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Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cholanoic Acid; Desoxycholic acid. CAS No. 83-44-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0593.
Deoxycholic acid
Deoxycholic acid is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Deoxycholic acid is specifically responsible for activating the G-protein-coupled bile acid receptor TGR5, stimulating the thermogenic activity of brown adipose tissue (BAT). Uses: Hypotensive. Synonyms: Cholanoic Acid; Desoxycholic acid; 3α,12α-dihydroxy-5β-cholanate; Deoxycholate; Cholerebic; Degalol; Droxolan; Pyrochol; 5β-cholanic acid-3α,12α-diol; 7-Deoxycholic acid; 5β-Deoxycholic Acid; NSC 8797; Septocholl; Ursodeoxycholic Acid EP Impurity E. Grade: 98%. CAS No. 83-44-3. Molecular formula: C24H40O4. Mole weight: 392.58.
Deoxycholic Acid
Deoxycholic acid (DCA) is a bile acid that plays an important role in the digestion and absorption of dietary fats and fat-soluble vitamins. Uses: It is a natural component of the human body and is produced in the liver from cholesterol. it is also used in laboratory experiments to study the effects of bile acids on cell physiology, metabolism, and gene expression. Additional or Alternative Names: Choleic acid. Product Category: Heterocyclic Organic Compound. Appearance: White to off-white solid. CAS No. 83-44-3. Molecular formula: C24H40O4. Mole weight: 392.58. Purity: 0.98. IUPACName: (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Canonical SMILES: CC(CCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C. Density: 1.1±0.1 g/mL. ECNumber: 201-478-5. Product ID: ACM83443-1. Alfa Chemistry ISO 9001:2015 Certified.
Deoxycholic Acid-2,2,3,4,4-d5 3-O- β-D-Glucuronide Disodium Salt
Deoxycholic Acid-2,2,3,4,4-d5 3-O- β-D-Glucuronide Disodium Salt is a labelled analogue of Deoxycholic Acid 3-O- β-D-Glucuronide Disodium Salt (D232720), an impurity of Cholic Acid (C432600), which is a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2mg. Molecular Formula: C30H41D5Na2O10, Molecular Weight: 617.69. US Biological Life Sciences.
Worldwide
Deoxycholic acid-[2,2,4,4-d4]
Deoxycholic acid-2,2,4,4-d4 is a deuterated compound and a deoxycholic acid. Synonyms: 7-Deoxycholic acid,-2,2,4,4-d4; 3a,12a-Dihydroxy-5β-cholanic acid-2,2,4,4-d4; Desoxycholic acid-2,2,4,4-d4. Grade: 98% by CP; 98% atom D. CAS No. 112076-61-6. Molecular formula: C24H36D4O4. Mole weight: 396.60.
Deoxycholic acid-[24-13C]
Labelled Deoxycholic acid. Deoxycholic acid, also known as deoxycholate, cholanoic acid, and 3α,12α-dihydroxy-5β-cholanate, is a bile acid. Deoxycholic acid is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Deoxycholic acid is soluble in alcohol and acetic acid. When pure, it comes in a white to off-white crystalline powder form. Synonyms: 3a,12a-Dihydroxy-5β-cholanic acid-24-13C; 7-Deoxycholic acid-24-13C. Grade: 99% atom 13C. CAS No. 52886-37-0. Molecular formula: C23[13C]H40O4. Mole weight: 393.56.
Deoxycholic Acid 3-O-β-D-Glucuronide-2,2,3,4,4-[d5] Disodium Salt
Deoxycholic Acid 3-O-β-D-Glucuronide-2,2,3,4,4-[d5] Disodium Salt is the labelled salt of Deoxycholic Acid 3-O-β-D-Glucuronide, which is an impurity of Cholic Acid. Synonyms: Deoxycholic Acid-2,2,3,4,4-d5 3-O-β-D-Glucuronide Disodium Salt; (3α,5β,12α)-23-Carboxy-12-hydroxy-24-norcholan-3-yl-β-D-glucopyranosiduronic Acid-d5 Disodium Salt. Grade: >98%. Molecular formula: C30H41D5Na2O10. Mole weight: 617.69.
Deoxycholic Acid 3-O- β-D-Glucuronide Disodium Salt
Deoxycholic Acid 3-O- β-D-Glucuronide Disodium Salt is an impurity of Cholic Acid (C432600), a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 59274-67-8. Pack Sizes: 1mg, 2mg. Molecular Formula: C30H46Na2O10, Molecular Weight: 612.66. US Biological Life Sciences.
