daunorubicin Cas No. 57918-24-8. BOC Sciences 6
4'-epi-Daunorubicin Hydrochloride 4'-epi-Daunorubicin Hydrochloride is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxynaphthacene-5,12-dione hydrochloride; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride; (8S-cis)-4'-Epidaunorubicin Hydrochloride; 4'-epi-Daunomycin Hydrochloride; NSC 249333; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside hydrochloride (1:1). Grades: 95%. CAS No. 56390-08-0. Molecular formula: C27H29NO10.HCl. Mole weight: 563.99. BOC Sciences 6
4'-Keto-N-(trifluoroacetyl)daunorubicin 4'-Keto-N-(trifluoroacetyl)daunorubicin is an impurity of Epirubicin, which is an anthracycline topoisomerase inhibitor used as an antineoplastic agent. Synonyms: 4'-keto-N-trifluoroacetyl daunorubicin; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-threo-hexopyranos-4-ulos-1-yl]oxy]-5,12-naphthacenedione; (8S-cis)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-threo-hexopyranos-4-ulos-1-yl]oxy]-5,12-naphthacenedione; Epirubicin Impurity 6; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-threo-hexopyranosid-4-ulose. Grades: ≥95%. CAS No. 79441-78-4. Molecular formula: C29H26F3NO11. Mole weight: 621.51. BOC Sciences 12
7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%) (Doxorubicin Impurity) 7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%) (Doxorubicin Impurity). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione, 7,8-Desacetyl-9,10-dehydro Daunorubicinone, Doxorubicin Impurity,6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione. CAS No. 1159977-24-8. IUPAC Name: 1,3,6,11-tetrahydroxy-10-methoxytetracene-5,12-dione. Molecular formula: C19H12O7. Mole weight: 352.29. Catalog: APS1159977248. SMILES: COc1cccc2c(O)c3C(=O)c4cc(O)cc(O)c4C(=O)c3c(O)c12. Format: Neat. Alfa Chemistry Analytical Products 4
7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%)(Doxorubicin Impurity) 7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%)(Doxorubicin Impurity). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1159977-24-8. Pack Sizes: 5MG. IUPAC Name: 1,3,6,11-tetrahydroxy-10-methoxytetracene-5,12-dione. Molecular formula: C19H12O7. Mole weight: 352.29. Catalog: APS1159977248A. SMILES: COc1cccc2c(O)c3C(=O)c4cc(O)cc(O)c4C(=O)c3c(O)c12. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products 4
7,8-Desacetyl-9,10-dehydro Daunorubicinone (Doxorubicin Impurity) Potential degradation product of Doxorubicin. Doxorubicin impurity. Group: Biochemicals. Alternative Names: Doxorubicin Impurity; 6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 1159977-24-8. Pack Sizes: 500ug. Molecular Formula: C??H??O?, Molecular Weight: 352.29. US Biological Life Sciences. USBiological 2
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8-Desacetyl-8-carboxy Daunorubicin Hydrochloride Doxorubicin analog. Antitumor drug. Group: Biochemicals. Alternative Names: (2S-cis)-4-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic Acid; NSC 235816. Grades: Highly Purified. CAS No. 58199-96-5. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
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8-Desacetyl-8-carboxy Daunorubicin Hydrochloride Hydrate 8-Desacetyl-8-carboxy Daunorubicin Hydrochloride Hydrate is an analog of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic acid hydrochloride hydrate; NSC 235816 Hydrate; 2-Naphthacenecarboxylic acid, 3,6-trideoxy-α-L-Lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-, (2S-cis)-, hydrochloride, Hydrate (1:1:x). Grades: ≥95%. Molecular formula: C26H27NO11.HCl.xH2O. Mole weight: 565.96 (anhydrous). BOC Sciences 8
9,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin Hydrochloride 9,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00614. Format: Neat. Alfa Chemistry Analytical Products 4
