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Protected labeled Biopterin. A pteridine widely distributed in nature; naturally occurring as the L-erythro-form. Considered as a growth factor for some insects. Fluoresces with a blue color in alkaline solution. Group: Biochemicals. Grades: Highly Purified. CAS No. 1346597-41-8. Pack Sizes: 500ug. US Biological Life Sciences.
A natural cofactor for phenyl. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydro-biopterin, Dihydrochloride, 6R-BH4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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7,8-dihydrobiopterin
7,8-dihydrobiopterin is a precursor of BH4 synthesis and a noncompetitive inhibitor of GCH-I (GTP cyclohydrolase I). It is the reduced form of Biopterin. Synonyms: 7,8-Dihydro-L-biopterin; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone; L-erythro-7,8-Dihydrobiopterin; L-erythro-Dihydrobiopterin. Grades: > 95%. CAS No. 6779-87-9. Molecular formula: C9H13N5O3. Mole weight: 239.24.
7,8-Dihydro-biopterin
7,8-Dihydro-biopterin. Group: Biochemicals. Grades: Highly Purified. CAS No. 6779-87-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H13N5O3. US Biological Life Sciences.
Worldwide
7,8-Dihydro-L-biopterin
7,8-Dihydro-L-biopterin is an oxidation product of tetrahydrobiopterin. Uses: Scientific research. Group: Natural products. CAS No. 6779-87-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008646.
7,8-Dihydro-L-biopterin
7,8-dihydro-L-Biopterin is a precursor of BH4 synthesis and a noncompetitive inhibitor of GCH-I (GTP cyclohydrolase I), with a Ki of 14.4 μM. Applications: A precursor of bh4 synthesis. Group: Coenzymes. Synonyms: BH2; Dihydrobiopterin; Quinonoid dihydrobiopterin. CAS No. 6779-87-9. Purity: ≥98%. Mole weight: 239.23. Appearance: Powder. Form: Solid. BH2; Dihydrobiopterin; Quinonoid dihydrobiopterin; 7,8-Dihydro-L-biopterin; 6779-87-9. Cat No: COEC-066.
An oxidation producct of tetrahydrob. Group: Biochemicals. Alternative Names: 2-Amino-6-(1,2-dihydroxy-propyl)-7,8-dihydro-3H-pteridin-4-one. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
7,8-Dihydro-L-biopterin-d3 is a labeled reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase, is involved in the synthesis of tyrosine and neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM. Applications: Noncompetitive inhibitor of gtp cyclohydrolase i. Group: Coenzymes. Synonyms: 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone; 7,8-Dihydrobiopterin. CAS No. 6779-87-9 (unlabeled). Mole weight: 242.25. Form: Solid. 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone; 7,8-Dihydrobiopterin; 7,8-Dihydro-L-biopterin-d3; 6779-87-9 (unlabeled). Cat No: COEC-091.
Tetrahydrobiopterin (THB) dihydrochloride
Tetrahydrobiopterin (THB) dihydrochloride is an activating Nitric Oxide Synthase (NOS)cofactor used in a variety of applications. The compound is also a known cofactor for the monooxygenases that hydroxylates phenylalanine, tyrosine, and tryptophan. Synthesis of THB has been documented to be the rate limiting step in the metabolism of phenylalanine and the biosynthesis of neurotransmiter amines. In mice, Quinolinic acid (sc-203226) induced convulsions were potentiated with Tetrahydrobiopterindihydrochloride demonstrating that endogenous NO may be involved in stimulating the NMDA receptors. When hypertensive mice were fed THB, but were not introduced to hydralazine or tetrahydroneopterin, they displayed improved cardiac THB stores, phosphorylated phospholamban levels, and diastolic dysfunction. The compound has also been observed as an essential cofactor in the hydroxylation process in mammalian brains. Applications: An activating nos cofactor. Group: Coenzymes. Synonyms: (6R)-5,6,7,8-Tetrahydro-L-biopterindihydrochloride. CAS No. 69056-38-8. Purity: ≥98%. Mole weight: 314.17. Appearance: Powder. Form: Solid. (6R)-5,6,7,8-Tetrahydro-L-biopterindihydrochloride; Tetrahydrobiopterin (THB) dihydrochloride; 69056-38-8. Cat No: COEC-024.
