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Capsaicin analog. A VR1 vaniloid receptor agonist. Group: Biochemicals. Alternative Names: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide; 8-Methyl-N-vanillylnonanamide; 6,7-Dihydrocapsaicin; Dihydrocapsaicin. Grades: Highly Purified. CAS No. 19408-84-5. Pack Sizes: 25mg. US Biological Life Sciences.
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Dihydro Capsaicin
Dihydro Capsaicin is a terpene alkaloid found in Capsicum. Uses: Sterilization. Synonyms: Dihydrocapsaicin; 6,7-Dihydrocapsaicin; N-(4-hydroxy-3-methoxybenzyl)-8-methylnonanamide; 8-Methyl-N-vanillylnonanamide. Grades: >98%. CAS No. 19408-84-5. Molecular formula: C18H29NO3. Mole weight: 307.43.
Dihydrocapsaicin
Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF , Bax , and Caspase-3 expressions, and increased Bcl-2 , Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 19408-84-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0361.
Dihydrocapsaicin
Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-Hydroxy-3-methoxybenzyl). Product Category: Inhibitors. Appearance: White powder. CAS No. 19408-84-5. Molecular formula: C18H29NO3. Mole weight: 307.43. Purity: 0.98. IUPACName: N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide. Canonical SMILES: CC(C)CCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC. Density: 1.026±0.06 g/ml. Product ID: ACM19408845-1. Alfa Chemistry ISO 9001:2015 Certified.
A 784168
A 784168 is a potent and selective TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin) exhibiting no activity against a range of receptors such as TRPA1, GABA, opioid, and purinergic receptors. Synonyms: A 784168; A784168; A-784168; 3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide; 1-[3-(trifluoromethyl)pyridin-2-yl]-N-[4-(trifluoromethylsulfonyl)phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide. Grades: ≥99% by HPLC. CAS No. 824982-41-4. Molecular formula: C19H15F6N3O3S. Mole weight: 479.4.
AMG-9810
AMG-9810 is potent, non-vanilloid and selective TRPV1 receptor antagonist with IC50 value of 17 nM. It inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. It displays antihyperalgesic properties in a rat model of inflammatory pain. It was developed by Amgen. Uses: Amg-9810 displays antihyperalgesic properties. Synonyms: AMG-9810; AMG9810; AMG 9810. (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;(E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enami. Grades: 98%. CAS No. 545395-94-6. Molecular formula: C21H23NO3. Mole weight: 337.41.
AT-121
T-121 is a dual μ-opioid and nociceptin receptor partial agonist (Kis = 16.49 and 3.67 nM, respectively). AT-121 can decrease capsaicin-induced thermal allodynia without increasing scratching activity in rhesus monkeys in a dose-dependent manner. Synonyms: AT-121; 2099681-31-7; N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide; 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine]; SCHEMBL18920959; SCHEMBL20230173; SCHEMBL21179793; DTXSID801336428; GLXC-25688; EX-A8003; AKOS040755934; HY-112692; CS-0062666; Q56448036; N-{2-[1'-(cis-4-Isopropylcyclohexyl)-3-oxo-1H-spiro[isoquinoline-4,4'-piperidin]-2(3H)-yl]ethyl}sulfuric diamide. Grades: ≥95%. CAS No. 2099681-31-7. Molecular formula: C24H38N4O3S. Mole weight: 462.65.
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