Ala-leu-ala-leu daunorubicin hydrochloride Ala-leu-ala-leu daunorubicin hydrochloride. Group: Biochemicals. Alternative Names: (8S-cis)-8-Acetyl-10-[[3-[[N-[N-(N-L-alanyl-L-leucyl)-L-alanyl]-L-leucyl]amino]-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione monohydrochloride; Ala-leu-ala-leu-DNR. Grades: Highly Purified. CAS No. 76582-70-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C45H62ClN5O14. US Biological Life Sciences. USBiological 6
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Hydrochloric Daunorubicin Liposome Hydrochloric daunorubicin is a broad-spectrum anthracycline antitumor drug. This product is a PEGylated pre-formulated liposome with hydrochloric daunorubicin. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. Creative Biolabs
N-Trifluoroacetamido-4'-p-nitrobenzoyl daunorubicin N-Trifluoroacetamido-4'-p-nitrobenzoyl daunorubicin. Group: Biochemicals. Alternative Names: (8S-cis) -8-Acetyl-7, 8, 9, 10-tetrahydro-6, 8, 11-trihydroxy-1-methoxy-10-[[2, 3, 6-trideoxy-4-O- (4-nitrobenzoyl) -3-[ (trifluoroacetyl) amino]-a-L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione. Grades: Highly Purified. CAS No. 52583-24-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C36H31F3N2O14. US Biological Life Sciences. USBiological 5
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N-Trifluoroacetamido-4’-p-nitrobenzoyl Daunorubicin-13CD3 Intermediate in the production of labeled Daunorubicin. Group: Biochemicals. Alternative Names: (8S-cis) -8-Acetyl-7, 8, 9, 10-tetrahydro-6, 8, 11-trihydroxy-1-methoxy-10-[[2, 3, 6-trideoxy-4-O- (4-nitrobenzoyl) -3-[ (trifluoroacetyl) amino]-α -L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione-13CD3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
N-(Trifluoroacetyl)-1-desmethyl daunorubicin N-(Trifluoroacetyl)-1-desmethyl Daunorubicin is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (8S-cis)-8-Acetyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione; (8S,10S)-8-acetyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione; (1S,3S)-3-Acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranoside. Grades: ≥95%. CAS No. 68594-06-9. Molecular formula: C28H26F3NO11. Mole weight: 609.50. BOC Sciences 11
N-(Trifluoroacetyl)-1-desmethyl Daunorubicin Daunorubicinc derivative. Group: Biochemicals. Alternative Names: (8S-cis) -8-Acetyl-7, 8, 9, 10-tetrahydro-1, 6, 8, 11-tetrahydroxy-10-[[2, 3, 6-trideoxy-3-[ (trifluoroacetyl) amino]-α -L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione; (8S, 10S) -8-acetyl-7, 8, 9, 10-tetrahydro-1, 6, 8, 11-tetrahydroxy-10-[[2, 3, 6-trideoxy-3-[ (trifluoroacetyl) amino]-α -L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione. Grades: Highly Purified. CAS No. 68594-06-9. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 3
Worldwide
N- (Trifluoroacetyl) daunorubicin Protected Daunorubicin. Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 26388-52-3. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 3
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N- (Trifluoroacetyl) daunorubicin-13CD3 Protected Daunorubicin. Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione-13CD3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 3
Worldwide
1,4-Di-O-butanoyl-2,3:5,6-di-O-isopropylidene-D-myo-inositol 1,4-Di-O-butanoyl-2,3:5,6-di-O-isopropylidene-D-myo-inositol is a complex chemical compound widely employed in the pharmaceutical industry. It is an essential building block for a multitude of drugs with diverse antitumor activities, including the potent 4-epi-doxorubicin and daunorubicinone. Impressively, this versatile compound can also facilitate the synthesis of potent antiviral and antibacterial agents, thus making it a vital component for modern-day pharmaceutical research and development. Synonyms: (3AR,4S,4aS,7aS,8S,8aS)-2,2,6,6-tetramethylhexahydrobenzo[1,2-d:4,5-d']bis([1,3]dioxole)-4,8-diyl dibutyrate; [(1S,3R,7S,9S)-8-butanoyloxy-5,5,11,11-tetramethyl-4,6,10,12-tetraoxatricyclo[7.3.0.03,7]dodecan-2-yl] butanoate. CAS No. 1620222-02-7. Molecular formula: C20H32O8. Mole weight: 400.46. BOC Sciences 11