2-N-Acetyl-1',2'-di-O-acetyl-6-biopterin
2-N-Acetyl-1',2'-di-O-acetyl-6-biopterin. Group: Biochemicals. Alternative Names: N-[6-[(1R,2S)-1,2-bis(acetyloxy)propyl]-1,4-dihydro-4-oxo-2-pteridinyl]acetamide; Triacetyl-L-erythro-biopterin. Grades: Highly Purified. CAS No. 81827-31-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C15H17N5O6. US Biological Life Sciences.
Worldwide
(6R)-5,6,7,8-Tetrahydro-L-biopterin 2HCl
Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterindihydrochloride; 6R-BH4; Sapropterin; Sapropterin dihydrochloride; BioMarin T 1401, Biopten, Kuvan, SUN 0588; Shiratori SN 0588. Grades: Highly Purified. CAS No. 69056-38-8,17528-72-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??N?O?; 2(HCl), Molecular Weight: 314.17. US Biological Life Sciences.
Worldwide
(6R)-Tetrahydro-L-biopterin sulfate
(6R)-Tetrahydro-L-biopterin sulfate. Group: Biochemicals. Alternative Names: (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-pteridinone Sulfate. Grades: Highly Purified. CAS No. 103130-44-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C9H17N5O7S. US Biological Life Sciences.
(6S)-Tetrahydro-L-biopterin disulfate. Group: Biochemicals. Alternative Names: (6S)-2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone Disulfate. Grades: Highly Purified. CAS No. 103130-45-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C9H19N5O11S2. US Biological Life Sciences.
Worldwide
7,8-Dihydro-D-Neopterin
7,8-Dihydro-D-Neopterin is an intermediate in the biosynthesis of Biopterin (sc-204781). 7,8-Dihydro-D-Neopterin, also known as Dihydroneopterin, is closely related to tetrahydrobiopterin, an important cofactor in humans. Applications: An intermediate in the biosynthesis of tetrahydrobiopterin. Group: Coenzymes. Synonyms: 7,8-Dihydroneopterin; Dihydroneopterin. CAS No. 1218-98-0. Mole weight: 255.2. Appearance: Powder. Form: Solid. 7,8-Dihydroneopterin; Dihydroneopterin; 7,8-Dihydro-D-Neopterin; 1218-98-0. Cat No: COEC-063.
Biopterin-d3
Labeled Biopterin. A pteridine widely distributed in nature; naturally occurring as the L-erythro-form. Considered as a growth factor for some insects. Fluoresces with a blue color in alkaline solution. Group: Biochemicals. Alternative Names: 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl-d3]-4(1H)-pteridinone; (-)-Biopterin-d3; 6-Biopterin-d3; L-Biopterin-d3; L-erythro-Biopterin-d3; NSC 339699-d3; Pterin H B2-d3. Grades: Highly Purified. CAS No. 1217838-71-5. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Biopterin-D3
Heterocyclic Organic Compound. Alternative Names: 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl-d3]-4(1H)-pteridinone; (-)-Biopterin-d3; 6-Biopterin-d3; L-Biopterin-d3; L-erythro-Biopterin-d3; NSC 339699-d3; Pterin H B2-d3. CAS No. 1217838-71-5. Molecular formula: C9H8D3N5O3. Mole weight: 240.23. Appearance: Brown Solid. Catalog: ACM1217838715.
L-Biopterin
L-Biopterin. Group: Biochemicals. Alternative Names: 6-Biopterin; 2-Amino-4-hydroxy-6- (1, 2-dihydroxypropyl) pteridine; L-Erythro-biopterin. Grades: Highly Purified. CAS No. 22150-76-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C9H11N5O3. US Biological Life Sciences.