Worldwide
Deoxycholic Acid 3-O-β-D-Glucuronide Disodium Salt
Deoxycholic Acid 3-O-β-D-Glucuronide Disodium Salt is an impurity of Cholic Acid, a choleretic produced by and isolated from liver cells. Synonyms: (3α,5β,12α)-23-Carboxy-12-hydroxy-24-norcholan-3-yl-β-D-glucopyranosiduronic acid disodium salt; (2S,3S,4S,5R,6R)-6-(((3R,5R,8R,9S,10S,12S,13R,14S,17R)-17-((R)-4-carboxylatobutan-2-yl)-12-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate disodium salt. Grade: 98%. CAS No. 59274-67-8. Molecular formula: C30H46Na2O10. Mole weight: 612.66.
Deoxycholic acid-D4
100 ?g/mL in methanol, certified reference material. Group: Bile acid standards.
Deoxycholic Acid-[d5]
Deoxycholic Acid-[d5] is the labelled analogue of Deoxycholic Acid, which is a cholic acid derivative used as a component in cell lysis buffers. Synonyms: Deoxycholic Acid D5; 3α,12α-Dihydroxy-5β-cholanoic Acid-d5; 3α,12α-Dihydroxycholanic Acid-d5; 5β-Cholanic Acid-3α,12α-diol-d5; 5β-Deoxycholic Acid-d5; 7-Deoxycholic Acid-d5; Cholerebic-d5; Cholorebic-d5; Degalol-d5; Deoxycholatic Acid-d5; Desoxycholic Acid-d5; Droxolan-d5; NSC 8797-d5; Pyrochol-d5; Septochol-d5. Grade: 97%; ≥97% atom D. CAS No. 52840-14-9. Molecular formula: C24H35D5O4. Mole weight: 397.60.
Deoxycholic Acid-d5 3-O-Sulfate Disodium Salt
Deoxycholic Acid-d5 3-O-Sulfate Disodium Salt is a labelled impurity of Cholic Acid (C432600), it is produced and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C24H33D5Na2O7S, Molecular Weight: 521.63. US Biological Life Sciences.
Worldwide
Deoxycholic acid sodium salt
100g Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C24H39NaO4. CAS No. 302-95-4. Prepack ID 13082357-100g. Molecular Weight 414.55. See USA prepack pricing.
Deoxycholic acid sodium salt
Deoxycholic acid sodium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
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Deoxycholic acid sodium salt
Deoxycholic acid sodium salt (sodium deoxycholate), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium deoxycholate. CAS No. 302-95-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0593A.
12α-Deoxycholic Acid Methyl Ester 3α-Benzoate
12α-Deoxycholic Acid Methyl Ester 3α-Benzoate is an intermediate in the synthesis of 3α,12α-Dihydroxy-5 β-chol-9(11)-enic Acid which is used in the analysis and in the structure determination of unsaturated 5 β-cholanoic acids. Group: Biochemicals. Grades: Highly Purified. CAS No. 5969-28-8. Pack Sizes: 50mg, 100mg. Molecular Formula: C32H46O5. US Biological Life Sciences.
Worldwide
12 β-Deoxycholic Acid Methyl Ester 3α-Benzoate
12 β-Deoxycholic Acid Methyl Ester 3α-Benzoate is an intermediate in the synthesis of 3α,12 β-Dihydroxycholanoic Acid is a bile acid that may decrease of the toxic effects of deoxycholic acid on lipid peroxidn. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C32H46O5. US Biological Life Sciences.
Worldwide
1β-Hydroxydeoxycholic acid
1β-Hydroxydeoxycholic acid is a secondary bile acid that serves as a biomarker for CYP3A, a group of enzymes involved in drug metabolism. It is formed from deoxycholic acid (DCA) through the specific metabolism by CYP3A4 and CYP3A7 enzymes. This compound is used in research to assess the potential for drug-drug interactions (DDI) involving CYP3A, as it can indicate the activity of these enzymes in the liver and intestines. Synonyms: Cholan-24-oic acid, 1,3,12-trihydroxy-, (1β,3α,5β,12α)-; (1β,3α,5β,12α)-1,3,12-Trihydroxycholan-24-oic acid; 1β,3α,12α-Trihydroxy-5β-cholan-24-oic acid; 1β,3α,12α-Trihydroxy-5β-cholanoic acid; 1Beta-Hydroxydeoxycholic acid; Deoxycholic Acid (1R)-Hydroxy Impurity; Ursodeoxycholic Acid Impurity 31; Chenodeoxycholic Acid Impurity 13; 1β-OH-DCA. Grade: ≥95%. CAS No. 80434-32-8. Molecular formula: C24H40O5. Mole weight: 408.57.
