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1-(2,2-Difluoroethyl)-1H-pyrazol-4-amine acts as a reagent for the development of pyrimidine derivatives as JAK3 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1006333-08-9. Pack Sizes: 25mg, 100mg. Molecular Formula: C5H7F2N3, Molecular Weight: 147.13. US Biological Life Sciences.
1,3,2-Dioxaborolane, 2-[4-(1,1-difluoroethyl)phenyl]-4,4,5,5-tetramethyl-. Group: Biochemicals. Grades: Highly Purified. CAS No. 1000994-94-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H19BF2O2, Molecular Weight: 268.11. US Biological Life Sciences.
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1-Bromo-2-(1,1-difluoroethyl)benzene
1-Bromo-2-(1,1-difluoroethyl)benzene. Uses: Designed for use in research and industrial production. Product Category: Aryl. CAS No. 444581-46-8. Molecular formula: C7H6BrCl. Mole weight: 221.04. Product ID: ACM444581468. Alfa Chemistry ISO 9001:2015 Certified.
1-Bromo-3-(1,1-difluoroethyl)benzene
1-Bromo-3-(1,1-difluoroethyl)benzene. Uses: Designed for use in research and industrial production. Product Category: Aryl Fluorinated Building Blocks. CAS No. 445303-70-8. Molecular formula: C6H4FNO5S. Mole weight: 221.04. Product ID: ACM445303708-1. Alfa Chemistry ISO 9001:2015 Certified.
2,2-Difluoroethylamine hydrochloride
2,2-Difluoroethylamine hydrochloride. Group: Biochemicals. Alternative Names: 2,2-Difluoro-1-ethanamine hydrochloride. Grades: Highly Purified. CAS No. 79667-91-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C2H6ClF2N. US Biological Life Sciences.
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2,2-Difluoroethylamine hydrochloride
2,2-Difluoroethylamine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 79667-91-7, 2,2-difluoroethanamine hydrochloride, 2,2-Difluoroethylamine hydrochloride, AGN-PC-01UT6A, CTK5E7002, MolPort-001-778-515, 2,2-Difluoroethylaminehydrochloride, PC9627, AKOS007930501, AG-L-24491, MCULE-9437628707, Ethanamine, 2,2-difluoro-, hydrochloride, KB-87255, 2,2-bis(fluoranyl)ethanamine hydrochloride, FT-0666830, Ethanamine,2,2-difluoro-, hydrochloride (9CI), A839733, I05-1735. Product Category: Amines. CAS No. 79667-91-7. Molecular formula: C2H6ClF2N. Mole weight: 117.53. Purity: 0.96. IUPACName: 2,2-difluoroethanamine;hydrochloride. Canonical SMILES: C(C(F)F)N.Cl. Product ID: ACM79667917. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2,2-difluoroethan-1-amine hydrochloride.
2,2-Difluoroethyl Triflate is used to prepare kinesin spindle protein inhibitors for treatment of taxane-refractory cancer. It is also used to synthesize MexAB-?OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Group: Biochemicals. Grades: Highly Purified. CAS No. 74427-22-8. Pack Sizes: 1g, 5g. Molecular Formula: C3H3F5O3S, Molecular Weight: 214.11. US Biological Life Sciences.
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(2-Bromo-1,1-difluoroethyl)benzene
(2-Bromo-1,1-difluoroethyl)benzene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2-bromo-1,1-difluoroethyl)benzene, 108661-89-8, 1-(2-bromo-1,1-difluoroethyl)benzene, SBB070808, AG-D-25174, Benzene,(2-bromo-1,1-difluoroethyl)-, zlchem 601, ACMC-20aggi, PubChem10047, AGN-PC-00NKBY, SureCN2281974, CTK4A6130, ZLD0048, MolPort-001-773-349, ACT05824, 2-Bromo-1,1-(difluoroethyl)benzene, ANW-72256, RW3380, ZINC54967619, (2-Bromo-1,1-difluoroethyl)benzene. Product Category: Bromine Series. Appearance: cream. CAS No. 108661-89-8. Molecular formula: C8H7 Br F2. Mole weight: 221.04. Purity: 0.96. IUPACName: (2-bromo-1,1-difluoroethyl)benzene. Canonical SMILES: C1=CC=C(C=C1)C(CBr)(F)F. Density: 1.222g/cm³. Product ID: ACM108661898. Alfa Chemistry ISO 9001:2015 Certified.
Bis(2,2-difluoroethyl)ether. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BIS(2,2-DIFLUOROETHYL)ETHER. Product Category: Heterocyclic Organic Compound. CAS No. 69948-35-2. Molecular formula: C4H6F4O. Mole weight: 146.0835. Purity: 0.96. IUPACName: bis-(2,2-difluoro-ethyl) ether. Product ID: ACM69948352. Alfa Chemistry ISO 9001:2015 Certified.
