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2',3'-Dideoxy-2',2'-difluorocytidinea potent antiviral agentfinds clinical application in the management of HIV and hepatitis B virus (HBV) infections. By impeding the reverse transcriptase enzyme, it effectively hampers viral replication. This nucleoside analogue demonstrates a remarkable affinity for viral polymerases, ensuring minimal toxicity to host cells. Synonyms: 4-amino-1-((2R,5S)-3,3-difluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. CAS No. 124708-94-7. Molecular formula: C9H11F2N3O3. Mole weight: 247.20.
2',3'-Dideoxy-3',5-difluorocytidine
2',3'-Dideoxy-3',5-difluorocytidine is a potent antiviral drug used in the treatment of HIV and AIDS. It inhibits the reverse transcriptase enzyme, preventing the conversion of viral RNA to DNA. This drug is an effective option for patients with viral resistance to other antivirals, offering hope in managing these infections effectively. Synonyms: 4-amino-5-fluoro-1-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. CAS No. 134379-78-5. Molecular formula: C9H11F2N3O3. Mole weight: 247.20.
2'-Deoxy-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine. Group: Biochemicals. Alternative Names: Gemcitabine base; 4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one. Grades: Highly Purified. CAS No. 95058-81-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C9H11F2N3O4. US Biological Life Sciences.
2'-Deoxy-2',2'-difluorocytidine 5'-(4-Methylbenzenesulfonate) is an intermediate in the synthesis of Gemcitabine metabolites. CAS No. 1151528-53-8. Molecular formula: C16H17F2N3O6S. Mole weight: 417.38.
2-Deoxy-2,2-difluorocytidine 5- (4-Methyl Benzene sulfonate) is an intermediate in the synthesis of Gemcitabine (G305000) metabolites. Group: Biochemicals. Grades: Highly Purified. CAS No. 1151528-53-8. Pack Sizes: 1mg, 10mg. Molecular Formula: C16H17F2N3O6S. US Biological Life Sciences.
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2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate triethylammonium salt
2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate triethylammonium salt. Group: Biochemicals. Alternative Names: Gemcitabine 5'-monophosphate triethylammonium salt. Grades: Highly Purified. Pack Sizes: 2mg, 5mg, 10mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium salt
A ( β-anomer) intermediate of Gemcitabine; antitumor compound. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluoro-3,5-bis-O-benzoylcytidine. Grades: Highly Purified. CAS No. 134790-39-9. Pack Sizes: 100mg. US Biological Life Sciences.
A labelled ( β-anomer) intermediate of Gemcitabine; antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 1267650-42-9. Pack Sizes: 1mg. US Biological Life Sciences.
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2'-Deoxy-5-chloro-2',2'-difluorocytidine
2'-Deoxy-5-chloro-2',2'-difluorocytidine, a vital compound in the field of biomedicine, holds immense significance. Falling under the category of nucleoside analogs, it finds extensive application in the treatment of a diverse array of ailments such as viral infections and cancer. Exhibiting its prowess as an antiviral and antitumor agent, this compound effectively thwarts viral DNA replication and disrupts DNA synthesis within cancer cells. CAS No. 132786-39-1. Molecular formula: C9H10ClF2N3O4. Mole weight: 297.64.
2'-Deoxy-5'-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2', 2'-difluorocytidine is an intermediate in the synthesis of Gemcitabine (G305000) metabolites. Group: Biochemicals. Grades: Highly Purified. CAS No. 1151528-36-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H25F2N3O4Si. US Biological Life Sciences.
2'-Deoxy-5'-O-[(1, 1-dimethylethyl)dimethylsilyl]-2', 2'-difluorocytidine is an intermediate in the synthesis of Gemcitabine metabolites. Synonyms: 4-amino-1-((2R,4R,5R)-5-((tert-butyldimethylsilyloxy)methyl)-3,3-difluoro-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-amino-1-[(2R,4R,5R)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,3-difluoro-4-hydroxyoxolan-2-yl]pyrimidin-2-one; 2'-Deoxy-5'-O-[(1, 1-dimethylethyl)dimethylsilyl]-2', 2'-difluorocytidine; 5'-O-(t-butyldimethylsilyl)-2'-deoxy-2',2'-difluorocytidine; 4-Amino-1-((2R,4R,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-3,3-difluoro-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one. CAS No. 1151528-36-7. Molecular formula: C15H25F2N3O4Si. Mole weight: 377.46.