1 β-Hydroxydeoxycholic Acid-d5
1 β-Hydroxydeoxycholic Acid-d5 is the isotope labelled analog of 1 β-Hydroxydeoxycholic Acid (H934880); a metabolite of Taurodeoxycholic Acid (T009000) which is a steroidal amphipathic hepatic bile salt formed in the liver through the conjugation of Deoxycholate (S624090) with Taurine (T007850). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H35D5O5, Molecular Weight: 413.6. US Biological Life Sciences.
Worldwide
1β-Hydroxytaurodeoxycholic Acid
1β-Hydroxytaurodeoxycholic Acid is a metabolite of Deoxycholic Acid. Synonyms: Ethanesulfonic acid, 2-[[(1β,3α,5β,12α)-1,3,12-trihydroxy-24-oxocholan-24-yl]amino]-. CAS No. 111945-04-1. Molecular formula: C26H45NO7S. Mole weight: 515.71.
3β-Deoxycholic acid
3β-Deoxycholic acid is a bile acid derivative that is not commonly found in natural bile but can be synthesized or studied in a laboratory setting. Bile acids, including deoxycholic acid, are important for the digestion and absorption of fats in the intestine. They act as natural detergents to emulsify fat globules, aiding in the digestion of lipids. While 3β-deoxycholic acid is not a major component of bile, it may be of interest in research for understanding bile acid metabolism and its role in lipid digestion. Synonyms: Cholan-24-oic acid, 3,12-dihydroxy-, (3β,5β,12α)-; (3β,5β,12α)-3,12-Dihydroxycholan-24-oic acid; 3-Epideoxycholic acid; 3β,12α-Dihydroxy-5β-cholan-24-oic acid; 3β,12α-Dihydroxy-5β-cholanic acid; 3β,12α-Dihydroxy-5β-cholanoic acid; 3β,12α-Dihydroxycholanoic acid; 3Beta-Deoxycholic Acid; 5β-Cholanic acid-3β,12α-diol; 7-Deoxycholic acid; Isodeoxycholic acid; 3β-DCA; EDCA. Grade: ≥95%. CAS No. 570-63-8. Molecular formula: C24H40O4. Mole weight: 392.57.
3-Epideoxycholic acid
3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR of dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exhibits anti-inflammatory activity. 3-Epideoxycholic acid promotes the growth of bacteria Bacteroides [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 570-63-8. Pack Sizes: 5 mg. Product ID: HY-48814.
3-Oxo deoxycholic acid
3-oxo Deoxycholic acid is a secondary bile acid and a metabolite of Deoxycholic acid (HY-N0593) in C. perfringens [1]. Uses: Scientific research. Group: Natural products. CAS No. 4185-1-7. Pack Sizes: 5 mg. Product ID: HY-W391635.
7-keto-Deoxycholic acid
7-keto-Deoxycholic acid is a metabolite of bile acids in Clostridium absonum. 7-keto-Deoxycholic acid is also converted from Lactobacillus and Bifidobacterium with specific condition [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 911-40-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-41324.
Deoxycholic-2,2,4,4,11,11-d6 acid
?98 atom % D, ?98% (CP). Group: Fluorescence/luminescence spectroscopy.
Deoxycholic-2,2,4,4-d4 acid 3-sulfate disodium salt
?98 atom % D, ?98% (CP). Group: Fluorescence/luminescence spectroscopy.
Glycodeoxycholic acid-[2,2,4,4-d4]
Glycodeoxycholic acid-2,2,4,4-[d4] is the labelled analogue of Glycodeoxycholic acid. Glycodeoxycholic acid is a bile acid formed in the liver by the conjugation of deoxycholate with glycine. Glycodeoxycholic acid can be used as a cholagogue and choleretic. Synonyms: Glycodeoxycholic-2,2,4,4-d4 acid; N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine-d4; 3α,12α-Dihydroxy-5β-cholanoic Acid N-(Carboxymethyl)amide-d4; N-[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]glycine; Glycodeoxycholic Acid-d4; N-[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]-glycine. Grade: ≥ 98% (CP); 98% atom D. CAS No. 1069132-37-1. Molecular formula: C26H39D4NO5. Mole weight: 453.65.