14-O-Acetyldaunomycinone Protected Daunomycinone, the main metabolite of Daunorubicin (DNR). Group: Biochemicals. Alternative Names: 14-O-Acetyladriamycinone; (8S,10S)-8-[2-(Acetyloxy)acetyl]-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; (8S,cis)-8-[2-(Acetyloxy)acetyl]-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 29984-41-6. Pack Sizes: 500ug. US Biological Life Sciences. USBiological 1
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4-Demethyl Daunomycinone A metabolite Daunorubicin. Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-1,6,8,10,11-pentahydroxy-5,12-naphthacenedione; (+)-Carminomycinone; 4-Demethoxy-4-hydroxydaunomycinone; 4-O-Demethyldaunomycinone; Carminomycinone. Grades: Highly Purified. CAS No. 52744-22-6. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
4-Epi-daunosamine 4-Epi-daunosamine is an essential compound widely utilized in the biomedical field, holding immense significance in research of a plethora of diseases, particularly cancer. In the realm of chemotherapy, it serves as an indispensable precursor, facilitating the research and development of influential antibiotics, namely daunorubicin and doxorubicin. Synonyms: L-arabino-Hexose, 3-amino-2,3,6-trideoxy- Acosamine. CAS No. 41094-24-0. Molecular formula: C6H11NO3. Mole weight: 145.16. BOC Sciences 11
6,9,11-Trihydroxy-9-(1-hydroxyethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 6,9,11-Trihydroxy-9-(1-hydroxyethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Deoxydaunorubicinol aglycone, 7-Deoxy-13-dihydrodaunorubicinone, CID99903, NSC258819, NSC283832, NSC 258819, DAUNORUBICINOL, 7-DEOXY- AGLYCONE, 35994-55-9, 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-. Product Category: Heterocyclic Organic Compound. CAS No. 35994-55-9. Molecular formula: C21H20O7. Mole weight: 384.379 g/mol. Purity: 0.96. IUPACName: 6,9,11-trihydroxy-9-(1-hydroxyethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione. Canonical SMILES: CC(C1(CCC2=C(C3=C(C(=C2C1)O)C(=O)C4=C(C3=O)C(=CC=C4)OC)O)O)O. Density: 1.505g/cm³. Product ID: ACM35994559. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
(8S, 10S) -10- ( (tert-Butyldimethylsilyl) oxy) -6, 8, 11-trihydroxy-8- (1-hydroxyethyl) -1-methoxy-7, 8, 9, 10-tetrahydrotetracene-5, 12-dione (8S, 10S) -10- ( (tert-Butyldimethylsilyl) oxy) -6, 8, 11-trihydroxy-8- (1-hydroxyethyl) -1-methoxy-7, 8, 9, 10-tetrahydrotetracene-5, 12-dione is a protected derivative of Dihydrodaunomycinone (D448555), an impurity of Daunorubicin (D194500), a anthracycline antibiotic related to the rhodomycins. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. USBiological 3
Worldwide
(8S,10S)-8-Acetyl-6,8,11-trihydroxy-1-methoxy-10-((tetrahydro-2H-pyran-2-yl)oxy)-7,8,9,10-tetrahydrotetracene-5,12-dione (8S,10S)-8-Acetyl-6,8,11-trihydroxy-1-methoxy-10-((tetrahydro-2H-pyran-2-yl)oxy)-7,8,9,10-tetrahydrotetracene-5,12-dione is an impurity of Daunorubicin (D194500), a anthracycline antibiotic related to the rhodomycins and is known to exhibit antineoplastic properties. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
Aclarubicin hydrochloride Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Synonyms: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grades: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33. BOC Sciences