3',5'-Di-O-benzoyl-2'-deoxy-2',2'-difluorocytidine. Group: Biochemicals. Alternative Names: 2',2'-Difluoro-3',5'-dibenzoyl-2'-deoxycytidine. Grades: Highly Purified. CAS No. 134790-39-9. Pack Sizes: 1g, 2g, 5g, 10g. Molecular Formula: C23H19F2N3O6. US Biological Life Sciences.
Worldwide
3'-Deoxy-3',5-difluorocytidine
3'-Deoxy-3',5-difluorocytidine is an exceptional antiviral compound, playing a paramount role in research of distinct viral ailments like hepatitis C and herpes simplex. By intricately obstructing the compoundion of viral nucleic acids, it remarkably impedes viral replication. Synonyms: 4-amino-5-fluoro-1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 661470-65-1. Molecular formula: C9H11F2N3O4. Mole weight: 263.20.
4'-?C-Azido-?2'-?deoxy-?2',?2'-?difluorocytidine
4'-C-Azido-2'-deoxy-2',2'-difluorocytidine, a vital compound extensively employed in the biomedical sector, emerges as a paramount entity. Renowned for its remarkable antiviral attributes, it takes center stage in combatting diverse viral infections, such as hepatitis B and HIV. Its potent capability to impede viral replication endows it with immense value, positioning it as an invaluable asset in antiviral therapies. Synonyms: 4-amino-1-[(2R,4R,5R)-5-azido-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one; 4'-c-azido-2'-deoxy-2',2'-difluorocytidine. CAS No. 1145869-51-7. Molecular formula: C9H10F2N6O4. Mole weight: 304.21.
5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine
5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine, a potent antiviral chemical engineered to fight hepatitis B and C, operates by hindering viral DNA reproduction, hindering the spread of viruses in the body. Sharing similarities with antiviral drugs such as lamivudine and entecavir, this sophisticated molecule boasts a unique chemical structure, enabling it to tackle specific strains with heightened efficacy. As noted through clinical trials, this chemical has exhibited encouraging performance, further cementing its reputation as a viable option in chronic viral infection treatment. Synonyms: 5'-O-Acetylgemcitabine. Grades: 98%. Molecular formula: C11H13F2N3O5. Mole weight: 305.23.
5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine
5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine. Group: Biochemicals. Alternative Names: 5'-O-Acetylgemcitabine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Labeled Gemcitabine, an antineoplastic. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine-13C,15N2 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Gemcitabine is a nucleoside analog of deoxycytidine used as chemotherapy to treat patients with various types of cancer. After passage through the cell membrane via nucleoside transporters, gemcitabine undergoes complex intracellular conversion to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). dFdCTP inhibits DNA polymerase by competing with deoxycytidine triphosphate (dCTP). dFdCDP inhibits ribonucleoside reductase and DNA synthesis by causing depletion of deoxyribonucleotide pools, and thus potentiating the effects of dFdCTP. Gemcitabine can be inactivated to 2,2'-difluorodeoxyuridine, mainly by deoxycytidine deaminase. Also, 5'-nucleotidase catalyses the conversion of nucleotides to nucleosides and inhibits nucleoside kinases. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine Hydrochloride, dFdC, dFdCyd. Grades: Highly Purified. CAS No. 122111-03-9. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences.
N4-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluorocytidine is an invaluable antiviral compound renowned in the biomedical realm, aiding in studying DNA viruses like herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its efficacy stems from its exceptional chemical composition, which selectively targets viral DNA synthesis, thereby thwarting their proliferation. Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2',2'-difluoro-. Grades: ≥95%. CAS No. 142808-43-3. Molecular formula: C37H33F2N3O7. Mole weight: 669.67.
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite is an indispensable compound within the biomedical domain with widespread application as a phosphoramidite constituent during oligonucleotide synthesis, primarily in the research of antisense therapy and gene silencing. Synonyms: DMTr-2',2'-difluoro-dC(Bz)-3'-CED-phosphoramidite; Gemcitabine amidite; Gemcitabine 3'-CE phosporamidite; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine 3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N4-Benzoyl-2',2'-difluoro-2'-deoxycytidine 3'-CE phosphoramidite; 5'-DMT-N4-Bz-2',2'-difluoro-dC 3'-CE phosphoramidite. Grades: ≥95%. CAS No. 142808-44-4. Molecular formula: C46H50F2N5O8P. Mole weight: 869.89.
N-Acetyl-2'-deoxy-2',2'-difluorocytidine
N-Acetyl-2'-deoxy-2',2'-difluorocytidine is an astounding compound with efficacious potential, considered a formidable tool for its remarkable antiviral attributes. It vehemently studys an extensive array of viral afflictions encompassing respiratory syncytial virus (RSV), influenza and hepatitis C virus (HCV). Synonyms: N-Acetyl-2'-deoxy-2',2'-difluorocytidine; Z2904061907; N-[1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide. CAS No. 1026184-06-4. Molecular formula: C11H13F2N3O5. Mole weight: 305.23.