A derivative of Deoxycholic acid (DC); the bile acid nor-DC showed considerable and continuing efflux into the perfusate; this involved mostly the unchanged acid. Nor-DC was not amidated but was metabolized to mostly ester glucuronides and hydroxylated derivatives. Group: Biochemicals. Alternative Names: (3α,5 β,12α)-3,12-Dihydroxy-24-norcholan-23-oic Acid; 23-Nordeoxycholic Acid; 24-Nordeoxycholic Acid; 3α,12α-Dihydroxy-24-nor-5 β-cholan-23-oic Αcid; Nordeoxycholic Acid. Grades: Highly Purified. CAS No. 53608-86-9. Pack Sizes: 100mg, 250mg. US Biological Life Sciences.
Worldwide
Taurochenodeoxycholic acid
Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 12-Deoxycholyltaurine. CAS No. 516-35-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N2027.
Taurochenodeoxycholic acid sodium
Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 12-Deoxycholyltaurine sodium. CAS No. 6009-98-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1429.
Taurochenodeoxycholic acid (sodium) (Standard)
Taurochenodeoxycholic acid (sodium) (Standard) is the analytical standard of Taurochenodeoxycholic acid (sodium). This product is intended for research and analytical applications. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6009-98-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1429R.
Taurodeoxycholic acid
Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholic acid is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholic acid is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholic acid (TDCA) exhibits anti-inflammatory and neuroprotective effects [1] [2] [3] [9] [10]. Uses: Scientific research. Group: Natural products. CAS No. 516-50-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1899.
Ursodeoxycholic acid
Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate; Ursodiol; UDCA. CAS No. 128-13-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-13771.
Ursodeoxycholic acid-2,2,4,4-d4
Ursodeoxycholic acid-2,2,4,4-d 4 is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection[1][2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 347841-46-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-113478S.
Ursodeoxycholic acid sodium
Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid sodium can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium. CAS No. 2898-95-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-13771A.
(3α,5 β)-3-(Benzoyloxy)-12-oxo-cholan-24-oic Acid Methyl Esteris an intermediate in the synthesis of 3α,12 β-Dihydroxycholanoic Acid is a bile acid that may decrease of the toxic effects of deoxycholic acid on lipid peroxidn. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C32H44O5. US Biological Life Sciences.
Worldwide
5β-Cholanic acid-3,12-dione
5β-Cholanic acid-3,12-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,12-Dioxo-5beta-cholanoic acid; 3,12-dioxo-7-deoxycholic acid; EINECS 220-982-6; Cholic acid,dehydrodeoxy; Dehydrodeoxycholic acid; 3,12-dioxo-cholanic acid; 3,12-dioxocholanoic acid; 3,12-Diketo-5beta-cholanic acid. Product Category: Steroidal Compounds. CAS No. 2958-5-6. Molecular formula: C24H36O4. Mole weight: 388.54. Purity: 0.95. IUPACName: (4R)-4-[(5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,12-dioxo-2,4,5,6,7,8,9,11,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoicacid. Canonical SMILES: CC(CCC(=O)O)C1CCC2C1(C(=O)CC3C2CCC4C3(CCC(=O)C4)C)C. Density: 1.12g/cm³. ECNumber: 220-982-6. Product ID: ACM2958056. Alfa Chemistry ISO 9001:2015 Certified.
5β-Cholanic acid-3α,12α-diol methyl ester
5β-Cholanic acid-3α,12α-diol methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: METHYL DESOXYCHOLATE;METHYL DEOXYCHOLATE;DEOXYCHOLIC ACID METHYL ESTER;5-BETA-CHOLAN-24-OIC ACID-3-ALPHA,12-ALPHA-DIOL METHYL ESTER;5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL METHYL ESTER;3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID METHYL ESTER;de. Product Category: Steroidal Compounds. Appearance: White Crystalline Solid. CAS No. 3245-38-3. Molecular formula: C25H42O4. Mole weight: 406.6. Purity: 0.95. IUPACName: Methyl Desoxycholate. Density: 1.089 g/cm³. Product ID: ACM3245383. Alfa Chemistry ISO 9001:2015 Certified.