aklanonic acid methyl ester cyclase The enzyme is involved in the biosynthesis of aklaviketone, an intermediate in the biosynthetic pathways leading to formation of several anthracycline antibiotics, including aclacinomycin, daunorubicin and doxorubicin. Group: Enzymes. Synonyms: dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5624; aklanonic acid methyl ester cyclase; EC 5.5.1.23; dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Cat No: EXWM-5624. Creative Enzymes
aklanonic acid methyltransferase The enzyme from the Gram-positive bacterium Streptomyces sp. C5 is involved in the biosynthesis of the anthracycline daunorubicin. Group: Enzymes. Synonyms: DauC; AAMT. Enzyme Commission Number: EC 2.1.1.288. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1895; aklanonic acid methyltransferase; EC 2.1.1.288; DauC; AAMT. Cat No: EXWM-1895. Creative Enzymes
aklaviketone reductase The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin. Group: Enzymes. Synonyms: dauE (gene name); aknU (gene name). Enzyme Commission Number: EC 1.1.1.362. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0279; aklaviketone reductase; EC 1.1.1.362; dauE (gene name); aknU (gene name). Cat No: EXWM-0279. Creative Enzymes
aklavinone 12-hydroxylase The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase. Group: Enzymes. Synonyms: DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Enzyme Commission Number: EC 1.14.13.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0779; aklavinone 12-hydroxylase; EC 1.14.13.180; DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Cat No: EXWM-0779. Creative Enzymes
Baumycin C1 Baumycin C1, an impurity of Daunorubicin and Doxorubicin, is an anthracycline antibiotic isolated from Streptomyces coeruleorubidus. Baumycin C1 shows antitumor activity. Synonyms: N-((2S,3S,4S,6R)-6-(((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)formamide; N-Formyldaunorubicin; NSC 227012; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-((2,3,6-trideoxy-3-(formylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (8S-cis)-; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[(3-(formylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-5,12-naphthacenedione. Grades: ≥95%. CAS No. 63084-42-4. Molecular formula: C28H29NO11. Mole weight: 555.53. BOC Sciences 5
Berubicin Berubicin has potential antineoplastic activity. Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, and RNA and protein synthesis. Synonyms: Daunorubicin Impurity 9; RTA 744; RTA-744; RTA744; WP 769; WP769; WP-769; 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(phenylmethyl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-. Grades: ≥95% by HPLC. CAS No. 677017-23-1. Molecular formula: C34H35NO11. Mole weight: 633.65. BOC Sciences 5
Berubicin Hydrochloride Berubicin hydrochloride is the hydrochloride of berubicin, which is an anthracycline derivative used as a topoisomerase II inhibitor with activity in ependymoma. Berubicin hydrochloride has potential antineoplastic activity. Uses: A topoisomerase ii inhibitor with activity in ependymoma. Synonyms: Daunorubicin Impurity 9 hydrochloride; RTA 744 hydrochloride; WP 769 hydrochloride; 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(phenylmethyl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-, hydrochloride (1:1). Grades: ≥95%. CAS No. 293736-67-1. Molecular formula: C34H35NO11.HCl. Mole weight: 670.10. BOC Sciences 6
carbonyl reductase (NADPH) Acts on a wide range of carbonyl compounds, including quinones, aromatic aldehydes, ketoaldehydes, daunorubicin and prostaglandins E and F, reducing them to the corresponding alcohol. Si-specific with respect to NADPH [cf. EC 1.1.1.2 alcohol dehydrogenase (NADP+)]. Group: Enzymes. Synonyms: aldehyde reductase 1; prostaglandin 9-ketoreductase; xenobiotic ketone reductase; NADPH-dependent carbonyl reductase; ALR3; carbonyl reductase; nonspecific NADPH-dependent carbonyl reductase; carbonyl reductase (NADPH2). Enzyme Commission Number: EC 1.1.1.184. CAS No. 89700-36-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0086; carbonyl reductase (NADPH); EC 1.1.1.184; 89700-36-7; aldehyde reductase 1; prostaglandin 9-ketoreductase; xenobiotic ketone reductase; NADPH-dependent carbonyl reductase; ALR3; carbonyl reductase; nonspecific NADPH-dependent carbonyl reductase; carbonyl reductase (NADPH2). Cat No: EXWM-0086. Creative Enzymes
