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Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DEXAMETHASONE 21-ACETATE; DexaMethasone 21-Acetate; 9α-Fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-Acetate; Dexamethasone Acetate. Product Category: Inhibitors. Appearance: White or almost white crystalline powder. CAS No. 1177-87-3. Molecular formula: C24H31FO6. Mole weight: 434.5. Purity: 0.99. IUPACName: Dexamethasone-17-acetate. Canonical SMILES: C[C@@]1([C@@]2(O)C(COC(C)=O)=O)[C@](C[C@H]2C)([H])[C@@](CCC3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C1. Density: 1.3 g/cm³. Product ID: ACM1177873. Alfa Chemistry ISO 9001:2015 Certified.
Dexamethasone acetate
Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexamethasone 21-acetate; Hexadecadrol acetate. CAS No. 1177-87-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-14648A.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardscovid-19 research and reference materialseuropean pharmacopoeia (ph. eur.)impurity standardspharmaceutical toxicologypharmacopoeial standards. Alternative Names: Dexamethasone Imp. G (EP),Betamethasone Acetate Imp. B (EP).
Dexamethasone Acetate EP Impurity B
Dexamethasone Acetate EP Impurity B is an impurity of Desoxymetasone which is an anti-inflammatory agent. Molecular formula: C24H31FO6. Mole weight: 434.50.
Dexamethasone Acetate EP Impurity C
Dexamethasone Acetate EP Impurity C is an impurity of Desoxymetasone which is an anti-inflammatory agent. Synonyms: 17-epi-Dexamethasone-21-acetate; 2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate. Molecular formula: C24H31FO6. Mole weight: 434.50.
Dexamethasone Acetate EP Impurity E
Dexamethasone Acetate EP Impurity E is an impurity of Desoxymetasone which is an anti-inflammatory agent. Synonyms: 2-((8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate. CAS No. 1524-94-3. Molecular formula: C24H33FO6. Mole weight: 436.51.
Dexamethasone Acetate EP Impurity E
Dexamethasone Acetate EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1524-94-3. Molecular formula: C24H33FO6. Mole weight: 436.52. Catalog: APB1524943.
Dexamethasone Acetate EP Impurity F
Dexamethasone Acetate EP Impurity F is an impurity of Desoxymetasone which is an anti-inflammatory agent. Uses: Dexamethasone intermediate. Synonyms: (9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-17-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione; 9,11β-Epoxy-17,21-dihydroxy-16α-methyl-9β-pregna-1,4-diene-3,20-dione; 21-O-Acetyl Dexamethasone 9,11-Epoxide. Grades: 98%. CAS No. 2884-51-7. Molecular formula: C24H30O6. Mole weight: 414.49.
Dexamethasone Acetate EP Impurity G
Desoximetasone Impurity G (Dexamethasone Acetate EP Impurity G) is an impurity of Desoxymetasone which is an anti-inflammatory agent. Synonyms: Desoximetasone Impurity G; 2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate. Grades: 96%. CAS No. 1597-78-0. Molecular formula: C24H31FO5. Mole weight: 418.50.
Dexamethasone 11,21-diacetate
Dexamethasone 11,21-diacetate is an impurity of Desoxymetasone which is an anti-inflammatory agent. Synonyms: (11β,16α)-1,21-bis(acetyloxy)-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione. Grades: 97%. CAS No. 3949-26-6. Molecular formula: C26H33FO7. Mole weight: 476.53.
Dexamethasone-17-acetate
Cas No. 1177-87-3.
Dexamethasone-17-acetate
Dexamethasone-17-acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Decadronal. Appearance: White solid. CAS No. 1177-87-3. Molecular formula: C24H31FO6. Mole weight: 434.5. Purity: 0.99. IUPACName: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate. Canonical SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)O)C)O)F)C. Product ID: ACM1177873-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Dexomethasone.
Dexamethasone 21-acetate
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C24H31FO6. CAS No. 1177-87-3. Prepack ID 90027040-1g. Molecular Weight 434.5. See USA prepack pricing.
Dexamethasone 21-acetate
?99%. Group: Fluorescence/luminescence spectroscopypharma & vet compounds & metabolitespharma & vet compounds & metabolites. Alternative Names: Dexamethasone Imp. G (EP),Betamethasone Acetate Imp. B (EP).
21-O-Acetyl 6β-Hydroxy Dexamethasone
21-O-Acetyl 6β-Hydroxy Dexamethasone is a protected metabolite of Dexamethasone, which is a glucocorticoid used as an anti-inflammatory agent. Synonyms: (6β,11β,16α)-9-Fluoro-6,11,17-trihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate; Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-6,11,17-trihydroxy-16-methyl-, (6β,11β,16α)-. Grades: ≥90%. CAS No. 72559-77-4. Molecular formula: C24H31FO7. Mole weight: 450.50.