5β-Cholanic acid-7α,12α-diol
5β-Cholanic acid-7α,12α-diol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Isodesoxycholsaeure; ISODEOXYCHOLIC ACID; 3-deoxycholic acid; 7ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLANIC ACID; PHOENO-DEOXYCHOLIC ACID. Product Category: Steroidal Compounds. CAS No. 566-17-6. Molecular formula: C24H40O4. Mole weight: 392.57. Purity: 0.95. IUPACName: 5-β-CHOLANIC ACID-7-α, 12-α-DIOL. Density: 1.128 g/cm³. Product ID: ACM566176. Alfa Chemistry ISO 9001:2015 Certified.
Cholic acid
Cholic acid. Synonyms: Cholalic Acid. CAS No. 81-25-4. Product ID: PE-0435. Molecular formula: C24H40O5. Mole weight: 408.32. Category: Dispersants. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Cholic acid; Dispersion Excipients; Dispersants; C24H40O5; 81-25-4; 81-25-4. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Keep sealed and away from light in a cool and dry place. Source and Preparation: All kinds of cholic acids can be combined with glycine or taurine with peptide bonds to form various bile acids. The bile of pig, cow and sheep was hydrolyzed with cholecylanin and alkali, and the pH was adjusted to 3.0 with hydrochloric acid. The precipitates were extracted and washed to neutral, refined with ethanol and activated carbon, washed with glacial acetic acid, and recrystallized. There are several kinds of cholic acids due to the different number and location of hydroxyl groups. The main ones are 3, 7, 12-trihydroxycholic acid and deoxycholic acid (i.e. 3, 12-dihydroxycholic acid). Safety: This product is non-toxic, ADI 0-1.25MG/kg.
Cholic acid
Cholic acid. Synonyms: Cholalic Acid. CAS No. 81-25-4. Product ID: PE-0570. Molecular formula: C24H40O5. Mole weight: 408.32. Category: Polymer Solid Dispersant; Emulsifier. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0570; Cholic acid; Polymer Solid Dispersant; Emulsifier; C24H40O5; 81-25-4. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Keep sealed and away from light in a cool and dry place. Source and Preparation: All kinds of cholic acids can be combined with glycine or taurine with peptide bonds to form various bile acids. The bile of pig, cow and sheep was hydrolyzed with cholecylanin and alkali, and the pH was adjusted to 3.0 with hydrochloric acid. The precipitates were extracted and washed to neutral, refined with ethanol and activated carbon, washed with glacial acetic acid, and recrystallized. There are several kinds of cholic acids due to the different number and location of hydroxyl groups. The main ones are 3, 7, 12-trihydroxycholic acid and deoxycholic acid (i.e. 3, 12-dihydroxycholic acid). Safety: This product is non-toxic, ADI 0~1.25MG/kg.
Ethyl Deoxycholate
Ethyl Deoxycholate is the ethyl ester of the common bile salt Deoxycholic Acid (D232645), a Cholic Acid (C432600) derivative used as a component in cell lysis buffers. Group: Biochemicals. Grades: Highly Purified. CAS No. 69519-35-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C26H44O4, Molecular Weight: 420.63. US Biological Life Sciences.
Worldwide
Nor-Desoxycholic Acid
Nor-Desoxycholic Acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,12-DIHYDROXY-NOR-CHOLANIC ACID;23-NOR-5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL;23-NORDEOXYCHOLIC ACID;3-ALPHA,12-ALPHA-DIHYDROXYNORCHOLANATE;5BETA-CHOLANIC ACID-23-NOR-3ALPHA,12ALPHA-DIOL;NOR-DEOXYCHOLIC ACID;NOR-DESOXYCHOLIC ACID;3,12-Dihydroxy-nor. Product Category: Steroidal Compounds. Appearance: White Crystalline Solid. CAS No. 53608-86-9. Molecular formula: C23H38O4. Mole weight: 378.55. Purity: 0.95. IUPACName: (3R)-3-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butanoic acid. Canonical SMILES: C[C@H](CC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@H]4(C)[C@H]3C[C@H](O)[C@. Density: 1.142g/cm³. Product ID: ACM53608869. Alfa Chemistry ISO 9001:2015 Certified.