N-Benzoyl-2'-deoxy-2',2'-difluorocytidine
N-Benzoyl-2'-deoxy-2',2'-difluorocytidine is a potent antiviral compound used in the research of viral infections such as herpesviruses and poxviruses. With unique structure, this compound inhibits viral reproduction by interfering with viral DNA synthesis. Synonyms: N6-Benzoyl-2'-deoxy-2',2'-diflurocytidine; 4-N-benzoylgemcitabine; N4-benzoyl-2'-deoxy-2',2'-difluorocytidine; N-Bz-Gemcitabine. Grades: ≥95%. CAS No. 142816-70-4. Molecular formula: C16H15F2N3O5. Mole weight: 367.30.
N-Benzoyl-2'-deoxy-2',2'-difluorocytidine 3'-Benzoate is an intermediate in the synthesis of Gemcitabine metabolites. Grades: 96%. CAS No. 1020657-43-5. Molecular formula: C23H19F2N3O6. Mole weight: 471.41.
N-Benzoyl-2'-deoxy-2',2'-difluorocytidine 3'-Benzoate 5'-(4-Methylbenzenesulfonate) is an intermediate in the synthesis of Gemcitabine metabolites. CAS No. 1151528-38-9. Molecular formula: C30H25F2N3O8S. Mole weight: 625.6.
N-Benzoyl-2'-deoxy-5'-O-[(1, 1-dimethylethyl)dimethylsilyl]-2', 2'-difluorocytidine 3'-Benzoate is an intermediate in the synthesis of Gemcitabine metabolites. CAS No. 1151528-37-8. Molecular formula: C29H33F2N3O6Si. Mole weight: 585.67.
A diphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as an inhibitor of ribonucleotide reductases (RNRs). Synonyms: 2'-deoxy-2',2'-difluorocytidine 5'-(trihydrogen diphosphate). Grades: ≥ 95 % by HPLC. CAS No. 116371-66-5. Molecular formula: C9H13F2N3O10P2. Mole weight: 423.16.
Gemcitabine 5'-elaidate
Gemcitabine 5'-elaidate. Group: Biochemicals. Alternative Names: (E)-((2R,3R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate; 2'-Deoxy-2',2'-difluorocytidine 5'-(9E)-9-octadecenoate; CP-4126; LVT derivative of Gemcitabine; CO-101. Grades: Highly Purified. CAS No. 210829-30-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C27H43F2N3O5. US Biological Life Sciences.
Worldwide
Gemcitabine-5'-triphosphate
A triphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Synonyms: 2',2'-Difluorocytidine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C9H14N3O13P3F2. Mole weight: 503.14.
Gemcitabine Diphosphate Ammonium Salt
Gemcitabine Diphosphate is a phosphorylated metabolite of Gemcitabine, an antineoplastic agent. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine 5-(Trihydrogen Diphosphate) Triethylamine Salt; Gemcitabine 5-Diphosphate Triethylamine Salt. Grades: Highly Purified. CAS No. free acid: 116371-66-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Diphosphate Triethylamine Salt (>90%)
Gemcitabine Diphosphate is a Gemcitabine phosphorylated metabolite, an antineoplastic agent. Synonyms: 2'-Deoxy-2',2'-difluorocytidine 5'-(Trihydrogen Diphosphate) Triethylamine Salt; Gemcitabine 5'-Diphosphate Triethylamine Salt. Grades: 90%. Molecular formula: C27H58F2N6O10P2. Mole weight: 726.73.
Gemcitabine Triphosphate Ditriethylamine
Gemcitabine Triphosphate is a Gemcitabine phosphorylated metabolite, an antineoplastic agent. Synonyms: 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) Di(N,N-diethylethanamine). Grades: 97%. Molecular formula: C21H44F2N5O13P2. Mole weight: 705.52.
Gemcitabine Triphosphate Ditriethylamine
Gemcitabine Triphosphate is a phosphorylated metabolite of Gemcitabine , an antineoplastic agent. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) Di(N,N-diethylethanamine). Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Triphosphate (triethylammonium salt form)
An impurity of Gemcitabine. Gemcitabine is an antineoplastic chemotherapy medication of the antimetabolites class. It halts cell division through damaging RNA or DNA which control the process. It can be used to treat multiple cancers. Synonyms: 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) triethylammonium. Grades: 95%. CAS No. 1035495-84-1. Molecular formula: C33H74F2N7O13P3. Mole weight: 907.9.
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