Chlorotrifluoroethylene-1,1-difluoroethylene copolymer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1-Difluoroethene compound with 1-chloro-1,2,2-trifluoroethene (1:1). Product Category: Promotional Products. Appearance: solid. CAS No. 9010-75-7. Purity: F 25%. Product ID: ACM9010757-1. Alfa Chemistry ISO 9001:2015 Certified.
trans-4,5-Difluoroethylenecarbonate
trans-4,5-Difluoroethylenecarbonate (CAS# 311810-76-1 ) is a useful research chemical. Synonyms: 4alpha,5beta-Difluoro-1,3-dioxolane-2-one; 1,3-Dioxolan-2-one, 4,5-difluoro-, (4R,5R)-rel-; rel-(4R,5R)-4,5-difluoro-1,3-dioxolan-2-one; trans-4,5-difluoro-1,3-dioxolan-2-one; trans-difluoroethylene carbonate. Grades: 98 %. CAS No. 311810-76-1. Molecular formula: C3H2F2O3. Mole weight: 124.04.
1-BROMO-4-(2,2-DIFLUOROVINYL)BENZENE
1-BROMO-4-(2,2-DIFLUOROVINYL)BENZENE. Group: Monomers. Alternative Names: 2-(4-BROMOPHENYL)-1,1-DIFLUOROETHYLENE; 1-BROMO-4-(2,2-DIFLUOROVINYL)BENZENE; 4-BROMO-BETA,BETA-DIFLUOROSTYRENE; 4-Bromo-β,β-difluorostyrene (stabilized with TBC); 4-Bromo-beta,beta-difluorostyrene (stabilized with TBC). CAS No. 84750-93-6. Product ID: 1-bromo-4-(2,2-difluoroethenyl)benzene. Molecular formula: 219.03. Mole weight: C8H5BrF2. C1=CC(=CC=C1C=C(F)F)Br. LXJISEJYMAHRKE-UHFFFAOYSA-N. 96%.
3-(1,1-Difluoro-ethyl)-pyridine
3-(1,1-Difluoro-ethyl)-pyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(1,1-difluoroethyl)pyridine, 2,2-Difluoro-2-(3-pyridyl)ethane, AC1LD0RW, MolPort-004-757-686, pyridine, 3-(1,1-difluoroethyl)-, AKOS005258047, FT-0686160, InChI=1/C7H7F2N/c1-7(8,9)6-3-2-4-10-5-6/h2-5H,1H, 114468-03-0. Product Category: Heterocyclic Organic Compound. CAS No. 114468-03-0. Molecular formula: C7H7F2N. Mole weight: 143.133986 [g/mol]. Purity: 0.96. IUPACName: 3-(1,1-difluoroethyl)pyridine. Canonical SMILES: CC(C1=CN=CC=C1)(F)F. Product ID: ACM114468030. Alfa Chemistry ISO 9001:2015 Certified.
4-(2,2-Difluoro-ethylamino)-piperidine-1-carboxylic acid tert-butyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-(2,2-DIFLUORO-ETHYLAMINO)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, 1010422-66-8, CTK3J9495, MolPort-004-968-904, AKOS015969143, AG-D-07292. Product Category: Heterocyclic Organic Compound. CAS No. 1010422-66-8. Molecular formula: C12H22F2N2O2. Mole weight: 264.31. Purity: 0.96. IUPACName: tert-butyl 4-(2,2-difluoroethylamino)piperidine-1-carboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CCC(CC1)NCC(F)F. Product ID: ACM1010422668. Alfa Chemistry ISO 9001:2015 Certified.
4-Bromo-β,β-difluorostyrene (stabilized with TBC)
4-Bromo-β,β-difluorostyrene (stabilized with TBC). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Bromo-4-(2,2-difluorovinyl)benzene (stabilized with TBC); 2-(4-Bromophenyl)-1,1-difluoroethylene (stabilized with TBC). Product Category: Styrene Monomers. Appearance: Colorless to Yellow Clear Liquid. CAS No. 84750-93-6. Molecular formula: C8H5BrF2. Mole weight: 219.03 g/mol. Purity: 98.0%(GC). Product ID: ACM-MO-84750936. Alfa Chemistry ISO 9001:2015 Certified.
AZ0108
AZ0108 is an orally bioavailable, PARP1,2,6 inhibitor that causes a multi-polar spindle phenotype at double digit nM concentrations. AZ0108 has been utilized as in vitro tools and in vivo probes to investigate the biological consequences of inhibiting centrosome clustering through PARP enzymes. Synonyms: (S) -4- ( (3- (3- (1, 1-difluoroethyl) -6-methyl-5, 6, 7, 8-tetrahydro-[1, 2, 4]triazolo[4, 3-a]pyrazine-7-carbonyl) phenyl) difluoromethyl) phthalazin-1 (2H) -one; AZ0108; AZ-0108; AZ 0108. Grades: >98%. CAS No. 1825345-52-5. Molecular formula: C24H20F4N6O2. Mole weight: 500.45.