Ox bile extract powder
Bile Extract Powder (Ox Bile Desiccated), dried or desiccated which contains ox bile acids. This powder is specifically been developed for Pharmaceutical Industry, which is prepared by a low temperature dehydration process which ensures a uniform product. Bile Extract Powder, dried is a mixture of conjugated bile acids (Cholic Acid, Deoxycholic Acid, Taurocholic and Glycocholic Acids). It is a straight forward drying of Ox Bile liquid, which contains all of the constituents characteristics, found in Ox Bile. None of the bile salts, bile pigments cholesterol, mucin, etc. has been removed. Applications: Bile extract powder is used to emulsify lipids in food passing through the intestine to enable fat digestion and absorption through the intestinal wall. bile salts aid in the breakdown of saturated fats that the digestive system has not been able to convert into unsaturated fats. the body uses these unsaturated fats to manufacture essential vitamins and hormones. many individuals without proper gallbladder function find it helpful to supplement with the best bile salts. Group: Others. Synonyms: Ox bile extract; Ox bile; BILE SALT; Ox . Ox bile extract powder. Activity: Cholic acid 40%-55%. Appearance: Greenish to yellowish colour free flowing powder. Source: Ox bile. Ox bile extract powder; Ox bile extract; Ox bile; BILE SALT; Ox bile powder. Cat No: OBE-001.
Sodium Taurocholate
Sodium taurocholate is a detergent useful for the solubilization of lipids and membrane-bound proteins. Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid. These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid. Group: Biochemicals. Alternative Names: Monosodium Taurocholate; Sodium Taurocholate; Taurocholate Sodium; Taurocholic Acid Monosodium Salt; Taurocholic Acid Sodium Salt. Grades: Highly Purified. CAS No. 145-42-6,345909-26-4. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C??H??NO?SNa H2O, Molecular Weight: 555.7. US Biological Life Sciences.
Worldwide
Taurodeoxychloic Acid Sodium Salt
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling. Group: Biochemicals. Alternative Names: N-(3α,12α-Dihydroxy-5 β-cholan-24-oyl)-taurine Monosodium Salt; Taurodeoxycholic Acid Sodium Salt; Sodium 3α,12α-Dihydroxy-5 β-cholanoyltaurate; Sodium Deoxytaurocholate; Sodium Taurodeoxycholate; Sodium Taurodesoxycholate; Taurodeoxycholate Sodium. Grades: Highly Purified. CAS No. 1180-95-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ursocholic acid
Ursocholic acid, a bile acid present in mammalian bile, is converted to deoxycholic acid (UDC) by the mouse intestinal flora. Ursocholic acid acts as a gallstone dissolving agent in the liver through anti- apoptosis , anti-inflammatory, immunomodulatory, bile regulation, and coordinated changes in mitochondrial integrity and cell signaling, Ursocholic acid also has favorable effects on bones in patients with chronic cholestasis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 2955-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113212.
3α-hydroxy bile acid-CoA-ester 3-dehydrogenase
This bacterial enzyme is involved in the 7-dehydroxylation process associated with bile acid degradation. The enzyme has very little activity with unconjugated bile acid substrates. It has similar activity with choloyl-CoA, chenodeoxycholoyl-CoA, deoxycholoyl-CoA, and lithocholoyl-CoA. Group: Enzymes. Synonyms: baiA1 (gene name); baiA2 (gene name); baiA3 (gene name). Enzyme Commission Number: EC 1.1.1.395. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0315; 3α-hydroxy bile acid-CoA-ester 3-dehydrogenase; EC 1.1.1.395; baiA1 (gene name); baiA2 (gene name); baiA3 (gene name). Cat No: EXWM-0315.
5β-Cholanic acid-3α,12α-diol 3-acetate methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-acetyl methyldeoxycholate; Methyl 3alpha-acetoxy-12alpha-hydroxycholanate; 5beta-Cholanic acid-3alpha,12alpha-diol 3-acetate methyl ester; 3|A,12|A-Dihydroxy-5|A-cholan-24-oic acid methyl ester; methyl deoxycholate-3-acetate; 5|A-Cholanic acid-3|A,12|A-diol 3-acetate methyl ester; 3alpha,12alpha-Dihydroxy-5beta-cholan-24-oic acid methyl ester; Methyl 3|A-acetoxy-12|A-hydroxycholanate. Product Category: Steroidal Compounds. CAS No. 27240-83-1. Molecular formula: C27H44O5. Mole weight: 448.64. Purity: 0.95. IUPACName: methyl(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3-acetyloxy-12-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Canonical SMILES: CC(CCC(=O)OC)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)OC(=O)C)C)O)C. Density: 1.1g/cm³. Product ID: ACM27240831. Alfa Chemistry ISO 9001:2015 Certified.