carminomycin 4-O-methyltransferase The enzymes from the Gram-positive bacteria Streptomyces sp. C5 and Streptomyces peucetius are involved in the biosynthesis of the anthracycline daunorubicin. In vitro the enzyme from Streptomyces sp. C5 also catalyses the 4-O-methylation of 13-dihydrocarminomycin, rhodomycin D and 10-carboxy-13-deoxycarminomycin. Group: Enzymes. Synonyms: DnrK; DauK. Enzyme Commission Number: EC 2.1.1.292. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1899; carminomycin 4-O-methyltransferase; EC 2.1.1.292; DnrK; DauK. Cat No: EXWM-1899. Creative Enzymes
Daunomycin Daunomycin is an intermediate of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 8-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 8-Acetyl-6,10,11-trihydroxy-1-methoxytetracene-5,12-dione; 8-Acetyl-5,12-dihydro-6,10,11-trihydroxy-1-methoxynaphthacene-5,12-dione; 5,12-Naphthacenedione, 8-acetyl-6,10,11-trihydroxy-1-methoxy-; Daunorubicin Impurity 5. Grades: ≥95%. CAS No. 20982-41-6. Molecular formula: C21H14O7. Mole weight: 378.33. BOC Sciences 11
Daunomycinone Daunomycinone. Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy- -5,12-naphthacenedione; (+)-Daunomycinone; Daunomycin aglicone; Daunorubicinone. Grades: Highly Purified. CAS No. 21794-55-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C21H18O8. US Biological Life Sciences. USBiological 7
Worldwide
Daunomycinone-d3 The main metabolite of labeled Daunorubicin (DNR). Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy- -5,12-naphthacenedione-d3; (+)-Daunomycinone-d3; Daunomycin Aglicone-d3; Daunomycinon-d3; Daunorubicin Aglycone-d3; Daunorubicinone-d3; Leukaemomycinone C-d3; NSC 109351-d3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. USBiological 2
Worldwide
Detorubicin Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin. Check for active clinical trials or closed clinical trials using this agent. Synonyms: MCMC 4777; MCMC4777; MCMC-4777; NSC 292652; NSC-292652; NSC292652; (1S,3S)-3-(Diethoxyacetoxyacetyl)-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl-3-amino-2,36-tridesoxy-alpha-L-lyxo-hexopyranosid. CAS No. 66211-92-5. Molecular formula: C33H39NO14. Mole weight: 673.67. BOC Sciences 11
Doxorubicin, Hydrochloride (Adriacin, Adriblastina, Adriamycin, Caelyx) The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. Group: Biochemicals. Alternative Names: Adriacin, Adriblastina, Adriamycin, Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. USBiological 1
Worldwide
Doxorubicin Impurity 1 Doxorubicin Impurity 1 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity; 6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione; 7,8-Desacetyl-9,10-dehydro Daunorubicinone; 5,12-Naphthacenedione, 6,8,10,11-tetrahydroxy-1-methoxy-; Xanthone Impurity 13. Grades: > 95%. CAS No. 1159977-24-8. Molecular formula: C19H12O7. Mole weight: 352.29. BOC Sciences 8
Doxorubicin Impurity 6 Doxorubicin Impurity 6 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 9-Carboxy Doxorubicin Impurity; (2S,4S)-4-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-2-carboxylic acid; (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic Acid; 2-Naphthacenecarboxylic acid, 4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-, (2S-cis)-; 8-Desacetyl-8-carboxy Daunorubicin. Grades: > 95%. CAS No. 69429-21-6. Molecular formula: C26H27NO11. Mole weight: 529.49. BOC Sciences 8

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