DSM265
DSM265 is a selective DHODH (dihydroorotate dehydrogenase) inhibitor used for prevention and treatment of malaria. DSM265 is highly selective toward DHODH of the malaria parasite Plasmodium. It is efficacious against both blood and liver stages of P. falciparum and active against drug-resistant parasite isolates. Treatment for malaria was in phase II clinical trials. Uses: Malaria. Synonyms: DSM265; DSM-265; DSM 265; UNII-0Q42P4YI6B; 0Q42P4YI6B; CHEMBL1956285; SCHEMBL14053411;2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-$l^{6}-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine. Grades: 98%. CAS No. 1282041-94-4. Molecular formula: C14H12F7N5S. Mole weight: 415.34.
Flupyradifurone
Flupyradifurone. Group: Biochemicals. Alternative Names: 4-[[(6-Chloro-3-pyridinyl)methyl](2,2-difluoroethyl)amino]-2(5H)-furanone; 4-[[ (6-Chloropyridin-3-yl) methyl] (2, 2-difluoroethyl) amino]furan-2 (5H) -one. Grades: Highly Purified. CAS No. 951659-40-8. Pack Sizes: 10mg. Molecular Formula: C12H11ClF2N2O2, Molecular Weight: 288.68. US Biological Life Sciences.
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LSZ102
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50=0.2 nM. LSZ102 demonstrated IC50 for MCF-7 cells=1.7 nM. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LSZ102; LSZ-102; LSZ 102; SERD LSZ102; SERD LSZ-102; SERD LSZ 102. Product Category: Antagonists. Appearance: Solid powder. CAS No. 2135600-76-7. Molecular formula: C25H17F3O4S. Mole weight: 470.46. Purity: >98%. IUPACName: (E) -3- (4-((2-(2- (1,1-Difluoroethyl)-4-fluorophenyl)-6-hydroxybenzo[b]thiophen-3-yl)oxy)phenyl)acrylic Acid. Canonical SMILES: O=C(O)/C=C/C1=CC=C(OC2=C(C3=CC=C(F)C=C3C(F)(F)C)SC4=CC(O)=CC=C42)C=C1. Product ID: ACM2135600767. Alfa Chemistry ISO 9001:2015 Certified.
NVS-PAK1-1
NVS-PAK1-1 is potent and specific allosteric PAK1 inhibitor (IC50 = 5 nM) with selective over PAK2 and a panel of 442 kinases. Synonyms: NVS-PAK1-1; NVSPAK11; NVS PAK1 1; (3S)-3-[[8-chloro-11-(2,2-difluoroethyl)-3-fluorobenzo[b][1,4]benzodiazepin-6-yl]amino]-N-propan-2-ylpyrrolidine-1-carboxamide. CAS No. 1783816-74-9. Molecular formula: C23H25ClF3N5O. Mole weight: 479.93.
NVS PAK1 C
NVS PAK1 C is the negative control of NVS PAK1 1. NVS PAK1 1 is a potent and selective PAK1 inhibitor (IC50 = 5 nM). Selective for PAK1 over PAK2 and a panel of 442 kinases. Synonyms: (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide. Grades: ≥98% by HPLC. CAS No. 2250019-95-3. Molecular formula: C22H23ClF3N5O. Mole weight: 465.91.
PF-04880594
PF-04880594 is a RAF inhibitor, which induces ERK phosphorylation and RAF dimerization in those epithelial tissues that undergo hyperplasia. PF-04880594 stimulates production of the inflammatory cytokine interleukin 8 in HL-60 cells. Synonyms: PF04880594; PF 04880594; 3-((4-(1-(2,2-difluoroethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propanenitrile. CAS No. 1111636-35-1. Molecular formula: C19H16F2N8. Mole weight: 394.39.
Poly(vinylidene fluoride), average Mw ~534,000, powder
1,1-Difluoroethylene (or vinylidene fluoride) is a colorless gas which is flammable in the ranges of 5.5 to 21%. It is toxic by inhalation and contact. It is slightly soluble in water and soluble in alcohol and ether. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket.;GasVapor;COLOURLESS COMPRESSED LIQUEFIED GAS WITH CHARACTERISTIC ODOUR.;Colorless gas with a faint, ethereal odor.;Colorless gas with a faint, ethereal odor. [Note: Shipped as a liquefied compressed gas.]. Group: Polymers. CAS No. 24937-79-9. Product ID: 1,1-difluoroethene. Molecular formula: 64.03g/mol. Mole weight: C2H2F2;CH2=CF2;C2H2F2. C=C(F)F. InChI=1S/C2H2F2/c1-2(3)4/h1H2. BQCIDUSAKPWEOX-UHFFFAOYSA-N.
Vinflunine Ditartrate
Vinflunine is a semisynthetic Vinca alkaloid with microtubule destabilizing and antiangiogenic activity. Vinflunine is a derivative of Vinorelbine. Vinflunine is used as an antineoplastic. Group: Biochemicals. Alternative Names: (2 β,3 β,4 β,5α,12 β,19α)-4-(Acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic Acid Methyl Ester (2R,3R)-2,3-Dihydroxybutanedioate; 4'-Deoxy-20',20'-difluoro-5'-nor-vincaleukoblastine Ditartrate; 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate; BMS 710485; F 12158; Javlor. Grades: Highly Purified. CAS No. 194468-36-5. Pack Sizes: 5mg. US Biological Life Sciences.
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