bile acid CoA-transferase
The enzyme, characterized from the gut bacterium Clostridium scindens, catalyses the last step in bile acid 7α-dehydroxylation, the removal of the CoA moiety from the products. By using a transferase rather than hydrolase, the bacteria conserve the thioester bond energy, saving ATP molecules. Clostridium scindens possesses two forms of the enzyme, encoded by the baiF and baiK genes. While the enzymes have a broad acceptor specificity and can use allocholate, ursodeoxycholate, and β-muricholate, the donor specificity is more strict. BaiF acts on lithocholoyl-CoA and deoxycholoyl-CoA, and BaiK acts only on the latter. Group: Enzymes. Synonyms: baiF (gene name); baiK (gene name); bile acid coenzyme A transferase. Enzyme Commission Number: EC 2.8.3.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3421; bile acid CoA-transferase; EC 2.8.3.25; baiF (gene name); baiK (gene name); bile acid coenzyme A transferase. Cat No: EXWM-3421.
bile-salt sulfotransferase
The formation of sulfate esters of bile acids is an essential step in the prevention of toxicity by monohydroxy bile acids in many species. This enzyme is both a bile salt and a 3-hydroxysteroid sulfotransferase. In addition to the 5β-bile acid glycolithocholate, deoxycholate, 3β-hydroxy-5-cholenoate and dehydroepiandrosterone (3β-hydroxyandrost-5-en-17-one) also act as substrates [see also EC 2.8.2.2 (alcohol sulfotransferase) and EC 2.8.2.34 (glycochenodeoxycholate sulfotransferase)]. May be identical to EC 2.8.2.2. Group: Enzymes. Synonyms: BAST I; bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase; bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase; bile acid sulfotransferase I; glycolithocholate sulfotransferase. Enzyme Commission Number: EC 2.8.2.14. CAS No. 65802-92-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3372; bile-salt sulfotransferase; EC 2.8.2.14; 65802-92-8; BAST I; bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase; bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase; bile acid sulfotransferase I; glycolithocholate sulfotransferase. Cat No: EXWM-3372.
cholate-CoA ligase
Requires Mg2+ for activity. The mammalian enzyme is membrane-bound and catalyses the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates. The bacterial enzyme is soluble and participates in an anaerobic bile acid 7 α-dehydroxylation pathway. Group: Enzymes. Synonyms: BAL; bile acid CoA ligase; bile acid co. Enzyme Commission Number: EC 6.2.1.7. CAS No. 9027-90-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5709; cholate-CoA ligase; EC 6.2.1.7; 9027-90-1; BAL; bile acid CoA ligase; bile acid coenzyme A ligase; choloyl-CoA synthetase; choloyl coenzyme A synthetase; cholic thiokinase; cholate thiokinase; cholic acid:CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoyl coenzyme A synthetase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA synthetase; THCA-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate:CoA ligase (AMP-forming); cholyl-CoA synthetase; trihydroxycoprostanoyl-CoA synthetase. Cat No: EXWM-5709.
Sodium Deoxycholate, Monohydrate 99+%
Sodium deoxycholate monohydrate is a powerful solubilizing agent for estrogen synthetase. Used as a component in cell lysis buffers. Group: Biochemicals. Alternative Names: 3α,12.α-Dihydroxy-5 β-cholan-24-oic Acid Monohydrate; Desoxycholate; Desoxycholic Acid; NSC 681065; 3α,12α-Dihydroxy-5 β-cholanate; 7-Deoxycholate; Cholanoic acid; Kybella; Celluform Plus; Belkyra. Grades: Reagent Grade. CAS No. 145224-92-6. Pack Sizes: 25g, 100g, 250g, 1Kg. Molecular Formula: ?C24H39O4Na·H2O , Molecular Weight:?432.57. US Biological Life Sciences.
Worldwide
Taurochenodesoxycholic acid
Taurochenodesoxycholic acid - Product ID: NST-10-229. Category: Sterols. Alternative Names: 12-Deoxycholyltaurine, Chenodeoxycholyltaurine, Chenyltaurine. Purity: 98%. Test method: HPLC. CAS No. 516-35-8. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White Powder. Molecular formula: C26H45NO6S. Mole weight: 499.7. Storage: +2 +8 °C.
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