Worldwide
L-Biopterin
L-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). It is an important cofactor in the production of many essential neurotransmitters, such as dopamine, seratonin and epinephrine, and plays an important role in the production of nitric oxide in the body. It has been shown to be cytotoxic to melanocytes in vitro, and may be a useful noninvasive biomarker. Synonyms: L-Biopterin; NSC 339699; NSC-339699; NSC339699; AR 1D8544; AR-1D8544; AR1D8544; LS126316; LS-126316; LS 126316; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone; (-)-Biopterin; 6-Biopterin; Biopterin; L-erythro-Biopterin; NSC 339699; Pterin H B2; (1'R,2'S)-Biopterin; L-erythro-6-(1,2-Dihydroxypropyl)pterin. Grades: >95%. CAS No. 22150-76-1. Molecular formula: C9H11N5O3. Mole weight: 273.22.
pteridine reductase
The enzyme from Leishmania (both amastigote and promastigote forms) catalyses the reduction by NADPH of folate and a wide variety of unconjugated pterins, including biopterin, to their tetrahydro forms. It also catalyses the reduction of 7,8-dihydropterins and 7,8-dihydrofolate to their tetrahydro forms. In contrast to EC 1.5.1.3 (dihydrofolate reductase) and EC 1.5.1.34 (6,7-dihydropteridine reductase), pteridine reductase will not catalyse the reduction of the quinonoid form of dihydrobiopterin. The enzyme is specific for NADPH; no activity has been detected with NADH. It also differs from EC 1.5.1.3 (dihydrofolate reductase) in being specific for the Si-face of NADPH. Group: Enzymes. Synonyms: PTR1; pteridine reductase 1. Enzyme Commission Number: EC 1.5.1.33. CAS No. 131384-61-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1515; pteridine reductase; EC 1.5.1.33; 131384-61-7; PTR1; pteridine reductase 1. Cat No: EXWM-1515.
Sapropterin dihydrochloride
Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin also drives autoimmunity. Sapropterin can be used in study of phenylketonuria (PKU) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterindihydrochloride. CAS No. 69056-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0124A.
Sapropterin dihydrochloride
Sapropterin is a naturally occurring cofactor for phenylalanine hydroxylase. Under the trade name Kuvan, sapropterin dihydrochloride is approved for the treatment of hyperphenylalaninaemia and tetrahydrobiopterin deficiency. Synonyms: BioMarin T 1401; Biopten; Kuvan; SUN 0588; Shiratori SN 0588; (6R)-5,6,7,8-TetrahydrobiopterinDihydrochloride; Phenoptin; (R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride; (6R)-Tetrahydrobiopterin hydrochloride; (6R)-5,6,7,8-Tetrahydro-L-BiopterinDihydrochloride. Grades: >98%. CAS No. 69056-38-8. Molecular formula: C9H17Cl2N5O3. Mole weight: 314.17.
Sapropterin Related Compound ((6S)-5,6,7,8-Tetrahydro-L-Biopterin Sulfate)
An impurity of Sapropterin.Sapropterin is an cofactor for phenylalanine hydroxylase. Synonyms: 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-, [6S-[6R*(1S*,2R*)]]-, sulfate (1:x) (salt); (S)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(1H)-one sulfate (1:x); (6S)-5,6,7,8-Tetrahydro-L-erythro-biopterin sulfate; [6S-[6R*(1S*,2R*)]]-2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone sulfate (1:x) (salt); (6S)-Tetrahydro-L-biopterin sulfate salt. Grades: ≥95%. CAS No. 109784-74-9. Molecular formula: C9H15N5O3.xH2SO4. Mole weight: 241.25 (free base).
Tetrahydrobiopterin
Tetrahydrobiopterin, a pteridin derivative, has been found to be a cofactor to form nitric oxide and neurotransmitters serotonin. Synonyms: 5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinon;5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinone;bh4;TETRAHYDRO-L-BIOPTERIN, DIHYDROCHLORIDE;THB, 2HCL;6R-BH4;(6R)-BH4 2HCL;[6R-[6R*(1R*,2S*)]]-2-AMINO-6-(1,2-DIHYDRO. Grades: 98%. CAS No. 17528-72-2. Molecular formula: C9H15N5O3. Mole weight: 241.25.