21-O-Acetyl Dexamethasone
Protected Dexamethasone, a glucocorticoid anti-inflammatory agent. Group: Biochemicals. Alternative Names: (11 β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; 9-Fluoro-11 β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione 21-Acetate; Decadronal; Dectancyl; Dex-Cortidelt Acetate; Dexa-Cortisyl; NSC 39471. Grades: Highly Purified. CAS No. 1177-87-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
7,4'-Dihydroxyflavone
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor ( IC 50 =0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)?paradoxical adverse effects on eotaxin production [1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC 50 value of 1.4 μM [1]. Uses: Scientific research. Group: Natural products. CAS No. 2196-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2609.
Betamethasone acetate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardscovid-19 research and reference materialseuropean pharmacopoeia (ph. eur.)impurity standardspharmaceutical toxicologypharmacopoeial standards. Alternative Names: Dexamethasone Acetate Imp. D (EP), 9-Fluoro-11beta,17-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-21-yl Acetate, 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate, Betamethasone 21-acetate, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16beta-methyl-, 21-acetate (6CI,7CI,8CI), 21-Acetoxy-9alpha-fluoro-11beta,17alpha-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione, Betamethasone acetate,Betamethasone Acetate, (11beta,16beta)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione.
Dexamethasone EP Impurity H
Dexamethasone EP Impurity H is an impurity of Desoxymetasone which is an anti-inflammatory agent. Synonyms: 2-((8S,10S,13S,14S,16R,17R)-17-Hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate. CAS No. 10106-41-9. Molecular formula: C24H30O5. Mole weight: 398.49.
Dexamethasone EP Impurity H
Dexamethasone EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((8S,10S,13S,14S,16R,17R)-17-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate. CAS No. 10106-41-9. Molecular formula: C24H30O5. Mole weight: 398.49. Catalog: APB10106419.
Paramethasone Acetate
Paramethasone Acetate, a derivative of dexamethasone, has been found to be a glucocorticoid drug and could be used in some inflammatory diseases. Synonyms: (6α,11β,16α)-21-(Acetyloxy)-6-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 16α-Methyl-6α-fluoroprednisolone 21-acetate; 21-Acetyl-6α-fluoro-16α-methylprednisolone; 6α-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Acetate; Alondra; Cortidene; Dilar; Dillar; Flumethone; Haldrate; Haldrone; Metilar; Monocortin; Paramethasone 21-acetate; Paramethasone Acetate; Paramezone; Stemex; Syntecort. Grades: 98%. CAS No. 1597-82-6. Molecular formula: C24H31FO6. Mole weight: 434.50.
(16 β)-17,21-Bis(acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione is an intermediate in the synthesis of (16 β)-17,21-Dihydroxy-16 β-methyl-pregna-1,4,9(11)-triene-3,20-dione which is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient. Group: Biochemicals. Grades: Highly Purified. CAS No. 65535-36-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C26H32O6. US Biological Life Sciences.
Worldwide
21-O-Acetyl 6 β-Hydroxy Dexamethasone
Protected metabolite of Dexamethasone. Group: Biochemicals. Alternative Names: (6 β,11 β,16α)-21-(Acetyloxy)-9-fluoro-6,11,17-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione. Grades: Highly Purified. CAS No. 72559-77-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
21-O-Acetyl dexamethasone 9,11-epoxide
21-O-Acetyl dexamethasone 9,11-epoxide. Group: Biochemicals. Alternative Names: (9b,11b,16a)-21-(Acetyloxy)-9,11-epoxy-17-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione; 9,11b-Epoxy-17,21-dihydroxy-16a-methyl-9b-pregna-1,4-diene-3,20-dione. Grades: Highly Purified. CAS No. 2884-51-7. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C24H30O6. US Biological Life Sciences.
Worldwide
21-O-Acetyl Dexamethasone-d5
Isotope labelled intermediate in the synthesis of Dexamethasone (D298800), a glucocorticoid anti-inflammatory agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H26D5FO6. US Biological Life Sciences.
Worldwide
21-O-Acetyl Dexamethasone-d5 9,11-Epoxide
Labeled Dexamethasone intermediate. Group: Biochemicals. Alternative Names: (9 β,11 β,16α)-21-(Acetyloxy)-9,11-epoxy-17-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione-d5; 9,11 β-Epoxy-17,21-dihydroxy-16α-methyl-9 β-pregna-1,4-diene-3,20-dione-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Dexamethasone Impurity 1
Dexamethasone Impurity 1 is an impurity of Desoxymetasone which is an anti-inflammatory agent. Synonyms: 1879-77-2; (8S,9R,10S,11S,13S,14S,16R,17R)-17-Acetyl-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; CHEMBL2104352; SCHEMBL11328085; DTXSID201314703; (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione21-Deoxydexamethasone. CAS No. 426-15-3. Molecular formula: C22H29FO4. Mole weight: 376.46.
Fluocinolone acetonide
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It was also found to strongly potentiate TGF-β-associated chondrogenesis of bone marrow mesenchymal stem/progenitor cells, by increasing the levels of collagen type II by more than 100 fold compared to the widely used dexamethasone. Uses: Glucocorticoids, synthetic; glucocorticoids, topical. Synonyms: Isepamicine (Isepamycin, sch21420) Sulphate. Grades: >98%. CAS No. 67-73-2. Molecular formula: C24H30F2O6. Mole weight: 452.488.
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